TreeWAS – Variant ID: rs17207370

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.997	0.003	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.990	0.010	0.000
M05 Seropositive rheumatoid arthritis	0.988	0.012	0.000
S00-S09 Injuries to the head	0.983	0.017	0.000
E11.3 With ophthalmic complications	0.982	0.018	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.980	0.020	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.963	0.037	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.963	0.037	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.962	0.038	0.000
M65-M68 Disorders of synovium and tendon	0.960	0.040	0.000
S09 Other and unspecified injuries of head	0.957	0.043	0.000
M20-M25 Other joint disorders	0.950	0.050	0.000
E10.1 With ketoacidosis	0.950	0.050	0.000
M70-M79 Other soft tissue disorders	0.950	0.050	0.000
S09.9 Unspecified injury of head	0.938	0.062	0.000
E14 Unspecified diabetes mellitus	0.937	0.063	0.000
E16 Other disorders of pancreatic internal secretion	0.934	0.066	0.000
E10.4 With neurological complications	0.932	0.068	0.000
M65 Synovitis and tenosynovitis	0.932	0.068	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.929	0.071	0.000
H53-H54 Visual disturbances and blindness	0.924	0.076	0.000
E16.2 Hypoglycaemia, unspecified	0.915	0.085	0.000
E50-E64 Other nutritional deficiencies	0.913	0.087	0.000
Chapter XX External causes of morbidity and mortality	0.911	0.089	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.904	0.096	0.000
Chapter V Mental and behavioural disorders	0.903	0.097	0.000
S02 Fracture of skull and facial bones	0.903	0.097	0.000
S00 Superficial injury of head	0.900	0.100	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.899	0.101	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.893	0.107	0.000
M25 Other joint disorders, not elsewhere classified	0.891	0.109	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.887	0.113	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.879	0.121	0.000
H53 Visual disturbances	0.873	0.127	0.000
H55-H59 Other disorders of eye and adnexa	0.872	0.128	0.000
H43-H45 Disorders of vitreous body and globe	0.871	0.129	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.870	0.130	0.000
E14.3 With ophthalmic complications	0.867	0.133	0.000
M79.8 Other specified soft tissue disorders	0.862	0.138	0.000
E10.5 With peripheral circulatory complications	0.850	0.150	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.847	0.153	0.000
F41 Other anxiety disorders	0.845	0.155	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.838	0.162	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.834	0.166	0.000
M21 Other acquired deformities of limbs	0.833	0.167	0.000
E10.2 With renal complications	0.832	0.168	0.000
E20-E35 Disorders of other endocrine glands	0.825	0.175	0.000
E53 Deficiency of other B group vitamins	0.823	0.177	0.000
H53.8 Other visual disturbances	0.821	0.179	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.819	0.181	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.817	0.183	0.000
T79-T79 Certain early complications of trauma	0.813	0.187	0.000
M65.3 Trigger finger	0.812	0.188	0.000
Chapter VI Diseases of the nervous system	0.811	0.189	0.000
S40-S49 Injuries to the shoulder and upper arm	0.810	0.190	0.000
M86-M90 Other osteopathies	0.808	0.192	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.808	0.192	0.000
F41.9 Anxiety disorder, unspecified	0.806	0.194	0.000
D50-D53 Nutritional anaemias	0.806	0.194	0.000
S90-S99 Injuries to the ankle and foot	0.805	0.195	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.802	0.198	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.801	0.199	0.000
Chapter II Neoplasms	0.800	0.200	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.798	0.202	0.000
M10 Gout	0.798	0.202	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.797	0.203	0.000
M24 Other specific joint derangements	0.794	0.206	0.000
H31 Other disorders of choroid	0.793	0.207	0.000
M79.0 Rheumatism, unspecified	0.789	0.211	0.000
S70-S79 Injuries to the hip and thigh	0.788	0.212	0.000
S00.9 Superficial injury of head, part unspecified	0.786	0.214	0.000
D68 Other coagulation defects	0.782	0.218	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.782	0.218	0.000
D60-D64 Aplastic and other anaemias	0.781	0.219	0.000
H35 Other retinal disorders	0.777	0.223	0.000
S02.1 Fracture of base of skull	0.777	0.223	0.000
M06.3 Rheumatoid nodule	0.776	0.224	0.000
