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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117411365
log Bayes Factor = 26.5974
Chromosome 18   position 67,468,303  (GRCh37) Explore rs117411365 on Ensembl!
Variant rs117411365 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.997 0.003 0.000
E86 Volume depletion
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.990 0.010 0.000
I20-I25 Ischaemic heart diseases
0.990 0.010 0.000
H02 Other disorders of eyelid
0.986 0.014 0.000
C78.7 Secondary malignant neoplasm of liver
0.985 0.015 0.000
H04 Disorders of lachrymal system
0.981 0.019 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.976 0.024 0.000
I25 Chronic ischaemic heart disease
0.976 0.024 0.000
I60-I69 Cerebrovascular diseases
0.974 0.026 0.000
E00-E07 Disorders of thyroid gland
0.973 0.027 0.000
I05-I09 Chronic rheumatic heart diseases
0.968 0.032 0.000
Z95.1 Presence of aortocoronary bypass graft
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.966 0.034 0.000
S00-S09 Injuries to the head
0.963 0.037 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.959 0.041 0.000
A00-A09 Intestinal infectious diseases
0.955 0.045 0.000
B95-B98 Bacterial, viral and other infectious agents
0.954 0.046 0.000
C78.0 Secondary malignant neoplasm of lung
0.950 0.050 0.000
G20-G26 Extrapyramidal and movement disorders
0.948 0.052 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.944 0.056 0.000
I80 Phlebitis and thrombophlebitis
0.944 0.056 0.000
E03 Other hypothyroidism
0.940 0.060 0.000
T81 Complications of procedures, not elsewhere classified
0.939 0.061 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
I35 Nonrheumatic aortic valve disorders
0.938 0.062 0.000
Z93 Artificial opening status
0.937 0.063 0.000
E10-E14 Diabetes mellitus
0.936 0.064 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.936 0.064 0.000
I25.1 Atherosclerotic heart disease
0.936 0.064 0.000
I08 Multiple valve diseases
0.935 0.065 0.000
A08 Viral and other specified intestinal infections
0.934 0.066 0.000
Z95.4 Presence of other heart-valve replacement
0.932 0.068 0.000
E20-E35 Disorders of other endocrine glands
0.931 0.069 0.000
D00-D09 In situ neoplasms
0.928 0.072 0.000
Z95.2 Presence of prosthetic heart valve
0.926 0.074 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.925 0.075 0.000
S01 Open wound of head
0.922 0.078 0.000
Y83.8 Other surgical procedures
0.922 0.078 0.000
A08.4 Viral intestinal infection, unspecified
0.920 0.080 0.000
I25.2 Old myocardial infarction
0.916 0.084 0.000
E03.9 Hypothyroidism, unspecified
0.916 0.084 0.000
H04.2 Epiphora
0.913 0.087 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.912 0.088 0.000
E11 Non-insulin-dependent diabetes mellitus
0.910 0.090 0.000
I84 Haemorrhoids
0.910 0.090 0.000
I71 Aortic aneurysm and dissection
0.908 0.092 0.000
Z86 Personal history of certain other diseases
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.905 0.095 0.000
H02.4 Ptosis of eyelid
0.904 0.096 0.000
G40-G47 Episodic and paroxysmal disorders
0.900 0.100 0.000
I73 Other peripheral vascular diseases
0.899 0.101 0.000
Z85 Personal history of malignant neoplasm
0.898 0.102 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.898 0.102 0.000
G20 Parkinson's disease
0.896 0.104 0.000
S20-S29 Injuries to the thorax
0.896 0.104 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.894 0.106 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.893 0.107 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.893 0.107 0.000
H02.9 Disorder of eyelid, unspecified
0.893 0.107 0.000
H02.3 Blepharochalasis
0.891 0.108 0.000
E78.0 Pure hypercholesterolaemia
0.888 0.112 0.000
D05 Carcinoma in situ of breast
0.888 0.112 0.000
C15-C26 Malignant neoplasms of digestive organs
0.887 0.113 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.886 0.114 0.000
Z92 Personal history of medical treatment
0.886 0.114 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.886 0.114 0.000
E87.5 Hyperkalaemia
0.885 0.115 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.884 0.116 0.000
Z86.7 Personal history of diseases of the circulatory system
0.881 0.119 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.881 0.119 0.000
C78.2 Secondary malignant neoplasm of pleura
0.879 0.121 0.000
I38 Endocarditis, valve unspecified
0.877 0.123 0.000
I63 Cerebral infarction
0.874 0.126 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.873 0.127 0.000
I50 Heart failure
0.873 0.127 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.867 0.133 0.000
I73.9 Peripheral vascular disease, unspecified
0.864 0.136 0.000
I84.1 Internal haemorrhoids with other complications
0.859 0.141 0.000
G43 Migraine
0.859 0.141 0.000
E87.2 Acidosis
0.854 0.146 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.852 0.148 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.851 0.149 0.000
I62 Other nontraumatic intracranial haemorrhage
0.850 0.150 0.000
E87.6 Hypokalaemia
0.848 0.152 0.000
E06 Thyroiditis
0.847 0.153 0.000
S01.9 Open wound of head, part unspecified
0.846 0.154 0.000
D05.1 Intraductal carcinoma in situ
0.844 0.156 0.000
E83 Disorders of mineral metabolism
0.842 0.158 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.842 0.158 0.000
Z93.2 Ileostomy status
0.840 0.160 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.838 0.162 0.000
I35.0 Aortic (valve) stenosis
0.836 0.164 0.000
Y83.6 Removal of other organ (partial) (total)
0.836 0.164 0.000
D60-D64 Aplastic and other anaemias
0.835 0.165 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.835 0.165 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.834 0.166 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.832 0.168 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.831 0.169 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.829 0.171 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.828 0.172 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.828 0.172 0.000
W00-W19 Falls
0.828 0.172 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.828 0.172 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.827 0.173 0.000
I78 Diseases of capillaries
0.826 0.174 0.000
I95 Hypotension
0.822 0.178 0.000
Chapter X Diseases of the respiratory system
0.822 0.178 0.000
Z95.3 Presence of xenogenic heart valve
0.822 0.178 0.000
I20 Angina pectoris
0.821 0.179 0.000
G43.9 Migraine, unspecified
0.818 0.182 0.000
Y57 Other and unspecified drugs and medicaments
0.815 0.185 0.000
I87 Other disorders of veins
0.815 0.185 0.000
Q60-Q64 Congenital malformations of the urinary system
0.812 0.188 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.812 0.188 0.000
E88 Other metabolic disorders
0.810 0.190 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.810 0.190 0.000
D64 Other anaemias
0.809 0.191 0.000
I35.1 Aortic (valve) insufficiency
0.809 0.191 0.000
I08.0 Disorders of both mitral and aortic valves
0.807 0.193 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.806 0.194 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.806 0.194 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.804 0.196 0.000
E11.4 With neurological complications
0.804 0.196 0.000
I10-I15 Hypertensive diseases
0.803 0.197 0.000
I63.9 Cerebral infarction, unspecified
0.803 0.197 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.803 0.197 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.803 0.197 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.802 0.198 0.000
Z89 Acquired absence of limb
0.802 0.198 0.000
C79 Secondary malignant neoplasm of other sites
0.799 0.201 0.000
I84.2 Internal haemorrhoids without complication
0.798 0.202 0.000
I50.9 Heart failure, unspecified
0.797 0.203 0.000
C80 Malignant neoplasm without specification of site
0.796 0.204 0.000
Z96 Presence of other functional implants
0.796 0.204 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.794 0.206 0.000
G62 Other polyneuropathies
0.794 0.206 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.793 0.207 0.000
I22 Subsequent myocardial infarction
0.792 0.208 0.000
D64.9 Anaemia, unspecified
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.789 0.211 0.000
E27 Other disorders of adrenal gland
0.789 0.211 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.787 0.212 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.785 0.215 0.000
T86 Failure and rejection of transplanted organs and tissues
0.785 0.215 0.000
S02 Fracture of skull and facial bones
0.784 0.216 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.784 0.216 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.784 0.216 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.784 0.216 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.783 0.217 0.000
V20-V29 Motorcycle rider injured in transport accident
0.782 0.218 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.782 0.218 0.000
W20-W49 Exposure to inanimate mechanical forces
0.782 0.218 0.000
E11.9 Without complications
0.779 0.221 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.778 0.222 0.000
H00 Hordeolum and chalazion
0.777 0.223 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.777 0.223 0.000
E28 Ovarian dysfunction
0.775 0.225 0.000
I82 Other venous embolism and thrombosis
0.775 0.225 0.000
C25 Malignant neoplasm of pancreas
0.774 0.226 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.774 0.226 0.000
Y43 Primarily systemic agents
0.773 0.227 0.000
E40-E46 Malnutrition
0.770 0.229 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.769 0.230 0.000
E50-E64 Other nutritional deficiencies
0.767 0.233 0.000
S01.0 Open wound of scalp
0.767 0.233 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.766 0.234 0.000
G95 Other diseases of spinal cord
0.766 0.234 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.766 0.234 0.000
S01.5 Open wound of lip and oral cavity
0.765 0.235 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.764 0.236 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.764 0.236 0.000
I85 Oesophageal varices
0.764 0.236 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.764 0.236 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.761 0.239 0.000
H04.1 Other disorders of lachrymal gland
0.761 0.239 0.000
Z93.0 Tracheostomy status
0.761 0.239 0.000
H02.8 Other specified disorders of eyelid
0.759 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.759 0.241 0.000
C51-C58 Malignant neoplasms of female genital organs
0.758 0.242 0.000
E06.3 Autoimmune thyroiditis
0.757 0.243 0.000
I61 Intracerebral haemorrhage
0.756 0.244 0.000
S80-S89 Injuries to the knee and lower leg
0.756 0.244 0.000
Y52 Agents primarily affecting the cardiovascular system
0.755 0.245 0.000
E11.5 With peripheral circulatory complications
0.755 0.245 0.000
I37 Pulmonary valve disorders
0.754 0.246 0.000
Q61 Cystic kidney disease
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.753 0.247 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.752 0.248 0.000
E22 Hyperfunction of pituitary gland
0.751 0.249 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.751 0.249 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.751 0.249 0.000
I05 Rheumatic mitral valve diseases
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.750 0.250 0.000
I86 Varicose veins of other sites
0.750 0.250 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.749 0.251 0.000
H10-H13 Disorders of conjunctiva
0.749 0.251 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.749 0.251 0.000
I84.4 External haemorrhoids with other complications
0.748 0.252 0.000
I95.1 Orthostatic hypotension
0.748 0.252 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.747 0.253 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.747 0.253 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.746 0.254 0.000
S90-S99 Injuries to the ankle and foot
0.745 0.255 0.000
G81 Hemiplegia
0.744 0.256 0.000
E11.6 With other specified complications
0.744 0.256 0.000
G82 Paraplegia and tetraplegia
0.744 0.256 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.743 0.257 0.000
Z93.6 Other artificial openings of urinary tract status
0.743 0.257 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.743 0.257 0.000
Z92.8 Personal history of other medical treatment
0.742 0.257 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.742 0.258 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.742 0.258 0.000
Y40 Systemic antibiotics
0.741 0.259 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.740 0.260 0.000
G44 Other headache syndromes
0.740 0.260 0.000
D45 Polycythaemia vera
0.738 0.262 0.000
E23 Hypofunction and other disorders of pituitary gland
0.737 0.263 0.000
V80-V89 Other land transport accidents
0.736 0.264 0.000
A80-A89 Viral infections of the central nervous system
0.735 0.264 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.735 0.264 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.733 0.267 0.000
I07 Rheumatic tricuspid valve diseases
0.733 0.267 0.000
I12 Hypertensive renal disease
0.732 0.268 0.000
G24 Dystonia
0.731 0.269 0.000
W06 Fall involving bed
0.729 0.271 0.000
I51 Complications and ill-defined descriptions of heart disease
0.728 0.272 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.727 0.273 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.727 0.273 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.726 0.274 0.000
S01.1 Open wound of eyelid and periocular area
0.726 0.274 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.726 0.274 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.726 0.274 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.725 0.275 0.000
I70 Atherosclerosis
0.725 0.275 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.725 0.275 0.000
H53-H54 Visual disturbances and blindness
0.724 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
Z96.0 Presence of urogenital implants
