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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117179684
log Bayes Factor = 20.1477
Chromosome 7   position 12,297,710  (GRCh37) Explore rs117179684 on Ensembl!
Variant rs117179684 is part of Cluster X0256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
F41 Other anxiety disorders
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
F32 Depressive episode
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
M06 Other rheumatoid arthritis
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
F41.9 Anxiety disorder, unspecified
0.989 0.011 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
K70-K77 Diseases of liver
0.984 0.016 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.983 0.017 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.982 0.018 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
M54 Dorsalgia
0.980 0.020 0.000
F32.9 Depressive episode, unspecified
0.971 0.029 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.968 0.032 0.000
B95-B98 Bacterial, viral and other infectious agents
0.966 0.034 0.000
G56 Mononeuropathies of upper limb
0.961 0.039 0.000
L90 Atrophic disorders of skin
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.953 0.047 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.952 0.048 0.000
K70 Alcoholic liver disease
0.950 0.050 0.000
L90.5 Scar conditions and fibrosis of skin
0.950 0.050 0.000
S00-S09 Injuries to the head
0.950 0.050 0.000
H65-H75 Diseases of middle ear and mastoid
0.949 0.051 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.948 0.052 0.000
K50-K52 Noninfective enteritis and colitis
0.948 0.052 0.000
C15-C26 Malignant neoplasms of digestive organs
0.948 0.052 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.946 0.054 0.000
M13 Other arthritis
0.941 0.059 0.000
G90-G99 Other disorders of the nervous system
0.938 0.062 0.000
F32.1 Moderate depressive episode
0.937 0.063 0.000
Chapter XX External causes of morbidity and mortality
0.935 0.065 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.934 0.066 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.931 0.069 0.000
M80-M85 Disorders of bone density and structure
0.927 0.073 0.000
G56.0 Carpal tunnel syndrome
0.927 0.073 0.000
K52 Other non-infective gastro-enteritis and colitis
0.917 0.083 0.000
M54.9 Dorsalgia, unspecified
0.916 0.084 0.000
D00-D09 In situ neoplasms
0.913 0.087 0.000
E70-E90 Metabolic disorders
0.912 0.088 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.910 0.090 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.909 0.091 0.000
F41.2 Mixed anxiety and depressive disorder
0.908 0.092 0.000
H72 Perforation of tympanic membrane
0.905 0.095 0.000
K55-K64 Other diseases of intestines
0.902 0.098 0.000
M13.9 Arthritis, unspecified
0.900 0.100 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.898 0.102 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.889 0.111 0.000
A80-A89 Viral infections of the central nervous system
0.889 0.111 0.000
S20-S29 Injuries to the thorax
0.888 0.112 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.888 0.112 0.000
M07 Psoriatic and enteropathic arthropathies
0.887 0.113 0.000
T51 Toxic effect of alcohol
0.882 0.118 0.000
H90-H95 Other disorders of ear
0.879 0.121 0.000
H80-H83 Diseases of inner ear
0.874 0.126 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.873 0.127 0.000
B25-B34 Other viral diseases
0.869 0.131 0.000
S00 Superficial injury of head
0.867 0.133 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.867 0.133 0.000
L40-L45 Papulosquamous disorders
0.866 0.134 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.865 0.135 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.863 0.137 0.000
D45 Polycythaemia vera
0.863 0.137 0.000
K62 Other diseases of anus and rectum
0.862 0.138 0.000
M51 Other intervertebral disk disorders
0.860 0.140 0.000
Chapter IX Diseases of the circulatory system
0.858 0.142 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.858 0.142 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.856 0.144 0.000
T39.1 4-Aminophenol derivatives
0.856 0.144 0.000
H65 Nonsuppurative otitis media
0.847 0.153 0.000
K70.3 Alcoholic cirrhosis of liver
0.846 0.154 0.000
C34 Malignant neoplasm of bronchus and lung
0.846 0.154 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.845 0.155 0.000
G50 Disorders of trigeminal nerve
0.844 0.156 0.000
K74 Fibrosis and cirrhosis of liver
0.844 0.156 0.000
G40-G47 Episodic and paroxysmal disorders
0.841 0.159 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.840 0.160 0.000
M54.1 Radiculopathy
0.839 0.161 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.839 0.161 0.000
L20-L30 Dermatitis and eczema
0.838 0.162 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.838 0.162 0.000
K35-K38 Diseases of appendix
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.834 0.166 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.829 0.171 0.000
T51.0 Ethanol
0.828 0.172 0.000
X60-X84 Intentional self-harm
0.828 0.172 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.825 0.175 0.000
G93 Other disorders of brain
0.823 0.177 0.000
M81 Osteoporosis without pathological fracture
0.822 0.178 0.000
A00-A09 Intestinal infectious diseases
0.821 0.179 0.000
F33 Recurrent depressive disorder
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.819 0.181 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.818 0.182 0.000
K83 Other diseases of biliary tract
0.817 0.183 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.817 0.183 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.816 0.184 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
F45 Somatoform disorders
0.814 0.186 0.000
S02 Fracture of skull and facial bones
0.814 0.186 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.813 0.187 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.813 0.187 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
K70.9 Alcoholic liver disease, unspecified
0.812 0.188 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.811 0.189 0.000
M54.2 Cervicalgia
0.810 0.189 0.000
M50 Cervical disk disorders
0.809 0.191 0.000
M07.3 Other psoriatic arthropathies
0.807 0.193 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.806 0.194 0.000
E87.2 Acidosis
0.803 0.197 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.803 0.197 0.000
D05 Carcinoma in situ of breast
0.801 0.199 0.000
S70-S79 Injuries to the hip and thigh
0.801 0.199 0.000
C64-C68 Malignant neoplasms of urinary tract
0.801 0.199 0.000
K70.1 Alcoholic hepatitis
0.799 0.201 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.798 0.202 0.000
L40 Psoriasis
0.797 0.203 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.797 0.203 0.000
E87.5 Hyperkalaemia
0.795 0.205 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.795 0.205 0.000
I60-I69 Cerebrovascular diseases
0.794 0.206 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.793 0.206 0.000
M54.5 Low back pain
0.793 0.207 0.000
G56.3 Lesion of radial nerve
0.793 0.207 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.792 0.208 0.000
B15-B19 Viral hepatitis
0.791 0.209 0.000
L50-L54 Urticaria and erythema
0.790 0.210 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.790 0.210 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.790 0.210 0.000
V10-V19 Pedal cyclist injured in transport accident
0.789 0.211 0.000
K85 Acute pancreatitis
0.788 0.212 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.788 0.212 0.000
K81 Cholecystitis
0.788 0.212 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.787 0.213 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
K76 Other diseases of liver
0.787 0.213 0.000
M80 Osteoporosis with pathological fracture
0.785 0.215 0.000
M10 Gout
0.785 0.215 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.784 0.216 0.000
H93 Other disorders of ear, not elsewhere classified
0.783 0.217 0.000
L98.0 Pyogenic granuloma
0.782 0.218 0.000
K40-K46 Hernia
0.781 0.219 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.781 0.219 0.000
M54.3 Sciatica
0.780 0.220 0.000
D06 Carcinoma in situ of cervix uteri
0.779 0.221 0.000
K62.5 Haemorrhage of anus and rectum
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.778 0.222 0.000
K51 Ulcerative colitis
0.775 0.225 0.000
T79-T79 Certain early complications of trauma
0.775 0.225 0.000
M91-M94 Chondropathies
0.775 0.225 0.000
K59 Other functional intestinal disorders
0.774 0.226 0.000
F43 Reaction to severe stress, and adjustment disorders
0.774 0.226 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.774 0.226 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.772 0.228 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.771 0.229 0.000
T85.2 Mechanical complication of intraocular lens
0.768 0.231 0.000
K55 Vascular disorders of intestine
0.768 0.232 0.000
L90.0 Lichen sclerosus et atrophicus
0.767 0.233 0.000
F31 Bipolar affective disorder
0.767 0.233 0.000
G43 Migraine
0.764 0.236 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.764 0.236 0.000
A86 Unspecified viral encephalitis
0.764 0.236 0.000
F32.0 Mild depressive episode
0.763 0.236 0.000
H90 Conductive and sensorineural hearing loss
0.763 0.237 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
B34 Viral infection of unspecified site
0.761 0.239 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.761 0.239 0.000
K62.9 Disease of anus and rectum, unspecified
0.760 0.240 0.000
K42 Umbilical hernia
0.760 0.240 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.760 0.240 0.000
S27 Injury of other and unspecified intrathoracic organs
0.759 0.240 0.000
G90 Disorders of autonomic nervous system
0.759 0.241 0.000
T66-T78 Other and unspecified effects of external causes
0.758 0.242 0.000
T39.0 Salicylates
0.758 0.242 0.000
S05 Injury of eye and orbit
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.756 0.244 0.000
G56.2 Lesion of ulnar nerve
0.756 0.244 0.000
C34.9 Bronchus or lung, unspecified
0.756 0.244 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.754 0.246 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.754 0.246 0.000
G91 Hydrocephalus
0.754 0.246 0.000
M20-M25 Other joint disorders
0.753 0.247 0.000
S00.9 Superficial injury of head, part unspecified
0.753 0.247 0.000
C60-C63 Malignant neoplasms of male genital organs
0.751 0.249 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.750 0.249 0.000
K63 Other diseases of intestine
0.750 0.250 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.748 0.252 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.748 0.252 0.000
F99-F99 Unspecified mental disorder
0.748 0.252 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.747 0.252 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.747 0.253 0.000
C18 Malignant neoplasm of colon
0.747 0.253 0.000
K83.8 Other specified diseases of biliary tract
0.746 0.254 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.746 0.254 0.000
M81.9 Osteoporosis, unspecified
0.746 0.254 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.746 0.254 0.000
G50.0 Trigeminal neuralgia
0.745 0.255 0.000
E20-E35 Disorders of other endocrine glands
0.744 0.256 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.744 0.256 0.000
L40.5 Arthropathic psoriasis
0.744 0.256 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.743 0.257 0.000
C16 Malignant neoplasm of stomach
0.742 0.258 0.000
K74.6 Other and unspecified cirrhosis of liver
0.741 0.259 0.000
K72 Hepatic failure, not elsewhere classified
0.740 0.259 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.740 0.260 0.000
H81 Disorders of vestibular function
0.740 0.260 0.000
G51 Facial nerve disorders
0.740 0.260 0.000
M05 Seropositive rheumatoid arthritis
0.738 0.262 0.000
D38.1 Trachea, bronchus and lung
0.738 0.262 0.000
D41.4 Bladder
0.738 0.262 0.000
A87 Viral meningitis
0.737 0.263 0.000
E00-E07 Disorders of thyroid gland
0.736 0.264 0.000
M45-M49 Spondylopathies
0.736 0.264 0.000
S20 Superficial injury of thorax
0.736 0.264 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.735 0.265 0.000
K35 Acute appendicitis
0.735 0.265 0.000
K70.4 Alcoholic hepatic failure
0.735 0.265 0.000
C21 Malignant neoplasm of anus and anal canal
0.734 0.266 0.000
V40-V49 Car occupant injured in transport accident
0.733 0.267 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.733 0.267 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.733 0.267 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.731 0.269 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.730 0.270 0.000
H65.4 Other chronic nonsuppurative otitis media
0.730 0.270 0.000
M50.2 Other cervical disk displacement
0.729 0.271 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.729 0.271 0.000
E87.0 Hyperosmolality and hypernatraemia
0.729 0.271 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.728 0.272 0.000
M15-M19 Arthrosis
0.727 0.273 0.000
S06 Intracranial injury
0.727 0.273 0.000
K75 Other inflammatory liver diseases
0.726 0.274 0.000
H60-H62 Diseases of external ear
0.726 0.274 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.726 0.274 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.275 0.000
C22.0 Liver cell carcinoma
0.725 0.275 0.000
K52.3 Indeterminate colitis
0.725 0.275 0.000
E10-E14 Diabetes mellitus
0.725 0.275 0.000
D05.1 Intraductal carcinoma in situ
0.723 0.277 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.721 0.279 0.000
I05-I09 Chronic rheumatic heart diseases
0.719 0.281 0.000
E87.6 Hypokalaemia
0.719 0.281 0.000
L93 Lupus erythematosus
0.719 0.281 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.282 0.000
M51.8 Other specified intervertebral disk disorders
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T51.9 Alcohol, unspecified
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.717 0.283 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.716 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
D46 Myelodysplastic syndromes
0.715 0.284 0.000
M06.0 Seronegative rheumatoid arthritis
0.715 0.285 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.715 0.285 0.000
F34 Persistent mood [affective] disorders
0.715 0.285 0.000
F30 Manic episode
0.715 0.285 0.000
F39 Unspecified mood [affective] disorder
0.715 0.285 0.000
F48 Other neurotic disorders
0.715 0.285 0.000
F44 Dissociative [conversion] disorders
0.715 0.285 0.000
F42 Obsessive-compulsive disorder
0.715 0.285 0.000
H93.1 Tinnitus
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
M54.6 Pain in thoracic spine
0.713 0.286 0.000
K62.7 Radiation proctitis
0.713 0.287 0.000
F41.8 Other specified anxiety disorders
0.713 0.287 0.000
F41.3 Other mixed anxiety disorders
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.713 0.287 0.000
F32.8 Other depressive episodes
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.711 0.289 0.000
K82 Other diseases of gallbladder
0.711 0.289 0.000
G58 Other mononeuropathies
0.711 0.289 0.000
H80 Otosclerosis
0.711 0.289 0.000
K59.0 Constipation
0.710 0.290 0.000
M06.8 Other specified rheumatoid arthritis
0.709 0.291 0.000
M06.4 Inflammatory polyarthropathy
0.709 0.291 0.000
M06.3 Rheumatoid nodule
0.709 0.291 0.000
M06.2 Rheumatoid bursitis
0.709 0.291 0.000
M06.1 Adult-onset Still's disease
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
M84 Disorders of continuity of bone
0.709 0.291 0.000
G43.9 Migraine, unspecified
0.708 0.292 0.000
M86-M90 Other osteopathies
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
M19 Other arthrosis
0.707 0.293 0.000
S00.3 Superficial injury of nose
0.706 0.294 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.294 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.294 0.000
K71 Toxic liver disease
0.705 0.294 0.000
D04 Carcinoma in situ of skin
0.705 0.295 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.705 0.295 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.705 0.295 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.705 0.295 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.704 0.296 0.000
G54 Nerve root and plexus disorders
0.704 0.296 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.704 0.296 0.000
G52 Disorders of other cranial nerves
0.704 0.296 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.704 0.296 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.704 0.296 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.704 0.296 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.704 0.296 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.703 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
M54.8 Other dorsalgia
0.703 0.297 0.000
M54.0 Panniculitis affecting regions of neck and back
0.703 0.297 0.000
C20 Malignant neoplasm of rectum
0.702 0.298 0.000
F80-F89 Disorders of psychological development
0.702 0.298 0.000
L85 Other epidermal thickening
0.701 0.298 0.000
M54.57 Low back pain (Lumbosacral region)
0.702 0.298 0.000
I73 Other peripheral vascular diseases
0.700 0.300 0.000
F41.1 Generalised anxiety disorder
0.700 0.300 0.000
D09 Carcinoma in situ of other and unspecified sites
0.699 0.301 0.000
K76.8 Other specified diseases of liver
0.698 0.302 0.000
L29 Pruritus
0.697 0.303 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.697 0.303 0.000
W20-W49 Exposure to inanimate mechanical forces
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
C62 Malignant neoplasm of testis
0.695 0.305 0.000
T86 Failure and rejection of transplanted organs and tissues
0.694 0.306 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.694 0.306 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.694 0.306 0.000
L94 Other localised connective tissue disorders
0.694 0.306 0.000
L87 Transepidermal elimination disorders
0.694 0.306 0.000
L88 Pyoderma gangrenosum
0.694 0.306 0.000
L86 Keratoderma in diseases classified elsewhere
0.694 0.306 0.000
L83 Acanthosis nigricans
0.694 0.306 0.000
L80 Vitiligo
0.694 0.306 0.000
F10.2 Dependence syndrome
0.694 0.306 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.693 0.306 0.000
W00-W19 Falls
0.693 0.307 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.693 0.307 0.000
K55.9 Vascular disorder of intestine, unspecified
0.693 0.307 0.000
C50-C50 Malignant neoplasm of breast
0.692 0.308 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.692 0.308 0.000
C71 Malignant neoplasm of brain
0.690 0.310 0.000
M54.16 Radiculopathy (Lumbar region)
0.690 0.310 0.000
K62.8 Other specified diseases of anus and rectum
0.689 0.311 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.689 0.311 0.000
M54.22 Cervicalgia (Cervical region)
0.689 0.311 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.689 0.311 0.000
G56.8 Other mononeuropathies of upper limb
0.689 0.311 0.000
G56.4 Causalgia
0.689 0.311 0.000
G56.1 Other lesions of median nerve
0.689 0.311 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.689 0.311 0.000
L90.9 Atrophic disorder of skin, unspecified
0.687 0.312 0.000
L90.8 Other atrophic disorders of skin
0.687 0.312 0.000
L90.6 Striae atrophicae
0.687 0.312 0.000
L90.4 Acrodermatitis chronica atrophicans
0.687 0.312 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.687 0.312 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.687 0.312 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.687 0.312 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.687 0.313 0.000
C34.1 Upper lobe, bronchus or lung
0.687 0.313 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.687 0.313 0.000
L84 Corns and callosities
0.687 0.313 0.000
M54.4 Lumbago with sciatica
0.686 0.313 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.686 0.314 0.000
L40.0 Psoriasis vulgaris
0.686 0.314 0.000
G93.5 Compression of brain
0.685 0.314 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.685 0.315 0.000
M11 Other crystal arthropathies
0.685 0.315 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.685 0.315 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.683 0.316 0.000
F45.8 Other somatoform disorders
0.683 0.317 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.683 0.317 0.000
B34.9 Viral infection, unspecified
0.683 0.317 0.000
D06.9 Cervix, unspecified
0.683 0.317 0.000
M19.9 Arthrosis, unspecified
0.682 0.318 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.681 0.319 0.000
K70.0 Alcoholic fatty liver
0.681 0.319 0.000
K85.9 Acute pancreatitis, unspecified
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.681 0.319 0.000
S07 Crushing injury of head
0.681 0.319 0.000
S04 Injury of cranial nerves
0.681 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.681 0.319 0.000
S09 Other and unspecified injuries of head
0.680 0.320 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.680 0.320 0.000
H74 Other disorders of middle ear and mastoid
0.680 0.320 0.000
H70 Mastoiditis and related conditions
0.680 0.320 0.000
H69 Other disorders of Eustachian tube
0.680 0.320 0.000
H68 Eustachian salpingitis and obstruction
0.680 0.320 0.000
H67 Otitis media in diseases classified elsewhere
0.680 0.320 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.680 0.320 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.680 0.320 0.000
G93.0 Cerebral cysts
0.680 0.320 0.000
K63.5 Polyp of colon
0.680 0.320 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.679 0.321 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.679 0.321 0.000
C17 Malignant neoplasm of small intestine
0.679 0.321 0.000
C23 Malignant neoplasm of gallbladder
0.679 0.321 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.679 0.321 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.678 0.322 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.678 0.322 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.678 0.322 0.000
Y57 Other and unspecified drugs and medicaments
0.678 0.322 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.676 0.324 0.000
S51 Open wound of forearm
0.676 0.324 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.675 0.325 0.000
M13.8 Other specified arthritis
0.675 0.325 0.000
M13.1 Monoarthritis, not elsewhere classified
0.675 0.325 0.000
M13.0 Polyarthritis, unspecified
0.675 0.325 0.000
M13.93 Arthritis, unspecified (Forearm)
0.675 0.325 0.000
I74 Arterial embolism and thrombosis
0.673 0.327 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.672 0.328 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.672 0.328 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.672 0.328 0.000
G92 Toxic encephalopathy
0.672 0.328 0.000
G96 Other disorders of central nervous system
0.671 0.329 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.329 0.000
K81.1 Chronic cholecystitis
0.671 0.329 0.000
F10.1 Harmful use
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.670 0.330 0.000
X50-X57 Overexertion, travel and privation
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
W50-W64 Exposure to animate mechanical forces
0.670 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V80-V89 Other land transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
E40-E46 Malnutrition
0.670 0.330 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.670 0.330 0.000
K63.2 Fistula of intestine
0.670 0.330 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.670 0.330 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.670 0.330 0.000
T39.4 Antirheumatics, not elsewhere classified
0.670 0.330 0.000
T39.2 Pyrazolone derivatives
0.670 0.330 0.000
X62.9 Unspecified place
0.669 0.331 0.000
K81.0 Acute cholecystitis
0.669 0.331 0.000
B25 Cytomegaloviral disease
0.669 0.331 0.000
H65.2 Chronic serous otitis media
0.668 0.332 0.000
L28 Lichen simplex chronicus and prurigo
0.668 0.332 0.000
T65 Toxic effect of other and unspecified substances
0.668 0.332 0.000
T63 Toxic effect of contact with venomous animals
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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