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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117693426
log Bayes Factor = 13.2487
Chromosome 14   position 105,884,482  (GRCh37) Explore rs117693426 on Ensembl!
Variant rs117693426 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
C50-C50 Malignant neoplasm of breast
0.997 0.003 0.000
M06 Other rheumatoid arthritis
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
C50 Malignant neoplasm of breast
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.993 0.007 0.000
C50.9 Breast, unspecified
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
S00-S09 Injuries to the head
0.980 0.020 0.000
M70-M79 Other soft tissue disorders
0.978 0.022 0.000
H36 Retinal disorders in diseases classified elsewhere
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.973 0.027 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.973 0.027 0.000
H35 Other retinal disorders
0.968 0.032 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.965 0.035 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.963 0.037 0.000
H36.0 Diabetic retinopathy
0.960 0.040 0.000
I35 Nonrheumatic aortic valve disorders
0.956 0.044 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.956 0.044 0.000
S01 Open wound of head
0.955 0.045 0.000
C50.4 Upper-outer quadrant of breast
0.945 0.055 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.940 0.060 0.000
I73 Other peripheral vascular diseases
0.939 0.061 0.000
H35.8 Other specified retinal disorders
0.931 0.069 0.000
Chapter I Certain infectious and parasitic diseases
0.929 0.071 0.000
M05 Seropositive rheumatoid arthritis
0.920 0.080 0.000
W00-W19 Falls
0.908 0.092 0.000
Y43 Primarily systemic agents
0.908 0.092 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.907 0.093 0.000
I73.9 Peripheral vascular disease, unspecified
0.903 0.097 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.902 0.098 0.000
I34 Nonrheumatic mitral valve disorders
0.899 0.101 0.000
D00-D09 In situ neoplasms
0.894 0.106 0.000
Chapter XXII Codes for special purposes
0.893 0.107 0.000
I35.0 Aortic (valve) stenosis
0.891 0.109 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.889 0.111 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.889 0.111 0.000
H34 Retinal vascular occlusions
0.888 0.112 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.888 0.112 0.000
M79.6 Pain in limb
0.888 0.112 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.887 0.113 0.000
M20-M25 Other joint disorders
0.885 0.115 0.000
B95-B98 Bacterial, viral and other infectious agents
0.874 0.126 0.000
I42 Cardiomyopathy
0.874 0.126 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.872 0.128 0.000
I60-I69 Cerebrovascular diseases
0.872 0.128 0.000
M80-M85 Disorders of bone density and structure
0.871 0.129 0.000
H33 Retinal detachments and breaks
0.868 0.132 0.000
C51-C58 Malignant neoplasms of female genital organs
0.867 0.133 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.864 0.136 0.000
S01.9 Open wound of head, part unspecified
0.857 0.143 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.855 0.145 0.000
H35.0 Background retinopathy and retinal vascular changes
0.850 0.150 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.846 0.154 0.000
S01.8 Open wound of other parts of head
0.845 0.155 0.000
D05 Carcinoma in situ of breast
0.842 0.158 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.842 0.158 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.840 0.160 0.000
H10-H13 Disorders of conjunctiva
0.838 0.162 0.000
T66-T78 Other and unspecified effects of external causes
0.837 0.163 0.000
Y43.3 Other antineoplastic drugs
0.835 0.165 0.000
S05 Injury of eye and orbit
0.834 0.166 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.832 0.168 0.000
L50-L54 Urticaria and erythema
0.831 0.169 0.000
G30-G32 Other degenerative diseases of the nervous system
0.830 0.170 0.000
M45-M49 Spondylopathies
0.829 0.171 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.826 0.174 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.826 0.174 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.826 0.174 0.000
L82 Seborrhoeic keratosis
0.823 0.177 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.823 0.177 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.820 0.180 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.820 0.180 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.818 0.181 0.000
L90 Atrophic disorders of skin
0.818 0.182 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.817 0.183 0.000
S40-S49 Injuries to the shoulder and upper arm
0.817 0.183 0.000
I51 Complications and ill-defined descriptions of heart disease
0.815 0.185 0.000
I72 Other aneurysm
0.811 0.188 0.000
G40-G47 Episodic and paroxysmal disorders
0.811 0.189 0.000
M25 Other joint disorders, not elsewhere classified
0.810 0.190 0.000
S60-S69 Injuries to the wrist and hand
0.810 0.190 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.810 0.190 0.000
M65-M68 Disorders of synovium and tendon
0.806 0.194 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.805 0.195 0.000
I73.0 Raynaud's syndrome
0.805 0.195 0.000
M22 Disorders of patella
0.803 0.197 0.000
R47-R49 Symptoms and signs involving speech and voice
0.802 0.198 0.000
C50.5 Lower-outer quadrant of breast
0.801 0.199 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.799 0.201 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.799 0.201 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.795 0.205 0.000
C50.8 Overlapping lesion of breast
0.795 0.205 0.000
T00-T07 Injuries involving multiple body regions
0.794 0.206 0.000
L90.5 Scar conditions and fibrosis of skin
0.792 0.208 0.000
I05-I09 Chronic rheumatic heart diseases
0.792 0.208 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.791 0.209 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.791 0.209 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.791 0.209 0.000
Y57 Other and unspecified drugs and medicaments
0.790 0.210 0.000
C50.0 Nipple and areola
0.789 0.211 0.000
G90-G99 Other disorders of the nervous system
0.789 0.211 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.787 0.213 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.787 0.213 0.000
Y86 Sequelae of other accidents
0.787 0.213 0.000
M79.7 Fibromyalgia
0.786 0.214 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.786 0.214 0.000
T93 Sequelae of injuries of lower limb
0.785 0.214 0.000
M47 Spondylosis
0.785 0.215 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.783 0.217 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
I34.0 Mitral (valve) insufficiency
0.782 0.218 0.000
W18 Other fall on same level
0.782 0.218 0.000
S01.7 Multiple open wounds of head
0.782 0.218 0.000
A30-A49 Other bacterial diseases
0.781 0.219 0.000
S02 Fracture of skull and facial bones
0.780 0.220 0.000
I35.1 Aortic (valve) insufficiency
0.775 0.225 0.000
M79.1 Myalgia
0.774 0.226 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.774 0.226 0.000
S10-S19 Injuries to the neck
0.774 0.226 0.000
M79.60 Pain in limb (Multiple sites)
0.773 0.227 0.000
H33.2 Serous retinal detachment
0.773 0.227 0.000
M77 Other enthesopathies
0.772 0.228 0.000
I34.1 Mitral (valve) prolapse
0.772 0.228 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.772 0.228 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.771 0.229 0.000
I78 Diseases of capillaries
0.771 0.229 0.000
V40-V49 Car occupant injured in transport accident
0.770 0.230 0.000
H33.5 Other retinal detachments
0.770 0.230 0.000
M06.0 Seronegative rheumatoid arthritis
0.768 0.232 0.000
S06 Intracranial injury
0.767 0.233 0.000
R47 Speech disturbances, not elsewhere classified
0.766 0.234 0.000
G40 Epilepsy
0.764 0.236 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.764 0.236 0.000
S01.5 Open wound of lip and oral cavity
0.763 0.237 0.000
U80 Agent resistant to penicillin and related antibiotics
0.763 0.237 0.000
M71 Other bursopathies
0.763 0.237 0.000
V80-V89 Other land transport accidents
0.762 0.238 0.000
Q60-Q64 Congenital malformations of the urinary system
0.761 0.239 0.000
Y00-Y09 Assault
0.760 0.240 0.000
H35.6 Retinal haemorrhage
0.759 0.241 0.000
H31 Other disorders of choroid
0.759 0.241 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.759 0.241 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.758 0.242 0.000
R50-R69 General symptoms and signs
0.758 0.242 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.757 0.242 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.757 0.243 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.756 0.244 0.000
M13 Other arthritis
0.755 0.245 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
V10-V19 Pedal cyclist injured in transport accident
0.755 0.245 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.755 0.245 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.754 0.245 0.000
C71 Malignant neoplasm of brain
0.752 0.248 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.752 0.248 0.000
T39.1 4-Aminophenol derivatives
0.752 0.248 0.000
H34.8 Other retinal vascular occlusions
0.751 0.249 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.750 0.249 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
M11 Other crystal arthropathies
0.748 0.251 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.746 0.253 0.000
R53 Malaise and fatigue
0.746 0.254 0.000
M75 Shoulder lesions
0.746 0.254 0.000
H34.2 Other retinal artery occlusions
0.745 0.255 0.000
R51 Headache
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
I51.7 Cardiomegaly
0.743 0.257 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
Y43.1 Antineoplastic antimetabolites
0.742 0.258 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.742 0.258 0.000
C77.3 Axillary and upper limb lymph nodes
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.739 0.261 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.739 0.261 0.000
I35.8 Other aortic valve disorders
0.739 0.261 0.000
I67 Other cerebrovascular diseases
0.739 0.261 0.000
M76 Enthesopathies of lower limb, excluding foot
0.739 0.261 0.000
W07 Fall involving chair
0.739 0.261 0.000
S50-S59 Injuries to the elbow and forearm
0.738 0.262 0.000
Y44 Agents primarily affecting blood constituents
0.738 0.262 0.000
S01.2 Open wound of nose
0.736 0.264 0.000
S01.4 Open wound of cheek and temporomandibular area
0.736 0.264 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.735 0.265 0.000
M81 Osteoporosis without pathological fracture
0.734 0.266 0.000
I37 Pulmonary valve disorders
0.734 0.266 0.000
H43-H45 Disorders of vitreous body and globe
0.733 0.267 0.000
L85 Other epidermal thickening
0.733 0.267 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.733 0.267 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.732 0.268 0.000
M47.9 Spondylosis, unspecified
0.732 0.268 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
I30 Acute pericarditis
0.730 0.270 0.000
M72 Fibroblastic disorders
0.730 0.270 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.729 0.271 0.000
G62 Other polyneuropathies
0.728 0.271 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.726 0.274 0.000
I31 Other diseases of pericardium
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.723 0.277 0.000
M79.2 Neuralgia and neuritis, unspecified
0.721 0.279 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.721 0.279 0.000
T78 Adverse effects, not elsewhere classified
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.720 0.280 0.000
C54 Malignant neoplasm of corpus uteri
0.720 0.280 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.719 0.281 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.718 0.282 0.000
M22.4 Chondromalacia patellae
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C44 Other malignant neoplasms of skin
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
G20-G26 Extrapyramidal and movement disorders
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.285 0.000
H30 Chorioretinal inflammation
0.715 0.285 0.000
R47.0 Dysphasia and aphasia
0.714 0.286 0.000
T90 Sequelae of injuries of head
0.714 0.286 0.000
M06.8 Other specified rheumatoid arthritis
0.714 0.286 0.000
M06.4 Inflammatory polyarthropathy
0.714 0.286 0.000
M06.3 Rheumatoid nodule
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
L53 Other erythematous conditions
0.714 0.286 0.000
C50.6 Axillary tail of breast
0.713 0.286 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.713 0.287 0.000
C64-C68 Malignant neoplasms of urinary tract
0.713 0.287 0.000
M79.63 Pain in limb (Forearm)
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.712 0.288 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.712 0.288 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.711 0.289 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.709 0.290 0.000
M84 Disorders of continuity of bone
0.709 0.291 0.000
B35-B49 Mycoses
0.708 0.292 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.708 0.292 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
I99 Other and unspecified disorders of circulatory system
0.706 0.294 0.000
D45 Polycythaemia vera
0.706 0.294 0.000
I60 Subarachnoid haemorrhage
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.704 0.296 0.000
M34 Systemic sclerosis
0.704 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.297 0.000
I48 Atrial fibrillation and flutter
0.703 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.297 0.000
I40 Acute myocarditis
0.703 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.703 0.297 0.000
S07 Crushing injury of head
0.703 0.297 0.000
S04 Injury of cranial nerves
0.703 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.297 0.000
C53 Malignant neoplasm of cervix uteri
0.702 0.298 0.000
M79.0 Rheumatism, unspecified
0.702 0.298 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.702 0.298 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.701 0.299 0.000
I46 Cardiac arrest
0.701 0.299 0.000
L20-L30 Dermatitis and eczema
0.701 0.299 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.701 0.299 0.000
M79.64 Pain in limb (Hand)
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.699 0.301 0.000
M25.5 Pain in joint
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
I42.0 Dilated cardiomyopathy
0.699 0.301 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.698 0.302 0.000
Y59 Other and unspecified vaccines and biological substances
0.698 0.302 0.000
Y58 Bacterial vaccines
0.698 0.302 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.698 0.302 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.698 0.302 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
Y48 Anaesthetics and therapeutic gases
0.698 0.302 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.698 0.302 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.698 0.302 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
I77 Other disorders of arteries and arterioles
0.697 0.303 0.000
I95 Hypotension
0.697 0.303 0.000
M67 Other disorders of synovium and tendon
0.696 0.304 0.000
W08 Fall involving other furniture
0.696 0.304 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.695 0.305 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.695 0.305 0.000
H35.9 Retinal disorder, unspecified
0.694 0.306 0.000
H35.7 Separation of retinal layers
0.694 0.306 0.000
H35.5 Hereditary retinal dystrophy
0.694 0.306 0.000
H35.2 Other proliferative retinopathy
0.694 0.306 0.000
H35.1 Retinopathy of prematurity
0.694 0.306 0.000
S62 Fracture at wrist and hand level
0.694 0.306 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.694 0.306 0.000
I35.9 Aortic valve disorder, unspecified
0.694 0.306 0.000
U80.1 Methicillin resistant agent
0.693 0.307 0.000
T92 Sequelae of injuries of upper limb
0.693 0.307 0.000
Y40 Systemic antibiotics
0.693 0.307 0.000
H35.4 Peripheral retinal degeneration
0.693 0.307 0.000
I42.2 Other hypertrophic cardiomyopathy
0.692 0.308 0.000
M24 Other specific joint derangements
0.692 0.308 0.000
R49 Voice disturbances
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
T36 Poisoning by systemic antibiotics
0.692 0.308 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.309 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.690 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.312 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.687 0.313 0.000
M79.69 Pain in limb (Site unspecified)
0.686 0.314 0.000
I49 Other cardiac arrhythmias
0.686 0.314 0.000
Y52 Agents primarily affecting the cardiovascular system
0.685 0.314 0.000
L10-L14 Bullous disorders
0.685 0.315 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.685 0.315 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
I72.0 Aneurysm of carotid artery
0.683 0.317 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
D46 Myelodysplastic syndromes
0.682 0.318 0.000
G40.9 Epilepsy, unspecified
0.682 0.318 0.000
R41.3 Other amnesia
0.680 0.320 0.000
H11 Other disorders of conjunctiva
0.680 0.320 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.679 0.321 0.000
S68 Traumatic amputation of wrist and hand
0.678 0.322 0.000
S05.9 Injury of eye and orbit, part unspecified
0.678 0.322 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.678 0.322 0.000
M79.62 Pain in limb (Upper arm)
0.676 0.323 0.000
C51 Malignant neoplasm of vulva
0.676 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.675 0.325 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.675 0.325 0.000
I08 Multiple valve diseases
0.675 0.325 0.000
S05.8 Other injuries of eye and orbit
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.674 0.326 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.674 0.326 0.000
M79.3 Panniculitis, unspecified
0.674 0.326 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.327 0.000
H33.1 Retinoschisis and retinal cysts
0.673 0.327 0.000
I73.8 Other specified peripheral vascular diseases
0.673 0.327 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
I38 Endocarditis, valve unspecified
0.670 0.330 0.000
S80-S89 Injuries to the knee and lower leg
0.670 0.330 0.000
H10 Conjunctivitis
0.668 0.332 0.000
C77.4 Inguinal and lower limb lymph nodes
0.668 0.332 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.667 0.333 0.000
G93 Other disorders of brain
0.667 0.333 0.000
M25.4 Effusion of joint
0.667 0.333 0.000
C50.1 Central portion of breast
0.666 0.334 0.000
B99-B99 Other infectious diseases
0.666 0.334 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.666 0.334 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.666 0.334 0.000
B65-B83 Helminthiases
0.666 0.334 0.000
B50-B64 Protozoal diseases
0.666 0.334 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.666 0.334 0.000
A75-A79 Rickettsioses
0.666 0.334 0.000
A70-A74 Other diseases caused by chlamydiae
0.666 0.334 0.000
A65-A69 Other spirochaetal diseases
0.666 0.334 0.000
A20-A28 Certain zoonotic bacterial diseases
0.666 0.334 0.000
A15-A19 Tuberculosis
0.666 0.334 0.000
T40.2 Other opioids
0.666 0.334 0.000
Y42.5 Other oestrogens and progestogens
0.666 0.334 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.665 0.335 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.664 0.336 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.663 0.336 0.000
W13 Fall from, out of or through building or structure
0.663 0.337 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.663 0.337 0.000
M25.8 Other specified joint disorders
0.663 0.337 0.000
M31 Other necrotising vasculopathies
0.661 0.339 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
Y54.3 Benzothiadiazine derivatives
0.660 0.340 0.000
A41 Other septicaemia
0.660 0.340 0.000
M05.8 Other seropositive rheumatoid arthritis
0.659 0.340 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.659 0.340 0.000
M05.2 Rheumatoid vasculitis
0.659 0.340 0.000
M05.1 Rheumatoid lung disease
0.659 0.340 0.000
M05.0 Felty's syndrome
0.659 0.340 0.000
Y57.9 Drug or medicament, unspecified
0.658 0.342 0.000
G82 Paraplegia and tetraplegia
0.658 0.342 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.342 0.000
M75.1 Rotator cuff syndrome
0.657 0.343 0.000
Q61 Cystic kidney disease
0.657 0.343 0.000
D06 Carcinoma in situ of cervix uteri
0.656 0.343 0.000
R40 Somnolence, stupor and coma
0.656 0.344 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.656 0.344 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.656 0.344 0.000
L93 Lupus erythematosus
0.655 0.345 0.000
S01.3 Open wound of ear
0.654 0.346 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.654 0.346 0.000
W06 Fall involving bed
0.653 0.347 0.000
B25-B34 Other viral diseases
0.653 0.347 0.000
L89 Decubitus ulcer
0.653 0.347 0.000
I67.8 Other specified cerebrovascular diseases
0.653 0.347 0.000
C77.0 Lymph nodes of head, face and neck
0.652 0.348 0.000
L50 Urticaria
0.652 0.348 0.000
S69 Other and unspecified injuries of wrist and hand
0.652 0.348 0.000
W17 Other fall from one level to another
0.651 0.349 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.651 0.349 0.000
W15 Fall from cliff
0.651 0.349 0.000
W14 Fall from tree
0.651 0.349 0.000
W12 Fall on and from scaffolding
0.651 0.349 0.000
W11 Fall on and from ladder
0.651 0.349 0.000
W09 Fall involving playground equipment
0.651 0.349 0.000
W05 Fall involving wheelchair
0.651 0.349 0.000
W04 Fall while being carried or supported by other persons
0.651 0.349 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.651 0.349 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.651 0.349 0.000
W00 Fall on same level involving ice and snow
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
Y43.9 Primarily systemic agent, unspecified
0.651 0.349 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.651 0.349 0.000
Y43.6 Enzymes, not elsewhere classified
0.651 0.349 0.000
Y43.5 Acidifying and alkalising agents
0.651 0.349 0.000
Y43.4 Immunosuppressive agents
0.651 0.349 0.000
Y43.2 Antineoplastic natural products
0.651 0.349 0.000
Y43.0 Antiallergic and antiemetic drugs
0.651 0.349 0.000
S01.0 Open wound of scalp
0.651 0.349 0.000
W18.3 Sports and athletics area
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.651 0.349 0.000
I33 Acute and subacute endocarditis
0.650 0.350 0.000
Chapter VIII Diseases of the ear and mastoid process
0.650 0.350 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.648 0.352 0.000
T01 Open wounds involving multiple body regions
0.647 0.353 0.000
T98 Sequelae of other and unspecified effects of external causes
0.647 0.353 0.000
T95 Sequelae of burns, corrosions and frostbite
0.647 0.353 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.647 0.353 0.000
T91 Sequelae of injuries of neck and trunk
0.647 0.353 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.647 0.353 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.647 0.353 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.646 0.354 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.645 0.355 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.645 0.355 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.645 0.355 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.645 0.355 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.644 0.356 0.000
M79.79 Fibromyalgia (Site unspecified)
0.644 0.356 0.000
M07 Psoriatic and enteropathic arthropathies
0.642 0.358 0.000
D05.0 Lobular carcinoma in situ
0.642 0.358 0.000
C09 Malignant neoplasm of tonsil
0.641 0.359 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.641 0.359 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.641 0.359 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.641 0.359 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.641 0.359 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.640 0.359 0.000
Q00-Q07 Congenital malformations of the nervous system
0.640 0.360 0.000
I47 Paroxysmal tachycardia
0.640 0.360 0.000
M22.8 Other disorders of patella
0.640 0.360 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.640 0.360 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.639 0.361 0.000
M79.10 Myalgia (Multiple sites)
0.639 0.361 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.638 0.362 0.000
L94 Other localised connective tissue disorders
0.638 0.362 0.000
L87 Transepidermal elimination disorders
0.638 0.362 0.000
L88 Pyoderma gangrenosum
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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