TreeWAS – Variant ID: rs9266340

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E10.9 Without complications	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
Chapter IX Diseases of the circulatory system	0.998	0.002
E10.3 With ophthalmic complications	0.988	0.012
I20-I25 Ischaemic heart diseases	0.981	0.019
Chapter II Neoplasms	0.975	0.025
Chapter VI Diseases of the nervous system	0.965	0.035
S40-S49 Injuries to the shoulder and upper arm	0.962	0.038
C15-C26 Malignant neoplasms of digestive organs	0.957	0.043
Chapter XIV Diseases of the genitourinary system	0.957	0.043
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.951	0.049
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.950	0.050
G35-G37 Demyelinating diseases of the central nervous system	0.948	0.052
E14 Unspecified diabetes mellitus	0.945	0.055
E10.4 With neurological complications	0.940	0.060
S42 Fracture of shoulder and upper arm	0.940	0.060
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.937	0.063
I21 Acute myocardial infarction	0.934	0.066
G35 Multiple sclerosis	0.934	0.066
I70-I79 Diseases of arteries, arterioles and capillaries	0.933	0.067
I25 Chronic ischaemic heart disease	0.931	0.069
S60-S69 Injuries to the wrist and hand	0.927	0.073
C43-C44 Melanoma and other malignant neoplasms of skin	0.926	0.074
I21.9 Acute myocardial infarction, unspecified	0.922	0.078
E16 Other disorders of pancreatic internal secretion	0.916	0.084
S50-S59 Injuries to the elbow and forearm	0.915	0.085
Chapter I Certain infectious and parasitic diseases	0.906	0.094
N17-N19 Renal failure	0.900	0.100
N30-N39 Other diseases of urinary system	0.894	0.106
E14.9 Without complications	0.893	0.107
I25.2 Old myocardial infarction	0.893	0.107
E16.2 Hypoglycaemia, unspecified	0.891	0.109
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.890	0.110
S20-S29 Injuries to the thorax	0.886	0.114
C44 Other malignant neoplasms of skin	0.883	0.117
D37-D48 Neoplasms of uncertain or unknown behaviour	0.881	0.119
E10.1 With ketoacidosis	0.881	0.119
T36-T50 Poisoning by drugs, medicaments and biological substances	0.876	0.124
S42.0 Fracture of clavicle	0.873	0.127
Chapter XX External causes of morbidity and mortality	0.867	0.133
C18 Malignant neoplasm of colon	0.866	0.134
N18 Chronic renal failure	0.863	0.137
N32 Other disorders of bladder	0.862	0.138
N32.8 Other specified disorders of bladder	0.854	0.146
I24 Other acute ischaemic heart diseases	0.851	0.149
S52 Fracture of forearm	0.849	0.151
S42.2 Fracture of upper end of humerus	0.849	0.151
N00-N08 Glomerular diseases	0.849	0.151
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.844	0.156
C44.1 Skin of eyelid, including canthus	0.843	0.157
T88 Other complications of surgical and medical care, not elsewhere classified	0.842	0.157
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.835	0.165
N10-N16 Renal tubulo-interstitial diseases	0.832	0.168
I60-I69 Cerebrovascular diseases	0.831	0.169
A00-A09 Intestinal infectious diseases	0.830	0.170
I74 Arterial embolism and thrombosis	0.827	0.173
S42.00 Fracture of clavicle (closed)	0.826	0.174
E65-E68 Obesity and other hyperalimentation	0.825	0.175
I80 Phlebitis and thrombophlebitis	0.818	0.182
C25 Malignant neoplasm of pancreas	0.817	0.183
E10.5 With peripheral circulatory complications	0.816	0.184
G90-G99 Other disorders of the nervous system	0.816	0.184
T66-T78 Other and unspecified effects of external causes	0.815	0.185
Chapter XI Diseases of the digestive system	0.815	0.185
T81 Complications of procedures, not elsewhere classified	0.813	0.187
I71 Aortic aneurysm and dissection	0.811	0.189
S60 Superficial injury of wrist and hand	0.809	0.191
E07 Other disorders of thyroid	0.808	0.192
C44.7 Skin of lower limb, including hip	0.807	0.193
C50-C50 Malignant neoplasm of breast	0.806	0.194
C19 Malignant neoplasm of rectosigmoid junction	0.803	0.197
A04 Other bacterial intestinal infections	0.796	0.204
N18.9 Chronic renal failure, unspecified	0.792	0.208
Chapter XXII Codes for special purposes	0.790	0.210
E05 Thyrotoxicosis [hyperthyroidism]	0.790	0.210
N30 Cystitis	0.784	0.216
S42.20 Fracture of upper end of humerus (closed)	0.784	0.216
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.781	0.219
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.780	0.220
I82 Other venous embolism and thrombosis	0.780	0.220
T88.7 Unspecified adverse effect of drug or medicament	0.779	0.221
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.772	0.228
C15 Malignant neoplasm of oesophagus	0.771	0.229
S61 Open wound of wrist and hand	0.769	0.231
I84 Haemorrhoids	0.769	0.231
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.769	0.231
Q20-Q28 Congenital malformations of the circulatory system	0.768	0.232
K90-K93 Other diseases of the digestive system	0.767	0.233
S52.5 Fracture of lower end of radius	0.766	0.234
S22 Fracture of rib(s), sternum and thoracic spine	0.765	0.235
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.763	0.237
G30-G32 Other degenerative diseases of the nervous system	0.763	0.237
I25.9 Chronic ischaemic heart disease, unspecified	0.762	0.238
C26 Malignant neoplasm of other and ill-defined digestive organs	0.762	0.238
G00-G09 Inflammatory diseases of the central nervous system	0.762	0.238
T79-T79 Certain early complications of trauma	0.761	0.239
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.760	0.240
N99-N99 Other disorders of the genitourinary system	0.759	0.241
C44.0 Skin of lip	0.758	0.242
S42.1 Fracture of scapula	0.757	0.243
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.757	0.243
W00-W19 Falls	0.756	0.244
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.754	0.246
K90 Intestinal malabsorption	0.753	0.247
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.753	0.247
S90-S99 Injuries to the ankle and foot	0.750	0.250
I74.5 Embolism and thrombosis of iliac artery	0.748	0.252
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.747	0.253
A04.8 Other specified bacterial intestinal infections	0.747	0.253
N17 Acute renal failure	0.747	0.253
I25.5 Ischaemic cardiomyopathy	0.746	0.254
I84.6 Residual haemorrhoidal skin tags	0.746	0.254
W20-W49 Exposure to inanimate mechanical forces	0.745	0.255
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.745	0.255
K90.0 Coeliac disease	0.744	0.256
I63 Cerebral infarction	0.742	0.258
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.742	0.258
I85 Oesophageal varices	0.741	0.259
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.741	0.259
I81 Portal vein thrombosis	0.741	0.259
S66 Injury of muscle and tendon at wrist and hand level	0.740	0.260
E14.3 With ophthalmic complications	0.740	0.260
K55-K64 Other diseases of intestines	0.738	0.262
C18.2 Ascending colon	0.738	0.262
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.737	0.263
N05 Unspecified nephritic syndrome	0.737	0.263
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.737	0.263
I86 Varicose veins of other sites	0.736	0.264
Chapter VII Diseases of the eye and adnexa	0.736	0.264
E40-E46 Malnutrition	0.731	0.269
C18.7 Sigmoid colon	0.731	0.269
K62.1 Rectal polyp	0.731	0.269
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.730	0.270
I05-I09 Chronic rheumatic heart diseases	0.725	0.275
I70 Atherosclerosis	0.724	0.276
K62 Other diseases of anus and rectum	0.724	0.276
I24.9 Acute ischaemic heart disease, unspecified	0.724	0.276
N18.3 Chronic kidney disease, stage 3	0.723	0.277
T83.0 Mechanical complication of urinary (indwelling) catheter	0.721	0.279
E20-E35 Disorders of other endocrine glands	0.719	0.281
E70-E90 Metabolic disorders	0.718	0.282
N20-N23 Urolithiasis	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E13 Other specified diabetes mellitus	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
G50-G59 Nerve, nerve root and plexus disorders	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
G37 Other demyelinating diseases of central nervous system	0.717	0.283
I00-I02 Acute rheumatic fever	0.715	0.284
C43 Malignant melanoma of skin	0.715	0.285
I80.8 Phlebitis and thrombophlebitis of other sites	0.714	0.286
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.714	0.286
C64-C68 Malignant neoplasms of urinary tract	0.713	0.287
S64 Injury of nerves at wrist and hand level	0.713	0.287
D00-D09 In situ neoplasms	0.712	0.288
A30-A49 Other bacterial diseases	0.710	0.290
C18.6 Descending colon	0.709	0.291
S52.50 Fracture of lower end of radius (closed)	0.707	0.293
S52.6 Fracture of lower end of both ulna and radius	0.706	0.294
I77 Other disorders of arteries and arterioles	0.704	0.295
I72 Other aneurysm	0.704	0.296
K63 Other diseases of intestine	0.704	0.296
I23 Certain current complications following acute myocardial infarction	0.703	0.296
I25.8 Other forms of chronic ischaemic heart disease	0.703	0.297
N13 Obstructive and reflux uropathy	0.703	0.297
A04.7 Enterocolitis due to Clostridium difficile	0.702	0.298
N32.3 Diverticulum of bladder	0.701	0.299
E66 Obesity	0.700	0.300
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.699	0.301
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.699	0.301
C40-C41 Malignant neoplasms of bone and articular cartilage	0.699	0.301
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.699	0.301
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.699	0.301
H30-H36 Disorders of choroid and retina	0.697	0.303
I21.0 Acute transmural myocardial infarction of anterior wall	0.696	0.304
B35-B49 Mycoses	0.695	0.305
I61 Intracerebral haemorrhage	0.694	0.306
S20 Superficial injury of thorax	0.693	0.307
I87 Other disorders of veins	0.692	0.307
S42.3 Fracture of shaft of humerus	0.692	0.308
G70-G73 Diseases of myoneural junction and muscle	0.692	0.308
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.692	0.308
Chapter V Mental and behavioural disorders	0.692	0.308
T15-T19 Effects of foreign body entering through natural orifice	0.690	0.309
S60.8 Other superficial injuries of wrist and hand	0.690	0.310
S49 Other and unspecified injuries of shoulder and upper arm	0.690	0.310
S48 Traumatic amputation of shoulder and upper arm	0.690	0.310
S46 Injury of muscle and tendon at shoulder and upper arm level	0.690	0.310
S45 Injury of blood vessels at shoulder and upper arm level	0.690	0.310
S44 Injury of nerves at shoulder and upper arm level	0.690	0.310
S41 Open wound of shoulder and upper arm	0.690	0.310
S47 Crushing injury of shoulder and upper arm	0.690	0.310
I25.3 Aneurysm of heart	0.689	0.310
K63.5 Polyp of colon	0.688	0.312
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.688	0.312
C21 Malignant neoplasm of anus and anal canal	0.686	0.314
C17 Malignant neoplasm of small intestine	0.686	0.314
C23 Malignant neoplasm of gallbladder	0.686	0.314
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.686	0.314
C50 Malignant neoplasm of breast	0.685	0.314
H36 Retinal disorders in diseases classified elsewhere	0.684	0.316
T81.3 Disruption of operation wound, not elsewhere classified	0.684	0.316
T78 Adverse effects, not elsewhere classified	0.683	0.317
C18.5 Splenic flexure	0.683	0.317
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.682	0.318
E15 Nondiabetic hypoglycaemic coma	0.682	0.318
S68 Traumatic amputation of wrist and hand	0.682	0.318
Q00-Q07 Congenital malformations of the nervous system	0.681	0.319
X20-X29 Contact with venomous animals and plants	0.681	0.319
I88 Nonspecific lymphadenitis	0.681	0.319
E11 Non-insulin-dependent diabetes mellitus	0.681	0.319
D60-D64 Aplastic and other anaemias	0.680	0.320
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.680	0.320
G36 Other acute disseminated demyelination	0.680	0.320
E06 Thyroiditis	0.679	0.321
S50 Superficial injury of forearm	0.678	0.321
K65-K67 Diseases of peritoneum	0.678	0.322
E14.8 With unspecified complications	0.677	0.322
E14.7 With multiple complications	0.677	0.322
E14.6 With other specified complications	0.677	0.322
E14.5 With peripheral circulatory complications	0.677	0.322
E14.4 With neurological complications	0.677	0.322
E14.2 Withrenal complications	0.677	0.322
E14.1 With ketoacidosis	0.677	0.322
E14.0 With coma	0.677	0.322
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.675	0.324
N25-N29 Other disorders of kidney and ureter	0.675	0.325
H36.0 Diabetic retinopathy	0.675	0.325
S42.9 Fracture of shoulder girdle, part unspecified	0.674	0.326
S42.8 Fracture of other parts of shoulder and upper arm	0.674	0.326
S42.7 Multiple fractures of clavicle, scapula and humerus	0.674	0.326
N04 Nephrotic syndrome	0.673	0.327
S40 Superficial injury of shoulder and upper arm	0.672	0.328
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.672	0.328
T87 Complications peculiar to reattachment and amputation	0.672	0.328
T86 Failure and rejection of transplanted organs and tissues	0.672	0.328
T80 Complications following infusion, transfusion and therapeutic injection	0.672	0.328
B95-B98 Bacterial, viral and other infectious agents	0.671	0.329
E07.9 Disorder of thyroid, unspecified	0.671	0.329
N18.4 Chronic kidney disease, stage 4	0.670	0.330
I21.X Presumed acute myicardial infaction (unconfirmed)	0.670	0.330
I21.3 Acute transmural myocardial infarction of unspecified site	0.670	0.330
T83.1 Mechanical complication of other urinary devices and implants	0.670	0.330
K40-K46 Hernia	0.669	0.331
S27 Injury of other and unspecified intrathoracic organs	0.668	0.332
C44.5 Skin of trunk	0.668	0.332
C25.9 Pancreas, unspecified	0.668	0.332
T81.7 Vascular complications following a procedure, not elsewhere classified	0.668	0.332
I25.6 Silent myocardial ischaemia	0.667	0.333
I25.4 Coronary artery aneurysm	0.667	0.333
I25.0 Atherosclerotic cardiovascular disease, so described	0.667	0.333
S80-S89 Injuries to the knee and lower leg	0.667	0.333
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.667	0.333
Q50-Q56 Congenital malformations of genital organs	0.665	0.335
S69 Other and unspecified injuries of wrist and hand	0.665	0.335
S67 Crushing injury of wrist and hand	0.665	0.335
S65 Injury of blood vessels at wrist and hand level	0.665	0.335
C18.4 Transverse colon	0.664	0.336
D46 Myelodysplastic syndromes	0.664	0.336
I24.8 Other forms of acute ischaemic heart disease	0.663	0.337
N18.2 Chronic kidney disease, stage 2	0.663	0.337
N60-N64 Disorders of breast	0.663	0.337
I84.7 Unspecified thrombosed haemorrhoids	0.663	0.337
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.663	0.337
N18.5 Chronic kidney disease, stage 5	0.661	0.339
C25.0 Head of pancreas	0.661	0.339
V40-V49 Car occupant injured in transport accident	0.660	0.339
D47.3 Essential (haemorrhagic) thrombocythaemia	0.660	0.339
S52.1 Fracture of upper end of radius	0.660	0.340
Q21 Congenital malformations of cardiac septa	0.660	0.340
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.660	0.340
N03 Chronic nephritic syndrome	0.660	0.340
E16.9 Disorder of pancreatic internal secretion, unspecified	0.657	0.343
E16.8 Other specified disorders of pancreatic internal secretion	0.657	0.343
E16.4 Abnormal secretion of gastrin	0.657	0.343
E16.3 Increased secretion of glucagon	0.657	0.343
E16.1 Other hypoglycaemia	0.657	0.343
E16.0 Drug-induced hypoglycaemia without coma	0.657	0.343
S59 Other and unspecified injuries of forearm	0.656	0.344
S58 Traumatic amputation of forearm	0.656	0.344
S57 Crushing injury of forearm	0.656	0.344
S56 Injury of muscle and tendon at forearm level	0.656	0.344
S55 Injury of blood vessels at forearm level	0.656	0.344
S54 Injury of nerves at forearm level	0.656	0.344
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.656	0.344
S51 Open wound of forearm	0.656	0.344
T81.8 Other complications of procedures, not elsewhere classified	0.655	0.345
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.655	0.345
C24.0 Extrahepatic bile duct	0.655	0.345
I22 Subsequent myocardial infarction	0.655	0.345
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.654	0.346
T59 Toxic effect of other gases, fumes and vapours	0.652	0.348
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.652	0.348
G99 Other disorders of nervous system in diseases classified elsewhere	0.651	0.349
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.650	0.350
Q38-Q45 Other congenital malformations of the digestive system	0.650	0.350
B99-B99 Other infectious diseases	0.649	0.350
B90-B94 Sequelae of infectious and parasitic diseases	0.649	0.350
B85-B89 Pediculosis, acariasis and other infestations	0.649	0.350
B65-B83 Helminthiases	0.649	0.350
B50-B64 Protozoal diseases	0.649	0.350
B20-B24 Human immunodeficiency virus [HIV] disease	0.649	0.350
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.649	0.350
A80-A89 Viral infections of the central nervous system	0.649	0.350
A75-A79 Rickettsioses	0.649	0.350
A70-A74 Other diseases caused by chlamydiae	0.649	0.350
A65-A69 Other spirochaetal diseases	0.649	0.350
A50-A64 Infections with a predominantly sexual mode of transmission	0.649	0.350
A20-A28 Certain zoonotic bacterial diseases	0.649	0.350
A15-A19 Tuberculosis	0.649	0.350
T51 Toxic effect of alcohol	0.649	0.351
E66.8 Other obesity	0.649	0.351
V10-V19 Pedal cyclist injured in transport accident	0.647	0.353
X40-X49 Accidental poisoning by and exposure to noxious substances	0.647	0.353
N30.3 Trigonitis	0.647	0.353
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.647	0.353
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.646	0.354
E05.0 Thyrotoxicosis with diffuse goitre	0.645	0.355
G80-G83 Cerebral palsy and other paralytic syndromes	0.645	0.355
I60 Subarachnoid haemorrhage	0.645	0.355
S60.9 Superficial injury of wrist and hand, unspecified	0.645	0.355
B15-B19 Viral hepatitis	0.644	0.355
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.643	0.357
S42.4 Fracture of lower end of humerus	0.643	0.357
S61.9 Open wound of wrist and hand, part unspecified	0.642	0.358
N37 Urethral disorders in diseases classified elsewhere	0.641	0.359
N34 Urethritis and urethral syndrome	0.641	0.359
N33 Bladder disorders in diseases classified elsewhere	0.641	0.359
T63 Toxic effect of contact with venomous animals	0.640	0.360
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.639	0.361
S22.1 Multiple fractures of thoracic spine	0.639	0.361
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.638	0.361
Q80-Q89 Other congenital malformations	0.638	0.361
Q60-Q64 Congenital malformations of the urinary system	0.638	0.361
Q35-Q37 Cleft lip and cleft palate	0.638	0.361
Q30-Q34 Congenital malformations of the respiratory system	0.638	0.361
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.638	0.361
I26 Pulmonary embolism	0.638	0.362
N17.9 Acute renal failure, unspecified	0.638	0.362
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.637	0.363
G91 Hydrocephalus	0.637	0.363
N30.8 Other cystitis	0.637	0.363
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.637	0.363
K35-K38 Diseases of appendix	0.636	0.364
C51-C58 Malignant neoplasms of female genital organs	0.636	0.364
S29 Other and unspecified injuries of thorax	0.635	0.364
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.635	0.364
S26 Injury of heart	0.635	0.364
S25 Injury of blood vessels of thorax	0.635	0.364
S24 Injury of nerves and spinal cord at thorax level	0.635	0.364
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.635	0.364
S21 Open wound of thorax	0.635	0.364
K41 Femoral hernia	0.635	0.365
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.634	0.365
C44.9 Malignant neoplasm of skin, unspecified	0.633	0.366
C44.8 Overlapping lesion of skin	0.633	0.366
A08 Viral and other specified intestinal infections	0.633	0.367
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.633	0.367
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.632	0.368
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.632	0.368
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.632	0.368
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.632	0.368
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.631	0.369
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.631	0.369
V80-V89 Other land transport accidents	0.631	0.369
K70-K77 Diseases of liver	0.630	0.370
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.629	0.371
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.629	0.371
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.628	0.372
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.628	0.372
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.628	0.372
T46 Poisoning by agents primarily affecting the cardiovascular system	0.628	0.372
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.628	0.372
T41 Poisoning by anaesthetics and therapeutic gases	0.628	0.372
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.628	0.372
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.628	0.372
T36 Poisoning by systemic antibiotics	0.628	0.372
I63.8 Other cerebral infarction	0.627	0.373
S42.10 Fracture of scapula (closed)	0.627	0.373
G90 Disorders of autonomic nervous system	0.626	0.373
S70-S79 Injuries to the hip and thigh	0.626	0.374
S42.01 Fracture of clavicle (open)	0.626	0.374
I84.0 Internal thrombosed haemorrhoids	0.626	0.374
N05.2 Diffuse membranous glomerulonephritis	0.625	0.374
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.624	0.375
N32.1 Vesicointestinal fistula	0.624	0.376
K62.3 Rectal prolapse	0.622	0.378
Y35-Y36 Legal intervention and operations of war	0.622	0.378
Y10-Y34 Event of undetermined intent	0.622	0.378
Y00-Y09 Assault	0.622	0.378
X85-X99 Assault	0.622	0.378
X58-X59 Accidental exposure to other and unspecified factors	0.622	0.378
X50-X57 Overexertion, travel and privation	0.622	0.378
X30-X39 Exposure to forces of nature	0.622	0.378
X10-X19 Contact with heat and hot substances	0.622	0.378
X00-X09 Exposure to smoke, fire and flames	0.622	0.378
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.622	0.378
W75-W84 Other accidental threats to breathing	0.622	0.378
W65-W74 Accidental drowning and submersion	0.622	0.378
W50-W64 Exposure to animate mechanical forces	0.622	0.378
V98-V99 Other and unspecified transport accidents	0.622	0.378
V95-V97 Air and space transport accidents	0.622	0.378
V90-V94 Water transport accidents	0.622	0.378
V70-V79 Bus occupant injured in transport accident	0.622	0.378
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.622	0.378
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.622	0.378
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.622	0.378
V01-V09 Pedestrian injured in transport accident	0.622	0.378
C26.0 Intestinal tract, part unspecified	0.621	0.378
C18.8 Overlapping lesion of colon	0.621	0.379
C18.3 Hepatic flexure	0.621	0.379
C18.1 Appendix	0.621	0.379
G56 Mononeuropathies of upper limb	0.621	0.379
I84.5 External haemorrhoids without complication	0.620	0.380
T42.4 Benzodiazepines	0.620	0.380
A49 Bacterial infection of unspecified site	0.619	0.381
N18.8 Other chronic renal failure	0.619	0.381
N18.1 Chronic kidney disease, stage 1	0.619	0.381
N21 Calculus of lower urinary tract	0.619	0.381
T43.3 Phenothiazine antipsychotics and neuroleptics	0.618	0.382
N32.4 Rupture of bladder, nontraumatic	0.618	0.382
N32.2 Vesical fistula, not elsewhere classified	0.618	0.382
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.617	0.383
C20 Malignant neoplasm of rectum	0.616	0.384
I82.9 Embolism and thrombosis of unspecified vein	0.616	0.384
I82.8 Embolism and thrombosis of other specified veins	0.616	0.384
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.616	0.384
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.615	0.385
K62.0 Anal polyp	0.615	0.385
N30.1 Interstitial cystitis (chronic)	0.614	0.385
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.613	0.387
C15.9 Oesophagus, unspecified	0.612	0.388
W17 Other fall from one level to another	0.612	0.388
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.611	0.389
N13.3 Other and unspecified hydronephrosis	0.610	0.390
I24.1 Dressler's syndrome	0.610	0.390
T85 Complications of other internal prosthetic devices, implants and grafts	0.610	0.390
I95-I99 Other and unspecified disorders of the circulatory system	0.609	0.391
I85.0 Oesophageal varices with bleeding	0.609	0.391
S52.9 Fracture of forearm, part unspecified	0.608	0.391
S52.8 Fracture of other parts of forearm	0.608	0.391
S52.7 Multiple fractures of forearm	0.608	0.391
S52.4 Fracture of shafts of both ulna and radius	0.608	0.391
S52.3 Fracture of shaft of radius	0.608	0.391
S52.2 Fracture of shaft of ulna	0.608	0.391
S42.21 Fracture of upper end of humerus (open)	0.608	0.391
N07 Hereditary nephropathy, not elsewhere classified	0.608	0.391
N06 Isolated proteinuria with specified morphological lesion	0.608	0.391
N01 Rapidly progressive nephritic syndrome	0.608	0.391
N00 Acute nephritic syndrome	0.608	0.391
N08 Glomerular disorders in diseases classified elsewhere	0.608	0.392
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.608	0.392
C66 Malignant neoplasm of ureter	0.608	0.392
G20-G26 Extrapyramidal and movement disorders	0.607	0.393
V20-V29 Motorcycle rider injured in transport accident	0.606	0.394
I78 Diseases of capillaries	0.606	0.394
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.605	0.395
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.605	0.395
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.605	0.395
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.605	0.395
T83.2 Mechanical complication of graft of urinary organ	0.605	0.395
S52.60 Fracture of lower end of both ulna and radius (closed)	0.604	0.395
T88.9 Complication of surgical and medical care, unspecified	0.604	0.396
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.604	0.396
T88.5 Other complications of anaesthesia	0.604	0.396
T88.3 Malignant hyperthermia due to anaesthesis	0.604	0.396
T88.2 Shock due to anaesthesia	0.604	0.396
T88.1 Other complications following immunisation, not elsewhere classified	0.604	0.396
T88.0 Infection following immunisation	0.604	0.396
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.604	0.396
D64 Other anaemias	0.604	0.396
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.603	0.397
Y60-Y69 Misadventures to patients during surgical and medical care	0.601	0.399
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.601	0.399

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations