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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17215305
log Bayes Factor = 12.2436
Chromosome 19   position 19,293,252  (GRCh37) Explore rs17215305 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.992 0.008 0.000
N17-N19 Renal failure
0.989 0.011 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.989 0.011 0.000
Chapter II Neoplasms
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
G47 Sleep disorders
0.984 0.016 0.000
R26 Abnormalities of gait and mobility
0.980 0.020 0.000
D10-D36 Benign neoplasms
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
N18 Chronic renal failure
0.972 0.028 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.971 0.029 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.971 0.029 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.968 0.032 0.000
E70-E90 Metabolic disorders
0.966 0.034 0.000
M45-M49 Spondylopathies
0.962 0.038 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.962 0.038 0.000
D12.6 Colon, unspecified
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.951 0.049 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.948 0.052 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
G47.9 Sleep disorder, unspecified
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.941 0.059 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.937 0.063 0.000
M47 Spondylosis
0.936 0.064 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
D12.2 Ascending colon
0.929 0.071 0.000
M70-M79 Other soft tissue disorders
0.929 0.071 0.000
M47.8 Other spondylosis
0.928 0.072 0.000
E11 Non-insulin-dependent diabetes mellitus
0.927 0.073 0.000
N18.9 Chronic renal failure, unspecified
0.920 0.080 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.919 0.081 0.000
N40-N51 Diseases of male genital organs
0.914 0.086 0.000
N17 Acute renal failure
0.913 0.087 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
G47.3 Sleep apnoea
0.908 0.092 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.908 0.092 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.907 0.093 0.000
E10 Insulin-dependent diabetes mellitus
0.897 0.103 0.000
G40 Epilepsy
0.897 0.103 0.000
Chapter IX Diseases of the circulatory system
0.894 0.106 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.893 0.107 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.892 0.108 0.000
M47.82 Other spondylosis (Cervical region)
0.892 0.108 0.000
G90-G99 Other disorders of the nervous system
0.890 0.110 0.000
M50-M54 Other dorsopathies
0.887 0.113 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.887 0.113 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.885 0.115 0.000
L60-L75 Disorders of skin appendages
0.883 0.117 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.881 0.119 0.000
T93 Sequelae of injuries of lower limb
0.879 0.121 0.000
R29.6 Tendency to fall, not elsewhere classified
0.878 0.122 0.000
R94 Abnormal results of function studies
0.876 0.124 0.000
R27 Other lack of coordination
0.874 0.126 0.000
D25 Leiomyoma of uterus
0.873 0.127 0.000
N19 Unspecified renal failure
0.871 0.129 0.000
T92 Sequelae of injuries of upper limb
0.869 0.131 0.000
R94.5 Abnormal results of liver function studies
0.867 0.133 0.000
M79.8 Other specified soft tissue disorders
0.863 0.137 0.000
N17.9 Acute renal failure, unspecified
0.859 0.141 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.858 0.142 0.000
H90-H95 Other disorders of ear
0.857 0.142 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.855 0.145 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.854 0.146 0.000
M54 Dorsalgia
0.852 0.148 0.000
N00-N08 Glomerular diseases
0.851 0.149 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.844 0.156 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.843 0.157 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.842 0.158 0.000
N18.5 Chronic kidney disease, stage 5
0.838 0.162 0.000
R50-R69 General symptoms and signs
0.838 0.162 0.000
I05-I09 Chronic rheumatic heart diseases
0.837 0.163 0.000
D24 Benign neoplasm of breast
0.836 0.164 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.835 0.165 0.000
E11.3 With ophthalmic complications
0.834 0.166 0.000
G43 Migraine
0.832 0.168 0.000
H65-H75 Diseases of middle ear and mastoid
0.830 0.170 0.000
R05 Cough
0.829 0.171 0.000
L72.1 Trichilemmal cyst
0.828 0.172 0.000
R69 Unknown and unspecified causes of morbidity
0.822 0.178 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.819 0.181 0.000
D12.4 Descending colon
0.819 0.181 0.000
E50-E64 Other nutritional deficiencies
0.817 0.183 0.000
G93 Other disorders of brain
0.813 0.187 0.000
Q60-Q64 Congenital malformations of the urinary system
0.813 0.187 0.000
Y52 Agents primarily affecting the cardiovascular system
0.812 0.188 0.000
N18.2 Chronic kidney disease, stage 2
0.812 0.188 0.000
E27 Other disorders of adrenal gland
0.810 0.190 0.000
N18.0 End-stage renal disease
0.810 0.190 0.000
E87.7 Fluid overload
0.807 0.193 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.805 0.195 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.804 0.196 0.000
N45 Orchitis and epididymitis
0.803 0.197 0.000
Y42.5 Other oestrogens and progestogens
0.800 0.200 0.000
N75 Diseases of Bartholin's gland
0.798 0.202 0.000
T92.1 Sequelae of fracture of arm
0.797 0.203 0.000
E87.0 Hyperosmolality and hypernatraemia
0.797 0.203 0.000
D25.9 Leiomyoma of uterus, unspecified
0.796 0.204 0.000
S80-S89 Injuries to the knee and lower leg
0.796 0.204 0.000
E00-E07 Disorders of thyroid gland
0.795 0.205 0.000
G35 Multiple sclerosis
0.794 0.206 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.793 0.207 0.000
E10.3 With ophthalmic complications
0.792 0.208 0.000
W20-W49 Exposure to inanimate mechanical forces
0.791 0.209 0.000
T91 Sequelae of injuries of neck and trunk
0.791 0.209 0.000
I71 Aortic aneurysm and dissection
0.790 0.210 0.000
S40-S49 Injuries to the shoulder and upper arm
0.790 0.210 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.790 0.210 0.000
M48 Other spondylopathies
0.790 0.210 0.000
Y40 Systemic antibiotics
0.789 0.211 0.000
I08 Multiple valve diseases
0.789 0.211 0.000
Q80-Q89 Other congenital malformations
0.787 0.213 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.785 0.215 0.000
N76 Other inflammation of vagina and vulva
0.784 0.216 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.782 0.218 0.000
H92 Otalgia and effusion of ear
0.781 0.218 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.781 0.219 0.000
N50 Other disorders of male genital organs
0.781 0.219 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.781 0.219 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.780 0.220 0.000
L20-L30 Dermatitis and eczema
0.779 0.221 0.000
N43 Hydrocele and spermatocele
0.779 0.221 0.000
M46 Other inflammatory spondylopathies
0.778 0.222 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.777 0.223 0.000
Chapter I Certain infectious and parasitic diseases
0.777 0.223 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.777 0.223 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.777 0.223 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.776 0.224 0.000
E13 Other specified diabetes mellitus
0.775 0.225 0.000
L89 Decubitus ulcer
0.774 0.226 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.774 0.226 0.000
E14 Unspecified diabetes mellitus
0.773 0.227 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.773 0.227 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.772 0.228 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.770 0.230 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.769 0.231 0.000
M65-M68 Disorders of synovium and tendon
0.769 0.231 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.767 0.232 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.764 0.236 0.000
W50-W64 Exposure to animate mechanical forces
0.764 0.236 0.000
R52 Pain, not elsewhere classified
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
D35.1 Parathyroid gland
0.761 0.239 0.000
G47.8 Other sleep disorders
0.761 0.239 0.000
R27.0 Ataxia, unspecified
0.761 0.239 0.000
R02 Gangrene, not elsewhere classified
0.758 0.242 0.000
H65 Nonsuppurative otitis media
0.757 0.243 0.000
T93.2 Sequelae of other fractures of lower limb
0.757 0.243 0.000
Y43 Primarily systemic agents
0.756 0.244 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.756 0.244 0.000
D12.3 Transverse colon
0.755 0.245 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.755 0.245 0.000
N25-N29 Other disorders of kidney and ureter
0.754 0.246 0.000
Chapter X Diseases of the respiratory system
0.754 0.246 0.000
M79.2 Neuralgia and neuritis, unspecified
0.752 0.248 0.000
N72 Inflammatory disease of cervix uteri
0.751 0.248 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.751 0.249 0.000
D35.2 Pituitary gland
0.750 0.250 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.750 0.250 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.749 0.251 0.000
M54.9 Dorsalgia, unspecified
0.747 0.253 0.000
D12.9 Anus and anal canal
0.746 0.254 0.000
E83 Disorders of mineral metabolism
0.746 0.254 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.746 0.254 0.000
Q50-Q56 Congenital malformations of genital organs
0.746 0.254 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
G41 Status epilepticus
0.740 0.260 0.000
D80-D89 Certain disorders involving the immune mechanism
0.739 0.261 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.739 0.261 0.000
D34 Benign neoplasm of thyroid gland
0.738 0.261 0.000
E11.1 With ketoacidosis
0.738 0.262 0.000
N99-N99 Other disorders of the genitourinary system
0.738 0.262 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
L85 Other epidermal thickening
0.737 0.263 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.736 0.264 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
T90 Sequelae of injuries of head
0.735 0.265 0.000
N73 Other female pelvic inflammatory diseases
0.735 0.265 0.000
G43.9 Migraine, unspecified
0.734 0.266 0.000
D25.0 Submucous leiomyoma of uterus
0.734 0.266 0.000
G20-G26 Extrapyramidal and movement disorders
0.734 0.266 0.000
D26 Other benign neoplasms of uterus
0.733 0.267 0.000
M79.6 Pain in limb
0.732 0.268 0.000
M60-M63 Disorders of muscles
0.732 0.268 0.000
E16 Other disorders of pancreatic internal secretion
0.732 0.268 0.000
R47-R49 Symptoms and signs involving speech and voice
0.728 0.271 0.000
N70 Salpingitis and oophoritis
0.728 0.272 0.000
G30-G32 Other degenerative diseases of the nervous system
0.728 0.272 0.000
R26.0 Ataxic gait
0.727 0.273 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.727 0.273 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
D46 Myelodysplastic syndromes
0.725 0.275 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.725 0.275 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.724 0.276 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.723 0.277 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
M54.5 Low back pain
0.723 0.277 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.722 0.278 0.000
J00-J06 Acute upper respiratory infections
0.720 0.280 0.000
M80-M85 Disorders of bone density and structure
0.720 0.280 0.000
R80 Isolated proteinuria
0.720 0.280 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
M47.86 Other spondylosis (Lumbar region)
0.720 0.280 0.000
E11.5 With peripheral circulatory complications
0.719 0.281 0.000
E10.2 With renal complications
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.717 0.283 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.717 0.283 0.000
I60-I69 Cerebrovascular diseases
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.715 0.285 0.000
D23 Other benign neoplasms of skin
0.715 0.285 0.000
H80-H83 Diseases of inner ear
0.714 0.286 0.000
H92.0 Otalgia
0.714 0.286 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.711 0.289 0.000
E87.5 Hyperkalaemia
0.711 0.289 0.000
M54.6 Pain in thoracic spine
0.709 0.291 0.000
R29.4 Clicking hip
0.709 0.291 0.000
R29.3 Abnormal posture
0.709 0.291 0.000
R29.2 Abnormal reflex
0.709 0.291 0.000
R29.1 Meningismus
0.709 0.291 0.000
R29.0 Tetany
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
E40-E46 Malnutrition
0.708 0.291 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
C83.3 Large cell (diffuse)
0.708 0.292 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.707 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.706 0.293 0.000
E12 Malnutrition-related diabetes mellitus
0.706 0.294 0.000
N04 Nephrotic syndrome
0.706 0.294 0.000
I77 Other disorders of arteries and arterioles
0.706 0.294 0.000
E11.6 With other specified complications
0.706 0.294 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
G47.4 Narcolepsy and cataplexy
0.705 0.295 0.000
G47.2 Disorders of the sleep-wake schedule
0.705 0.295 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.705 0.295 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.705 0.295 0.000
R26.1 Paralytic gait
0.702 0.298 0.000
D31 Benign neoplasm of eye and adnexa
0.701 0.299 0.000
D30 Benign neoplasm of urinary organs
0.701 0.299 0.000
D29 Benign neoplasm of male genital organs
0.701 0.299 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.701 0.299 0.000
D19 Benign neoplasm of mesothelial tissue
0.701 0.299 0.000
D16 Benign neoplasm of bone and articular cartilage
0.701 0.299 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.701 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
S81 Open wound of lower leg
0.701 0.299 0.000
M79.5 Residual foreign body in soft tissue
0.700 0.300 0.000
E34 Other endocrine disorders
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
I05 Rheumatic mitral valve diseases
0.698 0.302 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.698 0.302 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
C15-C26 Malignant neoplasms of digestive organs
0.697 0.303 0.000
N18.8 Other chronic renal failure
0.697 0.303 0.000
N18.1 Chronic kidney disease, stage 1
0.697 0.303 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.697 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
Y42.7 Androgens and anabolic congeners
0.696 0.304 0.000
M47.1 Other spondylosis with myelopathy
0.696 0.304 0.000
D12.1 Appendix
0.696 0.304 0.000
Q61 Cystic kidney disease
0.695 0.305 0.000
R52.1 Chronic intractable pain
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.694 0.305 0.000
D00-D09 In situ neoplasms
0.695 0.305 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.694 0.305 0.000
T92.0 Sequelae of open wound of upper limb
0.694 0.306 0.000
E85 Amyloidosis
0.693 0.307 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E74 Other disorders of carbohydrate metabolism
0.693 0.307 0.000
E73 Lactose intolerance
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
E10.5 With peripheral circulatory complications
0.692 0.308 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.691 0.309 0.000
E83.5 Disorders of calcium metabolism
0.691 0.309 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.309 0.000
M49 Spondylopathies in diseases classified elsewhere
0.690 0.310 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.690 0.310 0.000
Y59 Other and unspecified vaccines and biological substances
0.689 0.310 0.000
Y58 Bacterial vaccines
0.689 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.689 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.689 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.689 0.310 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.689 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.689 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.689 0.310 0.000
N02 Recurrent and persistent haematuria
0.688 0.312 0.000
G93.3 Postviral fatigue syndrome
0.687 0.313 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.686 0.314 0.000
I63 Cerebral infarction
0.686 0.314 0.000
E53 Deficiency of other B group vitamins
0.686 0.314 0.000
R64 Cachexia
0.685 0.315 0.000
H65.3 Chronic mucoid otitis media
0.684 0.316 0.000
S90-S99 Injuries to the ankle and foot
0.683 0.317 0.000
I08.0 Disorders of both mitral and aortic valves
0.683 0.317 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.682 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
T33-T35 Frostbite
0.682 0.318 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.682 0.318 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.682 0.318 0.000
T00-T07 Injuries involving multiple body regions
0.682 0.318 0.000
S10-S19 Injuries to the neck
0.682 0.318 0.000
N43.3 Hydrocele, unspecified
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.681 0.319 0.000
E11.4 With neurological complications
0.681 0.319 0.000
R27.8 Other and unspecified lack of coordination
0.681 0.319 0.000
D35.0 Adrenal gland
0.681 0.319 0.000
D45 Polycythaemia vera
0.680 0.320 0.000
D86 Sarcoidosis
0.680 0.320 0.000
E87.4 Mixed disorder of acid-base balance
0.680 0.320 0.000
E87.3 Alkalosis
0.680 0.320 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.679 0.321 0.000
D11 Benign neoplasm of major salivary glands
0.678 0.322 0.000
E11.9 Without complications
0.678 0.322 0.000
J03 Acute tonsillitis
0.678 0.322 0.000
R26.3 Immobility
0.678 0.322 0.000
N75.0 Cyst of Bartholin's gland
0.677 0.323 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.677 0.323 0.000
R63 Symptoms and signs concerning food and fluid intake
0.677 0.323 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.325 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.675 0.325 0.000
M47.89 Other spondylosis (Site unspecified)
0.675 0.325 0.000
T98 Sequelae of other and unspecified effects of external causes
0.675 0.325 0.000
T95 Sequelae of burns, corrosions and frostbite
0.675 0.325 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.675 0.325 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.675 0.325 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.675 0.325 0.000
G96 Other disorders of central nervous system
0.674 0.326 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.673 0.326 0.000
M79.0 Rheumatism, unspecified
0.673 0.327 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.672 0.327 0.000
E78.5 Hyperlipidaemia, unspecified
0.672 0.328 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.672 0.328 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.672 0.328 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.671 0.329 0.000
N71 Inflammatory disease of uterus, except cervix
0.670 0.330 0.000
E21.3 Hyperparathyroidism, unspecified
0.670 0.330 0.000
Y40.3 Macrolides
0.670 0.330 0.000
Q82 Other congenital malformations of skin
0.670 0.330 0.000
N48 Other disorders of penis
0.669 0.331 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.669 0.331 0.000
C64-C68 Malignant neoplasms of urinary tract
0.669 0.331 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.669 0.331 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.669 0.331 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.669 0.331 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.669 0.331 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.669 0.331 0.000
S80 Superficial injury of lower leg
0.669 0.331 0.000
E27.1 Primary adrenocortical insufficiency
0.667 0.333 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.333 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.667 0.333 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.333 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.666 0.333 0.000
Y54.3 Benzothiadiazine derivatives
0.666 0.333 0.000
M71 Other bursopathies
0.666 0.333 0.000
M76 Enthesopathies of lower limb, excluding foot
0.666 0.334 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.666 0.334 0.000
M48.0 Spinal stenosis
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.666 0.334 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.666 0.334 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.666 0.334 0.000
M47.84 Other spondylosis (Thoracic region)
0.666 0.334 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.666 0.334 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.666 0.334 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.666 0.334 0.000
E11.8 With unspecified complications
0.664 0.336 0.000
E11.7 With multiple complications
0.664 0.336 0.000
E11.0 With coma
0.664 0.336 0.000
M10 Gout
0.664 0.336 0.000
G40.9 Epilepsy, unspecified
0.664 0.336 0.000
D37.4 Colon
0.664 0.336 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.662 0.337 0.000
I08.8 Other multiple valve diseases
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.338 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.662 0.338 0.000
N76.0 Acute vaginitis
0.662 0.338 0.000
H93 Other disorders of ear, not elsewhere classified
0.662 0.338 0.000
L81 Other disorders of pigmentation
0.661 0.339 0.000
D25.2 Subserosal leiomyoma of uterus
0.661 0.339 0.000
R01 Cardiac murmurs and other cardiac sounds
0.661 0.339 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.661 0.339 0.000
S70-S79 Injuries to the hip and thigh
0.660 0.339 0.000
M79.62 Pain in limb (Upper arm)
0.660 0.340 0.000
I78 Diseases of capillaries
0.660 0.340 0.000
M54.1 Radiculopathy
0.659 0.341 0.000
G37 Other demyelinating diseases of central nervous system
0.659 0.341 0.000
S86 Injury of muscle and tendon at lower leg level
0.658 0.342 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.657 0.343 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.656 0.344 0.000
N46 Male infertility
0.656 0.344 0.000
N44 Torsion of testis
0.656 0.344 0.000
E22 Hyperfunction of pituitary gland
0.655 0.344 0.000
E88 Other metabolic disorders
0.655 0.344 0.000
H60-H62 Diseases of external ear
0.655 0.345 0.000
N17.8 Other acute renal failure
0.655 0.345 0.000
N17.2 Acute renal failure with medullary necrosis
0.655 0.345 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.655 0.345 0.000
N17.0 Acute renal failure with tubular necrosis
0.655 0.345 0.000
M53 Other dorsopathies, not elsewhere classified
0.654 0.346 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.654 0.346 0.000
M40-M43 Deforming dorsopathies
0.654 0.346 0.000
I63.9 Cerebral infarction, unspecified
0.654 0.346 0.000
N50.0 Atrophy of testis
0.653 0.347 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.653 0.347 0.000
E32 Diseases of thymus
0.653 0.347 0.000
E31 Polyglandular dysfunction
0.653 0.347 0.000
E30 Disorders of puberty, not elsewhere classified
0.653 0.347 0.000
E26 Hyperaldosteronism
0.653 0.347 0.000
E25 Adrenogenital disorders
0.653 0.347 0.000
E24 Cushing's syndrome
0.653 0.347 0.000
E20 Hypoparathyroidism
0.653 0.347 0.000
G91 Hydrocephalus
0.652 0.348 0.000
E16.2 Hypoglycaemia, unspecified
0.652 0.348 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.651 0.349 0.000
Y42.9 Other and unspecified hormone antagonists
0.651 0.349 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.651 0.349 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.651 0.349 0.000
Y42.4 Oral contraceptives
0.651 0.349 0.000
Y42.2 Antithyroid drugs
0.651 0.349 0.000
Y42.1 Thyroid hormones and substitutes
0.651 0.349 0.000
M79.9 Soft tissue disorder, unspecified
0.651 0.349 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.651 0.349 0.000
M79.3 Panniculitis, unspecified
0.651 0.349 0.000
M79.1 Myalgia
0.651 0.349 0.000
W29 Contact with other powered hand tools and household machinery
0.650 0.349 0.000
M54.2 Cervicalgia
0.650 0.350 0.000
E10.1 With ketoacidosis
0.650 0.350 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.649 0.350 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.649 0.351 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.649 0.351 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.649 0.351 0.000
J03.9 Acute tonsillitis, unspecified
0.648 0.352 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.648 0.352 0.000
M77 Other enthesopathies
0.647 0.353 0.000
L82 Seborrhoeic keratosis
0.647 0.353 0.000
I74 Arterial embolism and thrombosis
0.647 0.353 0.000
H74 Other disorders of middle ear and mastoid
0.647 0.353 0.000
D50-D53 Nutritional anaemias
0.647 0.353 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.646 0.353 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.646 0.354 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.646 0.354 0.000
M67 Other disorders of synovium and tendon
0.646 0.354 0.000
D41.0 Kidney
0.645 0.355 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.645 0.355 0.000
E11.2 With renal complications
0.644 0.356 0.000
B07 Viral warts
0.644 0.356 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.644 0.356 0.000
E10.8 With unspecified complications
0.643 0.356 0.000
E10.7 With multiple complications
0.643 0.356 0.000
E10.6 With other specified complications
0.643 0.356 0.000
E10.0 With coma
0.643 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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