TreeWAS – Variant ID: rs73002470

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
M70-M79 Other soft tissue disorders	0.998	0.002
M20-M25 Other joint disorders	0.997	0.003
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.993	0.007
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.988	0.012
Chapter XV Pregnancy, childbirth and the puerperium	0.987	0.013
M79 Other soft tissue disorders, not elsewhere classified	0.986	0.014
Chapter VI Diseases of the nervous system	0.985	0.015
Chapter XIV Diseases of the genitourinary system	0.983	0.017
Chapter VIII Diseases of the ear and mastoid process	0.980	0.020
M25 Other joint disorders, not elsewhere classified	0.978	0.022
Chapter XX External causes of morbidity and mortality	0.977	0.023
N80-N98 Noninflammatory disorders of female genital tract	0.977	0.023
G50-G59 Nerve, nerve root and plexus disorders	0.974	0.026
M05-M14 Inflammatory polyarthropathies	0.966	0.034
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.961	0.039
S60-S69 Injuries to the wrist and hand	0.960	0.040
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.948	0.052
M75 Shoulder lesions	0.941	0.059
N93 Other abnormal uterine and vaginal bleeding	0.936	0.064
O60-O75 Complications of labour and delivery	0.935	0.065
H65-H75 Diseases of middle ear and mastoid	0.933	0.067
T84.0 Mechanical complication of internal joint prosthesis	0.930	0.070
N95 Menopausal and other perimenopausal disorders	0.922	0.078
M75.1 Rotator cuff syndrome	0.922	0.078
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.916	0.084
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.914	0.086
Chapter IX Diseases of the circulatory system	0.914	0.086
N40-N51 Diseases of male genital organs	0.911	0.089
N89 Other noninflammatory disorders of vagina	0.911	0.089
N95.0 Postmenopausal bleeding	0.908	0.092
D70-D77 Other diseases of blood and blood-forming organs	0.905	0.095
O72 Postpartum haemorrhage	0.898	0.102
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.897	0.103
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.896	0.104
Q60-Q64 Congenital malformations of the urinary system	0.894	0.106
I20-I25 Ischaemic heart diseases	0.892	0.108
O20-O29 Other maternal disorders predominantly related to pregnancy	0.891	0.109
M06 Other rheumatoid arthritis	0.891	0.109
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.889	0.111
M79.0 Rheumatism, unspecified	0.888	0.112
S20-S29 Injuries to the thorax	0.887	0.113
H60-H62 Diseases of external ear	0.886	0.114
N93.8 Other specified abnormal uterine and vaginal bleeding	0.885	0.115
O80-O84 Delivery	0.884	0.116
M25.5 Pain in joint	0.883	0.117
N17-N19 Renal failure	0.883	0.117
M79.6 Pain in limb	0.882	0.118
G57 Mononeuropathies of lower limb	0.881	0.119
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.876	0.124
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.875	0.125
Y83.1 Surgical operation with implant of artificial internal device	0.874	0.126
M10 Gout	0.874	0.126
S40-S49 Injuries to the shoulder and upper arm	0.869	0.131
N89.8 Other specified noninflammatory disorders of vagina	0.868	0.132
D75 Other diseases of blood and blood-forming organs	0.867	0.133
M25.7 Osteophyte	0.866	0.134
M80-M85 Disorders of bone density and structure	0.862	0.138
S50-S59 Injuries to the elbow and forearm	0.862	0.138
M79.8 Other specified soft tissue disorders	0.861	0.139
S80-S89 Injuries to the knee and lower leg	0.860	0.140
N81 Female genital prolapse	0.857	0.143
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.857	0.143
Q61 Cystic kidney disease	0.856	0.144
M31 Other necrotising vasculopathies	0.853	0.147
D60-D64 Aplastic and other anaemias	0.852	0.148
M25.8 Other specified joint disorders	0.850	0.150
Chapter I Certain infectious and parasitic diseases	0.850	0.150
H65 Nonsuppurative otitis media	0.843	0.157
M35 Other systemic involvement of connective tissue	0.840	0.160
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.839	0.161
M72 Fibroblastic disorders	0.838	0.162
N40 Hyperplasia of prostate	0.838	0.162
O72.1 Other immediate postpartum haemorrhage	0.837	0.163
G59 Mononeuropathy in diseases classified elsewhere	0.836	0.164
Chapter II Neoplasms	0.835	0.165
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.829	0.171
S90-S99 Injuries to the ankle and foot	0.829	0.171
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.828	0.172
O20 Haemorrhage in early pregnancy	0.828	0.172
M21 Other acquired deformities of limbs	0.826	0.174
M06.0 Seronegative rheumatoid arthritis	0.825	0.175
I24 Other acute ischaemic heart diseases	0.825	0.175
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.822	0.178
G55.2 Nerve root and plexus compressions in spondylosis	0.818	0.182
I25 Chronic ischaemic heart disease	0.817	0.183
I20 Angina pectoris	0.817	0.183
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.814	0.186
G57.6 Lesion of plantar nerve	0.813	0.187
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.812	0.188
N81.1 Cystocele	0.811	0.189
M20 Acquired deformities of fingers and toes	0.810	0.190
S61 Open wound of wrist and hand	0.809	0.191
M10.9 Gout, unspecified	0.808	0.192
S62 Fracture at wrist and hand level	0.805	0.195
N18 Chronic renal failure	0.804	0.196
G50 Disorders of trigeminal nerve	0.803	0.197
N86 Erosion and ectropion of cervix uteri	0.802	0.198
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.802	0.198
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.801	0.199
A30-A49 Other bacterial diseases	0.800	0.200
H66 Suppurative and unspecified otitis media	0.800	0.200
M05 Seropositive rheumatoid arthritis	0.799	0.201
M22 Disorders of patella	0.797	0.203
I25.1 Atherosclerotic heart disease	0.797	0.203
H61 Other disorders of external ear	0.795	0.205
S66 Injury of muscle and tendon at wrist and hand level	0.791	0.209
M79.62 Pain in limb (Upper arm)	0.791	0.209
M79.7 Fibromyalgia	0.790	0.210
G30-G32 Other degenerative diseases of the nervous system	0.790	0.210
M25.55 Pain in joint (Pelvic region and thigh)	0.788	0.212
I24.8 Other forms of acute ischaemic heart disease	0.788	0.212
O94-O99 Other obstetric conditions, not elsewhere classified	0.787	0.213
M91-M94 Chondropathies	0.787	0.213
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216
M34 Systemic sclerosis	0.783	0.217
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.782	0.218
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.781	0.219
C79 Secondary malignant neoplasm of other sites	0.781	0.219
O64 Obstructed labour due to malposition and malpresentation of foetus	0.780	0.220
D75.1 Secondary polycythaemia	0.779	0.221
M79.1 Myalgia	0.778	0.222
Q61.3 Polycystic kidney, unspecified	0.777	0.223
O20.0 Threatened abortion	0.776	0.224
O80 Single spontaneous delivery	0.770	0.230
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.770	0.230
S00-S09 Injuries to the head	0.769	0.231
I60-I69 Cerebrovascular diseases	0.768	0.232
O72.0 Third-stage haemorrhage	0.768	0.232
S22 Fracture of rib(s), sternum and thoracic spine	0.768	0.232
M79.09 Rheumatism, unspecified (Site unspecified)	0.767	0.233
T66-T78 Other and unspecified effects of external causes	0.766	0.234
T84.3 Mechanical complication of other bone devices, implants and grafts	0.766	0.234
N87 Dysplasia of cervix uteri	0.765	0.234
T86 Failure and rejection of transplanted organs and tissues	0.765	0.235
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.764	0.236
I95-I99 Other and unspecified disorders of the circulatory system	0.764	0.236
G58 Other mononeuropathies	0.763	0.237
M35.3 Polymyalgia rheumatica	0.762	0.238
N42 Other disorders of prostate	0.759	0.241
N99-N99 Other disorders of the genitourinary system	0.758	0.241
D50-D53 Nutritional anaemias	0.757	0.243
W20-W49 Exposure to inanimate mechanical forces	0.755	0.244
Q61.2 Polycystic kidney, adult type	0.754	0.246
N41 Inflammatory diseases of prostate	0.752	0.248
S69 Other and unspecified injuries of wrist and hand	0.751	0.249
Chapter XXII Codes for special purposes	0.751	0.249
M25.0 Haemarthrosis	0.750	0.250
H71 Cholesteatoma of middle ear	0.749	0.251
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.748	0.252
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.748	0.252
G70-G73 Diseases of myoneural junction and muscle	0.745	0.255
M25.84 Other specified joint disorders (Hand)	0.745	0.255
M79.86 Other specified soft tissue disorders (Lower leg)	0.744	0.256
N84 Polyp of female genital tract	0.743	0.257
H90-H95 Other disorders of ear	0.743	0.257
M79.00 Rheumatism, unspecified (Multiple sites)	0.742	0.258
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.742	0.258
M10.99 Gout, unspecified (Site unspecified)	0.740	0.260
O66 Other obstructed labour	0.740	0.260
M80 Osteoporosis with pathological fracture	0.740	0.260
M31.6 Other giant cell arteritis	0.739	0.261
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.739	0.261
X50-X57 Overexertion, travel and privation	0.739	0.261
H61.2 Impacted cerumen	0.739	0.261
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.739	0.261
G59.0 Diabetic mononeuropathy	0.737	0.263
O24 Diabetes mellitus in pregnancy	0.735	0.265
D37-D48 Neoplasms of uncertain or unknown behaviour	0.733	0.267
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.732	0.268
D64 Other anaemias	0.731	0.269
M20.4 Other hammer toe(s) (acquired)	0.729	0.271
M65-M68 Disorders of synovium and tendon	0.729	0.271
T90 Sequelae of injuries of head	0.729	0.271
H65.3 Chronic mucoid otitis media	0.728	0.272
D75.9 Disease of blood and blood-forming organs, unspecified	0.728	0.272
G90-G99 Other disorders of the nervous system	0.727	0.272
M84 Disorders of continuity of bone	0.727	0.273
X40-X49 Accidental poisoning by and exposure to noxious substances	0.726	0.274
N17 Acute renal failure	0.726	0.274
O82 Single delivery by Caesarean section	0.724	0.276
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.723	0.277
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.722	0.278
M25.57 Pain in joint (Ankle and foot)	0.721	0.278
S50 Superficial injury of forearm	0.720	0.279
M25.4 Effusion of joint	0.720	0.280
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.720	0.280
T88 Other complications of surgical and medical care, not elsewhere classified	0.719	0.281
O75 Other complications of labour and delivery, not elsewhere classified	0.718	0.282
Q80-Q89 Other congenital malformations	0.718	0.282
A41 Other septicaemia	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
M25.51 Pain in joint (Shoulder region)	0.717	0.283
M25.77 Osteophyte (Ankle and foot)	0.716	0.284
T85 Complications of other internal prosthetic devices, implants and grafts	0.716	0.284
I20.0 Unstable angina	0.716	0.284
M76 Enthesopathies of lower limb, excluding foot	0.715	0.285
M73 Soft tissue disorders in diseases classified elsewhere	0.715	0.285
M71 Other bursopathies	0.715	0.285
M79.60 Pain in limb (Multiple sites)	0.715	0.285
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.714	0.285
M33 Dermatopolymyositis	0.714	0.285
M32 Systemic lupus erythematosus	0.714	0.285
M30 Polyarteritis nodosa and related conditions	0.714	0.285
T91 Sequelae of injuries of neck and trunk	0.714	0.286
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.714	0.286
G55.3 Nerve root and plexus compressions in other dorsopathies	0.714	0.286
Q20-Q28 Congenital malformations of the circulatory system	0.714	0.286
M11 Other crystal arthropathies	0.714	0.286
X60-X84 Intentional self-harm	0.714	0.286
D63 Anaemia in chronic diseases classified elsewhere	0.713	0.287
O61 Failed induction of labour	0.712	0.288
T87 Complications peculiar to reattachment and amputation	0.712	0.288
T80 Complications following infusion, transfusion and therapeutic injection	0.712	0.288
T79-T79 Certain early complications of trauma	0.712	0.288
S64 Injury of nerves at wrist and hand level	0.711	0.289
D70 Agranulocytosis	0.709	0.291
M25.76 Osteophyte (Lower leg)	0.709	0.291
M79.83 Other specified soft tissue disorders (Forearm)	0.708	0.291
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.708	0.292
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.708	0.292
O85-O92 Complications predominantly related to the puerperium	0.708	0.292
V80-V89 Other land transport accidents	0.707	0.293
M79.9 Soft tissue disorder, unspecified	0.707	0.293
M79.5 Residual foreign body in soft tissue	0.707	0.293
M79.4 Hypertrophy of (infrapatellar) fat pad	0.707	0.293
M79.3 Panniculitis, unspecified	0.707	0.293
M79.2 Neuralgia and neuritis, unspecified	0.707	0.293
M79.63 Pain in limb (Forearm)	0.707	0.293
B15-B19 Viral hepatitis	0.706	0.293
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.706	0.294
G00-G09 Inflammatory diseases of the central nervous system	0.706	0.294
S60 Superficial injury of wrist and hand	0.706	0.294
I20.1 Angina pectoris with documented spasm	0.704	0.296
Y40 Systemic antibiotics	0.703	0.296
S89 Other and unspecified injuries of lower leg	0.703	0.297
A49 Bacterial infection of unspecified site	0.702	0.298
G51 Facial nerve disorders	0.702	0.298
H60 Otitis externa	0.701	0.299
M25.9 Joint disorder, unspecified	0.701	0.299
M25.6 Stiffness of joint, not elsewhere classified	0.701	0.299
M25.3 Other instability of joint	0.701	0.299
M25.2 Flail joint	0.701	0.299
M25.1 Fistula of joint	0.701	0.299
C51-C58 Malignant neoplasms of female genital organs	0.701	0.299
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.700	0.300
Y10-Y34 Event of undetermined intent	0.700	0.300
Y00-Y09 Assault	0.700	0.300
X85-X99 Assault	0.700	0.300
X58-X59 Accidental exposure to other and unspecified factors	0.700	0.300
X30-X39 Exposure to forces of nature	0.700	0.300
X20-X29 Contact with venomous animals and plants	0.700	0.300
X10-X19 Contact with heat and hot substances	0.700	0.300
X00-X09 Exposure to smoke, fire and flames	0.700	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300
W75-W84 Other accidental threats to breathing	0.700	0.300
W65-W74 Accidental drowning and submersion	0.700	0.300
W50-W64 Exposure to animate mechanical forces	0.700	0.300
V98-V99 Other and unspecified transport accidents	0.700	0.300
V95-V97 Air and space transport accidents	0.700	0.300
V90-V94 Water transport accidents	0.700	0.300
V70-V79 Bus occupant injured in transport accident	0.700	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300
V40-V49 Car occupant injured in transport accident	0.700	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300
V20-V29 Motorcycle rider injured in transport accident	0.700	0.300
V01-V09 Pedestrian injured in transport accident	0.700	0.300
N98 Complications associated with artificial fertilisation	0.700	0.300
N91 Absent, scanty and rare menstruation	0.700	0.300
N82 Fistulae involving female genital tract	0.700	0.300
N96 Habitual aborter	0.700	0.300
T93 Sequelae of injuries of lower limb	0.700	0.300
H72 Perforation of tympanic membrane	0.700	0.300
T92 Sequelae of injuries of upper limb	0.699	0.301
G54 Nerve root and plexus disorders	0.698	0.301
G53 Cranial nerve disorders in diseases classified elsewhere	0.698	0.301
G52 Disorders of other cranial nerves	0.698	0.301
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.698	0.302
M40-M43 Deforming dorsopathies	0.697	0.303
H80-H83 Diseases of inner ear	0.695	0.305
H65.9 Nonsuppurative otitis media, unspecified	0.694	0.306
S82 Fracture of lower leg, including ankle	0.693	0.307
Q00-Q07 Congenital malformations of the nervous system	0.693	0.307
M14 Arthropathies in other diseases classified elsewhere	0.693	0.307
M12 Other specific arthropathies	0.693	0.307
M09 Juvenile arthritis in diseases classified elsewhere	0.693	0.307
M08 Juvenile arthritis	0.693	0.307
Q50-Q56 Congenital malformations of genital organs	0.692	0.308
M24 Other specific joint derangements	0.692	0.308
D75.2 Essential thrombocytosis	0.692	0.308
S51 Open wound of forearm	0.691	0.309
D55-D59 Haemolytic anaemias	0.689	0.311
N81.8 Other female genital prolapse	0.689	0.311
N81.2 Incomplete uterovaginal prolapse	0.689	0.311
S65 Injury of blood vessels at wrist and hand level	0.688	0.312
N00-N08 Glomerular diseases	0.687	0.313
S46 Injury of muscle and tendon at shoulder and upper arm level	0.687	0.313
S67 Crushing injury of wrist and hand	0.687	0.313
S80 Superficial injury of lower leg	0.687	0.313
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.687	0.313
M07 Psoriatic and enteropathic arthropathies	0.686	0.314
D00-D09 In situ neoplasms	0.686	0.314
N43 Hydrocele and spermatocele	0.686	0.314
M06.9 Rheumatoid arthritis, unspecified	0.685	0.315
M79.67 Pain in limb (Ankle and foot)	0.684	0.316
M77 Other enthesopathies	0.682	0.318
S20 Superficial injury of thorax	0.682	0.318
G20-G26 Extrapyramidal and movement disorders	0.682	0.318
N45 Orchitis and epididymitis	0.681	0.319
N87.9 Dysplasia of cervix uteri, unspecified	0.681	0.319
O72.2 Delayed and secondary postpartum haemorrhage	0.680	0.320
C79.9 Secondary malignant neoplasm, unspecified site	0.680	0.320
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.680	0.320
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.680	0.320
Q38-Q45 Other congenital malformations of the digestive system	0.680	0.320
Q35-Q37 Cleft lip and cleft palate	0.680	0.320
Q30-Q34 Congenital malformations of the respiratory system	0.680	0.320
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.680	0.320
G50.0 Trigeminal neuralgia	0.680	0.320
M25.53 Pain in joint (Forearm)	0.680	0.320
S68 Traumatic amputation of wrist and hand	0.679	0.321
M05.9 Seropositive rheumatoid arthritis, unspecified	0.679	0.321
M86-M90 Other osteopathies	0.678	0.322
D75.8 Other specified diseases of blood and blood-forming organs	0.677	0.323
N10-N16 Renal tubulo-interstitial diseases	0.677	0.323
I05-I09 Chronic rheumatic heart diseases	0.677	0.323
G55.0 Nerve root and plexus compressions in neoplastic disease	0.676	0.324
M75.8 Other shoulder lesions	0.675	0.325
M75.9 Shoulder lesion, unspecified	0.675	0.325
M75.2 Bicipital tendinitis	0.675	0.325
M25.75 Osteophyte (Pelvic region and thigh)	0.674	0.326
N18.4 Chronic kidney disease, stage 4	0.674	0.326
Y60-Y69 Misadventures to patients during surgical and medical care	0.672	0.328
O80.0 Spontaneous vertex delivery	0.672	0.328
D80-D89 Certain disorders involving the immune mechanism	0.672	0.328
M25.59 Pain in joint (Site unspecified)	0.671	0.328
G62 Other polyneuropathies	0.671	0.329
O74 Complications of anaesthesia during labour and delivery	0.670	0.330
O71 Other obstetric trauma	0.670	0.330
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.670	0.330
O65 Obstructed labour due to maternal pelvic abnormality	0.670	0.330
O60 Preterm delivery	0.670	0.330
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.669	0.330
Chapter VII Diseases of the eye and adnexa	0.669	0.331
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.669	0.331
H74 Other disorders of middle ear and mastoid	0.669	0.331
H70 Mastoiditis and related conditions	0.669	0.331
H69 Other disorders of Eustachian tube	0.669	0.331
H68 Eustachian salpingitis and obstruction	0.669	0.331
H67 Otitis media in diseases classified elsewhere	0.669	0.331
S29 Other and unspecified injuries of thorax	0.669	0.331
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.668	0.332
V10-V19 Pedal cyclist injured in transport accident	0.668	0.332
I60 Subarachnoid haemorrhage	0.667	0.333
M70 Soft tissue disorders related to use, overuse and pressure	0.666	0.333
N83.0 Follicular cyst of ovary	0.666	0.334
T84.1 Mechanical complication of internal fixation device of bones of limb	0.664	0.335
N18.3 Chronic kidney disease, stage 3	0.664	0.336
S61.1 Open wound of finger(s) with damage to nail	0.663	0.336
S49 Other and unspecified injuries of shoulder and upper arm	0.663	0.337
D61 Other aplastic anaemias	0.663	0.337
Y83.2 Surgical operation with anastomosis, bypass or graft	0.663	0.337
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.662	0.338
N95.9 Menopausal and perimenopausal disorder, unspecified	0.661	0.339
N95.3 States associated with artificial menopause	0.661	0.339
S43.1 Dislocation of acromioclavicular joint	0.661	0.339
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.661	0.339
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.660	0.339
S61.0 Open wound of finger(s) without damage to nail	0.659	0.341
W00-W19 Falls	0.658	0.342
M20.0 Deformity of finger(s)	0.657	0.343
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.657	0.343
M75.5 Bursitis of shoulder	0.656	0.343
H66.3 Other chronic suppurative otitis media	0.656	0.344
M20.3 Other deformity of hallux (acquired)	0.656	0.344
N81.6 Rectocele	0.656	0.344
I00-I02 Acute rheumatic fever	0.655	0.344
M96.0 Pseudarthrosis after fusion or arthrodesis	0.655	0.345
M15-M19 Arthrosis	0.654	0.346
N18.9 Chronic renal failure, unspecified	0.654	0.346
N51 Disorders of male genital organs in diseases classified elsewhere	0.653	0.347
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.653	0.347
N46 Male infertility	0.653	0.347
N44 Torsion of testis	0.653	0.347
M21.2 Flexion deformity	0.653	0.347
N89.9 Noninflammatory disorder of vagina, unspecified	0.653	0.347
N89.7 Haematocolpos	0.653	0.347
N89.6 Tight hymenal ring	0.653	0.347
N89.4 Leukoplakia of vagina	0.653	0.347
N89.3 Dysplasia of vagina, unspecified	0.653	0.347
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.653	0.347
N89.1 Moderate vaginal dysplasia	0.653	0.347
N89.0 Mild vaginal dysplasia	0.653	0.347
B99-B99 Other infectious diseases	0.652	0.348
S32 Fracture of lumbar spine and pelvis	0.652	0.348
Q61.0 Congenital single renal cyst	0.651	0.349
M79.64 Pain in limb (Hand)	0.651	0.349
C77.3 Axillary and upper limb lymph nodes	0.650	0.350
M79.79 Fibromyalgia (Site unspecified)	0.650	0.350
M25.54 Pain in joint (Hand)	0.649	0.350
S27 Injury of other and unspecified intrathoracic organs	0.649	0.351
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.649	0.351
D74 Methaemoglobinaemia	0.649	0.351
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.649	0.351
D71 Functional disorders of polymorphonuclear neutrophils	0.649	0.351
H66.9 Otitis media, unspecified	0.648	0.351
S61.7 Multiple open wounds of wrist and hand	0.648	0.352
N95.1 Menopausal and female climacteric states	0.647	0.353
N50 Other disorders of male genital organs	0.646	0.354
D64.9 Anaemia, unspecified	0.644	0.356
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.644	0.356
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.644	0.356
O72.3 Postpartum coagulation defects	0.644	0.356
I95 Hypotension	0.644	0.356
T98 Sequelae of other and unspecified effects of external causes	0.643	0.357
T95 Sequelae of burns, corrosions and frostbite	0.643	0.357
T94 Sequelae of injuries involving multiple and unspecified body regions	0.643	0.357
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.643	0.357
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.643	0.357
T15-T19 Effects of foreign body entering through natural orifice	0.643	0.357
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.642	0.358
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.642	0.358
T82.4 Mechanical complication of vascular dialysis catheter	0.642	0.358
T82.3 Mechanical complication of other vascular grafts	0.642	0.358
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.642	0.358
T82.1 Mechanical complication of cardiac electronic device	0.642	0.358
T82.0 Mechanical complication of heart valve prosthesis	0.642	0.358
Q64 Other congenital malformations of urinary system	0.641	0.359
Q63 Other congenital malformations of kidney	0.641	0.359
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.641	0.359
Q60 Renal agenesis and other reduction defects of kidney	0.641	0.359
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.641	0.359
O73 Retained placenta and membranes, without haemorrhage	0.641	0.359
M25.87 Other specified joint disorders (Ankle and foot)	0.641	0.359
Y95 Nosocomial condition	0.641	0.359
T51 Toxic effect of alcohol	0.640	0.360
I20.9 Angina pectoris, unspecified	0.640	0.360
G57.8 Other mononeuropathies of lower limb	0.640	0.360
I23 Certain current complications following acute myocardial infarction	0.640	0.360
O29 Complications of anaesthesia during pregnancy	0.639	0.361
O28 Abnormal findings on antenatal screening of mother	0.639	0.361
O23 Infections of genito-urinary tract in pregnancy	0.639	0.361
O22 Venous complications in pregnancy	0.639	0.361
O21 Excessive vomiting in pregnancy	0.639	0.361
O25 Malnutrition in pregnancy	0.639	0.361
M06.8 Other specified rheumatoid arthritis	0.639	0.361
M06.4 Inflammatory polyarthropathy	0.639	0.361
M06.3 Rheumatoid nodule	0.639	0.361
M06.2 Rheumatoid bursitis	0.639	0.361
M06.1 Adult-onset Still's disease	0.639	0.361
S22.3 Fracture of rib	0.639	0.361
Chapter X Diseases of the respiratory system	0.638	0.362
G30 Alzheimer's disease	0.637	0.363
C79.2 Secondary malignant neoplasm of skin	0.637	0.363
M79.08 Rheumatism, unspecified (Other)	0.636	0.363
M79.07 Rheumatism, unspecified (Ankle and foot)	0.636	0.363
M79.06 Rheumatism, unspecified (Lower leg)	0.636	0.363
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.636	0.363
M79.04 Rheumatism, unspecified (Hand)	0.636	0.363
M79.03 Rheumatism, unspecified (Forearm)	0.636	0.363
M79.02 Rheumatism, unspecified (Upper arm)	0.636	0.363
M79.01 Rheumatism, unspecified (Shoulder region)	0.636	0.363
M31.3 Wegener's granulomatosis	0.636	0.364
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.636	0.364
S26 Injury of heart	0.636	0.364
S25 Injury of blood vessels of thorax	0.636	0.364
S24 Injury of nerves and spinal cord at thorax level	0.636	0.364
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.636	0.364
S21 Open wound of thorax	0.636	0.364
M45-M49 Spondylopathies	0.636	0.364
Y83.4 Other reconstructive surgery	0.636	0.364
N97 Female infertility	0.636	0.364
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.636	0.364
H62 Disorders of external ear in diseases classified elsewhere	0.635	0.365
S22.0 Fracture of thoracic vertebra	0.635	0.365
N70-N77 Inflammatory diseases of female pelvic organs	0.635	0.365
O62 Abnormalities of forces of labour	0.634	0.365
N81.9 Female genital prolapse, unspecified	0.634	0.366
O84 Multiple delivery	0.634	0.366
O83 Other assisted single delivery	0.634	0.366
O81 Single delivery by forceps and vacuum extractor	0.634	0.366
C50-C50 Malignant neoplasm of breast	0.634	0.366
M22.4 Chondromalacia patellae	0.634	0.366
S62.3 Fracture of other metacarpal bone	0.634	0.366
G40-G47 Episodic and paroxysmal disorders	0.634	0.366
M25.58 Pain in joint (Other)	0.633	0.367
M25.52 Pain in joint (Upper arm)	0.633	0.367
M80.9 Unspecified osteoporosis with pathological fracture	0.633	0.367

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations