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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74339132
log Bayes Factor = 14.7722
Chromosome 2   position 54,585,354  (GRCh37) Explore rs74339132 on Ensembl!
Variant rs74339132 is part of Cluster X0204

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
S00-S09 Injuries to the head
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
S60-S69 Injuries to the wrist and hand
0.988 0.012 0.000
M06 Other rheumatoid arthritis
0.988 0.012 0.000
I20 Angina pectoris
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.985 0.015 0.000
S01 Open wound of head
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.980 0.020 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.977 0.023 0.000
I21 Acute myocardial infarction
0.973 0.027 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.971 0.029 0.000
S61 Open wound of wrist and hand
0.964 0.036 0.000
I21.9 Acute myocardial infarction, unspecified
0.962 0.038 0.000
G40 Epilepsy
0.950 0.050 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.949 0.051 0.000
S01.1 Open wound of eyelid and periocular area
0.944 0.056 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.942 0.058 0.000
G40.9 Epilepsy, unspecified
0.939 0.061 0.000
I20.8 Other forms of angina pectoris
0.935 0.065 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.928 0.072 0.000
S61.1 Open wound of finger(s) with damage to nail
0.927 0.073 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
I20.9 Angina pectoris, unspecified
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.920 0.080 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.916 0.084 0.000
I25.1 Atherosclerotic heart disease
0.912 0.088 0.000
Chapter II Neoplasms
0.903 0.097 0.000
M65-M68 Disorders of synovium and tendon
0.903 0.097 0.000
C15-C26 Malignant neoplasms of digestive organs
0.897 0.103 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.897 0.103 0.000
G81 Hemiplegia
0.883 0.117 0.000
M79.6 Pain in limb
0.878 0.122 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.877 0.123 0.000
S09 Other and unspecified injuries of head
0.874 0.126 0.000
S80-S89 Injuries to the knee and lower leg
0.867 0.133 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.865 0.135 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.864 0.136 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.862 0.138 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.855 0.145 0.000
M20-M25 Other joint disorders
0.852 0.148 0.000
W20-W49 Exposure to inanimate mechanical forces
0.852 0.148 0.000
S02 Fracture of skull and facial bones
0.845 0.155 0.000
T66-T78 Other and unspecified effects of external causes
0.844 0.156 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.844 0.156 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.842 0.158 0.000
G81.9 Hemiplegia, unspecified
0.840 0.160 0.000
Chapter V Mental and behavioural disorders
0.840 0.160 0.000
C20 Malignant neoplasm of rectum
0.837 0.163 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.836 0.164 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.834 0.166 0.000
S61.0 Open wound of finger(s) without damage to nail
0.834 0.166 0.000
M65 Synovitis and tenosynovitis
0.832 0.168 0.000
Y44 Agents primarily affecting blood constituents
0.827 0.173 0.000
T79-T79 Certain early complications of trauma
0.827 0.173 0.000
M80-M85 Disorders of bone density and structure
0.825 0.174 0.000
M06.0 Seronegative rheumatoid arthritis
0.825 0.175 0.000
S01.0 Open wound of scalp
0.823 0.177 0.000
G20-G26 Extrapyramidal and movement disorders
0.822 0.178 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.821 0.179 0.000
S68 Traumatic amputation of wrist and hand
0.820 0.180 0.000
X60-X84 Intentional self-harm
0.819 0.181 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.819 0.181 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.818 0.182 0.000
Chapter VIII Diseases of the ear and mastoid process
0.817 0.183 0.000
S64 Injury of nerves at wrist and hand level
0.816 0.184 0.000
Chapter VII Diseases of the eye and adnexa
0.815 0.185 0.000
M05 Seropositive rheumatoid arthritis
0.814 0.186 0.000
Q60-Q64 Congenital malformations of the urinary system
0.813 0.187 0.000
M07 Psoriatic and enteropathic arthropathies
0.810 0.190 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.809 0.191 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.807 0.193 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.805 0.195 0.000
S01.8 Open wound of other parts of head
0.804 0.196 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.804 0.196 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.803 0.197 0.000
M79.8 Other specified soft tissue disorders
0.798 0.202 0.000
T17 Foreign body in respiratory tract
0.793 0.207 0.000
W00-W19 Falls
0.791 0.209 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.790 0.210 0.000
S09.9 Unspecified injury of head
0.787 0.213 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.785 0.215 0.000
S01.4 Open wound of cheek and temporomandibular area
0.785 0.215 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.785 0.215 0.000
M79.66 Pain in limb (Lower leg)
0.784 0.216 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
S67 Crushing injury of wrist and hand
0.775 0.225 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.775 0.225 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.773 0.227 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.773 0.227 0.000
M79.2 Neuralgia and neuritis, unspecified
0.772 0.228 0.000
Z50 Care involving use of rehabilitation procedures
0.771 0.229 0.000
Chapter XXI Factors influencing health status and contact with health services
0.771 0.229 0.000
Chapter I Certain infectious and parasitic diseases
0.771 0.229 0.000
S05 Injury of eye and orbit
0.769 0.231 0.000
Y43 Primarily systemic agents
0.769 0.231 0.000
S82 Fracture of lower leg, including ankle
0.769 0.231 0.000
S90-S99 Injuries to the ankle and foot
0.766 0.234 0.000
Z50.1 Other physical therapy
0.762 0.238 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.761 0.239 0.000
Y44.2 Anticoagulants
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
I25.3 Aneurysm of heart
0.759 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
S62 Fracture at wrist and hand level
0.757 0.243 0.000
C51-C58 Malignant neoplasms of female genital organs
0.757 0.243 0.000
S61.8 Open wound of other parts of wrist and hand
0.755 0.245 0.000
S01.5 Open wound of lip and oral cavity
0.755 0.245 0.000
M79.69 Pain in limb (Site unspecified)
0.752 0.248 0.000
I20.1 Angina pectoris with documented spasm
0.752 0.248 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
M13 Other arthritis
0.751 0.249 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.750 0.250 0.000
M15-M19 Arthrosis
0.750 0.250 0.000
C18 Malignant neoplasm of colon
0.747 0.253 0.000
W25 Contact with sharp glass
0.746 0.254 0.000
C21 Malignant neoplasm of anus and anal canal
0.745 0.255 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.745 0.255 0.000
S06 Intracranial injury
0.745 0.255 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.744 0.256 0.000
G82 Paraplegia and tetraplegia
0.743 0.257 0.000
X20-X29 Contact with venomous animals and plants
0.743 0.257 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.741 0.259 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.740 0.260 0.000
Chapter XI Diseases of the digestive system
0.739 0.261 0.000
I22 Subsequent myocardial infarction
0.739 0.261 0.000
T40.2 Other opioids
0.738 0.262 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.738 0.262 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.737 0.263 0.000
Chapter X Diseases of the respiratory system
0.736 0.264 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.735 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.733 0.267 0.000
T78 Adverse effects, not elsewhere classified
0.732 0.268 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.732 0.268 0.000
M50-M54 Other dorsopathies
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.731 0.269 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.731 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.730 0.270 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.730 0.270 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.729 0.270 0.000
J00-J06 Acute upper respiratory infections
0.729 0.271 0.000
T90 Sequelae of injuries of head
0.728 0.272 0.000
G80 Infantile cerebral palsy
0.724 0.276 0.000
C25 Malignant neoplasm of pancreas
0.724 0.276 0.000
G41 Status epilepticus
0.723 0.277 0.000
Y95 Nosocomial condition
0.722 0.278 0.000
T17.2 Foreign body in pharynx
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.721 0.279 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.721 0.279 0.000
M35 Other systemic involvement of connective tissue
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M79.7 Fibromyalgia
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
T98 Sequelae of other and unspecified effects of external causes
0.716 0.284 0.000
M84 Disorders of continuity of bone
0.716 0.284 0.000
D00-D09 In situ neoplasms
0.716 0.284 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
G44 Other headache syndromes
0.715 0.285 0.000
G45.3 Amaurosis fugax
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.285 0.000
S07 Crushing injury of head
0.714 0.285 0.000
S04 Injury of cranial nerves
0.714 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.285 0.000
M23 Internal derangement of knee
0.715 0.285 0.000
T40.4 Other synthetic narcotics
0.713 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.713 0.287 0.000
M12 Other specific arthropathies
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.713 0.287 0.000
I20.0 Unstable angina
0.713 0.287 0.000
S00 Superficial injury of head
0.711 0.289 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
S65 Injury of blood vessels at wrist and hand level
0.709 0.291 0.000
M06.8 Other specified rheumatoid arthritis
0.708 0.292 0.000
M06.4 Inflammatory polyarthropathy
0.708 0.292 0.000
M06.3 Rheumatoid nodule
0.708 0.292 0.000
M06.2 Rheumatoid bursitis
0.708 0.292 0.000
M06.1 Adult-onset Still's disease
0.708 0.292 0.000
H60-H62 Diseases of external ear
0.708 0.292 0.000
M86-M90 Other osteopathies
0.707 0.293 0.000
M17 Gonarthrosis [arthrosis of knee]
0.706 0.294 0.000
I00-I02 Acute rheumatic fever
0.706 0.294 0.000
S01.9 Open wound of head, part unspecified
0.704 0.295 0.000
S01.7 Multiple open wounds of head
0.704 0.296 0.000
M79.1 Myalgia
0.704 0.296 0.000
H65-H75 Diseases of middle ear and mastoid
0.704 0.296 0.000
S20-S29 Injuries to the thorax
0.703 0.297 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.703 0.297 0.000
M45-M49 Spondylopathies
0.703 0.297 0.000
M22 Disorders of patella
0.703 0.297 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.702 0.298 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.702 0.298 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.702 0.298 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.702 0.298 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.701 0.299 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.701 0.299 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.701 0.299 0.000
G45.0 Vertebro-basilar artery syndrome
0.701 0.299 0.000
M79.64 Pain in limb (Hand)
0.700 0.300 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.699 0.301 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.699 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.697 0.303 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.696 0.304 0.000
I60-I69 Cerebrovascular diseases
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.695 0.304 0.000
G70-G73 Diseases of myoneural junction and muscle
0.694 0.306 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.694 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.306 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.694 0.306 0.000
W44 Foreign body entering into or through eye or natural orifice
0.692 0.308 0.000
Q61 Cystic kidney disease
0.692 0.308 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.691 0.309 0.000
S61.7 Multiple open wounds of wrist and hand
0.690 0.310 0.000
T92 Sequelae of injuries of upper limb
0.690 0.310 0.000
Q80-Q89 Other congenital malformations
0.689 0.311 0.000
F30-F39 Mood [affective] disorders
0.688 0.312 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.688 0.312 0.000
S01.2 Open wound of nose
0.687 0.313 0.000
Z51 Other medical care
0.687 0.313 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.686 0.314 0.000
S50-S59 Injuries to the elbow and forearm
0.686 0.314 0.000
M21 Other acquired deformities of limbs
0.686 0.314 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.685 0.315 0.000
S81 Open wound of lower leg
0.685 0.315 0.000
S02.3 Fracture of orbital floor
0.683 0.317 0.000
J06.9 Acute upper respiratory infection, unspecified
0.681 0.319 0.000
G40.8 Other epilepsy
0.681 0.319 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.681 0.319 0.000
G40.5 Special epileptic syndromes
0.681 0.319 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.681 0.319 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.681 0.319 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.681 0.319 0.000
S69 Other and unspecified injuries of wrist and hand
0.681 0.319 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.681 0.319 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.681 0.319 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.681 0.319 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.681 0.319 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.681 0.319 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.681 0.319 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
T36 Poisoning by systemic antibiotics
0.681 0.319 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.681 0.319 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.680 0.320 0.000
Z50.8 Care involving use of rehabilitation procedures
0.680 0.320 0.000
M07.3 Other psoriatic arthropathies
0.678 0.321 0.000
M11 Other crystal arthropathies
0.678 0.321 0.000
G47 Sleep disorders
0.677 0.323 0.000
S82.8 Fractures of other parts of lower leg
0.676 0.324 0.000
Q43 Other congenital malformations of intestine
0.675 0.325 0.000
M34 Systemic sclerosis
0.675 0.325 0.000
M17.0 Primary gonarthrosis, bilateral
0.675 0.325 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.673 0.327 0.000
S02.4 Fracture of malar and maxillary bones
0.673 0.327 0.000
T91 Sequelae of injuries of neck and trunk
0.673 0.327 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.672 0.328 0.000
W25.9 Unspecified place
0.671 0.329 0.000
M23.3 Other meniscus derangements
0.670 0.330 0.000
Y40 Systemic antibiotics
0.670 0.330 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.668 0.332 0.000
M79.63 Pain in limb (Forearm)
0.667 0.333 0.000
G25 Other extrapyramidal and movement disorders
0.667 0.333 0.000
K01 Embedded and impacted teeth
0.665 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.665 0.335 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.335 0.000
Q35-Q37 Cleft lip and cleft palate
0.665 0.335 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.665 0.335 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.665 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.336 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.663 0.337 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.663 0.337 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.663 0.337 0.000
Y43.1 Antineoplastic antimetabolites
0.662 0.338 0.000
G83 Other paralytic syndromes
0.661 0.338 0.000
F99-F99 Unspecified mental disorder
0.661 0.339 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.660 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
Y48 Anaesthetics and therapeutic gases
0.660 0.340 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.660 0.340 0.000
M79.62 Pain in limb (Upper arm)
0.659 0.341 0.000
Z51.0 Radiotherapy session
0.657 0.343 0.000
M79.9 Soft tissue disorder, unspecified
0.657 0.343 0.000
M79.5 Residual foreign body in soft tissue
0.657 0.343 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.657 0.343 0.000
M79.3 Panniculitis, unspecified
0.657 0.343 0.000
S70-S79 Injuries to the hip and thigh
0.657 0.343 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.655 0.344 0.000
G24 Dystonia
0.655 0.345 0.000
S02.2 Fracture of nasal bones
0.655 0.345 0.000
S01.3 Open wound of ear
0.655 0.345 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.654 0.346 0.000
C56 Malignant neoplasm of ovary
0.654 0.346 0.000
F60-F69 Disorders of adult personality and behaviour
0.653 0.347 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.650 0.350 0.000
H30-H36 Disorders of choroid and retina
0.650 0.350 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.649 0.351 0.000
M67 Other disorders of synovium and tendon
0.649 0.351 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.649 0.351 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.649 0.351 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.647 0.352 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.647 0.352 0.000
M17.1 Other primary gonarthrosis
0.647 0.353 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.647 0.353 0.000
M66 Spontaneous rupture of synovium and tendon
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.645 0.355 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.644 0.355 0.000
M71 Other bursopathies
0.644 0.356 0.000
M65.8 Other synovitis and tenosynovitis
0.644 0.356 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.643 0.356 0.000
C17 Malignant neoplasm of small intestine
0.643 0.356 0.000
C23 Malignant neoplasm of gallbladder
0.643 0.356 0.000
S60 Superficial injury of wrist and hand
0.643 0.357 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.642 0.358 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.640 0.360 0.000
K08 Other disorders of teeth and supporting structures
0.640 0.360 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.640 0.360 0.000
Q50-Q56 Congenital malformations of genital organs
0.640 0.360 0.000
K11 Diseases of salivary glands
0.640 0.360 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.639 0.361 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.639 0.361 0.000
G11 Hereditary ataxia
0.639 0.361 0.000
F31 Bipolar affective disorder
0.638 0.362 0.000
W06 Fall involving bed
0.638 0.362 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.638 0.362 0.000
K14 Diseases of tongue
0.638 0.362 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.637 0.363 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.637 0.363 0.000
S32 Fracture of lumbar spine and pelvis
0.637 0.363 0.000
M79.88 Other specified soft tissue disorders (Other)
0.636 0.364 0.000
H55-H59 Other disorders of eye and adnexa
0.635 0.365 0.000
F20 Schizophrenia
0.634 0.366 0.000
H65 Nonsuppurative otitis media
0.634 0.366 0.000
G81.1 Spastic hemiplegia
0.633 0.367 0.000
G81.0 Flaccid hemiplegia
0.633 0.367 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.632 0.368 0.000
M24 Other specific joint derangements
0.632 0.368 0.000
T20 Burn and corrosion of head and neck
0.631 0.369 0.000
I69 Sequelae of cerebrovascular disease
0.630 0.370 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.630 0.370 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.630 0.370 0.000
Z54 Convalescence
0.630 0.370 0.000
M79.68 Pain in limb (Other)
0.629 0.370 0.000
M79.61 Pain in limb (Shoulder region)
0.629 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.629 0.371 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.629 0.371 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.629 0.371 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.629 0.371 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.628 0.372 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.628 0.372 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.628 0.372 0.000
M13.0 Polyarthritis, unspecified
0.627 0.373 0.000
S09.8 Other specified injuries of head
0.627 0.373 0.000
S09.7 Multiple injuries of head
0.627 0.373 0.000
S09.2 Traumatic rupture of ear drum
0.627 0.373 0.000
S09.1 Injury of muscle and tendon of head
0.627 0.373 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.627 0.373 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.627 0.373 0.000
S12 Fracture of neck
0.626 0.373 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.626 0.373 0.000
S82.1 Fracture of upper end of tibia
0.626 0.374 0.000
T78.2 Anaphylactic shock, unspecified
0.626 0.374 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.625 0.375 0.000
D60-D64 Aplastic and other anaemias
0.625 0.375 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.624 0.376 0.000
C16 Malignant neoplasm of stomach
0.624 0.376 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.622 0.377 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.622 0.378 0.000
S88 Traumatic amputation of lower leg
0.622 0.378 0.000
S87 Crushing injury of lower leg
0.622 0.378 0.000
S86 Injury of muscle and tendon at lower leg level
0.622 0.378 0.000
S85 Injury of blood vessels at lower leg level
0.622 0.378 0.000
S84 Injury of nerves at lower leg level
0.622 0.378 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.622 0.378 0.000
T19 Foreign body in genito-urinary tract
0.620 0.380 0.000
T15 Foreign body on external eye
0.620 0.380 0.000
T16 Foreign body in ear
0.620 0.380 0.000
J00 Acute nasopharyngitis [common cold]
0.620 0.380 0.000
G43 Migraine
0.620 0.380 0.000
Z48 Other surgical follow-up care
0.619 0.381 0.000
W10 Fall on and from stairs and steps
0.619 0.381 0.000
T86 Failure and rejection of transplanted organs and tissues
0.618 0.382 0.000
S02.8 Fractures of other skull and facial bones
0.616 0.384 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.616 0.384 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.615 0.384 0.000
K01.1 Impacted teeth
0.615 0.385 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.614 0.386 0.000
G12 Spinal muscular atrophy and related syndromes
0.614 0.386 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.614 0.386 0.000
K05 Gingivitis and periodontal diseases
0.614 0.386 0.000
C18.0 Caecum
0.613 0.387 0.000
C09 Malignant neoplasm of tonsil
0.613 0.387 0.000
S62.5 Fracture of thumb
0.613 0.387 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.613 0.387 0.000
T40.8 Lysergide [LSD]
0.613 0.387 0.000
T40.7 Cannabis (derivatives)
0.613 0.387 0.000
T40.6 Other and unspecified narcotics
0.613 0.387 0.000
T40.5 Cocaine
0.613 0.387 0.000
T40.3 Methadone
0.613 0.387 0.000
T40.1 Heroin
0.613 0.387 0.000
T40.0 Opium
0.613 0.387 0.000
H61 Other disorders of external ear
0.612 0.388 0.000
M10 Gout
0.612 0.388 0.000
C15 Malignant neoplasm of oesophagus
0.612 0.388 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.611 0.389 0.000
M33 Dermatopolymyositis
0.611 0.389 0.000
M32 Systemic lupus erythematosus
0.611 0.389 0.000
M30 Polyarteritis nodosa and related conditions
0.611 0.389 0.000
M47 Spondylosis
0.611 0.389 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.611 0.389 0.000
W46 Contact with hypodermic needle
0.611 0.389 0.000
W45 Foreign body or object entering through skin
0.611 0.389 0.000
W43 Exposure to vibration
0.611 0.389 0.000
W42 Exposure to noise
0.611 0.389 0.000
W41 Exposure to high-pressure jet
0.611 0.389 0.000
W40 Explosion of other materials
0.611 0.389 0.000
W39 Discharge of firework
0.611 0.389 0.000
W38 Explosion and rupture of other specified pressurised devices
0.611 0.389 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.611 0.389 0.000
W36 Explosion and rupture of gas cylinder
0.611 0.389 0.000
W35 Explosion and rupture of boiler
0.611 0.389 0.000
W34 Discharge from other and unspecified firearms
0.611 0.389 0.000
W33 Rifle, shotgun and larger firearm discharge
0.611 0.389 0.000
W32 Handgun discharge
0.611 0.389 0.000
W31 Contact with other and unspecified machinery
0.611 0.389 0.000
W30 Contact with agricultural machinery
0.611 0.389 0.000
W28 Contact with powered lawn mower
0.611 0.389 0.000
W27 Contact with nonpowered hand tool
0.611 0.389 0.000
W26 Contact with knife, sword or dagger
0.611 0.389 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.611 0.389 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.611 0.389 0.000
W21 Striking against or struck by sports equipment
0.611 0.389 0.000
W20 Struck by thrown, projected or falling object
0.611 0.389 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.610 0.390 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.610 0.390 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.610 0.390 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.610 0.390 0.000
S64.4 Injury of digital nerve of other finger
0.608 0.392 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.608 0.392 0.000
X62.9 Unspecified place
0.608 0.392 0.000
H33 Retinal detachments and breaks
0.607 0.393 0.000
M35.3 Polymyalgia rheumatica
0.607 0.393 0.000
Z47 Other orthopaedic follow-up care
0.607 0.393 0.000
C21.0 Anus, unspecified
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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