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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs186478
log Bayes Factor = 1.388
Chromosome 1   position 49,177,150  (GRCh37) Explore rs186478 on Ensembl!
Variant rs186478 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.958 0.042 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.944 0.056 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.938 0.062 0.000
R07 Pain in throat and chest
0.932 0.068 0.000
Chapter II Neoplasms
0.926 0.074 0.000
R07.4 Chest pain, unspecified
0.918 0.082 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.908 0.092 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.862 0.138 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.847 0.153 0.000
R07.3 Other chest pain
0.846 0.154 0.000
Chapter IX Diseases of the circulatory system
0.831 0.169 0.000
Chapter X Diseases of the respiratory system
0.823 0.177 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.818 0.182 0.000
Chapter XI Diseases of the digestive system
0.816 0.184 0.000
Chapter VIII Diseases of the ear and mastoid process
0.813 0.187 0.000
R06 Abnormalities of breathing
0.810 0.190 0.000
I20-I25 Ischaemic heart diseases
0.800 0.200 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.795 0.205 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.794 0.206 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.793 0.207 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.793 0.207 0.000
Chapter V Mental and behavioural disorders
0.779 0.221 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.766 0.234 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.761 0.239 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.760 0.240 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.756 0.244 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.750 0.250 0.000
R04 Haemorrhage from respiratory passages
0.749 0.251 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.749 0.251 0.000
C79 Secondary malignant neoplasm of other sites
0.747 0.253 0.000
I20 Angina pectoris
0.741 0.259 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.738 0.262 0.000
K70-K77 Diseases of liver
0.737 0.263 0.000
I25 Chronic ischaemic heart disease
0.736 0.264 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.730 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
C15-C26 Malignant neoplasms of digestive organs
0.717 0.283 0.000
Chapter VI Diseases of the nervous system
0.715 0.285 0.000
C50-C50 Malignant neoplasm of breast
0.711 0.289 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.710 0.290 0.000
C64-C68 Malignant neoplasms of urinary tract
0.709 0.291 0.000
H65-H75 Diseases of middle ear and mastoid
0.708 0.292 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.706 0.294 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.706 0.294 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.706 0.294 0.000
R01 Cardiac murmurs and other cardiac sounds
0.703 0.297 0.000
R19.4 Change in bowel habit
0.702 0.298 0.000
R07.0 Pain in throat
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
R02 Gangrene, not elsewhere classified
0.695 0.305 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.695 0.305 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.690 0.310 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.690 0.310 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.689 0.311 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.688 0.312 0.000
R07.1 Chest pain on breathing
0.687 0.313 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.687 0.313 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.687 0.313 0.000
I60-I69 Cerebrovascular diseases
0.685 0.315 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.684 0.316 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.683 0.317 0.000
Chapter XXI Factors influencing health status and contact with health services
0.681 0.319 0.000
W00-W19 Falls
0.680 0.320 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.679 0.321 0.000
W20-W49 Exposure to inanimate mechanical forces
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.323 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.677 0.323 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.672 0.328 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.670 0.330 0.000
J20-J22 Other acute lower respiratory infections
0.668 0.331 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.666 0.334 0.000
Y83.8 Other surgical procedures
0.666 0.334 0.000
S60-S69 Injuries to the wrist and hand
0.665 0.335 0.000
Chapter VII Diseases of the eye and adnexa
0.664 0.336 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.663 0.337 0.000
R06.5 Mouth breathing
0.663 0.337 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.662 0.338 0.000
X50-X57 Overexertion, travel and privation
0.661 0.338 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.660 0.339 0.000
X10-X19 Contact with heat and hot substances
0.659 0.341 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.659 0.341 0.000
X20-X29 Contact with venomous animals and plants
0.659 0.341 0.000
S20-S29 Injuries to the thorax
0.659 0.341 0.000
V20-V29 Motorcycle rider injured in transport accident
0.657 0.343 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.657 0.343 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.344 0.000
D00-D09 In situ neoplasms
0.655 0.344 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.655 0.345 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.655 0.345 0.000
X00-X09 Exposure to smoke, fire and flames
0.655 0.345 0.000
Y10-Y34 Event of undetermined intent
0.655 0.345 0.000
V90-V94 Water transport accidents
0.655 0.345 0.000
V98-V99 Other and unspecified transport accidents
0.655 0.345 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
X30-X39 Exposure to forces of nature
0.654 0.346 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.652 0.347 0.000
X85-X99 Assault
0.652 0.347 0.000
W65-W74 Accidental drowning and submersion
0.652 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.652 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.652 0.348 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.651 0.349 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.651 0.349 0.000
T33-T35 Frostbite
0.651 0.349 0.000
T81 Complications of procedures, not elsewhere classified
0.651 0.349 0.000
V80-V89 Other land transport accidents
0.650 0.350 0.000
Y00-Y09 Assault
0.649 0.351 0.000
C34 Malignant neoplasm of bronchus and lung
0.648 0.352 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.648 0.352 0.000
T00-T07 Injuries involving multiple body regions
0.647 0.352 0.000
E65-E68 Obesity and other hyperalimentation
0.646 0.354 0.000
W75-W84 Other accidental threats to breathing
0.645 0.355 0.000
J40-J47 Chronic lower respiratory diseases
0.645 0.355 0.000
R07.2 Precordial pain
0.644 0.356 0.000
V40-V49 Car occupant injured in transport accident
0.643 0.356 0.000
C51-C58 Malignant neoplasms of female genital organs
0.643 0.357 0.000
V70-V79 Bus occupant injured in transport accident
0.641 0.359 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.641 0.359 0.000
I25.1 Atherosclerotic heart disease
0.640 0.360 0.000
E70-E90 Metabolic disorders
0.640 0.360 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.639 0.361 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.639 0.361 0.000
K65-K67 Diseases of peritoneum
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.636 0.364 0.000
Y83.6 Removal of other organ (partial) (total)
0.635 0.365 0.000
J60-J70 Lung diseases due to external agents
0.634 0.366 0.000
V01-V09 Pedestrian injured in transport accident
0.633 0.367 0.000
I20.0 Unstable angina
0.633 0.367 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.633 0.367 0.000
T79-T79 Certain early complications of trauma
0.632 0.367 0.000
X60-X84 Intentional self-harm
0.632 0.368 0.000
S10-S19 Injuries to the neck
0.631 0.368 0.000
I20.9 Angina pectoris, unspecified
0.632 0.368 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.631 0.369 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.629 0.371 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.628 0.372 0.000
R06.8 Other and unspecified abnormalities of breathing
0.628 0.372 0.000
S90-S99 Injuries to the ankle and foot
0.626 0.373 0.000
K76 Other diseases of liver
0.626 0.373 0.000
D80-D89 Certain disorders involving the immune mechanism
0.626 0.374 0.000
R47-R49 Symptoms and signs involving speech and voice
0.625 0.374 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.625 0.374 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.625 0.375 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.624 0.376 0.000
R06.0 Dyspnoea
0.623 0.377 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.622 0.378 0.000
K35-K38 Diseases of appendix
0.622 0.378 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.619 0.381 0.000
Y43 Primarily systemic agents
0.619 0.381 0.000
J90-J94 Other diseases of pleura
0.618 0.382 0.000
K55-K64 Other diseases of intestines
0.615 0.385 0.000
C80 Malignant neoplasm without specification of site
0.614 0.386 0.000
H60-H62 Diseases of external ear
0.613 0.387 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.610 0.390 0.000
D60-D64 Aplastic and other anaemias
0.610 0.390 0.000
R30-R39 Symptoms and signs involving the urinary system
0.609 0.391 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.609 0.391 0.000
R05 Cough
0.607 0.392 0.000
J30-J39 Other diseases of upper respiratory tract
0.607 0.393 0.000
R13 Dysphagia
0.606 0.394 0.000
S80-S89 Injuries to the knee and lower leg
0.605 0.395 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.605 0.395 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.604 0.395 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.602 0.398 0.000
S40-S49 Injuries to the shoulder and upper arm
0.601 0.398 0.000
R20 Disturbances of skin sensation
0.601 0.399 0.000
T87 Complications peculiar to reattachment and amputation
0.600 0.400 0.000
R06.2 Wheezing
0.598 0.401 0.000
I00-I02 Acute rheumatic fever
0.597 0.403 0.000
R18 Ascites
0.596 0.404 0.000
Y40 Systemic antibiotics
0.595 0.405 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.595 0.405 0.000
Y83.9 Surgical procedure, unspecified
0.595 0.405 0.000
R04.2 Haemoptysis
0.593 0.407 0.000
T86 Failure and rejection of transplanted organs and tissues
0.593 0.407 0.000
R17 Unspecified jaundice
0.591 0.409 0.000
S50-S59 Injuries to the elbow and forearm
0.591 0.409 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.590 0.409 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.590 0.410 0.000
Y52 Agents primarily affecting the cardiovascular system
0.590 0.410 0.000
R06.1 Stridor
0.590 0.410 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.590 0.410 0.000
R06.6 Hiccough
0.589 0.411 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.589 0.411 0.000
G40-G47 Episodic and paroxysmal disorders
0.588 0.411 0.000
D55-D59 Haemolytic anaemias
0.587 0.413 0.000
Y44 Agents primarily affecting blood constituents
0.586 0.414 0.000
C60-C63 Malignant neoplasms of male genital organs
0.586 0.414 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.585 0.415 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.585 0.415 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.585 0.415 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.585 0.415 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.584 0.416 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.583 0.417 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.583 0.417 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.582 0.418 0.000
I05-I09 Chronic rheumatic heart diseases
0.581 0.419 0.000
R06.7 Sneezing
0.581 0.419 0.000
R06.3 Periodic breathing
0.581 0.419 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.581 0.419 0.000
Y83.0 Surgical operation with transplant of whole organ
0.581 0.419 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.580 0.419 0.000
J95-J99 Other diseases of the respiratory system
0.580 0.420 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.580 0.420 0.000
D50-D53 Nutritional anaemias
0.579 0.420 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.579 0.421 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.579 0.421 0.000
Y83.5 Amputation of limb(s)
0.578 0.422 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.577 0.423 0.000
D10-D36 Benign neoplasms
0.577 0.423 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.577 0.423 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.577 0.423 0.000
Y48 Anaesthetics and therapeutic gases
0.577 0.423 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.576 0.424 0.000
I23 Certain current complications following acute myocardial infarction
0.576 0.424 0.000
H90-H95 Other disorders of ear
0.576 0.424 0.000
Y83.3 Surgical operation with formation of external stoma
0.576 0.424 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.575 0.425 0.000
J00-J06 Acute upper respiratory infections
0.574 0.425 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.573 0.426 0.001
K70 Alcoholic liver disease
0.574 0.426 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.573 0.426 0.000
D45 Polycythaemia vera
0.573 0.426 0.000
R15 Faecal incontinence
0.573 0.427 0.000
K74 Fibrosis and cirrhosis of liver
0.573 0.427 0.000
Y57 Other and unspecified drugs and medicaments
0.573 0.427 0.000
T36 Poisoning by systemic antibiotics
0.573 0.427 0.000
C77.3 Axillary and upper limb lymph nodes
0.573 0.427 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.572 0.427 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.572 0.427 0.000
S72 Fracture of femur
0.572 0.428 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.572 0.428 0.000
Y59 Other and unspecified vaccines and biological substances
0.572 0.428 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.572 0.428 0.000
I20.8 Other forms of angina pectoris
0.571 0.429 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.571 0.429 0.000
Y58 Bacterial vaccines
0.571 0.429 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.570 0.429 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.570 0.430 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.570 0.430 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.570 0.430 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.569 0.431 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.569 0.431 0.000
F99-F99 Unspecified mental disorder
0.569 0.431 0.000
Q60-Q64 Congenital malformations of the urinary system
0.569 0.431 0.000
S00-S09 Injuries to the head
0.568 0.432 0.000
C78.0 Secondary malignant neoplasm of lung
0.566 0.434 0.000
F60-F69 Disorders of adult personality and behaviour
0.566 0.434 0.000
H65 Nonsuppurative otitis media
0.565 0.435 0.000
J09-J18 Influenza and pneumonia
0.563 0.437 0.000
D46 Myelodysplastic syndromes
0.563 0.437 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.562 0.437 0.000
H80-H83 Diseases of inner ear
0.562 0.438 0.000
C18 Malignant neoplasm of colon
0.562 0.438 0.000
R04.0 Epistaxis
0.561 0.439 0.000
E66 Obesity
0.561 0.439 0.000
F70-F79 Mental retardation
0.560 0.440 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.559 0.441 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.559 0.441 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.558 0.441 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.558 0.442 0.000
K40-K46 Hernia
0.558 0.442 0.000
Q50-Q56 Congenital malformations of genital organs
0.557 0.443 0.000
C50 Malignant neoplasm of breast
0.557 0.443 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.557 0.443 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.557 0.443 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.556 0.443 0.000
I21 Acute myocardial infarction
0.556 0.444 0.000
R27 Other lack of coordination
0.556 0.444 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.555 0.445 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.555 0.445 0.000
R06.4 Hyperventilation
0.555 0.445 0.000
Q80-Q89 Other congenital malformations
0.555 0.445 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.555 0.445 0.000
E40-E46 Malnutrition
0.554 0.446 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.553 0.447 0.000
G90-G99 Other disorders of the nervous system
0.553 0.447 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.552 0.447 0.000
I24 Other acute ischaemic heart diseases
0.552 0.448 0.000
J22 Unspecified acute lower respiratory infection
0.552 0.448 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.552 0.448 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.552 0.448 0.000
C37 Malignant neoplasm of thymus
0.551 0.449 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.551 0.449 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.551 0.449 0.000
I25.2 Old myocardial infarction
0.551 0.449 0.000
C33 Malignant neoplasm of trachea
0.550 0.450 0.000
C31 Malignant neoplasm of accessory sinuses
0.550 0.450 0.000
C92 Myeloid leukaemia
0.550 0.450 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.549 0.450 0.000
C79.2 Secondary malignant neoplasm of skin
0.549 0.451 0.000
C32 Malignant neoplasm of larynx
0.549 0.451 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.549 0.451 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.548 0.452 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.548 0.452 0.000
F30-F39 Mood [affective] disorders
0.548 0.452 0.000
F80-F89 Disorders of psychological development
0.547 0.452 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.547 0.453 0.000
C77.2 Intra-abdominal lymph nodes
0.547 0.453 0.000
K72 Hepatic failure, not elsewhere classified
0.546 0.453 0.000
I20.1 Angina pectoris with documented spasm
0.546 0.454 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.546 0.454 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.545 0.455 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.545 0.455 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.544 0.456 0.000
R12 Heartburn
0.544 0.456 0.000
C78.7 Secondary malignant neoplasm of liver
0.543 0.457 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.543 0.457 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.543 0.457 0.000
Q35-Q37 Cleft lip and cleft palate
0.543 0.457 0.000
I25.5 Ischaemic cardiomyopathy
0.543 0.457 0.000
D69 Purpura and other haemorrhagic conditions
0.542 0.457 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.542 0.458 0.000
R19.5 Other fecal abnormalities
0.542 0.458 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.542 0.458 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.542 0.458 0.000
R23 Other skin changes
0.542 0.458 0.000
Q00-Q07 Congenital malformations of the nervous system
0.542 0.458 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.542 0.458 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.541 0.459 0.000
C25 Malignant neoplasm of pancreas
0.541 0.459 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.541 0.459 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.540 0.459 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.540 0.460 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.540 0.460 0.000
W19 Unspecified fall
0.539 0.460 0.000
R21 Rash and other nonspecific skin eruption
0.539 0.461 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.539 0.461 0.000
H71 Cholesteatoma of middle ear
0.538 0.462 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.538 0.462 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.538 0.462 0.000
R04.1 Haemorrhage from throat
0.538 0.462 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.537 0.462 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.537 0.463 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.536 0.464 0.000
T39.1 4-Aminophenol derivatives
0.536 0.464 0.000
K73 Chronic hepatitis, not elsewhere classified
0.536 0.464 0.000
J47 Bronchiectasis
0.535 0.465 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.535 0.465 0.000
S70 Superficial injury of hip and thigh
0.535 0.465 0.000
K75 Other inflammatory liver diseases
0.534 0.465 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.534 0.466 0.000
I22 Subsequent myocardial infarction
0.534 0.466 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.534 0.466 0.000
I74 Arterial embolism and thrombosis
0.534 0.466 0.000
G70-G73 Diseases of myoneural junction and muscle
0.533 0.467 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.532 0.468 0.000
H74 Other disorders of middle ear and mastoid
0.532 0.468 0.000
I25.4 Coronary artery aneurysm
0.531 0.468 0.000
R19.6 Halitosis
0.531 0.469 0.000
K71 Toxic liver disease
0.531 0.469 0.000
O80-O84 Delivery
0.530 0.469 0.000
H72 Perforation of tympanic membrane
0.530 0.469 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.530 0.470 0.000
R19.2 Visible peristalsis
0.530 0.470 0.000
Chapter XIV Diseases of the genitourinary system
0.530 0.470 0.000
R26 Abnormalities of gait and mobility
0.529 0.471 0.000
R19.3 Abdominal rigidity
0.529 0.471 0.000
R19.1 Abnormal bowel sounds
0.529 0.471 0.000
K77 Liver disorders in diseases classified elsewhere
0.529 0.471 0.000
I25.6 Silent myocardial ischaemia
0.528 0.471 0.000
C91 Lymphoid leukaemia
0.528 0.471 0.000
H73 Other disorders of tympanic membrane
0.528 0.472 0.000
I67 Other cerebrovascular diseases
0.528 0.472 0.000
R01.1 Cardiac murmur, unspecified
0.528 0.472 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.527 0.473 0.000
C77.1 Intrathoracic lymph nodes
0.527 0.473 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.527 0.473 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.526 0.473 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.527 0.473 0.000
C95 Leukaemia of unspecified cell type
0.527 0.473 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.526 0.474 0.000
C93 Monocytic leukaemia
0.525 0.475 0.000
C21 Malignant neoplasm of anus and anal canal
0.525 0.475 0.000
T51 Toxic effect of alcohol
0.525 0.475 0.000
C86 Other specified types of T/NK-cell lymphoma
0.525 0.475 0.000
C94 Other leukaemias of specified cell type
0.524 0.475 0.000
I73 Other peripheral vascular diseases
0.525 0.475 0.000
C81 Hodgkin's disease
0.524 0.476 0.000
C17 Malignant neoplasm of small intestine
0.524 0.476 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.524 0.476 0.000
R25 Abnormal involuntary movements
0.524 0.476 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.524 0.476 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.523 0.477 0.000
S71 Open wound of hip and thigh
0.523 0.477 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.522 0.478 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.521 0.479 0.000
C79.6 Secondary malignant neoplasm of ovary
0.521 0.479 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.521 0.479 0.000
G30-G32 Other degenerative diseases of the nervous system
0.521 0.479 0.000
R09.0 Asphyxia
0.521 0.479 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.520 0.479 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.520 0.480 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.520 0.480 0.000
H66 Suppurative and unspecified otitis media
0.520 0.480 0.000
E86 Volume depletion
0.519 0.481 0.000
C71 Malignant neoplasm of brain
0.519 0.481 0.000
I77 Other disorders of arteries and arterioles
0.519 0.481 0.000
C77.8 Lymph nodes of multiple regions
0.519 0.481 0.000
S75 Injury of blood vessels at hip and thigh level
0.518 0.482 0.000
E50-E64 Other nutritional deficiencies
0.518 0.482 0.000
S74 Injury of nerves at hip and thigh level
0.518 0.482 0.000
S78 Traumatic amputation of hip and thigh
0.518 0.482 0.000
S77 Crushing injury of hip and thigh
0.518 0.482 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.518 0.482 0.000
C77.0 Lymph nodes of head, face and neck
0.518 0.482 0.000
K29 Gastritis and duodenitis
0.518 0.482 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.517 0.483 0.000
K50-K52 Noninfective enteritis and colitis
0.517 0.483 0.000
C09 Malignant neoplasm of tonsil
0.517 0.483 0.000
H69 Other disorders of Eustachian tube
0.516 0.484 0.000
C77.9 Lymph node, unspecified
0.516 0.484 0.000
O00-O08 Pregnancy with abortive outcome
0.516 0.484 0.000
C67 Malignant neoplasm of bladder
0.516 0.484 0.000
C34.1 Upper lobe, bronchus or lung
0.516 0.484 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.515 0.484 0.000
O60-O75 Complications of labour and delivery
0.515 0.485 0.000
C01 Malignant neoplasm of base of tongue
0.515 0.485 0.000
H30-H36 Disorders of choroid and retina
0.515 0.485 0.000
I25.3 Aneurysm of heart
0.515 0.485 0.000
R09.2 Respiratory arrest
0.515 0.485 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.515 0.485 0.000
S61 Open wound of wrist and hand
0.514 0.486 0.000
C66 Malignant neoplasm of ureter
0.514 0.486 0.000
C34.9 Bronchus or lung, unspecified
0.513 0.487 0.000
R09.3 Abnormal sputum
0.513 0.487 0.000
R14 Flatulence and related conditions
0.513 0.487 0.000
H70 Mastoiditis and related conditions
0.513 0.487 0.000
C65 Malignant neoplasm of renal pelvis
0.513 0.487 0.000
G47 Sleep disorders
0.513 0.487 0.000
S79 Other and unspecified injuries of hip and thigh
0.512 0.488 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.512 0.488 0.000
R94 Abnormal results of function studies
0.512 0.488 0.000
E66.9 Obesity, unspecified
0.512 0.488 0.000
R01.0 Benign and innocent cardiac murmurs
0.511 0.488 0.000
T78 Adverse effects, not elsewhere classified
0.511 0.488 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.511 0.488 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.511 0.489 0.000
C07 Malignant neoplasm of parotid gland
0.511 0.489 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.511 0.489 0.000
T92 Sequelae of injuries of upper limb
0.511 0.489 0.000
C45 Mesothelioma
0.510 0.490 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.510 0.490 0.000
S32 Fracture of lumbar spine and pelvis
0.510 0.490 0.000
C05 Malignant neoplasm of palate
0.509 0.490 0.000
T82.1 Mechanical complication of cardiac electronic device
0.509 0.491 0.000
E00-E07 Disorders of thyroid gland
0.509 0.491 0.000
C10 Malignant neoplasm of oropharynx
0.509 0.491 0.000
I60 Subarachnoid haemorrhage
0.509 0.491 0.000
C04 Malignant neoplasm of floor of mouth
0.509 0.491 0.000
H68 Eustachian salpingitis and obstruction
0.508 0.491 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.508 0.491 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.508 0.491 0.000
C12 Malignant neoplasm of pyriform sinus
0.508 0.492 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.508 0.492 0.000
I62 Other nontraumatic intracranial haemorrhage
0.508 0.492 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.508 0.492 0.000
C00 Malignant neoplasm of lip
0.508 0.492 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.508 0.492 0.000
H67 Otitis media in diseases classified elsewhere
0.508 0.492 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.508 0.492 0.000
C03 Malignant neoplasm of gum
0.508 0.492 0.000
C11 Malignant neoplasm of nasopharynx
0.508 0.492 0.000
C13 Malignant neoplasm of hypopharynx
0.507 0.492 0.000
C69 Malignant neoplasm of eye and adnexa
0.507 0.493 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.507 0.493 0.000
Chapter I Certain infectious and parasitic diseases
0.506 0.493 0.000
T91 Sequelae of injuries of neck and trunk
0.506 0.494 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.506 0.494 0.000
W22 Striking against or struck by other objects
0.506 0.494 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.505 0.495 0.000
T18 Foreign body in alimentary tract
0.505 0.495 0.000
R01.2 Other cardiac sounds
0.504 0.496 0.000
I70 Atherosclerosis
0.504 0.496 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.504 0.496 0.000
K59 Other functional intestinal disorders
0.503 0.496 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.503 0.497 0.000
K90-K93 Other diseases of the digestive system
0.502 0.498 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.501 0.499 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.501 0.499 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.501 0.499 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.501 0.499 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.500 0.499 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.500 0.499 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.500 0.500 0.000
K57 Diverticular disease of intestine
0.500 0.500 0.000
W29 Contact with other powered hand tools and household machinery
0.499 0.501 0.000
R09.1 Pleurisy
0.499 0.501 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.499 0.501 0.000
C88 Malignant immunoproliferative diseases
0.499 0.501 0.000
C70 Malignant neoplasm of meninges
0.499 0.501 0.000
W10 Fall on and from stairs and steps
0.499 0.501 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.498 0.502 0.000
I72 Other aneurysm
0.498 0.502 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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