TreeWAS – Variant ID: rs11758000

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
Chapter V Mental and behavioural disorders	0.995	0.005
Chapter VII Diseases of the eye and adnexa	0.994	0.006
S80-S89 Injuries to the knee and lower leg	0.994	0.006
N17-N19 Renal failure	0.992	0.008
Chapter VI Diseases of the nervous system	0.986	0.014
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.978	0.022
E65-E68 Obesity and other hyperalimentation	0.977	0.023
N19 Unspecified renal failure	0.975	0.025
E66 Obesity	0.964	0.036
Chapter X Diseases of the respiratory system	0.963	0.037
H40-H42 Glaucoma	0.956	0.044
N18 Chronic renal failure	0.954	0.046
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.954	0.046
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.951	0.049
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.951	0.049
M70-M79 Other soft tissue disorders	0.950	0.050
H30-H36 Disorders of choroid and retina	0.942	0.058
E66.8 Other obesity	0.937	0.063
S82 Fracture of lower leg, including ankle	0.937	0.063
N10-N16 Renal tubulo-interstitial diseases	0.934	0.066
F30-F39 Mood [affective] disorders	0.934	0.066
M65-M68 Disorders of synovium and tendon	0.933	0.067
N25-N29 Other disorders of kidney and ureter	0.930	0.070
H40 Glaucoma	0.928	0.072
T39.1 4-Aminophenol derivatives	0.928	0.072
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.927	0.073
M05-M14 Inflammatory polyarthropathies	0.926	0.074
J09-J18 Influenza and pneumonia	0.922	0.078
S00-S09 Injuries to the head	0.916	0.084
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.916	0.084
S40-S49 Injuries to the shoulder and upper arm	0.913	0.087
F00-F09 Organic, including symptomatic, mental disorders	0.912	0.088
Chapter XX External causes of morbidity and mortality	0.909	0.091
F99-F99 Unspecified mental disorder	0.906	0.094
G90-G99 Other disorders of the nervous system	0.903	0.097
J40-J47 Chronic lower respiratory diseases	0.902	0.098
E00-E07 Disorders of thyroid gland	0.900	0.100
T43.2 Other and unspecified antidepressants	0.897	0.103
N13 Obstructive and reflux uropathy	0.894	0.106
M20-M25 Other joint disorders	0.892	0.108
G50-G59 Nerve, nerve root and plexus disorders	0.888	0.112
T93 Sequelae of injuries of lower limb	0.884	0.116
N28 Other disorders of kidney and ureter, not elsewhere classified	0.882	0.118
H35 Other retinal disorders	0.881	0.119
M79 Other soft tissue disorders, not elsewhere classified	0.879	0.121
J18 Pneumonia, organism unspecified	0.878	0.122
M65 Synovitis and tenosynovitis	0.871	0.129
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.869	0.131
Chapter II Neoplasms	0.869	0.131
S83.2 Tear of meniscus, current	0.867	0.133
E66.9 Obesity, unspecified	0.864	0.136
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.864	0.136
Chapter I Certain infectious and parasitic diseases	0.862	0.138
E10-E14 Diabetes mellitus	0.861	0.139
T39.0 Salicylates	0.858	0.142
S60-S69 Injuries to the wrist and hand	0.858	0.142
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.858	0.142
S70-S79 Injuries to the hip and thigh	0.858	0.142
T51 Toxic effect of alcohol	0.856	0.144
J18.9 Pneumonia, unspecified	0.855	0.145
N18.9 Chronic renal failure, unspecified	0.853	0.147
S02 Fracture of skull and facial bones	0.853	0.147
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.853	0.147
S90-S99 Injuries to the ankle and foot	0.850	0.150
M06 Other rheumatoid arthritis	0.846	0.154
D37-D48 Neoplasms of uncertain or unknown behaviour	0.845	0.155
M75 Shoulder lesions	0.845	0.155
H40.2 Primary angle-closure glaucoma	0.845	0.155
F40-F48 Neurotic, stress-related and somatoform disorders	0.844	0.156
F99 Mental disorder, not otherwise specified	0.841	0.159
F31 Bipolar affective disorder	0.840	0.160
H53-H54 Visual disturbances and blindness	0.838	0.162
N13.3 Other and unspecified hydronephrosis	0.837	0.163
N28.8 Other specified disorders of kidney and ureter	0.834	0.166
N18.4 Chronic kidney disease, stage 4	0.827	0.173
H35.3 Degeneration of macula and posterior pole	0.825	0.175
V20-V29 Motorcycle rider injured in transport accident	0.825	0.175
S81 Open wound of lower leg	0.824	0.176
G93 Other disorders of brain	0.824	0.176
H46-H48 Disorders of optic nerve and visual pathways	0.824	0.176
M79.8 Other specified soft tissue disorders	0.823	0.177
S82.3 Fracture of lower end of tibia	0.822	0.178
J47 Bronchiectasis	0.819	0.181
S32 Fracture of lumbar spine and pelvis	0.816	0.184
G80-G83 Cerebral palsy and other paralytic syndromes	0.812	0.188
F32 Depressive episode	0.809	0.191
N20-N23 Urolithiasis	0.809	0.191
M75.1 Rotator cuff syndrome	0.806	0.194
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.805	0.195
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.805	0.195
M65.9 Synovitis and tenosynovitis, unspecified	0.804	0.196
S42 Fracture of shoulder and upper arm	0.802	0.198
F05 Delirium, not induced by alcohol and other psychoactive substances	0.800	0.200
E10 Insulin-dependent diabetes mellitus	0.799	0.201
N18.2 Chronic kidney disease, stage 2	0.797	0.203
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.796	0.204
C51-C58 Malignant neoplasms of female genital organs	0.796	0.204
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.795	0.204
S82.2 Fracture of shaft of tibia	0.795	0.205
H40.9 Glaucoma, unspecified	0.792	0.208
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.792	0.208
H40.0 Glaucoma suspect	0.792	0.208
F80-F89 Disorders of psychological development	0.791	0.209
Chapter XV Pregnancy, childbirth and the puerperium	0.789	0.211
M06.9 Rheumatoid arthritis, unspecified	0.788	0.212
G35-G37 Demyelinating diseases of the central nervous system	0.786	0.214
T51.0 Ethanol	0.785	0.215
T90 Sequelae of injuries of head	0.785	0.215
E03 Other hypothyroidism	0.785	0.215
T15-T19 Effects of foreign body entering through natural orifice	0.783	0.217
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.782	0.218
A30-A49 Other bacterial diseases	0.779	0.221
S20-S29 Injuries to the thorax	0.778	0.222
J44 Other chronic obstructive pulmonary disease	0.778	0.222
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.777	0.223
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.776	0.224
N18.8 Other chronic renal failure	0.776	0.224
T40.2 Other opioids	0.776	0.224
G30-G32 Other degenerative diseases of the nervous system	0.776	0.224
Chapter XXII Codes for special purposes	0.775	0.225
M24 Other specific joint derangements	0.775	0.225
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.775	0.225
D00-D09 In situ neoplasms	0.774	0.226
S02.2 Fracture of nasal bones	0.773	0.227
M86-M90 Other osteopathies	0.772	0.228
B35-B49 Mycoses	0.772	0.228
F41 Other anxiety disorders	0.770	0.230
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.769	0.230
S00 Superficial injury of head	0.768	0.232
N18.0 End-stage renal disease	0.766	0.234
S82.4 Fracture of fibula alone	0.765	0.235
T93.0 Sequelae of open wound of lower limb	0.764	0.236
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.764	0.236
H10-H13 Disorders of conjunctiva	0.764	0.236
M25 Other joint disorders, not elsewhere classified	0.764	0.236
J00-J06 Acute upper respiratory infections	0.762	0.238
E20-E35 Disorders of other endocrine glands	0.761	0.239
T43.0 Tricyclic and tetracyclic antidepressants	0.761	0.239
M21 Other acquired deformities of limbs	0.760	0.240
M91-M94 Chondropathies	0.759	0.240
E50-E64 Other nutritional deficiencies	0.759	0.241
M00-M03 Infectious arthropathies	0.758	0.242
S80 Superficial injury of lower leg	0.758	0.242
H43-H45 Disorders of vitreous body and globe	0.757	0.243
E05 Thyrotoxicosis [hyperthyroidism]	0.757	0.243
J11 Influenza, virus not identified	0.757	0.243
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.757	0.243
D45 Polycythaemia vera	0.755	0.245
G62 Other polyneuropathies	0.754	0.246
J90-J94 Other diseases of pleura	0.754	0.246
M07 Psoriatic and enteropathic arthropathies	0.754	0.246
H55-H59 Other disorders of eye and adnexa	0.753	0.247
M50-M54 Other dorsopathies	0.751	0.249
N00-N08 Glomerular diseases	0.750	0.250
G93.8 Other specified disorders of brain	0.750	0.250
T50.9 Other and unspecified drugs, medicaments and biological substances	0.748	0.252
H36 Retinal disorders in diseases classified elsewhere	0.746	0.254
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.741	0.259
S82.6 Fracture of lateral malleolus	0.741	0.259
S82.30 Fracture of lower end of tibia (closed)	0.740	0.260
S62 Fracture at wrist and hand level	0.738	0.262
G51 Facial nerve disorders	0.737	0.263
M67 Other disorders of synovium and tendon	0.736	0.264
N28.1 Cyst of kidney, acquired	0.735	0.265
H33 Retinal detachments and breaks	0.734	0.266
M31 Other necrotising vasculopathies	0.732	0.268
M05 Seropositive rheumatoid arthritis	0.729	0.271
G70-G73 Diseases of myoneural junction and muscle	0.729	0.271
Chapter XXI Factors influencing health status and contact with health services	0.729	0.271
J43 Emphysema	0.728	0.272
G56 Mononeuropathies of upper limb	0.728	0.272
F60-F69 Disorders of adult personality and behaviour	0.726	0.274
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.726	0.274
S40 Superficial injury of shoulder and upper arm	0.725	0.275
T92 Sequelae of injuries of upper limb	0.724	0.276
N11 Chronic tubulo-interstitial nephritis	0.723	0.276
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.723	0.277
S92 Fracture of foot, except ankle	0.722	0.278
T66-T78 Other and unspecified effects of external causes	0.721	0.279
G50 Disorders of trigeminal nerve	0.721	0.279
V23.4 Driver injured in traffic accident	0.721	0.279
F05.9 Delirium, unspecified	0.720	0.280
F31.9 Bipolar affective disorder, unspecified	0.719	0.281
F00 Dementia in Alzheimer's disease	0.718	0.281
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
S02.20 Fracture of nasal bones (closed)	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.716	0.284
T46 Poisoning by agents primarily affecting the cardiovascular system	0.716	0.284
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.716	0.284
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
T36 Poisoning by systemic antibiotics	0.716	0.284
M60-M63 Disorders of muscles	0.715	0.285
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.715	0.285
W00-W19 Falls	0.715	0.285
E40-E46 Malnutrition	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
M80-M85 Disorders of bone density and structure	0.713	0.287
S88 Traumatic amputation of lower leg	0.713	0.287
S87 Crushing injury of lower leg	0.713	0.287
S86 Injury of muscle and tendon at lower leg level	0.713	0.287
S85 Injury of blood vessels at lower leg level	0.713	0.287
S84 Injury of nerves at lower leg level	0.713	0.287
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.712	0.288
G95 Other diseases of spinal cord	0.712	0.288
E04 Other non-toxic goitre	0.711	0.289
T79-T79 Certain early complications of trauma	0.710	0.290
T51.9 Alcohol, unspecified	0.710	0.290
G99 Other disorders of nervous system in diseases classified elsewhere	0.710	0.290
N13.8 Other obstructive and reflux uropathy	0.708	0.292
T93.9 Sequelae of unspecified injury of lower limb	0.708	0.292
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.707	0.293
G00-G09 Inflammatory diseases of the central nervous system	0.707	0.293
E10.3 With ophthalmic complications	0.707	0.293
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.706	0.294
M79.86 Other specified soft tissue disorders (Lower leg)	0.706	0.294
J80-J84 Other respiratory diseases principally affecting the interstitium	0.706	0.294
J95-J99 Other diseases of the respiratory system	0.705	0.295
T43.3 Phenothiazine antipsychotics and neuroleptics	0.705	0.295
J44.9 Chronic obstructive pulmonary disease, unspecified	0.704	0.296
S89 Other and unspecified injuries of lower leg	0.703	0.297
E03.9 Hypothyroidism, unspecified	0.703	0.297
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.701	0.299
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.701	0.299
T39.4 Antirheumatics, not elsewhere classified	0.701	0.299
T39.2 Pyrazolone derivatives	0.701	0.299
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.700	0.299
E67 Other hyperalimentation	0.700	0.300
E68 Sequelae of hyperalimentation	0.700	0.300
E65 Localised adiposity	0.700	0.300
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.700	0.300
S82.5 Fracture of medial malleolus	0.697	0.303
S32.5 Fracture of pubis	0.697	0.303
M10 Gout	0.697	0.303
B35 Dermatophytosis	0.695	0.305
J10 Influenza due to identified influenza virus	0.695	0.305
J46 Status asthmaticus	0.695	0.305
O94-O99 Other obstetric conditions, not elsewhere classified	0.695	0.305
G62.9 Polyneuropathy, unspecified	0.694	0.306
M79.80 Other specified soft tissue disorders (Multiple sites)	0.694	0.306
G59 Mononeuropathy in diseases classified elsewhere	0.693	0.307
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.693	0.307
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.693	0.307
S46 Injury of muscle and tendon at shoulder and upper arm level	0.692	0.307
N13.5 Kinking and stricture of ureter without hydronephrosis	0.692	0.308
C54 Malignant neoplasm of corpus uteri	0.691	0.309
E66.2 Extreme obesity with alveolar hypoventilation	0.691	0.309
E66.1 Drug-induced obesity	0.691	0.309
E66.0 Obesity due to excess calories	0.691	0.309
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.691	0.309
H40.5 Glaucoma secondary to other eye disorders	0.690	0.310
F32.2 Severe depressive episode without psychotic symptoms	0.690	0.310
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.689	0.311
H54 Blindness and low vision	0.688	0.312
M25.7 Osteophyte	0.687	0.313
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.686	0.313
H42 Glaucoma in diseases classified elsewhere	0.685	0.315
S71 Open wound of hip and thigh	0.685	0.315
H47 Other disorders of optic [2nd] nerve and visual pathways	0.684	0.316
N18.1 Chronic kidney disease, stage 1	0.684	0.316
S83.7 Injury to multiple structures of knee	0.684	0.316
S83.6 Sprain and strain of other and unspecified parts of knee	0.684	0.316
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.684	0.316
S83.3 Tear of articular cartilage of knee, current	0.684	0.316
S83.1 Dislocation of knee	0.684	0.316
S83.0 Dislocation of patella	0.684	0.316
S82.1 Fracture of upper end of tibia	0.683	0.317
S06 Intracranial injury	0.683	0.317
T98 Sequelae of other and unspecified effects of external causes	0.682	0.318
T95 Sequelae of burns, corrosions and frostbite	0.682	0.318
T94 Sequelae of injuries involving multiple and unspecified body regions	0.682	0.318
T91 Sequelae of injuries of neck and trunk	0.682	0.318
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.682	0.318
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.682	0.318
H35.7 Separation of retinal layers	0.682	0.318
T43.9 Psychotropic drug, unspecified	0.681	0.318
T43.8 Other psychotropic drugs, not elsewhere classified	0.681	0.318
T43.6 Psychostimulants with abuse potential	0.681	0.318
T43.5 Other and unspecified antipsychotics and neuroleptics	0.681	0.318
T43.4 Butyrophenone and thioxanthene neuroleptics	0.681	0.318
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.681	0.318
M76 Enthesopathies of lower limb, excluding foot	0.681	0.319
M73 Soft tissue disorders in diseases classified elsewhere	0.681	0.319
M71 Other bursopathies	0.681	0.319
M65.4 Radial styloid tenosynovitis [de Quervain]	0.681	0.319
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.680	0.319
D47.1 Chronic myeloproliferative disease	0.679	0.321
S50-S59 Injuries to the elbow and forearm	0.679	0.321
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.679	0.321
H35.4 Peripheral retinal degeneration	0.678	0.322
F41.2 Mixed anxiety and depressive disorder	0.678	0.322
M77 Other enthesopathies	0.678	0.322
F01 Vascular dementia	0.676	0.324
H32 Chorioretinal disorders in diseases classified elsewhere	0.675	0.325
H31 Other disorders of choroid	0.675	0.325
H30 Chorioretinal inflammation	0.675	0.325
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.675	0.325
H40.1 Primary open-angle glaucoma	0.674	0.325
S66 Injury of muscle and tendon at wrist and hand level	0.674	0.326
S70 Superficial injury of hip and thigh	0.674	0.326
S02.4 Fracture of malar and maxillary bones	0.674	0.326
A49 Bacterial infection of unspecified site	0.673	0.327
G63 Polyneuropathy in diseases classified elsewhere	0.672	0.328
S82.9 Fracture of lower leg, part unspecified	0.672	0.328
S82.7 Multiple fractures of lower leg	0.672	0.328
N20 Calculus of kidney and ureter	0.671	0.329
M79.0 Rheumatism, unspecified	0.671	0.329
F33 Recurrent depressive disorder	0.670	0.330
N17 Acute renal failure	0.670	0.330
S32.0 Fracture of lumbar vertebra	0.670	0.330
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.670	0.330
N15 Other renal tubulo-interstitial diseases	0.670	0.330
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.670	0.330
F38 Other mood [affective] disorders	0.669	0.330
F34 Persistent mood [affective] disorders	0.669	0.330
F30 Manic episode	0.669	0.330
F39 Unspecified mood [affective] disorder	0.669	0.330
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.669	0.331
M66 Spontaneous rupture of synovium and tendon	0.669	0.331
X60-X84 Intentional self-harm	0.669	0.331
M72 Fibroblastic disorders	0.669	0.331
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.668	0.332
J18.1 Lobar pneumonia, unspecified	0.667	0.333
E10.4 With neurological complications	0.667	0.333
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.667	0.333
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.666	0.333
N27 Small kidney of unknown cause	0.666	0.333
N25 Disorders resulting from impaired renal tubular function	0.666	0.333
N26 Unspecified contracted kidney	0.666	0.333
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.666	0.334
E05.9 Thyrotoxicosis, unspecified	0.666	0.334
H40.8 Other glaucoma	0.666	0.334
H40.6 Glaucoma secondary to drugs	0.666	0.334
H40.4 Glaucoma secondary to eye inflammation	0.666	0.334
H40.3 Glaucoma secondary to eye trauma	0.666	0.334
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.665	0.335
S37 Injury of urinary and pelvic organs	0.665	0.335
S36 Injury of intra-abdominal organs	0.665	0.335
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.665	0.335
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.665	0.335
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.665	0.335
S31 Open wound of abdomen, lower back and pelvis	0.665	0.335
S30 Superficial injury of abdomen, lower back and pelvis	0.665	0.335
G93.2 Benign intracranial hypertension	0.665	0.335
M14 Arthropathies in other diseases classified elsewhere	0.664	0.336
M12 Other specific arthropathies	0.664	0.336
M09 Juvenile arthritis in diseases classified elsewhere	0.664	0.336
M08 Juvenile arthritis	0.664	0.336
F03 Unspecified dementia	0.663	0.336
S82.20 Fracture of shaft of tibia (closed)	0.663	0.337
S02.1 Fracture of base of skull	0.662	0.338
M75.2 Bicipital tendinitis	0.661	0.339
N99-N99 Other disorders of the genitourinary system	0.661	0.339
J17 Pneumonia in diseases classified elsewhere	0.661	0.339
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.661	0.339
J15 Bacterial pneumonia, not elsewhere classified	0.661	0.339
J12 Viral pneumonia, not elsewhere classified	0.661	0.339
J14 Pneumonia due to Haemophilus influenzae	0.661	0.339
J09 Influenza due to certain identified influenza virus	0.661	0.339
Y44 Agents primarily affecting blood constituents	0.661	0.339
B15-B19 Viral hepatitis	0.661	0.339
G93.4 Encephalopathy, unspecified	0.661	0.339
H53 Visual disturbances	0.660	0.340
S60 Superficial injury of wrist and hand	0.659	0.341
E10.5 With peripheral circulatory complications	0.659	0.341
M11 Other crystal arthropathies	0.658	0.341
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.658	0.342
Z91 Personal history of risk-factors, not elsewhere classified	0.658	0.342
M65.3 Trigger finger	0.658	0.342
G96 Other disorders of central nervous system	0.657	0.343
S08 Traumatic amputation of part of head	0.657	0.343
S07 Crushing injury of head	0.657	0.343
S05 Injury of eye and orbit	0.657	0.343
S04 Injury of cranial nerves	0.657	0.343
S03 Dislocation, sprain and strain of joints and ligaments of head	0.657	0.343
T65 Toxic effect of other and unspecified substances	0.657	0.343
T63 Toxic effect of contact with venomous animals	0.657	0.343
T62 Toxic effect of other noxious substances eaten as food	0.657	0.343
T61 Toxic effect of noxious substances eaten as seafood	0.657	0.343
T60 Toxic effect of pesticides	0.657	0.343
T59 Toxic effect of other gases, fumes and vapours	0.657	0.343
T57 Toxic effect of other inorganic substances	0.657	0.343
T56 Toxic effect of metals	0.657	0.343
T54 Toxic effect of corrosive substances	0.657	0.343
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.657	0.343
T52 Toxic effect of organic solvents	0.657	0.343
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.657	0.343
T58 Toxic effect of carbon monoxide	0.657	0.343
T55 Toxic effect of soaps and detergents	0.657	0.343
X40-X49 Accidental poisoning by and exposure to noxious substances	0.656	0.344
G58 Other mononeuropathies	0.655	0.345
S49 Other and unspecified injuries of shoulder and upper arm	0.655	0.345
S48 Traumatic amputation of shoulder and upper arm	0.655	0.345
S45 Injury of blood vessels at shoulder and upper arm level	0.655	0.345
S44 Injury of nerves at shoulder and upper arm level	0.655	0.345
S41 Open wound of shoulder and upper arm	0.655	0.345
S47 Crushing injury of shoulder and upper arm	0.655	0.345
J60-J70 Lung diseases due to external agents	0.654	0.346
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.654	0.346
F02 Dementia in other diseases classified elsewhere	0.654	0.346
F09 Unspecified organic or symptomatic mental disorder	0.654	0.346
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.654	0.346
M31.3 Wegener's granulomatosis	0.654	0.346
H34 Retinal vascular occlusions	0.653	0.347
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.652	0.348
Y35-Y36 Legal intervention and operations of war	0.652	0.348
Y10-Y34 Event of undetermined intent	0.652	0.348
Y00-Y09 Assault	0.652	0.348
X85-X99 Assault	0.652	0.348
X58-X59 Accidental exposure to other and unspecified factors	0.652	0.348
X50-X57 Overexertion, travel and privation	0.652	0.348
X30-X39 Exposure to forces of nature	0.652	0.348
X20-X29 Contact with venomous animals and plants	0.652	0.348
X10-X19 Contact with heat and hot substances	0.652	0.348
X00-X09 Exposure to smoke, fire and flames	0.652	0.348
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.652	0.348
W75-W84 Other accidental threats to breathing	0.652	0.348
W65-W74 Accidental drowning and submersion	0.652	0.348
W50-W64 Exposure to animate mechanical forces	0.652	0.348
V98-V99 Other and unspecified transport accidents	0.652	0.348
V95-V97 Air and space transport accidents	0.652	0.348
V90-V94 Water transport accidents	0.652	0.348
V80-V89 Other land transport accidents	0.652	0.348
V70-V79 Bus occupant injured in transport accident	0.652	0.348
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.652	0.348
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.652	0.348
V40-V49 Car occupant injured in transport accident	0.652	0.348
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.652	0.348
V01-V09 Pedestrian injured in transport accident	0.652	0.348
F32.9 Depressive episode, unspecified	0.652	0.348
S42.9 Fracture of shoulder girdle, part unspecified	0.652	0.348
M79.5 Residual foreign body in soft tissue	0.651	0.349
S42.2 Fracture of upper end of humerus	0.650	0.350
T42.4 Benzodiazepines	0.649	0.351
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.649	0.351
M35 Other systemic involvement of connective tissue	0.648	0.352
S90 Superficial injury of ankle and foot	0.648	0.352
S81.0 Open wound of knee	0.648	0.352
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.647	0.352
G94 Other disorders of brain in diseases classified elsewhere	0.647	0.352
G90 Disorders of autonomic nervous system	0.647	0.352
G98 Other disorders of nervous system, not elsewhere classified	0.647	0.352
G92 Toxic encephalopathy	0.647	0.352
J41 Simple and mucopurulent chronic bronchitis	0.647	0.353
N13.4 Hydroureter	0.647	0.353
S72 Fracture of femur	0.647	0.353
H35.0 Background retinopathy and retinal vascular changes	0.646	0.353
A80-A89 Viral infections of the central nervous system	0.646	0.354
D03 Melanoma in situ	0.646	0.354
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.645	0.355
E00 Congenital iodine-deficiency syndrome	0.645	0.355
E02 Subclinical iodine-deficiency hypothyroidism	0.645	0.355
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.645	0.355
F81 Specific developmental disorders of scholastic skills	0.645	0.355
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.644	0.356
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.644	0.356
A50-A64 Infections with a predominantly sexual mode of transmission	0.644	0.356
H50 Other strabismus	0.643	0.357
M75.3 Calcific tendinitis of shoulder	0.643	0.357
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.642	0.358
M70 Soft tissue disorders related to use, overuse and pressure	0.642	0.358
J92 Pleural plaque	0.642	0.358
T18 Foreign body in alimentary tract	0.642	0.358
S82.40 Fracture of fibula alone (closed)	0.641	0.359
N13.9 Obstructive and reflux uropathy, unspecified	0.641	0.359
N13.7 Vesicoureteral-reflux-associated uropathy	0.641	0.359
N13.6 Pyonephrosis	0.641	0.359
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.641	0.359
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.640	0.360
M34 Systemic sclerosis	0.640	0.360
M33 Dermatopolymyositis	0.640	0.360
M32 Systemic lupus erythematosus	0.640	0.360
M30 Polyarteritis nodosa and related conditions	0.640	0.360
D09 Carcinoma in situ of other and unspecified sites	0.640	0.360
E06 Thyroiditis	0.640	0.360
S79 Other and unspecified injuries of hip and thigh	0.640	0.360
W20-W49 Exposure to inanimate mechanical forces	0.640	0.360
M45-M49 Spondylopathies	0.639	0.361
H49 Paralytic strabismus	0.639	0.361
J11.1 Influenza with other respiratory manifestations, virus not identified	0.639	0.361
S42.1 Fracture of scapula	0.638	0.362
G80 Infantile cerebral palsy	0.637	0.363
G54 Nerve root and plexus disorders	0.637	0.363

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations