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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117504245
log Bayes Factor = 13.128
Chromosome 18   position 32,214,484  (GRCh37) Explore rs117504245 on Ensembl!
Variant rs117504245 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.995 0.005 0.000
G90-G99 Other disorders of the nervous system
0.984 0.016 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.981 0.019 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.979 0.021 0.000
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.977 0.023 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
C78.7 Secondary malignant neoplasm of liver
0.975 0.025 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.974 0.026 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.959 0.041 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.957 0.043 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.953 0.047 0.000
W00-W19 Falls
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.943 0.057 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.943 0.057 0.000
J00-J06 Acute upper respiratory infections
0.938 0.062 0.000
J09-J18 Influenza and pneumonia
0.937 0.063 0.000
J90-J94 Other diseases of pleura
0.935 0.065 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.935 0.065 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.932 0.068 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.928 0.072 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.923 0.077 0.000
S06 Intracranial injury
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.921 0.079 0.000
C34 Malignant neoplasm of bronchus and lung
0.920 0.080 0.000
C77.3 Axillary and upper limb lymph nodes
0.919 0.081 0.000
W19 Unspecified fall
0.914 0.086 0.000
D70 Agranulocytosis
0.912 0.088 0.000
C91 Lymphoid leukaemia
0.905 0.095 0.000
J90 Pleural effusion, not elsewhere classified
0.901 0.099 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.897 0.103 0.000
H10-H13 Disorders of conjunctiva
0.896 0.104 0.000
D80-D89 Certain disorders involving the immune mechanism
0.893 0.107 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.892 0.108 0.000
C78.0 Secondary malignant neoplasm of lung
0.891 0.109 0.000
C92 Myeloid leukaemia
0.889 0.111 0.000
C20 Malignant neoplasm of rectum
0.883 0.117 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.880 0.120 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.870 0.130 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.867 0.133 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
G62 Other polyneuropathies
0.865 0.135 0.000
G35 Multiple sclerosis
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.862 0.138 0.000
W19.9 Unspecified place
0.858 0.142 0.000
Chapter I Certain infectious and parasitic diseases
0.858 0.142 0.000
G93 Other disorders of brain
0.858 0.142 0.000
M70-M79 Other soft tissue disorders
0.858 0.142 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.857 0.143 0.000
J30-J39 Other diseases of upper respiratory tract
0.855 0.145 0.000
C91.1 Chronic lymphocytic leukaemia
0.855 0.145 0.000
J18 Pneumonia, organism unspecified
0.853 0.147 0.000
Y43 Primarily systemic agents
0.853 0.147 0.000
H55-H59 Other disorders of eye and adnexa
0.849 0.151 0.000
G91 Hydrocephalus
0.847 0.153 0.000
C18 Malignant neoplasm of colon
0.845 0.155 0.000
Chapter V Mental and behavioural disorders
0.843 0.157 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.843 0.157 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.840 0.160 0.000
J06.9 Acute upper respiratory infection, unspecified
0.839 0.161 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.839 0.161 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.839 0.161 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.837 0.163 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.837 0.163 0.000
H01 Other inflammation of eyelid
0.836 0.164 0.000
S06.5 Traumatic subdural haemorrhage
0.836 0.164 0.000
H11 Other disorders of conjunctiva
0.835 0.165 0.000
G20-G26 Extrapyramidal and movement disorders
0.834 0.166 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.834 0.166 0.000
G30-G32 Other degenerative diseases of the nervous system
0.832 0.168 0.000
G96 Other disorders of central nervous system
0.831 0.168 0.000
S02 Fracture of skull and facial bones
0.829 0.171 0.000
C77.1 Intrathoracic lymph nodes
0.828 0.172 0.000
S00 Superficial injury of head
0.826 0.174 0.000
M05-M14 Inflammatory polyarthropathies
0.824 0.176 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.818 0.182 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.818 0.182 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.818 0.182 0.000
C34.3 Lower lobe, bronchus or lung
0.811 0.189 0.000
A30-A49 Other bacterial diseases
0.811 0.189 0.000
G62.9 Polyneuropathy, unspecified
0.811 0.189 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.809 0.191 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.809 0.191 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.809 0.191 0.000
W19.4 Street and highway
0.807 0.193 0.000
C77.2 Intra-abdominal lymph nodes
0.804 0.196 0.000
S01 Open wound of head
0.803 0.197 0.000
C34.1 Upper lobe, bronchus or lung
0.802 0.198 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.800 0.200 0.000
J34 Other disorders of nose and nasal sinuses
0.798 0.202 0.000
M80-M85 Disorders of bone density and structure
0.796 0.204 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.796 0.204 0.000
H01.0 Blepharitis
0.796 0.204 0.000
G70-G73 Diseases of myoneural junction and muscle
0.796 0.204 0.000
C92.0 Acute myeloid leukaemia
0.794 0.206 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.792 0.208 0.000
D86 Sarcoidosis
0.791 0.209 0.000
G95 Other diseases of spinal cord
0.789 0.211 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.787 0.213 0.000
F41 Other anxiety disorders
0.787 0.213 0.000
D73 Diseases of spleen
0.780 0.220 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.779 0.221 0.000
Y43.3 Other antineoplastic drugs
0.779 0.221 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.775 0.225 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.775 0.225 0.000
F41.2 Mixed anxiety and depressive disorder
0.774 0.226 0.000
J03 Acute tonsillitis
0.774 0.226 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.773 0.227 0.000
J84 Other interstitial pulmonary diseases
0.772 0.228 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.772 0.228 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.772 0.228 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.771 0.229 0.000
D00-D09 In situ neoplasms
0.769 0.231 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.769 0.231 0.000
M10 Gout
0.767 0.233 0.000
C34.9 Bronchus or lung, unspecified
0.766 0.234 0.000
A41 Other septicaemia
0.765 0.235 0.000
C77.0 Lymph nodes of head, face and neck
0.764 0.235 0.000
C78.2 Secondary malignant neoplasm of pleura
0.764 0.236 0.000
D60-D64 Aplastic and other anaemias
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.761 0.239 0.000
H52 Disorders of refraction and accommodation
0.761 0.239 0.000
S06.0 Concussion
0.760 0.239 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.760 0.240 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.759 0.241 0.000
G93.8 Other specified disorders of brain
0.759 0.241 0.000
J18.9 Pneumonia, unspecified
0.758 0.242 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.754 0.245 0.000
T86 Failure and rejection of transplanted organs and tissues
0.754 0.246 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.752 0.248 0.000
C77.4 Inguinal and lower limb lymph nodes
0.752 0.248 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.749 0.251 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.749 0.251 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.748 0.251 0.000
V40-V49 Car occupant injured in transport accident
0.746 0.254 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.746 0.254 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.744 0.256 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.742 0.258 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.742 0.258 0.000
A41.9 Septicaemia, unspecified
0.741 0.259 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.741 0.259 0.000
H57 Other disorders of eye and adnexa
0.740 0.260 0.000
Y52 Agents primarily affecting the cardiovascular system
0.739 0.261 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.739 0.261 0.000
G40-G47 Episodic and paroxysmal disorders
0.737 0.262 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.737 0.263 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.737 0.263 0.000
S60-S69 Injuries to the wrist and hand
0.737 0.263 0.000
J18.1 Lobar pneumonia, unspecified
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.736 0.264 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.734 0.266 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.734 0.266 0.000
S10-S19 Injuries to the neck
0.734 0.266 0.000
M75 Shoulder lesions
0.733 0.267 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.733 0.267 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.732 0.268 0.000
C92.1 Chronic myeloid leukaemia
0.729 0.271 0.000
T90 Sequelae of injuries of head
0.728 0.272 0.000
H40-H42 Glaucoma
0.728 0.272 0.000
J92 Pleural plaque
0.727 0.273 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.727 0.273 0.000
M10.9 Gout, unspecified
0.726 0.274 0.000
J01 Acute sinusitis
0.723 0.277 0.000
W13 Fall from, out of or through building or structure
0.722 0.278 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.721 0.279 0.000
W19.3 Sports and athletics area
0.721 0.279 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.721 0.279 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.283 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.716 0.284 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.716 0.284 0.000
Chapter VIII Diseases of the ear and mastoid process
