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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112143646
log Bayes Factor = 18.4597
Chromosome 2   position 102,617,045  (GRCh37) Explore rs112143646 on Ensembl!
Variant rs112143646 is part of Cluster X0214

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I20 Angina pectoris
0.998 0.002 0.000
I21 Acute myocardial infarction
0.996 0.004 0.000
I20.0 Unstable angina
0.995 0.005 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.993 0.007 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.993 0.007 0.000
K21 Gastro-oesophageal reflux disease
0.992 0.008 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
I21.9 Acute myocardial infarction, unspecified
0.988 0.012 0.000
T81 Complications of procedures, not elsewhere classified
0.987 0.013 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.979 0.021 0.000
O60-O75 Complications of labour and delivery
0.978 0.022 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.974 0.026 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.971 0.029 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.968 0.032 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
K31 Other diseases of stomach and duodenum
0.964 0.036 0.000
S60-S69 Injuries to the wrist and hand
0.959 0.041 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.957 0.043 0.000
R50-R69 General symptoms and signs
0.954 0.046 0.000
I25.1 Atherosclerotic heart disease
0.950 0.050 0.000
K70-K77 Diseases of liver
0.949 0.051 0.000
Chapter X Diseases of the respiratory system
0.945 0.055 0.000
C34 Malignant neoplasm of bronchus and lung
0.940 0.060 0.000
O80-O84 Delivery
0.937 0.063 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.936 0.064 0.000
J90-J94 Other diseases of pleura
0.935 0.065 0.000
R55 Syncope and collapse
0.932 0.068 0.000
R51 Headache
0.931 0.069 0.000
D10-D36 Benign neoplasms
0.929 0.071 0.000
S00-S09 Injuries to the head
0.926 0.074 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.924 0.076 0.000
O72 Postpartum haemorrhage
0.923 0.077 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.922 0.078 0.000
D00-D09 In situ neoplasms
0.918 0.082 0.000
Chapter VI Diseases of the nervous system
0.909 0.091 0.000
I20.9 Angina pectoris, unspecified
0.908 0.092 0.000
J90 Pleural effusion, not elsewhere classified
0.907 0.093 0.000
I24 Other acute ischaemic heart diseases
0.907 0.093 0.000
O47 False labour
0.906 0.094 0.000
M80-M85 Disorders of bone density and structure
0.902 0.098 0.000
W00-W19 Falls
0.901 0.099 0.000
K31.8 Other specified diseases of stomach and duodenum
0.898 0.102 0.000
S00 Superficial injury of head
0.896 0.104 0.000
M54 Dorsalgia
0.892 0.108 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.890 0.110 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.887 0.113 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.885 0.115 0.000
C34.9 Bronchus or lung, unspecified
0.884 0.116 0.000
M50 Cervical disk disorders
0.880 0.120 0.000
M45-M49 Spondylopathies
0.880 0.120 0.000
D17 Benign lipomatous neoplasm
0.879 0.121 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.876 0.124 0.000
O72.1 Other immediate postpartum haemorrhage
0.873 0.127 0.000
I25.2 Old myocardial infarction
0.872 0.128 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.870 0.130 0.000
G20-G26 Extrapyramidal and movement disorders
0.868 0.132 0.000
I24.8 Other forms of acute ischaemic heart disease
0.867 0.133 0.000
I21.4 Acute subendocardial myocardial infarction
0.865 0.135 0.000
C34.1 Upper lobe, bronchus or lung
0.865 0.135 0.000
S80-S89 Injuries to the knee and lower leg
0.861 0.139 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.858 0.142 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.856 0.144 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.855 0.145 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.853 0.147 0.000
M51 Other intervertebral disk disorders
0.852 0.148 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.845 0.155 0.000
O80 Single spontaneous delivery
0.843 0.157 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.841 0.159 0.000
J95-J99 Other diseases of the respiratory system
0.841 0.159 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.841 0.159 0.000
S00.8 Superficial injury of other parts of head
0.840 0.160 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.837 0.163 0.000
R54 Senility
0.837 0.163 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.836 0.164 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.835 0.165 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.833 0.167 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.832 0.168 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.830 0.170 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.828 0.172 0.000
M54.9 Dorsalgia, unspecified
0.826 0.174 0.000
I22 Subsequent myocardial infarction
0.826 0.174 0.000
M70-M79 Other soft tissue disorders
0.825 0.175 0.000
W19 Unspecified fall
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.823 0.177 0.000
S68 Traumatic amputation of wrist and hand
0.823 0.177 0.000
R52 Pain, not elsewhere classified
0.821 0.178 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.821 0.179 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.819 0.181 0.000
K75 Other inflammatory liver diseases
0.818 0.182 0.000
D22 Melanocytic naevi
0.817 0.183 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.817 0.183 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.817 0.183 0.000
S00.0 Superficial injury of scalp
0.816 0.184 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.814 0.186 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.813 0.187 0.000
K73 Chronic hepatitis, not elsewhere classified
0.812 0.188 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.812 0.188 0.000
M47 Spondylosis
0.811 0.189 0.000
J92 Pleural plaque
0.810 0.190 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.810 0.190 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.809 0.191 0.000
S62 Fracture at wrist and hand level
0.809 0.191 0.000
G20 Parkinson's disease
0.808 0.191 0.000
O43 Placental disorders
0.808 0.192 0.000
O82 Single delivery by Caesarean section
0.808 0.192 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.806 0.194 0.000
M05-M14 Inflammatory polyarthropathies
0.805 0.195 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.803 0.197 0.000
S40-S49 Injuries to the shoulder and upper arm
0.803 0.197 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.802 0.198 0.000
K76 Other diseases of liver
0.802 0.198 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.801 0.199 0.000
C51-C58 Malignant neoplasms of female genital organs
0.800 0.200 0.000
O63 Long labour
0.800 0.200 0.000
M54.3 Sciatica
0.799 0.201 0.000
M81 Osteoporosis without pathological fracture
0.799 0.201 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.799 0.201 0.000
C32 Malignant neoplasm of larynx
0.797 0.203 0.000
T87 Complications peculiar to reattachment and amputation
0.796 0.204 0.000
Z04 Examination and observation for other reasons
0.796 0.204 0.000
I30-I52 Other forms of heart disease
0.796 0.204 0.000
D03 Melanoma in situ
0.793 0.207 0.000
K31.4 Gastric diverticulum
0.792 0.208 0.000
O41 Other disorders of amniotic fluid and membranes
0.791 0.209 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.791 0.209 0.000
R53 Malaise and fatigue
0.783 0.217 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.782 0.218 0.000
M50.1 Cervical disk disorder with radiculopathy
0.780 0.220 0.000
K65-K67 Diseases of peritoneum
0.777 0.223 0.000
D34 Benign neoplasm of thyroid gland
0.775 0.225 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.775 0.225 0.000
D06 Carcinoma in situ of cervix uteri
0.775 0.225 0.000
M20-M25 Other joint disorders
0.773 0.227 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.772 0.228 0.000
S65 Injury of blood vessels at wrist and hand level
0.769 0.230 0.000
J93 Pneumothorax
0.767 0.233 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.767 0.233 0.000
S64 Injury of nerves at wrist and hand level
0.766 0.234 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.766 0.234 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.765 0.235 0.000
R63 Symptoms and signs concerning food and fluid intake
0.764 0.236 0.000
D04 Carcinoma in situ of skin
0.760 0.240 0.000
W19.9 Unspecified place
0.757 0.243 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.757 0.243 0.000
O80.0 Spontaneous vertex delivery
0.756 0.244 0.000
Z02 Examination and encounter for administrative purposes
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.755 0.244 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.755 0.245 0.000
Z03.8 Observation for other suspected diseases and conditions
0.755 0.245 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.755 0.245 0.000
D25 Leiomyoma of uterus
0.755 0.245 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.754 0.246 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
M51.2 Other specified intervertebral disk displacement
0.751 0.249 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.750 0.250 0.000
O66 Other obstructed labour
0.750 0.250 0.000
V80-V89 Other land transport accidents
0.748 0.252 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.253 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.746 0.254 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.746 0.254 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.745 0.255 0.000
G25 Other extrapyramidal and movement disorders
0.742 0.258 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.742 0.258 0.000
O47.9 False labour, unspecified
0.741 0.258 0.000
Z34 Supervision of normal pregnancy
0.741 0.259 0.000
Z63 Other problems related to primary support group, including family circumstances
0.740 0.260 0.000
Z22 Carrier of infectious disease
0.740 0.260 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.739 0.261 0.000
D11 Benign neoplasm of major salivary glands
0.739 0.261 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.738 0.262 0.000
M40-M43 Deforming dorsopathies
0.737 0.263 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.737 0.263 0.000
M10 Gout
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
Z94 Transplanted organ and tissue status
0.735 0.265 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.734 0.266 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.733 0.267 0.000
M86-M90 Other osteopathies
0.733 0.267 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.733 0.267 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.731 0.269 0.000
K26 Duodenal ulcer
0.730 0.270 0.000
S67 Crushing injury of wrist and hand
0.728 0.272 0.000
J86 Pyothorax
0.728 0.272 0.000
S06 Intracranial injury
0.727 0.273 0.000
I35 Nonrheumatic aortic valve disorders
0.727 0.273 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.727 0.273 0.000
M47.8 Other spondylosis
0.727 0.273 0.000
I25.5 Ischaemic cardiomyopathy
0.726 0.274 0.000
M81.9 Osteoporosis, unspecified
0.725 0.275 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.725 0.275 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.724 0.275 0.000
G30-G32 Other degenerative diseases of the nervous system
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.278 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.721 0.279 0.000
J98 Other respiratory disorders
0.720 0.280 0.000
Z37 Outcome of delivery
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
J60-J70 Lung diseases due to external agents
0.716 0.284 0.000
O82.0 Delivery by elective Caesarean section
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
M23 Internal derangement of knee
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
Z98 Other postsurgical states
0.715 0.285 0.000
T85.2 Mechanical complication of intraocular lens
0.715 0.285 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.714 0.286 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.714 0.286 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.714 0.286 0.000
O00-O08 Pregnancy with abortive outcome
0.714 0.286 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
K74 Fibrosis and cirrhosis of liver
0.712 0.288 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
K28 Gastrojejunal ulcer
0.712 0.288 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.712 0.288 0.000
Z95.2 Presence of prosthetic heart valve
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.711 0.289 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.710 0.289 0.000
I31 Other diseases of pericardium
0.709 0.291 0.000
D22.5 Melanocytic naevi of trunk
0.709 0.291 0.000
Z29 Need for other prophylactic measures
0.708 0.292 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.708 0.292 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.708 0.292 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.708 0.292 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.708 0.292 0.000
T81.9 Unspecified complication of procedure
0.707 0.292 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.707 0.292 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.707 0.292 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.707 0.292 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.707 0.293 0.000
C64-C68 Malignant neoplasms of urinary tract
0.707 0.293 0.000
O48 Prolonged pregnancy
0.706 0.294 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.705 0.295 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.705 0.295 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.705 0.295 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.705 0.295 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.704 0.296 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.704 0.296 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.704 0.296 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.704 0.296 0.000
W13 Fall from, out of or through building or structure
0.704 0.296 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.704 0.296 0.000
M84 Disorders of continuity of bone
0.703 0.297 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.703 0.297 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.703 0.297 0.000
M50.3 Other cervical disk degeneration
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.702 0.298 0.000
O74 Complications of anaesthesia during labour and delivery
0.701 0.299 0.000
O71 Other obstetric trauma
0.701 0.299 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.701 0.299 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.701 0.299 0.000
O61 Failed induction of labour
0.701 0.299 0.000
O60 Preterm delivery
0.701 0.299 0.000
S50-S59 Injuries to the elbow and forearm
0.701 0.299 0.000
O73 Retained placenta and membranes, without haemorrhage
0.701 0.299 0.000
K22 Other diseases of oesophagus
0.699 0.301 0.000
O45 Premature separation of placenta [abruptio placentae]
0.698 0.302 0.000
O44 Placenta praevia
0.698 0.302 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.698 0.302 0.000
O33 Maternal care for known or suspected disproportion
0.698 0.302 0.000
O31 Complications specific to multiple gestation
0.698 0.302 0.000
O40 Polyhydramnios
0.698 0.302 0.000
R52.2 Other chronic pain
0.698 0.302 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.698 0.302 0.000
K75.9 Inflammatory liver disease, unspecified
0.698 0.302 0.000
Z32 Pregnancy examination and test
0.697 0.303 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.697 0.303 0.000
S69 Other and unspecified injuries of wrist and hand
0.697 0.303 0.000
K72 Hepatic failure, not elsewhere classified
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.694 0.305 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.694 0.306 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.694 0.306 0.000
C31 Malignant neoplasm of accessory sinuses
0.694 0.306 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.694 0.306 0.000
C37 Malignant neoplasm of thymus
0.694 0.306 0.000
C33 Malignant neoplasm of trachea
0.694 0.306 0.000
J92.0 Pleural plaque with presence of asbestos
0.694 0.306 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.693 0.307 0.000
K25 Gastric ulcer
0.693 0.307 0.000
Z95.1 Presence of aortocoronary bypass graft
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V40-V49 Car occupant injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
K31.6 Fistula of stomach and duodenum
0.691 0.309 0.000
K31.5 Obstruction of duodenum
0.691 0.309 0.000
K31.3 Pylorospasm, not elsewhere classified
0.691 0.309 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.691 0.309 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.691 0.309 0.000
K31.0 Acute dilatation of stomach
0.691 0.309 0.000
S02 Fracture of skull and facial bones
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.309 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.690 0.310 0.000
S20-S29 Injuries to the thorax
0.690 0.310 0.000
M54.1 Radiculopathy
0.688 0.312 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.688 0.312 0.000
Z04.8 Examination and observation for other specified reasons
0.688 0.312 0.000
Z95.4 Presence of other heart-valve replacement
0.688 0.312 0.000
R61 Hyperhidrosis
0.688 0.312 0.000
O47.0 False labour before 37 completed weeks of gestation
0.688 0.312 0.000
D32 Benign neoplasm of meninges
0.688 0.312 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.688 0.312 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.687 0.312 0.000
M10.9 Gout, unspecified
0.687 0.313 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.686 0.314 0.000
O62 Abnormalities of forces of labour
0.686 0.314 0.000
S62.3 Fracture of other metacarpal bone
0.685 0.315 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.684 0.316 0.000
R62 Lack of expected normal physiological development
0.684 0.316 0.000
R57 Shock, not elsewhere classified
0.684 0.316 0.000
R64 Cachexia
0.684 0.316 0.000
R58 Haemorrhage, not elsewhere classified
0.684 0.316 0.000
K76.9 Liver disease, unspecified
0.684 0.316 0.000
S00.3 Superficial injury of nose
0.684 0.316 0.000
M54.39 Sciatica (Site unspecified)
0.684 0.316 0.000
O42 Premature rupture of membranes
0.683 0.317 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.682 0.318 0.000
S60 Superficial injury of wrist and hand
0.681 0.319 0.000
K29 Gastritis and duodenitis
0.681 0.319 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.681 0.319 0.000
J94 Other pleural conditions
0.681 0.319 0.000
R47-R49 Symptoms and signs involving speech and voice
0.681 0.319 0.000
K77 Liver disorders in diseases classified elsewhere
0.680 0.319 0.000
K71 Toxic liver disease
0.680 0.319 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.680 0.320 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.678 0.321 0.000
R52.1 Chronic intractable pain
0.678 0.321 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.678 0.322 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.678 0.322 0.000
K76.8 Other specified diseases of liver
0.677 0.322 0.000
S86 Injury of muscle and tendon at lower leg level
0.677 0.323 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.676 0.324 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.676 0.324 0.000
R63.0 Anorexia
0.676 0.324 0.000
M54.4 Lumbago with sciatica
0.675 0.325 0.000
C32.9 Larynx, unspecified
0.675 0.325 0.000
M23.3 Other meniscus derangements
0.675 0.325 0.000
I20.1 Angina pectoris with documented spasm
0.674 0.325 0.000
C34.8 Overlapping lesion of bronchus and lung
0.674 0.326 0.000
C34.2 Middle lobe, bronchus or lung
0.674 0.326 0.000
C34.0 Main bronchus
0.674 0.326 0.000
M80 Osteoporosis with pathological fracture
0.674 0.326 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.674 0.326 0.000
Z35 Supervision of high-risk pregnancy
0.674 0.326 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.673 0.326 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.673 0.327 0.000
D06.9 Cervix, unspecified
0.672 0.328 0.000
K70 Alcoholic liver disease
0.672 0.328 0.000
T66-T78 Other and unspecified effects of external causes
0.672 0.328 0.000
K31.7 Polyp of stomach and duodenum
0.672 0.328 0.000
O84 Multiple delivery
0.671 0.328 0.000
O83 Other assisted single delivery
0.671 0.328 0.000
O81 Single delivery by forceps and vacuum extractor
0.671 0.328 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.671 0.329 0.000
O97 Death from sequelae of direct obstetric causes
0.671 0.329 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.671 0.329 0.000
O95 Obstetric death of unspecified cause
0.671 0.329 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.671 0.329 0.000
G90-G99 Other disorders of the nervous system
0.671 0.329 0.000
D09 Carcinoma in situ of other and unspecified sites
0.671 0.329 0.000
O72.0 Third-stage haemorrhage
0.671 0.329 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.670 0.330 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.670 0.330 0.000
M54.36 Sciatica (Lumbar region)
0.670 0.330 0.000
J91 Pleural effusion in conditions classified elsewhere
0.670 0.330 0.000
K66 Other disorders of peritoneum
0.668 0.332 0.000
D27 Benign neoplasm of ovary
0.668 0.332 0.000
D31 Benign neoplasm of eye and adnexa
0.666 0.334 0.000
D30 Benign neoplasm of urinary organs
0.666 0.334 0.000
D29 Benign neoplasm of male genital organs
0.666 0.334 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.666 0.334 0.000
D26 Other benign neoplasms of uterus
0.666 0.334 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.666 0.334 0.000
D19 Benign neoplasm of mesothelial tissue
0.666 0.334 0.000
D16 Benign neoplasm of bone and articular cartilage
0.666 0.334 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.666 0.334 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.666 0.334 0.000
D10 Benign neoplasm of mouth and pharynx
0.666 0.334 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.666 0.334 0.000
O36 Maternal care for other known or suspected foetal problems
0.666 0.334 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.665 0.335 0.000
Q00-Q07 Congenital malformations of the nervous system
0.664 0.336 0.000
S08 Traumatic amputation of part of head
0.664 0.336 0.000
S07 Crushing injury of head
0.664 0.336 0.000
S05 Injury of eye and orbit
0.664 0.336 0.000
S04 Injury of cranial nerves
0.664 0.336 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
M47.1 Other spondylosis with myelopathy
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.663 0.336 0.000
M47.2 Other spondylosis with radiculopathy
0.663 0.336 0.000
Z83 Family history of other specific disorders
0.663 0.337 0.000
J86.9 Pyothorax without fistula
0.663 0.337 0.000
O43.1 Malformation of placenta
0.662 0.338 0.000
K27 Peptic ulcer, site unspecified
0.662 0.338 0.000
O72.3 Postpartum coagulation defects
0.662 0.338 0.000
Z10 Routine general health check-up of defined subpopulation
0.661 0.339 0.000
Z03.3 Observation for suspected nervous system disorder
0.661 0.339 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.660 0.340 0.000
O16 Unspecified maternal hypertension
0.660 0.340 0.000
O80.9 Single spontaneous delivery, unspecified
0.660 0.340 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.658 0.342 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.658 0.342 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.658 0.342 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.658 0.342 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.658 0.342 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.658 0.342 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.658 0.342 0.000
M85 Other disorders of bone density and structure
0.658 0.342 0.000
Z95.0 Presence of cardiac pacemaker
0.658 0.342 0.000
I51 Complications and ill-defined descriptions of heart disease
0.657 0.343 0.000
M50.0 Cervical disk disorder with myelopathy
0.657 0.343 0.000
Z11.2 Special screening examination for other bacterial diseases
0.657 0.343 0.000
R68 Other general symptoms and signs
0.657 0.343 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.656 0.344 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.655 0.344 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.655 0.344 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.652 0.347 0.000
K73.9 Chronic hepatitis, unspecified
0.652 0.348 0.000
G70-G73 Diseases of myoneural junction and muscle
0.652 0.348 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.652 0.348 0.000
O30 Multiple gestation
0.652 0.348 0.000
Y84.2 Radiological procedure and radiotherapy
0.652 0.348 0.000
T87.4 Infection of amputation stump
0.651 0.349 0.000
I24.1 Dressler's syndrome
0.650 0.350 0.000
Z89 Acquired absence of limb
0.650 0.350 0.000
D60-D64 Aplastic and other anaemias
0.650 0.350 0.000
R73 Elevated blood glucose level
0.649 0.351 0.000
R29.6 Tendency to fall, not elsewhere classified
0.648 0.352 0.000
D03.5 Melanoma in situ of trunk
0.647 0.352 0.000
J93.9 Pneumothorax, unspecified
0.647 0.353 0.000
M83 Adult osteomalacia
0.647 0.353 0.000
M82 Osteoporosis in diseases classified elsewhere
0.647 0.353 0.000
Z37.0 Single live birth
0.647 0.353 0.000
S82 Fracture of lower leg, including ankle
0.647 0.353 0.000
W18 Other fall on same level
0.646 0.354 0.000
W17 Other fall from one level to another
0.646 0.354 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.646 0.354 0.000
W15 Fall from cliff
0.646 0.354 0.000
W14 Fall from tree
0.646 0.354 0.000
W12 Fall on and from scaffolding
0.646 0.354 0.000
W11 Fall on and from ladder
0.646 0.354 0.000
W10 Fall on and from stairs and steps
0.646 0.354 0.000
W09 Fall involving playground equipment
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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