S02.4 Fracture of malar and maxillary bones	0.775	0.225	0.000
H43 Disorders of vitreous body	0.774	0.226	0.000
T90 Sequelae of injuries of head	0.771	0.228	0.000
M72 Fibroblastic disorders	0.770	0.230	0.000
G90-G99 Other disorders of the nervous system	0.769	0.231	0.000
E14.9 Without complications	0.768	0.232	0.000
M79.1 Myalgia	0.762	0.238	0.000
C60-C63 Malignant neoplasms of male genital organs	0.759	0.241	0.000
E53.8 Deficiency of other specified B group vitamins	0.759	0.241	0.000
M65.1 Other infective (teno)synovitis	0.758	0.242	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.758	0.242	0.000
M35 Other systemic involvement of connective tissue	0.756	0.244	0.000
S00.8 Superficial injury of other parts of head	0.755	0.245	0.000
Chapter X Diseases of the respiratory system	0.752	0.248	0.000
S80-S89 Injuries to the knee and lower leg	0.751	0.249	0.000
Y95 Nosocomial condition	0.750	0.250	0.000
H33 Retinal detachments and breaks	0.747	0.253	0.000
J40-J47 Chronic lower respiratory diseases	0.746	0.254	0.000
H57 Other disorders of eye and adnexa	0.745	0.255	0.000
M79.5 Residual foreign body in soft tissue	0.744	0.256	0.000
E11.5 With peripheral circulatory complications	0.744	0.256	0.000
T91 Sequelae of injuries of neck and trunk	0.742	0.258	0.000
H53.4 Visual field defects	0.741	0.259	0.000
F41.1 Generalised anxiety disorder	0.741	0.259	0.000
M91-M94 Chondropathies	0.738	0.262	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.736	0.264	0.000
M21.1 Varus deformity, not elsewhere classified	0.736	0.264	0.000
M25.8 Other specified joint disorders	0.732	0.268	0.000
Chapter VIII Diseases of the ear and mastoid process	0.731	0.269	0.000
M25.0 Haemarthrosis	0.731	0.269	0.000
J47 Bronchiectasis	0.731	0.269	0.000
M66 Spontaneous rupture of synovium and tendon	0.730	0.270	0.000
M65.8 Other synovitis and tenosynovitis	0.729	0.271	0.000
D66 Hereditary factor VIII deficiency	0.728	0.272	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.727	0.273	0.000
C61 Malignant neoplasm of prostate	0.727	0.273	0.000
M65.34 Trigger finger-Hand	0.727	0.273	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.726	0.274	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.725	0.275	0.000
M00-M03 Infectious arthropathies	0.723	0.277	0.000
M06.0 Seronegative rheumatoid arthritis	0.723	0.277	0.000
X60-X84 Intentional self-harm	0.721	0.279	0.000
M25.5 Pain in joint	0.721	0.279	0.000
G93 Other disorders of brain	0.720	0.280	0.000
J45 Asthma	0.720	0.280	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.718	0.282	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.718	0.282	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.717	0.283	0.000
E10.8 With unspecified complications	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E10.0 With coma	0.717	0.283	0.000
E11.8 With unspecified complications	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
E11.6 With other specified complications	0.717	0.283	0.000
E11.1 With ketoacidosis	0.717	0.283	0.000
E11.0 With coma	0.717	0.283	0.000
E13 Other specified diabetes mellitus	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E40-E46 Malnutrition	0.717	0.283	0.000
E61 Deficiency of other nutrient elements	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.4 Inflammatory polyarthropathy	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M25.4 Effusion of joint	0.717	0.283	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H30 Chorioretinal inflammation	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
M07 Psoriatic and enteropathic arthropathies	0.714	0.286	0.000
S50-S59 Injuries to the elbow and forearm	0.713	0.286	0.001
T33-T35 Frostbite	0.709	0.290	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.290	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.709	0.290	0.000
T00-T07 Injuries involving multiple body regions	0.709	0.290	0.000
S10-S19 Injuries to the neck	0.709	0.290	0.000
M05.8 Other seropositive rheumatoid arthritis	0.708	0.291	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.708	0.291	0.000
M05.2 Rheumatoid vasculitis	0.708	0.291	0.000
M05.1 Rheumatoid lung disease	0.708	0.291	0.000
M05.0 Felty's syndrome	0.708	0.291	0.000
S02.5 Fracture of tooth	0.706	0.294	0.000
S08 Traumatic amputation of part of head	0.705	0.295	0.000
S07 Crushing injury of head	0.705	0.295	0.000
S05 Injury of eye and orbit	0.705	0.295	0.000
S04 Injury of cranial nerves	0.705	0.295	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.705	0.295	0.000
M77 Other enthesopathies	0.703	0.296	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.702	0.298	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.702	0.298	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.702	0.298	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.702	0.298	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.702	0.298	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.702	0.298	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.702	0.298	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.702	0.298	0.000
H10-H13 Disorders of conjunctiva	0.702	0.298	0.000
T66-T78 Other and unspecified effects of external causes	0.701	0.299	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.700	0.300	0.000
Chapter XXII Codes for special purposes	0.699	0.301	0.000
M34 Systemic sclerosis	0.698	0.301	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.698	0.302	0.000
J45.9 Asthma, unspecified	0.696	0.304	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.695	0.305	0.000
H55 Nystagmus and other irregular eye movements	0.694	0.306	0.000
V10-V19 Pedal cyclist injured in transport accident	0.694	0.306	0.000
D51 Vitamin B12 deficiency anaemia	0.693	0.307	0.000
C64-C68 Malignant neoplasms of urinary tract	0.693	0.307	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.692	0.307	0.000
H43.1 Vitreous haemorrhage	0.691	0.309	0.000
S40 Superficial injury of shoulder and upper arm	0.691	0.309	0.000
D55-D59 Haemolytic anaemias	0.691	0.309	0.000
E15 Nondiabetic hypoglycaemic coma	0.689	0.311	0.000
M11 Other crystal arthropathies	0.689	0.311	0.000
E11.4 With neurological complications	0.688	0.312	0.000
D68.2 Hereditary deficiency of other clotting factors	0.688	0.312	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.688	0.312	0.000
D80-D89 Certain disorders involving the immune mechanism	0.687	0.313	0.000
M35.3 Polymyalgia rheumatica	0.687	0.313	0.000
S02.10 Fracture of base of skull (closed)	0.686	0.314	0.000
S09.8 Other specified injuries of head	0.686	0.314	0.000
S09.7 Multiple injuries of head	0.686	0.314	0.000
S09.2 Traumatic rupture of ear drum	0.686	0.314	0.000
S09.1 Injury of muscle and tendon of head	0.686	0.314	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.686	0.314	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.686	0.314	0.000
S06 Intracranial injury	0.685	0.315	0.000
V80-V89 Other land transport accidents	0.685	0.315	0.000
M80-M85 Disorders of bone density and structure	0.684	0.315	0.000
M24.0 Loose body in joint	0.685	0.315	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.684	0.316	0.000
M79.7 Fibromyalgia	0.684	0.316	0.000
X50-X57 Overexertion, travel and privation	0.683	0.317	0.000
M13 Other arthritis	0.682	0.318	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.681	0.319	0.000
M33 Dermatopolymyositis	0.681	0.319	0.000
M32 Systemic lupus erythematosus	0.681	0.319	0.000
M30 Polyarteritis nodosa and related conditions	0.681	0.319	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.681	0.319	0.000
M76 Enthesopathies of lower limb, excluding foot	0.681	0.319	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.681	0.319	0.000
D69 Purpura and other haemorrhagic conditions	0.681	0.319	0.000
F43 Reaction to severe stress, and adjustment disorders	0.680	0.320	0.000
D62 Acute posthaemorrhagic anaemia	0.679	0.321	0.000
S00.3 Superficial injury of nose	0.678	0.321	0.000
F41.2 Mixed anxiety and depressive disorder	0.678	0.322	0.000
T93 Sequelae of injuries of lower limb	0.677	0.323	0.000
E55 Vitamin D deficiency	0.676	0.324	0.000
H17 Corneal scars and opacities	0.673	0.327	0.000
E14.8 With unspecified complications	0.672	0.328	0.000
E14.7 With multiple complications	0.672	0.328	0.000
E14.6 With other specified complications	0.672	0.328	0.000
E14.5 With peripheral circulatory complications	0.672	0.328	0.000
E14.4 With neurological complications	0.672	0.328	0.000
E14.2 Withrenal complications	0.672	0.328	0.000
E14.1 With ketoacidosis	0.672	0.328	0.000
E14.0 With coma	0.672	0.328	0.000
G93.6 Cerebral oedema	0.671	0.329	0.000
S02.8 Fractures of other skull and facial bones	0.671	0.329	0.000
W00-W19 Falls	0.670	0.330	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.670	0.330	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.670	0.330	0.000
E16.4 Abnormal secretion of gastrin	0.670	0.330	0.000
E16.3 Increased secretion of glucagon	0.670	0.330	0.000
E16.1 Other hypoglycaemia	0.670	0.330	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.670	0.330	0.000
Y85 Sequelae of transport accidents	0.669	0.331	0.000
M65.2 Calcific tendinitis	0.668	0.332	0.000
M65.0 Abscess of tendon sheath	0.668	0.332	0.000
Y86 Sequelae of other accidents	0.668	0.332	0.000
M25.7 Osteophyte	0.667	0.333	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.666	0.334	0.000
M79.9 Soft tissue disorder, unspecified	0.666	0.334	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.666	0.334	0.000
M79.3 Panniculitis, unspecified	0.666	0.334	0.000
M79.2 Neuralgia and neuritis, unspecified	0.666	0.334	0.000
M79.6 Pain in limb	0.665	0.335	0.000
S70 Superficial injury of hip and thigh	0.665	0.335	0.000
H34 Retinal vascular occlusions	0.663	0.337	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.659	0.341	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.657	0.343	0.000
H35.2 Other proliferative retinopathy	0.657	0.343	0.000
S00.0 Superficial injury of scalp	0.657	0.343	0.000
T92 Sequelae of injuries of upper limb	0.657	0.343	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.654	0.345	0.000
E63 Other nutritional deficiencies	0.654	0.345	0.000
E56 Other vitamin deficiencies	0.654	0.345	0.000
E51 Thiamine deficiency	0.654	0.345	0.000
E50 Vitamin A deficiency	0.654	0.345	0.000
E60 Dietary zinc deficiency	0.654	0.345	0.000
E59 Dietary selenium deficiency	0.654	0.345	0.000
E58 Dietary calcium deficiency	0.654	0.345	0.000
E54 Ascorbic acid deficiency	0.654	0.345	0.000
E52 Niacin deficiency [pellagra]	0.654	0.345	0.000
S90 Superficial injury of ankle and foot	0.654	0.346	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.653	0.347	0.000
Y35-Y36 Legal intervention and operations of war	0.653	0.347	0.000
Y10-Y34 Event of undetermined intent	0.653	0.347	0.000
Y00-Y09 Assault	0.653	0.347	0.000
X85-X99 Assault	0.653	0.347	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.653	0.347	0.000
X30-X39 Exposure to forces of nature	0.653	0.347	0.000
X20-X29 Contact with venomous animals and plants	0.653	0.347	0.000
X10-X19 Contact with heat and hot substances	0.653	0.347	0.000
X00-X09 Exposure to smoke, fire and flames	0.653	0.347	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.653	0.347	0.000
W75-W84 Other accidental threats to breathing	0.653	0.347	0.000
W65-W74 Accidental drowning and submersion	0.653	0.347	0.000
W50-W64 Exposure to animate mechanical forces	0.653	0.347	0.000
V98-V99 Other and unspecified transport accidents	0.653	0.347	0.000
V95-V97 Air and space transport accidents	0.653	0.347	0.000
V90-V94 Water transport accidents	0.653	0.347	0.000
V70-V79 Bus occupant injured in transport accident	0.653	0.347	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.653	0.347	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.653	0.347	0.000
V40-V49 Car occupant injured in transport accident	0.653	0.347	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.653	0.347	0.000
V01-V09 Pedestrian injured in transport accident	0.653	0.347	0.000
M10.9 Gout, unspecified	0.653	0.347	0.000
M71 Other bursopathies	0.653	0.347	0.000
M89 Other disorders of bone	0.652	0.348	0.000
H53.2 Diplopia	0.651	0.349	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.651	0.349	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.649	0.351	0.000
H54 Blindness and low vision	0.648	0.351	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.648	0.352	0.000
F60-F69 Disorders of adult personality and behaviour	0.648	0.352	0.000
E11.2 With renal complications	0.648	0.352	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.647	0.352	0.000
F70-F79 Mental retardation	0.647	0.352	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.647	0.352	0.000
S02.7 Multiple fractures involving skull and facial bones	0.647	0.352	0.000
S02.3 Fracture of orbital floor	0.647	0.352	0.000
S02.0 Fracture of vault of skull	0.647	0.352	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.646	0.354	0.000
S00.7 Multiple superficial injuries of head	0.645	0.354	0.000
S00.5 Superficial injury of lip and oral cavity	0.645	0.354	0.000
S00.4 Superficial injury of ear	0.645	0.354	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.645	0.354	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.645	0.355	0.000
H31.0 Chorioretinal scars	0.644	0.355	0.000
T98 Sequelae of other and unspecified effects of external causes	0.644	0.356	0.000
T95 Sequelae of burns, corrosions and frostbite	0.644	0.356	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.644	0.356	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.644	0.356	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.644	0.356	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.644	0.356	0.000
M31 Other necrotising vasculopathies	0.644	0.356	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.641	0.358	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.641	0.359	0.000
M25.9 Joint disorder, unspecified	0.639	0.361	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.639	0.361	0.000
M25.3 Other instability of joint	0.639	0.361	0.000
M25.2 Flail joint	0.639	0.361	0.000
M25.1 Fistula of joint	0.639	0.361	0.000
H57.0 Anomalies of pupillary function	0.638	0.362	0.000
E29 Testicular dysfunction	0.637	0.363	0.000
D67 Hereditary factor IX deficiency	0.636	0.364	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.636	0.364	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.636	0.364	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.635	0.365	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.635	0.365	0.000
H44 Disorders of globe	0.634	0.366	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.634	0.366	0.000
G91 Hydrocephalus	0.634	0.366	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.633	0.367	0.000
T17 Foreign body in respiratory tract	0.633	0.367	0.000
V20-V29 Motorcycle rider injured in transport accident	0.632	0.368	0.000
F80-F89 Disorders of psychological development	0.630	0.370	0.000
H43.3 Other vitreous opacities	0.630	0.370	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.629	0.371	0.000
M67 Other disorders of synovium and tendon	0.627	0.372	0.000
H53.6 Night blindness	0.626	0.374	0.000
H53.5 Colour vision deficiencies	0.626	0.374	0.000
H53.3 Other disorders of binocular vision	0.626	0.374	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.625	0.375	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.625	0.375	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.625	0.375	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.625	0.375	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.624	0.376	0.000
M21.3 Wrist or foot drop (acquired)	0.624	0.376	0.000
E27 Other disorders of adrenal gland	0.624	0.376	0.000
F48 Other neurotic disorders	0.624	0.376	0.000
F44 Dissociative [conversion] disorders	0.624	0.376	0.000
F42 Obsessive-compulsive disorder	0.624	0.376	0.000
S00.1 Contusion of eyelid and periocular area	0.623	0.377	0.000
H53.1 Subjective visual disturbances	0.621	0.378	0.000
E22 Hyperfunction of pituitary gland	0.621	0.379	0.000
C71 Malignant neoplasm of brain	0.620	0.380	0.000
S02.2 Fracture of nasal bones	0.620	0.380	0.000
D45 Polycythaemia vera	0.619	0.381	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.618	0.382	0.000
M79.88 Other specified soft tissue disorders (Other)	0.618	0.382	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.618	0.382	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.618	0.382	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.618	0.382	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.618	0.382	0.000
M87 Osteonecrosis	0.617	0.383	0.000
M25.06 Haemarthrosis (Lower leg)	0.616	0.384	0.000
M06.34 Rheumatoid nodule (Hand)	0.616	0.384	0.000
D68.5 Primary Thrombophilia	0.614	0.385	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.614	0.386	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.612	0.388	0.000
M79.10 Myalgia (Multiple sites)	0.612	0.388	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.612	0.388	0.000
M25.52 Pain in joint (Upper arm)	0.611	0.389	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.611	0.389	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.610	0.390	0.000
F99-F99 Unspecified mental disorder	0.609	0.391	0.000
D47.1 Chronic myeloproliferative disease	0.607	0.393	0.000
F41.8 Other specified anxiety disorders	0.606	0.394	0.000
F41.3 Other mixed anxiety disorders	0.606	0.394	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.606	0.394	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.606	0.394	0.000
S02.6 Fracture of mandible	0.604	0.396	0.000
H35.8 Other specified retinal disorders	0.604	0.396	0.000
S92 Fracture of foot, except ankle	0.604	0.396	0.000
T90.9 Sequelae of unspecified injury of head	0.603	0.397	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.603	0.397	0.000
J42 Unspecified chronic bronchitis	0.601	0.398	0.000
M21.0 Valgus deformity, not elsewhere classified	0.601	0.399	0.000
D75 Other diseases of blood and blood-forming organs	0.601	0.399	0.000
T90.5 Sequelae of intracranial injury	0.601	0.399	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.600	0.399	0.000
M22 Disorders of patella	0.600	0.399	0.000
S51 Open wound of forearm	0.599	0.400	0.000
Q50-Q56 Congenital malformations of genital organs	0.599	0.401	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.599	0.401	0.000
G70-G73 Diseases of myoneural junction and muscle	0.599	0.401	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.597	0.402	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.597	0.403	0.000
M21.9 Acquired deformity of limb, unspecified	0.597	0.403	0.000
M21.8 Other specified acquired deformities of limbs	0.597	0.403	0.000
M21.7 Unequal limb length (acquired)	0.597	0.403	0.000
M21.6 Other acquired deformities of ankle and foot	0.597	0.403	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.597	0.403	0.000
M21.4 Flat foot [pes planus] (acquired)	0.597	0.403	0.000
M21.2 Flexion deformity	0.597	0.403	0.000
H20 Iridocyclitis	0.597	0.403	0.000
H53.9 Visual disturbance, unspecified	0.596	0.403	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.596	0.404	0.000
F40 Phobic anxiety disorders	0.596	0.404	0.000
H33.2 Serous retinal detachment	0.594	0.406	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.593	0.407	0.000
J60-J70 Lung diseases due to external agents	0.593	0.407	0.000
M40-M43 Deforming dorsopathies	0.592	0.407	0.000
S82 Fracture of lower leg, including ankle	0.592	0.408	0.000
F45 Somatoform disorders	0.592	0.408	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.592	0.408	0.000
E34 Other endocrine disorders	0.592	0.408	0.000
E32 Diseases of thymus	0.592	0.408	0.000
E31 Polyglandular dysfunction	0.592	0.408	0.000
E30 Disorders of puberty, not elsewhere classified	0.592	0.408	0.000
E26 Hyperaldosteronism	0.592	0.408	0.000
E25 Adrenogenital disorders	0.592	0.408	0.000
E24 Cushing's syndrome	0.592	0.408	0.000
E20 Hypoparathyroidism	0.592	0.408	0.000
H35.6 Retinal haemorrhage	0.591	0.409	0.000
C51-C58 Malignant neoplasms of female genital organs	0.590	0.409	0.000
T91.3 Sequelae of injury of spinal cord	0.590	0.410	0.000
E53.9 Vitamin B deficiency, unspecified	0.590	0.410	0.000
E53.1 Pyridoxine deficiency	0.590	0.410	0.000
E53.0 Riboflavin deficiency	0.590	0.410	0.000
M86 Osteomyelitis	0.590	0.410	0.000
M25.46 Effusion of joint (Lower leg)	0.590	0.410	0.000
M79.18 Myalgia (Other)	0.589	0.411	0.000
H21 Other disorders of iris and ciliary body	0.589	0.411	0.000
S80 Superficial injury of lower leg	0.588	0.412	0.000
E23 Hypofunction and other disorders of pituitary gland	0.588	0.412	0.000
T91.1 Sequelae of fracture of spine	0.588	0.412	0.000
W20-W49 Exposure to inanimate mechanical forces	0.587	0.412	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.587	0.412	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.587	0.412	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.587	0.412	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.587	0.412	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.587	0.412	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.587	0.412	0.000
C67 Malignant neoplasm of bladder	0.586	0.414	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.586	0.414	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.586	0.414	0.000
Y98 Lifestyle-related condition	0.586	0.414	0.000
Y97 Environmental-pollution-related condition	0.586	0.414	0.000
Y96 Work-related condition	0.586	0.414	0.000
H57.8 Other specified disorders of eye and adnexa	0.585	0.415	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.584	0.416	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.583	0.417	0.000
M25.84 Other specified joint disorders (Hand)	0.583	0.417	0.000
M65.39 Trigger finger-Site unspec	0.582	0.418	0.000
M65.38 Trigger finger-Other	0.582	0.418	0.000
M65.37 Trigger finger-Ankle/foot	0.582	0.418	0.000
M65.36 Trigger finger-Lower leg	0.582	0.418	0.000
M65.35 Trigger finger-Pelvic/thigh	0.582	0.418	0.000
M65.33 Trigger finger-Forearm	0.582	0.418	0.000
M65.32 Trigger finger-Upper arm	0.582	0.418	0.000
M65.31 Trigger finger-Shldr region	0.582	0.418	0.000
M65.30 Trigger finger-Mult sites	0.582	0.418	0.000
T90.4 Sequelae of injury of eye and orbit	0.582	0.418	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.581	0.419	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations