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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56113960
log Bayes Factor = 17.1557
Chromosome 22   position 21,355,501  (GRCh37) Explore rs56113960 on Ensembl!
Variant rs56113960 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.993 0.007 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.984 0.016 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
R55 Syncope and collapse
0.982 0.018 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.977 0.023 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.972 0.028 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.971 0.029 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.970 0.030 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.968 0.032 0.000
C15-C26 Malignant neoplasms of digestive organs
0.964 0.036 0.000
J09-J18 Influenza and pneumonia
0.956 0.044 0.000
Chapter V Mental and behavioural disorders
0.953 0.047 0.000
I42 Cardiomyopathy
0.952 0.048 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.951 0.049 0.000
C79 Secondary malignant neoplasm of other sites
0.942 0.058 0.000
O26.8 Other specified pregnancy-related conditions
0.940 0.060 0.000
J40-J47 Chronic lower respiratory diseases
0.940 0.060 0.000
R69 Unknown and unspecified causes of morbidity
0.933 0.067 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.929 0.071 0.000
O60-O75 Complications of labour and delivery
0.929 0.071 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.926 0.074 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.924 0.076 0.000
J18 Pneumonia, organism unspecified
0.921 0.079 0.000
M05-M14 Inflammatory polyarthropathies
0.918 0.082 0.000
I60-I69 Cerebrovascular diseases
0.917 0.083 0.000
Z50 Care involving use of rehabilitation procedures
0.912 0.088 0.000
J18.1 Lobar pneumonia, unspecified
0.911 0.089 0.000
I73 Other peripheral vascular diseases
0.910 0.090 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.907 0.093 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.906 0.094 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.901 0.099 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.895 0.105 0.000
Z50.1 Other physical therapy
0.895 0.105 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.893 0.107 0.000
R54 Senility
0.892 0.108 0.000
C51-C58 Malignant neoplasms of female genital organs
0.892 0.108 0.000
I25.2 Old myocardial infarction
0.889 0.111 0.000
D60-D64 Aplastic and other anaemias
0.887 0.113 0.000
R59 Enlarged lymph nodes
0.887 0.113 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.884 0.116 0.000
I47 Paroxysmal tachycardia
0.882 0.118 0.000
Z39 Postpartum care and examination
0.880 0.120 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.879 0.121 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.877 0.123 0.000
Z36 Antenatal screening
0.873 0.127 0.000
C15 Malignant neoplasm of oesophagus
0.872 0.128 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.871 0.129 0.000
I42.0 Dilated cardiomyopathy
0.868 0.132 0.000
I77 Other disorders of arteries and arterioles
0.866 0.134 0.000
C78.0 Secondary malignant neoplasm of lung
0.865 0.135 0.000
I42.9 Cardiomyopathy, unspecified
0.859 0.141 0.000
O26.9 Pregnancy-related condition, unspecified
0.856 0.144 0.000
R51 Headache
0.856 0.144 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.855 0.145 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.854 0.146 0.000
J95-J99 Other diseases of the respiratory system
0.853 0.147 0.000
Z37 Outcome of delivery
0.853 0.147 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.852 0.148 0.000
F30-F39 Mood [affective] disorders
0.851 0.149 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.850 0.149 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.847 0.153 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.847 0.153 0.000
C18 Malignant neoplasm of colon
0.846 0.154 0.000
J44 Other chronic obstructive pulmonary disease
0.846 0.154 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.844 0.156 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.843 0.157 0.000
I25.1 Atherosclerotic heart disease
0.840 0.160 0.000
I46 Cardiac arrest
0.840 0.160 0.000
R73 Elevated blood glucose level
0.836 0.164 0.000
I74 Arterial embolism and thrombosis
0.835 0.165 0.000
Chapter I Certain infectious and parasitic diseases
0.834 0.166 0.000
I69 Sequelae of cerebrovascular disease
0.834 0.166 0.000
J43 Emphysema
0.833 0.167 0.000
R94 Abnormal results of function studies
0.833 0.167 0.000
Z33 Pregnant state, incidental
0.829 0.171 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.827 0.173 0.000
I27 Other pulmonary heart diseases
0.827 0.173 0.000
T39.1 4-Aminophenol derivatives
0.827 0.173 0.000
I34 Nonrheumatic mitral valve disorders
0.826 0.174 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.825 0.175 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.825 0.175 0.000
I73.0 Raynaud's syndrome
0.820 0.180 0.000
Z02 Examination and encounter for administrative purposes
0.820 0.180 0.000
Z13 Special screening examination for other diseases and disorders
0.820 0.180 0.000
I30 Acute pericarditis
0.819 0.181 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.814 0.186 0.000
R47-R49 Symptoms and signs involving speech and voice
0.814 0.186 0.000
Z39.0 Care and examination immediately after delivery
0.810 0.190 0.000
R52 Pain, not elsewhere classified
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.809 0.191 0.000
Z01.8 Other specified special examinations
0.808 0.192 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.807 0.193 0.000
I50 Heart failure
0.807 0.193 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.807 0.193 0.000
Z45 Adjustment and management of implanted device
0.806 0.194 0.000
M91-M94 Chondropathies
0.806 0.194 0.000
M72 Fibroblastic disorders
0.805 0.195 0.000
D00-D09 In situ neoplasms
0.803 0.197 0.000
T40.2 Other opioids
0.803 0.197 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.802 0.198 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.801 0.199 0.000
M13 Other arthritis
0.801 0.199 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.800 0.200 0.000
R59.1 Generalised enlarged lymph nodes
0.797 0.203 0.000
O21 Excessive vomiting in pregnancy
0.797 0.203 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.794 0.206 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.794 0.206 0.000
Z51 Other medical care
0.792 0.208 0.000
F60-F69 Disorders of adult personality and behaviour
0.791 0.209 0.000
I25.5 Ischaemic cardiomyopathy
0.791 0.209 0.000
M75 Shoulder lesions
0.791 0.209 0.000
C15.5 Lower third of oesophagus
0.789 0.211 0.000
Z37.0 Single live birth
0.788 0.212 0.000
O24 Diabetes mellitus in pregnancy
0.788 0.212 0.000
I73.9 Peripheral vascular disease, unspecified
0.787 0.213 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.787 0.213 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.786 0.214 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.786 0.214 0.000
J47 Bronchiectasis
0.785 0.215 0.000
I05-I09 Chronic rheumatic heart diseases
0.785 0.215 0.000
I47.1 Supraventricular tachycardia
0.783 0.217 0.000
M65-M68 Disorders of synovium and tendon
0.783 0.217 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.782 0.218 0.000
Z31 Procreative management
0.782 0.218 0.000
R94.5 Abnormal results of liver function studies
0.782 0.218 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
C78.2 Secondary malignant neoplasm of pleura
0.782 0.218 0.000
Chapter XX External causes of morbidity and mortality
0.781 0.219 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.781 0.219 0.000
R56 Convulsions, not elsewhere classified
0.780 0.220 0.000
C16 Malignant neoplasm of stomach
0.780 0.220 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.779 0.221 0.000
D69 Purpura and other haemorrhagic conditions
0.777 0.223 0.000
I25.3 Aneurysm of heart
0.777 0.223 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.775 0.225 0.000
O62 Abnormalities of forces of labour
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.771 0.229 0.000
M86-M90 Other osteopathies
0.771 0.229 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.769 0.231 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.769 0.231 0.000
D37.4 Colon
0.769 0.231 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.767 0.233 0.000
O32.1 Maternal care for breech presentation
0.767 0.233 0.000
I38 Endocarditis, valve unspecified
0.765 0.235 0.000
Z35 Supervision of high-risk pregnancy
0.764 0.236 0.000
R60 Oedema, not elsewhere classified
0.763 0.237 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.761 0.239 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.761 0.239 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.759 0.241 0.000
D75 Other diseases of blood and blood-forming organs
0.758 0.242 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.758 0.242 0.000
J43.9 Emphysema, unspecified
0.757 0.243 0.000
M12 Other specific arthropathies
0.756 0.244 0.000
I33 Acute and subacute endocarditis
0.755 0.245 0.000
O43 Placental disorders
0.755 0.245 0.000
I21 Acute myocardial infarction
0.755 0.245 0.000
J40 Bronchitis, not specified as acute or chronic
0.754 0.246 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.754 0.246 0.000
R79 Other abnormal findings of blood chemistry
0.752 0.248 0.000
O00-O08 Pregnancy with abortive outcome
0.752 0.248 0.000
J60-J70 Lung diseases due to external agents
0.751 0.249 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.751 0.249 0.000
Z34 Supervision of normal pregnancy
0.751 0.249 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
O41 Other disorders of amniotic fluid and membranes
0.749 0.251 0.000
I50.0 Congestive heart failure
0.747 0.253 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.747 0.253 0.000
J10 Influenza due to identified influenza virus
0.746 0.253 0.000
O42 Premature rupture of membranes
0.744 0.255 0.000
C71 Malignant neoplasm of brain
0.743 0.257 0.000
R59.9 Enlarged lymph nodes, unspecified
0.742 0.258 0.000
Chapter VI Diseases of the nervous system
0.742 0.258 0.000
Z02.8 Other examinations for administrative purposes
0.741 0.259 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
T40.4 Other synthetic narcotics
0.740 0.260 0.000
I74.5 Embolism and thrombosis of iliac artery
0.739 0.261 0.000
C34 Malignant neoplasm of bronchus and lung
0.738 0.262 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.737 0.262 0.000
M05 Seropositive rheumatoid arthritis
0.737 0.263 0.000
Z51.1 Chemotherapy session for neoplasm
0.737 0.263 0.000
R73.0 Abnormal glucose tolerance test
0.737 0.263 0.000
I51 Complications and ill-defined descriptions of heart disease
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.735 0.265 0.000
D68 Other coagulation defects
0.735 0.265 0.000
I67 Other cerebrovascular diseases
0.735 0.265 0.000
Z01.7 Laboratory examination
0.735 0.265 0.000
F31 Bipolar affective disorder
0.735 0.265 0.000
I77.6 Arteritis, unspecified
0.735 0.265 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.734 0.266 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.734 0.266 0.000
O70 Perineal laceration during delivery
0.733 0.267 0.000
R61 Hyperhidrosis
0.733 0.267 0.000
I44 Atrioventricular and left bundle-branch block
0.732 0.268 0.000
C79.6 Secondary malignant neoplasm of ovary
0.730 0.270 0.000
O71 Other obstetric trauma
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.271 0.000
D45 Polycythaemia vera
0.729 0.271 0.000
S80-S89 Injuries to the knee and lower leg
0.729 0.271 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.728 0.272 0.000
Z40 Prophylactic surgery
0.727 0.273 0.000
I49 Other cardiac arrhythmias
0.726 0.274 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.726 0.274 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
C54 Malignant neoplasm of corpus uteri
0.725 0.275 0.000
J98 Other respiratory disorders
0.725 0.275 0.000
Chapter VII Diseases of the eye and adnexa
0.725 0.275 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.724 0.276 0.000
C77.2 Intra-abdominal lymph nodes
0.723 0.276 0.000
C56 Malignant neoplasm of ovary
0.723 0.277 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.721 0.279 0.000
D48.1 Connective and other soft tissue
0.721 0.279 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.719 0.281 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.718 0.282 0.000
I46.0 Cardiac arrest with successful resuscitation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
M13.9 Arthritis, unspecified
0.717 0.283 0.000
O46.9 Antepartum haemorrhage, unspecified
0.717 0.283 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.716 0.284 0.000
C80 Malignant neoplasm without specification of site
0.716 0.284 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
R68 Other general symptoms and signs
0.715 0.285 0.000
D46 Myelodysplastic syndromes
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
O48 Prolonged pregnancy
0.713 0.287 0.000
C77.5 Intrapelvic lymph nodes
0.713 0.287 0.000
Z50.2 Alcohol rehabilitation
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.713 0.287 0.000
I70 Atherosclerosis
0.712 0.288 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
S00-S09 Injuries to the head
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.288 0.000
I48 Atrial fibrillation and flutter
0.711 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.288 0.000
I40 Acute myocarditis
0.711 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.288 0.000
I37 Pulmonary valve disorders
0.711 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.711 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.288 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.711 0.289 0.000
Z01.9 Special examination, unspecified
0.709 0.291 0.000
O72 Postpartum haemorrhage
0.708 0.291 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.708 0.292 0.000
I72 Other aneurysm
0.708 0.292 0.000
D80-D89 Certain disorders involving the immune mechanism
0.707 0.292 0.000
M75.1 Rotator cuff syndrome
0.706 0.294 0.000
O29 Complications of anaesthesia during pregnancy
0.706 0.294 0.000
O28 Abnormal findings on antenatal screening of mother
0.706 0.294 0.000
O23 Infections of genito-urinary tract in pregnancy
0.706 0.294 0.000
O22 Venous complications in pregnancy
0.706 0.294 0.000
O25 Malnutrition in pregnancy
0.706 0.294 0.000
C18.0 Caecum
0.705 0.295 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.705 0.295 0.000
Z38 Liveborn infants according to place of birth
0.705 0.295 0.000
Z32 Pregnancy examination and test
0.705 0.295 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S10-S19 Injuries to the neck
0.704 0.296 0.000
M79.0 Rheumatism, unspecified
0.704 0.296 0.000
O63 Long labour
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
I60 Subarachnoid haemorrhage
0.702 0.298 0.000
R49 Voice disturbances
0.702 0.298 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.701 0.299 0.000
R76 Other abnormal immunological findings in serum
0.700 0.300 0.000
O45 Premature separation of placenta [abruptio placentae]
0.700 0.300 0.000
O44 Placenta praevia
0.700 0.300 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.700 0.300 0.000
O33 Maternal care for known or suspected disproportion
0.700 0.300 0.000
O31 Complications specific to multiple gestation
0.700 0.300 0.000
O40 Polyhydramnios
0.700 0.300 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
D62 Acute posthaemorrhagic anaemia
0.700 0.300 0.000
I27.2 Other secondary pulmonary hypertension
0.700 0.300 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.699 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.699 0.301 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.699 0.301 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.699 0.301 0.000
T36 Poisoning by systemic antibiotics
0.699 0.301 0.000
I62 Other nontraumatic intracranial haemorrhage
0.698 0.302 0.000
C18.5 Splenic flexure
0.698 0.302 0.000
R74 Abnormal serum enzyme levels
0.697 0.303 0.000
D55-D59 Haemolytic anaemias
0.697 0.303 0.000
B35-B49 Mycoses
0.696 0.304 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.696 0.304 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.696 0.304 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.696 0.304 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.696 0.304 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.696 0.304 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.696 0.304 0.000
D64 Other anaemias
0.696 0.304 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.695 0.305 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.695 0.305 0.000
M06 Other rheumatoid arthritis
0.695 0.305 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.695 0.305 0.000
I30.9 Acute pericarditis, unspecified
0.694 0.306 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.694 0.306 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.694 0.306 0.000
O26.5 Maternal hypotension syndrome
0.694 0.306 0.000
O26.4 Herpes gestationis
0.694 0.306 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.694 0.306 0.000
O26.2 Pregnancy care of habitual aborter
0.694 0.306 0.000
O26.1 Low weight gain in pregnancy
0.694 0.306 0.000
O26.0 Excessive weight gain in pregnancy
0.694 0.306 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.694 0.306 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.693 0.307 0.000
I77.8 Other specified disorders of arteries and arterioles
0.692 0.308 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.692 0.308 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.691 0.309 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.691 0.309 0.000
C21 Malignant neoplasm of anus and anal canal
0.691 0.309 0.000
C17 Malignant neoplasm of small intestine
0.691 0.309 0.000
C23 Malignant neoplasm of gallbladder
0.691 0.309 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
C20 Malignant neoplasm of rectum
0.689 0.311 0.000
F03 Unspecified dementia
0.688 0.311 0.000
L40-L45 Papulosquamous disorders
0.688 0.311 0.000
I27.9 Pulmonary heart disease, unspecified
0.688 0.312 0.000
R73.9 Hyperglycaemia, unspecified
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.687 0.313 0.000
C64-C68 Malignant neoplasms of urinary tract
0.686 0.314 0.000
J00-J06 Acute upper respiratory infections
0.686 0.314 0.000
S50-S59 Injuries to the elbow and forearm
0.686 0.314 0.000
C90.2 Plasmacytoma, extramedullary
0.686 0.314 0.000
J17 Pneumonia in diseases classified elsewhere
0.686 0.314 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.686 0.314 0.000
J12 Viral pneumonia, not elsewhere classified
0.686 0.314 0.000
J11 Influenza, virus not identified
0.686 0.314 0.000
J14 Pneumonia due to Haemophilus influenzae
0.686 0.314 0.000
J09 Influenza due to certain identified influenza virus
0.686 0.314 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.683 0.317 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
F70-F79 Mental retardation
0.683 0.317 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.683 0.317 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.683 0.317 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.683 0.317 0.000
Z50.8 Care involving use of rehabilitation procedures
0.683 0.317 0.000
T39.0 Salicylates
0.682 0.317 0.000
I42.8 Other cardiomyopathies
0.682 0.317 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.682 0.317 0.000
I42.6 Alcoholic cardiomyopathy
0.682 0.317 0.000
I42.5 Other restrictive cardiomyopathy
0.682 0.317 0.000
I42.4 Endocardial fibroelastosis
0.682 0.317 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.682 0.317 0.000
I42.2 Other hypertrophic cardiomyopathy
0.682 0.317 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.682 0.317 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.682 0.318 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.682 0.318 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.682 0.318 0.000
I47.2 Ventricular tachycardia
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.680 0.319 0.000
F32 Depressive episode
0.679 0.321 0.000
C18.2 Ascending colon
0.679 0.321 0.000
M94 Other disorders of cartilage
0.679 0.321 0.000
E70-E90 Metabolic disorders
0.678 0.322 0.000
C15.9 Oesophagus, unspecified
0.678 0.322 0.000
F99-F99 Unspecified mental disorder
0.678 0.322 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.675 0.325 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.675 0.325 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.675 0.325 0.000
F60 Specific personality disorders
0.675 0.325 0.000
T79-T79 Certain early complications of trauma
0.674 0.325 0.000
J41 Simple and mucopurulent chronic bronchitis
0.674 0.326 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.674 0.326 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.673 0.327 0.000
Z36.9 Antenatal screening, unspecified
0.673 0.327 0.000
M45-M49 Spondylopathies
0.673 0.327 0.000
Z45.2 Adjustment and management of vascular access device
0.672 0.328 0.000
R60.0 Localised oedema
0.672 0.328 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.672 0.328 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.670 0.330 0.000
B25-B34 Other viral diseases
0.669 0.331 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.668 0.332 0.000
T18 Foreign body in alimentary tract
0.668 0.332 0.000
Z50.5 Speech therapy
0.668 0.332 0.000
I77.1 Stricture of artery
0.668 0.332 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.667 0.332 0.000
I34.0 Mitral (valve) insufficiency
0.667 0.333 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.667 0.333 0.000
Z10 Routine general health check-up of defined subpopulation
0.666 0.334 0.000
C25 Malignant neoplasm of pancreas
0.666 0.334 0.000
O74 Complications of anaesthesia during labour and delivery
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.666 0.334 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.666 0.334 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.666 0.334 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.666 0.334 0.000
O61 Failed induction of labour
0.666 0.334 0.000
O60 Preterm delivery
0.666 0.334 0.000
G90-G99 Other disorders of the nervous system
0.666 0.334 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.666 0.334 0.000
M76 Enthesopathies of lower limb, excluding foot
0.665 0.335 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.665 0.335 0.000
M71 Other bursopathies
0.665 0.335 0.000
Z54 Convalescence
0.664 0.336 0.000
Z44 Fitting and adjustment of external prosthetic device
0.664 0.336 0.000
D75.2 Essential thrombocytosis
0.664 0.336 0.000
T17 Foreign body in respiratory tract
0.664 0.336 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.663 0.337 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.663 0.337 0.000
R77 Other abnormalities of plasma proteins
0.663 0.337 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.663 0.337 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.663 0.337 0.000
R71 Abnormality of red blood cells
0.663 0.337 0.000
O21.0 Mild hyperemesis gravidarum
0.663 0.337 0.000
I27.0 Primary pulmonary hypertension
0.662 0.338 0.000
I44.7 Left bundle-branch block, unspecified
0.662 0.338 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.662 0.338 0.000
I22 Subsequent myocardial infarction
0.661 0.339 0.000
Z03.3 Observation for suspected nervous system disorder
0.661 0.339 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.660 0.339 0.000
J18.8 Other pneumonia, organism unspecified
0.660 0.340 0.000
J18.2 Hypostatic pneumonia, unspecified
0.660 0.340 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.660 0.340 0.000
O62.2 Other uterine inertia
0.660 0.340 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
C77.3 Axillary and upper limb lymph nodes
0.658 0.342 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.658 0.342 0.000
M14 Arthropathies in other diseases classified elsewhere
0.658 0.342 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.658 0.342 0.000
M08 Juvenile arthritis
0.658 0.342 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.658 0.342 0.000
O30 Multiple gestation
0.657 0.342 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.657 0.343 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.657 0.343 0.000
M65 Synovitis and tenosynovitis
0.656 0.343 0.000
I26 Pulmonary embolism
0.656 0.344 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.656 0.344 0.000
D61 Other aplastic anaemias
0.656 0.344 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.655 0.344 0.000
H53-H54 Visual disturbances and blindness
0.655 0.345 0.000
O80-O84 Delivery
0.655 0.345 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.654 0.345 0.000
Z50.6 Orthoptic training
0.654 0.346 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.654 0.346 0.000
Z50.3 Drug rehabilitation
0.654 0.346 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.653 0.347 0.000
Z52 Donors of organs and tissues
0.653 0.347 0.000
M77 Other enthesopathies
0.653 0.347 0.000
I73.8 Other specified peripheral vascular diseases
0.652 0.347 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.652 0.347 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.652 0.348 0.000
D63.0 Anaemia in neoplastic disease
0.652 0.348 0.000
C50-C50 Malignant neoplasm of breast
0.651 0.349 0.000
Z13.1 Special screening examination for diabetes mellitus
0.651 0.349 0.000
Z03.4 Observation for suspected myocardial infarction
0.650 0.350 0.000
I34.1 Mitral (valve) prolapse
0.650 0.350 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.650 0.350 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.650 0.350 0.000
T39.4 Antirheumatics, not elsewhere classified
0.650 0.350 0.000
T39.2 Pyrazolone derivatives
0.650 0.350 0.000
O36 Maternal care for other known or suspected foetal problems
0.650 0.350 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.649 0.351 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.649 0.351 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.649 0.351 0.000
O34.6 Maternal care for abnormality of vagina
0.649 0.351 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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