0.715 0.285 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.715 0.285 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.714 0.285 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.714 0.286 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.714 0.286 0.000
J20-J22 Other acute lower respiratory infections
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.714 0.286 0.000
T92 Sequelae of injuries of upper limb
0.713 0.287 0.000
C71 Malignant neoplasm of brain
0.713 0.287 0.000
H30-H36 Disorders of choroid and retina
0.713 0.287 0.000
T81 Complications of procedures, not elsewhere classified
0.713 0.287 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
C51-C58 Malignant neoplasms of female genital organs
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.708 0.292 0.000
J80 Adult respiratory distress syndrome
0.708 0.292 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.708 0.292 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.707 0.293 0.000
T85.2 Mechanical complication of intraocular lens
0.707 0.293 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.293 0.000
C25 Malignant neoplasm of pancreas
0.706 0.294 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.706 0.294 0.000
Q60-Q64 Congenital malformations of the urinary system
0.706 0.294 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.706 0.294 0.000
G90 Disorders of autonomic nervous system
0.706 0.294 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
G92 Toxic encephalopathy
0.706 0.294 0.000
S40-S49 Injuries to the shoulder and upper arm
0.705 0.295 0.000
C34.0 Main bronchus
0.704 0.296 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.298 0.000
C77.8 Lymph nodes of multiple regions
0.702 0.298 0.000
C77.9 Lymph node, unspecified
0.702 0.298 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.701 0.299 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.701 0.299 0.000
C21 Malignant neoplasm of anus and anal canal
0.701 0.299 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
C23 Malignant neoplasm of gallbladder
0.701 0.299 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
G60 Hereditary and idiopathic neuropathy
0.700 0.299 0.000
T66-T78 Other and unspecified effects of external causes
0.700 0.300 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.301 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
C95 Leukaemia of unspecified cell type
0.698 0.302 0.000
C94 Other leukaemias of specified cell type
0.698 0.302 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
C88 Malignant immunoproliferative diseases
0.698 0.302 0.000
C86 Other specified types of T/NK-cell lymphoma
0.698 0.302 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.698 0.302 0.000
D86.0 Sarcoidosis of lung
0.698 0.302 0.000
C50-C50 Malignant neoplasm of breast
0.698 0.302 0.000
S02.4 Fracture of malar and maxillary bones
0.696 0.304 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.696 0.304 0.000
H05 Disorders of orbit
0.695 0.305 0.000
Y43.4 Immunosuppressive agents
0.695 0.305 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.695 0.305 0.000
C18.5 Splenic flexure
0.695 0.305 0.000
G91.1 Obstructive hydrocephalus
0.694 0.306 0.000
C18.9 Colon, unspecified
0.694 0.306 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.694 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.307 0.000
M00-M03 Infectious arthropathies
0.692 0.307 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.692 0.308 0.000
S06.3 Focal brain injury
0.692 0.308 0.000
G91.9 Hydrocephalus, unspecified
0.691 0.309 0.000
S06.2 Diffuse brain injury
0.691 0.309 0.000
J94 Other pleural conditions
0.690 0.310 0.000
G25 Other extrapyramidal and movement disorders
0.690 0.310 0.000
D72 Other disorders of white blood cells
0.689 0.310 0.000
C81 Hodgkin's disease
0.689 0.311 0.000
S01.3 Open wound of ear
0.688 0.312 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.687 0.312 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.687 0.312 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.687 0.312 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.687 0.313 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.687 0.313 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.687 0.313 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.687 0.313 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.686 0.313 0.000
M91-M94 Chondropathies
0.686 0.314 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.686 0.314 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.686 0.314 0.000
H11.8 Other specified disorders of conjunctiva
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.683 0.316 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.683 0.316 0.000
C32 Malignant neoplasm of larynx
0.683 0.316 0.000
C31 Malignant neoplasm of accessory sinuses
0.683 0.316 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.683 0.316 0.000
C37 Malignant neoplasm of thymus
0.683 0.316 0.000
C33 Malignant neoplasm of trachea
0.683 0.316 0.000
M13 Other arthritis
0.684 0.316 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
V20-V29 Motorcycle rider injured in transport accident
0.682 0.318 0.000
G37 Other demyelinating diseases of central nervous system
0.682 0.318 0.000
M20-M25 Other joint disorders
0.681 0.319 0.000
M71 Other bursopathies
0.681 0.319 0.000
C18.2 Ascending colon
0.681 0.319 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.680 0.320 0.000
C18.6 Descending colon
0.679 0.321 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
W18 Other fall on same level
0.676 0.323 0.000
W17 Other fall from one level to another
0.676 0.323 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.676 0.323 0.000
W15 Fall from cliff
0.676 0.323 0.000
W14 Fall from tree
0.676 0.323 0.000
W12 Fall on and from scaffolding
0.676 0.323 0.000
W11 Fall on and from ladder
0.676 0.323 0.000
W10 Fall on and from stairs and steps
0.676 0.323 0.000
W09 Fall involving playground equipment
0.676 0.323 0.000
W08 Fall involving other furniture
0.676 0.323 0.000
W05 Fall involving wheelchair
0.676 0.323 0.000
W04 Fall while being carried or supported by other persons
0.676 0.323 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.676 0.323 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.676 0.323 0.000
W00 Fall on same level involving ice and snow
0.676 0.323 0.000
C79.6 Secondary malignant neoplasm of ovary
0.676 0.323 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.676 0.323 0.000
C79.2 Secondary malignant neoplasm of skin
0.676 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.676 0.323 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.676 0.323 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.676 0.324 0.000
D74 Methaemoglobinaemia
0.676 0.324 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.676 0.324 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.676 0.324 0.000
G80 Infantile cerebral palsy
0.676 0.324 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.673 0.327 0.000
J04 Acute laryngitis and tracheitis
0.673 0.327 0.000
J17 Pneumonia in diseases classified elsewhere
0.672 0.328 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.672 0.328 0.000
J12 Viral pneumonia, not elsewhere classified
0.672 0.328 0.000
J11 Influenza, virus not identified
0.672 0.328 0.000
J10 Influenza due to identified influenza virus
0.672 0.328 0.000
J14 Pneumonia due to Haemophilus influenzae
0.672 0.328 0.000
J09 Influenza due to certain identified influenza virus
0.672 0.328 0.000
G93.6 Cerebral oedema
0.672 0.328 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
G61 Inflammatory polyneuropathy
0.671 0.329 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.670 0.330 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.670 0.330 0.000
T83.2 Mechanical complication of graft of urinary organ
0.670 0.330 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.670 0.330 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.669 0.331 0.000
C22.0 Liver cell carcinoma
0.669 0.331 0.000
C07 Malignant neoplasm of parotid gland
0.668 0.331 0.000
J35 Chronic diseases of tonsils and adenoids
0.668 0.332 0.000
G64 Other disorders of peripheral nervous system
0.668 0.332 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.668 0.332 0.000
W06 Fall involving bed
0.667 0.333 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.667 0.333 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.666 0.334 0.000
M60-M63 Disorders of muscles
0.665 0.334 0.000
M86-M90 Other osteopathies
0.663 0.337 0.000
G83 Other paralytic syndromes
0.663 0.337 0.000
D73.0 Hyposplenism
0.663 0.337 0.000
C77.5 Intrapelvic lymph nodes
0.662 0.338 0.000
G36 Other acute disseminated demyelination
0.661 0.338 0.000
S06.9 Intracranial injury, unspecified
0.660 0.340 0.000
S06.8 Other intracranial injuries
0.660 0.340 0.000
S06.7 Intracranial injury with prolonged coma
0.660 0.340 0.000
S06.4 Epidural haemorrhage
0.660 0.340 0.000
S06.1 Traumatic cerebral oedema
0.660 0.340 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y48 Anaesthetics and therapeutic gases
0.660 0.340 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
H52.0 Hypermetropia
0.660 0.340 0.000
H11.9 Disorder of conjunctiva, unspecified
0.660 0.340 0.000
C34.8 Overlapping lesion of bronchus and lung
0.660 0.340 0.000
C34.2 Middle lobe, bronchus or lung
0.660 0.340 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.658 0.342 0.000
J60-J70 Lung diseases due to external agents
0.658 0.342 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.657 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.656 0.343 0.000
J03.9 Acute tonsillitis, unspecified
0.656 0.344 0.000
W19.8 Other specified place
0.655 0.344 0.000
W19.5 Trade and service area
0.655 0.344 0.000
W19.0 Home
0.655 0.344 0.000
W19.7 Farm
0.655 0.344 0.000
W19.6 Industrial and construction area
0.655 0.344 0.000
W19.1 Residential institution
0.655 0.344 0.000
J32 Chronic sinusitis
0.655 0.345 0.000
M85 Other disorders of bone density and structure
0.654 0.346 0.000
T88.5 Other complications of anaesthesia
0.653 0.347 0.000
A40 Streptococcal septicaemia
0.650 0.350 0.000
S00.9 Superficial injury of head, part unspecified
0.650 0.350 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.650 0.350 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.650 0.350 0.000
C91.9 Lymphoid leukaemia, unspecified
0.648 0.351 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.648 0.351 0.000
C91.7 Other lymphoid leukaemia
0.648 0.351 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.648 0.351 0.000
C91.5 Adult T-cell leukaemia
0.648 0.351 0.000
C91.4 Hairy-cell leukaemia
0.648 0.351 0.000
C91.3 Prolymphocytic leukaemia
0.648 0.351 0.000
C91.2 Subacute lymphocytic leukaemia
0.648 0.351 0.000
C91.0 Acute lymphoblastic leukaemia
0.648 0.351 0.000
Y57 Other and unspecified drugs and medicaments
0.648 0.351 0.000
H43-H45 Disorders of vitreous body and globe
0.648 0.351 0.000
S06.00 Concussion (without open intracranial wound)
0.646 0.354 0.000
G62.8 Other specified polyneuropathies
0.645 0.355 0.000
J37 Chronic laryngitis and laryngotracheitis
0.645 0.355 0.000
O32.1 Maternal care for breech presentation
0.644 0.356 0.000
S00.8 Superficial injury of other parts of head
0.644 0.356 0.000
W07 Fall involving chair
0.644 0.356 0.000
F99-F99 Unspecified mental disorder
0.644 0.356 0.000
W20-W49 Exposure to inanimate mechanical forces
0.643 0.357 0.000
J15.4 Pneumonia due to other streptococci
0.643 0.357 0.000
M10.99 Gout, unspecified (Site unspecified)
0.643 0.357 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.643 0.357 0.000
H53-H54 Visual disturbances and blindness
0.642 0.358 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.642 0.358 0.000
G95.9 Disease of spinal cord, unspecified
0.641 0.359 0.000
D84 Other immunodeficiencies
0.640 0.360 0.000
D83 Common variable immunodeficiency
0.640 0.360 0.000
D82 Immunodeficiency associated with other major defects
0.640 0.360 0.000
D81 Combined immunodeficiencies
0.640 0.360 0.000
D80 Immunodeficiency with predominantly antibody defects
0.640 0.360 0.000
O36 Maternal care for other known or suspected foetal problems
0.640 0.360 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.640 0.360 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.639 0.361 0.000
X60-X84 Intentional self-harm
0.638 0.362 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.638 0.362 0.000
C92.9 Myeloid leukaemia, unspecified
0.638 0.362 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.638 0.362 0.000
C92.7 Other myeloid leukaemia
0.638 0.362 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.638 0.362 0.000
C92.5 Acute myelomonocytic leukaemia
0.638 0.362 0.000
C92.4 Acute promyelocytic leukaemia
0.638 0.362 0.000
C92.3 Myeloid sarcoma
0.638 0.362 0.000
C92.2 Subacute myeloid leukaemia
0.638 0.362 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.637 0.363 0.000
S00.0 Superficial injury of scalp
0.636 0.364 0.000
H55 Nystagmus and other irregular eye movements
0.636 0.364 0.000
M75.0 Adhesive capsulitis of shoulder
0.635 0.365 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.634 0.366 0.000
B07 Viral warts
0.633 0.367 0.000
S01.0 Open wound of scalp
0.633 0.367 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.633 0.367 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.632 0.367 0.000
H10 Conjunctivitis
0.632 0.368 0.000
J95-J99 Other diseases of the respiratory system
0.632 0.368 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.631 0.369 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.631 0.369 0.000
J06.0 Acute laryngopharyngitis
0.631 0.369 0.000
D04 Carcinoma in situ of skin
0.631 0.369 0.000
J02 Acute pharyngitis
0.631 0.369 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.631 0.369 0.000
G43 Migraine
0.630 0.370 0.000
C90.0 Multiple myeloma
0.629 0.370 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.629 0.370 0.000
S02.5 Fracture of tooth
0.629 0.371 0.000
M80 Osteoporosis with pathological fracture
0.629 0.371 0.000
M77 Other enthesopathies
0.628 0.372 0.000
C16 Malignant neoplasm of stomach
0.628 0.372 0.000
S80-S89 Injuries to the knee and lower leg
0.628 0.372 0.000
Y49.2 Other and unspecified antidepressants
0.627 0.373 0.000
G96.0 Cerebrospinal fluid leak
0.626 0.374 0.000
G20 Parkinson's disease
0.626 0.374 0.000
G71 Primary disorders of muscles
0.626 0.374 0.000
H50 Other strabismus
0.626 0.374 0.000
S32 Fracture of lumbar spine and pelvis
0.625 0.375 0.000
M84 Disorders of continuity of bone
0.625 0.375 0.000
S20 Superficial injury of thorax
0.624 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.624 0.376 0.000
Q80-Q89 Other congenital malformations
0.624 0.376 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.624 0.376 0.000
Q35-Q37 Cleft lip and cleft palate
0.624 0.376 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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