TreeWAS – Variant ID: rs6903496

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.987	0.013	0.000
Chapter IX Diseases of the circulatory system	0.964	0.036	0.000
Chapter VI Diseases of the nervous system	0.954	0.046	0.000
S60-S69 Injuries to the wrist and hand	0.947	0.053	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.942	0.058	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.941	0.059	0.000
S40-S49 Injuries to the shoulder and upper arm	0.940	0.060	0.000
Chapter II Neoplasms	0.940	0.060	0.000
E10.4 With neurological complications	0.936	0.064	0.000
G35 Multiple sclerosis	0.931	0.069	0.000
E14 Unspecified diabetes mellitus	0.923	0.077	0.000
C15-C26 Malignant neoplasms of digestive organs	0.918	0.082	0.000
S42 Fracture of shoulder and upper arm	0.904	0.096	0.000
E16 Other disorders of pancreatic internal secretion	0.900	0.100	0.000
S50-S59 Injuries to the elbow and forearm	0.899	0.101	0.000
S20-S29 Injuries to the thorax	0.895	0.105	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.895	0.105	0.000
I20-I25 Ischaemic heart diseases	0.889	0.111	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.888	0.112	0.000
E10.1 With ketoacidosis	0.888	0.112	0.000
Chapter V Mental and behavioural disorders	0.883	0.117	0.000
Chapter XX External causes of morbidity and mortality	0.880	0.120	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.879	0.121	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.878	0.122	0.000
E16.2 Hypoglycaemia, unspecified	0.870	0.130	0.000
E14.9 Without complications	0.857	0.143	0.000
E10.5 With peripheral circulatory complications	0.854	0.146	0.000
C25 Malignant neoplasm of pancreas	0.829	0.171	0.000
S42.0 Fracture of clavicle	0.826	0.174	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.826	0.174	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.823	0.177	0.000
S52 Fracture of forearm	0.823	0.177	0.000
I21 Acute myocardial infarction	0.818	0.182	0.000
S60 Superficial injury of wrist and hand	0.816	0.184	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.816	0.184	0.000
C44 Other malignant neoplasms of skin	0.815	0.185	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.814	0.186	0.000
I21.9 Acute myocardial infarction, unspecified	0.806	0.194	0.000
S61 Open wound of wrist and hand	0.801	0.199	0.000
Chapter I Certain infectious and parasitic diseases	0.799	0.201	0.000
F30-F39 Mood [affective] disorders	0.797	0.203	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.797	0.203	0.000
I71 Aortic aneurysm and dissection	0.792	0.208	0.000
E07 Other disorders of thyroid	0.791	0.209	0.000
W00-W19 Falls	0.790	0.210	0.000
T66-T78 Other and unspecified effects of external causes	0.786	0.214	0.000
S42.2 Fracture of upper end of humerus	0.785	0.215	0.000
I74 Arterial embolism and thrombosis	0.783	0.217	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.779	0.221	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.778	0.221	0.000
Chapter VII Diseases of the eye and adnexa	0.778	0.222	0.000
I25 Chronic ischaemic heart disease	0.775	0.225	0.000
S42.00 Fracture of clavicle (closed)	0.771	0.229	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.771	0.229	0.000
Chapter XXII Codes for special purposes	0.770	0.230	0.000
I24 Other acute ischaemic heart diseases	0.770	0.230	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.768	0.232	0.000
S64 Injury of nerves at wrist and hand level	0.767	0.233	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.766	0.234	0.000
C18 Malignant neoplasm of colon	0.766	0.234	0.000
I60-I69 Cerebrovascular diseases	0.766	0.234	0.000
G90-G99 Other disorders of the nervous system	0.764	0.236	0.000
C44.1 Skin of eyelid, including canthus	0.763	0.237	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.762	0.238	0.000
G30-G32 Other degenerative diseases of the nervous system	0.758	0.242	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.758	0.242	0.000
W20-W49 Exposure to inanimate mechanical forces	0.757	0.243	0.000
E65-E68 Obesity and other hyperalimentation	0.753	0.246	0.000
T79-T79 Certain early complications of trauma	0.752	0.248	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.748	0.252	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.748	0.252	0.000
I05-I09 Chronic rheumatic heart diseases	0.746	0.254	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.744	0.256	0.000
I25.2 Old myocardial infarction	0.744	0.256	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.743	0.257	0.000
I80 Phlebitis and thrombophlebitis	0.738	0.262	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.737	0.262	0.000
C15 Malignant neoplasm of oesophagus	0.736	0.264	0.000
E20-E35 Disorders of other endocrine glands	0.736	0.264	0.000
C44.7 Skin of lower limb, including hip	0.732	0.268	0.000
H30-H36 Disorders of choroid and retina	0.729	0.271	0.000
S52.5 Fracture of lower end of radius	0.729	0.271	0.000
S90-S99 Injuries to the ankle and foot	0.728	0.272	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.725	0.275	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.723	0.277	0.000
E40-E46 Malnutrition	0.723	0.277	0.000
C50-C50 Malignant neoplasm of breast	0.723	0.277	0.000
F31 Bipolar affective disorder	0.722	0.278	0.000
S42.1 Fracture of scapula	0.721	0.279	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.719	0.281	0.000
Chapter XIV Diseases of the genitourinary system	0.718	0.282	0.000
E10.8 With unspecified complications	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E10.2 With renal complications	0.717	0.283	0.000
E10.0 With coma	0.717	0.283	0.000
E13 Other specified diabetes mellitus	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
C44.0 Skin of lip	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.8 Other specified hypothyroidism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.283	0.000
S10-S19 Injuries to the neck	0.716	0.283	0.000
I70 Atherosclerosis	0.716	0.284	0.000
C25.9 Pancreas, unspecified	0.713	0.287	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.711	0.289	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.710	0.290	0.000
I82 Other venous embolism and thrombosis	0.710	0.290	0.000
H36 Retinal disorders in diseases classified elsewhere	0.708	0.292	0.000
E14.3 With ophthalmic complications	0.706	0.294	0.000
S20 Superficial injury of thorax	0.703	0.297	0.000
G37 Other demyelinating diseases of central nervous system	0.703	0.297	0.000
I74.5 Embolism and thrombosis of iliac artery	0.702	0.298	0.000
S68 Traumatic amputation of wrist and hand	0.702	0.298	0.000
C43 Malignant melanoma of skin	0.701	0.299	0.000
S42.20 Fracture of upper end of humerus (closed)	0.701	0.299	0.000
I86 Varicose veins of other sites	0.700	0.300	0.000
C25.0 Head of pancreas	0.698	0.302	0.000
C34 Malignant neoplasm of bronchus and lung	0.695	0.305	0.000
S52.6 Fracture of lower end of both ulna and radius	0.693	0.307	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.693	0.307	0.000
H36.0 Diabetic retinopathy	0.692	0.308	0.000
I00-I02 Acute rheumatic fever	0.691	0.309	0.000
S60.8 Other superficial injuries of wrist and hand	0.690	0.310	0.000
X20-X29 Contact with venomous animals and plants	0.688	0.312	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.687	0.313	0.000
G70-G73 Diseases of myoneural junction and muscle	0.684	0.316	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.684	0.316	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.683	0.317	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.683	0.317	0.000
N17-N19 Renal failure	0.683	0.317	0.000
S27 Injury of other and unspecified intrathoracic organs	0.683	0.317	0.000
S40 Superficial injury of shoulder and upper arm	0.682	0.318	0.000
A00-A09 Intestinal infectious diseases	0.681	0.318	0.001
D00-D09 In situ neoplasms	0.681	0.319	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.681	0.319	0.000
S69 Other and unspecified injuries of wrist and hand	0.679	0.321	0.000
S67 Crushing injury of wrist and hand	0.679	0.321	0.000
S65 Injury of blood vessels at wrist and hand level	0.679	0.321	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.678	0.322	0.000
I81 Portal vein thrombosis	0.677	0.323	0.000
E15 Nondiabetic hypoglycaemic coma	0.675	0.325	0.000
G36 Other acute disseminated demyelination	0.675	0.325	0.000
S42.3 Fracture of shaft of humerus	0.674	0.326	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.674	0.326	0.000
S48 Traumatic amputation of shoulder and upper arm	0.674	0.326	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.674	0.326	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.674	0.326	0.000
S44 Injury of nerves at shoulder and upper arm level	0.674	0.326	0.000
S41 Open wound of shoulder and upper arm	0.674	0.326	0.000
S47 Crushing injury of shoulder and upper arm	0.674	0.326	0.000
S80-S89 Injuries to the knee and lower leg	0.674	0.326	0.000
Q00-Q07 Congenital malformations of the nervous system	0.674	0.326	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.674	0.326	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.674	0.326	0.000
I72 Other aneurysm	0.671	0.329	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.669	0.331	0.000
E06 Thyroiditis	0.669	0.331	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.668	0.332	0.000
V40-V49 Car occupant injured in transport accident	0.667	0.332	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.667	0.333	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.666	0.334	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.666	0.334	0.000
I85 Oesophageal varices	0.665	0.335	0.000
F60-F69 Disorders of adult personality and behaviour	0.662	0.338	0.000
E14.8 With unspecified complications	0.662	0.338	0.000
E14.7 With multiple complications	0.662	0.338	0.000
E14.6 With other specified complications	0.662	0.338	0.000
E14.5 With peripheral circulatory complications	0.662	0.338	0.000
E14.4 With neurological complications	0.662	0.338	0.000
E14.2 Withrenal complications	0.662	0.338	0.000
E14.1 With ketoacidosis	0.662	0.338	0.000
E14.0 With coma	0.662	0.338	0.000
S52.50 Fracture of lower end of radius (closed)	0.662	0.338	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.661	0.339	0.000
S50 Superficial injury of forearm	0.659	0.341	0.000
C21 Malignant neoplasm of anus and anal canal	0.658	0.341	0.000
C17 Malignant neoplasm of small intestine	0.658	0.341	0.000
C23 Malignant neoplasm of gallbladder	0.658	0.341	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.658	0.342	0.000
I63 Cerebral infarction	0.657	0.343	0.000
N18 Chronic renal failure	0.656	0.344	0.000
F30 Manic episode	0.655	0.345	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.655	0.345	0.000
Q50-Q56 Congenital malformations of genital organs	0.654	0.346	0.000
W17 Other fall from one level to another	0.654	0.346	0.000
C18.2 Ascending colon	0.653	0.347	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.653	0.347	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.653	0.347	0.000
I77 Other disorders of arteries and arterioles	0.653	0.347	0.000
V10-V19 Pedal cyclist injured in transport accident	0.652	0.348	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.650	0.350	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.649	0.351	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.649	0.351	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.648	0.352	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.648	0.352	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.648	0.352	0.000
S22.1 Multiple fractures of thoracic spine	0.647	0.353	0.000
W19 Unspecified fall	0.647	0.353	0.000
S70-S79 Injuries to the hip and thigh	0.646	0.354	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.646	0.354	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.645	0.355	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.645	0.355	0.000
E16.4 Abnormal secretion of gastrin	0.645	0.355	0.000
E16.3 Increased secretion of glucagon	0.645	0.355	0.000
E16.1 Other hypoglycaemia	0.645	0.355	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.645	0.355	0.000
I87 Other disorders of veins	0.645	0.355	0.000
S59 Other and unspecified injuries of forearm	0.644	0.355	0.000
S58 Traumatic amputation of forearm	0.644	0.355	0.000
S57 Crushing injury of forearm	0.644	0.355	0.000
S56 Injury of muscle and tendon at forearm level	0.644	0.355	0.000
S55 Injury of blood vessels at forearm level	0.644	0.355	0.000
S54 Injury of nerves at forearm level	0.644	0.355	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.644	0.355	0.000
S51 Open wound of forearm	0.644	0.355	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.644	0.356	0.000
C64-C68 Malignant neoplasms of urinary tract	0.643	0.357	0.000
Q60-Q64 Congenital malformations of the urinary system	0.642	0.358	0.000
Q21 Congenital malformations of cardiac septa	0.642	0.358	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.642	0.358	0.000
S29 Other and unspecified injuries of thorax	0.642	0.358	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.642	0.358	0.000
S26 Injury of heart	0.642	0.358	0.000
S25 Injury of blood vessels of thorax	0.642	0.358	0.000
S24 Injury of nerves and spinal cord at thorax level	0.642	0.358	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.642	0.358	0.000
S21 Open wound of thorax	0.642	0.358	0.000
N00-N08 Glomerular diseases	0.641	0.359	0.000
E07.9 Disorder of thyroid, unspecified	0.641	0.359	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.640	0.360	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.640	0.360	0.000
S64.4 Injury of digital nerve of other finger	0.638	0.361	0.000
I23 Certain current complications following acute myocardial infarction	0.637	0.362	0.000
I61 Intracerebral haemorrhage	0.637	0.363	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.637	0.363	0.000
Q80-Q89 Other congenital malformations	0.637	0.363	0.000
Q35-Q37 Cleft lip and cleft palate	0.637	0.363	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.637	0.363	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.637	0.363	0.000
V80-V89 Other land transport accidents	0.636	0.364	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.635	0.365	0.000
T59 Toxic effect of other gases, fumes and vapours	0.634	0.366	0.000
A04 Other bacterial intestinal infections	0.633	0.367	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.633	0.367	0.000
F80-F89 Disorders of psychological development	0.633	0.367	0.000
F70-F79 Mental retardation	0.633	0.367	0.000
T78 Adverse effects, not elsewhere classified	0.633	0.367	0.000
Y35-Y36 Legal intervention and operations of war	0.631	0.369	0.000
Y10-Y34 Event of undetermined intent	0.631	0.369	0.000
Y00-Y09 Assault	0.631	0.369	0.000
X85-X99 Assault	0.631	0.369	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.631	0.369	0.000
X50-X57 Overexertion, travel and privation	0.631	0.369	0.000
X30-X39 Exposure to forces of nature	0.631	0.369	0.000
X10-X19 Contact with heat and hot substances	0.631	0.369	0.000
X00-X09 Exposure to smoke, fire and flames	0.631	0.369	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.631	0.369	0.000
W75-W84 Other accidental threats to breathing	0.631	0.369	0.000
W65-W74 Accidental drowning and submersion	0.631	0.369	0.000
W50-W64 Exposure to animate mechanical forces	0.631	0.369	0.000
V98-V99 Other and unspecified transport accidents	0.631	0.369	0.000
V95-V97 Air and space transport accidents	0.631	0.369	0.000
V90-V94 Water transport accidents	0.631	0.369	0.000
V70-V79 Bus occupant injured in transport accident	0.631	0.369	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.631	0.369	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.631	0.369	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.631	0.369	0.000
V01-V09 Pedestrian injured in transport accident	0.631	0.369	0.000
I88 Nonspecific lymphadenitis	0.630	0.370	0.000
C44.5 Skin of trunk	0.630	0.370	0.000
S52.1 Fracture of upper end of radius	0.628	0.371	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.628	0.372	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.628	0.372	0.000
S61.8 Open wound of other parts of wrist and hand	0.627	0.373	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.626	0.374	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.626	0.374	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.626	0.374	0.000
C24.0 Extrahepatic bile duct	0.626	0.374	0.000
I84 Haemorrhoids	0.625	0.375	0.000
H43-H45 Disorders of vitreous body and globe	0.624	0.376	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.623	0.377	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.622	0.378	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.621	0.379	0.000
T63 Toxic effect of contact with venomous animals	0.621	0.379	0.000
C18.6 Descending colon	0.620	0.380	0.000
A30-A49 Other bacterial diseases	0.620	0.380	0.000
C26.0 Intestinal tract, part unspecified	0.619	0.381	0.000
T51 Toxic effect of alcohol	0.618	0.382	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.614	0.386	0.000
N18.9 Chronic renal failure, unspecified	0.612	0.388	0.000
I25.5 Ischaemic cardiomyopathy	0.611	0.389	0.000
D46 Myelodysplastic syndromes	0.611	0.389	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.611	0.389	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.611	0.389	0.000
H53-H54 Visual disturbances and blindness	0.610	0.390	0.000
G20-G26 Extrapyramidal and movement disorders	0.610	0.390	0.000
V20-V29 Motorcycle rider injured in transport accident	0.610	0.390	0.000
S42.4 Fracture of lower end of humerus	0.610	0.390	0.000
B65-B83 Helminthiases	0.610	0.390	0.000
X60-X84 Intentional self-harm	0.608	0.392	0.000
W10 Fall on and from stairs and steps	0.607	0.393	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.606	0.394	0.000
I24.8 Other forms of acute ischaemic heart disease	0.605	0.395	0.000
H34 Retinal vascular occlusions	0.605	0.395	0.000
F33 Recurrent depressive disorder	0.604	0.395	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.604	0.396	0.000
T81 Complications of procedures, not elsewhere classified	0.604	0.396	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.603	0.397	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.603	0.397	0.000
F99-F99 Unspecified mental disorder	0.601	0.398	0.000
I07 Rheumatic tricuspid valve diseases	0.601	0.399	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.601	0.399	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.600	0.400	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.600	0.400	0.000
N10-N16 Renal tubulo-interstitial diseases	0.599	0.400	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.599	0.401	0.000
C43.4 Malignant melanoma of scalp and neck	0.598	0.402	0.000
H55-H59 Other disorders of eye and adnexa	0.598	0.402	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.598	0.402	0.000
C15.9 Oesophagus, unspecified	0.597	0.403	0.000
W25 Contact with sharp glass	0.596	0.404	0.000
N99-N99 Other disorders of the genitourinary system	0.596	0.404	0.000
C18.4 Transverse colon	0.596	0.404	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.594	0.406	0.000
C25.8 Overlapping lesion of pancreas	0.594	0.406	0.000
C25.7 Other parts of pancreas	0.594	0.406	0.000
C25.4 Endocrine pancreas	0.594	0.406	0.000
C25.3 Pancreatic duct	0.594	0.406	0.000
C25.2 Tail of pancreas	0.594	0.406	0.000
C25.1 Body of pancreas	0.594	0.406	0.000
S22.0 Fracture of thoracic vertebra	0.594	0.406	0.000
S22.4 Multiple fractures of ribs	0.594	0.406	0.000
S00-S09 Injuries to the head	0.593	0.407	0.000
W13 Fall from, out of or through building or structure	0.593	0.407	0.000
T14 Injury of unspecified body region	0.593	0.407	0.000
S42.01 Fracture of clavicle (open)	0.592	0.407	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.592	0.408	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.592	0.408	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.592	0.408	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.592	0.408	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.592	0.408	0.000
S62 Fracture at wrist and hand level	0.592	0.408	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.591	0.409	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.590	0.410	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.590	0.410	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.590	0.410	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.590	0.410	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.590	0.410	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.590	0.410	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.590	0.410	0.000
T36 Poisoning by systemic antibiotics	0.590	0.410	0.000
I25.3 Aneurysm of heart	0.590	0.410	0.000
S42.10 Fracture of scapula (closed)	0.590	0.410	0.000
S52.9 Fracture of forearm, part unspecified	0.590	0.410	0.000
S52.8 Fracture of other parts of forearm	0.590	0.410	0.000
S52.7 Multiple fractures of forearm	0.590	0.410	0.000
S52.4 Fracture of shafts of both ulna and radius	0.590	0.410	0.000
S52.3 Fracture of shaft of radius	0.590	0.410	0.000
S52.2 Fracture of shaft of ulna	0.590	0.410	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.589	0.411	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.588	0.412	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.588	0.412	0.000
C16 Malignant neoplasm of stomach	0.588	0.412	0.000
T92 Sequelae of injuries of upper limb	0.588	0.412	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.587	0.413	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.586	0.414	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.586	0.414	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.586	0.414	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.585	0.415	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.585	0.415	0.000
S60.2 Contusion of other parts of wrist and hand	0.585	0.415	0.000
S60.1 Contusion of finger(s) with damage to nail	0.585	0.415	0.000
S60.0 Contusion of finger(s) without damage to nail	0.585	0.415	0.000
T65 Toxic effect of other and unspecified substances	0.585	0.415	0.000
T62 Toxic effect of other noxious substances eaten as food	0.585	0.415	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.585	0.415	0.000
T60 Toxic effect of pesticides	0.585	0.415	0.000
T57 Toxic effect of other inorganic substances	0.585	0.415	0.000
T56 Toxic effect of metals	0.585	0.415	0.000
T54 Toxic effect of corrosive substances	0.585	0.415	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.585	0.415	0.000
T52 Toxic effect of organic solvents	0.585	0.415	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.585	0.415	0.000
T58 Toxic effect of carbon monoxide	0.585	0.415	0.000
T55 Toxic effect of soaps and detergents	0.585	0.415	0.000
N17 Acute renal failure	0.585	0.415	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.584	0.416	0.000
C44.8 Overlapping lesion of skin	0.584	0.416	0.000
G90 Disorders of autonomic nervous system	0.583	0.416	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.583	0.416	0.000
T87 Complications peculiar to reattachment and amputation	0.583	0.417	0.000
T86 Failure and rejection of transplanted organs and tissues	0.583	0.417	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.583	0.417	0.000
C18.7 Sigmoid colon	0.583	0.417	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.583	0.417	0.000
G91 Hydrocephalus	0.583	0.417	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.582	0.417	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.582	0.418	0.000
E28 Ovarian dysfunction	0.582	0.418	0.000
W29 Contact with other powered hand tools and household machinery	0.581	0.419	0.000
T93 Sequelae of injuries of lower limb	0.581	0.419	0.000
W06 Fall involving bed	0.581	0.419	0.000
S61.1 Open wound of finger(s) with damage to nail	0.581	0.419	0.000
C51-C58 Malignant neoplasms of female genital organs	0.580	0.420	0.000
I84.6 Residual haemorrhoidal skin tags	0.580	0.420	0.000
S22.3 Fracture of rib	0.578	0.421	0.000
E11 Non-insulin-dependent diabetes mellitus	0.578	0.422	0.000
C18.5 Splenic flexure	0.578	0.422	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.578	0.422	0.000
A04.8 Other specified bacterial intestinal infections	0.578	0.422	0.000
H10-H13 Disorders of conjunctiva	0.578	0.422	0.000
E66 Obesity	0.577	0.423	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.575	0.425	0.000
I78 Diseases of capillaries	0.575	0.425	0.000
S61.7 Multiple open wounds of wrist and hand	0.575	0.425	0.000
I60 Subarachnoid haemorrhage	0.574	0.426	0.000
Q27 Other congenital malformations of peripheral vascular system	0.573	0.427	0.000
B99-B99 Other infectious diseases	0.573	0.427	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.573	0.427	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.573	0.427	0.000
B50-B64 Protozoal diseases	0.573	0.427	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.573	0.427	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.573	0.427	0.000
A80-A89 Viral infections of the central nervous system	0.573	0.427	0.000
A75-A79 Rickettsioses	0.573	0.427	0.000
A70-A74 Other diseases caused by chlamydiae	0.573	0.427	0.000
A65-A69 Other spirochaetal diseases	0.573	0.427	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.573	0.427	0.000
A20-A28 Certain zoonotic bacterial diseases	0.573	0.427	0.000
A15-A19 Tuberculosis	0.573	0.427	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.572	0.427	0.000
F38 Other mood [affective] disorders	0.572	0.428	0.000
F34 Persistent mood [affective] disorders	0.572	0.428	0.000
F39 Unspecified mood [affective] disorder	0.572	0.428	0.000
I62 Other nontraumatic intracranial haemorrhage	0.572	0.428	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.571	0.428	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.571	0.428	0.000
C32 Malignant neoplasm of larynx	0.571	0.428	0.000
C31 Malignant neoplasm of accessory sinuses	0.571	0.428	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.571	0.428	0.000
C37 Malignant neoplasm of thymus	0.571	0.428	0.000
C33 Malignant neoplasm of trachea	0.571	0.428	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.572	0.428	0.000
F31.9 Bipolar affective disorder, unspecified	0.571	0.429	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.568	0.432	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.568	0.432	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.568	0.432	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.568	0.432	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.568	0.432	0.000
I71.0 Dissection of aorta [any part]	0.568	0.432	0.000
C50 Malignant neoplasm of breast	0.568	0.432	0.000
S61.0 Open wound of finger(s) without damage to nail	0.567	0.433	0.000
E07.8 Other specified disorders of thyroid	0.567	0.433	0.000
E07.1 Dyshormogenetic goitre	0.567	0.433	0.000
E07.0 Hypersecretion of calcitonin	0.567	0.433	0.000
F20 Schizophrenia	0.567	0.433	0.000
W18 Other fall on same level	0.566	0.434	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.566	0.434	0.000
W15 Fall from cliff	0.566	0.434	0.000
W14 Fall from tree	0.566	0.434	0.000
W12 Fall on and from scaffolding	0.566	0.434	0.000
W11 Fall on and from ladder	0.566	0.434	0.000
W09 Fall involving playground equipment	0.566	0.434	0.000
W08 Fall involving other furniture	0.566	0.434	0.000
W05 Fall involving wheelchair	0.566	0.434	0.000
W04 Fall while being carried or supported by other persons	0.566	0.434	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.566	0.434	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.566	0.434	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.566	0.434	0.000
W00 Fall on same level involving ice and snow	0.566	0.434	0.000
Q21.1 Atrial septal defect	0.566	0.434	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.566	0.434	0.000
B95-B98 Bacterial, viral and other infectious agents	0.566	0.434	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.565	0.435	0.000
I26 Pulmonary embolism	0.565	0.435	0.000
I22 Subsequent myocardial infarction	0.564	0.436	0.000
T75 Effects of other external causes	0.563	0.436	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations