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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72952568
log Bayes Factor = 24.7996
Chromosome 6   position 114,493,211  (GRCh37) Explore rs72952568 on Ensembl!
Variant rs72952568 is part of Cluster X0248

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
F32 Depressive episode
1.000 0.000 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
F32.9 Depressive episode, unspecified
1.000 0.000 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.999 0.001 0.000
D12.8 Rectum
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
R11 Nausea and vomiting
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
R10 Abdominal and pelvic pain
0.994 0.006 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.993 0.007 0.000
R69 Unknown and unspecified causes of morbidity
0.993 0.007 0.000
K55-K64 Other diseases of intestines
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
O70 Perineal laceration during delivery
0.990 0.010 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.985 0.015 0.000
F10.0 Acute intoxication
0.983 0.017 0.000
K63 Other diseases of intestine
0.972 0.028 0.000
O70.1 Second degree perineal laceration during delivery
0.971 0.029 0.000
Chapter X Diseases of the respiratory system
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
F31 Bipolar affective disorder
0.966 0.034 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.966 0.034 0.000
R10.3 Pain localised to other parts of lower abdomen
0.962 0.038 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.961 0.039 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.952 0.048 0.000
D12.3 Transverse colon
0.949 0.051 0.000
D12.0 Caecum
0.946 0.054 0.000
K29 Gastritis and duodenitis
0.939 0.061 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.939 0.061 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.936 0.064 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.936 0.064 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.928 0.072 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.925 0.075 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.924 0.076 0.000
K62 Other diseases of anus and rectum
0.924 0.076 0.000
F31.9 Bipolar affective disorder, unspecified
0.920 0.080 0.000
K58 Irritable bowel syndrome
0.916 0.084 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
R60 Oedema, not elsewhere classified
0.912 0.088 0.000
K29.5 Chronic gastritis, unspecified
0.911 0.089 0.000
K63.5 Polyp of colon
0.908 0.092 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.907 0.093 0.000
R51 Headache
0.907 0.093 0.000
K63.9 Disease of intestine, unspecified
0.903 0.097 0.000
G90-G99 Other disorders of the nervous system
0.902 0.098 0.000
Chapter VIII Diseases of the ear and mastoid process
0.898 0.102 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.896 0.104 0.000
R10.2 Pelvic and perineal pain
0.893 0.106 0.000
F41 Other anxiety disorders
0.891 0.109 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.891 0.109 0.000
F10.1 Harmful use
0.889 0.111 0.000
O70.0 First degree perineal laceration during delivery
0.888 0.112 0.000
K62.1 Rectal polyp
0.887 0.113 0.000
R10.4 Other and unspecified abdominal pain
0.884 0.116 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.883 0.117 0.000
O42 Premature rupture of membranes
0.879 0.121 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.877 0.123 0.000
F10.2 Dependence syndrome
0.877 0.123 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.875 0.125 0.000
K20 Oesophagitis
0.867 0.133 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.867 0.133 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.865 0.135 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.859 0.141 0.000
Chapter I Certain infectious and parasitic diseases
0.853 0.147 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.852 0.148 0.000
J90-J94 Other diseases of pleura
0.848 0.152 0.000
D27 Benign neoplasm of ovary
0.848 0.152 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.844 0.156 0.000
M75 Shoulder lesions
0.844 0.156 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.843 0.157 0.000
F33 Recurrent depressive disorder
0.838 0.162 0.000
X60-X84 Intentional self-harm
0.837 0.163 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.836 0.164 0.000
D17 Benign lipomatous neoplasm
0.834 0.166 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.834 0.166 0.000
M05-M14 Inflammatory polyarthropathies
0.833 0.167 0.000
H65-H75 Diseases of middle ear and mastoid
0.832 0.168 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.832 0.168 0.000
D12.2 Ascending colon
0.830 0.170 0.000
G57 Mononeuropathies of lower limb
0.830 0.170 0.000
K29.7 Gastritis, unspecified
0.828 0.172 0.000
S80 Superficial injury of lower leg
0.828 0.172 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.827 0.173 0.000
J09-J18 Influenza and pneumonia
0.827 0.173 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.826 0.174 0.000
R94 Abnormal results of function studies
0.826 0.174 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.826 0.174 0.000
T39.1 4-Aminophenol derivatives
0.825 0.175 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.825 0.175 0.000
K63.4 Enteroptosis
0.823 0.177 0.000
W00-W19 Falls
0.822 0.178 0.000
R60.0 Localised oedema
0.821 0.179 0.000
F43 Reaction to severe stress, and adjustment disorders
0.820 0.180 0.000
O66 Other obstructed labour
0.819 0.181 0.000
T81 Complications of procedures, not elsewhere classified
0.819 0.181 0.000
M72 Fibroblastic disorders
0.817 0.183 0.000
J20-J22 Other acute lower respiratory infections
0.817 0.183 0.000
M75.4 Impingement syndrome of shoulder
0.814 0.186 0.000
K86 Other diseases of pancreas
0.814 0.186 0.000
K55 Vascular disorders of intestine
0.813 0.187 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.812 0.188 0.000
C15-C26 Malignant neoplasms of digestive organs
0.802 0.198 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.801 0.199 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.800 0.200 0.000
D12.4 Descending colon
0.799 0.201 0.000
S20-S29 Injuries to the thorax
0.799 0.201 0.000
T86 Failure and rejection of transplanted organs and tissues
0.798 0.202 0.000
Chapter IX Diseases of the circulatory system
0.797 0.203 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.797 0.203 0.000
F30 Manic episode
0.796 0.204 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.796 0.204 0.000
S50-S59 Injuries to the elbow and forearm
0.794 0.206 0.000
F17.1 Harmful use
0.791 0.209 0.000
F60-F69 Disorders of adult personality and behaviour
0.791 0.209 0.000
F41.9 Anxiety disorder, unspecified
0.790 0.210 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.786 0.214 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.214 0.000
F41.2 Mixed anxiety and depressive disorder
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
D46 Myelodysplastic syndromes
0.784 0.215 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.780 0.220 0.000
O42.9 Premature rupture of membranes, unspecified
0.780 0.220 0.000
K61 Abscess of anal and rectal regions
0.779 0.221 0.000
O62 Abnormalities of forces of labour
0.779 0.221 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.778 0.222 0.000
K62.8 Other specified diseases of anus and rectum
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.776 0.224 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.775 0.225 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.226 0.000
K29.1 Other acute gastritis
0.773 0.227 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.773 0.227 0.000
O63 Long labour
0.773 0.227 0.000
M20-M25 Other joint disorders
0.773 0.227 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.772 0.228 0.000
R10.0 Acute abdomen
0.771 0.229 0.000
R57 Shock, not elsewhere classified
0.771 0.229 0.000
D45 Polycythaemia vera
0.770 0.230 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.770 0.230 0.000
D12.6 Colon, unspecified
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.769 0.231 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.768 0.232 0.000
G81 Hemiplegia
0.767 0.233 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.765 0.235 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.764 0.236 0.000
G35 Multiple sclerosis
0.764 0.236 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.761 0.239 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.761 0.239 0.000
T66-T78 Other and unspecified effects of external causes
0.760 0.240 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.758 0.242 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.757 0.243 0.000
F45 Somatoform disorders
0.757 0.243 0.000
S00-S09 Injuries to the head
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
R94.5 Abnormal results of liver function studies
0.756 0.244 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.754 0.246 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.754 0.246 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.754 0.246 0.000
K63.8 Other specified diseases of intestine
0.753 0.247 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.753 0.247 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.753 0.247 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.752 0.248 0.000
G57.6 Lesion of plantar nerve
0.750 0.250 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.749 0.250 0.000
O73 Retained placenta and membranes, without haemorrhage
0.749 0.251 0.000
Y52 Agents primarily affecting the cardiovascular system
0.749 0.251 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.749 0.251 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
