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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72745135
log Bayes Factor = 15.0573
Chromosome 9   position 78,973,431  (GRCh37) Explore rs72745135 on Ensembl!
Variant rs72745135 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
C79 Secondary malignant neoplasm of other sites
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
I20-I25 Ischaemic heart diseases
0.978 0.022 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.977 0.023 0.000
T81 Complications of procedures, not elsewhere classified
0.973 0.027 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.973 0.027 0.000
S80-S89 Injuries to the knee and lower leg
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.969 0.031 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.960 0.040 0.000
M05-M14 Inflammatory polyarthropathies
0.957 0.043 0.000
Z51 Other medical care
0.957 0.043 0.000
I25 Chronic ischaemic heart disease
0.954 0.046 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.952 0.048 0.000
E11.9 Without complications
0.946 0.054 0.000
E70-E90 Metabolic disorders
0.945 0.055 0.000
M06 Other rheumatoid arthritis
0.944 0.056 0.000
Z43 Attention to artificial openings
0.940 0.060 0.000
S82 Fracture of lower leg, including ankle
0.937 0.063 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.934 0.066 0.000
M06.9 Rheumatoid arthritis, unspecified
0.932 0.068 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.932 0.068 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.930 0.070 0.000
I25.1 Atherosclerotic heart disease
0.927 0.073 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.927 0.073 0.000
I20 Angina pectoris
0.925 0.075 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.921 0.079 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.920 0.080 0.000
S82.8 Fractures of other parts of lower leg
0.917 0.083 0.000
Z51.0 Radiotherapy session
0.917 0.083 0.000
Z95.1 Presence of aortocoronary bypass graft
0.912 0.088 0.000
Z87 Personal history of other diseases and conditions
0.909 0.091 0.000
C64-C68 Malignant neoplasms of urinary tract
0.907 0.093 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.906 0.094 0.000
R30-R39 Symptoms and signs involving the urinary system
0.905 0.095 0.000
M50-M54 Other dorsopathies
0.904 0.096 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.904 0.096 0.000
E10 Insulin-dependent diabetes mellitus
0.902 0.098 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.900 0.100 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.899 0.101 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.898 0.102 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.897 0.103 0.000
Chapter XIV Diseases of the genitourinary system
0.896 0.104 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.892 0.108 0.000
Z85 Personal history of malignant neoplasm
0.889 0.111 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.888 0.112 0.000
Z87.0 Personal history of diseases of the respiratory system
0.887 0.113 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.886 0.114 0.000
Chapter I Certain infectious and parasitic diseases
0.886 0.114 0.000
Z95.4 Presence of other heart-valve replacement
0.885 0.115 0.000
S40-S49 Injuries to the shoulder and upper arm
0.884 0.116 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.884 0.116 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.881 0.119 0.000
Z93 Artificial opening status
0.872 0.128 0.000
Y83.8 Other surgical procedures
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.871 0.129 0.000
D00-D09 In situ neoplasms
0.867 0.133 0.000
Z51.8 Other specified medical care
0.866 0.134 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.864 0.136 0.000
R32 Unspecified urinary incontinence
0.860 0.140 0.000
E11.5 With peripheral circulatory complications
0.860 0.140 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.859 0.141 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.858 0.142 0.000
C78.7 Secondary malignant neoplasm of liver
0.858 0.142 0.000
I24 Other acute ischaemic heart diseases
0.857 0.143 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.854 0.146 0.000
Chapter XI Diseases of the digestive system
0.852 0.148 0.000
C77.3 Axillary and upper limb lymph nodes
0.852 0.148 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.850 0.150 0.000
R31 Unspecified haematuria
0.847 0.153 0.000
R50-R69 General symptoms and signs
0.846 0.154 0.000
N20-N23 Urolithiasis
0.843 0.157 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.833 0.167 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.831 0.169 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.831 0.169 0.000
Z95.2 Presence of prosthetic heart valve
0.831 0.169 0.000
N00-N08 Glomerular diseases
0.830 0.170 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.830 0.170 0.000
M45-M49 Spondylopathies
0.828 0.172 0.000
Z43.1 Attention to gastrostomy
0.827 0.173 0.000
Chapter V Mental and behavioural disorders
0.826 0.174 0.000
Chapter VI Diseases of the nervous system
0.823 0.177 0.000
C80 Malignant neoplasm without specification of site
0.821 0.179 0.000
R47-R49 Symptoms and signs involving speech and voice
0.819 0.181 0.000
Z43.2 Attention to ileostomy
0.818 0.182 0.000
A30-A49 Other bacterial diseases
0.816 0.184 0.000
Z90.7 Acquired absence of genital organ(s)
0.815 0.185 0.000
E10.9 Without complications
0.812 0.188 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.811 0.189 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.809 0.191 0.000
Y95 Nosocomial condition
0.809 0.191 0.000
C78.2 Secondary malignant neoplasm of pleura
0.808 0.192 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.807 0.193 0.000
Z49 Care involving dialysis
0.806 0.194 0.000
Y43 Primarily systemic agents
0.805 0.195 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.805 0.195 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.195 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.804 0.196 0.000
I20.0 Unstable angina
0.804 0.196 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.803 0.197 0.000
M54 Dorsalgia
0.803 0.197 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.803 0.197 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.802 0.198 0.000
Z51.1 Chemotherapy session for neoplasm
0.801 0.199 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.799 0.201 0.000
S42 Fracture of shoulder and upper arm
0.799 0.201 0.000
Z51.3 Blood transfusion without reported diagnosis
0.799 0.201 0.000
N10-N16 Renal tubulo-interstitial diseases
0.799 0.201 0.000
K90-K93 Other diseases of the digestive system
0.798 0.202 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.797 0.203 0.000
E11.2 With renal complications
0.797 0.203 0.000
M51 Other intervertebral disk disorders
0.797 0.203 0.000
Z97 Presence of other devices
0.796 0.204 0.000
E00-E07 Disorders of thyroid gland
0.796 0.204 0.000
W00-W19 Falls
0.795 0.205 0.000
Y52 Agents primarily affecting the cardiovascular system
0.795 0.205 0.000
S81 Open wound of lower leg
0.794 0.206 0.000
T66-T78 Other and unspecified effects of external causes
0.789 0.211 0.000
N17-N19 Renal failure
0.788 0.212 0.000
Z52 Donors of organs and tissues
0.786 0.214 0.000
V80-V89 Other land transport accidents
0.785 0.215 0.000
Z43.3 Attention to colostomy
0.785 0.215 0.000
Z89 Acquired absence of limb
0.784 0.216 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.784 0.216 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.784 0.216 0.000
M40-M43 Deforming dorsopathies
0.783 0.217 0.000
S00-S09 Injuries to the head
0.782 0.218 0.000
I22 Subsequent myocardial infarction
0.782 0.218 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.782 0.218 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.781 0.219 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.781 0.219 0.000
V10-V19 Pedal cyclist injured in transport accident
0.780 0.220 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.779 0.221 0.000
E86 Volume depletion
0.779 0.221 0.000
D50-D53 Nutritional anaemias
0.779 0.221 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.778 0.222 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.778 0.222 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.777 0.223 0.000
S10-S19 Injuries to the neck
0.777 0.223 0.000
V20-V29 Motorcycle rider injured in transport accident
0.776 0.224 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.776 0.224 0.000
I20.8 Other forms of angina pectoris
0.775 0.225 0.000
Z94 Transplanted organ and tissue status
0.775 0.225 0.000
K02 Dental caries
0.770 0.230 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.770 0.230 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.768 0.232 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.768 0.232 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.767 0.233 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.766 0.234 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.763 0.237 0.000
E13 Other specified diabetes mellitus
0.762 0.238 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.761 0.239 0.000
Z45 Adjustment and management of implanted device
0.760 0.240 0.000
C78.0 Secondary malignant neoplasm of lung
0.759 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.759 0.241 0.000
N23 Unspecified renal colic
0.758 0.242 0.000
E87.5 Hyperkalaemia
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.752 0.247 0.000
K04 Diseases of pulp and periapical tissues
0.752 0.248 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.750 0.250 0.000
C79.2 Secondary malignant neoplasm of skin
0.749 0.251 0.000
A41 Other septicaemia
0.749 0.251 0.000
C77.2 Intra-abdominal lymph nodes
0.747 0.253 0.000
Z85.6 Personal history of leukaemia
0.745 0.255 0.000
M05 Seropositive rheumatoid arthritis
0.744 0.256 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.742 0.258 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.742 0.258 0.000
C67 Malignant neoplasm of bladder
0.741 0.259 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.741 0.259 0.000
N20 Calculus of kidney and ureter
0.740 0.260 0.000
S82.6 Fracture of lateral malleolus
0.739 0.261 0.000
D50 Iron deficiency anaemia
0.739 0.261 0.000
E88 Other metabolic disorders
0.737 0.263 0.000
M80-M85 Disorders of bone density and structure
0.734 0.266 0.000
Z46 Fitting and adjustment of other devices
0.734 0.266 0.000
I20.1 Angina pectoris with documented spasm
0.733 0.267 0.000
Y57 Other and unspecified drugs and medicaments
0.732 0.268 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.731 0.269 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.730 0.270 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.730 0.270 0.000
C15-C26 Malignant neoplasms of digestive organs
0.729 0.271 0.000
I71 Aortic aneurysm and dissection
0.728 0.272 0.000
M06.0 Seronegative rheumatoid arthritis
0.728 0.272 0.000
I20.9 Angina pectoris, unspecified
0.727 0.273 0.000
D06 Carcinoma in situ of cervix uteri
0.726 0.274 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.726 0.274 0.000
E20-E35 Disorders of other endocrine glands
0.726 0.274 0.000
S20-S29 Injuries to the thorax
0.725 0.275 0.000
K02.9 Dental caries, unspecified
0.725 0.275 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.725 0.275 0.000
E10.4 With neurological complications
0.724 0.276 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.722 0.278 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.721 0.279 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.720 0.280 0.000
C51-C58 Malignant neoplasms of female genital organs
0.719 0.281 0.000
R52 Pain, not elsewhere classified
0.719 0.281 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.718 0.282 0.000
Y43.3 Other antineoplastic drugs
0.718 0.282 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.718 0.282 0.000
S80 Superficial injury of lower leg
0.718 0.282 0.000
C92 Myeloid leukaemia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T91 Sequelae of injuries of neck and trunk
0.717 0.283 0.000
M54.2 Cervicalgia
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X60-X84 Intentional self-harm
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.715 0.285 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.714 0.286 0.000
M51.2 Other specified intervertebral disk displacement
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.713 0.287 0.000
C50-C50 Malignant neoplasm of breast
0.712 0.288 0.000
Chapter X Diseases of the respiratory system
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.288 0.000
I05-I09 Chronic rheumatic heart diseases
0.711 0.289 0.000
K82 Other diseases of gallbladder
0.711 0.289 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
I25.5 Ischaemic cardiomyopathy
0.709 0.291 0.000
Y40 Systemic antibiotics
0.708 0.292 0.000
C79.6 Secondary malignant neoplasm of ovary
0.708 0.292 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.708 0.292 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.708 0.292 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.708 0.292 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.708 0.292 0.000
K86 Other diseases of pancreas
0.708 0.292 0.000
Z93.2 Ileostomy status
0.708 0.292 0.000
M86-M90 Other osteopathies
0.707 0.293 0.000
Z90.3 Acquired absence of part of stomach
0.707 0.293 0.000
O60-O75 Complications of labour and delivery
0.705 0.295 0.000
M11 Other crystal arthropathies
0.704 0.296 0.000
T90 Sequelae of injuries of head
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.703 0.297 0.000
Y83.6 Removal of other organ (partial) (total)
0.703 0.297 0.000
K01 Embedded and impacted teeth
0.702 0.298 0.000
Z92 Personal history of medical treatment
0.702 0.298 0.000
I60-I69 Cerebrovascular diseases
0.702 0.298 0.000
Z54 Convalescence
0.702 0.298 0.000
Z44 Fitting and adjustment of external prosthetic device
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
M91-M94 Chondropathies
0.702 0.298 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.702 0.298 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.701 0.299 0.000
I23 Certain current complications following acute myocardial infarction
0.701 0.299 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.700 0.299 0.000
Z95.3 Presence of xenogenic heart valve
0.700 0.299 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.301 0.000
A41.9 Septicaemia, unspecified
0.698 0.302 0.000
T81.9 Unspecified complication of procedure
0.698 0.302 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.698 0.302 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.698 0.302 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.698 0.302 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.698 0.302 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.697 0.302 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.697 0.302 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.697 0.302 0.000
K91.4 Colostomy and enterostomy malfunction
0.697 0.303 0.000
S89 Other and unspecified injuries of lower leg
0.697 0.303 0.000
S88 Traumatic amputation of lower leg
0.697 0.303 0.000
S87 Crushing injury of lower leg
0.697 0.303 0.000
S86 Injury of muscle and tendon at lower leg level
0.697 0.303 0.000
S85 Injury of blood vessels at lower leg level
0.697 0.303 0.000
S84 Injury of nerves at lower leg level
0.697 0.303 0.000
R87 Abnormal findings in specimens from female genital organs
0.697 0.303 0.000
G30-G32 Other degenerative diseases of the nervous system
0.697 0.303 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.696 0.304 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.695 0.305 0.000
E11.8 With unspecified complications
0.694 0.306 0.000
E11.7 With multiple complications
0.694 0.306 0.000
E11.6 With other specified complications
0.694 0.306 0.000
E11.1 With ketoacidosis
0.694 0.306 0.000
E11.0 With coma
0.694 0.306 0.000
M54.9 Dorsalgia, unspecified
0.694 0.306 0.000
G90-G99 Other disorders of the nervous system
0.694 0.306 0.000
M47 Spondylosis
0.692 0.308 0.000
Y83.9 Surgical procedure, unspecified
0.691 0.309 0.000
D03 Melanoma in situ
0.691 0.309 0.000
R33 Retention of urine
0.691 0.309 0.000
C90.0 Multiple myeloma
0.691 0.309 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.690 0.310 0.000
C77.8 Lymph nodes of multiple regions
0.690 0.310 0.000
Y83.3 Surgical operation with formation of external stoma
0.690 0.310 0.000
Z40 Prophylactic surgery
0.688 0.312 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
K04.7 Periapical abscess without sinus
0.686 0.313 0.000
M14 Arthropathies in other diseases classified elsewhere
0.686 0.314 0.000
M12 Other specific arthropathies
0.686 0.314 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.686 0.314 0.000
M08 Juvenile arthritis
0.686 0.314 0.000
M07 Psoriatic and enteropathic arthropathies
0.686 0.314 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.686 0.314 0.000
Z51.9 Medical care, unspecified
0.686 0.314 0.000
Z51.6 Desensitisation to allergens
0.686 0.314 0.000
R49 Voice disturbances
0.686 0.314 0.000
I25.6 Silent myocardial ischaemia
0.684 0.316 0.000
I25.4 Coronary artery aneurysm
0.684 0.316 0.000
I25.3 Aneurysm of heart
0.684 0.316 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.684 0.316 0.000
D04 Carcinoma in situ of skin
0.683 0.317 0.000
N99-N99 Other disorders of the genitourinary system
0.683 0.317 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.683 0.317 0.000
Chapter VII Diseases of the eye and adnexa
0.681 0.319 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.681 0.319 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.680 0.320 0.000
N19 Unspecified renal failure
0.680 0.320 0.000
R51 Headache
0.680 0.320 0.000
R55 Syncope and collapse
0.680 0.320 0.000
Z90.1 Acquired absence of breast(s)
0.679 0.321 0.000
Y44 Agents primarily affecting blood constituents
0.678 0.321 0.000
D50.9 Iron deficiency anaemia, unspecified
0.678 0.322 0.000
E85 Amyloidosis
0.677 0.323 0.000
E84 Cystic fibrosis
0.677 0.323 0.000
E79 Disorders of purine and pyrimidine metabolism
0.677 0.323 0.000
E77 Disorders of glycoprotein metabolism
0.677 0.323 0.000
E76 Disorders of glycosaminoglycan metabolism
0.677 0.323 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.677 0.323 0.000
E74 Other disorders of carbohydrate metabolism
0.677 0.323 0.000
E73 Lactose intolerance
0.677 0.323 0.000
E72 Other disorders of amino-acid metabolism
0.677 0.323 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.677 0.323 0.000
E70 Disorders of aromatic amino-acid metabolism
0.677 0.323 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.677 0.323 0.000
M06.8 Other specified rheumatoid arthritis
0.677 0.323 0.000
M06.4 Inflammatory polyarthropathy
0.677 0.323 0.000
M06.3 Rheumatoid nodule
0.677 0.323 0.000
M06.2 Rheumatoid bursitis
0.677 0.323 0.000
M06.1 Adult-onset Still's disease
0.677 0.323 0.000
E87.6 Hypokalaemia
0.676 0.324 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.675 0.325 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.674 0.326 0.000
E05.9 Thyrotoxicosis, unspecified
0.674 0.326 0.000
Z43.9 Attention to unspecified artificial opening
0.674 0.326 0.000
Z43.8 Attention to other artificial openings
0.674 0.326 0.000
Z43.7 Attention to artificial vagina
0.674 0.326 0.000
Z43.5 Attention to cyctostomy
0.674 0.326 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.674 0.326 0.000
Z43.0 Attention to tracheostomy
0.674 0.326 0.000
R60 Oedema, not elsewhere classified
0.672 0.328 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.672 0.328 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.672 0.328 0.000
S82.9 Fracture of lower leg, part unspecified
0.671 0.328 0.000
S82.7 Multiple fractures of lower leg
0.671 0.328 0.000
S82.0 Fracture of patella
0.671 0.328 0.000
E10.3 With ophthalmic complications
0.671 0.328 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.671 0.329 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.671 0.329 0.000
G20-G26 Extrapyramidal and movement disorders
0.669 0.331 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.668 0.332 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.668 0.332 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.668 0.332 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.668 0.332 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.668 0.332 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.668 0.332 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.668 0.332 0.000
M10 Gout
0.667 0.333 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.667 0.333 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.667 0.333 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.667 0.333 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.667 0.333 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.666 0.334 0.000
Y59 Other and unspecified vaccines and biological substances
0.665 0.335 0.000
Y58 Bacterial vaccines
0.665 0.335 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.665 0.335 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.665 0.335 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.665 0.335 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.665 0.335 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
Y48 Anaesthetics and therapeutic gases
0.665 0.335 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.665 0.335 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.665 0.335 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
C01 Malignant neoplasm of base of tongue
0.665 0.335 0.000
Z93.1 Gastrostomy status
0.664 0.336 0.000
O80-O84 Delivery
0.664 0.336 0.000
C60-C63 Malignant neoplasms of male genital organs
0.663 0.337 0.000
E14 Unspecified diabetes mellitus
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.661 0.339 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.660 0.340 0.000
E87.4 Mixed disorder of acid-base balance
0.660 0.340 0.000
E87.3 Alkalosis
0.660 0.340 0.000
S42.3 Fracture of shaft of humerus
0.660 0.340 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.660 0.340 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.660 0.340 0.000
R56 Convulsions, not elsewhere classified
0.659 0.341 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.659 0.341 0.000
N17 Acute renal failure
0.659 0.341 0.000
C81 Hodgkin's disease
0.659 0.341 0.000
C80.9 Malignant neoplasm, unspecified
0.658 0.342 0.000
S82.86 Maisonneuve's fracture
0.658 0.342 0.000
S82.81 Fractures of other parts of lower leg (open)
0.658 0.342 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.658 0.342 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.657 0.343 0.000
D80-D89 Certain disorders involving the immune mechanism
0.656 0.344 0.000
Z29 Need for other prophylactic measures
0.655 0.345 0.000
Z41 Procedures for purposes other than remedying health state
0.655 0.345 0.000
T93 Sequelae of injuries of lower limb
0.655 0.345 0.000
E87.2 Acidosis
0.654 0.346 0.000
K08 Other disorders of teeth and supporting structures
0.652 0.348 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.652 0.348 0.000
Z93.5 Cystostomy status
0.652 0.348 0.000
E87.7 Fluid overload
0.652 0.348 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.652 0.348 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.652 0.348 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.652 0.348 0.000
Z87.8 Personal history of other specified conditions
0.651 0.348 0.000
I72 Other aneurysm
0.650 0.349 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.650 0.349 0.000
C66 Malignant neoplasm of ureter
0.650 0.349 0.000
C65 Malignant neoplasm of renal pelvis
0.650 0.349 0.000
S82.4 Fracture of fibula alone
0.650 0.350 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.650 0.350 0.000
Z49.1 Extracorporeal dialysis
0.650 0.350 0.000
Z90.8 Acquired absence of other organs
0.650 0.350 0.000
Z90.0 Acquired absence of part of head and neck
0.650 0.350 0.000
R61 Hyperhidrosis
0.649 0.350 0.000
R36 Urethral discharge
0.649 0.351 0.000
R34 Anuria and oliguria
0.649 0.351 0.000
S42.1 Fracture of scapula
0.649 0.351 0.000
S82.5 Fracture of medial malleolus
0.648 0.351 0.000
M53 Other dorsopathies, not elsewhere classified
0.648 0.352 0.000
Z90.2 Acquired absence of lung [part of]
0.648 0.352 0.000
Z52.4 Kidney donor
0.648 0.352 0.000
S91 Open wound of ankle and foot
0.647 0.353 0.000
E10.8 With unspecified complications
0.647 0.353 0.000
E10.7 With multiple complications
0.647 0.353 0.000
E10.6 With other specified complications
0.647 0.353 0.000
E10.5 With peripheral circulatory complications
0.647 0.353 0.000
E10.2 With renal complications
0.647 0.353 0.000
E10.0 With coma
0.647 0.353 0.000
A49 Bacterial infection of unspecified site
0.647 0.353 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.646 0.354 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.646 0.354 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.645 0.354 0.000
C95 Leukaemia of unspecified cell type
0.645 0.354 0.000
C94 Other leukaemias of specified cell type
0.645 0.354 0.000
C93 Monocytic leukaemia
0.645 0.354 0.000
C88 Malignant immunoproliferative diseases
0.645 0.354 0.000
C86 Other specified types of T/NK-cell lymphoma
0.645 0.354 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.645 0.354 0.000
K05 Gingivitis and periodontal diseases
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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