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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77048935
log Bayes Factor = 15.1563
Chromosome 9   position 114,316,981  (GRCh37) Explore rs77048935 on Ensembl!
Variant rs77048935 is part of Cluster X0203

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.996 0.004 0.000
F10.2 Dependence syndrome
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
K92 Other diseases of digestive system
0.993 0.007 0.000
C60-C63 Malignant neoplasms of male genital organs
0.983 0.017 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.980 0.020 0.000
F10.1 Harmful use
0.976 0.024 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.971 0.029 0.000
C61 Malignant neoplasm of prostate
0.970 0.030 0.000
K92.0 Haematemesis
0.967 0.033 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.964 0.036 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.957 0.043 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.949 0.051 0.000
M20-M25 Other joint disorders
0.945 0.055 0.000
I21 Acute myocardial infarction
0.944 0.056 0.000
Chapter XXI Factors influencing health status and contact with health services
0.943 0.057 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.934 0.066 0.000
C15-C26 Malignant neoplasms of digestive organs
0.934 0.066 0.000
Chapter VII Diseases of the eye and adnexa
0.932 0.068 0.000
K92.1 Melaena
0.931 0.069 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.929 0.071 0.000
F10.0 Acute intoxication
0.928 0.072 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.927 0.073 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.922 0.078 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.916 0.084 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.908 0.092 0.000
H30-H36 Disorders of choroid and retina
0.902 0.098 0.000
S50-S59 Injuries to the elbow and forearm
0.901 0.099 0.000
S20-S29 Injuries to the thorax
0.901 0.099 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.900 0.100 0.000
I25.2 Old myocardial infarction
0.898 0.102 0.000
K55-K64 Other diseases of intestines
0.898 0.102 0.000
K70-K77 Diseases of liver
0.897 0.103 0.000
Z51 Other medical care
0.894 0.106 0.000
I21.9 Acute myocardial infarction, unspecified
0.891 0.109 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.891 0.109 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.890 0.110 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.884 0.116 0.000
H33 Retinal detachments and breaks
0.881 0.119 0.000
M22 Disorders of patella
0.878 0.122 0.000
R19.4 Change in bowel habit
0.878 0.122 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.869 0.131 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.869 0.131 0.000
T66-T78 Other and unspecified effects of external causes
0.867 0.133 0.000
K62 Other diseases of anus and rectum
0.865 0.135 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.855 0.145 0.000
M20 Acquired deformities of fingers and toes
0.854 0.146 0.000
C78.7 Secondary malignant neoplasm of liver
0.850 0.150 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.847 0.153 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.846 0.154 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.845 0.155 0.000
Chapter X Diseases of the respiratory system
0.843 0.157 0.000
Y57 Other and unspecified drugs and medicaments
0.837 0.163 0.000
K65-K67 Diseases of peritoneum
0.836 0.164 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.835 0.165 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.835 0.165 0.000
Z51.5 Palliative care
0.834 0.166 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.829 0.171 0.000
Z46 Fitting and adjustment of other devices
0.828 0.172 0.000
S52 Fracture of forearm
0.827 0.173 0.000
F41 Other anxiety disorders
0.826 0.174 0.000
K62.5 Haemorrhage of anus and rectum
0.824 0.176 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.821 0.179 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.820 0.180 0.000
F10.3 Withdrawal state
0.820 0.180 0.000
K08 Other disorders of teeth and supporting structures
0.820 0.180 0.000
K59 Other functional intestinal disorders
0.819 0.181 0.000
T82.3 Mechanical complication of other vascular grafts
0.818 0.182 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.815 0.185 0.000
S70-S79 Injuries to the hip and thigh
0.813 0.187 0.000
K92.9 Disease of digestive system, unspecified
0.812 0.188 0.000
Z45 Adjustment and management of implanted device
0.812 0.188 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.808 0.192 0.000
C50-C50 Malignant neoplasm of breast
0.807 0.193 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.807 0.193 0.000
F10.4 Withdrawal state with delirium
0.806 0.194 0.000
H33.3 Retinal breaks without detachment
0.804 0.196 0.000
K90 Intestinal malabsorption
0.802 0.198 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.801 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.798 0.202 0.000
Z50 Care involving use of rehabilitation procedures
0.797 0.203 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.797 0.203 0.000
I71 Aortic aneurysm and dissection
0.795 0.205 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.795 0.205 0.000
Z51.1 Chemotherapy session for neoplasm
0.795 0.205 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.795 0.205 0.000
Z43 Attention to artificial openings
0.794 0.206 0.000
S00-S09 Injuries to the head
0.792 0.208 0.000
I77 Other disorders of arteries and arterioles
0.790 0.210 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.790 0.210 0.000
W00-W19 Falls
0.790 0.210 0.000
F45 Somatoform disorders
0.784 0.216 0.000
I20 Angina pectoris
0.783 0.217 0.000
J90-J94 Other diseases of pleura
0.782 0.218 0.000
M22.2 Patellofemoral disorders
0.781 0.219 0.000
M50-M54 Other dorsopathies
0.781 0.219 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.780 0.220 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.780 0.220 0.000
C22.0 Liver cell carcinoma
0.778 0.222 0.000
I24 Other acute ischaemic heart diseases
0.778 0.222 0.000
Y57.9 Drug or medicament, unspecified
0.776 0.224 0.000
H43-H45 Disorders of vitreous body and globe
0.776 0.224 0.000
M21 Other acquired deformities of limbs
0.775 0.225 0.000
H33.2 Serous retinal detachment
0.775 0.225 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.774 0.226 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.774 0.226 0.000
K75 Other inflammatory liver diseases
0.774 0.226 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.773 0.227 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.772 0.228 0.000
T78 Adverse effects, not elsewhere classified
0.772 0.228 0.000
K08.3 Retained dental root
0.770 0.230 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.768 0.232 0.000
M05-M14 Inflammatory polyarthropathies
0.767 0.233 0.000
I72 Other aneurysm
0.767 0.233 0.000
D45 Polycythaemia vera
0.766 0.234 0.000
R10 Abdominal and pelvic pain
0.764 0.236 0.000
M80-M85 Disorders of bone density and structure
0.762 0.238 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.761 0.239 0.000
Y44 Agents primarily affecting blood constituents
0.760 0.240 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.759 0.241 0.000
M20.4 Other hammer toe(s) (acquired)
0.758 0.242 0.000
C18 Malignant neoplasm of colon
0.757 0.243 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.757 0.243 0.000
S90-S99 Injuries to the ankle and foot
0.757 0.243 0.000
Z46.6 Fitting and adjustment of urinary device
0.756 0.244 0.000
I74 Arterial embolism and thrombosis
0.755 0.245 0.000
H33.0 Retinal detachment with retinal break
0.755 0.245 0.000
C25 Malignant neoplasm of pancreas
0.754 0.246 0.000
S27 Injury of other and unspecified intrathoracic organs
0.754 0.246 0.000
K70 Alcoholic liver disease
0.754 0.246 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.753 0.247 0.000
M22.4 Chondromalacia patellae
0.753 0.247 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.749 0.250 0.000
K50-K52 Noninfective enteritis and colitis
0.749 0.251 0.000
Chapter VIII Diseases of the ear and mastoid process
0.746 0.254 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.745 0.255 0.000
K72 Hepatic failure, not elsewhere classified
0.745 0.255 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.745 0.255 0.000
C62 Malignant neoplasm of testis
0.743 0.257 0.000
Chapter VI Diseases of the nervous system
0.738 0.262 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.737 0.263 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.735 0.265 0.000
F99-F99 Unspecified mental disorder
0.732 0.267 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.732 0.268 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.731 0.269 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.731 0.269 0.000
S09 Other and unspecified injuries of head
0.730 0.270 0.000
J90 Pleural effusion, not elsewhere classified
0.727 0.273 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.273 0.000
Y52 Agents primarily affecting the cardiovascular system
0.726 0.274 0.000
I25.1 Atherosclerotic heart disease
0.725 0.275 0.000
Z45.2 Adjustment and management of vascular access device
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.724 0.276 0.000
M24 Other specific joint derangements
0.724 0.276 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.723 0.277 0.000
K62.0 Anal polyp
0.723 0.277 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.721 0.279 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.720 0.280 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.719 0.281 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
F10.9 Unspecified mental and behavioural disorder
0.717 0.283 0.000
F10.8 Other mental and behavioural disorders
0.717 0.283 0.000
F10.7 Residual and late-onset psychotic disorder
0.717 0.283 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
F10.5 Psychotic disorder
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.717 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.717 0.283 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.717 0.283 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
R10.3 Pain localised to other parts of lower abdomen
0.715 0.285 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.3 Aneurysm of heart
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.714 0.286 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.714 0.286 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.712 0.288 0.000
K92.8 Other specified diseases of digestive system
0.712 0.288 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.712 0.288 0.000
M67 Other disorders of synovium and tendon
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
F41.2 Mixed anxiety and depressive disorder
0.709 0.291 0.000
Z60 Problems related to social environment
0.708 0.292 0.000
H10-H13 Disorders of conjunctiva
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.294 0.000
D00-D09 In situ neoplasms
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.705 0.295 0.000
C60 Malignant neoplasm of penis
0.705 0.295 0.000
S29 Other and unspecified injuries of thorax
0.704 0.295 0.000
T79-T79 Certain early complications of trauma
0.704 0.296 0.000
I77.1 Stricture of artery
0.703 0.297 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.703 0.297 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.702 0.297 0.000
R47-R49 Symptoms and signs involving speech and voice
0.702 0.298 0.000
Z50.0 Cardiac rehabilitation
0.701 0.299 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.701 0.299 0.000
M91-M94 Chondropathies
0.700 0.300 0.000
M60-M63 Disorders of muscles
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
Y00-Y09 Assault
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X20-X29 Contact with venomous animals and plants
0.700 0.300 0.000
X10-X19 Contact with heat and hot substances
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V80-V89 Other land transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V40-V49 Car occupant injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
C51-C58 Malignant neoplasms of female genital organs
0.699 0.301 0.000
R17 Unspecified jaundice
0.699 0.301 0.000
C78.2 Secondary malignant neoplasm of pleura
0.699 0.301 0.000
Z41 Procedures for purposes other than remedying health state
0.698 0.302 0.000
S60-S69 Injuries to the wrist and hand
0.698 0.302 0.000
K62.6 Ulcer of anus and rectum
0.696 0.304 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.696 0.304 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.696 0.304 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.696 0.304 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.696 0.304 0.000
T82.1 Mechanical complication of cardiac electronic device
0.696 0.304 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.696 0.304 0.000
T42.4 Benzodiazepines
0.695 0.305 0.000
M20.3 Other deformity of hallux (acquired)
0.694 0.306 0.000
D48.1 Connective and other soft tissue
0.694 0.306 0.000
K14 Diseases of tongue
0.693 0.307 0.000
S52.6 Fracture of lower end of both ulna and radius
0.692 0.308 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.692 0.308 0.000
K59.0 Constipation
0.691 0.309 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.691 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.691 0.309 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
T36 Poisoning by systemic antibiotics
0.691 0.309 0.000
H55-H59 Other disorders of eye and adnexa
0.690 0.309 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.689 0.311 0.000
D60-D64 Aplastic and other anaemias
0.688 0.312 0.000
S09.9 Unspecified injury of head
0.686 0.314 0.000
S52.5 Fracture of lower end of radius
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
H25-H28 Disorders of lens
0.686 0.314 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.685 0.315 0.000
D46 Myelodysplastic syndromes
0.684 0.316 0.000
K35-K38 Diseases of appendix
0.684 0.316 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.684 0.316 0.000
K55 Vascular disorders of intestine
0.682 0.318 0.000
C15 Malignant neoplasm of oesophagus
0.682 0.318 0.000
C79 Secondary malignant neoplasm of other sites
0.681 0.319 0.000
K66 Other disorders of peritoneum
0.681 0.319 0.000
S40-S49 Injuries to the shoulder and upper arm
0.680 0.320 0.000
F45.8 Other somatoform disorders
0.680 0.320 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.680 0.320 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.680 0.320 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.680 0.320 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.680 0.320 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.680 0.320 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.680 0.320 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.680 0.320 0.000
K62.9 Disease of anus and rectum, unspecified
0.679 0.321 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
F40 Phobic anxiety disorders
0.679 0.321 0.000
Z49 Care involving dialysis
0.679 0.321 0.000
I20.9 Angina pectoris, unspecified
0.679 0.321 0.000
D48.5 Skin
0.678 0.322 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.678 0.322 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.678 0.322 0.000
M34 Systemic sclerosis
0.678 0.322 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
M32 Systemic lupus erythematosus
0.678 0.322 0.000
M30 Polyarteritis nodosa and related conditions
0.678 0.322 0.000
R15 Faecal incontinence
0.678 0.322 0.000
D48.0 Bone and articular cartilage
0.678 0.322 0.000
S80-S89 Injuries to the knee and lower leg
0.677 0.323 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.677 0.323 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.677 0.323 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.677 0.323 0.000
C22.1 Intrahepatic bile duct carcinoma
0.676 0.324 0.000
H34 Retinal vascular occlusions
0.675 0.325 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.674 0.326 0.000
R04 Haemorrhage from respiratory passages
0.674 0.326 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.674 0.326 0.000
M35 Other systemic involvement of connective tissue
0.674 0.326 0.000
Z63 Other problems related to primary support group, including family circumstances
0.674 0.326 0.000
Z51.8 Other specified medical care
0.673 0.327 0.000
K60 Fissure and fistula of anal and rectal regions
0.672 0.328 0.000
F41.9 Anxiety disorder, unspecified
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.670 0.330 0.000
M54 Dorsalgia
0.670 0.330 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.670 0.330 0.000
F43 Reaction to severe stress, and adjustment disorders
0.670 0.330 0.000
C50 Malignant neoplasm of breast
0.670 0.330 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.669 0.331 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.669 0.331 0.000
C21 Malignant neoplasm of anus and anal canal
0.669 0.331 0.000
C17 Malignant neoplasm of small intestine
0.669 0.331 0.000
C23 Malignant neoplasm of gallbladder
0.669 0.331 0.000
K59.8 Other specified functional intestinal disorders
0.669 0.331 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.668 0.332 0.000
Z04 Examination and observation for other reasons
0.668 0.332 0.000
H36 Retinal disorders in diseases classified elsewhere
0.668 0.332 0.000
I22 Subsequent myocardial infarction
0.667 0.332 0.000
C44 Other malignant neoplasms of skin
0.667 0.333 0.000
Z54 Convalescence
0.666 0.334 0.000
Z52 Donors of organs and tissues
0.666 0.334 0.000
Z44 Fitting and adjustment of external prosthetic device
0.666 0.334 0.000
J00-J06 Acute upper respiratory infections
0.666 0.334 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.666 0.334 0.000
K58 Irritable bowel syndrome
0.665 0.335 0.000
F48 Other neurotic disorders
0.665 0.335 0.000
F44 Dissociative [conversion] disorders
0.665 0.335 0.000
F42 Obsessive-compulsive disorder
0.665 0.335 0.000
Z13 Special screening examination for other diseases and disorders
0.665 0.335 0.000
M20.1 Hallux valgus (acquired)
0.663 0.337 0.000
M70-M79 Other soft tissue disorders
0.663 0.337 0.000
K51 Ulcerative colitis
0.662 0.338 0.000
Z51.2 Other chemotherapy
0.661 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.339 0.000
Y58 Bacterial vaccines
0.661 0.339 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.339 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.339 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.339 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.339 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
S52.0 Fracture of upper end of ulna
0.660 0.340 0.000
S20 Superficial injury of thorax
0.659 0.341 0.000
K90.0 Coeliac disease
0.659 0.341 0.000
I72.4 Aneurysm of artery of lower extremity
0.658 0.342 0.000
S51 Open wound of forearm
0.658 0.342 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
K65 Peritonitis
0.657 0.343 0.000
H33.5 Other retinal detachments
0.657 0.343 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.656 0.343 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.656 0.343 0.000
T85.2 Mechanical complication of intraocular lens
0.656 0.343 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.656 0.343 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.656 0.343 0.000
C91 Lymphoid leukaemia
0.656 0.344 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.655 0.345 0.000
J09-J18 Influenza and pneumonia
0.655 0.345 0.000
H43 Disorders of vitreous body
0.654 0.346 0.000
M21.3 Wrist or foot drop (acquired)
0.653 0.347 0.000
Y40 Systemic antibiotics
0.653 0.347 0.000
J93 Pneumothorax
0.652 0.348 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.652 0.348 0.000
K59.9 Functional intestinal disorder, unspecified
0.652 0.348 0.000
R21 Rash and other nonspecific skin eruption
0.652 0.348 0.000
M15-M19 Arthrosis
0.651 0.348 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.651 0.349 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.650 0.350 0.000
K11 Diseases of salivary glands
0.650 0.350 0.000
Z42 Follow-up care involving plastic surgery
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.350 0.000
K75.4 Autoimmune hepatitis
0.648 0.352 0.000
Z43.3 Attention to colostomy
0.647 0.353 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.646 0.353 0.000
H31 Other disorders of choroid
0.646 0.353 0.000
H30 Chorioretinal inflammation
0.646 0.353 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.646 0.354 0.000
S59 Other and unspecified injuries of forearm
0.646 0.354 0.000
S58 Traumatic amputation of forearm
0.646 0.354 0.000
S57 Crushing injury of forearm
0.646 0.354 0.000
S56 Injury of muscle and tendon at forearm level
0.646 0.354 0.000
S55 Injury of blood vessels at forearm level
0.646 0.354 0.000
S54 Injury of nerves at forearm level
0.646 0.354 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.646 0.354 0.000
S50 Superficial injury of forearm
0.646 0.354 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.646 0.354 0.000
S26 Injury of heart
0.646 0.354 0.000
S25 Injury of blood vessels of thorax
0.646 0.354 0.000
S24 Injury of nerves and spinal cord at thorax level
0.646 0.354 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.646 0.354 0.000
S21 Open wound of thorax
0.646 0.354 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.646 0.354 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.646 0.354 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.646 0.354 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.646 0.354 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.646 0.354 0.000
Y44.2 Anticoagulants
0.645 0.355 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.645 0.355 0.000
Z48 Other surgical follow-up care
0.645 0.355 0.000
S70 Superficial injury of hip and thigh
0.645 0.355 0.000
D37.0 Lip, oral cavity and pharynx
0.644 0.356 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.644 0.356 0.000
V10-V19 Pedal cyclist injured in transport accident
0.644 0.356 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.643 0.357 0.000
K77 Liver disorders in diseases classified elsewhere
0.643 0.357 0.000
K73 Chronic hepatitis, not elsewhere classified
0.643 0.357 0.000
K71 Toxic liver disease
0.643 0.357 0.000
Z13.9 Special screening examination, unspecified
0.643 0.357 0.000
C78.0 Secondary malignant neoplasm of lung
0.642 0.358 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.642 0.358 0.000
C50.8 Overlapping lesion of breast
0.642 0.358 0.000
C80 Malignant neoplasm without specification of site
0.641 0.359 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.641 0.359 0.000
Z51.9 Medical care, unspecified
0.641 0.359 0.000
Z51.6 Desensitisation to allergens
0.641 0.359 0.000
S27.2 Traumatic heamopneumothorax
0.641 0.359 0.000
M25 Other joint disorders, not elsewhere classified
0.641 0.359 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.640 0.360 0.000
Z50.1 Other physical therapy
0.640 0.360 0.000
C92 Myeloid leukaemia
0.640 0.360 0.000
C18.9 Colon, unspecified
0.640 0.360 0.000
Z43.1 Attention to gastrostomy
0.639 0.361 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.639 0.361 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.639 0.361 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.639 0.361 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.639 0.361 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.639 0.361 0.000
T45.0 Antiallergic and antiemetic drugs
0.638 0.362 0.000
I74.5 Embolism and thrombosis of iliac artery
0.638 0.362 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.638 0.362 0.000
C25.9 Pancreas, unspecified
0.637 0.363 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.637 0.363 0.000
K72.9 Hepatic failure, unspecified
0.637 0.363 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.636 0.364 0.000
M22.8 Other disorders of patella
0.634 0.366 0.000
R19.6 Halitosis
0.634 0.366 0.000
R19.3 Abdominal rigidity
0.634 0.366 0.000
R19.2 Visible peristalsis
0.634 0.366 0.000
R19.1 Abnormal bowel sounds
0.634 0.366 0.000
M40-M43 Deforming dorsopathies
0.634 0.366 0.000
C81 Hodgkin's disease
0.634 0.366 0.000
K61 Abscess of anal and rectal regions
0.633 0.367 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.632 0.368 0.000
H33.4 Traction detachment of retina
0.632 0.368 0.000
H33.1 Retinoschisis and retinal cysts
0.632 0.368 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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