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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9837806
log Bayes Factor = 20.5678
Chromosome 3   position 161,064,585  (GRCh37) Explore rs9837806 on Ensembl!
Variant rs9837806 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
I10-I15 Hypertensive diseases
0.988 0.012 0.000
D10-D36 Benign neoplasms
0.986 0.014 0.000
I34 Nonrheumatic mitral valve disorders
0.984 0.016 0.000
M15-M19 Arthrosis
0.975 0.025 0.000
I73 Other peripheral vascular diseases
0.975 0.025 0.000
I10 Essential (primary) hypertension
0.975 0.025 0.000
I34.0 Mitral (valve) insufficiency
0.971 0.029 0.000
I21 Acute myocardial infarction
0.969 0.031 0.000
S80-S89 Injuries to the knee and lower leg
0.962 0.038 0.000
N17-N19 Renal failure
0.961 0.039 0.000
I73.9 Peripheral vascular disease, unspecified
0.960 0.040 0.000
E10-E14 Diabetes mellitus
0.958 0.042 0.000
N40-N51 Diseases of male genital organs
0.958 0.042 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.955 0.045 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.953 0.047 0.000
I49 Other cardiac arrhythmias
0.952 0.048 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.948 0.052 0.000
I21.9 Acute myocardial infarction, unspecified
0.947 0.053 0.000
I25.2 Old myocardial infarction
0.944 0.056 0.000
N18 Chronic renal failure
0.941 0.059 0.000
I71 Aortic aneurysm and dissection
0.940 0.060 0.000
M19 Other arthrosis
0.939 0.061 0.000
D23 Other benign neoplasms of skin
0.937 0.063 0.000
E78.0 Pure hypercholesterolaemia
0.929 0.071 0.000
Z13 Special screening examination for other diseases and disorders
0.927 0.073 0.000
Chapter XXI Factors influencing health status and contact with health services
0.926 0.074 0.000
N50 Other disorders of male genital organs
0.926 0.074 0.000
Z13.9 Special screening examination, unspecified
0.921 0.079 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.921 0.079 0.000
I50 Heart failure
0.919 0.081 0.000
M17 Gonarthrosis [arthrosis of knee]
0.919 0.081 0.000
E11 Non-insulin-dependent diabetes mellitus
0.918 0.082 0.000
M70-M79 Other soft tissue disorders
0.915 0.085 0.000
C15-C26 Malignant neoplasms of digestive organs
0.912 0.088 0.000
M17.9 Gonarthrosis, unspecified
0.912 0.088 0.000
I49.9 Cardiac arrhythmia, unspecified
0.910 0.090 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
M19.9 Arthrosis, unspecified
0.904 0.096 0.000
E83 Disorders of mineral metabolism
0.899 0.101 0.000
Chapter V Mental and behavioural disorders
0.899 0.101 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.894 0.106 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.890 0.110 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.888 0.112 0.000
N25-N29 Other disorders of kidney and ureter
0.885 0.114 0.000
C60-C63 Malignant neoplasms of male genital organs
0.884 0.116 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.882 0.118 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.882 0.118 0.000
S20-S29 Injuries to the thorax
0.879 0.121 0.000
E11.3 With ophthalmic complications
0.878 0.122 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.878 0.122 0.000
I72 Other aneurysm
0.877 0.123 0.000
M05-M14 Inflammatory polyarthropathies
0.877 0.123 0.000
E87.5 Hyperkalaemia
0.870 0.130 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.868 0.132 0.000
Chapter VI Diseases of the nervous system
0.868 0.132 0.000
Chapter VII Diseases of the eye and adnexa
0.868 0.132 0.000
D12.4 Descending colon
0.867 0.133 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.864 0.136 0.000
I25.1 Atherosclerotic heart disease
0.863 0.137 0.000
N18.9 Chronic renal failure, unspecified
0.862 0.138 0.000
N50.8 Other specified disorders of male genital organs
0.862 0.138 0.000
I05-I09 Chronic rheumatic heart diseases
0.860 0.140 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.859 0.141 0.000
D34 Benign neoplasm of thyroid gland
0.858 0.142 0.000
E65-E68 Obesity and other hyperalimentation
0.858 0.142 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.858 0.142 0.000
N43 Hydrocele and spermatocele
0.857 0.143 0.000
T81 Complications of procedures, not elsewhere classified
0.855 0.145 0.000
S70-S79 Injuries to the hip and thigh
0.846 0.154 0.000
F10.0 Acute intoxication
0.843 0.157 0.000
I44 Atrioventricular and left bundle-branch block
0.842 0.158 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.842 0.158 0.000
N10-N16 Renal tubulo-interstitial diseases
0.841 0.159 0.000
S81 Open wound of lower leg
0.841 0.159 0.000
I50.1 Left ventricular failure
0.839 0.161 0.000
M20-M25 Other joint disorders
0.839 0.161 0.000
E00-E07 Disorders of thyroid gland
0.837 0.163 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.837 0.163 0.000
Chapter XI Diseases of the digestive system
0.836 0.164 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.835 0.165 0.000
N50.1 Vascular disorders of male genital organs
0.833 0.167 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.830 0.170 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.830 0.170 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.830 0.170 0.000
D12.3 Transverse colon
0.829 0.171 0.000
Chapter XX External causes of morbidity and mortality
0.828 0.172 0.000
Chapter I Certain infectious and parasitic diseases
0.825 0.175 0.000
F10.2 Dependence syndrome
0.825 0.175 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.823 0.177 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.822 0.178 0.000
T82.1 Mechanical complication of cardiac electronic device
0.822 0.178 0.000
I35 Nonrheumatic aortic valve disorders
0.822 0.178 0.000
I42 Cardiomyopathy
0.821 0.179 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.821 0.179 0.000
N18.5 Chronic kidney disease, stage 5
0.818 0.182 0.000
G56 Mononeuropathies of upper limb
0.818 0.182 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.817 0.183 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.815 0.185 0.000
N41 Inflammatory diseases of prostate
0.814 0.186 0.000
M50-M54 Other dorsopathies
0.814 0.186 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.814 0.186 0.000
K70-K77 Diseases of liver
0.810 0.190 0.000
D23.5 Skin of trunk
0.809 0.191 0.000
I25.5 Ischaemic cardiomyopathy
0.809 0.191 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
I74 Arterial embolism and thrombosis
0.807 0.193 0.000
M80-M85 Disorders of bone density and structure
0.806 0.194 0.000
I49.4 Other and unspecified premature depolarisation
0.806 0.194 0.000
S40-S49 Injuries to the shoulder and upper arm
0.805 0.195 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.804 0.196 0.000
E50-E64 Other nutritional deficiencies
0.803 0.197 0.000
D23.7 Skin of lower limb, including hip
0.803 0.197 0.000
D00-D09 In situ neoplasms
0.802 0.198 0.000
M06 Other rheumatoid arthritis
0.800 0.200 0.000
N00-N08 Glomerular diseases
0.800 0.200 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.800 0.200 0.000
H30-H36 Disorders of choroid and retina
0.799 0.201 0.000
C64-C68 Malignant neoplasms of urinary tract
0.799 0.201 0.000
N18.4 Chronic kidney disease, stage 4
0.798 0.202 0.000
K70 Alcoholic liver disease
0.798 0.202 0.000
N13 Obstructive and reflux uropathy
0.794 0.206 0.000
I77 Other disorders of arteries and arterioles
0.794 0.206 0.000
I12 Hypertensive renal disease
0.793 0.207 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.792 0.208 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.792 0.208 0.000
C44 Other malignant neoplasms of skin
0.792 0.208 0.000
S80 Superficial injury of lower leg
0.791 0.209 0.000
I72.4 Aneurysm of artery of lower extremity
0.791 0.209 0.000
E87.2 Acidosis
0.790 0.209 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.790 0.210 0.000
C15 Malignant neoplasm of oesophagus
0.790 0.210 0.000
G56.0 Carpal tunnel syndrome
0.790 0.210 0.000
S82 Fracture of lower leg, including ankle
0.788 0.212 0.000
D45 Polycythaemia vera
0.785 0.215 0.000
N43.3 Hydrocele, unspecified
0.785 0.215 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.783 0.217 0.000
I37 Pulmonary valve disorders
0.781 0.219 0.000
D12.2 Ascending colon
0.781 0.219 0.000
S00-S09 Injuries to the head
0.779 0.221 0.000
D32 Benign neoplasm of meninges
0.775 0.225 0.000
E10 Insulin-dependent diabetes mellitus
0.774 0.226 0.000
I30 Acute pericarditis
0.771 0.229 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.770 0.230 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.769 0.231 0.000
D23.3 Skin of other and unspecified parts of face
0.769 0.231 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.769 0.231 0.000
D12.7 Rectosigmoid junction
0.768 0.232 0.000
I49.0 Ventricular fibrillation and flutter
0.766 0.234 0.000
I34.1 Mitral (valve) prolapse
0.765 0.235 0.000
M60-M63 Disorders of muscles
0.764 0.235 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.764 0.236 0.000
D10 Benign neoplasm of mouth and pharynx
0.763 0.237 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.763 0.237 0.000
T86 Failure and rejection of transplanted organs and tissues
0.762 0.238 0.000
M22 Disorders of patella
0.762 0.238 0.000
D12.5 Sigmoid colon
0.762 0.238 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.761 0.239 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.761 0.239 0.000
E87.3 Alkalosis
0.760 0.240 0.000
H36 Retinal disorders in diseases classified elsewhere
0.759 0.241 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.759 0.241 0.000
E87.7 Fluid overload
0.759 0.241 0.000
C25 Malignant neoplasm of pancreas
0.758 0.242 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.758 0.242 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.757 0.243 0.000
I20 Angina pectoris
0.756 0.244 0.000
E66 Obesity
0.756 0.244 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.756 0.244 0.000
T79-T79 Certain early complications of trauma
0.755 0.244 0.000
S20 Superficial injury of thorax
0.755 0.245 0.000
K70.9 Alcoholic liver disease, unspecified
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.754 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.752 0.248 0.000
C18 Malignant neoplasm of colon
0.752 0.248 0.000
Z04 Examination and observation for other reasons
0.751 0.249 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.751 0.249 0.000
I50.0 Congestive heart failure
0.750 0.250 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
W00-W19 Falls
0.748 0.252 0.000
E78.2 Mixed hyperlipidaemia
0.746 0.254 0.000
N42 Other disorders of prostate
0.746 0.254 0.000
E83.4 Disorders of magnesium metabolism
0.746 0.254 0.000
C62 Malignant neoplasm of testis
0.744 0.256 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.743 0.257 0.000
M06.9 Rheumatoid arthritis, unspecified
0.742 0.258 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.741 0.259 0.000
D23.9 Skin, unspecified
0.739 0.260 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.739 0.261 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.738 0.262 0.000
C61 Malignant neoplasm of prostate
0.737 0.263 0.000
E11.9 Without complications
0.736 0.264 0.000
M19.0 Primary arthrosis of other joints
0.735 0.265 0.000
M91-M94 Chondropathies
0.735 0.265 0.000
N18.2 Chronic kidney disease, stage 2
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
K08 Other disorders of teeth and supporting structures
0.733 0.267 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.733 0.267 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.733 0.267 0.000
E83.1 Disorders of iron metabolism
0.732 0.268 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.731 0.269 0.000
H36.0 Diabetic retinopathy
0.731 0.269 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.730 0.270 0.000
N20-N23 Urolithiasis
0.730 0.270 0.000
I33 Acute and subacute endocarditis
0.730 0.270 0.000
N45 Orchitis and epididymitis
0.728 0.272 0.000
C15.9 Oesophagus, unspecified
0.726 0.274 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.725 0.275 0.000
M54 Dorsalgia
0.724 0.275 0.000
S81.8 Open wound of other parts of lower leg
0.724 0.276 0.000
I44.1 Atrioventricular block, second degree
0.723 0.277 0.000
S50-S59 Injuries to the elbow and forearm
0.723 0.277 0.000
D23.1 Skin of eyelid, including canthus
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.277 0.000
D18 Haemangioma and lymphangioma, any site
0.722 0.278 0.000
E04 Other non-toxic goitre
0.720 0.280 0.000
I71.0 Dissection of aorta [any part]
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I08 Multiple valve diseases
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
S89 Other and unspecified injuries of lower leg
0.716 0.284 0.000
I35.1 Aortic (valve) insufficiency
0.716 0.284 0.000
E66.9 Obesity, unspecified
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
I38 Endocarditis, valve unspecified
0.715 0.285 0.000
I70 Atherosclerosis
0.714 0.286 0.000
E88 Other metabolic disorders
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
E86 Volume depletion
0.714 0.286 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
E83.3 Disorders of phosphorus metabolism
0.712 0.288 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.711 0.289 0.000
C91 Lymphoid leukaemia
0.710 0.290 0.000
I20.9 Angina pectoris, unspecified
0.710 0.290 0.000
M79.1 Myalgia
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.708 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.708 0.291 0.000
G57 Mononeuropathies of lower limb
0.708 0.292 0.000
I15 Secondary hypertension
0.708 0.292 0.000
I13 Hypertensive heart and renal disease
0.708 0.292 0.000
I11 Hypertensive heart disease
0.708 0.292 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.708 0.292 0.000
D31 Benign neoplasm of eye and adnexa
0.707 0.293 0.000
D30 Benign neoplasm of urinary organs
0.707 0.293 0.000
D29 Benign neoplasm of male genital organs
0.707 0.293 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.707 0.293 0.000
D26 Other benign neoplasms of uterus
0.707 0.293 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.707 0.293 0.000
D19 Benign neoplasm of mesothelial tissue
0.707 0.293 0.000
D16 Benign neoplasm of bone and articular cartilage
0.707 0.293 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.707 0.293 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.707 0.293 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.707 0.293 0.000
M79.6 Pain in limb
0.707 0.293 0.000
M13 Other arthritis
0.706 0.294 0.000
E11.2 With renal complications
0.706 0.294 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.706 0.294 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.706 0.294 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.706 0.294 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.706 0.294 0.000
C16 Malignant neoplasm of stomach
0.706 0.294 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.294 0.000
M40-M43 Deforming dorsopathies
0.705 0.294 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.705 0.295 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.704 0.296 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.704 0.296 0.000
D12.8 Rectum
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.704 0.296 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.703 0.297 0.000
K08.3 Retained dental root
0.703 0.297 0.000
K70.3 Alcoholic cirrhosis of liver
0.703 0.297 0.000
S72 Fracture of femur
0.703 0.297 0.000
B95-B98 Bacterial, viral and other infectious agents
0.702 0.298 0.000
N18.3 Chronic kidney disease, stage 3
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
S32 Fracture of lumbar spine and pelvis
0.700 0.300 0.000
I51 Complications and ill-defined descriptions of heart disease
0.699 0.301 0.000
M15 Polyarthrosis
0.699 0.301 0.000
I73.8 Other specified peripheral vascular diseases
0.699 0.301 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.699 0.301 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.696 0.304 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.696 0.304 0.000
M79.0 Rheumatism, unspecified
0.695 0.305 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.695 0.305 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.695 0.305 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.695 0.305 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.695 0.305 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.694 0.306 0.000
D12.0 Caecum
0.693 0.307 0.000
I44.7 Left bundle-branch block, unspecified
0.693 0.307 0.000
G50 Disorders of trigeminal nerve
0.692 0.308 0.000
M21 Other acquired deformities of limbs
0.691 0.309 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.691 0.309 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.690 0.310 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.690 0.310 0.000
D36 Benign neoplasm of other and unspecified sites
0.690 0.310 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.690 0.310 0.000
S88 Traumatic amputation of lower leg
0.689 0.310 0.000
S87 Crushing injury of lower leg
0.689 0.310 0.000
S86 Injury of muscle and tendon at lower leg level
0.689 0.310 0.000
S85 Injury of blood vessels at lower leg level
0.689 0.310 0.000
S84 Injury of nerves at lower leg level
0.689 0.310 0.000
N19 Unspecified renal failure
0.689 0.311 0.000
N41.0 Acute prostatitis
0.687 0.313 0.000
E12 Malnutrition-related diabetes mellitus
0.687 0.313 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.687 0.313 0.000
N46 Male infertility
0.687 0.313 0.000
N44 Torsion of testis
0.687 0.313 0.000
D04 Carcinoma in situ of skin
0.686 0.314 0.000
C18.9 Colon, unspecified
0.686 0.314 0.000
N17 Acute renal failure
0.685 0.315 0.000
D12.9 Anus and anal canal
0.685 0.315 0.000
D12.1 Appendix
0.685 0.315 0.000
N26 Unspecified contracted kidney
0.684 0.316 0.000
M45-M49 Spondylopathies
0.684 0.316 0.000
S42 Fracture of shoulder and upper arm
0.684 0.316 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.683 0.316 0.000
E87.4 Mixed disorder of acid-base balance
0.683 0.316 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.683 0.317 0.000
I49.2 Junctional premature depolarisation
0.682 0.318 0.000
I49.1 Atrial premature depolarisation
0.682 0.318 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.682 0.318 0.000
M71 Other bursopathies
0.680 0.320 0.000
I77.1 Stricture of artery
0.680 0.320 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.680 0.320 0.000
E78.8 Other disorders of lipoprotein metabolism
0.680 0.320 0.000
E78.6 Lipoprotein deficiency
0.680 0.320 0.000
E78.4 Other hyperlipidaemia
0.680 0.320 0.000
E78.3 Hyperchylomicronaemia
0.680 0.320 0.000
E78.1 Pure hyperglyceridaemia
0.680 0.320 0.000
D13.0 Oesophagus
0.679 0.321 0.000
I73.0 Raynaud's syndrome
0.679 0.321 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.679 0.321 0.000
S82.4 Fracture of fibula alone
0.678 0.322 0.000
T58 Toxic effect of carbon monoxide
0.677 0.323 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
N18.8 Other chronic renal failure
0.675 0.325 0.000
N18.1 Chronic kidney disease, stage 1
0.675 0.325 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.674 0.326 0.000
E11.4 With neurological complications
0.674 0.326 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.674 0.326 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.674 0.326 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.674 0.326 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.674 0.326 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.674 0.326 0.000
M19.8 Other specified arthrosis
0.673 0.327 0.000
M19.2 Other secondary arthrosis
0.673 0.327 0.000
M19.1 Posttraumatic arthrosis of other joints
0.673 0.327 0.000
S00 Superficial injury of head
0.673 0.327 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.672 0.328 0.000
D23.2 Skin of ear and external auricular canal
0.672 0.328 0.000
D23.0 Skin of lip
0.672 0.328 0.000
E87.0 Hyperosmolality and hypernatraemia
0.671 0.329 0.000
D22 Melanocytic naevi
0.671 0.329 0.000
K40-K46 Hernia
0.670 0.330 0.000
M86-M90 Other osteopathies
0.670 0.330 0.000
M79.8 Other specified soft tissue disorders
0.670 0.330 0.000
T17 Foreign body in respiratory tract
0.670 0.330 0.000
C81 Hodgkin's disease
0.669 0.331 0.000
Chapter VIII Diseases of the ear and mastoid process
0.669 0.331 0.000
S80.9 Superficial injury of lower leg, unspecified
0.669 0.331 0.000
M22.2 Patellofemoral disorders
0.668 0.332 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.668 0.332 0.000
F99-F99 Unspecified mental disorder
0.666 0.334 0.000
I22 Subsequent myocardial infarction
0.665 0.335 0.000
M54.2 Cervicalgia
0.665 0.335 0.000
C25.9 Pancreas, unspecified
0.665 0.335 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.664 0.336 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.664 0.336 0.000
Z13.5 Special screening examination for eye and ear disorders
0.664 0.336 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.664 0.336 0.000
Z13.2 Special screening examination for nutritional disorders
0.664 0.336 0.000
N50.9 Disorder of male genital organs, unspecified
0.664 0.336 0.000
N50.0 Atrophy of testis
0.664 0.336 0.000
E06 Thyroiditis
0.664 0.336 0.000
C69 Malignant neoplasm of eye and adnexa
0.663 0.337 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.663 0.337 0.000
N18.0 End-stage renal disease
0.663 0.337 0.000
I05 Rheumatic mitral valve diseases
0.661 0.338 0.000
Z10 Routine general health check-up of defined subpopulation
0.660 0.339 0.000
C44.4 Skin of scalp and neck
0.660 0.340 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.660 0.340 0.000
S79 Other and unspecified injuries of hip and thigh
0.660 0.340 0.000
D35.0 Adrenal gland
0.660 0.340 0.000
K35-K38 Diseases of appendix
0.660 0.340 0.000
M17.5 Other secondary gonarthrosis
0.659 0.341 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.659 0.341 0.000
M17.3 Other posttraumatic gonarthrosis
0.659 0.341 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.659 0.341 0.000
I12.0 Hypertensive renal disease with renal failure
0.659 0.341 0.000
E83.5 Disorders of calcium metabolism
0.659 0.341 0.000
E11.8 With unspecified complications
0.658 0.342 0.000
E11.7 With multiple complications
0.658 0.342 0.000
E11.6 With other specified complications
0.658 0.342 0.000
E11.1 With ketoacidosis
0.658 0.342 0.000
E11.0 With coma
0.658 0.342 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.658 0.342 0.000
M76 Enthesopathies of lower limb, excluding foot
0.656 0.344 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.656 0.344 0.000
E61 Deficiency of other nutrient elements
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.654 0.346 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.654 0.346 0.000
C21 Malignant neoplasm of anus and anal canal
0.654 0.346 0.000
C17 Malignant neoplasm of small intestine
0.654 0.346 0.000
C23 Malignant neoplasm of gallbladder
0.654 0.346 0.000
S81.9 Open wound of lower leg, part unspecified
0.654 0.346 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.654 0.346 0.000
C51-C58 Malignant neoplasms of female genital organs
0.654 0.346 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.653 0.347 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.653 0.347 0.000
H43-H45 Disorders of vitreous body and globe
0.652 0.348 0.000
Z73 Problems related to life-management difficulty
0.652 0.348 0.000
S82.5 Fracture of medial malleolus
0.651 0.349 0.000
C44.2 Skin of ear and external auricular canal
0.651 0.349 0.000
E14 Unspecified diabetes mellitus
0.651 0.349 0.000
K65-K67 Diseases of peritoneum
0.651 0.349 0.000
I07 Rheumatic tricuspid valve diseases
0.650 0.350 0.000
H55-H59 Other disorders of eye and adnexa
0.650 0.350 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.649 0.351 0.000
Z13.1 Special screening examination for diabetes mellitus
0.649 0.351 0.000
M79.7 Fibromyalgia
0.649 0.351 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.648 0.352 0.000
I49.3 Ventricular premature depolarisation
0.648 0.352 0.000
B35-B49 Mycoses
0.648 0.352 0.000
S27 Injury of other and unspecified intrathoracic organs
0.647 0.353 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.647 0.353 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.646 0.354 0.000
D13.2 Duodenum
0.646 0.354 0.000
N48 Other disorders of penis
0.646 0.354 0.000
W19 Unspecified fall
0.646 0.354 0.000
G56.8 Other mononeuropathies of upper limb
0.646 0.354 0.000
C79 Secondary malignant neoplasm of other sites
0.645 0.355 0.000
T63 Toxic effect of contact with venomous animals
0.645 0.355 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.644 0.355 0.000
E83.8 Other disorders of mineral metabolism
0.644 0.355 0.000
E83.2 Disorders of zinc metabolism
0.644 0.355 0.000
E83.0 Disorders of copper metabolism
0.644 0.355 0.000
N13.8 Other obstructive and reflux uropathy
0.644 0.356 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.644 0.356 0.000
F80-F89 Disorders of psychological development
0.644 0.356 0.000
F70-F79 Mental retardation
0.644 0.356 0.000
F60-F69 Disorders of adult personality and behaviour
0.644 0.356 0.000
I42.9 Cardiomyopathy, unspecified
0.644 0.356 0.000
C62.9 Testis, unspecified
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
N28.8 Other specified disorders of kidney and ureter
0.643 0.357 0.000
Q60-Q64 Congenital malformations of the urinary system
0.642 0.358 0.000
M72 Fibroblastic disorders
0.642 0.358 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.642 0.358 0.000
I49.8 Other specified cardiac arrhythmias
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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