0.724 0.276 0.000
L03 Cellulitis
0.723 0.277 0.000
Y57.9 Drug or medicament, unspecified
0.723 0.277 0.000
B15-B19 Viral hepatitis
0.723 0.277 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.722 0.278 0.000
Z93.5 Cystostomy status
0.721 0.278 0.000
I33 Acute and subacute endocarditis
0.721 0.279 0.000
H02.1 Ectropion of eyelid
0.720 0.280 0.000
G25 Other extrapyramidal and movement disorders
0.720 0.280 0.000
I72 Other aneurysm
0.719 0.280 0.000
S27 Injury of other and unspecified intrathoracic organs
0.718 0.282 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.718 0.282 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.718 0.282 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
S06 Intracranial injury
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
Z83 Family history of other specific disorders
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
S20 Superficial injury of thorax
0.715 0.285 0.000
H05 Disorders of orbit
0.715 0.285 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.715 0.285 0.000
I71.0 Dissection of aorta [any part]
0.714 0.286 0.000
E83.1 Disorders of iron metabolism
0.714 0.286 0.000
S60-S69 Injuries to the wrist and hand
0.714 0.286 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
Z57 Occupational exposure to risk-factors
0.712 0.288 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.712 0.288 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
I25.5 Ischaemic cardiomyopathy
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
T66-T78 Other and unspecified effects of external causes
0.710 0.289 0.000
I88 Nonspecific lymphadenitis
0.710 0.290 0.000
I81 Portal vein thrombosis
0.710 0.290 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.709 0.291 0.000
Z90.3 Acquired absence of part of stomach
0.709 0.291 0.000
I84.9 Unspecified haemorrhoids without complication
0.709 0.291 0.000
C91 Lymphoid leukaemia
0.708 0.292 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.707 0.293 0.000
G93 Other disorders of brain
0.707 0.293 0.000
T39.1 4-Aminophenol derivatives
0.707 0.293 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.707 0.293 0.000
H02.6 Xanthelasma of eyelid
0.707 0.293 0.000
H02.5 Other disorders affecting eyelid function
0.707 0.293 0.000
H02.2 Lagophthalmos
0.707 0.293 0.000
Y83.3 Surgical operation with formation of external stoma
0.706 0.294 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.705 0.295 0.000
Y44 Agents primarily affecting blood constituents
0.704 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.704 0.296 0.000
S09 Other and unspecified injuries of head
0.704 0.296 0.000
H04.9 Disorder of lachrymal system, unspecified
0.704 0.296 0.000
H04.8 Other disorders of lachrymal system
0.704 0.296 0.000
H04.6 Other changes in lachrymal passages
0.704 0.296 0.000
H04.4 Chronic inflammation of lachrymal passages
0.704 0.296 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.704 0.296 0.000
H04.0 Dacryoadenitis
0.704 0.296 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.702 0.298 0.000
E87.4 Mixed disorder of acid-base balance
0.702 0.298 0.000
E87.3 Alkalosis
0.702 0.298 0.000
E87.0 Hyperosmolality and hypernatraemia
0.702 0.298 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.702 0.298 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.700 0.300 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.700 0.300 0.000
I25.4 Coronary artery aneurysm
0.700 0.300 0.000
I25.3 Aneurysm of heart
0.700 0.300 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.699 0.301 0.000
C92 Myeloid leukaemia
0.699 0.301 0.000
I63.8 Other cerebral infarction
0.698 0.302 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.698 0.302 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.698 0.302 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.698 0.302 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.698 0.302 0.000
E00 Congenital iodine-deficiency syndrome
0.698 0.302 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.698 0.302 0.000
S32 Fracture of lumbar spine and pelvis
0.697 0.303 0.000
G62.9 Polyneuropathy, unspecified
0.697 0.303 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.696 0.303 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.696 0.304 0.000
Z99.3 Dependence on wheelchair
0.695 0.305 0.000
Z93.3 Colostomy status
0.694 0.306 0.000
I09 Other rheumatic heart diseases
0.694 0.306 0.000
I06 Rheumatic aortic valve diseases
0.694 0.306 0.000
G95.2 Cord compression, unspecified
0.694 0.306 0.000
C20 Malignant neoplasm of rectum
0.694 0.306 0.000
I21 Acute myocardial infarction
0.694 0.306 0.000
D04 Carcinoma in situ of skin
0.694 0.306 0.000
H55-H59 Other disorders of eye and adnexa
0.694 0.306 0.000
C18 Malignant neoplasm of colon
0.693 0.307 0.000
I52 Other heart disorders in diseases classified elsewhere
0.693 0.307 0.000
I48 Atrial fibrillation and flutter
0.693 0.307 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.693 0.307 0.000
I41 Myocarditis in diseases classified elsewhere
0.693 0.307 0.000
I40 Acute myocarditis
0.693 0.307 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.693 0.307 0.000
I36 Nonrheumatic tricuspid valve disorders
0.693 0.307 0.000
I32 Pericarditis in diseases classified elsewhere
0.693 0.307 0.000
I30 Acute pericarditis
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.692 0.308 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.692 0.308 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.692 0.308 0.000
C15 Malignant neoplasm of oesophagus
0.692 0.308 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.691 0.309 0.000
I50.0 Congestive heart failure
0.691 0.309 0.000
Z63 Other problems related to primary support group, including family circumstances
0.690 0.310 0.000
S08 Traumatic amputation of part of head
0.690 0.310 0.000
S07 Crushing injury of head
0.690 0.310 0.000
S05 Injury of eye and orbit
0.690 0.310 0.000
S04 Injury of cranial nerves
0.690 0.310 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.310 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.690 0.310 0.000
J90-J94 Other diseases of pleura
0.690 0.310 0.000
Z43 Attention to artificial openings
0.690 0.310 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.690 0.310 0.000
H18 Other disorders of cornea
0.689 0.310 0.000
I12.0 Hypertensive renal disease with renal failure
0.688 0.312 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.688 0.312 0.000
I24 Other acute ischaemic heart diseases
0.687 0.313 0.000
C50-C50 Malignant neoplasm of breast
0.687 0.313 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.686 0.314 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.686 0.314 0.000
T82.3 Mechanical complication of other vascular grafts
0.685 0.314 0.000
D03 Melanoma in situ
0.685 0.315 0.000
Q50-Q56 Congenital malformations of genital organs
0.685 0.315 0.000
A07 Other protozoal intestinal diseases
0.685 0.315 0.000
A06 Amoebiasis
0.685 0.315 0.000
A05 Other bacterial foodborne intoxications
0.685 0.315 0.000
A03 Shigellosis
0.685 0.315 0.000
A02 Other Salmonella infections
0.685 0.315 0.000
A01 Typhoid and paratyphoid fevers
0.685 0.315 0.000
A00 Cholera
0.685 0.315 0.000
I84.5 External haemorrhoids without complication
0.681 0.319 0.000
G43.1 Migraine with aura [classical migraine]
0.681 0.319 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.680 0.320 0.000
A04 Other bacterial intestinal infections
0.680 0.320 0.000
Z60 Problems related to social environment
0.680 0.320 0.000
G23 Other degenerative diseases of basal ganglia
0.679 0.320 0.000
G21 Secondary Parkinsonism
0.679 0.320 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.679 0.320 0.000
G22 Parkinsonism in diseases classified elsewhere
0.679 0.320 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.679 0.321 0.000
E11.3 With ophthalmic complications
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.323 0.000
Y58 Bacterial vaccines
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.323 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.323 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.323 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.323 0.000
W17 Other fall from one level to another
0.677 0.323 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.677 0.323 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.677 0.323 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.677 0.323 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.677 0.323 0.000
Y95 Nosocomial condition
0.677 0.323 0.000
D55-D59 Haemolytic anaemias
0.676 0.324 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.676 0.324 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.675 0.325 0.000
G90 Disorders of autonomic nervous system
0.674 0.326 0.000
Chapter VIII Diseases of the ear and mastoid process
0.674 0.326 0.000
E03.8 Other specified hypothyroidism
0.674 0.326 0.000
E03.5 Myxoedema coma
0.674 0.326 0.000
E03.4 Atrophy of thyroid (acquired)
0.674 0.326 0.000
E03.3 Postinfectious hypothyroidism
0.674 0.326 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.674 0.326 0.000
E03.1 Congenital hypothyroidism without goitre
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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