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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77388539
log Bayes Factor = 22.0252
Chromosome 4   position 167,556,784  (GRCh37) Explore rs77388539 on Ensembl!
Variant rs77388539 is part of Cluster X0213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.984 0.016 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.982 0.018 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.982 0.018 0.000
I20-I25 Ischaemic heart diseases
0.981 0.019 0.000
R10 Abdominal and pelvic pain
0.980 0.020 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.977 0.023 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.973 0.027 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
J40-J47 Chronic lower respiratory diseases
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
Chapter VI Diseases of the nervous system
0.966 0.034 0.000
J44 Other chronic obstructive pulmonary disease
0.962 0.038 0.000
I25 Chronic ischaemic heart disease
0.961 0.039 0.000
I34 Nonrheumatic mitral valve disorders
0.958 0.042 0.000
T81 Complications of procedures, not elsewhere classified
0.958 0.042 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.954 0.046 0.000
R10.4 Other and unspecified abdominal pain
0.953 0.047 0.000
S40-S49 Injuries to the shoulder and upper arm
0.952 0.048 0.000
D60-D64 Aplastic and other anaemias
0.936 0.064 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.933 0.067 0.000
R13 Dysphagia
0.932 0.068 0.000
J30-J39 Other diseases of upper respiratory tract
0.928 0.072 0.000
G90-G99 Other disorders of the nervous system
0.928 0.072 0.000
M70-M79 Other soft tissue disorders
0.926 0.074 0.000
R04 Haemorrhage from respiratory passages
0.924 0.076 0.000
I67 Other cerebrovascular diseases
0.923 0.077 0.000
R30-R39 Symptoms and signs involving the urinary system
0.922 0.078 0.000
E86 Volume depletion
0.921 0.079 0.000
R94 Abnormal results of function studies
0.921 0.079 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.919 0.081 0.000
Chapter XIV Diseases of the genitourinary system
0.914 0.086 0.000
E83 Disorders of mineral metabolism
0.913 0.087 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.912 0.088 0.000
I34.0 Mitral (valve) insufficiency
0.911 0.089 0.000
Chapter I Certain infectious and parasitic diseases
0.908 0.092 0.000
Chapter II Neoplasms
0.906 0.094 0.000
R04.2 Haemoptysis
0.906 0.094 0.000
I25.1 Atherosclerotic heart disease
0.904 0.096 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.904 0.096 0.000
F10.1 Harmful use
0.903 0.097 0.000
D50-D53 Nutritional anaemias
0.902 0.098 0.000
R10.3 Pain localised to other parts of lower abdomen
0.901 0.099 0.000
M50 Cervical disk disorders
0.901 0.099 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.901 0.099 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.898 0.102 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.897 0.103 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.895 0.105 0.000
R00 Abnormalities of heart beat
0.894 0.106 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.892 0.108 0.000
I49 Other cardiac arrhythmias
0.892 0.108 0.000
S42 Fracture of shoulder and upper arm
0.891 0.109 0.000
R15 Faecal incontinence
0.890 0.110 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.890 0.110 0.000
I45 Other conduction disorders
0.889 0.111 0.000
R94.5 Abnormal results of liver function studies
0.887 0.113 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.887 0.113 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.884 0.116 0.000
I44 Atrioventricular and left bundle-branch block
0.883 0.117 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.878 0.122 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.876 0.124 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.872 0.127 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.871 0.129 0.000
I42 Cardiomyopathy
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.871 0.129 0.000
R31 Unspecified haematuria
0.866 0.134 0.000
F10.0 Acute intoxication
0.866 0.134 0.000
D64 Other anaemias
0.864 0.136 0.000
I38 Endocarditis, valve unspecified
0.864 0.136 0.000
F10.3 Withdrawal state
0.863 0.137 0.000
J20-J22 Other acute lower respiratory infections
0.862 0.138 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.861 0.139 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.858 0.142 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.858 0.142 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.856 0.144 0.000
I20 Angina pectoris
0.856 0.144 0.000
J30 Vasomotor and allergic rhinitis
0.855 0.145 0.000
M79.6 Pain in limb
0.855 0.145 0.000
M54 Dorsalgia
0.854 0.146 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.853 0.147 0.000
F10.2 Dependence syndrome
0.853 0.147 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
F41 Other anxiety disorders
0.849 0.151 0.000
G95 Other diseases of spinal cord
0.848 0.152 0.000
I67.8 Other specified cerebrovascular diseases
0.846 0.154 0.000
E83.5 Disorders of calcium metabolism
0.843 0.157 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.842 0.158 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.838 0.162 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.837 0.163 0.000
I65.2 Occlusion and stenosis of carotid artery
0.837 0.163 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.834 0.166 0.000
N17-N19 Renal failure
0.833 0.167 0.000
D50 Iron deficiency anaemia
0.832 0.168 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.831 0.169 0.000
I51 Complications and ill-defined descriptions of heart disease
0.830 0.170 0.000
N30-N39 Other diseases of urinary system
0.829 0.171 0.000
I67.9 Cerebrovascular disease, unspecified
0.829 0.171 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.828 0.172 0.000
R07 Pain in throat and chest
0.827 0.173 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.824 0.176 0.000
I20.9 Angina pectoris, unspecified
0.819 0.181 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.819 0.181 0.000
G40-G47 Episodic and paroxysmal disorders
0.819 0.181 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.816 0.184 0.000
V10-V19 Pedal cyclist injured in transport accident
0.815 0.185 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.815 0.185 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.813 0.187 0.000
J39 Other diseases of upper respiratory tract
0.813 0.187 0.000
D64.9 Anaemia, unspecified
0.813 0.187 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.812 0.188 0.000
I71 Aortic aneurysm and dissection
0.812 0.188 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.810 0.190 0.000
S50-S59 Injuries to the elbow and forearm
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.191 0.000
M50.2 Other cervical disk displacement
0.808 0.192 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.807 0.193 0.000
I45.1 Other and unspecified right bundle-branch block
0.807 0.193 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.807 0.193 0.000
B95-B98 Bacterial, viral and other infectious agents
0.806 0.194 0.000
R07.2 Precordial pain
0.805 0.195 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.804 0.196 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.802 0.198 0.000
M54.9 Dorsalgia, unspecified
0.802 0.198 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.801 0.199 0.000
I30 Acute pericarditis
0.799 0.201 0.000
S00-S09 Injuries to the head
0.799 0.201 0.000
M50.0 Cervical disk disorder with myelopathy
0.797 0.203 0.000
S42.2 Fracture of upper end of humerus
0.797 0.203 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.796 0.204 0.000
F60-F69 Disorders of adult personality and behaviour
0.795 0.205 0.000
J30.1 Allergic rhinitis due to pollen
0.794 0.206 0.000
R16.1 Splenomegaly, not elsewhere classified
0.793 0.207 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.792 0.208 0.000
F30-F39 Mood [affective] disorders
0.791 0.209 0.000
D50.9 Iron deficiency anaemia, unspecified
0.790 0.210 0.000
M65-M68 Disorders of synovium and tendon
0.789 0.211 0.000
I34.1 Mitral (valve) prolapse
0.789 0.211 0.000
G47 Sleep disorders
0.787 0.213 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.786 0.214 0.000
I49.9 Cardiac arrhythmia, unspecified
0.786 0.214 0.000
N00-N08 Glomerular diseases
0.785 0.215 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.784 0.216 0.000
E65-E68 Obesity and other hyperalimentation
0.784 0.216 0.000
N18 Chronic renal failure
0.783 0.217 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.782 0.218 0.000
S90-S99 Injuries to the ankle and foot
0.782 0.218 0.000
W20-W49 Exposure to inanimate mechanical forces
0.782 0.218 0.000
M79.66 Pain in limb (Lower leg)
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.780 0.220 0.000
C15-C26 Malignant neoplasms of digestive organs
0.779 0.221 0.000
S80-S89 Injuries to the knee and lower leg
0.778 0.222 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.778 0.222 0.000
R10.0 Acute abdomen
0.777 0.222 0.000
I44.7 Left bundle-branch block, unspecified
0.774 0.226 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.773 0.226 0.000
I22 Subsequent myocardial infarction
0.773 0.227 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.773 0.227 0.000
S60-S69 Injuries to the wrist and hand
0.772 0.228 0.000
S42.0 Fracture of clavicle
0.772 0.228 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.770 0.230 0.000
S20-S29 Injuries to the thorax
0.770 0.230 0.000
M51 Other intervertebral disk disorders
0.770 0.230 0.000
X50-X57 Overexertion, travel and privation
0.770 0.230 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.769 0.231 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.769 0.231 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.768 0.232 0.000
N20-N23 Urolithiasis
0.765 0.235 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.765 0.235 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.764 0.236 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.764 0.236 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.764 0.236 0.000
E10-E14 Diabetes mellitus
0.764 0.236 0.000
M45-M49 Spondylopathies
0.763 0.237 0.000
Chapter VIII Diseases of the ear and mastoid process
0.762 0.238 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.762 0.238 0.000
Y44 Agents primarily affecting blood constituents
0.761 0.239 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.761 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.761 0.239 0.000
Y83.8 Other surgical procedures
0.760 0.240 0.000
E50-E64 Other nutritional deficiencies
0.758 0.241 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.757 0.243 0.000
E83.1 Disorders of iron metabolism
0.757 0.243 0.000
R33 Retention of urine
0.757 0.243 0.000
F41.9 Anxiety disorder, unspecified
0.756 0.244 0.000
L03 Cellulitis
0.755 0.245 0.000
G47.3 Sleep apnoea
0.755 0.245 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.755 0.245 0.000
I31 Other diseases of pericardium
0.755 0.245 0.000
Chapter XXII Codes for special purposes
0.754 0.246 0.000
G93 Other disorders of brain
0.754 0.246 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.754 0.246 0.000
T81.9 Unspecified complication of procedure
0.750 0.250 0.000
R10.2 Pelvic and perineal pain
0.748 0.252 0.000
F17.1 Harmful use
0.748 0.252 0.000
V20-V29 Motorcycle rider injured in transport accident
0.747 0.253 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.745 0.255 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.744 0.256 0.000
R35 Polyuria
0.744 0.256 0.000
R12 Heartburn
0.744 0.256 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
J20 Acute bronchitis
0.743 0.257 0.000
M20-M25 Other joint disorders
0.742 0.258 0.000
I26 Pulmonary embolism
0.740 0.260 0.000
A30-A49 Other bacterial diseases
0.739 0.261 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.738 0.262 0.000
R94.4 Abnormal results of kidney function studies
0.738 0.262 0.000
G95.2 Cord compression, unspecified
0.737 0.263 0.000
R00.1 Bradycardia, unspecified
0.736 0.264 0.000
L08 Other local infections of skin and subcutaneous tissue
0.735 0.265 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.734 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.734 0.266 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.733 0.267 0.000
Y95 Nosocomial condition
0.733 0.267 0.000
N18.9 Chronic renal failure, unspecified
0.733 0.267 0.000
J60-J70 Lung diseases due to external agents
0.733 0.267 0.000
T82.1 Mechanical complication of cardiac electronic device
0.732 0.268 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.732 0.268 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.732 0.268 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.732 0.268 0.000
J39.2 Other diseases of pharynx
0.731 0.269 0.000
Y52 Agents primarily affecting the cardiovascular system
0.731 0.269 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.730 0.270 0.000
S42.20 Fracture of upper end of humerus (closed)
0.729 0.270 0.000
C60-C63 Malignant neoplasms of male genital organs
0.729 0.271 0.000
N36 Other disorders of urethra
0.728 0.272 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.726 0.274 0.000
I60 Subarachnoid haemorrhage
0.726 0.274 0.000
I42.9 Cardiomyopathy, unspecified
0.725 0.275 0.000
M53 Other dorsopathies, not elsewhere classified
0.725 0.275 0.000
J40 Bronchitis, not specified as acute or chronic
0.724 0.275 0.000
I44.0 Atrioventricular block, first degree
0.724 0.276 0.000
D68 Other coagulation defects
0.724 0.276 0.000
G95.9 Disease of spinal cord, unspecified
0.723 0.277 0.000
J35 Chronic diseases of tonsils and adenoids
0.722 0.278 0.000
J00-J06 Acute upper respiratory infections
0.721 0.279 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.719 0.281 0.000
N35 Urethral stricture
0.718 0.282 0.000
Chapter XXI Factors influencing health status and contact with health services
0.718 0.282 0.000
I49.8 Other specified cardiac arrhythmias
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
E20-E35 Disorders of other endocrine glands
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
I62 Other nontraumatic intracranial haemorrhage
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.711 0.289 0.000
D80-D89 Certain disorders involving the immune mechanism
0.711 0.289 0.000
C34 Malignant neoplasm of bronchus and lung
0.711 0.289 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.710 0.290 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.710 0.290 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.710 0.290 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.710 0.290 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.710 0.290 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.710 0.290 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.710 0.290 0.000
F11 Mental and behavioural disorders due to use of opioids
0.710 0.290 0.000
I69 Sequelae of cerebrovascular disease
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.709 0.291 0.000
J43 Emphysema
0.709 0.291 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.708 0.292 0.000
T87 Complications peculiar to reattachment and amputation
0.708 0.292 0.000
T86 Failure and rejection of transplanted organs and tissues
0.708 0.292 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.707 0.293 0.000
M84 Disorders of continuity of bone
0.707 0.293 0.000
R17 Unspecified jaundice
0.706 0.294 0.000
M79.2 Neuralgia and neuritis, unspecified
0.706 0.294 0.000
I51.9 Heart disease, unspecified
0.706 0.294 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.705 0.295 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.705 0.295 0.000
L10-L14 Bullous disorders
0.704 0.296 0.000
J38.5 Laryngeal spasm
0.704 0.296 0.000
R11 Nausea and vomiting
0.704 0.296 0.000
F10.9 Unspecified mental and behavioural disorder
0.704 0.296 0.000
F10.8 Other mental and behavioural disorders
0.704 0.296 0.000
F10.7 Residual and late-onset psychotic disorder
0.704 0.296 0.000
F10.6 Amnesic syndrome
0.704 0.296 0.000
F10.5 Psychotic disorder
0.704 0.296 0.000
F10.4 Withdrawal state with delirium
0.704 0.296 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.704 0.296 0.000
I23 Certain current complications following acute myocardial infarction
0.703 0.297 0.000
Y57 Other and unspecified drugs and medicaments
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
C32 Malignant neoplasm of larynx
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.702 0.298 0.000
F40 Phobic anxiety disorders
0.702 0.298 0.000
L90 Atrophic disorders of skin
0.701 0.299 0.000
J95-J99 Other diseases of the respiratory system
0.701 0.299 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.700 0.300 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.699 0.300 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
L60-L75 Disorders of skin appendages
0.698 0.302 0.000
L84 Corns and callosities
0.698 0.302 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.697 0.303 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.697 0.303 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.697 0.303 0.000
J38.4 Oedema of larynx
0.697 0.303 0.000
E88 Other metabolic disorders
0.697 0.303 0.000
E85 Amyloidosis
0.697 0.303 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
J41 Simple and mucopurulent chronic bronchitis
0.696 0.304 0.000
J46 Status asthmaticus
0.696 0.304 0.000
J42 Unspecified chronic bronchitis
0.696 0.304 0.000
S51 Open wound of forearm
0.696 0.304 0.000
M54.1 Radiculopathy
0.695 0.305 0.000
S43.0 Dislocation of shoulder joint
0.693 0.307 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.693 0.307 0.000
J47 Bronchiectasis
0.692 0.308 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.692 0.308 0.000
I25.5 Ischaemic cardiomyopathy
0.692 0.308 0.000
Y86 Sequelae of other accidents
0.691 0.309 0.000
J84 Other interstitial pulmonary diseases
0.690 0.309 0.000
I47 Paroxysmal tachycardia
0.690 0.310 0.000
D61 Other aplastic anaemias
0.690 0.310 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.310 0.000
M81 Osteoporosis without pathological fracture
0.689 0.311 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.689 0.311 0.000
M80 Osteoporosis with pathological fracture
0.689 0.311 0.000
I25.6 Silent myocardial ischaemia
0.689 0.311 0.000
I25.4 Coronary artery aneurysm
0.689 0.311 0.000
I25.3 Aneurysm of heart
0.689 0.311 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.689 0.311 0.000
M40-M43 Deforming dorsopathies
0.687 0.313 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.687 0.313 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.687 0.313 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.687 0.313 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.687 0.313 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.687 0.313 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.687 0.313 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.686 0.314 0.000
S42.00 Fracture of clavicle (closed)
0.686 0.314 0.000
R00.0 Tachycardia, unspecified
0.686 0.314 0.000
I42.0 Dilated cardiomyopathy
0.685 0.315 0.000
J38.2 Nodules of vocal cords
0.685 0.315 0.000
M79.1 Myalgia
0.685 0.315 0.000
B35-B49 Mycoses
0.684 0.316 0.000
C25 Malignant neoplasm of pancreas
0.684 0.316 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.684 0.316 0.000
L04 Acute lymphadenitis
0.684 0.316 0.000
L01 Impetigo
0.684 0.316 0.000
L00 Staphylococcal scalded skin syndrome
0.684 0.316 0.000
M77 Other enthesopathies
0.683 0.316 0.000
L57.0 Actinic keratosis
0.683 0.317 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.683 0.317 0.000
J38.7 Other diseases of larynx
0.683 0.317 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.682 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.682 0.317 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.682 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.682 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.682 0.317 0.000
S41 Open wound of shoulder and upper arm
0.682 0.317 0.000
S40 Superficial injury of shoulder and upper arm
0.682 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.682 0.317 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
L05 Pilonidal cyst
0.680 0.320 0.000
M89 Other disorders of bone
0.680 0.320 0.000
S72 Fracture of femur
0.679 0.320 0.000
H10-H13 Disorders of conjunctiva
0.679 0.321 0.000
D73 Diseases of spleen
0.679 0.321 0.000
H40-H42 Glaucoma
0.678 0.322 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.677 0.322 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.676 0.324 0.000
R06 Abnormalities of breathing
0.676 0.324 0.000
R00.2 Palpitations
0.676 0.324 0.000
L89 Decubitus ulcer
0.676 0.324 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
L20-L30 Dermatitis and eczema
0.675 0.325 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.675 0.325 0.000
D51 Vitamin B12 deficiency anaemia
0.674 0.326 0.000
C18 Malignant neoplasm of colon
0.674 0.326 0.000
I44.2 Atrioventricular block, complete
0.673 0.327 0.000
M79.67 Pain in limb (Ankle and foot)
0.672 0.328 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.671 0.329 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.671 0.329 0.000
D62 Acute posthaemorrhagic anaemia
0.671 0.329 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.671 0.329 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.671 0.329 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.670 0.330 0.000
G30-G32 Other degenerative diseases of the nervous system
0.670 0.330 0.000
I05-I09 Chronic rheumatic heart diseases
0.670 0.330 0.000
J22 Unspecified acute lower respiratory infection
0.668 0.332 0.000
R01 Cardiac murmurs and other cardiac sounds
0.668 0.332 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.667 0.333 0.000
M67 Other disorders of synovium and tendon
0.666 0.334 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.666 0.334 0.000
J37 Chronic laryngitis and laryngotracheitis
0.665 0.334 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.665 0.335 0.000
G96 Other disorders of central nervous system
0.665 0.335 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.665 0.335 0.000
G90 Disorders of autonomic nervous system
0.665 0.335 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.665 0.335 0.000
G92 Toxic encephalopathy
0.665 0.335 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.664 0.336 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.664 0.336 0.000
R39 Other symptoms and signs involving the urinary system
0.664 0.336 0.000
L91 Hypertrophic disorders of skin
0.664 0.336 0.000
H25-H28 Disorders of lens
0.664 0.336 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.336 0.000
M71 Other bursopathies
0.664 0.336 0.000
R18 Ascites
0.664 0.336 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.663 0.337 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.662 0.338 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.662 0.338 0.000
R04.1 Haemorrhage from throat
0.662 0.338 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.662 0.338 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.662 0.338 0.000
I67.5 Moyamoya disease
0.662 0.338 0.000
I67.4 Hypertensive encephalopathy
0.662 0.338 0.000
I67.3 Progressive vascular leukoencephalopathy
0.662 0.338 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.662 0.338 0.000
N23 Unspecified renal colic
0.661 0.339 0.000
R30 Pain associated with micturition
0.661 0.339 0.000
E83.4 Disorders of magnesium metabolism
0.661 0.339 0.000
R36 Urethral discharge
0.661 0.339 0.000
R34 Anuria and oliguria
0.661 0.339 0.000
F33 Recurrent depressive disorder
0.661 0.339 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.660 0.339 0.000
R94.7 Abnormal results of other endocrine function studies
0.660 0.339 0.000
R94.6 Abnormal results of thyroid function studies
0.660 0.339 0.000
R94.2 Abnormal results of pulmonary function studies
0.660 0.339 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.660 0.339 0.000
R94.0 Abnormal results of function studies of central nervous system
0.660 0.339 0.000
J33 Nasal polyp
0.660 0.340 0.000
M54.2 Cervicalgia
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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