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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76796201
log Bayes Factor = 14.1948
Chromosome 12   position 23,091,755  (GRCh37) Explore rs76796201 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
0.995 0.005 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.980 0.020 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
Z92 Personal history of medical treatment
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
E10-E14 Diabetes mellitus
0.965 0.035 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.963 0.037 0.000
Z92.3 Personal history of irradiation
0.958 0.042 0.000
Z93 Artificial opening status
0.958 0.042 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.957 0.043 0.000
M70-M79 Other soft tissue disorders
0.950 0.050 0.000
H25-H28 Disorders of lens
0.944 0.056 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.943 0.057 0.000
M47 Spondylosis
0.938 0.062 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.936 0.064 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.935 0.065 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.924 0.076 0.000
H43-H45 Disorders of vitreous body and globe
0.915 0.085 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.914 0.086 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.913 0.087 0.000
H04 Disorders of lachrymal system
0.910 0.090 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
E10 Insulin-dependent diabetes mellitus
0.903 0.096 0.000
H02 Other disorders of eyelid
0.903 0.097 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.903 0.097 0.000
Z96 Presence of other functional implants
0.902 0.098 0.000
M65-M68 Disorders of synovium and tendon
0.896 0.104 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.892 0.108 0.000
M47.9 Spondylosis, unspecified
0.891 0.109 0.000
H53-H54 Visual disturbances and blindness
0.888 0.112 0.000
Z72 Problems related to lifestyle
0.886 0.114 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.880 0.120 0.000
H26 Other cataract
0.878 0.122 0.000
Z93.2 Ileostomy status
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.872 0.128 0.000
E10.9 Without complications
0.867 0.133 0.000
M15-M19 Arthrosis
0.865 0.135 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.864 0.136 0.000
E00-E07 Disorders of thyroid gland
0.862 0.138 0.000
M79.6 Pain in limb
0.862 0.138 0.000
H44 Disorders of globe
0.859 0.141 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.858 0.142 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.856 0.144 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.856 0.144 0.000
M46 Other inflammatory spondylopathies
0.853 0.147 0.000
E14 Unspecified diabetes mellitus
0.852 0.148 0.000
Chapter II Neoplasms
0.851 0.149 0.000
M20-M25 Other joint disorders
0.849 0.151 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.847 0.153 0.000
Z93.3 Colostomy status
0.844 0.156 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.840 0.160 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.837 0.163 0.000
M79.8 Other specified soft tissue disorders
0.836 0.164 0.000
H02.3 Blepharochalasis
0.836 0.164 0.000
Chapter I Certain infectious and parasitic diseases
0.834 0.166 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.834 0.166 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.832 0.168 0.000
Z83 Family history of other specific disorders
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.828 0.172 0.000
O36 Maternal care for other known or suspected foetal problems
0.828 0.172 0.000
Z96.0 Presence of urogenital implants
0.828 0.172 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.823 0.177 0.000
H54 Blindness and low vision
0.820 0.180 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.820 0.180 0.000
M65 Synovitis and tenosynovitis
0.819 0.181 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.818 0.182 0.000
H44.2 Degenerative myopia
0.818 0.182 0.000
E11 Non-insulin-dependent diabetes mellitus
0.816 0.184 0.000
S90-S99 Injuries to the ankle and foot
0.815 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
Z96.1 Presence of intraocular lens
0.815 0.185 0.000
M79.66 Pain in limb (Lower leg)
0.813 0.187 0.000
T39.1 4-Aminophenol derivatives
0.813 0.187 0.000
W00-W19 Falls
0.810 0.190 0.000
Z92.0 Personal history of contraception
0.808 0.192 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
M40-M43 Deforming dorsopathies
0.807 0.193 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.806 0.194 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.805 0.195 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.804 0.196 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.804 0.196 0.000
Z72.1 Alcohol use
0.802 0.198 0.000
M17 Gonarthrosis [arthrosis of knee]
0.801 0.199 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.801 0.199 0.000
H10-H13 Disorders of conjunctiva
0.800 0.199 0.000
H55-H59 Other disorders of eye and adnexa
0.799 0.201 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.799 0.201 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.797 0.203 0.000
Chapter X Diseases of the respiratory system
0.796 0.204 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.794 0.206 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.794 0.206 0.000
D00-D09 In situ neoplasms
0.792 0.208 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.789 0.211 0.000
E14.9 Without complications
0.785 0.215 0.000
G30-G32 Other degenerative diseases of the nervous system
0.785 0.215 0.000
Z72.0 Tobacco use
0.783 0.217 0.000
H04.1 Other disorders of lachrymal gland
0.782 0.218 0.000
E04 Other non-toxic goitre
0.781 0.219 0.000
M79.1 Myalgia
0.781 0.219 0.000
R07 Pain in throat and chest
0.780 0.220 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.780 0.220 0.000
M60-M63 Disorders of muscles
0.779 0.221 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.779 0.221 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.778 0.222 0.000
R50-R69 General symptoms and signs
0.778 0.222 0.000
T79-T79 Certain early complications of trauma
0.777 0.223 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.775 0.225 0.000
Y44 Agents primarily affecting blood constituents
0.774 0.226 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.771 0.229 0.000
M17.1 Other primary gonarthrosis
0.771 0.229 0.000
H30-H36 Disorders of choroid and retina
0.770 0.230 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.770 0.230 0.000
Y40 Systemic antibiotics
0.770 0.230 0.000
H25 Senile cataract
0.770 0.230 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.769 0.231 0.000
H05 Disorders of orbit
0.768 0.232 0.000
O00-O08 Pregnancy with abortive outcome
0.767 0.233 0.000
M79.67 Pain in limb (Ankle and foot)
0.766 0.234 0.000
H26.4 After-cataract
0.766 0.234 0.000
O80-O84 Delivery
0.765 0.235 0.000
Y43 Primarily systemic agents
0.764 0.236 0.000
H26.8 Other specified cataract
0.764 0.236 0.000
Z02 Examination and encounter for administrative purposes
0.764 0.236 0.000
O36.5 Maternal care for poor foetal growth
0.763 0.237 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.763 0.237 0.000
H50 Other strabismus
0.763 0.237 0.000
L40-L45 Papulosquamous disorders
0.761 0.239 0.000
M65.3 Trigger finger
0.760 0.240 0.000
M48 Other spondylopathies
0.759 0.241 0.000
O60-O75 Complications of labour and delivery
0.758 0.242 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.757 0.243 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
E20-E35 Disorders of other endocrine glands
0.756 0.244 0.000
C15-C26 Malignant neoplasms of digestive organs
0.756 0.244 0.000
R51 Headache
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
H02.1 Ectropion of eyelid
0.754 0.246 0.000
G58 Other mononeuropathies
0.753 0.247 0.000
H18 Other disorders of cornea
0.752 0.248 0.000
Z83.3 Family history of diabetes mellitus
0.752 0.248 0.000
S70-S79 Injuries to the hip and thigh
0.751 0.249 0.000
R21 Rash and other nonspecific skin eruption
0.751 0.249 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.751 0.249 0.000
E04.9 Non-toxic goitre, unspecified
0.749 0.251 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.748 0.252 0.000
V80-V89 Other land transport accidents
0.747 0.253 0.000
A30-A49 Other bacterial diseases
0.747 0.253 0.000
R47-R49 Symptoms and signs involving speech and voice
0.746 0.254 0.000
D05 Carcinoma in situ of breast
0.746 0.254 0.000
M76 Enthesopathies of lower limb, excluding foot
0.745 0.255 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.743 0.256 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.743 0.257 0.000
M47.8 Other spondylosis
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
M23 Internal derangement of knee
0.741 0.259 0.000
R02 Gangrene, not elsewhere classified
0.740 0.260 0.000
S00-S09 Injuries to the head
0.739 0.261 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.739 0.261 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.738 0.262 0.000
Z93.0 Tracheostomy status
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.738 0.262 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.737 0.263 0.000
Z03.4 Observation for suspected myocardial infarction
0.735 0.265 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.734 0.266 0.000
E11.4 With neurological complications
0.734 0.266 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.733 0.267 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.732 0.267 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.731 0.269 0.000
E16 Other disorders of pancreatic internal secretion
0.731 0.269 0.000
M91-M94 Chondropathies
0.730 0.270 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.730 0.270 0.000
E65-E68 Obesity and other hyperalimentation
0.730 0.270 0.000
S80-S89 Injuries to the knee and lower leg
0.728 0.272 0.000
G51 Facial nerve disorders
0.728 0.272 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.726 0.274 0.000
J90-J94 Other diseases of pleura
0.725 0.275 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.724 0.276 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.724 0.276 0.000
Z93.6 Other artificial openings of urinary tract status
0.723 0.277 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.720 0.280 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.719 0.281 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.281 0.000
M65.34 Trigger finger-Hand
0.718 0.282 0.000
M47.2 Other spondylosis with radiculopathy
0.718 0.282 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
O41 Other disorders of amniotic fluid and membranes
0.715 0.285 0.000
H16 Keratitis
0.713 0.287 0.000
L40 Psoriasis
0.713 0.287 0.000
M84 Disorders of continuity of bone
0.713 0.287 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
O40 Polyhydramnios
0.711 0.289 0.000
M47.86 Other spondylosis (Lumbar region)
0.711 0.289 0.000
G90-G99 Other disorders of the nervous system
0.710 0.290 0.000
H04.2 Epiphora
0.710 0.290 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.710 0.290 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.710 0.290 0.000
Z02.8 Other examinations for administrative purposes
0.710 0.290 0.000
L50-L54 Urticaria and erythema
0.709 0.291 0.000
O44 Placenta praevia
0.709 0.291 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.292 0.000
Z73 Problems related to life-management difficulty
0.707 0.293 0.000
G62 Other polyneuropathies
0.707 0.293 0.000
G59.0 Diabetic mononeuropathy
0.706 0.293 0.000
M50-M54 Other dorsopathies
0.706 0.294 0.000
H54.4 Blindness, one eye
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
S10-S19 Injuries to the neck
0.705 0.295 0.000
H02.8 Other specified disorders of eyelid
0.705 0.295 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.704 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.704 0.296 0.000
M05-M14 Inflammatory polyarthropathies
0.704 0.296 0.000
M35 Other systemic involvement of connective tissue
0.703 0.297 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.702 0.298 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.699 0.300 0.000
M45 Ankylosing spondylitis
0.699 0.301 0.000
H54.0 Blindness, both eyes
0.698 0.302 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
H27 Other disorders of lens
0.695 0.305 0.000
Z92.9 Personal history of medical treatment, unspecified
0.695 0.305 0.000
Z92.5 Personal history of rehabilitation measures
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.694 0.306 0.000
O02 Other abnormal products of conception
0.694 0.306 0.000
H40-H42 Glaucoma
0.693 0.307 0.000
E40-E46 Malnutrition
0.692 0.308 0.000
E13 Other specified diabetes mellitus
0.692 0.308 0.000
E12 Malnutrition-related diabetes mellitus
0.692 0.308 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.691 0.309 0.000
G20-G26 Extrapyramidal and movement disorders
0.691 0.309 0.000
O85-O92 Complications predominantly related to the puerperium
0.690 0.310 0.000
H35 Other retinal disorders
0.690 0.310 0.000
M23.3 Other meniscus derangements
0.690 0.310 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.689 0.311 0.000
C43 Malignant melanoma of skin
0.688 0.312 0.000
Z93.9 Artificial opening status, unspecified
0.687 0.313 0.000
Z93.8 Other artificial opening status
0.687 0.313 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.687 0.313 0.000
B35-B49 Mycoses
0.686 0.314 0.000
M87 Osteonecrosis
0.685 0.314 0.000
R23 Other skin changes
0.685 0.315 0.000
M43 Other deforming dorsopathies
0.685 0.315 0.000
T40.2 Other opioids
0.685 0.315 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.685 0.315 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.684 0.316 0.000
T51 Toxic effect of alcohol
0.684 0.316 0.000
M85 Other disorders of bone density and structure
0.684 0.316 0.000
Z92.8 Personal history of other medical treatment
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.682 0.318 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.682 0.318 0.000
R07.1 Chest pain on breathing
0.682 0.318 0.000
S50-S59 Injuries to the elbow and forearm
0.682 0.318 0.000
Q50-Q56 Congenital malformations of genital organs
0.681 0.319 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.319 0.000
Z90.1 Acquired absence of breast(s)
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
G61 Inflammatory polyneuropathy
0.679 0.321 0.000
Q60-Q64 Congenital malformations of the urinary system
0.679 0.321 0.000
H00 Hordeolum and chalazion
0.678 0.322 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.678 0.322 0.000
H50.1 Divergent concomitant strabismus
0.678 0.322 0.000
C18 Malignant neoplasm of colon
0.678 0.322 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.677 0.323 0.000
G54 Nerve root and plexus disorders
0.676 0.324 0.000
G52 Disorders of other cranial nerves
0.676 0.324 0.000
W07 Fall involving chair
0.675 0.325 0.000
Y41.5 Antiviral drugs
0.675 0.325 0.000
Y44.2 Anticoagulants
0.674 0.326 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.674 0.326 0.000
M80 Osteoporosis with pathological fracture
0.673 0.326 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.673 0.327 0.000
M17.0 Primary gonarthrosis, bilateral
0.673 0.327 0.000
M47.1 Other spondylosis with myelopathy
0.673 0.327 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.673 0.327 0.000
M31 Other necrotising vasculopathies
0.673 0.327 0.000
H21 Other disorders of iris and ciliary body
0.672 0.327 0.000
S80 Superficial injury of lower leg
0.672 0.327 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
O48 Prolonged pregnancy
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.671 0.329 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.671 0.329 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.671 0.329 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.671 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.671 0.329 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
T36 Poisoning by systemic antibiotics
0.671 0.329 0.000
Z76 Persons encountering health services in other circumstances
0.670 0.330 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.670 0.330 0.000
O72 Postpartum haemorrhage
0.670 0.330 0.000
H02.6 Xanthelasma of eyelid
0.669 0.331 0.000
M71 Other bursopathies
0.668 0.332 0.000
O36.4 Maternal care for intra-uterine death
0.668 0.332 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
Z93.1 Gastrostomy status
0.666 0.334 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.666 0.334 0.000
T59 Toxic effect of other gases, fumes and vapours
0.666 0.334 0.000
A41 Other septicaemia
0.665 0.335 0.000
C15 Malignant neoplasm of oesophagus
0.665 0.335 0.000
Q21 Congenital malformations of cardiac septa
0.665 0.335 0.000
D10-D36 Benign neoplasms
0.664 0.336 0.000
M77 Other enthesopathies
0.664 0.336 0.000
M79.9 Soft tissue disorder, unspecified
0.663 0.337 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.663 0.337 0.000
M79.3 Panniculitis, unspecified
0.663 0.337 0.000
M79.2 Neuralgia and neuritis, unspecified
0.663 0.337 0.000
E10.3 With ophthalmic complications
0.663 0.337 0.000
J93 Pneumothorax
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.659 0.341 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.658 0.342 0.000
Z43 Attention to artificial openings
0.657 0.343 0.000
Y43.3 Other antineoplastic drugs
0.657 0.343 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.656 0.344 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.656 0.344 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.655 0.344 0.000
Y58 Bacterial vaccines
0.655 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.655 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.344 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.655 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.655 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.655 0.344 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.655 0.344 0.000
Y48 Anaesthetics and therapeutic gases
0.655 0.344 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.655 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.655 0.344 0.000
E16.2 Hypoglycaemia, unspecified
0.655 0.345 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.654 0.346 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.654 0.346 0.000
O30 Multiple gestation
0.654 0.346 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.654 0.346 0.000
H25.1 Senile nuclear cataract
0.654 0.346 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.654 0.346 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.654 0.346 0.000
C43.5 Malignant melanoma of trunk
0.653 0.347 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.653 0.347 0.000
H06.2 Dysthyroid exophthalmos
0.653 0.347 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.652 0.347 0.000
O47 False labour
0.652 0.347 0.000
H04.9 Disorder of lachrymal system, unspecified
0.652 0.348 0.000
H04.8 Other disorders of lachrymal system
0.652 0.348 0.000
H04.6 Other changes in lachrymal passages
0.652 0.348 0.000
H04.4 Chronic inflammation of lachrymal passages
0.652 0.348 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.652 0.348 0.000
H04.0 Dacryoadenitis
0.652 0.348 0.000
T93 Sequelae of injuries of lower limb
0.652 0.348 0.000
M67 Other disorders of synovium and tendon
0.652 0.348 0.000
O43 Placental disorders
0.651 0.349 0.000
R54 Senility
0.651 0.349 0.000
H57 Other disorders of eye and adnexa
0.651 0.349 0.000
R05 Cough
0.651 0.349 0.000
H11 Other disorders of conjunctiva
0.651 0.349 0.000
H49 Paralytic strabismus
0.650 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q80-Q89 Other congenital malformations
0.650 0.350 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.350 0.000
M79.5 Residual foreign body in soft tissue
0.650 0.350 0.000
Z96.8 Presence of other specified functional implants
0.650 0.350 0.000
G50 Disorders of trigeminal nerve
0.649 0.350 0.000
H50.2 Vertical strabismus
0.649 0.350 0.000
G60 Hereditary and idiopathic neuropathy
0.649 0.351 0.000
H26.9 Cataract, unspecified
0.648 0.352 0.000
M79.19 Myalgia (Site unspecified)
0.648 0.352 0.000
D50-D53 Nutritional anaemias
0.648 0.352 0.000
E10.8 With unspecified complications
0.648 0.352 0.000
E10.7 With multiple complications
0.648 0.352 0.000
E10.6 With other specified complications
0.648 0.352 0.000
E10.5 With peripheral circulatory complications
0.648 0.352 0.000
E10.4 With neurological complications
0.648 0.352 0.000
E10.2 With renal complications
0.648 0.352 0.000
E10.0 With coma
0.648 0.352 0.000
D22 Melanocytic naevi
0.648 0.352 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.648 0.352 0.000
H02.2 Lagophthalmos
0.648 0.352 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.647 0.353 0.000
Z96.9 Presence of functional implant, unspecified
0.647 0.353 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.647 0.353 0.000
Z96.4 Presence of endocrine implants
0.647 0.353 0.000
Z96.3 Presence of artificial larynx
0.647 0.353 0.000
Z96.2 Presence of otological and audiological implants
0.647 0.353 0.000
Y40.8 Other systemic antibiotics
0.646 0.354 0.000
R56 Convulsions, not elsewhere classified
0.646 0.354 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
Z60 Problems related to social environment
0.645 0.355 0.000
M25 Other joint disorders, not elsewhere classified
0.645 0.355 0.000
M16 Coxarthrosis [arthrosis of hip]
0.644 0.356 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.643 0.357 0.000
Y84.8 Other medical procedures
0.643 0.357 0.000
Z93.5 Cystostomy status
0.643 0.357 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.643 0.357 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.643 0.357 0.000
G83 Other paralytic syndromes
0.642 0.357 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.642 0.358 0.000
M66 Spontaneous rupture of synovium and tendon
0.642 0.358 0.000
M81 Osteoporosis without pathological fracture
0.642 0.358 0.000
M19 Other arthrosis
0.640 0.360 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.640 0.360 0.000
O45 Premature separation of placenta [abruptio placentae]
0.640 0.360 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.640 0.360 0.000
O33 Maternal care for known or suspected disproportion
0.640 0.360 0.000
O31 Complications specific to multiple gestation
0.640 0.360 0.000
H43 Disorders of vitreous body
0.639 0.361 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.639 0.361 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.639 0.361 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.639 0.361 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.639 0.361 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.639 0.361 0.000
M72 Fibroblastic disorders
0.638 0.362 0.000
H35.8 Other specified retinal disorders
0.638 0.362 0.000
Z53.9 Procedure not carried out, unspecified reason
0.638 0.362 0.000
M21 Other acquired deformities of limbs
0.637 0.363 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.637 0.363 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.636 0.363 0.000
O36.8 Maternal care for other specified foetal problems
0.636 0.364 0.000
J90 Pleural effusion, not elsewhere classified
0.636 0.364 0.000
Z72.9 Problem related to lifestyle, unspecified
0.635 0.364 0.000
Z72.8 Other problems related to lifestyle
0.635 0.364 0.000
Z72.6 Gambling and betting
0.635 0.364 0.000
Z72.5 High-risk sexual behaviour
0.635 0.364 0.000
Z72.4 Inappropriate diet and eating habits
0.635 0.364 0.000
Z72.3 Lack of physical exercise
0.635 0.364 0.000
Z72.2 Drug use
0.635 0.364 0.000
O80 Single spontaneous delivery
0.635 0.365 0.000
M79.7 Fibromyalgia
0.635 0.365 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.634 0.366 0.000
Z75 Problems related to medical facilities and other health care
0.634 0.366 0.000
S92 Fracture of foot, except ankle
0.633 0.367 0.000
R47 Speech disturbances, not elsewhere classified
0.633 0.367 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
W18 Other fall on same level
0.632 0.368 0.000
R52 Pain, not elsewhere classified
0.632 0.368 0.000
E11.9 Without complications
0.632 0.368 0.000
M79.64 Pain in limb (Hand)
0.631 0.369 0.000
H54.7 Unspecified visual loss
0.631 0.369 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.631 0.369 0.000
S32 Fracture of lumbar spine and pelvis
0.631 0.369 0.000
T40.4 Other synthetic narcotics
0.631 0.369 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.631 0.369 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.631 0.369 0.000
H17 Corneal scars and opacities
0.631 0.369 0.000
H15 Disorders of sclera
0.631 0.369 0.000
S90 Superficial injury of ankle and foot
0.629 0.370 0.000
H02.4 Ptosis of eyelid
0.629 0.370 0.000
H26.3 Drug-induced cataract
0.629 0.371 0.000
H26.2 Complicated cataract
0.629 0.371 0.000
H26.1 Traumatic cataract
0.629 0.371 0.000
H26.0 Infantile, juvenile and presenile cataract
0.629 0.371 0.000
S02 Fracture of skull and facial bones
0.629 0.371 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.629 0.371 0.000
Z90.8 Acquired absence of other organs
0.628 0.372 0.000
A80-A89 Viral infections of the central nervous system
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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