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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76597414
log Bayes Factor = 16.1863
Chromosome 17   position 72,191,445  (GRCh37) Explore rs76597414 on Ensembl!
Variant rs76597414 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
I20 Angina pectoris
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.986 0.014 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.982 0.018 0.000
E10 Insulin-dependent diabetes mellitus
0.977 0.023 0.000
Chapter I Certain infectious and parasitic diseases
0.976 0.024 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
M70-M79 Other soft tissue disorders
0.972 0.028 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.971 0.029 0.000
I63 Cerebral infarction
0.969 0.031 0.000
S60-S69 Injuries to the wrist and hand
0.968 0.032 0.000
I25.2 Old myocardial infarction
0.963 0.037 0.000
E10.9 Without complications
0.963 0.037 0.000
I63.9 Cerebral infarction, unspecified
0.962 0.038 0.000
S00-S09 Injuries to the head
0.961 0.039 0.000
I95 Hypotension
0.959 0.041 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.954 0.046 0.000
I20.9 Angina pectoris, unspecified
0.950 0.050 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.950 0.050 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.948 0.052 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
Chapter II Neoplasms
0.942 0.058 0.000
I21 Acute myocardial infarction
0.934 0.066 0.000
Chapter X Diseases of the respiratory system
0.929 0.071 0.000
B95-B98 Bacterial, viral and other infectious agents
0.927 0.073 0.000
I24 Other acute ischaemic heart diseases
0.924 0.076 0.000
Y95 Nosocomial condition
0.923 0.077 0.000
I20.8 Other forms of angina pectoris
0.921 0.079 0.000
Y52 Agents primarily affecting the cardiovascular system
0.918 0.082 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.918 0.082 0.000
S61 Open wound of wrist and hand
0.916 0.084 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.915 0.085 0.000
I95.9 Hypotension, unspecified
0.912 0.088 0.000
C15-C26 Malignant neoplasms of digestive organs
0.911 0.089 0.000
I20.0 Unstable angina
0.910 0.090 0.000
S00 Superficial injury of head
0.909 0.091 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
L40-L45 Papulosquamous disorders
0.904 0.096 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.901 0.099 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
I21.4 Acute subendocardial myocardial infarction
0.881 0.119 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.880 0.120 0.000
Chapter VI Diseases of the nervous system
0.877 0.123 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.875 0.125 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
E78.5 Hyperlipidaemia, unspecified
0.870 0.130 0.000
L20-L30 Dermatitis and eczema
0.868 0.132 0.000
C91 Lymphoid leukaemia
0.865 0.135 0.000
E65-E68 Obesity and other hyperalimentation
0.864 0.136 0.000
T86 Failure and rejection of transplanted organs and tissues
0.864 0.136 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.862 0.138 0.000
L40 Psoriasis
0.860 0.140 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.856 0.144 0.000
M79.0 Rheumatism, unspecified
0.853 0.147 0.000
J00-J06 Acute upper respiratory infections
0.852 0.148 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.850 0.150 0.000
I95.1 Orthostatic hypotension
0.849 0.151 0.000
E11 Non-insulin-dependent diabetes mellitus
0.849 0.151 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.843 0.157 0.000
L03 Cellulitis
0.842 0.158 0.000
S61.0 Open wound of finger(s) without damage to nail
0.841 0.159 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.840 0.159 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.840 0.160 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.838 0.162 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.838 0.162 0.000
J09-J18 Influenza and pneumonia
0.837 0.163 0.000
M79.6 Pain in limb
0.837 0.163 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.836 0.164 0.000
A30-A49 Other bacterial diseases
0.835 0.165 0.000
S00.0 Superficial injury of scalp
0.831 0.169 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.830 0.170 0.000
Y43 Primarily systemic agents
0.830 0.170 0.000
M79.8 Other specified soft tissue disorders
0.829 0.171 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.829 0.171 0.000
I10-I15 Hypertensive diseases
0.827 0.173 0.000
M72 Fibroblastic disorders
0.825 0.175 0.000
V40-V49 Car occupant injured in transport accident
0.822 0.178 0.000
A00-A09 Intestinal infectious diseases
0.821 0.179 0.000
H65-H75 Diseases of middle ear and mastoid
0.818 0.182 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.817 0.183 0.000
M07 Psoriatic and enteropathic arthropathies
0.817 0.183 0.000
I05-I09 Chronic rheumatic heart diseases
0.816 0.184 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.815 0.185 0.000
L08 Other local infections of skin and subcutaneous tissue
0.811 0.189 0.000
E14 Unspecified diabetes mellitus
0.809 0.191 0.000
M13 Other arthritis
0.809 0.191 0.000
M91-M94 Chondropathies
0.807 0.193 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.804 0.196 0.000
T81 Complications of procedures, not elsewhere classified
0.802 0.198 0.000
I21.9 Acute myocardial infarction, unspecified
0.801 0.199 0.000
E10.3 With ophthalmic complications
0.799 0.201 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.799 0.201 0.000
C91.1 Chronic lymphocytic leukaemia
0.799 0.201 0.000
M65 Synovitis and tenosynovitis
0.796 0.204 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.795 0.205 0.000
S00.1 Contusion of eyelid and periocular area
0.795 0.205 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.793 0.207 0.000
S90-S99 Injuries to the ankle and foot
0.792 0.208 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.792 0.208 0.000
J30-J39 Other diseases of upper respiratory tract
0.791 0.209 0.000
I25.1 Atherosclerotic heart disease
0.791 0.209 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.790 0.210 0.000
C25 Malignant neoplasm of pancreas
0.788 0.212 0.000
I25.5 Ischaemic cardiomyopathy
0.786 0.213 0.000
E87.2 Acidosis
0.785 0.215 0.000
S01 Open wound of head
0.784 0.216 0.000
M06 Other rheumatoid arthritis
0.783 0.217 0.000
E83 Disorders of mineral metabolism
0.782 0.218 0.000
S02 Fracture of skull and facial bones
0.782 0.218 0.000
S60 Superficial injury of wrist and hand
0.780 0.220 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.778 0.222 0.000
M86-M90 Other osteopathies
0.777 0.223 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.777 0.223 0.000
J02 Acute pharyngitis
0.776 0.223 0.000
L40.5 Arthropathic psoriasis
0.776 0.224 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.775 0.225 0.000
L29 Pruritus
0.774 0.226 0.000
C51-C58 Malignant neoplasms of female genital organs
0.773 0.227 0.000
W00-W19 Falls
0.773 0.227 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.771 0.229 0.000
Chapter XXII Codes for special purposes
0.771 0.229 0.000
S70-S79 Injuries to the hip and thigh
0.771 0.229 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
E66 Obesity
0.766 0.234 0.000
I62 Other nontraumatic intracranial haemorrhage
0.766 0.234 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.763 0.237 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.763 0.237 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.761 0.239 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.760 0.240 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.760 0.240 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.757 0.243 0.000
L40.9 Psoriasis, unspecified
0.757 0.243 0.000
S61.8 Open wound of other parts of wrist and hand
0.754 0.246 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.752 0.248 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.751 0.249 0.000
Chapter XI Diseases of the digestive system
0.751 0.249 0.000
C18 Malignant neoplasm of colon
0.751 0.249 0.000
I71 Aortic aneurysm and dissection
0.750 0.250 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.750 0.250 0.000
S67 Crushing injury of wrist and hand
0.749 0.251 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.748 0.251 0.000
J18 Pneumonia, organism unspecified
0.748 0.252 0.000
I25.3 Aneurysm of heart
0.747 0.253 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.746 0.254 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.745 0.255 0.000
S50-S59 Injuries to the elbow and forearm
0.743 0.257 0.000
B35-B49 Mycoses
0.742 0.258 0.000
C90.0 Multiple myeloma
0.741 0.259 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.740 0.260 0.000
E13 Other specified diabetes mellitus
0.738 0.262 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.738 0.262 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.736 0.264 0.000
L03.8 Cellulitis of other sites
0.735 0.265 0.000
K80 Cholelithiasis
0.735 0.265 0.000
L50-L54 Urticaria and erythema
0.733 0.267 0.000
M20-M25 Other joint disorders
0.733 0.267 0.000
C20 Malignant neoplasm of rectum
0.732 0.268 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.732 0.268 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.731 0.269 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.730 0.270 0.000
Y43.3 Other antineoplastic drugs
0.729 0.271 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.729 0.271 0.000
T86.0 Bone-marrow transplant rejection
0.728 0.272 0.000
E88 Other metabolic disorders
0.728 0.272 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.727 0.273 0.000
M07.3 Other psoriatic arthropathies
0.726 0.274 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.726 0.274 0.000
C91.0 Acute lymphoblastic leukaemia
0.725 0.275 0.000
E20-E35 Disorders of other endocrine glands
0.724 0.276 0.000
M77 Other enthesopathies
0.724 0.276 0.000
M79.1 Myalgia
0.723 0.277 0.000
J02.9 Acute pharyngitis, unspecified
0.723 0.277 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.722 0.278 0.000
D50-D53 Nutritional anaemias
0.720 0.280 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.720 0.280 0.000
S64 Injury of nerves at wrist and hand level
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.719 0.280 0.000
A80-A89 Viral infections of the central nervous system
0.719 0.281 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.719 0.281 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
M11 Other crystal arthropathies
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I95.2 Hypotension due to drugs
0.717 0.283 0.000
E50-E64 Other nutritional deficiencies
0.716 0.284 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.716 0.284 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.715 0.285 0.000
A08 Viral and other specified intestinal infections
0.715 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.715 0.285 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
J34 Other disorders of nose and nasal sinuses
0.714 0.286 0.000
M80-M85 Disorders of bone density and structure
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
T18 Foreign body in alimentary tract
0.712 0.288 0.000
I61 Intracerebral haemorrhage
0.711 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
E11.5 With peripheral circulatory complications
0.711 0.289 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.711 0.289 0.000
A41 Other septicaemia
0.710 0.290 0.000
J20-J22 Other acute lower respiratory infections
0.710 0.290 0.000
E11.9 Without complications
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.707 0.293 0.000
I25.4 Coronary artery aneurysm
0.707 0.293 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.707 0.293 0.000
E85 Amyloidosis
0.707 0.293 0.000
E84 Cystic fibrosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.293 0.000
E74 Other disorders of carbohydrate metabolism
0.707 0.293 0.000
E73 Lactose intolerance
0.707 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.293 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.707 0.293 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.705 0.295 0.000
D60-D64 Aplastic and other anaemias
0.705 0.295 0.000
I99 Other and unspecified disorders of circulatory system
0.704 0.296 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.703 0.297 0.000
I69 Sequelae of cerebrovascular disease
0.702 0.298 0.000
E10.8 With unspecified complications
0.701 0.299 0.000
E10.7 With multiple complications
0.701 0.299 0.000
E10.6 With other specified complications
0.701 0.299 0.000
E10.5 With peripheral circulatory complications
0.701 0.299 0.000
E10.2 With renal complications
0.701 0.299 0.000
E10.0 With coma
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.700 0.300 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.700 0.300 0.000
B65-B83 Helminthiases
0.700 0.300 0.000
B50-B64 Protozoal diseases
0.700 0.300 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.300 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.700 0.300 0.000
A75-A79 Rickettsioses
0.700 0.300 0.000
A70-A74 Other diseases caused by chlamydiae
0.700 0.300 0.000
A65-A69 Other spirochaetal diseases
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
A20-A28 Certain zoonotic bacterial diseases
0.700 0.300 0.000
A15-A19 Tuberculosis
0.700 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.300 0.000
E10.4 With neurological complications
0.699 0.301 0.000
G90-G99 Other disorders of the nervous system
0.699 0.301 0.000
L29.0 Pruritus ani
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
H73 Other disorders of tympanic membrane
0.698 0.302 0.000
J00 Acute nasopharyngitis [common cold]
0.698 0.302 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.698 0.302 0.000
G40-G47 Episodic and paroxysmal disorders
0.697 0.303 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
M76 Enthesopathies of lower limb, excluding foot
0.697 0.303 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.697 0.303 0.000
I63.8 Other cerebral infarction
0.697 0.303 0.000
Y59 Other and unspecified vaccines and biological substances
0.696 0.304 0.000
Y58 Bacterial vaccines
0.696 0.304 0.000
Y57 Other and unspecified drugs and medicaments
0.696 0.304 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.696 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.696 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.696 0.304 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
Y48 Anaesthetics and therapeutic gases
0.696 0.304 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.696 0.304 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
E87.0 Hyperosmolality and hypernatraemia
0.696 0.304 0.000
S69 Other and unspecified injuries of wrist and hand
0.695 0.305 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.695 0.305 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.695 0.305 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.695 0.305 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.695 0.305 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.695 0.305 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.695 0.305 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.306 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.694 0.306 0.000
E14.9 Without complications
0.694 0.306 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.694 0.306 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.693 0.306 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.693 0.307 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.693 0.307 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.693 0.307 0.000
E78.8 Other disorders of lipoprotein metabolism
0.693 0.307 0.000
M79.69 Pain in limb (Site unspecified)
0.692 0.308 0.000
I10 Essential (primary) hypertension
0.692 0.308 0.000
Y40 Systemic antibiotics
0.692 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
S62 Fracture at wrist and hand level
0.691 0.309 0.000
E86 Volume depletion
0.691 0.309 0.000
C25.0 Head of pancreas
0.690 0.309 0.000
M05 Seropositive rheumatoid arthritis
0.690 0.310 0.000
I26 Pulmonary embolism
0.690 0.310 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
H90-H95 Other disorders of ear
0.689 0.311 0.000
S00.9 Superficial injury of head, part unspecified
0.689 0.311 0.000
S08 Traumatic amputation of part of head
0.689 0.311 0.000
S07 Crushing injury of head
0.689 0.311 0.000
S05 Injury of eye and orbit
0.689 0.311 0.000
S04 Injury of cranial nerves
0.689 0.311 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.689 0.311 0.000
S06 Intracranial injury
0.689 0.311 0.000
M79.5 Residual foreign body in soft tissue
0.689 0.311 0.000
I95.8 Other hypotension
0.687 0.312 0.000
I95.0 Idiopathic hypotension
0.687 0.312 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.687 0.313 0.000
M06.0 Seronegative rheumatoid arthritis
0.687 0.313 0.000
S00.3 Superficial injury of nose
0.687 0.313 0.000
E89.3 Postprocedural hypopituitarism
0.687 0.313 0.000
S40-S49 Injuries to the shoulder and upper arm
0.686 0.314 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.685 0.315 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.685 0.315 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.684 0.316 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.684 0.316 0.000
Y98 Lifestyle-related condition
0.684 0.316 0.000
Y97 Environmental-pollution-related condition
0.684 0.316 0.000
Y96 Work-related condition
0.684 0.316 0.000
I67 Other cerebrovascular diseases
0.684 0.316 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.683 0.317 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.681 0.319 0.000
M79.9 Soft tissue disorder, unspecified
0.681 0.319 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.681 0.319 0.000
M79.3 Panniculitis, unspecified
0.681 0.319 0.000
M79.2 Neuralgia and neuritis, unspecified
0.681 0.319 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.681 0.319 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.681 0.319 0.000
S68 Traumatic amputation of wrist and hand
0.681 0.319 0.000
Chapter VII Diseases of the eye and adnexa
0.681 0.319 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
W20-W49 Exposure to inanimate mechanical forces
0.680 0.320 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.680 0.320 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.680 0.320 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.680 0.320 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.680 0.320 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.680 0.320 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.680 0.320 0.000
M79.67 Pain in limb (Ankle and foot)
0.680 0.320 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.679 0.321 0.000
J30 Vasomotor and allergic rhinitis
0.678 0.322 0.000
E66.8 Other obesity
0.677 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
S20-S29 Injuries to the thorax
0.676 0.324 0.000
S91 Open wound of ankle and foot
0.676 0.324 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.675 0.325 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.675 0.325 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.675 0.325 0.000
L03.9 Cellulitis, unspecified
0.675 0.325 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.674 0.326 0.000
T86.1 Kidney transplant failure and rejection
0.674 0.326 0.000
K86 Other diseases of pancreas
0.674 0.326 0.000
H80-H83 Diseases of inner ear
0.673 0.327 0.000
I08 Multiple valve diseases
0.673 0.327 0.000
M94 Other disorders of cartilage
0.673 0.327 0.000
E89.0 Postprocedural hypothyroidism
0.672 0.328 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.670 0.330 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.670 0.330 0.000
E87.6 Hypokalaemia
0.669 0.331 0.000
S32 Fracture of lumbar spine and pelvis
0.669 0.331 0.000
I22 Subsequent myocardial infarction
0.669 0.331 0.000
B15-B19 Viral hepatitis
0.668 0.331 0.000
S61.1 Open wound of finger(s) with damage to nail
0.668 0.332 0.000
J18.9 Pneumonia, unspecified
0.667 0.333 0.000
M13.9 Arthritis, unspecified
0.667 0.333 0.000
L05 Pilonidal cyst
0.666 0.334 0.000
H66 Suppurative and unspecified otitis media
0.666 0.334 0.000
L03.2 Cellulitis of face
0.665 0.335 0.000
C56 Malignant neoplasm of ovary
0.664 0.336 0.000
M79.7 Fibromyalgia
0.664 0.336 0.000
E11.4 With neurological complications
0.664 0.336 0.000
H60-H62 Diseases of external ear
0.664 0.336 0.000
E16 Other disorders of pancreatic internal secretion
0.663 0.337 0.000
I60 Subarachnoid haemorrhage
0.663 0.337 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.663 0.337 0.000
I24.1 Dressler's syndrome
0.663 0.337 0.000
C81 Hodgkin's disease
0.662 0.337 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.662 0.338 0.000
I72 Other aneurysm
0.661 0.339 0.000
D72 Other disorders of white blood cells
0.660 0.340 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.340 0.000
I27 Other pulmonary heart diseases
0.660 0.340 0.000
I20.1 Angina pectoris with documented spasm
0.659 0.341 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.659 0.341 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.658 0.341 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.658 0.341 0.000
Y52.7 Peripheral vasodilators
0.658 0.341 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.658 0.341 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.658 0.341 0.000
Y52.1 Calcium-channel blockers
0.658 0.341 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.658 0.341 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.658 0.342 0.000
C95 Leukaemia of unspecified cell type
0.658 0.342 0.000
C94 Other leukaemias of specified cell type
0.658 0.342 0.000
C93 Monocytic leukaemia
0.658 0.342 0.000
C88 Malignant immunoproliferative diseases
0.658 0.342 0.000
C86 Other specified types of T/NK-cell lymphoma
0.658 0.342 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.658 0.342 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.657 0.343 0.000
L27 Dermatitis due to substances taken internally
0.657 0.343 0.000
S61.7 Multiple open wounds of wrist and hand
0.657 0.343 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.657 0.343 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.656 0.344 0.000
Y44 Agents primarily affecting blood constituents
0.655 0.345 0.000
M45-M49 Spondylopathies
0.654 0.346 0.000
M13.0 Polyarthritis, unspecified
0.654 0.346 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.653 0.347 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.653 0.347 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.653 0.347 0.000
C21 Malignant neoplasm of anus and anal canal
0.653 0.347 0.000
C17 Malignant neoplasm of small intestine
0.653 0.347 0.000
C23 Malignant neoplasm of gallbladder
0.653 0.347 0.000
T82.1 Mechanical complication of cardiac electronic device
0.653 0.347 0.000
J95-J99 Other diseases of the respiratory system
0.652 0.348 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.652 0.348 0.000
S00.7 Multiple superficial injuries of head
0.652 0.348 0.000
S00.5 Superficial injury of lip and oral cavity
0.652 0.348 0.000
S00.4 Superficial injury of ear
0.652 0.348 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.652 0.348 0.000
L04 Acute lymphadenitis
0.652 0.348 0.000
L01 Impetigo
0.652 0.348 0.000
L00 Staphylococcal scalded skin syndrome
0.652 0.348 0.000
V48 Car occupant injured in noncollision transport accident
0.651 0.349 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.651 0.349 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.651 0.349 0.000
D37.4 Colon
0.650 0.350 0.000
T92 Sequelae of injuries of upper limb
0.650 0.350 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.650 0.350 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.649 0.350 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.649 0.351 0.000
S01.3 Open wound of ear
0.649 0.351 0.000
L44 Other papulosquamous disorders
0.648 0.352 0.000
L41 Parapsoriasis
0.648 0.352 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.648 0.352 0.000
L42 Pityriasis rosea
0.648 0.352 0.000
E10.1 With ketoacidosis
0.648 0.352 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.648 0.352 0.000
Y84.6 Urinary catheterisation
0.647 0.353 0.000
L03.3 Cellulitis of trunk
0.647 0.353 0.000
E78.6 Lipoprotein deficiency
0.646 0.354 0.000
E78.4 Other hyperlipidaemia
0.646 0.354 0.000
E78.3 Hyperchylomicronaemia
0.646 0.354 0.000
E78.2 Mixed hyperlipidaemia
0.646 0.354 0.000
E78.1 Pure hyperglyceridaemia
0.646 0.354 0.000
S60.8 Other superficial injuries of wrist and hand
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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