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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11134797
log Bayes Factor = 12.6738
Chromosome 5   position 172,860,596  (GRCh37) Explore rs11134797 on Ensembl!
Variant rs11134797 is part of Cluster X0209

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
E11 Non-insulin-dependent diabetes mellitus
0.983 0.017 0.000
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
A30-A49 Other bacterial diseases
0.980 0.020 0.000
E20-E35 Disorders of other endocrine glands
0.979 0.021 0.000
M80-M85 Disorders of bone density and structure
0.977 0.023 0.000
M45-M49 Spondylopathies
0.973 0.027 0.000
S70-S79 Injuries to the hip and thigh
0.972 0.028 0.000
Chapter VIII Diseases of the ear and mastoid process
0.969 0.031 0.000
E11.9 Without complications
0.967 0.033 0.000
E14 Unspecified diabetes mellitus
0.963 0.037 0.000
A41 Other septicaemia
0.961 0.039 0.000
Chapter II Neoplasms
0.960 0.040 0.000
E10 Insulin-dependent diabetes mellitus
0.951 0.049 0.000
E27 Other disorders of adrenal gland
0.950 0.050 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.950 0.050 0.000
S72 Fracture of femur
0.948 0.052 0.000
E14.9 Without complications
0.948 0.052 0.000
M47 Spondylosis
0.944 0.056 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.943 0.057 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.943 0.057 0.000
E00-E07 Disorders of thyroid gland
0.943 0.057 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.940 0.060 0.000
M47.8 Other spondylosis
0.937 0.063 0.000
M06 Other rheumatoid arthritis
0.937 0.063 0.000
S72.0 Fracture of neck of femur
0.929 0.071 0.000
M47.82 Other spondylosis (Cervical region)
0.928 0.072 0.000
S50-S59 Injuries to the elbow and forearm
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.923 0.077 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.917 0.083 0.000
S72.00 Fracture of neck of femur (closed)
0.915 0.085 0.000
S90-S99 Injuries to the ankle and foot
0.915 0.085 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.911 0.089 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.910 0.090 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.909 0.091 0.000
D10-D36 Benign neoplasms
0.909 0.091 0.000
Chapter V Mental and behavioural disorders
0.908 0.092 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.906 0.094 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.901 0.099 0.000
S00-S09 Injuries to the head
0.900 0.100 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.897 0.103 0.000
E10.9 Without complications
0.892 0.108 0.000
Z43 Attention to artificial openings
0.891 0.109 0.000
C77.1 Intrathoracic lymph nodes
0.889 0.111 0.000
M05 Seropositive rheumatoid arthritis
0.888 0.112 0.000
M06.9 Rheumatoid arthritis, unspecified
0.888 0.112 0.000
H60-H62 Diseases of external ear
0.886 0.114 0.000
H65-H75 Diseases of middle ear and mastoid
0.886 0.114 0.000
M81 Osteoporosis without pathological fracture
0.885 0.115 0.000
E27.1 Primary adrenocortical insufficiency
0.877 0.123 0.000
Z45 Adjustment and management of implanted device
0.876 0.124 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.876 0.124 0.000
Z83 Family history of other specific disorders
0.871 0.129 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.870 0.130 0.000
D12.2 Ascending colon
0.869 0.131 0.000
M86-M90 Other osteopathies
0.869 0.131 0.000
D12.4 Descending colon
0.860 0.140 0.000
M82 Osteoporosis in diseases classified elsewhere
0.860 0.140 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.859 0.141 0.000
S52 Fracture of forearm
0.858 0.142 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.856 0.144 0.000
Z83.7 Family history of diseases of the digestive system
0.853 0.147 0.000
Chapter VII Diseases of the eye and adnexa
0.851 0.149 0.000
M84 Disorders of continuity of bone
0.851 0.149 0.000
Chapter VI Diseases of the nervous system
0.850 0.150 0.000
M70-M79 Other soft tissue disorders
0.849 0.151 0.000
S92 Fracture of foot, except ankle
0.848 0.152 0.000
Z94 Transplanted organ and tissue status
0.845 0.155 0.000
Z22 Carrier of infectious disease
0.845 0.155 0.000
T93 Sequelae of injuries of lower limb
0.843 0.157 0.000
Z29 Need for other prophylactic measures
0.841 0.159 0.000
Z43.3 Attention to colostomy
0.840 0.160 0.000
M46 Other inflammatory spondylopathies
0.840 0.160 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.839 0.161 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.836 0.164 0.000