Y44 Agents primarily affecting blood constituents
0.748 0.252 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.747 0.253 0.000
D10 Benign neoplasm of mouth and pharynx
0.747 0.253 0.000
J91 Pleural effusion in conditions classified elsewhere
0.747 0.253 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.746 0.253 0.000
R60.9 Oedema, unspecified
0.744 0.256 0.000
S32 Fracture of lumbar spine and pelvis
0.744 0.256 0.000
H72 Perforation of tympanic membrane
0.744 0.256 0.000
D36 Benign neoplasm of other and unspecified sites
0.743 0.256 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.743 0.257 0.000
J00-J06 Acute upper respiratory infections
0.743 0.257 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.741 0.259 0.000
I30-I52 Other forms of heart disease
0.741 0.259 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.739 0.260 0.000
R63 Symptoms and signs concerning food and fluid intake
0.739 0.261 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.739 0.261 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.738 0.262 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.738 0.262 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.737 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
G70-G73 Diseases of myoneural junction and muscle
0.736 0.264 0.000
S89 Other and unspecified injuries of lower leg
0.736 0.264 0.000
K81 Cholecystitis
0.735 0.265 0.000
F03 Unspecified dementia
0.734 0.266 0.000
D34 Benign neoplasm of thyroid gland
0.734 0.266 0.000
G93 Other disorders of brain
0.734 0.266 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.734 0.266 0.000
J30-J39 Other diseases of upper respiratory tract
0.733 0.267 0.000
K70-K77 Diseases of liver
0.732 0.268 0.000
W20-W49 Exposure to inanimate mechanical forces
0.731 0.268 0.000
G58 Other mononeuropathies
0.730 0.270 0.000
G20-G26 Extrapyramidal and movement disorders
0.727 0.273 0.000
K60 Fissure and fistula of anal and rectal regions
0.727 0.273 0.000
M25 Other joint disorders, not elsewhere classified
0.727 0.273 0.000
J94 Other pleural conditions
0.725 0.275 0.000
J60-J70 Lung diseases due to external agents
0.725 0.275 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.723 0.277 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.723 0.277 0.000
D32 Benign neoplasm of meninges
0.723 0.277 0.000
K27 Peptic ulcer, site unspecified
0.722 0.278 0.000
M00-M03 Infectious arthropathies
0.722 0.278 0.000
O72 Postpartum haemorrhage
0.719 0.281 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
G96 Other disorders of central nervous system
0.717 0.283 0.000
K29.2 Alcoholic gastritis
0.717 0.283 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.717 0.283 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.717 0.283 0.000
I50 Heart failure
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
S82 Fracture of lower leg, including ankle
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
F32.8 Other depressive episodes
0.717 0.283 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.717 0.283 0.000
F32.0 Mild depressive episode
0.717 0.283 0.000
D12.9 Anus and anal canal
0.717 0.283 0.000
D12.1 Appendix
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.284 0.000
O61 Failed induction of labour
0.716 0.284 0.000
O60 Preterm delivery
0.716 0.284 0.000
Y45.0 Opioids and related analgesics
0.716 0.284 0.000
O70.2 Third degree perineal laceration during delivery
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.284 0.000
D30 Benign neoplasm of urinary organs
0.716 0.284 0.000
D29 Benign neoplasm of male genital organs
0.716 0.284 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.284 0.000
D26 Other benign neoplasms of uterus
0.716 0.284 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.715 0.285 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.714 0.286 0.000
K62.9 Disease of anus and rectum, unspecified
0.714 0.286 0.000
S31 Open wound of abdomen, lower back and pelvis
0.713 0.287 0.000
F10.9 Unspecified mental and behavioural disorder
0.713 0.287 0.000
F10.8 Other mental and behavioural disorders
0.713 0.287 0.000
F10.7 Residual and late-onset psychotic disorder
0.713 0.287 0.000
F10.6 Amnesic syndrome
0.713 0.287 0.000
F10.5 Psychotic disorder
0.713 0.287 0.000
F10.4 Withdrawal state with delirium
0.713 0.287 0.000
R68 Other general symptoms and signs
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.712 0.288 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.712 0.288 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.712 0.288 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.712 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.711 0.289 0.000
G91 Hydrocephalus
0.710 0.290 0.000
O70.9 Perineal laceration during delivery, unspecified
0.710 0.290 0.000
O70.3 Fourth degree perineal laceration during delivery
0.710 0.290 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.710 0.290 0.000
K29.0 Acute haemorrhagic gastritis
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.708 0.292 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.708 0.292 0.000
J22 Unspecified acute lower respiratory infection
0.708 0.292 0.000
D24 Benign neoplasm of breast
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
K65-K67 Diseases of peritoneum
0.706 0.294 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.704 0.295 0.000
C73 Malignant neoplasm of thyroid gland
0.704 0.296 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.702 0.298 0.000
B95-B98 Bacterial, viral and other infectious agents
0.701 0.299 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.700 0.299 0.000
F43.2 Adjustment disorders
0.700 0.300 0.000
O40 Polyhydramnios
0.700 0.300 0.000
S80.9 Superficial injury of lower leg, unspecified
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.699 0.301 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
G40-G47 Episodic and paroxysmal disorders
0.699 0.301 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.699 0.301 0.000
T79-T79 Certain early complications of trauma
0.698 0.302 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.698 0.302 0.000
M06 Other rheumatoid arthritis
0.698 0.302 0.000
T82.1 Mechanical complication of cardiac electronic device
0.697 0.303 0.000
K63.0 Abscess of intestine
0.697 0.303 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.697 0.303 0.000
K86.1 Other chronic pancreatitis
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.304 0.000
Y10-Y34 Event of undetermined intent
0.695 0.304 0.000
Y00-Y09 Assault
0.695 0.304 0.000
X85-X99 Assault
0.695 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.304 0.000
X50-X57 Overexertion, travel and privation
0.695 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.304 0.000
X30-X39 Exposure to forces of nature
0.695 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.304 0.000
X10-X19 Contact with heat and hot substances
0.695 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.304 0.000
W75-W84 Other accidental threats to breathing
0.695 0.304 0.000
W65-W74 Accidental drowning and submersion
0.695 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.304 0.000
V95-V97 Air and space transport accidents
0.695 0.304 0.000
V90-V94 Water transport accidents
0.695 0.304 0.000
V80-V89 Other land transport accidents
0.695 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.304 0.000
G81.9 Hemiplegia, unspecified
0.695 0.305 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.693 0.307 0.000
F31.8 Other bipolar affective disorders
0.693 0.307 0.000
F31.7 Bipolar affective disorder, currently in remission
0.693 0.307 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.693 0.307 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.693 0.307 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.693 0.307 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.693 0.307 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.693 0.307 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.693 0.307 0.000
M91-M94 Chondropathies
0.693 0.307 0.000
M60-M63 Disorders of muscles
0.693 0.307 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.307 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.693 0.307 0.000
T39.0 Salicylates
0.692 0.307 0.000
C16 Malignant neoplasm of stomach
0.691 0.309 0.000
D00-D09 In situ neoplasms
0.691 0.309 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.691 0.309 0.000
K55.2 Angiodysplasia of colon
0.690 0.310 0.000
F48 Other neurotic disorders
0.689 0.311 0.000
F44 Dissociative [conversion] disorders
0.689 0.311 0.000
F42 Obsessive-compulsive disorder
0.689 0.311 0.000
G30-G32 Other degenerative diseases of the nervous system
0.688 0.311 0.000
J92 Pleural plaque
0.688 0.312 0.000
O30 Multiple gestation
0.687 0.312 0.000
K29.6 Other gastritis
0.687 0.313 0.000
T42.4 Benzodiazepines
0.686 0.313 0.000
R47-R49 Symptoms and signs involving speech and voice
0.686 0.314 0.000
O75.8 Other specified complications of labour and delivery
0.686 0.314 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.685 0.314 0.000
H66 Suppurative and unspecified otitis media
0.685 0.315 0.000
K25 Gastric ulcer
0.685 0.315 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.685 0.315 0.000
M13 Other arthritis
0.684 0.316 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.683 0.316 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.683 0.317 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.683 0.317 0.000
K28 Gastrojejunal ulcer
0.683 0.317 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.683 0.317 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.683 0.317 0.000
O43 Placental disorders
0.683 0.317 0.000
R61 Hyperhidrosis
0.682 0.318 0.000
G51 Facial nerve disorders
0.682 0.318 0.000
F40 Phobic anxiety disorders
0.682 0.318 0.000
B35-B49 Mycoses
0.681 0.319 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.680 0.320 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.680 0.320 0.000
K86.8 Other specified diseases of pancreas
0.680 0.320 0.000
S80.0 Contusion of knee
0.679 0.321 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.678 0.322 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.677 0.323 0.000
T51 Toxic effect of alcohol
0.677 0.323 0.000
F32.1 Moderate depressive episode
0.677 0.323 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.677 0.323 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.677 0.323 0.000
M25.7 Osteophyte
0.675 0.325 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.675 0.325 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.674 0.325 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.674 0.326 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.674 0.326 0.000
M75.3 Calcific tendinitis of shoulder
0.674 0.326 0.000
K29.9 Gastroduodenitis, unspecified
0.673 0.327 0.000
K29.3 Chronic superficial gastritis
0.673 0.327 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.673 0.327 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.673 0.327 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.673 0.327 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.673 0.327 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.673 0.327 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.673 0.327 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.673 0.327 0.000
W06 Fall involving bed
0.673 0.327 0.000
X62.9 Unspecified place
0.673 0.327 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.672 0.328 0.000
M50-M54 Other dorsopathies
0.672 0.328 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.671 0.329 0.000
T50.8 Diagnostic agents
0.671 0.329 0.000
T50.7 Analeptics and opioid receptor antagonists
0.671 0.329 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.671 0.329 0.000
T50.5 Appetite depressants
0.671 0.329 0.000
T50.4 Drugs affecting uric acid metabolism
0.671 0.329 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.671 0.329 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.671 0.329 0.000
T50.1 Loop [high-ceiling] diuretics
0.671 0.329 0.000
T50.0 Mineralocorticoids and their antagonists
0.671 0.329 0.000
D11 Benign neoplasm of major salivary glands
0.671 0.329 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.671 0.329 0.000
R10.1 Pain localised to upper abdomen
0.671 0.329 0.000
K63.1 Perforation of intestine (nontraumatic)
0.670 0.329 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.669 0.331 0.000
R50 Fever of unknown origin
0.669 0.331 0.000
G57.1 Meralgia paraesthetica
0.666 0.334 0.000
J40-J47 Chronic lower respiratory diseases
0.666 0.334 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.665 0.335 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.335 0.000
T39.4 Antirheumatics, not elsewhere classified
0.665 0.335 0.000
T39.2 Pyrazolone derivatives
0.665 0.335 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.665 0.335 0.000
O47 False labour
0.665 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.335 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.335 0.000
M71 Other bursopathies
0.664 0.335 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.663 0.337 0.000
S88 Traumatic amputation of lower leg
0.663 0.337 0.000
S87 Crushing injury of lower leg
0.663 0.337 0.000
S86 Injury of muscle and tendon at lower leg level
0.663 0.337 0.000
S85 Injury of blood vessels at lower leg level
0.663 0.337 0.000
S84 Injury of nerves at lower leg level
0.663 0.337 0.000
I50.0 Congestive heart failure
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.337 0.000
Y45.2 Propionic acid derivatives
0.662 0.338 0.000
D12.7 Rectosigmoid junction
0.662 0.338 0.000
J14 Pneumonia due to Haemophilus influenzae
0.662 0.338 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.662 0.338 0.000
K62.2 Anal prolapse
0.662 0.338 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.661 0.339 0.000
J33 Nasal polyp
0.661 0.339 0.000
K56.2 Volvulus
0.661 0.339 0.000
K62.5 Haemorrhage of anus and rectum
0.660 0.340 0.000
M77 Other enthesopathies
0.660 0.340 0.000
V10-V19 Pedal cyclist injured in transport accident
0.658 0.342 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.656 0.344 0.000
F33.9 Recurrent depressive disorder, unspecified
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y57 Other and unspecified drugs and medicaments
0.656 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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