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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61748588
log Bayes Factor = 24.9135
Chromosome 6   position 30,878,523  (GRCh37) Explore rs61748588 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z88.0 Personal history of allergy to penicillin
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.993 0.007 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.992 0.008 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.991 0.009 0.000
C44 Other malignant neoplasms of skin
0.988 0.012 0.000
C44.3 Skin of other and unspecified parts of face
0.988 0.012 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.982 0.018 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.981 0.019 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.981 0.019 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.980 0.020 0.000
Z03.8 Observation for other suspected diseases and conditions
0.976 0.024 0.000
F30-F39 Mood [affective] disorders
0.973 0.027 0.000
N20-N23 Urolithiasis
0.968 0.032 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.966 0.034 0.000
B95-B98 Bacterial, viral and other infectious agents
0.962 0.038 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.959 0.041 0.000
Chapter IX Diseases of the circulatory system
0.958 0.042 0.000
S00-S09 Injuries to the head
0.952 0.048 0.000
S80-S89 Injuries to the knee and lower leg
0.945 0.055 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.943 0.057 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.943 0.057 0.000
Chapter XX External causes of morbidity and mortality
0.943 0.057 0.000
N10-N16 Renal tubulo-interstitial diseases
0.940 0.060 0.000
F31 Bipolar affective disorder
0.939 0.061 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.937 0.063 0.000
D00-D09 In situ neoplasms
0.936 0.064 0.000
R05 Cough
0.935 0.065 0.000
N95 Menopausal and other perimenopausal disorders
0.934 0.066 0.000
M13 Other arthritis
0.933 0.067 0.000
A30-A49 Other bacterial diseases
0.929 0.071 0.000
R06 Abnormalities of breathing
0.929 0.071 0.000
N80 Endometriosis
0.928 0.072 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.928 0.072 0.000
N60-N64 Disorders of breast
0.927 0.073 0.000
Z03.4 Observation for suspected myocardial infarction
0.920 0.080 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.919 0.081 0.000
Z51 Other medical care
0.919 0.081 0.000
E65-E68 Obesity and other hyperalimentation
0.919 0.081 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.913 0.087 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.911 0.089 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.908 0.092 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.906 0.094 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.905 0.095 0.000
M20-M25 Other joint disorders
0.904 0.096 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.902 0.098 0.000
N20 Calculus of kidney and ureter
0.898 0.102 0.000
M13.9 Arthritis, unspecified
0.896 0.104 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.894 0.106 0.000
Z92 Personal history of medical treatment
0.894 0.106 0.000
E20-E35 Disorders of other endocrine glands
0.890 0.110 0.000
M05 Seropositive rheumatoid arthritis
0.889 0.111 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.889 0.111 0.000
N23 Unspecified renal colic
0.887 0.113 0.000
Chapter X Diseases of the respiratory system
0.886 0.114 0.000
S60-S69 Injuries to the wrist and hand
0.886 0.114 0.000
R26 Abnormalities of gait and mobility
0.886 0.114 0.000
R06.5 Mouth breathing
0.885 0.115 0.000
E66 Obesity
0.885 0.115 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.884 0.116 0.000
S06 Intracranial injury
0.882 0.118 0.000
F41 Other anxiety disorders
0.880 0.120 0.000
M45-M49 Spondylopathies
0.880 0.120 0.000
F33 Recurrent depressive disorder
0.880 0.120 0.000
N84 Polyp of female genital tract
0.878 0.122 0.000
F31.9 Bipolar affective disorder, unspecified
0.875 0.125 0.000
Z50 Care involving use of rehabilitation procedures
0.871 0.129 0.000
S01 Open wound of head
0.869 0.131 0.000
Z51.2 Other chemotherapy
0.868 0.132 0.000
Chapter VI Diseases of the nervous system
0.867 0.133 0.000
Chapter VII Diseases of the eye and adnexa
0.866 0.134 0.000
N80.9 Endometriosis, unspecified
0.866 0.134 0.000
A41 Other septicaemia
0.866 0.134 0.000
Z51.0 Radiotherapy session
0.863 0.137 0.000
N95.0 Postmenopausal bleeding
0.862 0.138 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.853 0.147 0.000
J95-J99 Other diseases of the respiratory system
0.852 0.148 0.000
F41.2 Mixed anxiety and depressive disorder
0.847 0.153 0.000
M25 Other joint disorders, not elsewhere classified
0.847 0.153 0.000
B25-B34 Other viral diseases
0.846 0.154 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.843 0.157 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.842 0.158 0.000
M70-M79 Other soft tissue disorders
0.841 0.159 0.000
N10 Acute tubulo-interstitial nephritis
0.840 0.160 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.840 0.160 0.000
N94.6 Dysmenorrhoea, unspecified
0.839 0.161 0.000
R09.1 Pleurisy
0.838 0.162 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.837 0.163 0.000
Z97 Presence of other devices
0.836 0.164 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.834 0.166 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.834 0.166 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.834 0.166 0.000
T79-T79 Certain early complications of trauma
0.833 0.167 0.000
D06 Carcinoma in situ of cervix uteri
0.833 0.167 0.000
C44.4 Skin of scalp and neck
0.831 0.169 0.000
I84 Haemorrhoids
0.831 0.169 0.000
Z04 Examination and observation for other reasons
0.831 0.169 0.000
Z46 Fitting and adjustment of other devices
0.829 0.171 0.000
J98 Other respiratory disorders
0.828 0.172 0.000
E66.8 Other obesity
0.828 0.172 0.000
R47-R49 Symptoms and signs involving speech and voice
0.827 0.172 0.000
I26 Pulmonary embolism
0.825 0.175 0.000
N84.1 Polyp of cervix uteri
0.824 0.176 0.000
M40-M43 Deforming dorsopathies
0.824 0.176 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.824 0.176 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.822 0.178 0.000
B15-B19 Viral hepatitis
0.821 0.179 0.000
Z72 Problems related to lifestyle
0.821 0.179 0.000
S82 Fracture of lower leg, including ankle
0.820 0.180 0.000
R02 Gangrene, not elsewhere classified
0.820 0.180 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.820 0.180 0.000
M23 Internal derangement of knee
0.819 0.181 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.814 0.186 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.814 0.186 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.811 0.189 0.000
H53-H54 Visual disturbances and blindness
0.808 0.192 0.000
M25.7 Osteophyte
0.808 0.192 0.000
N97 Female infertility
0.807 0.193 0.000
M06 Other rheumatoid arthritis
0.805 0.195 0.000
N20.0 Calculus of kidney
0.803 0.197 0.000
R04 Haemorrhage from respiratory passages
0.803 0.197 0.000
N85.4 Malposition of uterus
0.801 0.199 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.800 0.200 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.800 0.200 0.000
M13.94 Arthritis, unspecified (Hand)
0.799 0.201 0.000
J98.1 Pulmonary collapse
0.798 0.202 0.000
F33.9 Recurrent depressive disorder, unspecified
0.797 0.203 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.795 0.205 0.000
Z50.8 Care involving use of rehabilitation procedures
0.794 0.206 0.000
Z48 Other surgical follow-up care
0.794 0.206 0.000
Z74 Problems related to care-provider dependency
0.793 0.207 0.000
G20-G26 Extrapyramidal and movement disorders
0.791 0.209 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
B35-B49 Mycoses
0.790 0.210 0.000
D45 Polycythaemia vera
0.789 0.211 0.000
W00-W19 Falls
0.788 0.212 0.000
S06.5 Traumatic subdural haemorrhage
0.788 0.212 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.786 0.214 0.000
Chapter VIII Diseases of the ear and mastoid process
0.786 0.214 0.000
N20.1 Calculus of ureter
0.785 0.215 0.000
N86 Erosion and ectropion of cervix uteri
0.783 0.217 0.000
N64 Other disorders of breast
0.782 0.218 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.780 0.220 0.000
I81 Portal vein thrombosis
0.779 0.221 0.000
E66.9 Obesity, unspecified
0.779 0.221 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
T66-T78 Other and unspecified effects of external causes
0.778 0.222 0.000
C60-C63 Malignant neoplasms of male genital organs
0.778 0.222 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.777 0.223 0.000
M00-M03 Infectious arthropathies
0.776 0.224 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.776 0.224 0.000
S20-S29 Injuries to the thorax
0.774 0.226 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.773 0.227 0.000
N13 Obstructive and reflux uropathy
0.773 0.227 0.000
F80-F89 Disorders of psychological development
0.770 0.230 0.000
S80 Superficial injury of lower leg
0.770 0.230 0.000
N30-N39 Other diseases of urinary system
0.768 0.232 0.000
M47 Spondylosis
0.766 0.234 0.000
H53 Visual disturbances
0.765 0.235 0.000
F40 Phobic anxiety disorders
0.764 0.236 0.000
Chapter XXII Codes for special purposes
0.764 0.236 0.000
M75 Shoulder lesions
0.762 0.238 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.762 0.238 0.000
M13.98 Arthritis, unspecified (Other)
0.761 0.239 0.000
S64 Injury of nerves at wrist and hand level
0.760 0.240 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.759 0.241 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.759 0.241 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
D06.9 Cervix, unspecified
0.759 0.241 0.000
Z94 Transplanted organ and tissue status
0.759 0.241 0.000
C01 Malignant neoplasm of base of tongue
0.758 0.242 0.000
Z75 Problems related to medical facilities and other health care
0.757 0.243 0.000
I84.1 Internal haemorrhoids with other complications
0.757 0.243 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.757 0.243 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.757 0.243 0.000
Z88.6 Personal history of allergy to analgesic agent
0.756 0.244 0.000
N60 Benign mammary dysplasia
0.756 0.244 0.000
J09-J18 Influenza and pneumonia
0.755 0.245 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.755 0.245 0.000
S40-S49 Injuries to the shoulder and upper arm
0.755 0.245 0.000
E23 Hypofunction and other disorders of pituitary gland
0.755 0.245 0.000
C09 Malignant neoplasm of tonsil
0.755 0.245 0.000
F03 Unspecified dementia
0.754 0.246 0.000
S01.5 Open wound of lip and oral cavity
0.754 0.246 0.000
N62 Hypertrophy of breast
0.754 0.246 0.000
N61 Inflammatory disorders of breast
0.753 0.247 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.753 0.247 0.000
C43 Malignant melanoma of skin
0.753 0.247 0.000
D04 Carcinoma in situ of skin
0.752 0.248 0.000
E29 Testicular dysfunction
0.752 0.248 0.000
M07 Psoriatic and enteropathic arthropathies
0.749 0.250 0.000
N95.2 Postmenopausal atrophic vaginitis
0.745 0.254 0.000
X20-X29 Contact with venomous animals and plants
0.745 0.255 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.745 0.255 0.000
R47 Speech disturbances, not elsewhere classified
0.745 0.255 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.744 0.256 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.744 0.256 0.000
M25.76 Osteophyte (Lower leg)
0.743 0.257 0.000
D37.4 Colon
0.742 0.258 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.742 0.258 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
D03 Melanoma in situ
0.741 0.259 0.000
N92 Excessive, frequent and irregular menstruation
0.740 0.259 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.739 0.261 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.739 0.261 0.000
B34 Viral infection of unspecified site
0.738 0.262 0.000
G20 Parkinson's disease
0.737 0.263 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.736 0.264 0.000
Z46.6 Fitting and adjustment of urinary device
0.735 0.265 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.734 0.266 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.734 0.266 0.000
R01 Cardiac murmurs and other cardiac sounds
0.734 0.266 0.000
I95 Hypotension
0.733 0.267 0.000
Z89 Acquired absence of limb
0.732 0.267 0.000
Z50.1 Other physical therapy
0.732 0.268 0.000
S02 Fracture of skull and facial bones
0.732 0.268 0.000
I86 Varicose veins of other sites
0.731 0.269 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.731 0.269 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.730 0.269 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.730 0.270 0.000
N80.8 Other endometriosis
0.729 0.271 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.729 0.271 0.000
Z45 Adjustment and management of implanted device
0.728 0.272 0.000
A49 Bacterial infection of unspecified site
0.727 0.273 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.727 0.273 0.000
Z22 Carrier of infectious disease
0.725 0.275 0.000
C44.0 Skin of lip
0.724 0.275 0.000
M48 Other spondylopathies
0.724 0.276 0.000
G90-G99 Other disorders of the nervous system
0.724 0.276 0.000
R41.0 Disorientation, unspecified
0.723 0.277 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.723 0.277 0.000
Z83 Family history of other specific disorders
0.723 0.277 0.000
M22 Disorders of patella
0.722 0.277 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.722 0.278 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.722 0.278 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.721 0.279 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.721 0.279 0.000
N80.2 Endometriosis of Fallopian tube
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.719 0.281 0.000
H10-H13 Disorders of conjunctiva
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
M23.3 Other meniscus derangements
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
F00 Dementia in Alzheimer's disease
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
Z72.2 Drug use
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
M10 Gout
0.715 0.285 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.715 0.285 0.000
D09 Carcinoma in situ of other and unspecified sites
0.715 0.285 0.000
F99-F99 Unspecified mental disorder
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
Z92.3 Personal history of irradiation
0.715 0.285 0.000
M11 Other crystal arthropathies
0.714 0.286 0.000
A00-A09 Intestinal infectious diseases
0.714 0.286 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.714 0.286 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.713 0.286 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.712 0.288 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.712 0.288 0.000
N98 Complications associated with artificial fertilisation
0.711 0.289 0.000
N91 Absent, scanty and rare menstruation
0.711 0.289 0.000
N82 Fistulae involving female genital tract
0.711 0.289 0.000
N96 Habitual aborter
0.711 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.711 0.289 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.711 0.289 0.000
R26.0 Ataxic gait
0.710 0.290 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.708 0.292 0.000
C44.8 Overlapping lesion of skin
0.708 0.292 0.000
I85 Oesophageal varices
0.708 0.292 0.000
N80.3 Endometriosis of pelvic peritoneum
0.707 0.292 0.000
S06.2 Diffuse brain injury
0.707 0.293 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.293 0.000
M12 Other specific arthropathies
0.706 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.293 0.000
M08 Juvenile arthritis
0.706 0.293 0.000
I82 Other venous embolism and thrombosis
0.706 0.294 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.706 0.294 0.000
N80.1 Endometriosis of ovary
0.705 0.295 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.705 0.295 0.000
M80-M85 Disorders of bone density and structure
0.704 0.296 0.000
M75.4 Impingement syndrome of shoulder
0.704 0.296 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.704 0.296 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.704 0.296 0.000
Z10 Routine general health check-up of defined subpopulation
0.703 0.297 0.000
Z84 Family history of other conditions
0.703 0.297 0.000
Z81 Family history of mental and behavioural disorders
0.703 0.297 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.703 0.297 0.000
Z03.3 Observation for suspected nervous system disorder
0.703 0.297 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.703 0.297 0.000
Z03.0 Observation for suspected tuberculosis
0.703 0.297 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.703 0.297 0.000
N75 Diseases of Bartholin's gland
0.703 0.297 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.702 0.298 0.000
E50-E64 Other nutritional deficiencies
0.701 0.299 0.000
R00 Abnormalities of heart beat
0.701 0.299 0.000
S50-S59 Injuries to the elbow and forearm
0.701 0.299 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.701 0.299 0.000
S82.8 Fractures of other parts of lower leg
0.700 0.300 0.000
S90-S99 Injuries to the ankle and foot
0.699 0.301 0.000
F43 Reaction to severe stress, and adjustment disorders
0.698 0.302 0.000
F38 Other mood [affective] disorders
0.697 0.303 0.000
F34 Persistent mood [affective] disorders
0.697 0.303 0.000
F30 Manic episode
0.697 0.303 0.000
F39 Unspecified mood [affective] disorder
0.697 0.303 0.000
N64.1 Fat necrosis of breast
0.697 0.303 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.697 0.303 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.696 0.304 0.000
N71 Inflammatory disease of uterus, except cervix
0.695 0.305 0.000
J98.4 Other disorders of lung
0.695 0.305 0.000
Z52 Donors of organs and tissues
0.695 0.305 0.000
E70-E90 Metabolic disorders
0.695 0.305 0.000
S81 Open wound of lower leg
0.695 0.305 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.694 0.306 0.000
N17-N19 Renal failure
0.694 0.306 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.694 0.306 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.307 0.000
E40-E46 Malnutrition
0.692 0.308 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.692 0.308 0.000
M50-M54 Other dorsopathies
0.692 0.308 0.000
I84.9 Unspecified haemorrhoids without complication
0.692 0.308 0.000
S82.6 Fracture of lateral malleolus
0.692 0.308 0.000
I27 Other pulmonary heart diseases
0.691 0.309 0.000
M86-M90 Other osteopathies
0.691 0.309 0.000
R47.8 Other and unspecified speech disturbances
0.691 0.309 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.691 0.309 0.000
Z48.8 Other specified surgical follow-up care
0.690 0.310 0.000
S89 Other and unspecified injuries of lower leg
0.690 0.310 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.690 0.310 0.000
Chapter XI Diseases of the digestive system
0.690 0.310 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.690 0.310 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.689 0.311 0.000
Z74.0 Reduced mobility
0.689 0.311 0.000
G30-G32 Other degenerative diseases of the nervous system
0.688 0.312 0.000
Z72.1 Alcohol use
0.688 0.312 0.000
Z54 Convalescence
0.688 0.312 0.000
Z49 Care involving dialysis
0.688 0.312 0.000
Z44 Fitting and adjustment of external prosthetic device
0.688 0.312 0.000
I00-I02 Acute rheumatic fever
0.687 0.313 0.000
H60-H62 Diseases of external ear
0.687 0.313 0.000
S01.9 Open wound of head, part unspecified
0.687 0.313 0.000
Y52 Agents primarily affecting the cardiovascular system
0.687 0.313 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.687 0.313 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.687 0.313 0.000
Z92.8 Personal history of other medical treatment
0.686 0.313 0.000
N99-N99 Other disorders of the genitourinary system
0.685 0.315 0.000
I87 Other disorders of veins
0.684 0.316 0.000
Z73 Problems related to life-management difficulty
0.683 0.317 0.000
Z04.3 Examination and observation following other accident
0.683 0.317 0.000
S08 Traumatic amputation of part of head
0.682 0.318 0.000
S07 Crushing injury of head
0.682 0.318 0.000
S05 Injury of eye and orbit
0.682 0.318 0.000
S04 Injury of cranial nerves
0.682 0.318 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.682 0.318 0.000
H53.0 Amblyopia ex anopsia
0.682 0.318 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.682 0.318 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.681 0.319 0.000
I05-I09 Chronic rheumatic heart diseases
0.681 0.319 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.681 0.319 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.680 0.320 0.000
Z85 Personal history of malignant neoplasm
0.679 0.321 0.000
N30 Cystitis
0.679 0.321 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
Z98 Other postsurgical states
0.679 0.321 0.000
R40 Somnolence, stupor and coma
0.678 0.322 0.000
A41.9 Septicaemia, unspecified
0.678 0.322 0.000
Y57 Other and unspecified drugs and medicaments
0.678 0.322 0.000
S88 Traumatic amputation of lower leg
0.677 0.323 0.000
S87 Crushing injury of lower leg
0.677 0.323 0.000
S86 Injury of muscle and tendon at lower leg level
0.677 0.323 0.000
S85 Injury of blood vessels at lower leg level
0.677 0.323 0.000
S84 Injury of nerves at lower leg level
0.677 0.323 0.000
R09.0 Asphyxia
0.677 0.323 0.000
F48 Other neurotic disorders
0.676 0.324 0.000
F45 Somatoform disorders
0.676 0.324 0.000
F44 Dissociative [conversion] disorders
0.676 0.324 0.000
F42 Obsessive-compulsive disorder
0.676 0.324 0.000
D46 Myelodysplastic syndromes
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.676 0.324 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.676 0.324 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.676 0.324 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.676 0.324 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.676 0.324 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.676 0.324 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.676 0.324 0.000
Y35-Y36 Legal intervention and operations of war
0.676 0.324 0.000
Y10-Y34 Event of undetermined intent
0.676 0.324 0.000
Y00-Y09 Assault
0.676 0.324 0.000
X85-X99 Assault
0.676 0.324 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.676 0.324 0.000
X50-X57 Overexertion, travel and privation
0.676 0.324 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.676 0.324 0.000
X30-X39 Exposure to forces of nature
0.676 0.324 0.000
X10-X19 Contact with heat and hot substances
0.676 0.324 0.000
X00-X09 Exposure to smoke, fire and flames
0.676 0.324 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.676 0.324 0.000
W75-W84 Other accidental threats to breathing
0.676 0.324 0.000
W65-W74 Accidental drowning and submersion
0.676 0.324 0.000
W50-W64 Exposure to animate mechanical forces
0.676 0.324 0.000
V98-V99 Other and unspecified transport accidents
0.676 0.324 0.000
V95-V97 Air and space transport accidents
0.676 0.324 0.000
V90-V94 Water transport accidents
0.676 0.324 0.000
V80-V89 Other land transport accidents
0.676 0.324 0.000
V70-V79 Bus occupant injured in transport accident
0.676 0.324 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.676 0.324 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.676 0.324 0.000
V40-V49 Car occupant injured in transport accident
0.676 0.324 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.676 0.324 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
V01-V09 Pedestrian injured in transport accident
0.676 0.324 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.675 0.325 0.000
S01.0 Open wound of scalp
0.674 0.326 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.674 0.326 0.000
N15 Other renal tubulo-interstitial diseases
0.674 0.326 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.674 0.326 0.000
N11 Chronic tubulo-interstitial nephritis
0.674 0.326 0.000
I80 Phlebitis and thrombophlebitis
0.674 0.326 0.000
D10-D36 Benign neoplasms
0.674 0.326 0.000
F31.8 Other bipolar affective disorders
0.673 0.326 0.000
F31.7 Bipolar affective disorder, currently in remission
0.673 0.326 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.673 0.326 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.673 0.326 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.673 0.326 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.673 0.326 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.673 0.327 0.000
M43 Other deforming dorsopathies
0.672 0.328 0.000
S01.1 Open wound of eyelid and periocular area
0.672 0.328 0.000
Z76 Persons encountering health services in other circumstances
0.672 0.328 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.672 0.328 0.000
I20-I25 Ischaemic heart diseases
0.671 0.329 0.000
R04.2 Haemoptysis
0.671 0.329 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.671 0.329 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.671 0.329 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.671 0.329 0.000
N85.2 Hypertrophy of uterus
0.671 0.329 0.000
R21 Rash and other nonspecific skin eruption
0.670 0.330 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.670 0.330 0.000
N95.3 States associated with artificial menopause
0.670 0.330 0.000
N95.1 Menopausal and female climacteric states
0.670 0.330 0.000
Z43 Attention to artificial openings
0.669 0.330 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.669 0.331 0.000
N21 Calculus of lower urinary tract
0.669 0.331 0.000
M13.8 Other specified arthritis
0.669 0.331 0.000
M13.1 Monoarthritis, not elsewhere classified
0.669 0.331 0.000
M13.0 Polyarthritis, unspecified
0.669 0.331 0.000
R20 Disturbances of skin sensation
0.669 0.331 0.000
R06.4 Hyperventilation
0.669 0.331 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.668 0.332 0.000
Z13 Special screening examination for other diseases and disorders
0.668 0.332 0.000
F01 Vascular dementia
0.668 0.332 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.667 0.333 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.666 0.333 0.000
A48 Other bacterial diseases, not elsewhere classified
0.666 0.334 0.000
A44 Bartonellosis
0.666 0.334 0.000
A43 Nocardiosis
0.666 0.334 0.000
A42 Actinomycosis
0.666 0.334 0.000
A40 Streptococcal septicaemia
0.666 0.334 0.000
A39 Meningococcal infection
0.666 0.334 0.000
A37 Whooping cough
0.666 0.334 0.000
A36 Diphtheria
0.666 0.334 0.000
A32 Listeriosis
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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