E70-E90 Metabolic disorders
0.835 0.165 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.834 0.166 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.833 0.167 0.000
E22 Hyperfunction of pituitary gland
0.832 0.168 0.000
E04 Other non-toxic goitre
0.831 0.168 0.000
Z86 Personal history of certain other diseases
0.830 0.170 0.000
G40-G47 Episodic and paroxysmal disorders
0.826 0.174 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.825 0.175 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.823 0.177 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.821 0.179 0.000
Q60-Q64 Congenital malformations of the urinary system
0.819 0.181 0.000
H90-H95 Other disorders of ear
0.818 0.182 0.000
Z83.5 Family history of eye and ear disorders
0.817 0.183 0.000
S10-S19 Injuries to the neck
0.817 0.183 0.000
A49 Bacterial infection of unspecified site
0.815 0.185 0.000
S32 Fracture of lumbar spine and pelvis
0.815 0.185 0.000
Z86.0 Personal history of other neoplasms
0.814 0.186 0.000
Z72 Problems related to lifestyle
0.814 0.186 0.000
Z80 Family history of malignant neoplasm
0.812 0.188 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.811 0.189 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.809 0.191 0.000
H72 Perforation of tympanic membrane
0.808 0.192 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.807 0.193 0.000
M06.3 Rheumatoid nodule
0.801 0.199 0.000
M81.9 Osteoporosis, unspecified
0.801 0.199 0.000
C77.0 Lymph nodes of head, face and neck
0.800 0.200 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.799 0.201 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.796 0.204 0.000
B35-B49 Mycoses
0.795 0.205 0.000
S92.3 Fracture of metatarsal bone
0.794 0.206 0.000
E26 Hyperaldosteronism
0.793 0.207 0.000
D12.3 Transverse colon
0.792 0.208 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.789 0.211 0.000
M47.86 Other spondylosis (Lumbar region)
0.788 0.212 0.000
A00-A09 Intestinal infectious diseases
0.785 0.215 0.000
D00-D09 In situ neoplasms
0.785 0.215 0.000
Z41 Procedures for purposes other than remedying health state
0.784 0.216 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.780 0.220 0.000
Z49 Care involving dialysis
0.779 0.221 0.000
W50-W64 Exposure to animate mechanical forces
0.777 0.223 0.000
Z94.0 Kidney transplant status
0.777 0.223 0.000
M82.1 Osteoporosis in endocrine disorders
0.776 0.224 0.000
C78.0 Secondary malignant neoplasm of lung
0.775 0.225 0.000
M47.89 Other spondylosis (Site unspecified)
0.774 0.226 0.000
M13 Other arthritis
0.774 0.226 0.000
E11.3 With ophthalmic complications
0.773 0.227 0.000
W20-W49 Exposure to inanimate mechanical forces
0.771 0.229 0.000
H60 Otitis externa
0.770 0.230 0.000
Z45.2 Adjustment and management of vascular access device
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.769 0.231 0.000
K86 Other diseases of pancreas
0.769 0.231 0.000
Chapter XI Diseases of the digestive system
0.767 0.233 0.000
Z45.8 Adjustment and management of other implanted devices
0.766 0.234 0.000
B15-B19 Viral hepatitis
0.765 0.235 0.000
Z22.3 Carrier of other specified bacterial diseases
0.765 0.235 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.760 0.240 0.000
C77.5 Intrapelvic lymph nodes
0.759 0.241 0.000
H61 Other disorders of external ear
0.759 0.241 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.758 0.242 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.758 0.242 0.000
E11.6 With other specified complications
0.757 0.243 0.000
Chapter XXII Codes for special purposes
0.757 0.243 0.000
Q80-Q89 Other congenital malformations
0.757 0.243 0.000
E11.4 With neurological complications
0.756 0.244 0.000
Z43.8 Attention to other artificial openings
0.755 0.245 0.000
S92.30 Fracture of metatarsal bone (closed)
0.755 0.245 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.754 0.245 0.000
M07 Psoriatic and enteropathic arthropathies
0.754 0.246 0.000
E27.2 Addisonian crisis
0.753 0.247 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.753 0.247 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.752 0.248 0.000
D50-D53 Nutritional anaemias
0.751 0.249 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.749 0.251 0.000
Z29.1 Prophylactic immunotherapy
0.749 0.251 0.000
E34 Other endocrine disorders
0.749 0.251 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.748 0.252 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.748 0.252 0.000
V10-V19 Pedal cyclist injured in transport accident
0.748 0.252 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.747 0.252 0.000
S02 Fracture of skull and facial bones
0.747 0.253 0.000
T91 Sequelae of injuries of neck and trunk
0.747 0.253 0.000
E10.3 With ophthalmic complications
0.746 0.254 0.000
E04.1 Non-toxic single thyroid nodule
0.746 0.254 0.000
H90 Conductive and sensorineural hearing loss
0.745 0.255 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.744 0.256 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.744 0.256 0.000
S70 Superficial injury of hip and thigh
0.743 0.257 0.000
A40 Streptococcal septicaemia
0.742 0.258 0.000
C15-C26 Malignant neoplasms of digestive organs
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.740 0.260 0.000
Q50-Q56 Congenital malformations of genital organs
0.740 0.260 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.738 0.262 0.000
T92 Sequelae of injuries of upper limb
0.737 0.263 0.000
S60-S69 Injuries to the wrist and hand
0.737 0.263 0.000
Z72.1 Alcohol use
0.736 0.264 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.735 0.265 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.734 0.266 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.734 0.266 0.000
Z89 Acquired absence of limb
0.733 0.267 0.000
Q00-Q07 Congenital malformations of the nervous system
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.268 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.732 0.268 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.731 0.269 0.000
M90 Osteopathies in diseases classified elsewhere
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.729 0.271 0.000
Y40 Systemic antibiotics
0.729 0.271 0.000
M85 Other disorders of bone density and structure
0.728 0.272 0.000
K86.8 Other specified diseases of pancreas
0.728 0.272 0.000
E11.5 With peripheral circulatory complications
0.728 0.272 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.727 0.273 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.725 0.275 0.000
E27.8 Other specified disorders of adrenal gland
0.725 0.275 0.000
Q61 Cystic kidney disease
0.724 0.276 0.000
D24 Benign neoplasm of breast
0.724 0.276 0.000
S56 Injury of muscle and tendon at forearm level
0.722 0.278 0.000
H55-H59 Other disorders of eye and adnexa
0.721 0.279 0.000
Z52 Donors of organs and tissues
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
A49.8 Other bacterial infections of unspecified site
0.720 0.280 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.719 0.281 0.000
S09 Other and unspecified injuries of head
0.719 0.281 0.000
D12.5 Sigmoid colon
0.719 0.281 0.000
E27.9 Disorder of adrenal gland, unspecified
0.718 0.282 0.000
D12.6 Colon, unspecified
0.718 0.282 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.717 0.283 0.000
Z29.8 Other specified prophylactic measures
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
S52.0 Fracture of upper end of ulna
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
C80 Malignant neoplasm without specification of site
0.714 0.286 0.000
S72.3 Fracture of shaft of femur
0.714 0.286 0.000
E24 Cushing's syndrome
0.714 0.286 0.000
S52.6 Fracture of lower end of both ulna and radius
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
H74 Other disorders of middle ear and mastoid
0.711 0.289 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.711 0.289 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.711 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.711 0.289 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.289 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.711 0.289 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.710 0.290 0.000
A41.8 Other specified septicaemia
0.710 0.290 0.000
S72.2 Subtrochanteric fracture
0.709 0.290 0.000
E10.4 With neurological complications
0.709 0.291 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.708 0.292 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.707 0.292 0.000
M10 Gout
0.707 0.293 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.707 0.293 0.000
H71 Cholesteatoma of middle ear
0.706 0.293 0.000
E05.9 Thyrotoxicosis, unspecified
0.706 0.294 0.000
E83 Disorders of mineral metabolism
0.706 0.294 0.000
Z40 Prophylactic surgery
0.705 0.295 0.000
E11.8 With unspecified complications
0.705 0.295 0.000
E11.7 With multiple complications
0.705 0.295 0.000
E11.0 With coma
0.705 0.295 0.000
E10.2 With renal complications
0.704 0.295 0.000
M14 Arthropathies in other diseases classified elsewhere
0.704 0.296 0.000
M12 Other specific arthropathies
0.704 0.296 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
S91 Open wound of ankle and foot
0.704 0.296 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
A48 Other bacterial diseases, not elsewhere classified
0.702 0.297 0.000
A44 Bartonellosis
0.702 0.297 0.000
A43 Nocardiosis
0.702 0.297 0.000
A42 Actinomycosis
0.702 0.297 0.000
A39 Meningococcal infection
0.702 0.297 0.000
A37 Whooping cough
0.702 0.297 0.000
A36 Diphtheria
0.702 0.297 0.000
A32 Listeriosis
0.702 0.297 0.000
A31 Infection due to other mycobacteria
0.702 0.297 0.000
A30 Leprosy [Hansen's disease]
0.702 0.297 0.000
A46 Erysipelas
0.702 0.297 0.000
A38 Scarlet fever
0.702 0.297 0.000
A35 Other tetanus
0.702 0.297 0.000
A34 Obstetrical tetanus
0.702 0.297 0.000
A33 Tetanus neonatorum
0.702 0.297 0.000
H25-H28 Disorders of lens
0.702 0.298 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.702 0.298 0.000
E32 Diseases of thymus
0.702 0.298 0.000
E31 Polyglandular dysfunction
0.702 0.298 0.000
E30 Disorders of puberty, not elsewhere classified
0.702 0.298 0.000
E25 Adrenogenital disorders
0.702 0.298 0.000
E20 Hypoparathyroidism
0.702 0.298 0.000
E10.1 With ketoacidosis
0.701 0.298 0.000
M83 Adult osteomalacia
0.700 0.299 0.000
D51 Vitamin B12 deficiency anaemia
0.700 0.300 0.000
H72.8 Other perforations of tympanic membrane
0.698 0.301 0.000
F41 Other anxiety disorders
0.699 0.301 0.000
E88 Other metabolic disorders
0.698 0.302 0.000
E11.1 With ketoacidosis
0.697 0.302 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
S78 Traumatic amputation of hip and thigh
0.697 0.303 0.000
S77 Crushing injury of hip and thigh
0.697 0.303 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.697 0.303 0.000
S75 Injury of blood vessels at hip and thigh level
0.697 0.303 0.000
S74 Injury of nerves at hip and thigh level
0.697 0.303 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.697 0.303 0.000
S71 Open wound of hip and thigh
0.697 0.303 0.000
M06.4 Inflammatory polyarthropathy
0.696 0.304 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.696 0.304 0.000
D34 Benign neoplasm of thyroid gland
0.695 0.305 0.000
D35.0 Adrenal gland
0.694 0.306 0.000
A41.9 Septicaemia, unspecified
0.694 0.306 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.694 0.306 0.000
M80 Osteoporosis with pathological fracture
0.694 0.306 0.000
S05 Injury of eye and orbit
0.692 0.307 0.000
Y00-Y09 Assault
0.692 0.308 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.692 0.308 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.692 0.308 0.000
M20-M25 Other joint disorders
0.692 0.308 0.000
E14.8 With unspecified complications
0.691 0.309 0.000
E14.7 With multiple complications
0.691 0.309 0.000
E14.6 With other specified complications
0.691 0.309 0.000
E14.5 With peripheral circulatory complications
0.691 0.309 0.000
E14.4 With neurological complications
0.691 0.309 0.000
E14.2 Withrenal complications
0.691 0.309 0.000
E14.1 With ketoacidosis
0.691 0.309 0.000
E14.0 With coma
0.691 0.309 0.000
S72.1 Pertrochanteric fracture
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.309 0.000
S79 Other and unspecified injuries of hip and thigh
0.690 0.310 0.000
M81.4 Drug-induced osteoporosis
0.690 0.310 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.690 0.310 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.690 0.310 0.000
Z94.8 Other transplanted organ and tissue status
0.689 0.311 0.000
B35 Dermatophytosis
0.689 0.311 0.000
T98 Sequelae of other and unspecified effects of external causes
0.689 0.311 0.000
A41.4 Septicaemia due to anaerobes
0.689 0.311 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.689 0.311 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.689 0.311 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.688 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.688 0.312 0.000
S52.1 Fracture of upper end of radius
0.688 0.312 0.000
T66-T78 Other and unspecified effects of external causes
0.687 0.313 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.687 0.313 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
T90 Sequelae of injuries of head
0.686 0.314 0.000
E22.1 Hyperprolactinaemia
0.685 0.315 0.000
C01 Malignant neoplasm of base of tongue
0.685 0.315 0.000
C77.8 Lymph nodes of multiple regions
0.685 0.315 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.684 0.316 0.000
C51-C58 Malignant neoplasms of female genital organs
0.682 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.682 0.318 0.000
E10.8 With unspecified complications
0.682 0.318 0.000
E10.7 With multiple complications
0.682 0.318 0.000
E10.6 With other specified complications
0.682 0.318 0.000
E10.5 With peripheral circulatory complications
0.682 0.318 0.000
E10.0 With coma
0.682 0.318 0.000
E29 Testicular dysfunction
0.682 0.318 0.000
E23 Hypofunction and other disorders of pituitary gland
0.682 0.318 0.000
E27.5 Adrenomedullary hyperfunction
0.681 0.319 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.681 0.319 0.000
E27.0 Other adrenocortical overactivity
0.681 0.319 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.681 0.319 0.000
Q35-Q37 Cleft lip and cleft palate
0.681 0.319 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.681 0.319 0.000
Z94.4 Liver transplant status
0.680 0.320 0.000
S72.9 Fracture of femur, part unspecified
0.680 0.320 0.000
S72.8 Fractures of other parts of femur
0.680 0.320 0.000
S72.7 Multiple fractures of femur
0.680 0.320 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.678 0.322 0.000
Z94.7 Corneal transplant status
0.677 0.323 0.000
M47.1 Other spondylosis with myelopathy
0.677 0.323 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.677 0.323 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.676 0.324 0.000
T95 Sequelae of burns, corrosions and frostbite
0.676 0.324 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.676 0.324 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.676 0.324 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.676 0.324 0.000
E00 Congenital iodine-deficiency syndrome
0.676 0.324 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.676 0.324 0.000
S06 Intracranial injury
0.676 0.324 0.000
M87 Osteonecrosis
0.676 0.324 0.000
H73 Other disorders of tympanic membrane
0.676 0.324 0.000
E06 Thyroiditis
0.675 0.325 0.000
Z28 Immunisation not carried out
0.674 0.326 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.674 0.326 0.000
Z26 Need for immunisation against other single infectious diseases
0.674 0.326 0.000
Z25 Need for immunisation against other single viral diseases
0.674 0.326 0.000
Z24 Need for immunisation against certain single viral diseases
0.674 0.326 0.000
Z23 Need for immunisation against single bacterial diseases
0.674 0.326 0.000
Z20 Contact with and exposure to communicable diseases
0.674 0.326 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.674 0.326 0.000
M75 Shoulder lesions
0.673 0.327 0.000
W55 Bitten or struck by other mammals
0.672 0.328 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.672 0.328 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.672 0.328 0.000
M47.84 Other spondylosis (Thoracic region)
0.672 0.328 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.672 0.328 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.672 0.328 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.672 0.328 0.000
Z49.1 Extracorporeal dialysis
0.672 0.328 0.000
M06.8 Other specified rheumatoid arthritis
0.671 0.328 0.000
M06.2 Rheumatoid bursitis
0.671 0.328 0.000
M06.1 Adult-onset Still's disease
0.671 0.328 0.000
E40-E46 Malnutrition
0.671 0.328 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.671 0.329 0.000
E13 Other specified diabetes mellitus
0.671 0.329 0.000
M65-M68 Disorders of synovium and tendon
0.670 0.330 0.000
H90.5 Sensorineural hearing loss, unspecified
0.670 0.330 0.000
H69 Other disorders of Eustachian tube
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.669 0.331 0.000
H70 Mastoiditis and related conditions
0.668 0.332 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.668 0.332 0.000
D16 Benign neoplasm of bone and articular cartilage
0.668 0.332 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.667 0.333 0.000
S32.0 Fracture of lumbar vertebra
0.667 0.333 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.333 0.000
S72.01 Fracture of neck of femur (open)
0.666 0.334 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.666 0.334 0.000
D11 Benign neoplasm of major salivary glands
0.666 0.334 0.000
Z72.0 Tobacco use
0.666 0.334 0.000
S50 Superficial injury of forearm
0.665 0.335 0.000
H30-H36 Disorders of choroid and retina
0.665 0.335 0.000
D04 Carcinoma in situ of skin
0.665 0.335 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.665 0.335 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.664 0.336 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.664 0.336 0.000
C79 Secondary malignant neoplasm of other sites
0.664 0.336 0.000
D68 Other coagulation defects
0.664 0.336 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.664 0.336 0.000
S59 Other and unspecified injuries of forearm
0.663 0.336 0.000
S58 Traumatic amputation of forearm
0.663 0.336 0.000
S57 Crushing injury of forearm
0.663 0.336 0.000
S55 Injury of blood vessels at forearm level
0.663 0.336 0.000
S54 Injury of nerves at forearm level
0.663 0.336 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.663 0.336 0.000
S00 Superficial injury of head
0.663 0.337 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.663 0.337 0.000
D10 Benign neoplasm of mouth and pharynx
0.662 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.662 0.338 0.000
Y10-Y34 Event of undetermined intent
0.662 0.338 0.000
X85-X99 Assault
0.662 0.338 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.662 0.338 0.000
X50-X57 Overexertion, travel and privation
0.662 0.338 0.000
X30-X39 Exposure to forces of nature
0.662 0.338 0.000
X20-X29 Contact with venomous animals and plants
0.662 0.338 0.000
X00-X09 Exposure to smoke, fire and flames
0.662 0.338 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.662 0.338 0.000
W75-W84 Other accidental threats to breathing
0.662 0.338 0.000
W65-W74 Accidental drowning and submersion
0.662 0.338 0.000
V98-V99 Other and unspecified transport accidents
0.662 0.338 0.000
V95-V97 Air and space transport accidents
0.662 0.338 0.000
V90-V94 Water transport accidents
0.662 0.338 0.000
V70-V79 Bus occupant injured in transport accident
0.662 0.338 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.662 0.338 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.662 0.338 0.000
V40-V49 Car occupant injured in transport accident
0.662 0.338 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.662 0.338 0.000
V01-V09 Pedestrian injured in transport accident
0.662 0.338 0.000
S52.5 Fracture of lower end of radius
0.662 0.338 0.000
E26.0 Primary hyperaldosteronism
0.660 0.339 0.000
E50-E64 Other nutritional deficiencies
0.660 0.340 0.000
M71 Other bursopathies
0.660 0.340 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.660 0.340 0.000
S51 Open wound of forearm
0.660 0.340 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
K86.1 Other chronic pancreatitis
0.659 0.341 0.000
K82 Other diseases of gallbladder
0.659 0.341 0.000
D30 Benign neoplasm of urinary organs
0.658 0.341 0.000
Z44 Fitting and adjustment of external prosthetic device
0.657 0.343 0.000
Z73 Problems related to life-management difficulty
0.656 0.344 0.000
S98 Traumatic amputation of ankle and foot
0.656 0.344 0.000
S97 Crushing injury of ankle and foot
0.656 0.344 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.656 0.344 0.000
S95 Injury of blood vessels at ankle and foot level
0.656 0.344 0.000
S94 Injury of nerves at ankle and foot level
0.656 0.344 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.656 0.344 0.000
S32.5 Fracture of pubis
0.656 0.344 0.000
S92.5 Fracture of other toe
0.655 0.344 0.000
S12 Fracture of neck
0.655 0.345 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.654 0.345 0.000
T23 Burn and corrosion of wrist and hand
0.654 0.345 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.654 0.346 0.000
Y85 Sequelae of transport accidents
0.654 0.346 0.000
G90-G99 Other disorders of the nervous system
0.653 0.347 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.653 0.347 0.000
S37 Injury of urinary and pelvic organs
0.653 0.347 0.000
S36 Injury of intra-abdominal organs
0.653 0.347 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.653 0.347 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.653 0.347 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.653 0.347 0.000
S31 Open wound of abdomen, lower back and pelvis
0.653 0.347 0.000
V20-V29 Motorcycle rider injured in transport accident
0.653 0.347 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.652 0.347 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.652 0.348 0.000
M45 Ankylosing spondylitis
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.652 0.348 0.000
Y52 Agents primarily affecting the cardiovascular system
0.652 0.348 0.000
D31 Benign neoplasm of eye and adnexa
0.651 0.348 0.000
D29 Benign neoplasm of male genital organs
0.651 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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