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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17636747
log Bayes Factor = 13.8903
Chromosome 2   position 105,877,870  (GRCh37) Explore rs17636747 on Ensembl!
Variant rs17636747 is listed in the   GWAS Catalog   ⇪
Variant rs17636747 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.994 0.006 0.000
M25 Other joint disorders, not elsewhere classified
0.993 0.007 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.993 0.007 0.000
M23 Internal derangement of knee
0.991 0.009 0.000
M25.5 Pain in joint
0.990 0.010 0.000
Y86 Sequelae of other accidents
0.987 0.013 0.000
Chapter II Neoplasms
0.981 0.019 0.000
Chapter XIV Diseases of the genitourinary system
0.977 0.023 0.000
M35 Other systemic involvement of connective tissue
0.976 0.024 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.976 0.024 0.000
S00-S09 Injuries to the head
0.975 0.025 0.000
D10-D36 Benign neoplasms
0.968 0.032 0.000
N30-N39 Other diseases of urinary system
0.967 0.033 0.000
L82 Seborrhoeic keratosis
0.965 0.035 0.000
N35 Urethral stricture
0.963 0.037 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.962 0.038 0.000
N35.9 Urethral stricture, unspecified
0.959 0.041 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.958 0.042 0.000
M35.3 Polymyalgia rheumatica
0.957 0.043 0.000
M70-M79 Other soft tissue disorders
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
S40-S49 Injuries to the shoulder and upper arm
0.947 0.053 0.000
N20-N23 Urolithiasis
0.944 0.056 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.943 0.057 0.000
S00 Superficial injury of head
0.934 0.066 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.934 0.066 0.000
M50-M54 Other dorsopathies
0.933 0.067 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.931 0.069 0.000
M65-M68 Disorders of synovium and tendon
0.930 0.070 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.927 0.073 0.000
D22 Melanocytic naevi
0.924 0.076 0.000
M22 Disorders of patella
0.923 0.077 0.000
D00-D09 In situ neoplasms
0.923 0.077 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.921 0.079 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.921 0.079 0.000
N23 Unspecified renal colic
0.920 0.080 0.000
M25.57 Pain in joint (Ankle and foot)
0.915 0.085 0.000
M86-M90 Other osteopathies
0.914 0.086 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.913 0.087 0.000
M31 Other necrotising vasculopathies
0.912 0.088 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.911 0.089 0.000
D05 Carcinoma in situ of breast
0.901 0.099 0.000
M34 Systemic sclerosis
0.898 0.102 0.000
G20-G26 Extrapyramidal and movement disorders
0.898 0.102 0.000
M23.3 Other meniscus derangements
0.897 0.103 0.000
L84 Corns and callosities
0.896 0.104 0.000
D12.6 Colon, unspecified
0.892 0.108 0.000
L89 Decubitus ulcer
0.888 0.112 0.000
E20-E35 Disorders of other endocrine glands
0.884 0.116 0.000
C64-C68 Malignant neoplasms of urinary tract
0.884 0.116 0.000
M25.50 Pain in joint (Multiple sites)
0.883 0.116 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.882 0.118 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.879 0.121 0.000
M80-M85 Disorders of bone density and structure
0.878 0.122 0.000
S32 Fracture of lumbar spine and pelvis
0.873 0.127 0.000
Chapter VIII Diseases of the ear and mastoid process
0.872 0.128 0.000
D12.8 Rectum
0.871 0.129 0.000
M79.7 Fibromyalgia
0.867 0.133 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.867 0.133 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.864 0.136 0.000
S10-S19 Injuries to the neck
0.861 0.139 0.000
M25.52 Pain in joint (Upper arm)
0.855 0.145 0.000
S00.9 Superficial injury of head, part unspecified
0.853 0.147 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.852 0.148 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.851 0.149 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.850 0.150 0.000
G20 Parkinson's disease
0.850 0.150 0.000
S40 Superficial injury of shoulder and upper arm
0.849 0.151 0.000
M24 Other specific joint derangements
0.845 0.155 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.844 0.156 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.843 0.157 0.000
D12.4 Descending colon
0.841 0.159 0.000
M25.51 Pain in joint (Shoulder region)
0.839 0.161 0.000
M21 Other acquired deformities of limbs
0.839 0.161 0.000
M23.8 Other internal derangements of knee
0.836 0.164 0.000
M32 Systemic lupus erythematosus
0.833 0.167 0.000
L60-L75 Disorders of skin appendages
0.832 0.168 0.000
T81 Complications of procedures, not elsewhere classified
0.831 0.169 0.000
M87 Osteonecrosis
0.831 0.169 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.830 0.170 0.000
M22.2 Patellofemoral disorders
0.823 0.177 0.000
D12.7 Rectosigmoid junction
0.821 0.179 0.000
M67 Other disorders of synovium and tendon
0.821 0.179 0.000
S02 Fracture of skull and facial bones
0.820 0.180 0.000
Y88 Sequelae of surgical and medical care as external cause
0.820 0.180 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.820 0.180 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.815 0.185 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.813 0.187 0.000
L50-L54 Urticaria and erythema
0.812 0.188 0.000
C67 Malignant neoplasm of bladder
0.812 0.188 0.000
Y40 Systemic antibiotics
0.811 0.189 0.000
S05 Injury of eye and orbit
0.809 0.191 0.000
M65 Synovitis and tenosynovitis
0.808 0.192 0.000
T92 Sequelae of injuries of upper limb
0.807 0.193 0.000
D12.9 Anus and anal canal
0.806 0.194 0.000
T40.2 Other opioids
0.804 0.196 0.000
M79.2 Neuralgia and neuritis, unspecified
0.803 0.197 0.000
M31.6 Other giant cell arteritis
0.802 0.198 0.000
M54 Dorsalgia
0.801 0.199 0.000
S00.0 Superficial injury of scalp
0.798 0.202 0.000
D12.2 Ascending colon
0.796 0.204 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.796 0.204 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.795 0.205 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.795 0.205 0.000
M79.1 Myalgia
0.794 0.206 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.793 0.207 0.000
M79.79 Fibromyalgia (Site unspecified)
0.793 0.207 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.791 0.209 0.000
X60-X84 Intentional self-harm
0.791 0.209 0.000
S01 Open wound of head
0.790 0.210 0.000
L83 Acanthosis nigricans
0.789 0.211 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.788 0.212 0.000
D32 Benign neoplasm of meninges
0.788 0.212 0.000
M23.1 Discoid meniscus (congenital)
0.786 0.214 0.000
H65-H75 Diseases of middle ear and mastoid
0.786 0.214 0.000
L93 Lupus erythematosus
0.785 0.215 0.000
M51 Other intervertebral disk disorders
0.784 0.216 0.000
T93 Sequelae of injuries of lower limb
0.784 0.216 0.000
M91-M94 Chondropathies
0.784 0.216 0.000
E28 Ovarian dysfunction
0.781 0.219 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.781 0.219 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.778 0.222 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.778 0.222 0.000
M25.59 Pain in joint (Site unspecified)
0.778 0.222 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.776 0.224 0.000
M75 Shoulder lesions
0.776 0.224 0.000
N20 Calculus of kidney and ureter
0.772 0.228 0.000
N36 Other disorders of urethra
0.771 0.229 0.000
D12.3 Transverse colon
0.770 0.230 0.000
N35.8 Other urethral stricture
0.769 0.231 0.000
M25.3 Other instability of joint
0.769 0.231 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.768 0.231 0.000
S80-S89 Injuries to the knee and lower leg
0.765 0.235 0.000
M31.3 Wegener's granulomatosis
0.765 0.235 0.000
C60-C63 Malignant neoplasms of male genital organs
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.762 0.238 0.000
M34.9 Systemic sclerosis, unspecified
0.760 0.240 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.759 0.241 0.000
W50-W64 Exposure to animate mechanical forces
0.757 0.242 0.000
H60-H62 Diseases of external ear
0.757 0.243 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.757 0.243 0.000
D04 Carcinoma in situ of skin
0.756 0.244 0.000
M50 Cervical disk disorders
0.756 0.244 0.000
S42 Fracture of shoulder and upper arm
0.756 0.244 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
D10 Benign neoplasm of mouth and pharynx
0.754 0.246 0.000
M25.54 Pain in joint (Hand)
0.754 0.246 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.753 0.247 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.753 0.247 0.000
Y85 Sequelae of transport accidents
0.753 0.247 0.000
E27 Other disorders of adrenal gland
0.752 0.248 0.000
D36 Benign neoplasm of other and unspecified sites
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.749 0.250 0.000
Y52 Agents primarily affecting the cardiovascular system
0.749 0.251 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.749 0.251 0.000
D24 Benign neoplasm of breast
0.746 0.254 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.746 0.254 0.000
E10-E14 Diabetes mellitus
0.746 0.254 0.000
M87.9 Osteonecrosis, unspecified
0.745 0.255 0.000
S32.0 Fracture of lumbar vertebra
0.743 0.257 0.000
M75.0 Adhesive capsulitis of shoulder
0.743 0.257 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.741 0.259 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.740 0.260 0.000
M85 Other disorders of bone density and structure
0.740 0.260 0.000
M22.8 Other disorders of patella
0.740 0.260 0.000
M15-M19 Arthrosis
0.739 0.261 0.000
V40-V49 Car occupant injured in transport accident
0.737 0.263 0.000
S00.5 Superficial injury of lip and oral cavity
0.736 0.264 0.000
N17-N19 Renal failure
0.736 0.264 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.735 0.265 0.000
N34 Urethritis and urethral syndrome
0.734 0.266 0.000
X50-X57 Overexertion, travel and privation
0.733 0.267 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.732 0.268 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.731 0.269 0.000
L85 Other epidermal thickening
0.730 0.270 0.000
S00.1 Contusion of eyelid and periocular area
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.270 0.000
M81 Osteoporosis without pathological fracture
0.729 0.271 0.000
M34.8 Other forms of systemic sclerosis
0.729 0.271 0.000
M35.0 Sicca syndrome [Sjogren]
0.729 0.271 0.000
E00-E07 Disorders of thyroid gland
0.729 0.271 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.727 0.273 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.726 0.274 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
T88.4 Failed or difficult intubation
0.724 0.276 0.000
T87 Complications peculiar to reattachment and amputation
0.722 0.278 0.000
S00.7 Multiple superficial injuries of head
0.722 0.278 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.721 0.279 0.000
M22.4 Chondromalacia patellae
0.719 0.281 0.000
N76 Other inflammation of vagina and vulva
0.719 0.281 0.000
G62 Other polyneuropathies
0.719 0.281 0.000
M25.53 Pain in joint (Forearm)
0.717 0.282 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.717 0.282 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.716 0.284 0.000
M86 Osteomyelitis
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.715 0.285 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.715 0.285 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
M24.0 Loose body in joint
0.714 0.286 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.714 0.286 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.713 0.287 0.000
M79.0 Rheumatism, unspecified
0.713 0.287 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.713 0.287 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.713 0.287 0.000
L94 Other localised connective tissue disorders
0.713 0.287 0.000
L87 Transepidermal elimination disorders
0.713 0.287 0.000
L88 Pyoderma gangrenosum
0.713 0.287 0.000
L86 Keratoderma in diseases classified elsewhere
0.713 0.287 0.000
L80 Vitiligo
0.713 0.287 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.713 0.287 0.000
M79.70 Fibromyalgia (Multiple sites)
0.713 0.287 0.000
M25.9 Joint disorder, unspecified
0.712 0.288 0.000
M25.2 Flail joint
0.712 0.288 0.000
M25.1 Fistula of joint
0.712 0.288 0.000
M25.0 Haemarthrosis
0.712 0.288 0.000
Y89 Sequelae of other external causes
0.712 0.288 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.712 0.288 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.711 0.289 0.000
M23.9 Internal derangement of knee, unspecified
0.710 0.290 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.710 0.290 0.000
M23.5 Chronic instability of knee
0.710 0.290 0.000
M23.0 Cystic meniscus
0.710 0.290 0.000
Y42.7 Androgens and anabolic congeners
0.710 0.290 0.000
M25.58 Pain in joint (Other)
0.710 0.290 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.709 0.291 0.000
C67.2 Lateral wall of bladder
0.708 0.292 0.000
E28.2 Polycystic ovarian syndrome
0.707 0.293 0.000
S14 Injury of nerves and spinal cord at neck level
0.706 0.294 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.296 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.296 0.000
L60 Nail disorders
0.702 0.297 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.702 0.298 0.000
G90-G99 Other disorders of the nervous system
0.701 0.299 0.000
D11 Benign neoplasm of major salivary glands
0.701 0.299 0.000
M51.2 Other specified intervertebral disk displacement
0.700 0.300 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.700 0.300 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.700 0.300 0.000
M35.8 Other specified systemic involvement of connective tissue
0.700 0.300 0.000
M35.7 Hypermobility syndrome
0.700 0.300 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.700 0.300 0.000
M35.5 Multifocal fibrosclerosis
0.700 0.300 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.700 0.300 0.000
M35.2 Behcet's disease
0.700 0.300 0.000
M35.1 Other overlap syndromes
0.700 0.300 0.000
G25 Other extrapyramidal and movement disorders
0.700 0.300 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.699 0.300 0.000
S37 Injury of urinary and pelvic organs
0.699 0.300 0.000
S36 Injury of intra-abdominal organs
0.699 0.300 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.699 0.300 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.699 0.300 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.699 0.300 0.000
S31 Open wound of abdomen, lower back and pelvis
0.699 0.300 0.000
S08 Traumatic amputation of part of head
0.699 0.301 0.000
S07 Crushing injury of head
0.699 0.301 0.000
S04 Injury of cranial nerves
0.699 0.301 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
M34.1 CR(E)ST syndrome
0.698 0.302 0.000
Y40.3 Macrolides
0.697 0.303 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.697 0.303 0.000
N71 Inflammatory disease of uterus, except cervix
0.697 0.303 0.000
T86 Failure and rejection of transplanted organs and tissues
0.696 0.304 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.696 0.304 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.695 0.305 0.000
M67.4 Ganglion
0.695 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
D05.0 Lobular carcinoma in situ
0.694 0.306 0.000
D31 Benign neoplasm of eye and adnexa
0.694 0.306 0.000
D30 Benign neoplasm of urinary organs
0.694 0.306 0.000
D29 Benign neoplasm of male genital organs
0.694 0.306 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.694 0.306 0.000
D19 Benign neoplasm of mesothelial tissue
0.694 0.306 0.000
D16 Benign neoplasm of bone and articular cartilage
0.694 0.306 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.694 0.306 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.306 0.000
V80-V89 Other land transport accidents
0.693 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
M23.4 Loose body in knee
0.693 0.307 0.000
N37 Urethral disorders in diseases classified elsewhere
0.693 0.307 0.000
N33 Bladder disorders in diseases classified elsewhere
0.693 0.307 0.000
N99-N99 Other disorders of the genitourinary system
0.693 0.307 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.693 0.307 0.000
T81.9 Unspecified complication of procedure
0.691 0.309 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.691 0.309 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.691 0.309 0.000
N35.0 Posttraumatic urethral stricture
0.691 0.309 0.000
M21.0 Valgus deformity, not elsewhere classified
0.690 0.310 0.000
D12.1 Appendix
0.689 0.310 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.689 0.311 0.000
S12 Fracture of neck
0.689 0.311 0.000
S01.3 Open wound of ear
0.689 0.311 0.000
H61 Other disorders of external ear
0.687 0.313 0.000
D26 Other benign neoplasms of uterus
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.686 0.314 0.000
M76 Enthesopathies of lower limb, excluding foot
0.686 0.314 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.686 0.314 0.000
W20-W49 Exposure to inanimate mechanical forces
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.685 0.315 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.685 0.315 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.685 0.315 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.685 0.315 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
T36 Poisoning by systemic antibiotics
0.685 0.315 0.000
T91 Sequelae of injuries of neck and trunk
0.684 0.316 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.683 0.317 0.000
Chapter I Certain infectious and parasitic diseases
0.682 0.318 0.000
D22.5 Melanocytic naevi of trunk
0.681 0.319 0.000
M53 Other dorsopathies, not elsewhere classified
0.679 0.320 0.000
S48 Traumatic amputation of shoulder and upper arm
0.679 0.321 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.679 0.321 0.000
S44 Injury of nerves at shoulder and upper arm level
0.679 0.321 0.000
S41 Open wound of shoulder and upper arm
0.679 0.321 0.000
S47 Crushing injury of shoulder and upper arm
0.679 0.321 0.000
E23 Hypofunction and other disorders of pituitary gland
0.679 0.321 0.000
N36.3 Prolapsed urethral mucosa
0.679 0.321 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
M25.56 Pain in joint (Lower leg)
0.679 0.321 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.679 0.321 0.000
E22 Hyperfunction of pituitary gland
0.678 0.322 0.000
M71 Other bursopathies
0.678 0.322 0.000
D05.1 Intraductal carcinoma in situ
0.678 0.322 0.000
E03 Other hypothyroidism
0.677 0.323 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.677 0.323 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.676 0.324 0.000
S80 Superficial injury of lower leg
0.676 0.324 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.676 0.324 0.000
M50.0 Cervical disk disorder with myelopathy
0.674 0.326 0.000
M88 Paget's disease of bone [osteitis deformans]
0.673 0.327 0.000
H66 Suppurative and unspecified otitis media
0.672 0.328 0.000
S05.8 Other injuries of eye and orbit
0.672 0.328 0.000
N20.0 Calculus of kidney
0.671 0.329 0.000
M79.5 Residual foreign body in soft tissue
0.670 0.330 0.000
S00.4 Superficial injury of ear
0.670 0.330 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.670 0.330 0.000
N70 Salpingitis and oophoritis
0.669 0.331 0.000
S32.4 Fracture of acetabulum
0.668 0.332 0.000
C15-C26 Malignant neoplasms of digestive organs
0.668 0.332 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.668 0.332 0.000
M79.9 Soft tissue disorder, unspecified
0.668 0.332 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.668 0.332 0.000
M79.3 Panniculitis, unspecified
0.668 0.332 0.000
M87.2 Osteonecrosis due to previous trauma
0.667 0.333 0.000
V20-V29 Motorcycle rider injured in transport accident
0.667 0.333 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.666 0.333 0.000
M66 Spontaneous rupture of synovium and tendon
0.666 0.333 0.000
T98 Sequelae of other and unspecified effects of external causes
0.665 0.335 0.000
T95 Sequelae of burns, corrosions and frostbite
0.665 0.335 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.665 0.335 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.665 0.335 0.000
M75.3 Calcific tendinitis of shoulder
0.665 0.335 0.000
T66-T78 Other and unspecified effects of external causes
0.665 0.335 0.000
L91 Hypertrophic disorders of skin
0.665 0.335 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.664 0.336 0.000
M25.4 Effusion of joint
0.664 0.336 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.663 0.337 0.000
D22.9 Melanocytic naevi, unspecified
0.662 0.337 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.662 0.338 0.000
M22.1 Recurrent subluxation of patella
0.662 0.338 0.000
M22.9 Disorder of patella, unspecified
0.662 0.338 0.000
M22.3 Other derangements of patella
0.662 0.338 0.000
M22.0 Recurrent dislocation of patella
0.662 0.338 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.662 0.338 0.000
M54.1 Radiculopathy
0.662 0.338 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.662 0.338 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.662 0.338 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.662 0.338 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.661 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y48 Anaesthetics and therapeutic gases
0.660 0.340 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.660 0.340 0.000
S02.2 Fracture of nasal bones
0.660 0.340 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.660 0.340 0.000
L92.0 Granuloma annulare
0.659 0.341 0.000
S00.3 Superficial injury of nose
0.658 0.341 0.000
C66 Malignant neoplasm of ureter
0.658 0.341 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.658 0.342 0.000
H69 Other disorders of Eustachian tube
0.657 0.342 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.657 0.343 0.000
M54.2 Cervicalgia
0.656 0.344 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.656 0.344 0.000
M90 Osteopathies in diseases classified elsewhere
0.655 0.345 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.655 0.345 0.000
M31.9 Necrotising vasculopathy, unspecified
0.654 0.346 0.000
M31.8 Other specified necrotising vasculopathies
0.654 0.346 0.000
M31.7 Microscopic polyangiitis
0.654 0.346 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.654 0.346 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.654 0.346 0.000
M31.2 Lethal midline granuloma
0.654 0.346 0.000
M31.1 Thrombotic microangiopathy
0.654 0.346 0.000
M31.0 Hypersensitivity angiitis
0.654 0.346 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.654 0.346 0.000
N10-N16 Renal tubulo-interstitial diseases
0.654 0.346 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.653 0.347 0.000
T90 Sequelae of injuries of head
0.653 0.347 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.653 0.347 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.653 0.347 0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis
0.653 0.347 0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)
0.653 0.347 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.653 0.347 0.000
N30 Cystitis
0.653 0.347 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.651 0.349 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.349 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.651 0.349 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.650 0.350 0.000
M79.10 Myalgia (Multiple sites)
0.650 0.350 0.000
M40-M43 Deforming dorsopathies
0.649 0.350 0.000
W00-W19 Falls
0.649 0.350 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.649 0.350 0.000
S06 Intracranial injury
0.648 0.352 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.648 0.352 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.647 0.353 0.000
D05.7 Other carcinoma in situ of breast
0.646 0.354 0.000
M89 Other disorders of bone
0.646 0.354 0.000
L52 Erythema nodosum
0.646 0.354 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.646 0.354 0.000
T92.1 Sequelae of fracture of arm
0.645 0.355 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.644 0.356 0.000
M34.0 Progressive systemic sclerosis
0.644 0.356 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.644 0.356 0.000
G23 Other degenerative diseases of basal ganglia
0.644 0.356 0.000
G21 Secondary Parkinsonism
0.644 0.356 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.644 0.356 0.000
G22 Parkinsonism in diseases classified elsewhere
0.644 0.356 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.644 0.356 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.644 0.356 0.000
M23.37 Other meniscus derangements-Capsular lig
0.643 0.357 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.643 0.357 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.643 0.357 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.643 0.357 0.000
M80 Osteoporosis with pathological fracture
0.643 0.357 0.000
N25-N29 Other disorders of kidney and ureter
0.643 0.357 0.000
S01.5 Open wound of lip and oral cavity
0.642 0.358 0.000
M79.16 Myalgia (Lower leg)
0.642 0.358 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.642 0.358 0.000
M85.8 Other specified disorders of bone density and structure
0.642 0.358 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.640 0.360 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.640 0.360 0.000
S02.8 Fractures of other skull and facial bones
0.640 0.360 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.640 0.360 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.640 0.360 0.000
G62.9 Polyneuropathy, unspecified
0.639 0.361 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.639 0.361 0.000
D32.0 Cerebral meninges
0.638 0.362 0.000
M79.8 Other specified soft tissue disorders
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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