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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2834812
log Bayes Factor = 1.53993
Chromosome 21   position 36,533,662  (GRCh37) Explore rs2834812 on Ensembl!
Variant rs2834812 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.964 0.036 0.000
Chapter II Neoplasms
0.962 0.038 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.962 0.038 0.000
# Top node
0.962 0.038 0.000
D10-D36 Benign neoplasms
0.957 0.043 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.957 0.043 0.000
S00-S09 Injuries to the head
0.948 0.052 0.000
Chapter V Mental and behavioural disorders
0.948 0.052 0.000
C15-C26 Malignant neoplasms of digestive organs
0.945 0.055 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.941 0.059 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.931 0.069 0.000
C20 Malignant neoplasm of rectum
0.925 0.075 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.922 0.078 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.915 0.085 0.000
D12.3 Transverse colon
0.914 0.086 0.000
D12.5 Sigmoid colon
0.912 0.088 0.000
S00 Superficial injury of head
0.910 0.090 0.000
D12.4 Descending colon
0.907 0.093 0.000
C25 Malignant neoplasm of pancreas
0.889 0.111 0.000
D12.6 Colon, unspecified
0.887 0.113 0.000
T91 Sequelae of injuries of neck and trunk
0.887 0.113 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.884 0.116 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.883 0.117 0.000
D12.0 Caecum
0.872 0.128 0.000
S00.9 Superficial injury of head, part unspecified
0.869 0.131 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.868 0.132 0.000
Chapter VI Diseases of the nervous system
0.865 0.135 0.000
F99-F99 Unspecified mental disorder
0.858 0.142 0.000
T92 Sequelae of injuries of upper limb
0.839 0.161 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.838 0.162 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.835 0.165 0.000
S50-S59 Injuries to the elbow and forearm
0.835 0.165 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.834 0.166 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.833 0.167 0.000
C25.9 Pancreas, unspecified
0.832 0.168 0.000
O36 Maternal care for other known or suspected foetal problems
0.832 0.168 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.831 0.169 0.000
D34 Benign neoplasm of thyroid gland
0.827 0.173 0.000
D12.2 Ascending colon
0.819 0.181 0.000
O60-O75 Complications of labour and delivery
0.819 0.181 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.814 0.186 0.000
Chapter XX External causes of morbidity and mortality
0.799 0.201 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.798 0.202 0.000
F10.0 Acute intoxication
0.797 0.203 0.000
F99 Mental disorder, not otherwise specified
0.794 0.206 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.793 0.207 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.792 0.208 0.000
S06 Intracranial injury
0.792 0.208 0.000
S00.1 Contusion of eyelid and periocular area
0.791 0.209 0.000
C91 Lymphoid leukaemia
0.790 0.210 0.000
T91.3 Sequelae of injury of spinal cord
0.787 0.213 0.000
D23 Other benign neoplasms of skin
0.783 0.217 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.782 0.218 0.000
S05 Injury of eye and orbit
0.781 0.219 0.000
T79-T79 Certain early complications of trauma
0.777 0.223 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.772 0.228 0.000
Chapter I Certain infectious and parasitic diseases
0.771 0.229 0.000
O80-O84 Delivery
0.763 0.237 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.763 0.237 0.000
T17 Foreign body in respiratory tract
0.762 0.238 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.757 0.243 0.000
F00 Dementia in Alzheimer's disease
0.753 0.247 0.000
O00-O08 Pregnancy with abortive outcome
0.753 0.247 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.750 0.250 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.748 0.252 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.748 0.252 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.748 0.252 0.000
C92 Myeloid leukaemia
0.745 0.255 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.743 0.257 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.741 0.259 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.738 0.262 0.000
D23.7 Skin of lower limb, including hip
0.737 0.263 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.736 0.264 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.734 0.266 0.000
Chapter VIII Diseases of the ear and mastoid process
0.729 0.271 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.729 0.271 0.000
D36 Benign neoplasm of other and unspecified sites
0.728 0.272 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.725 0.275 0.000
C01 Malignant neoplasm of base of tongue
0.724 0.276 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.723 0.277 0.000
G70-G73 Diseases of myoneural junction and muscle
0.723 0.277 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.723 0.277 0.000
T00-T07 Injuries involving multiple body regions
0.723 0.277 0.000
S09 Other and unspecified injuries of head
0.722 0.278 0.000
C85.1 B-cell lymphoma, unspecified
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.717 0.283 0.000
D25 Leiomyoma of uterus
0.716 0.284 0.000
S52 Fracture of forearm
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
C25.0 Head of pancreas
0.715 0.285 0.000
G93 Other disorders of brain
0.714 0.286 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.713 0.287 0.000
F03 Unspecified dementia
0.713 0.287 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.713 0.287 0.000
T43.2 Other and unspecified antidepressants
0.713 0.287 0.000
T17.2 Foreign body in pharynx
0.711 0.289 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.710 0.289 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.709 0.290 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.709 0.291 0.000
O43 Placental disorders
0.707 0.293 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.706 0.294 0.000
G30-G32 Other degenerative diseases of the nervous system
0.701 0.299 0.000
F10.1 Harmful use
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.302 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.696 0.304 0.000
O44 Placenta praevia
0.696 0.304 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.696 0.304 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.695 0.305 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.693 0.307 0.000
T33-T35 Frostbite
0.691 0.309 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.691 0.309 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.691 0.309 0.000
T42.4 Benzodiazepines
0.690 0.310 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.690 0.310 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.690 0.310 0.000
D12.9 Anus and anal canal
0.690 0.310 0.000
D12.1 Appendix
0.690 0.310 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.690 0.310 0.000
S02 Fracture of skull and facial bones
0.689 0.311 0.000
O48 Prolonged pregnancy
0.689 0.311 0.000
O36.5 Maternal care for poor foetal growth
0.689 0.311 0.000
C91.1 Chronic lymphocytic leukaemia
0.688 0.312 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.688 0.312 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.686 0.314 0.000
D31 Benign neoplasm of eye and adnexa
0.686 0.314 0.000
D30 Benign neoplasm of urinary organs
0.686 0.314 0.000
D29 Benign neoplasm of male genital organs
0.686 0.314 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.686 0.314 0.000
D19 Benign neoplasm of mesothelial tissue
0.686 0.314 0.000
D16 Benign neoplasm of bone and articular cartilage
0.686 0.314 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.686 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.686 0.314 0.000
O72 Postpartum haemorrhage
0.686 0.314 0.000
C21 Malignant neoplasm of anus and anal canal
0.685 0.315 0.000
S06.5 Traumatic subdural haemorrhage
0.685 0.315 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.679 0.321 0.000
S07 Crushing injury of head
0.679 0.321 0.000
S04 Injury of cranial nerves
0.679 0.321 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.679 0.321 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.679 0.321 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.679 0.321 0.000
S60-S69 Injuries to the wrist and hand
0.679 0.321 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.678 0.322 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.678 0.322 0.000
B35-B49 Mycoses
0.677 0.323 0.000
C17 Malignant neoplasm of small intestine
0.677 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.677 0.323 0.000
D32 Benign neoplasm of meninges
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.675 0.325 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.675 0.325 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.675 0.325 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.675 0.325 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.675 0.325 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.675 0.325 0.000
T36 Poisoning by systemic antibiotics
0.675 0.325 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.673 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.326 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.673 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.673 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
S00.3 Superficial injury of nose
0.671 0.329 0.000
O16 Unspecified maternal hypertension
0.671 0.329 0.000
O61 Failed induction of labour
0.671 0.329 0.000
O30 Multiple gestation
0.669 0.331 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.667 0.332 0.000
C95 Leukaemia of unspecified cell type
0.667 0.332 0.000
C94 Other leukaemias of specified cell type
0.667 0.332 0.000
C93 Monocytic leukaemia
0.667 0.332 0.000
C88 Malignant immunoproliferative diseases
0.667 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.667 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.667 0.332 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.666 0.334 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.664 0.336 0.000
D37.5 Rectum
0.662 0.338 0.000
T43.9 Psychotropic drug, unspecified
0.661 0.339 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
T43.6 Psychostimulants with abuse potential
0.661 0.339 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.661 0.339 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.661 0.339 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.660 0.339 0.000
S01 Open wound of head
0.660 0.340 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.659 0.341 0.000
O73 Retained placenta and membranes, without haemorrhage
0.659 0.341 0.000
O00 Ectopic pregnancy
0.657 0.343 0.000
O45 Premature separation of placenta [abruptio placentae]
0.656 0.344 0.000
O33 Maternal care for known or suspected disproportion
0.656 0.344 0.000
O31 Complications specific to multiple gestation
0.656 0.344 0.000
O40 Polyhydramnios
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.655 0.345 0.000
S00.5 Superficial injury of lip and oral cavity
0.652 0.348 0.000
S00.4 Superficial injury of ear
0.652 0.348 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.652 0.348 0.000
C71 Malignant neoplasm of brain
0.652 0.348 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.652 0.348 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.651 0.348 0.000
F60-F69 Disorders of adult personality and behaviour
0.651 0.349 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.651 0.349 0.000
D48.1 Connective and other soft tissue
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.650 0.350 0.000
F30-F39 Mood [affective] disorders
0.650 0.350 0.000
C81 Hodgkin's disease
0.649 0.351 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.649 0.351 0.000
S52.5 Fracture of lower end of radius
0.648 0.352 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.648 0.352 0.000
O62 Abnormalities of forces of labour
0.647 0.353 0.000
O20 Haemorrhage in early pregnancy
0.646 0.354 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.646 0.354 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.645 0.355 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.644 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.641 0.359 0.000
T92.1 Sequelae of fracture of arm
0.641 0.359 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.640 0.359 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.640 0.359 0.000
C16 Malignant neoplasm of stomach
0.640 0.360 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.639 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.639 0.361 0.000
S00.8 Superficial injury of other parts of head
0.639 0.361 0.000
C25.8 Overlapping lesion of pancreas
0.637 0.362 0.000
C25.7 Other parts of pancreas
0.637 0.362 0.000
C25.4 Endocrine pancreas
0.637 0.362 0.000
C25.3 Pancreatic duct
0.637 0.362 0.000
C25.2 Tail of pancreas
0.637 0.362 0.000
C25.1 Body of pancreas
0.637 0.362 0.000
D27 Benign neoplasm of ovary
0.637 0.363 0.000
B15-B19 Viral hepatitis
0.637 0.363 0.000
G93.6 Cerebral oedema
0.637 0.363 0.000
S05.1 Contusion of eyeball and orbital tissues
0.637 0.363 0.000
D80-D89 Certain disorders involving the immune mechanism
0.636 0.364 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.636 0.364 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.636 0.364 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.636 0.364 0.000
T91.1 Sequelae of fracture of spine
0.636 0.364 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.636 0.364 0.000
S00.7 Multiple superficial injuries of head
0.634 0.366 0.000
S51 Open wound of forearm
0.633 0.366 0.000
G96 Other disorders of central nervous system
0.633 0.367 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.633 0.367 0.000
F02 Dementia in other diseases classified elsewhere
0.633 0.367 0.000
F09 Unspecified organic or symptomatic mental disorder
0.633 0.367 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.633 0.367 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.633 0.367 0.000
D24 Benign neoplasm of breast
0.631 0.369 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.631 0.369 0.000
T93 Sequelae of injuries of lower limb
0.630 0.370 0.000
W00-W19 Falls
0.629 0.371 0.000
G93.4 Encephalopathy, unspecified
0.627 0.373 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.627 0.373 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.627 0.373 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.626 0.374 0.000
D26 Other benign neoplasms of uterus
0.625 0.374 0.000
O36.8 Maternal care for other specified foetal problems
0.625 0.375 0.000
O36.6 Maternal care for excessive foetal growth
0.625 0.375 0.000
O41 Other disorders of amniotic fluid and membranes
0.624 0.376 0.000
D12.7 Rectosigmoid junction
0.623 0.377 0.000
O28 Abnormal findings on antenatal screening of mother
0.623 0.377 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.622 0.378 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.622 0.378 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.622 0.378 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.622 0.378 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.622 0.378 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.622 0.378 0.000
F11 Mental and behavioural disorders due to use of opioids
0.622 0.378 0.000
G70 Myasthenia gravis and other myoneural disorders
0.622 0.378 0.000
O36.9 Maternal care for foetal problem, unspecified
0.621 0.379 0.000
S90-S99 Injuries to the ankle and foot
0.620 0.380 0.000
S50 Superficial injury of forearm
0.619 0.381 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.619 0.381 0.000
G83 Other paralytic syndromes
0.617 0.383 0.000
O66 Other obstructed labour
0.616 0.384 0.000
C90.2 Plasmacytoma, extramedullary
0.616 0.384 0.000
F01 Vascular dementia
0.614 0.386 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.614 0.386 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.614 0.386 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.613 0.387 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.613 0.387 0.000
G82 Paraplegia and tetraplegia
0.612 0.388 0.000
O24 Diabetes mellitus in pregnancy
0.612 0.388 0.000
X60-X84 Intentional self-harm
0.611 0.389 0.000
O23 Infections of genito-urinary tract in pregnancy
0.611 0.389 0.000
W50-W64 Exposure to animate mechanical forces
0.608 0.392 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.608 0.392 0.000
V80-V89 Other land transport accidents
0.606 0.394 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.605 0.395 0.000
D69 Purpura and other haemorrhagic conditions
0.605 0.395 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.605 0.395 0.000
Q80-Q89 Other congenital malformations
0.604 0.396 0.000
D25.2 Subserosal leiomyoma of uterus
0.603 0.396 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.603 0.397 0.000
D23.5 Skin of trunk
0.602 0.398 0.000
Q60-Q64 Congenital malformations of the urinary system
0.602 0.398 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.601 0.398 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.601 0.398 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.601 0.398 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.601 0.398 0.000
T92.0 Sequelae of open wound of upper limb
0.601 0.398 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.601 0.399 0.000
Q35-Q37 Cleft lip and cleft palate
0.601 0.399 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.601 0.399 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.601 0.399 0.000
S52.50 Fracture of lower end of radius (closed)
0.600 0.400 0.000
G62 Other polyneuropathies
0.599 0.400 0.000
C64-C68 Malignant neoplasms of urinary tract
0.599 0.400 0.000
O80 Single spontaneous delivery
0.599 0.401 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.598 0.401 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.598 0.401 0.000
O34.6 Maternal care for abnormality of vagina
0.598 0.401 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.598 0.401 0.000
O34.4 Maternal care for other abnormalities of cervix
0.598 0.401 0.000
O34.3 Maternal care for cervical incompetence
0.598 0.401 0.000
O34.1 Maternal care for tumour of corpus uteri
0.598 0.401 0.000
O34.0 Maternal care for congenital malformation of uterus
0.598 0.401 0.000
S59 Other and unspecified injuries of forearm
0.598 0.401 0.000
S58 Traumatic amputation of forearm
0.598 0.401 0.000
S57 Crushing injury of forearm
0.598 0.401 0.000
S56 Injury of muscle and tendon at forearm level
0.598 0.401 0.000
S55 Injury of blood vessels at forearm level
0.598 0.401 0.000
S54 Injury of nerves at forearm level
0.598 0.401 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.598 0.401 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.598 0.402 0.000
C13 Malignant neoplasm of hypopharynx
0.598 0.402 0.000
C11 Malignant neoplasm of nasopharynx
0.598 0.402 0.000
C10 Malignant neoplasm of oropharynx
0.598 0.402 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.598 0.402 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.598 0.402 0.000
C05 Malignant neoplasm of palate
0.598 0.402 0.000
C04 Malignant neoplasm of floor of mouth
0.598 0.402 0.000
C03 Malignant neoplasm of gum
0.598 0.402 0.000
C00 Malignant neoplasm of lip
0.598 0.402 0.000
C12 Malignant neoplasm of pyriform sinus
0.598 0.402 0.000
C07 Malignant neoplasm of parotid gland
0.598 0.402 0.000
D46 Myelodysplastic syndromes
0.598 0.402 0.000
V40-V49 Car occupant injured in transport accident
0.597 0.402 0.000
T19 Foreign body in genito-urinary tract
0.597 0.403 0.000
T15 Foreign body on external eye
0.597 0.403 0.000
T16 Foreign body in ear
0.597 0.403 0.000
X20-X29 Contact with venomous animals and plants
0.597 0.403 0.000
S05.8 Other injuries of eye and orbit
0.597 0.403 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.596 0.404 0.000
O36.4 Maternal care for intra-uterine death
0.596 0.404 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.596 0.404 0.000
O36.2 Maternal care for hydrops foetalis
0.596 0.404 0.000
O36.1 Maternal care for other isoimmunisation
0.596 0.404 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.596 0.404 0.000
O15 Eclampsia
0.596 0.404 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.596 0.404 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.596 0.404 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.595 0.405 0.000
T66-T78 Other and unspecified effects of external causes
0.595 0.405 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.592 0.408 0.000
B65-B83 Helminthiases
0.592 0.408 0.000
S80-S89 Injuries to the knee and lower leg
0.591 0.409 0.000
O21 Excessive vomiting in pregnancy
0.591 0.409 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.590 0.410 0.000
C24.1 Ampulla of Vater
0.590 0.410 0.000
D37.4 Colon
0.587 0.412 0.000
O74 Complications of anaesthesia during labour and delivery
0.587 0.413 0.000
O71 Other obstetric trauma
0.587 0.413 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.587 0.413 0.000
O60 Preterm delivery
0.587 0.413 0.000
S02.4 Fracture of malar and maxillary bones
0.587 0.413 0.000
F05.9 Delirium, unspecified
0.587 0.413 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.586 0.414 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.586 0.414 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.586 0.414 0.000
C90.0 Multiple myeloma
0.585 0.415 0.000
F06.7 Mild cognitive disorder
0.585 0.415 0.000
O46.9 Antepartum haemorrhage, unspecified
0.585 0.415 0.000
H80-H83 Diseases of inner ear
0.585 0.415 0.000
B37 Candidiasis
0.584 0.416 0.000
C92.0 Acute myeloid leukaemia
0.584 0.416 0.000
F10.9 Unspecified mental and behavioural disorder
0.584 0.416 0.000
F10.8 Other mental and behavioural disorders
0.584 0.416 0.000
F10.7 Residual and late-onset psychotic disorder
0.584 0.416 0.000
F10.6 Amnesic syndrome
0.584 0.416 0.000
F10.5 Psychotic disorder
0.584 0.416 0.000
F10.4 Withdrawal state with delirium
0.584 0.416 0.000
D25.9 Leiomyoma of uterus, unspecified
0.583 0.417 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.583 0.417 0.000
S40-S49 Injuries to the shoulder and upper arm
0.583 0.417 0.000
D37.7 Other digestive organs
0.582 0.417 0.000
S64 Injury of nerves at wrist and hand level
0.582 0.418 0.000
G60 Hereditary and idiopathic neuropathy
0.581 0.419 0.000
D23.4 Skin of scalp and neck
0.580 0.420 0.000
S06.8 Other intracranial injuries
0.580 0.420 0.000
G30 Alzheimer's disease
0.579 0.421 0.000
G90 Disorders of autonomic nervous system
0.579 0.421 0.000
G95 Other diseases of spinal cord
0.578 0.422 0.000
O63 Long labour
0.576 0.424 0.000
U51 Admission status on psychiatric patients
0.576 0.424 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.575 0.425 0.000
D11 Benign neoplasm of major salivary glands
0.574 0.426 0.000
T90.9 Sequelae of unspecified injury of head
0.574 0.426 0.000
Y52 Agents primarily affecting the cardiovascular system
0.574 0.426 0.000
H60-H62 Diseases of external ear
0.573 0.427 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.573 0.427 0.000
Y35-Y36 Legal intervention and operations of war
0.573 0.427 0.000
Y10-Y34 Event of undetermined intent
0.573 0.427 0.000
Y00-Y09 Assault
0.573 0.427 0.000
X85-X99 Assault
0.573 0.427 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.573 0.427 0.000
X50-X57 Overexertion, travel and privation
0.573 0.427 0.000
X30-X39 Exposure to forces of nature
0.573 0.427 0.000
X10-X19 Contact with heat and hot substances
0.573 0.427 0.000
X00-X09 Exposure to smoke, fire and flames
0.573 0.427 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.573 0.427 0.000
W75-W84 Other accidental threats to breathing
0.573 0.427 0.000
W65-W74 Accidental drowning and submersion
0.573 0.427 0.000
V98-V99 Other and unspecified transport accidents
0.573 0.427 0.000
V95-V97 Air and space transport accidents
0.573 0.427 0.000
V90-V94 Water transport accidents
0.573 0.427 0.000
V70-V79 Bus occupant injured in transport accident
0.573 0.427 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.573 0.427 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.573 0.427 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.573 0.427 0.000
V01-V09 Pedestrian injured in transport accident
0.573 0.427 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.573 0.427 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.573 0.427 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.572 0.428 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.572 0.428 0.000
C85.0 Lymphosarcoma
0.572 0.428 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.571 0.429 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.570 0.430 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.570 0.430 0.000
C83.0 Small cell (diffuse)
0.570 0.430 0.000
O81 Single delivery by forceps and vacuum extractor
0.569 0.431 0.000
C92.1 Chronic myeloid leukaemia
0.569 0.431 0.000
D48.0 Bone and articular cartilage
0.569 0.431 0.000
O29 Complications of anaesthesia during pregnancy
0.569 0.431 0.000
O22 Venous complications in pregnancy
0.569 0.431 0.000
O25 Malnutrition in pregnancy
0.569 0.431 0.000
A00-A09 Intestinal infectious diseases
0.569 0.431 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.568 0.432 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.568 0.432 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.568 0.432 0.000
T42.3 Barbiturates
0.568 0.432 0.000
T42.2 Succinimides and oxazolidinediones
0.568 0.432 0.000
T42.1 Iminostilbenes
0.568 0.432 0.000
T42.0 Hydantoin derivatives
0.568 0.432 0.000
S06.9 Intracranial injury, unspecified
0.568 0.432 0.000
S06.7 Intracranial injury with prolonged coma
0.568 0.432 0.000
S06.4 Epidural haemorrhage
0.568 0.432 0.000
S06.3 Focal brain injury
0.568 0.432 0.000
S06.2 Diffuse brain injury
0.568 0.432 0.000
S06.1 Traumatic cerebral oedema
0.568 0.432 0.000
S06.0 Concussion
0.568 0.432 0.000
C02.9 Tongue, unspecified
0.568 0.432 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.567 0.433 0.000
O00.1 Tubal pregnancy
0.567 0.433 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.567 0.433 0.000
D23.6 Skin of upper limb, including shoulder
0.566 0.433 0.000
C91.9 Lymphoid leukaemia, unspecified
0.566 0.434 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.566 0.434 0.000
C91.7 Other lymphoid leukaemia
0.566 0.434 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.566 0.434 0.000
C91.5 Adult T-cell leukaemia
0.566 0.434 0.000
C91.4 Hairy-cell leukaemia
0.566 0.434 0.000
C91.3 Prolymphocytic leukaemia
0.566 0.434 0.000
C91.2 Subacute lymphocytic leukaemia
0.566 0.434 0.000
C91.0 Acute lymphoblastic leukaemia
0.566 0.434 0.000
Q65 Congenital deformities of hip
0.566 0.434 0.000
O72.1 Other immediate postpartum haemorrhage
0.566 0.434 0.000
O61.0 Failed medical induction of labour
0.564 0.435 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.563 0.437 0.000
D55-D59 Haemolytic anaemias
0.562 0.438 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.561 0.439 0.000
D23.0 Skin of lip
0.561 0.439 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.561 0.439 0.000
C70 Malignant neoplasm of meninges
0.561 0.439 0.000
C69 Malignant neoplasm of eye and adnexa
0.561 0.439 0.000
S09.9 Unspecified injury of head
0.561 0.439 0.000
O82 Single delivery by Caesarean section
0.560 0.440 0.000
C60-C63 Malignant neoplasms of male genital organs
0.560 0.440 0.000
D00-D09 In situ neoplasms
0.560 0.440 0.000
O02 Other abnormal products of conception
0.560 0.440 0.000
S00.0 Superficial injury of scalp
0.560 0.440 0.000
S05.9 Injury of eye and orbit, part unspecified
0.560 0.440 0.000
S05.7 Avulsion of eye
0.560 0.440 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.560 0.440 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.560 0.440 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.560 0.440 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.560 0.440 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.560 0.440 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.560 0.440 0.000
D10 Benign neoplasm of mouth and pharynx
0.558 0.442 0.000
O43.8 Other placental disorders
0.558 0.442 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.557 0.443 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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