TreeWAS – Variant ID: rs9267660

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10.9 Without complications	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
S50-S59 Injuries to the elbow and forearm	0.992	0.008
Chapter XI Diseases of the digestive system	0.989	0.011
E10.3 With ophthalmic complications	0.988	0.012
S52 Fracture of forearm	0.986	0.014
K90-K93 Other diseases of the digestive system	0.985	0.015
K90 Intestinal malabsorption	0.983	0.017
Chapter VI Diseases of the nervous system	0.983	0.017
K90.0 Coeliac disease	0.980	0.020
G35-G37 Demyelinating diseases of the central nervous system	0.976	0.024
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.972	0.028
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.970	0.030
G35 Multiple sclerosis	0.970	0.030
S52.5 Fracture of lower end of radius	0.969	0.031
S52.50 Fracture of lower end of radius (closed)	0.957	0.043
Chapter VII Diseases of the eye and adnexa	0.940	0.060
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.935	0.065
E10.4 With neurological complications	0.934	0.066
S40-S49 Injuries to the shoulder and upper arm	0.933	0.067
S20-S29 Injuries to the thorax	0.931	0.069
D60-D64 Aplastic and other anaemias	0.927	0.073
Chapter II Neoplasms	0.924	0.076
E10.1 With ketoacidosis	0.922	0.078
H30-H36 Disorders of choroid and retina	0.915	0.085
S60-S69 Injuries to the wrist and hand	0.912	0.088
Chapter V Mental and behavioural disorders	0.908	0.092
E05 Thyrotoxicosis [hyperthyroidism]	0.906	0.094
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.903	0.097
T81 Complications of procedures, not elsewhere classified	0.902	0.098
K40-K46 Hernia	0.892	0.108
S42 Fracture of shoulder and upper arm	0.890	0.110
H36 Retinal disorders in diseases classified elsewhere	0.889	0.111
E16 Other disorders of pancreatic internal secretion	0.888	0.112
Chapter I Certain infectious and parasitic diseases	0.886	0.114
E20-E35 Disorders of other endocrine glands	0.884	0.116
C43-C44 Melanoma and other malignant neoplasms of skin	0.881	0.119
E07 Other disorders of thyroid	0.879	0.121
E11 Non-insulin-dependent diabetes mellitus	0.876	0.124
E14 Unspecified diabetes mellitus	0.873	0.127
T88 Other complications of surgical and medical care, not elsewhere classified	0.872	0.128
D64 Other anaemias	0.872	0.128
K55-K64 Other diseases of intestines	0.872	0.128
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.871	0.129
H36.0 Diabetic retinopathy	0.870	0.130
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.870	0.130
Chapter XX External causes of morbidity and mortality	0.867	0.133
E10.5 With peripheral circulatory complications	0.864	0.136
T66-T78 Other and unspecified effects of external causes	0.863	0.137
K70-K77 Diseases of liver	0.859	0.141
E16.2 Hypoglycaemia, unspecified	0.855	0.145
G90-G99 Other disorders of the nervous system	0.853	0.147
C44 Other malignant neoplasms of skin	0.850	0.150
K90.9 Intestinal malabsorption, unspecified	0.844	0.155
K63 Other diseases of intestine	0.844	0.156
K62.1 Rectal polyp	0.841	0.159
K62 Other diseases of anus and rectum	0.839	0.161
S52.1 Fracture of upper end of radius	0.839	0.161
D64.9 Anaemia, unspecified	0.833	0.167
K63.5 Polyp of colon	0.831	0.169
S52.6 Fracture of lower end of both ulna and radius	0.830	0.170
D37-D48 Neoplasms of uncertain or unknown behaviour	0.830	0.170
D69 Purpura and other haemorrhagic conditions	0.826	0.174
E11.3 With ophthalmic complications	0.824	0.176
E05.9 Thyrotoxicosis, unspecified	0.823	0.177
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.822	0.178
K35-K38 Diseases of appendix	0.822	0.178
S22 Fracture of rib(s), sternum and thoracic spine	0.819	0.181
S80-S89 Injuries to the knee and lower leg	0.816	0.184
D00-D09 In situ neoplasms	0.810	0.190
K41 Femoral hernia	0.810	0.190
S42.0 Fracture of clavicle	0.809	0.191
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.809	0.191
E65-E68 Obesity and other hyperalimentation	0.801	0.199
K42 Umbilical hernia	0.800	0.200
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.796	0.204
T81.3 Disruption of operation wound, not elsewhere classified	0.794	0.206
E07.9 Disorder of thyroid, unspecified	0.793	0.207
T88.7 Unspecified adverse effect of drug or medicament	0.790	0.210
H46-H48 Disorders of optic nerve and visual pathways	0.789	0.211
C64-C68 Malignant neoplasms of urinary tract	0.785	0.215
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.784	0.216
S20 Superficial injury of thorax	0.775	0.225
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.774	0.226
C50-C50 Malignant neoplasm of breast	0.774	0.226
D50-D53 Nutritional anaemias	0.772	0.228
E14.9 Without complications	0.771	0.229
C44.7 Skin of lower limb, including hip	0.770	0.230
S60 Superficial injury of wrist and hand	0.762	0.238
D61 Other aplastic anaemias	0.762	0.238
T81.8 Other complications of procedures, not elsewhere classified	0.755	0.245
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.753	0.247
C44.1 Skin of eyelid, including canthus	0.752	0.248
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.751	0.249
S42.00 Fracture of clavicle (closed)	0.751	0.249
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.751	0.249
B25-B34 Other viral diseases	0.750	0.249
S64 Injury of nerves at wrist and hand level	0.750	0.250
G37 Other demyelinating diseases of central nervous system	0.749	0.251
F60-F69 Disorders of adult personality and behaviour	0.744	0.256
S50 Superficial injury of forearm	0.743	0.257
D62 Acute posthaemorrhagic anaemia	0.740	0.260
Q20-Q28 Congenital malformations of the circulatory system	0.739	0.261
H33 Retinal detachments and breaks	0.739	0.261
H40-H42 Glaucoma	0.738	0.262
D68 Other coagulation defects	0.738	0.262
T78 Adverse effects, not elsewhere classified	0.737	0.263
S61 Open wound of wrist and hand	0.737	0.263
H34 Retinal vascular occlusions	0.736	0.264
H55-H59 Other disorders of eye and adnexa	0.734	0.266
W00-W19 Falls	0.734	0.266
S52.10 Fracture of upper end of radius (closed)	0.733	0.267
E21.3 Hyperparathyroidism, unspecified	0.731	0.269
E11.6 With other specified complications	0.729	0.271
K62.3 Rectal prolapse	0.728	0.272
D69.3 Idiopathic thrombocytopenic purpura	0.727	0.273
S52.0 Fracture of upper end of ulna	0.727	0.273
A00-A09 Intestinal infectious diseases	0.726	0.274
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.725	0.275
G20-G26 Extrapyramidal and movement disorders	0.724	0.275
C44.0 Skin of lip	0.724	0.275
K55 Vascular disorders of intestine	0.724	0.276
S42.3 Fracture of shaft of humerus	0.723	0.277
T79-T79 Certain early complications of trauma	0.721	0.279
S52.60 Fracture of lower end of both ulna and radius (closed)	0.719	0.281
C15-C26 Malignant neoplasms of digestive organs	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E13 Other specified diabetes mellitus	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.715	0.285
T86 Failure and rejection of transplanted organs and tissues	0.715	0.285
K70 Alcoholic liver disease	0.715	0.285
K63.4 Enteroptosis	0.715	0.285
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.715	0.285
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.714	0.286
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.714	0.286
S27 Injury of other and unspecified intrathoracic organs	0.712	0.288
S59 Other and unspecified injuries of forearm	0.711	0.289
S58 Traumatic amputation of forearm	0.711	0.289
S57 Crushing injury of forearm	0.711	0.289
S56 Injury of muscle and tendon at forearm level	0.711	0.289
S55 Injury of blood vessels at forearm level	0.711	0.289
S54 Injury of nerves at forearm level	0.711	0.289
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.711	0.289
F40-F48 Neurotic, stress-related and somatoform disorders	0.711	0.289
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.709	0.291
Chapter XXII Codes for special purposes	0.708	0.292
S42.1 Fracture of scapula	0.708	0.292
K72 Hepatic failure, not elsewhere classified	0.707	0.293
S52.9 Fracture of forearm, part unspecified	0.707	0.293
S52.8 Fracture of other parts of forearm	0.707	0.293
S52.7 Multiple fractures of forearm	0.707	0.293
S52.4 Fracture of shafts of both ulna and radius	0.707	0.293
S52.3 Fracture of shaft of radius	0.707	0.293
S52.2 Fracture of shaft of ulna	0.707	0.293
C44.5 Skin of trunk	0.706	0.294
K93 Disorders of other digestive organs in diseases classified elsewhere	0.706	0.294
B35-B49 Mycoses	0.706	0.294
K42.0 Umbilical hernia with obstruction, without gangrene	0.706	0.294
K90.8 Other intestinal malabsorption	0.705	0.295
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.705	0.295
K90.3 Pancreatic steatorrhoea	0.705	0.295
K90.2 Blind loop syndrome, not elsewhere classified	0.705	0.295
K90.1 Tropical sprue	0.705	0.295
T83.0 Mechanical complication of urinary (indwelling) catheter	0.705	0.295
G70-G73 Diseases of myoneural junction and muscle	0.704	0.295
G00-G09 Inflammatory diseases of the central nervous system	0.704	0.295
C67 Malignant neoplasm of bladder	0.704	0.296
G36 Other acute disseminated demyelination	0.700	0.300
T83.1 Mechanical complication of other urinary devices and implants	0.700	0.300
E05.0 Thyrotoxicosis with diffuse goitre	0.699	0.301
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.699	0.301
S51 Open wound of forearm	0.698	0.302
S40 Superficial injury of shoulder and upper arm	0.697	0.303
G91 Hydrocephalus	0.697	0.303
D55-D59 Haemolytic anaemias	0.697	0.303
D69.6 Thrombocytopenia, unspecified	0.696	0.303
T87 Complications peculiar to reattachment and amputation	0.696	0.304
T80 Complications following infusion, transfusion and therapeutic injection	0.696	0.304
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.696	0.304
S66 Injury of muscle and tendon at wrist and hand level	0.695	0.305
S52.51 Fracture of lower end of radius (open)	0.695	0.305
G30-G32 Other degenerative diseases of the nervous system	0.694	0.306
F30-F39 Mood [affective] disorders	0.694	0.306
S29 Other and unspecified injuries of thorax	0.691	0.309
T83.3 Mechanical complication of intra-uterine contraceptive device	0.689	0.311
E70-E90 Metabolic disorders	0.689	0.311
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.688	0.312
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.687	0.312
D06 Carcinoma in situ of cervix uteri	0.686	0.314
K75 Other inflammatory liver diseases	0.686	0.314
X20-X29 Contact with venomous animals and plants	0.684	0.316
K36 Other appendicitis	0.682	0.318
T85 Complications of other internal prosthetic devices, implants and grafts	0.681	0.319
S49 Other and unspecified injuries of shoulder and upper arm	0.678	0.321
B95-B98 Bacterial, viral and other infectious agents	0.678	0.322
V40-V49 Car occupant injured in transport accident	0.678	0.322
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.678	0.322
S90-S99 Injuries to the ankle and foot	0.677	0.323
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.676	0.323
T36-T50 Poisoning by drugs, medicaments and biological substances	0.676	0.324
K43 Ventral hernia	0.676	0.324
H43-H45 Disorders of vitreous body and globe	0.675	0.325
T15-T19 Effects of foreign body entering through natural orifice	0.674	0.326
S70-S79 Injuries to the hip and thigh	0.674	0.326
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.674	0.326
G50-G59 Nerve, nerve root and plexus disorders	0.673	0.327
S42.4 Fracture of lower end of humerus	0.673	0.327
T68 Hypothermia	0.672	0.328
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.670	0.330
E15 Nondiabetic hypoglycaemic coma	0.670	0.330
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.670	0.330
E06 Thyroiditis	0.669	0.330
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.669	0.331
Q80-Q89 Other congenital malformations	0.669	0.331
S48 Traumatic amputation of shoulder and upper arm	0.669	0.331
S46 Injury of muscle and tendon at shoulder and upper arm level	0.669	0.331
S45 Injury of blood vessels at shoulder and upper arm level	0.669	0.331
S44 Injury of nerves at shoulder and upper arm level	0.669	0.331
S41 Open wound of shoulder and upper arm	0.669	0.331
S47 Crushing injury of shoulder and upper arm	0.669	0.331
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.667	0.333
S26 Injury of heart	0.667	0.333
S25 Injury of blood vessels of thorax	0.667	0.333
S24 Injury of nerves and spinal cord at thorax level	0.667	0.333
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.667	0.333
S21 Open wound of thorax	0.667	0.333
C50 Malignant neoplasm of breast	0.666	0.334
B15-B19 Viral hepatitis	0.665	0.335
S42.2 Fracture of upper end of humerus	0.665	0.335
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.665	0.335
G95 Other diseases of spinal cord	0.664	0.336
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.663	0.337
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.663	0.337
C40-C41 Malignant neoplasms of bone and articular cartilage	0.663	0.337
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.663	0.337
T88.4 Failed or difficult intubation	0.662	0.338
K38 Other diseases of appendix	0.662	0.338
K65-K67 Diseases of peritoneum	0.662	0.338
E11.4 With neurological complications	0.661	0.339
G99 Other disorders of nervous system in diseases classified elsewhere	0.660	0.340
K63.2 Fistula of intestine	0.660	0.340
E66 Obesity	0.658	0.342
C44.6 Skin of upper limb, including shoulder	0.658	0.342
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.658	0.342
S22.3 Fracture of rib	0.657	0.343
H32 Chorioretinal disorders in diseases classified elsewhere	0.656	0.344
H31 Other disorders of choroid	0.656	0.344
H30 Chorioretinal inflammation	0.656	0.344
D03 Melanoma in situ	0.655	0.345
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.654	0.346
S69 Other and unspecified injuries of wrist and hand	0.654	0.346
S67 Crushing injury of wrist and hand	0.654	0.346
S65 Injury of blood vessels at wrist and hand level	0.654	0.346
B34 Viral infection of unspecified site	0.654	0.346
S22.4 Multiple fractures of ribs	0.653	0.347
H10-H13 Disorders of conjunctiva	0.652	0.347
E21.0 Primary hyperparathyroidism	0.652	0.348
E14.3 With ophthalmic complications	0.651	0.349
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.651	0.349
F99-F99 Unspecified mental disorder	0.651	0.349
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.651	0.349
F70-F79 Mental retardation	0.651	0.349
E05.8 Other thyrotoxicosis	0.650	0.350
E05.5 Thyroid crisis or storm	0.650	0.350
E05.4 Thyrotoxicosis factitia	0.650	0.350
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.650	0.350
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.650	0.350
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.650	0.350
T78.4 Allergy, unspecified	0.649	0.351
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.648	0.352
D67 Hereditary factor IX deficiency	0.647	0.353
D66 Hereditary factor VIII deficiency	0.647	0.353
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.647	0.353
T81.9 Unspecified complication of procedure	0.647	0.353
T81.7 Vascular complications following a procedure, not elsewhere classified	0.647	0.353
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.647	0.353
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.647	0.353
F80-F89 Disorders of psychological development	0.646	0.354
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.645	0.355
D61.9 Aplastic anaemia, unspecified	0.644	0.356
K42.9 Umbilical hernia without obstruction or gangrene	0.643	0.357
Q00-Q07 Congenital malformations of the nervous system	0.642	0.358
D04 Carcinoma in situ of skin	0.642	0.358
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.642	0.358
S20.8 Superficial injuries of other and unspecified parts of thorax	0.641	0.359
S62 Fracture at wrist and hand level	0.640	0.360
Q38-Q45 Other congenital malformations of the digestive system	0.640	0.360
K45 Other abdominal hernia	0.639	0.360
S42.9 Fracture of shoulder girdle, part unspecified	0.638	0.362
S42.8 Fracture of other parts of shoulder and upper arm	0.638	0.362
S42.7 Multiple fractures of clavicle, scapula and humerus	0.638	0.362
K44 Diaphragmatic hernia	0.638	0.362
K46 Unspecified abdominal hernia	0.637	0.363
H36.8 Other retinal disorders in diseases classified elsewhere	0.637	0.363
E16.9 Disorder of pancreatic internal secretion, unspecified	0.637	0.363
E16.8 Other specified disorders of pancreatic internal secretion	0.637	0.363
E16.4 Abnormal secretion of gastrin	0.637	0.363
E16.3 Increased secretion of glucagon	0.637	0.363
E16.1 Other hypoglycaemia	0.637	0.363
E16.0 Drug-induced hypoglycaemia without coma	0.637	0.363
S22.1 Multiple fractures of thoracic spine	0.636	0.364
C50.4 Upper-outer quadrant of breast	0.636	0.364
Q60-Q64 Congenital malformations of the urinary system	0.635	0.364
B99-B99 Other infectious diseases	0.635	0.365
B90-B94 Sequelae of infectious and parasitic diseases	0.635	0.365
B85-B89 Pediculosis, acariasis and other infestations	0.635	0.365
B65-B83 Helminthiases	0.635	0.365
B50-B64 Protozoal diseases	0.635	0.365
B20-B24 Human immunodeficiency virus [HIV] disease	0.635	0.365
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.635	0.365
A80-A89 Viral infections of the central nervous system	0.635	0.365
A75-A79 Rickettsioses	0.635	0.365
A70-A74 Other diseases caused by chlamydiae	0.635	0.365
A65-A69 Other spirochaetal diseases	0.635	0.365
A20-A28 Certain zoonotic bacterial diseases	0.635	0.365
A15-A19 Tuberculosis	0.635	0.365
E35 Disorders of endocrine glands in diseases classified elsewhere	0.634	0.366
E34 Other endocrine disorders	0.634	0.366
E32 Diseases of thymus	0.634	0.366
E31 Polyglandular dysfunction	0.634	0.366
E30 Disorders of puberty, not elsewhere classified	0.634	0.366
E29 Testicular dysfunction	0.634	0.366
E27 Other disorders of adrenal gland	0.634	0.366
E26 Hyperaldosteronism	0.634	0.366
E25 Adrenogenital disorders	0.634	0.366
E24 Cushing's syndrome	0.634	0.366
E23 Hypofunction and other disorders of pituitary gland	0.634	0.366
E22 Hyperfunction of pituitary gland	0.634	0.366
E20 Hypoparathyroidism	0.634	0.366
H47 Other disorders of optic [2nd] nerve and visual pathways	0.634	0.366
H46 Optic neuritis	0.633	0.366
S82 Fracture of lower leg, including ankle	0.633	0.367
G80-G83 Cerebral palsy and other paralytic syndromes	0.633	0.367
K62.7 Radiation proctitis	0.632	0.368
A04 Other bacterial intestinal infections	0.632	0.368
C43 Malignant melanoma of skin	0.631	0.369
E11.5 With peripheral circulatory complications	0.631	0.369
E07.8 Other specified disorders of thyroid	0.630	0.370
E07.1 Dyshormogenetic goitre	0.630	0.370
E07.0 Hypersecretion of calcitonin	0.630	0.370
K55.2 Angiodysplasia of colon	0.630	0.370
C67.9 Bladder, unspecified	0.630	0.370
T31 Burns classified according to extent of body surface involved	0.629	0.371
E11.8 With unspecified complications	0.628	0.371
E11.7 With multiple complications	0.628	0.371
E11.1 With ketoacidosis	0.628	0.371
E11.0 With coma	0.628	0.371
E11.2 With renal complications	0.628	0.372
K91.4 Colostomy and enterostomy malfunction	0.628	0.372
C44.2 Skin of ear and external auricular canal	0.628	0.372
F60 Specific personality disorders	0.626	0.374
E14.8 With unspecified complications	0.626	0.374
E14.7 With multiple complications	0.626	0.374
E14.6 With other specified complications	0.626	0.374
E14.5 With peripheral circulatory complications	0.626	0.374
E14.4 With neurological complications	0.626	0.374
E14.2 Withrenal complications	0.626	0.374
E14.1 With ketoacidosis	0.626	0.374
E14.0 With coma	0.626	0.374
T88.9 Complication of surgical and medical care, unspecified	0.625	0.374
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.625	0.374
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.625	0.374
T88.5 Other complications of anaesthesia	0.625	0.374
T88.3 Malignant hyperthermia due to anaesthesis	0.625	0.374
T88.2 Shock due to anaesthesia	0.625	0.374
T88.1 Other complications following immunisation, not elsewhere classified	0.625	0.374
T88.0 Infection following immunisation	0.625	0.374
D64.8 Other specified anaemias	0.625	0.374
D64.4 Congenital dyserythropoietic anaemia	0.625	0.374
D64.3 Other sideroblastic anaemias	0.625	0.374
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.625	0.374
D64.1 Secondary sideroblastic anaemia due to disease	0.625	0.374
D64.0 Hereditary sideroblastic anaemia	0.625	0.374
K64 Haemorrhoids and perianal venous thrombosis	0.625	0.375
S60.8 Other superficial injuries of wrist and hand	0.625	0.375
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.624	0.376
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.624	0.376
Q35-Q37 Cleft lip and cleft palate	0.624	0.376
Q30-Q34 Congenital malformations of the respiratory system	0.624	0.376
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.624	0.376
G93 Other disorders of brain	0.624	0.376
V20-V29 Motorcycle rider injured in transport accident	0.624	0.376
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.624	0.376
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.624	0.376
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.624	0.376
T83.2 Mechanical complication of graft of urinary organ	0.624	0.376
Y35-Y36 Legal intervention and operations of war	0.622	0.378
Y10-Y34 Event of undetermined intent	0.622	0.378
Y00-Y09 Assault	0.622	0.378
X85-X99 Assault	0.622	0.378
X58-X59 Accidental exposure to other and unspecified factors	0.622	0.378
X50-X57 Overexertion, travel and privation	0.622	0.378
X40-X49 Accidental poisoning by and exposure to noxious substances	0.622	0.378
X30-X39 Exposure to forces of nature	0.622	0.378
X10-X19 Contact with heat and hot substances	0.622	0.378
X00-X09 Exposure to smoke, fire and flames	0.622	0.378
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.622	0.378
W75-W84 Other accidental threats to breathing	0.622	0.378
W65-W74 Accidental drowning and submersion	0.622	0.378
W50-W64 Exposure to animate mechanical forces	0.622	0.378
V98-V99 Other and unspecified transport accidents	0.622	0.378
V95-V97 Air and space transport accidents	0.622	0.378
V90-V94 Water transport accidents	0.622	0.378
V80-V89 Other land transport accidents	0.622	0.378
V70-V79 Bus occupant injured in transport accident	0.622	0.378
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.622	0.378
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.622	0.378
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.622	0.378
V01-V09 Pedestrian injured in transport accident	0.622	0.378
T75 Effects of other external causes	0.619	0.381
T74 Maltreatment syndromes	0.619	0.381
T73 Effects of other deprivation	0.619	0.381
T70 Effects of air pressure and water pressure	0.619	0.381
T69 Other effects of reduced temperature	0.619	0.381
T67 Effects of heat and light	0.619	0.381
T71 Asphyxiation	0.619	0.381
T66 Unspecified effects of radiation	0.619	0.381
C66 Malignant neoplasm of ureter	0.618	0.382
Q27 Other congenital malformations of peripheral vascular system	0.617	0.382
H33.5 Other retinal detachments	0.617	0.383
S64.1 Injury of median nerve at wrist and hand level	0.617	0.383
K63.3 Ulcer of intestine	0.617	0.383
K77 Liver disorders in diseases classified elsewhere	0.616	0.384
K73 Chronic hepatitis, not elsewhere classified	0.616	0.384
K71 Toxic liver disease	0.616	0.384
S61.9 Open wound of wrist and hand, part unspecified	0.616	0.384
S22.0 Fracture of thoracic vertebra	0.615	0.385
X60-X84 Intentional self-harm	0.615	0.385
Q50-Q56 Congenital malformations of genital organs	0.615	0.385
D52 Folate deficiency anaemia	0.615	0.385
Y60-Y69 Misadventures to patients during surgical and medical care	0.614	0.386
K91.3 Postoperative intestinal obstruction	0.614	0.386
T14 Injury of unspecified body region	0.612	0.388
E50-E64 Other nutritional deficiencies	0.612	0.388
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.612	0.388
G96 Other disorders of central nervous system	0.612	0.388
G94 Other disorders of brain in diseases classified elsewhere	0.612	0.388
G90 Disorders of autonomic nervous system	0.612	0.388
G98 Other disorders of nervous system, not elsewhere classified	0.612	0.388
G92 Toxic encephalopathy	0.612	0.388
W20-W49 Exposure to inanimate mechanical forces	0.610	0.389
H33.0 Retinal detachment with retinal break	0.610	0.390
S68 Traumatic amputation of wrist and hand	0.610	0.390
C44.9 Malignant neoplasm of skin, unspecified	0.609	0.390
C44.8 Overlapping lesion of skin	0.609	0.390
A50-A64 Infections with a predominantly sexual mode of transmission	0.608	0.392
D80-D89 Certain disorders involving the immune mechanism	0.607	0.393
H34.8 Other retinal vascular occlusions	0.607	0.393
E28 Ovarian dysfunction	0.607	0.393
K63.0 Abscess of intestine	0.605	0.394
Y57 Other and unspecified drugs and medicaments	0.605	0.395
S42.30 Fracture of shaft of humerus (closed)	0.603	0.397
K62.2 Anal prolapse	0.601	0.398
S52.11 Fracture of upper end of radius (open)	0.601	0.399
D68.6 Other Thrombophilia	0.601	0.399
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.601	0.399
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.599	0.401
K70.4 Alcoholic hepatic failure	0.599	0.401
C51-C58 Malignant neoplasms of female genital organs	0.599	0.401
S81 Open wound of lower leg	0.598	0.402
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.597	0.403
D06.9 Cervix, unspecified	0.597	0.403
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.595	0.404
D09 Carcinoma in situ of other and unspecified sites	0.595	0.405
S52.61 Fracture of lower end of both ulna and radius (open)	0.595	0.405
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.595	0.405
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.595	0.405
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.595	0.405
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.595	0.405
S60.9 Superficial injury of wrist and hand, unspecified	0.594	0.406

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations