TreeWAS – Variant ID: rs549182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10.9 Without complications	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
E10.3 With ophthalmic complications	0.996	0.004
Chapter XI Diseases of the digestive system	0.990	0.010
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.985	0.015
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.985	0.015
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.976	0.024
M50-M54 Other dorsopathies	0.976	0.024
R91 Abnormal findings on diagnostic imaging of lung	0.975	0.025
R30-R39 Symptoms and signs involving the urinary system	0.971	0.029
R39 Other symptoms and signs involving the urinary system	0.967	0.033
Chapter II Neoplasms	0.967	0.033
M70-M79 Other soft tissue disorders	0.965	0.035
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.964	0.036
Chapter VII Diseases of the eye and adnexa	0.956	0.044
M54 Dorsalgia	0.955	0.045
E10.4 With neurological complications	0.955	0.045
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.954	0.046
S20-S29 Injuries to the thorax	0.945	0.055
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.945	0.055
K55-K64 Other diseases of intestines	0.945	0.055
K90-K93 Other diseases of the digestive system	0.945	0.055
Chapter V Mental and behavioural disorders	0.941	0.059
H30-H36 Disorders of choroid and retina	0.939	0.061
M54.5 Low back pain	0.935	0.065
E10.1 With ketoacidosis	0.931	0.069
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.930	0.070
M54.56 Low back pain (Lumbar region)	0.928	0.072
H36 Retinal disorders in diseases classified elsewhere	0.927	0.073
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.925	0.075
K90 Intestinal malabsorption	0.925	0.075
M75 Shoulder lesions	0.924	0.076
H36.0 Diabetic retinopathy	0.918	0.082
Chapter VI Diseases of the nervous system	0.918	0.082
K40-K46 Hernia	0.911	0.089
K90.0 Coeliac disease	0.911	0.089
D50-D53 Nutritional anaemias	0.909	0.091
S40-S49 Injuries to the shoulder and upper arm	0.908	0.092
S50-S59 Injuries to the elbow and forearm	0.905	0.095
D68 Other coagulation defects	0.901	0.099
M75.4 Impingement syndrome of shoulder	0.895	0.105
T36-T50 Poisoning by drugs, medicaments and biological substances	0.894	0.106
D37-D48 Neoplasms of uncertain or unknown behaviour	0.892	0.108
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.890	0.110
K62 Other diseases of anus and rectum	0.888	0.112
K62.1 Rectal polyp	0.887	0.113
G35-G37 Demyelinating diseases of the central nervous system	0.884	0.116
E16 Other disorders of pancreatic internal secretion	0.879	0.120
C15-C26 Malignant neoplasms of digestive organs	0.872	0.128
K44 Diaphragmatic hernia	0.872	0.128
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.872	0.128
F30-F39 Mood [affective] disorders	0.869	0.131
K55 Vascular disorders of intestine	0.868	0.132
M20-M25 Other joint disorders	0.867	0.133
C64-C68 Malignant neoplasms of urinary tract	0.866	0.134
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.863	0.137
M86-M90 Other osteopathies	0.859	0.141
S00-S09 Injuries to the head	0.859	0.141
G35 Multiple sclerosis	0.858	0.142
K35-K38 Diseases of appendix	0.855	0.145
D60-D64 Aplastic and other anaemias	0.849	0.151
T66-T78 Other and unspecified effects of external causes	0.848	0.152
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.844	0.156
E16.2 Hypoglycaemia, unspecified	0.844	0.156
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.843	0.157
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.842	0.158
D50 Iron deficiency anaemia	0.842	0.158
D69 Purpura and other haemorrhagic conditions	0.839	0.161
K55.2 Angiodysplasia of colon	0.831	0.169
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.828	0.172
G90-G99 Other disorders of the nervous system	0.828	0.172
S42 Fracture of shoulder and upper arm	0.828	0.172
E05 Thyrotoxicosis [hyperthyroidism]	0.827	0.173
C67 Malignant neoplasm of bladder	0.827	0.173
S32 Fracture of lumbar spine and pelvis	0.826	0.174
S22 Fracture of rib(s), sternum and thoracic spine	0.823	0.177
S20 Superficial injury of thorax	0.822	0.178
S52 Fracture of forearm	0.819	0.181
K41 Femoral hernia	0.819	0.181
K65-K67 Diseases of peritoneum	0.818	0.181
K63 Other diseases of intestine	0.818	0.182
S30 Superficial injury of abdomen, lower back and pelvis	0.818	0.182
K83 Other diseases of biliary tract	0.817	0.183
D00-D09 In situ neoplasms	0.815	0.185
T88 Other complications of surgical and medical care, not elsewhere classified	0.815	0.185
E10.5 With peripheral circulatory complications	0.809	0.191
E20-E35 Disorders of other endocrine glands	0.808	0.192
H46-H48 Disorders of optic nerve and visual pathways	0.805	0.195
C34 Malignant neoplasm of bronchus and lung	0.803	0.197
R21 Rash and other nonspecific skin eruption	0.797	0.203
Chapter XX External causes of morbidity and mortality	0.794	0.206
M23 Internal derangement of knee	0.790	0.210
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.788	0.211
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.787	0.213
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.783	0.217
K62.3 Rectal prolapse	0.782	0.218
M53 Other dorsopathies, not elsewhere classified	0.782	0.218
F31 Bipolar affective disorder	0.780	0.220
E65-E68 Obesity and other hyperalimentation	0.780	0.220
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.780	0.220
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.774	0.226
M25 Other joint disorders, not elsewhere classified	0.773	0.227
M65-M68 Disorders of synovium and tendon	0.772	0.228
M75.1 Rotator cuff syndrome	0.772	0.228
S80-S89 Injuries to the knee and lower leg	0.772	0.228
D50.8 Other iron deficiency anaemias	0.771	0.229
M80-M85 Disorders of bone density and structure	0.770	0.230
E07 Other disorders of thyroid	0.770	0.230
K83.1 Obstruction of bile duct	0.770	0.230
E14 Unspecified diabetes mellitus	0.769	0.231
K63.5 Polyp of colon	0.765	0.235
M45-M49 Spondylopathies	0.764	0.236
M77 Other enthesopathies	0.764	0.236
E13 Other specified diabetes mellitus	0.762	0.238
M54.4 Lumbago with sciatica	0.759	0.241
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.759	0.241
M51 Other intervertebral disk disorders	0.759	0.241
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.759	0.241
C67.9 Bladder, unspecified	0.757	0.243
D68.8 Other specified coagulation defects	0.756	0.244
M71 Other bursopathies	0.756	0.244
R34 Anuria and oliguria	0.756	0.244
H25-H28 Disorders of lens	0.755	0.245
T15-T19 Effects of foreign body entering through natural orifice	0.754	0.246
M91-M94 Chondropathies	0.754	0.246
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.753	0.247
T81 Complications of procedures, not elsewhere classified	0.753	0.247
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.753	0.247
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.752	0.247
S90-S99 Injuries to the ankle and foot	0.752	0.248
T83.0 Mechanical complication of urinary (indwelling) catheter	0.750	0.250
S27 Injury of other and unspecified intrathoracic organs	0.750	0.250
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.749	0.251
K56 Paralytic ileus and intestinal obstruction without hernia	0.749	0.251
D68.6 Other Thrombophilia	0.748	0.252
F30 Manic episode	0.747	0.253
T88.7 Unspecified adverse effect of drug or medicament	0.747	0.253
R23 Other skin changes	0.746	0.254
S01 Open wound of head	0.745	0.255
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.744	0.256
E11 Non-insulin-dependent diabetes mellitus	0.741	0.259
C23 Malignant neoplasm of gallbladder	0.741	0.259
T78 Adverse effects, not elsewhere classified	0.740	0.260
Chapter XXII Codes for special purposes	0.738	0.262
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.736	0.264
H34 Retinal vascular occlusions	0.736	0.264
T83.1 Mechanical complication of other urinary devices and implants	0.735	0.265
R39.1 Other difficulties with micturition	0.734	0.266
D68.0 Von Willebrand's disease	0.731	0.269
D64 Other anaemias	0.728	0.272
M79 Other soft tissue disorders, not elsewhere classified	0.726	0.274
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.726	0.274
F17 Mental and behavioural disorders due to use of tobacco	0.726	0.274
S06 Intracranial injury	0.725	0.275
M23.2 Derangement of meniscus due to old tear or injury	0.722	0.278
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.720	0.280
R32 Unspecified urinary incontinence	0.719	0.281
M54.1 Radiculopathy	0.717	0.283
K81 Cholecystitis	0.717	0.283
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
K65 Peritonitis	0.717	0.283
C34.9 Bronchus or lung, unspecified	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
M60-M63 Disorders of muscles	0.716	0.284
M00-M03 Infectious arthropathies	0.716	0.284
K42 Umbilical hernia	0.716	0.284
H33 Retinal detachments and breaks	0.714	0.286
K83.0 Cholangitis	0.712	0.288
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.710	0.290
E06 Thyroiditis	0.709	0.291
R30 Pain associated with micturition	0.709	0.291
S60-S69 Injuries to the wrist and hand	0.708	0.292
D69.3 Idiopathic thrombocytopenic purpura	0.708	0.292
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.708	0.292
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.708	0.292
R76 Other abnormal immunological findings in serum	0.707	0.292
G70-G73 Diseases of myoneural junction and muscle	0.707	0.293
K59 Other functional intestinal disorders	0.707	0.293
R95-R99 Ill-defined and unknown causes of mortality	0.707	0.293
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.706	0.294
D55-D59 Haemolytic anaemias	0.706	0.294
M89 Other disorders of bone	0.706	0.294
F40-F48 Neurotic, stress-related and somatoform disorders	0.706	0.294
G91 Hydrocephalus	0.706	0.294
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.705	0.294
M54.3 Sciatica	0.704	0.296
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.704	0.296
F60-F69 Disorders of adult personality and behaviour	0.704	0.296
M40-M43 Deforming dorsopathies	0.704	0.296
C24.0 Extrahepatic bile duct	0.703	0.297
S22.4 Multiple fractures of ribs	0.701	0.299
S50 Superficial injury of forearm	0.701	0.299
S42.0 Fracture of clavicle	0.700	0.300
R92 Abnormal findings on diagnostic imaging of breast	0.700	0.300
D68.9 Coagulation defect, unspecified	0.699	0.301
M75.2 Bicipital tendinitis	0.698	0.302
R36 Urethral discharge	0.696	0.304
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.696	0.304
S46 Injury of muscle and tendon at shoulder and upper arm level	0.695	0.304
S52.5 Fracture of lower end of radius	0.695	0.305
K38 Other diseases of appendix	0.695	0.305
R39.2 Extrarenal uraemia	0.694	0.306
R39.0 Extravasation of urine	0.694	0.306
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.693	0.306
C40-C41 Malignant neoplasms of bone and articular cartilage	0.693	0.306
R90 Abnormal findings on diagnostic imaging of central nervous system	0.693	0.307
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.693	0.307
C34.1 Upper lobe, bronchus or lung	0.693	0.307
M76 Enthesopathies of lower limb, excluding foot	0.692	0.308
M73 Soft tissue disorders in diseases classified elsewhere	0.692	0.308
D68.2 Hereditary deficiency of other clotting factors	0.692	0.308
S42.1 Fracture of scapula	0.691	0.309
D69.6 Thrombocytopenia, unspecified	0.691	0.309
S29 Other and unspecified injuries of thorax	0.690	0.310
M54.50 Low back pain (Multiple sites in spine)	0.689	0.310
M24 Other specific joint derangements	0.689	0.311
D03 Melanoma in situ	0.686	0.314
Q20-Q28 Congenital malformations of the circulatory system	0.686	0.314
T78.4 Allergy, unspecified	0.685	0.315
M54.8 Other dorsalgia	0.685	0.315
M54.6 Pain in thoracic spine	0.685	0.315
M54.0 Panniculitis affecting regions of neck and back	0.685	0.315
D52 Folate deficiency anaemia	0.685	0.315
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.684	0.316
D67 Hereditary factor IX deficiency	0.684	0.316
D66 Hereditary factor VIII deficiency	0.684	0.316
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.684	0.316
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.683	0.317
H55-H59 Other disorders of eye and adnexa	0.682	0.317
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.682	0.318
G99 Other disorders of nervous system in diseases classified elsewhere	0.681	0.319
G80-G83 Cerebral palsy and other paralytic syndromes	0.680	0.320
M75.0 Adhesive capsulitis of shoulder	0.680	0.320
E11.3 With ophthalmic complications	0.680	0.320
F17.1 Harmful use	0.680	0.320
T79-T79 Certain early complications of trauma	0.679	0.320
S01.0 Open wound of scalp	0.679	0.321
H26 Other cataract	0.679	0.321
M34 Systemic sclerosis	0.679	0.321
S20.3 Other superficial injuries of front wall of thorax	0.678	0.322
T81.3 Disruption of operation wound, not elsewhere classified	0.678	0.322
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.678	0.322
S26 Injury of heart	0.678	0.322
S25 Injury of blood vessels of thorax	0.678	0.322
S24 Injury of nerves and spinal cord at thorax level	0.678	0.322
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.678	0.322
S21 Open wound of thorax	0.678	0.322
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.678	0.322
S37 Injury of urinary and pelvic organs	0.678	0.322
S36 Injury of intra-abdominal organs	0.678	0.322
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.678	0.322
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.678	0.322
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.678	0.322
S31 Open wound of abdomen, lower back and pelvis	0.678	0.322
K64 Haemorrhoids and perianal venous thrombosis	0.677	0.322
K93 Disorders of other digestive organs in diseases classified elsewhere	0.677	0.322
D50.9 Iron deficiency anaemia, unspecified	0.676	0.324
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.675	0.324
M87 Osteonecrosis	0.675	0.325
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.674	0.325
F80-F89 Disorders of psychological development	0.674	0.325
F70-F79 Mental retardation	0.674	0.325
M70 Soft tissue disorders related to use, overuse and pressure	0.674	0.326
S52.6 Fracture of lower end of both ulna and radius	0.673	0.327
H32 Chorioretinal disorders in diseases classified elsewhere	0.673	0.327
H31 Other disorders of choroid	0.673	0.327
H30 Chorioretinal inflammation	0.673	0.327
C19 Malignant neoplasm of rectosigmoid junction	0.673	0.327
H40-H42 Glaucoma	0.671	0.329
D05 Carcinoma in situ of breast	0.671	0.329
M54.55 Low back pain (Thoracolumbar region)	0.671	0.329
M54.54 Low back pain-Thoracic	0.671	0.329
M54.53 Low back pain-Cervicothoracic	0.671	0.329
M54.52 Low back pain-Cervical	0.671	0.329
M54.51 Low back pain-Occipit-atl-axl	0.671	0.329
K37 Unspecified appendicitis	0.670	0.330
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.670	0.330
C26 Malignant neoplasm of other and ill-defined digestive organs	0.670	0.330
S30.2 Contusion of external genital organs	0.670	0.330
D51 Vitamin B12 deficiency anaemia	0.669	0.331
C18 Malignant neoplasm of colon	0.669	0.331
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.668	0.332
M65 Synovitis and tenosynovitis	0.668	0.332
S42.3 Fracture of shaft of humerus	0.667	0.333
E15 Nondiabetic hypoglycaemic coma	0.667	0.333
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.666	0.334
G30-G32 Other degenerative diseases of the nervous system	0.665	0.335
H36.8 Other retinal disorders in diseases classified elsewhere	0.664	0.335
D61 Other aplastic anaemias	0.664	0.336
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.664	0.336
T87 Complications peculiar to reattachment and amputation	0.663	0.337
T86 Failure and rejection of transplanted organs and tissues	0.663	0.337
T80 Complications following infusion, transfusion and therapeutic injection	0.663	0.337
K90.8 Other intestinal malabsorption	0.663	0.337
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.663	0.337
K90.3 Pancreatic steatorrhoea	0.663	0.337
K90.2 Blind loop syndrome, not elsewhere classified	0.663	0.337
K90.1 Tropical sprue	0.663	0.337
S30.1 Contusion of abdominal wall	0.662	0.338
M75.8 Other shoulder lesions	0.662	0.338
M75.9 Shoulder lesion, unspecified	0.662	0.338
K35 Acute appendicitis	0.662	0.338
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.662	0.338
S20.8 Superficial injuries of other and unspecified parts of thorax	0.661	0.339
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.661	0.339
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.660	0.339
Q60-Q64 Congenital malformations of the urinary system	0.660	0.339
F30.0 Hypomania	0.660	0.340
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.659	0.341
K90.9 Intestinal malabsorption, unspecified	0.658	0.342
D10-D36 Benign neoplasms	0.658	0.342
G00-G09 Inflammatory diseases of the central nervous system	0.658	0.342
M72 Fibroblastic disorders	0.658	0.342
C67.4 Posterior wall of bladder	0.658	0.342
F99-F99 Unspecified mental disorder	0.658	0.342
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.656	0.344
Q80-Q89 Other congenital malformations	0.655	0.345
C67.5 Bladder neck	0.655	0.345
H46 Optic neuritis	0.655	0.345
K63.3 Ulcer of intestine	0.654	0.346
K45 Other abdominal hernia	0.653	0.346
S32.0 Fracture of lumbar vertebra	0.653	0.347
Q50-Q56 Congenital malformations of genital organs	0.653	0.347
S32.7 Multiple fractures of lumbar spine and pelvis	0.652	0.348
D53 Other nutritional anaemias	0.652	0.348
G96 Other disorders of central nervous system	0.651	0.349
M23.0 Cystic meniscus	0.651	0.349
S48 Traumatic amputation of shoulder and upper arm	0.651	0.349
S45 Injury of blood vessels at shoulder and upper arm level	0.651	0.349
S44 Injury of nerves at shoulder and upper arm level	0.651	0.349
S41 Open wound of shoulder and upper arm	0.651	0.349
S40 Superficial injury of shoulder and upper arm	0.651	0.349
S47 Crushing injury of shoulder and upper arm	0.651	0.349
M54.2 Cervicalgia	0.651	0.349
S32.3 Fracture of ilium	0.651	0.349
R76.8 Other specified abnormal immunological findings in serum	0.651	0.349
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.650	0.350
M86 Osteomyelitis	0.649	0.351
S59 Other and unspecified injuries of forearm	0.649	0.351
S58 Traumatic amputation of forearm	0.649	0.351
S57 Crushing injury of forearm	0.649	0.351
S56 Injury of muscle and tendon at forearm level	0.649	0.351
S55 Injury of blood vessels at forearm level	0.649	0.351
S54 Injury of nerves at forearm level	0.649	0.351
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.649	0.351
S51 Open wound of forearm	0.649	0.351
M21 Other acquired deformities of limbs	0.648	0.351
S49 Other and unspecified injuries of shoulder and upper arm	0.648	0.352
D62 Acute posthaemorrhagic anaemia	0.648	0.352
D37.5 Rectum	0.648	0.352
H10-H13 Disorders of conjunctiva	0.648	0.352
Chapter I Certain infectious and parasitic diseases	0.648	0.352
C67.2 Lateral wall of bladder	0.647	0.353
M54.9 Dorsalgia, unspecified	0.647	0.353
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.647	0.353
D68.5 Primary Thrombophilia	0.646	0.354
D68.4 Acquired coagulation factor deficiency	0.646	0.354
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.646	0.354
D68.1 Hereditary factor XI deficiency	0.646	0.354
M47 Spondylosis	0.645	0.355
M22 Disorders of patella	0.645	0.355
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.644	0.356
W00-W19 Falls	0.644	0.356
T43.0 Tricyclic and tetracyclic antidepressants	0.643	0.357
F10 Mental and behavioural disorders due to use of alcohol	0.643	0.357
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.642	0.358
H47 Other disorders of optic [2nd] nerve and visual pathways	0.642	0.358
M54.59 Low back pain (Site unspecified)	0.641	0.359
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.641	0.359
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.641	0.359
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.641	0.359
T46 Poisoning by agents primarily affecting the cardiovascular system	0.641	0.359
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.641	0.359
T41 Poisoning by anaesthetics and therapeutic gases	0.641	0.359
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.641	0.359
T36 Poisoning by systemic antibiotics	0.641	0.359
D64.9 Anaemia, unspecified	0.641	0.359
S22.0 Fracture of thoracic vertebra	0.641	0.359
G37 Other demyelinating diseases of central nervous system	0.640	0.359
S02 Fracture of skull and facial bones	0.640	0.360
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.639	0.360
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.639	0.360
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.639	0.360
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.639	0.360
C43-C44 Melanoma and other malignant neoplasms of skin	0.639	0.361
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.639	0.361
C22.1 Intrahepatic bile duct carcinoma	0.639	0.361
E05.9 Thyrotoxicosis, unspecified	0.638	0.362
Q38-Q45 Other congenital malformations of the digestive system	0.638	0.362
K56.6 Other and unspecified intestinal obstruction	0.637	0.363
K62.2 Anal prolapse	0.637	0.363
K81.9 Cholecystitis, unspecified	0.637	0.363
K61 Abscess of anal and rectal regions	0.636	0.364
R31 Unspecified haematuria	0.636	0.364
R35 Polyuria	0.634	0.366
G36 Other acute disseminated demyelination	0.633	0.366
D32 Benign neoplasm of meninges	0.634	0.366
M23.8 Other internal derangements of knee	0.632	0.368
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.631	0.369
E16.9 Disorder of pancreatic internal secretion, unspecified	0.631	0.369
E16.8 Other specified disorders of pancreatic internal secretion	0.631	0.369
E16.4 Abnormal secretion of gastrin	0.631	0.369
E16.3 Increased secretion of glucagon	0.631	0.369
E16.1 Other hypoglycaemia	0.631	0.369
E16.0 Drug-induced hypoglycaemia without coma	0.631	0.369
V40-V49 Car occupant injured in transport accident	0.630	0.370
T43.3 Phenothiazine antipsychotics and neuroleptics	0.630	0.370
E34 Other endocrine disorders	0.628	0.372
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.627	0.373
S01.3 Open wound of ear	0.627	0.373
S42.4 Fracture of lower end of humerus	0.626	0.374
C34.2 Middle lobe, bronchus or lung	0.626	0.374
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.626	0.374
C21 Malignant neoplasm of anus and anal canal	0.625	0.375
C17 Malignant neoplasm of small intestine	0.625	0.375
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.625	0.375
K44.1 Diaphragmatic hernia with gangrene	0.625	0.375
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.625	0.375
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.625	0.375
C38 Malignant neoplasm of heart, mediastinum and pleura	0.625	0.375
C32 Malignant neoplasm of larynx	0.625	0.375
C31 Malignant neoplasm of accessory sinuses	0.625	0.375
C30 Malignant neoplasm of nasal cavity and middle ear	0.625	0.375
C37 Malignant neoplasm of thymus	0.625	0.375
C33 Malignant neoplasm of trachea	0.625	0.375
D41.4 Bladder	0.625	0.375
R72 Abnormality of white blood cells, not elsewhere classified	0.624	0.376
S52.1 Fracture of upper end of radius	0.624	0.376
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.623	0.377
F38 Other mood [affective] disorders	0.623	0.377
F34 Persistent mood [affective] disorders	0.623	0.377
F39 Unspecified mood [affective] disorder	0.623	0.377
E66 Obesity	0.623	0.377
K55.8 Other vascular disorders of intestine	0.623	0.377
K55.1 Chronic vascular disorders of intestine	0.623	0.377
T14 Injury of unspecified body region	0.623	0.377
M79.1 Myalgia	0.622	0.378
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.622	0.378
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.621	0.378
M33 Dermatopolymyositis	0.621	0.378
M32 Systemic lupus erythematosus	0.621	0.378
M30 Polyarteritis nodosa and related conditions	0.621	0.378
C68 Malignant neoplasm of other and unspecified urinary organs	0.621	0.379
C66 Malignant neoplasm of ureter	0.621	0.379
C65 Malignant neoplasm of renal pelvis	0.621	0.379
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.621	0.379
M25.5 Pain in joint	0.621	0.379
X20-X29 Contact with venomous animals and plants	0.620	0.380
F33 Recurrent depressive disorder	0.620	0.380
K63.1 Perforation of intestine (nontraumatic)	0.620	0.380
M25.8 Other specified joint disorders	0.619	0.380
M54.46 Lumbago with sciatica (Lumbar region)	0.619	0.381
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.618	0.381
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.618	0.381
Q35-Q37 Cleft lip and cleft palate	0.618	0.381
Q30-Q34 Congenital malformations of the respiratory system	0.618	0.381
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.618	0.381
Q00-Q07 Congenital malformations of the nervous system	0.618	0.381
S32.5 Fracture of pubis	0.618	0.382
R23.3 Spontaneous ecchymoses	0.618	0.382
S01.2 Open wound of nose	0.618	0.382
D09 Carcinoma in situ of other and unspecified sites	0.617	0.383
K83.8 Other specified diseases of biliary tract	0.617	0.383
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.616	0.384
M90 Osteopathies in diseases classified elsewhere	0.616	0.384
M88 Paget's disease of bone [osteitis deformans]	0.616	0.384
S08 Traumatic amputation of part of head	0.616	0.384
S07 Crushing injury of head	0.616	0.384
S05 Injury of eye and orbit	0.616	0.384
S04 Injury of cranial nerves	0.616	0.384
S03 Dislocation, sprain and strain of joints and ligaments of head	0.616	0.384

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations