TreeWAS – Variant ID: rs117155878

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
M20-M25 Other joint disorders	0.996	0.004
Chapter VI Diseases of the nervous system	0.995	0.005
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.993	0.007
M23 Internal derangement of knee	0.992	0.008
E70-E90 Metabolic disorders	0.990	0.010
M23.2 Derangement of meniscus due to old tear or injury	0.988	0.012
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.985	0.015
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.984	0.016
Chapter II Neoplasms	0.984	0.016
R04 Haemorrhage from respiratory passages	0.979	0.021
Chapter IX Diseases of the circulatory system	0.976	0.024
R91 Abnormal findings on diagnostic imaging of lung	0.976	0.024
M70-M79 Other soft tissue disorders	0.975	0.025
G50-G59 Nerve, nerve root and plexus disorders	0.975	0.025
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.974	0.026
J34 Other disorders of nose and nasal sinuses	0.972	0.028
J90-J94 Other diseases of pleura	0.971	0.029
J33 Nasal polyp	0.970	0.030
I30-I52 Other forms of heart disease	0.952	0.048
R04.2 Haemoptysis	0.952	0.048
J33.9 Nasal polyp, unspecified	0.951	0.049
J90 Pleural effusion, not elsewhere classified	0.949	0.051
I35 Nonrheumatic aortic valve disorders	0.948	0.052
R06 Abnormalities of breathing	0.946	0.054
G90-G99 Other disorders of the nervous system	0.944	0.056
Chapter I Certain infectious and parasitic diseases	0.943	0.057
D37-D48 Neoplasms of uncertain or unknown behaviour	0.942	0.058
R04.0 Epistaxis	0.938	0.062
S00-S09 Injuries to the head	0.935	0.065
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.933	0.067
I35.0 Aortic (valve) stenosis	0.928	0.072
M15-M19 Arthrosis	0.927	0.073
M75 Shoulder lesions	0.925	0.075
R06.0 Dyspnoea	0.920	0.080
G93 Other disorders of brain	0.908	0.092
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.907	0.093
E87 Other disorders of fluid, electrolyte and acid-base balance	0.905	0.095
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.903	0.097
G56 Mononeuropathies of upper limb	0.901	0.099
C50-C50 Malignant neoplasm of breast	0.899	0.101
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.899	0.101
M40-M43 Deforming dorsopathies	0.899	0.101
Chapter VIII Diseases of the ear and mastoid process	0.899	0.101
A30-A49 Other bacterial diseases	0.899	0.101
J34.8 Other specified disorders of nose and nasal sinuses	0.898	0.102
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.897	0.103
J60-J70 Lung diseases due to external agents	0.897	0.103
M18 Arthrosis of first carpometacarpal joint	0.893	0.107
J30 Vasomotor and allergic rhinitis	0.892	0.108
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.885	0.115
J32 Chronic sinusitis	0.884	0.116
M45-M49 Spondylopathies	0.883	0.117
E83 Disorders of mineral metabolism	0.872	0.128
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.869	0.131
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.865	0.135
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.863	0.137
I46 Cardiac arrest	0.862	0.138
E87.6 Hypokalaemia	0.858	0.142
A41 Other septicaemia	0.856	0.144
G93.6 Cerebral oedema	0.853	0.147
J80-J84 Other respiratory diseases principally affecting the interstitium	0.851	0.149
M77 Other enthesopathies	0.850	0.150
Chapter XIV Diseases of the genitourinary system	0.849	0.151
I70-I79 Diseases of arteries, arterioles and capillaries	0.848	0.152
E86 Volume depletion	0.846	0.154
I35.1 Aortic (valve) insufficiency	0.846	0.154
E00-E07 Disorders of thyroid gland	0.845	0.155
I31 Other diseases of pericardium	0.844	0.156
R94 Abnormal results of function studies	0.844	0.156
M65-M68 Disorders of synovium and tendon	0.842	0.158
J36 Peritonsillar abscess	0.841	0.159
J34.2 Deviated nasal septum	0.839	0.161
C50 Malignant neoplasm of breast	0.839	0.161
I60-I69 Cerebrovascular diseases	0.839	0.161
S80-S89 Injuries to the knee and lower leg	0.834	0.166
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.832	0.168
Chapter XXI Factors influencing health status and contact with health services	0.832	0.168
M35 Other systemic involvement of connective tissue	0.832	0.168
J92 Pleural plaque	0.827	0.173
E65-E68 Obesity and other hyperalimentation	0.824	0.176
E10-E14 Diabetes mellitus	0.822	0.178
I35.2 Aortic (valve) stenosis with insufficiency	0.821	0.179
H60-H62 Diseases of external ear	0.820	0.180
S05 Injury of eye and orbit	0.819	0.181
S06 Intracranial injury	0.819	0.181
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.818	0.181
J69 Pneumonitis due to solids and liquids	0.814	0.186
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.812	0.188
G00-G09 Inflammatory diseases of the central nervous system	0.812	0.188
N10-N16 Renal tubulo-interstitial diseases	0.810	0.190
M75.0 Adhesive capsulitis of shoulder	0.810	0.190
I10-I15 Hypertensive diseases	0.810	0.190
Z00-Z13 Persons encountering health services for examination and investigation	0.809	0.191
I69 Sequelae of cerebrovascular disease	0.808	0.192
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.807	0.193
I46.0 Cardiac arrest with successful resuscitation	0.807	0.193
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.805	0.195
S70-S79 Injuries to the hip and thigh	0.804	0.196
E89.0 Postprocedural hypothyroidism	0.799	0.201
M60-M63 Disorders of muscles	0.798	0.202
G56.0 Carpal tunnel syndrome	0.797	0.203
I31.3 Pericardial effusion (noninflammatory)	0.796	0.204
C79 Secondary malignant neoplasm of other sites	0.796	0.204
J39 Other diseases of upper respiratory tract	0.796	0.204
E87.2 Acidosis	0.795	0.205
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.795	0.205
E83.1 Disorders of iron metabolism	0.793	0.207
M23.4 Loose body in knee	0.793	0.207
S40-S49 Injuries to the shoulder and upper arm	0.793	0.207
J35 Chronic diseases of tonsils and adenoids	0.792	0.208
N17-N19 Renal failure	0.792	0.208
M24 Other specific joint derangements	0.791	0.209
R03 Abnormal blood-pressure reading, without diagnosis	0.791	0.209
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.789	0.211
A41.5 Septicaemia due to other Gram-negative organisms	0.788	0.212
M21 Other acquired deformities of limbs	0.787	0.213
R06.8 Other and unspecified abnormalities of breathing	0.786	0.214
J30.4 Allergic rhinitis, unspecified	0.785	0.215
B65-B83 Helminthiases	0.783	0.217
J34.3 Hypertrophy of nasal turbinates	0.782	0.218
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.782	0.218
M71 Other bursopathies	0.781	0.219
T36-T50 Poisoning by drugs, medicaments and biological substances	0.780	0.220
M45 Ankylosing spondylitis	0.780	0.220
Z03 Medical observation and evaluation for suspected diseases and conditions	0.779	0.221
M05-M14 Inflammatory polyarthropathies	0.779	0.221
R94.5 Abnormal results of liver function studies	0.779	0.221
G30-G32 Other degenerative diseases of the nervous system	0.778	0.222
Z13 Special screening examination for other diseases and disorders	0.778	0.222
S00 Superficial injury of head	0.778	0.222
M41 Scoliosis	0.775	0.225
G54 Nerve root and plexus disorders	0.774	0.226
G56.2 Lesion of ulnar nerve	0.773	0.227
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.769	0.231
I12 Hypertensive renal disease	0.769	0.231
Chapter XX External causes of morbidity and mortality	0.769	0.231
C50.4 Upper-outer quadrant of breast	0.766	0.234
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.765	0.235
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.765	0.235
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.765	0.235
C64-C68 Malignant neoplasms of urinary tract	0.763	0.237
T93 Sequelae of injuries of lower limb	0.763	0.237
B95-B98 Bacterial, viral and other infectious agents	0.762	0.238
M19 Other arthrosis	0.760	0.240
M75.4 Impingement syndrome of shoulder	0.759	0.241
S90-S99 Injuries to the ankle and foot	0.759	0.241
M31 Other necrotising vasculopathies	0.758	0.242
G55.2 Nerve root and plexus compressions in spondylosis	0.757	0.243
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.757	0.243
M75.2 Bicipital tendinitis	0.756	0.244
C51-C58 Malignant neoplasms of female genital organs	0.756	0.244
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.755	0.245
J69.0 Pneumonitis due to food and vomit	0.755	0.245
R50-R69 General symptoms and signs	0.755	0.245
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.755	0.245
T66-T78 Other and unspecified effects of external causes	0.753	0.247
I71 Aortic aneurysm and dissection	0.752	0.248
S01 Open wound of head	0.750	0.250
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.750	0.250
M43 Other deforming dorsopathies	0.750	0.250
G93.3 Postviral fatigue syndrome	0.750	0.250
E40-E46 Malnutrition	0.749	0.251
M46 Other inflammatory spondylopathies	0.748	0.252
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.748	0.252
M34 Systemic sclerosis	0.747	0.253
S10-S19 Injuries to the neck	0.747	0.253
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.747	0.253
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.746	0.253
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.745	0.255
J34.1 Cyst and mucocele of nose and nasal sinus	0.743	0.257
M70 Soft tissue disorders related to use, overuse and pressure	0.743	0.257
Z03.4 Observation for suspected myocardial infarction	0.743	0.257
M86-M90 Other osteopathies	0.742	0.258
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.740	0.260
D45 Polycythaemia vera	0.740	0.260
E14 Unspecified diabetes mellitus	0.739	0.261
R72 Abnormality of white blood cells, not elsewhere classified	0.739	0.261
H61 Other disorders of external ear	0.738	0.262
M75.5 Bursitis of shoulder	0.737	0.263
G80-G83 Cerebral palsy and other paralytic syndromes	0.737	0.263
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.736	0.264
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.735	0.265
G51 Facial nerve disorders	0.733	0.267
C50.5 Lower-outer quadrant of breast	0.733	0.267
N18 Chronic renal failure	0.733	0.267
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.732	0.268
Z03.9 Observation for suspected disease or condition, unspecified	0.732	0.268
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.731	0.269
J33.0 Polyp of nasal cavity	0.730	0.270
M65 Synovitis and tenosynovitis	0.730	0.270
E88 Other metabolic disorders	0.729	0.270
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.729	0.270
M00-M03 Infectious arthropathies	0.729	0.270
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.729	0.271
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.728	0.272
G93.2 Benign intracranial hypertension	0.728	0.272
E89.3 Postprocedural hypopituitarism	0.726	0.274
I95-I99 Other and unspecified disorders of the circulatory system	0.726	0.274
Q60-Q64 Congenital malformations of the urinary system	0.725	0.275
J80 Adult respiratory distress syndrome	0.725	0.275
I33 Acute and subacute endocarditis	0.724	0.276
N20-N23 Urolithiasis	0.722	0.278
R06.2 Wheezing	0.721	0.279
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.720	0.280
G96 Other disorders of central nervous system	0.720	0.280
M23.3 Other meniscus derangements	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J37 Chronic laryngitis and laryngotracheitis	0.717	0.283
M72 Fibroblastic disorders	0.716	0.283
A41.9 Septicaemia, unspecified	0.716	0.284
A80-A89 Viral infections of the central nervous system	0.716	0.284
I35.9 Aortic valve disorder, unspecified	0.716	0.284
S80 Superficial injury of lower leg	0.716	0.284
I69.3 Sequelae of cerebral infarction	0.715	0.285
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.715	0.285
Q20-Q28 Congenital malformations of the circulatory system	0.715	0.285
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.714	0.286
M33 Dermatopolymyositis	0.714	0.286
M32 Systemic lupus erythematosus	0.714	0.286
M30 Polyarteritis nodosa and related conditions	0.714	0.286
M91-M94 Chondropathies	0.713	0.287
G70-G73 Diseases of myoneural junction and muscle	0.713	0.287
R95-R99 Ill-defined and unknown causes of mortality	0.713	0.287
M75.1 Rotator cuff syndrome	0.712	0.288
J32.4 Chronic pansinusitis	0.712	0.288
T33-T35 Frostbite	0.712	0.288
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288
T00-T07 Injuries involving multiple body regions	0.712	0.288
M77.0 Medial epicondylitis	0.711	0.289
H80-H83 Diseases of inner ear	0.711	0.289
M23.9 Internal derangement of knee, unspecified	0.711	0.289
M23.6 Other spontaneous disruption of ligament(s) of knee	0.711	0.289
M23.1 Discoid meniscus (congenital)	0.711	0.289
M23.0 Cystic meniscus	0.711	0.289
J32.0 Chronic maxillary sinusitis	0.711	0.289
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.710	0.290
Z09.0 Follow-up examination after surgery for other conditions	0.710	0.290
E85 Amyloidosis	0.710	0.290
E84 Cystic fibrosis	0.710	0.290
E79 Disorders of purine and pyrimidine metabolism	0.710	0.290
E77 Disorders of glycoprotein metabolism	0.710	0.290
E76 Disorders of glycosaminoglycan metabolism	0.710	0.290
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.710	0.290
E74 Other disorders of carbohydrate metabolism	0.710	0.290
E73 Lactose intolerance	0.710	0.290
E72 Other disorders of amino-acid metabolism	0.710	0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.710	0.290
E70 Disorders of aromatic amino-acid metabolism	0.710	0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.710	0.290
S60-S69 Injuries to the wrist and hand	0.709	0.291
J30.1 Allergic rhinitis due to pollen	0.709	0.291
T79-T79 Certain early complications of trauma	0.709	0.291
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.708	0.291
S50-S59 Injuries to the elbow and forearm	0.708	0.292
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.707	0.293
E04 Other non-toxic goitre	0.707	0.293
M23.5 Chronic instability of knee	0.707	0.293
N18.9 Chronic renal failure, unspecified	0.706	0.294
M45.X9 Ankylosing spondylitis (Site unspecified)	0.706	0.294
I12.0 Hypertensive renal disease with renal failure	0.706	0.294
R92 Abnormal findings on diagnostic imaging of breast	0.706	0.294
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.705	0.295
C40-C41 Malignant neoplasms of bone and articular cartilage	0.705	0.295
R47-R49 Symptoms and signs involving speech and voice	0.705	0.295
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.705	0.295
T15-T19 Effects of foreign body entering through natural orifice	0.704	0.296
M35.3 Polymyalgia rheumatica	0.703	0.297
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.703	0.297
M23.8 Other internal derangements of knee	0.702	0.297
R03.1 Nonspecific low blood-pressure reading	0.702	0.298
B15-B19 Viral hepatitis	0.702	0.298
R04.9 Haemorrhage from respiratory passages, unspecified	0.702	0.298
R04.8 Haemorrhage from other sites in respiratory passages	0.702	0.298
R04.1 Haemorrhage from throat	0.702	0.298
D37.4 Colon	0.701	0.299
I00-I02 Acute rheumatic fever	0.700	0.300
E66 Obesity	0.700	0.300
C50.9 Breast, unspecified	0.699	0.301
M76 Enthesopathies of lower limb, excluding foot	0.699	0.301
M73 Soft tissue disorders in diseases classified elsewhere	0.699	0.301
G59 Mononeuropathy in diseases classified elsewhere	0.699	0.301
G58 Other mononeuropathies	0.699	0.301
G53 Cranial nerve disorders in diseases classified elsewhere	0.699	0.301
G52 Disorders of other cranial nerves	0.699	0.301
Chapter XXII Codes for special purposes	0.698	0.302
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.698	0.302
J34.0 Abscess, furuncle and carbuncle of nose	0.697	0.303
J94 Other pleural conditions	0.696	0.304
R54 Senility	0.696	0.304
E14.9 Without complications	0.696	0.304
I73 Other peripheral vascular diseases	0.696	0.304
J33.1 Polypoid sinus degeneration	0.696	0.304
Q50-Q56 Congenital malformations of genital organs	0.695	0.305
J95-J99 Other diseases of the respiratory system	0.695	0.305
J92.0 Pleural plaque with presence of asbestos	0.694	0.306
I61 Intracerebral haemorrhage	0.694	0.306
J32.9 Chronic sinusitis, unspecified	0.693	0.307
A46 Erysipelas	0.693	0.307
S00.0 Superficial injury of scalp	0.692	0.308
J35.0 Chronic tonsillitis	0.692	0.308
S05.1 Contusion of eyeball and orbital tissues	0.691	0.308
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.691	0.309
M80-M85 Disorders of bone density and structure	0.689	0.310
Q38-Q45 Other congenital malformations of the digestive system	0.689	0.311
N10 Acute tubulo-interstitial nephritis	0.689	0.311
R90 Abnormal findings on diagnostic imaging of central nervous system	0.688	0.312
C64 Malignant neoplasm of kidney, except renal pelvis	0.687	0.313
D00-D09 In situ neoplasms	0.687	0.313
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.687	0.313
M41.9 Scoliosis, unspecified	0.686	0.314
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.686	0.314
I52 Other heart disorders in diseases classified elsewhere	0.683	0.317
I48 Atrial fibrillation and flutter	0.683	0.317
I43 Cardiomyopathy in diseases classified elsewhere	0.683	0.317
I41 Myocarditis in diseases classified elsewhere	0.683	0.317
I40 Acute myocarditis	0.683	0.317
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.683	0.317
I37 Pulmonary valve disorders	0.683	0.317
I36 Nonrheumatic tricuspid valve disorders	0.683	0.317
I32 Pericarditis in diseases classified elsewhere	0.683	0.317
I30 Acute pericarditis	0.683	0.317
G12 Spinal muscular atrophy and related syndromes	0.681	0.319
I35.8 Other aortic valve disorders	0.680	0.320
M17 Gonarthrosis [arthrosis of knee]	0.679	0.321
D37.0 Lip, oral cavity and pharynx	0.679	0.321
R06.7 Sneezing	0.678	0.322
R06.6 Hiccough	0.678	0.322
R06.3 Periodic breathing	0.678	0.322
R06.1 Stridor	0.678	0.322
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.677	0.322
M77.4 Metatarsalgia	0.677	0.323
R02 Gangrene, not elsewhere classified	0.677	0.323
I47 Paroxysmal tachycardia	0.677	0.323
G94 Other disorders of brain in diseases classified elsewhere	0.676	0.323
G90 Disorders of autonomic nervous system	0.676	0.323
G98 Other disorders of nervous system, not elsewhere classified	0.676	0.323
G92 Toxic encephalopathy	0.676	0.323
B99-B99 Other infectious diseases	0.676	0.324
B90-B94 Sequelae of infectious and parasitic diseases	0.676	0.324
B85-B89 Pediculosis, acariasis and other infestations	0.676	0.324
B50-B64 Protozoal diseases	0.676	0.324
B20-B24 Human immunodeficiency virus [HIV] disease	0.676	0.324
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.676	0.324
A75-A79 Rickettsioses	0.676	0.324
A70-A74 Other diseases caused by chlamydiae	0.676	0.324
A65-A69 Other spirochaetal diseases	0.676	0.324
A20-A28 Certain zoonotic bacterial diseases	0.676	0.324
A15-A19 Tuberculosis	0.676	0.324
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.676	0.324
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.676	0.324
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.676	0.324
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.676	0.324
M19.9 Arthrosis, unspecified	0.676	0.324
I72 Other aneurysm	0.675	0.325
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.673	0.327
A41.8 Other specified septicaemia	0.673	0.327
R76 Other abnormal immunological findings in serum	0.673	0.327
C43-C44 Melanoma and other malignant neoplasms of skin	0.672	0.328
N20 Calculus of kidney and ureter	0.671	0.329
I49 Other cardiac arrhythmias	0.671	0.329
E87.7 Fluid overload	0.671	0.329
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.671	0.329
S08 Traumatic amputation of part of head	0.671	0.329
S07 Crushing injury of head	0.671	0.329
S04 Injury of cranial nerves	0.671	0.329
S03 Dislocation, sprain and strain of joints and ligaments of head	0.671	0.329
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.670	0.330
E13 Other specified diabetes mellitus	0.669	0.331
T92 Sequelae of injuries of upper limb	0.669	0.331
A50-A64 Infections with a predominantly sexual mode of transmission	0.669	0.331
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.669	0.331
G55.0 Nerve root and plexus compressions in neoplastic disease	0.669	0.331
E20-E35 Disorders of other endocrine glands	0.668	0.332
B80 Enterobiasis	0.668	0.332
C80 Malignant neoplasm without specification of site	0.667	0.333
S05.8 Other injuries of eye and orbit	0.667	0.333
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.667	0.333
I12.9 Hypertensive renal disease without renal failure	0.667	0.333
E87.0 Hyperosmolality and hypernatraemia	0.667	0.333
A49 Bacterial infection of unspecified site	0.666	0.334
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.666	0.334
S06.6 Traumatic subarachnoid haemorrhage	0.665	0.335
M15 Polyarthrosis	0.665	0.335
G95 Other diseases of spinal cord	0.665	0.335
E05 Thyrotoxicosis [hyperthyroidism]	0.664	0.336
M75.8 Other shoulder lesions	0.663	0.337
M75.9 Shoulder lesion, unspecified	0.663	0.337
I38 Endocarditis, valve unspecified	0.662	0.338
S06.5 Traumatic subdural haemorrhage	0.661	0.339
R51 Headache	0.661	0.339
H61.0 Perichondritis of external ear	0.660	0.340
C71 Malignant neoplasm of brain	0.659	0.341
H60 Otitis externa	0.657	0.343
J32.8 Other chronic sinusitis	0.657	0.343
S01.8 Open wound of other parts of head	0.657	0.343
E78.2 Mixed hyperlipidaemia	0.656	0.344
G06 Intracranial and intraspinal abscess and granuloma	0.656	0.344
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.653	0.347
M62 Other disorders of muscle	0.653	0.347
M46.9 Inflammatory spondylopathy, unspecified	0.652	0.348
B25-B34 Other viral diseases	0.652	0.348
G93.9 Disorder of brain, unspecified	0.651	0.349
G93.7 Reye's syndrome	0.651	0.349
G93.5 Compression of brain	0.651	0.349
G93.4 Encephalopathy, unspecified	0.651	0.349
G93.1 Anoxic brain damage, not elsewhere classified	0.651	0.349
G93.0 Cerebral cysts	0.651	0.349
I71.3 Abdominal aortic aneurysm, ruptured	0.651	0.349
J91 Pleural effusion in conditions classified elsewhere	0.651	0.349
M23.49 Loose body in knee-Unspec lig/men	0.650	0.350
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.649	0.351
E87.4 Mixed disorder of acid-base balance	0.649	0.351
E87.3 Alkalosis	0.649	0.351
M22 Disorders of patella	0.649	0.351
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.649	0.351
E06 Thyroiditis	0.649	0.351
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.648	0.352
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.648	0.352
J39.2 Other diseases of pharynx	0.648	0.352
N13 Obstructive and reflux uropathy	0.648	0.352
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.647	0.352
Q80-Q89 Other congenital malformations	0.647	0.352
Q35-Q37 Cleft lip and cleft palate	0.647	0.352
Q30-Q34 Congenital malformations of the respiratory system	0.647	0.352
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.647	0.352
Q00-Q07 Congenital malformations of the nervous system	0.647	0.352
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.646	0.353
G56.9 Mononeuropathy of upper limb, unspecified	0.646	0.354
G56.8 Other mononeuropathies of upper limb	0.646	0.354
G56.4 Causalgia	0.646	0.354
G56.3 Lesion of radial nerve	0.646	0.354
G56.1 Other lesions of median nerve	0.646	0.354
T93.2 Sequelae of other fractures of lower limb	0.646	0.354
J92.9 Pleural plaque without asbestos	0.645	0.355
M42 Spinal osteochondrosis	0.644	0.355
M40 Kyphosis and lordosis	0.644	0.355
Z29 Need for other prophylactic measures	0.644	0.355
A48 Other bacterial diseases, not elsewhere classified	0.644	0.356
A44 Bartonellosis	0.644	0.356
A43 Nocardiosis	0.644	0.356
A42 Actinomycosis	0.644	0.356
A40 Streptococcal septicaemia	0.644	0.356
A39 Meningococcal infection	0.644	0.356
A37 Whooping cough	0.644	0.356
A36 Diphtheria	0.644	0.356
A32 Listeriosis	0.644	0.356
A31 Infection due to other mycobacteria	0.644	0.356
A30 Leprosy [Hansen's disease]	0.644	0.356
A38 Scarlet fever	0.644	0.356
A35 Other tetanus	0.644	0.356
A34 Obstetrical tetanus	0.644	0.356
A33 Tetanus neonatorum	0.644	0.356
M43.1 Spondylolisthesis	0.644	0.356
I34 Nonrheumatic mitral valve disorders	0.644	0.356
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.643	0.357
E89.8 Other postprocedural endocrine and metabolic disorders	0.643	0.357
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.643	0.357
E89.5 Postprocedural testicular hypofunction	0.643	0.357
E89.4 Postprocedural ovarian failure	0.643	0.357
E89.2 Postprocedural hypoparathyroidism	0.643	0.357
E89.1 Postprocedural hypoinsulinaemia	0.643	0.357
S79 Other and unspecified injuries of hip and thigh	0.643	0.357
G91 Hydrocephalus	0.643	0.357
J70 Respiratory conditions due to other external agents	0.643	0.357
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.643	0.357
J67 Hypersensitivity pneumonitis due to organic dust	0.643	0.357
J66 Airway disease due to specific organic dust	0.643	0.357
J63 Pneumoconiosis due to other inorganic dusts	0.643	0.357
J62 Pneumoconiosis due to dust containing silica	0.643	0.357
J65 Pneumoconiosis associated with tuberculosis	0.643	0.357
J64 Unspecified pneumoconiosis	0.643	0.357
J60 Coalworker's pneumoconiosis	0.643	0.357
S46 Injury of muscle and tendon at shoulder and upper arm level	0.642	0.358
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.641	0.359
D48.7 Other specified sites	0.641	0.359
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.640	0.360
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.640	0.360
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.640	0.360
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.640	0.360
E83.5 Disorders of calcium metabolism	0.640	0.360
J30.3 Other allergic rhinitis	0.639	0.361
J30.2 Other seasonal allergic rhinitis	0.639	0.361
J30.0 Vasomotor rhinitis	0.639	0.361
S80.9 Superficial injury of lower leg, unspecified	0.639	0.361
M77.9 Enthesopathy, unspecified	0.638	0.362
C50.0 Nipple and areola	0.637	0.363
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.637	0.363
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.636	0.363
S02 Fracture of skull and facial bones	0.636	0.364
R73 Elevated blood glucose level	0.636	0.364
J81 Pulmonary oedema	0.635	0.365
R52 Pain, not elsewhere classified	0.635	0.365
C76 Malignant neoplasm of other and ill-defined sites	0.634	0.365

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations