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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77865213
log Bayes Factor = 21.1258
Chromosome 1   position 67,198,843  (GRCh37) Explore rs77865213 on Ensembl!
Variant rs77865213 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.993 0.007 0.000
K08 Other disorders of teeth and supporting structures
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
M70-M79 Other soft tissue disorders
0.991 0.009 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.987 0.013 0.000
Chapter II Neoplasms
0.987 0.013 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
K08.3 Retained dental root
0.979 0.021 0.000
M15-M19 Arthrosis
0.979 0.021 0.000
Chapter I Certain infectious and parasitic diseases
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
I60-I69 Cerebrovascular diseases
0.974 0.026 0.000
S60-S69 Injuries to the wrist and hand
0.969 0.031 0.000
M17 Gonarthrosis [arthrosis of knee]
0.968 0.032 0.000
M23 Internal derangement of knee
0.962 0.038 0.000
R00 Abnormalities of heart beat
0.961 0.039 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.960 0.040 0.000
I20-I25 Ischaemic heart diseases
0.958 0.042 0.000
R07 Pain in throat and chest
0.954 0.046 0.000
Chapter XX External causes of morbidity and mortality
0.952 0.048 0.000
I10-I15 Hypertensive diseases
0.947 0.053 0.000
M06 Other rheumatoid arthritis
0.944 0.056 0.000
A30-A49 Other bacterial diseases
0.938 0.062 0.000
J43 Emphysema
0.937 0.063 0.000
M65-M68 Disorders of synovium and tendon
0.929 0.071 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.929 0.071 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.926 0.074 0.000
M75 Shoulder lesions
0.923 0.077 0.000
K40-K46 Hernia
0.919 0.081 0.000
R00.2 Palpitations
0.919 0.081 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.918 0.082 0.000
R07.3 Other chest pain
0.918 0.082 0.000
C15-C26 Malignant neoplasms of digestive organs
0.917 0.083 0.000
M17.1 Other primary gonarthrosis
0.917 0.083 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.916 0.084 0.000
I71 Aortic aneurysm and dissection
0.915 0.085 0.000
Chapter VIII Diseases of the ear and mastoid process
0.915 0.085 0.000
M72 Fibroblastic disorders
0.913 0.087 0.000
M06.9 Rheumatoid arthritis, unspecified
0.908 0.092 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.907 0.093 0.000
K50-K52 Noninfective enteritis and colitis
0.904 0.096 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.904 0.096 0.000
M25 Other joint disorders, not elsewhere classified
0.902 0.098 0.000
I67 Other cerebrovascular diseases
0.896 0.104 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.896 0.104 0.000
Chapter VII Diseases of the eye and adnexa
0.894 0.106 0.000
J43.9 Emphysema, unspecified
0.894 0.106 0.000
A41 Other septicaemia
0.892 0.108 0.000
M23.8 Other internal derangements of knee
0.888 0.112 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.887 0.113 0.000
M17.9 Gonarthrosis, unspecified
0.886 0.114 0.000
S61 Open wound of wrist and hand
0.884 0.116 0.000
M80-M85 Disorders of bone density and structure
0.883 0.117 0.000
Chapter VI Diseases of the nervous system
0.880 0.120 0.000
I10 Essential (primary) hypertension
0.880 0.120 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.880 0.120 0.000
M40-M43 Deforming dorsopathies
0.879 0.121 0.000
K13 Other diseases of lip and oral mucosa
0.879 0.121 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.878 0.122 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.877 0.123 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.875 0.125 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.871 0.129 0.000
A00-A09 Intestinal infectious diseases
0.870 0.130 0.000
M13 Other arthritis
0.870 0.130 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.869 0.131 0.000
I21 Acute myocardial infarction
0.868 0.132 0.000
R30-R39 Symptoms and signs involving the urinary system
0.867 0.133 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.859 0.141 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.858 0.142 0.000
J00-J06 Acute upper respiratory infections
0.858 0.142 0.000
K05 Gingivitis and periodontal diseases
0.857 0.143 0.000
M65 Synovitis and tenosynovitis
0.856 0.144 0.000
M19 Other arthrosis
0.855 0.145 0.000
R07.4 Chest pain, unspecified
0.855 0.145 0.000
M75.4 Impingement syndrome of shoulder
0.854 0.146 0.000
K50 Crohn's disease [regional enteritis]
0.854 0.146 0.000
M45-M49 Spondylopathies
0.852 0.148 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.851 0.149 0.000
R00.1 Bradycardia, unspecified
0.848 0.152 0.000
J46 Status asthmaticus
0.847 0.153 0.000
K70-K77 Diseases of liver
0.844 0.156 0.000
T66-T78 Other and unspecified effects of external causes
0.839 0.161 0.000
J09-J18 Influenza and pneumonia
0.839 0.161 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.837 0.163 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.836 0.164 0.000
G90-G99 Other disorders of the nervous system
0.835 0.165 0.000
K35-K38 Diseases of appendix
0.835 0.165 0.000
C78.7 Secondary malignant neoplasm of liver
0.833 0.167 0.000
D00-D09 In situ neoplasms
0.833 0.167 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.831 0.169 0.000
J42 Unspecified chronic bronchitis
0.830 0.170 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.830 0.170 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.829 0.171 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.827 0.173 0.000
M25.7 Osteophyte
0.823 0.177 0.000
I25 Chronic ischaemic heart disease
0.821 0.179 0.000
R02 Gangrene, not elsewhere classified
0.820 0.180 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.819 0.181 0.000
M17.0 Primary gonarthrosis, bilateral
0.819 0.181 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.818 0.182 0.000
M75.1 Rotator cuff syndrome
0.816 0.184 0.000
I24 Other acute ischaemic heart diseases
0.815 0.185 0.000
I21.9 Acute myocardial infarction, unspecified
0.814 0.186 0.000
H40-H42 Glaucoma
0.813 0.187 0.000
C18 Malignant neoplasm of colon
0.813 0.187 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.813 0.187 0.000
K00 Disorders of tooth development and eruption
0.812 0.188 0.000
D10-D36 Benign neoplasms
0.812 0.188 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.811 0.189 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.810 0.190 0.000
K65-K67 Diseases of peritoneum
0.810 0.190 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.809 0.191 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.808 0.192 0.000
I69 Sequelae of cerebrovascular disease
0.808 0.192 0.000
S50-S59 Injuries to the elbow and forearm
0.806 0.194 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.805 0.195 0.000
H90-H95 Other disorders of ear
0.804 0.196 0.000
R31 Unspecified haematuria
0.804 0.196 0.000
I67.8 Other specified cerebrovascular diseases
0.804 0.196 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.803 0.197 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.800 0.200 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.800 0.200 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
M86-M90 Other osteopathies
0.799 0.201 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.798 0.201 0.000
M24 Other specific joint derangements
0.798 0.202 0.000
I30-I52 Other forms of heart disease
0.797 0.203 0.000
R26 Abnormalities of gait and mobility
0.796 0.203 0.000
K42 Umbilical hernia
0.796 0.204 0.000
I12 Hypertensive renal disease
0.796 0.204 0.000
J02 Acute pharyngitis
0.795 0.205 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.793 0.207 0.000
S62 Fracture at wrist and hand level
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.792 0.208 0.000
I67.9 Cerebrovascular disease, unspecified
0.791 0.209 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.791 0.209 0.000
M13.9 Arthritis, unspecified
0.789 0.211 0.000
K14 Diseases of tongue
0.787 0.213 0.000
I73 Other peripheral vascular diseases
0.785 0.215 0.000
S00-S09 Injuries to the head
0.784 0.216 0.000
M07 Psoriatic and enteropathic arthropathies
0.784 0.216 0.000
I72 Other aneurysm
0.784 0.216 0.000
G93 Other disorders of brain
0.783 0.217 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.783 0.217 0.000
I77 Other disorders of arteries and arterioles
0.781 0.219 0.000
R04 Haemorrhage from respiratory passages
0.781 0.219 0.000
S61.8 Open wound of other parts of wrist and hand
0.779 0.221 0.000
M23.4 Loose body in knee
0.778 0.222 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.778 0.222 0.000
T18 Foreign body in alimentary tract
0.777 0.223 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.777 0.223 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.777 0.223 0.000
C20 Malignant neoplasm of rectum
0.776 0.224 0.000
M22 Disorders of patella
0.775 0.225 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.774 0.226 0.000
M05 Seropositive rheumatoid arthritis
0.772 0.228 0.000
M34 Systemic sclerosis
0.772 0.228 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.772 0.228 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.771 0.229 0.000
M81 Osteoporosis without pathological fracture
0.771 0.229 0.000
H65-H75 Diseases of middle ear and mastoid
0.769 0.231 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.767 0.233 0.000
A40 Streptococcal septicaemia
0.766 0.234 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
K01 Embedded and impacted teeth
0.765 0.235 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.759 0.241 0.000
M75.2 Bicipital tendinitis
0.758 0.242 0.000
K50.9 Crohn's disease, unspecified
0.758 0.242 0.000
Y40 Systemic antibiotics
0.758 0.242 0.000
J20-J22 Other acute lower respiratory infections
0.757 0.243 0.000
K43 Ventral hernia
0.756 0.244 0.000
H40 Glaucoma
0.756 0.244 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.755 0.245 0.000
K05.3 Chronic periodontitis
0.754 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.754 0.246 0.000
T79-T79 Certain early complications of trauma
0.754 0.246 0.000
F30-F39 Mood [affective] disorders
0.753 0.247 0.000
G30-G32 Other degenerative diseases of the nervous system
0.753 0.247 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.752 0.247 0.000
R10 Abdominal and pelvic pain
0.752 0.248 0.000
B15-B19 Viral hepatitis
0.752 0.248 0.000
K13.0 Diseases of lips
0.752 0.248 0.000
J02.9 Acute pharyngitis, unspecified
0.751 0.249 0.000
R06 Abnormalities of breathing
0.751 0.249 0.000
I78 Diseases of capillaries
0.749 0.251 0.000
T93 Sequelae of injuries of lower limb
0.749 0.251 0.000
C79 Secondary malignant neoplasm of other sites
0.748 0.252 0.000
M19.0 Primary arthrosis of other joints
0.747 0.253 0.000
Y83.3 Surgical operation with formation of external stoma
0.746 0.254 0.000
M67 Other disorders of synovium and tendon
0.746 0.254 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.746 0.254 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.746 0.254 0.000
Chapter XIV Diseases of the genitourinary system
0.745 0.255 0.000
M25.77 Osteophyte (Ankle and foot)
0.745 0.255 0.000
I62 Other nontraumatic intracranial haemorrhage
0.745 0.255 0.000
Y83.6 Removal of other organ (partial) (total)
0.745 0.255 0.000
M48 Other spondylopathies
0.745 0.255 0.000
H60-H62 Diseases of external ear
0.744 0.256 0.000
C80 Malignant neoplasm without specification of site
0.744 0.256 0.000
K12 Stomatitis and related lesions
0.744 0.256 0.000
M43 Other deforming dorsopathies
0.744 0.256 0.000
R13 Dysphagia
0.744 0.256 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.257 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.742 0.258 0.000
M77 Other enthesopathies
0.741 0.259 0.000
I42 Cardiomyopathy
0.741 0.259 0.000
J90-J94 Other diseases of pleura
0.740 0.260 0.000
D27 Benign neoplasm of ovary
0.740 0.260 0.000
G93.3 Postviral fatigue syndrome
0.740 0.260 0.000
I74 Arterial embolism and thrombosis
0.740 0.260 0.000
I70 Atherosclerosis
0.739 0.261 0.000
K07 Dentofacial anomalies [including malocclusion]
0.737 0.263 0.000
I71.0 Dissection of aorta [any part]
0.737 0.263 0.000
H10-H13 Disorders of conjunctiva
0.737 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
F11 Mental and behavioural disorders due to use of opioids
0.737 0.263 0.000
C91 Lymphoid leukaemia
0.737 0.263 0.000
M06.0 Seronegative rheumatoid arthritis
0.736 0.264 0.000
K51 Ulcerative colitis
0.736 0.264 0.000
K50.1 Crohn's disease of large intestine
0.735 0.265 0.000
B25-B34 Other viral diseases
0.734 0.266 0.000
M79.8 Other specified soft tissue disorders
0.731 0.269 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.730 0.270 0.000
I25.1 Atherosclerotic heart disease
0.729 0.271 0.000
H91 Other hearing loss
0.728 0.272 0.000
K44 Diaphragmatic hernia
0.727 0.273 0.000
S61.1 Open wound of finger(s) with damage to nail
0.726 0.274 0.000
M65.3 Trigger finger
0.726 0.274 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.725 0.274 0.000
T78 Adverse effects, not elsewhere classified
0.725 0.275 0.000
Y57 Other and unspecified drugs and medicaments
0.724 0.276 0.000
K04 Diseases of pulp and periapical tissues
0.723 0.277 0.000
I20 Angina pectoris
0.723 0.277 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.722 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.720 0.280 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.280 0.000
M41 Scoliosis
0.720 0.280 0.000
S69 Other and unspecified injuries of wrist and hand
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I63 Cerebral infarction
0.716 0.284 0.000
K10 Other diseases of jaws
0.716 0.284 0.000
K09 Cysts of oral region, not elsewhere classified
0.716 0.284 0.000
K03 Other diseases of hard tissues of teeth
0.716 0.284 0.000
S20-S29 Injuries to the thorax
0.716 0.284 0.000
K40 Inguinal hernia
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
S10-S19 Injuries to the neck
0.715 0.284 0.000
D24 Benign neoplasm of breast
0.714 0.286 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.714 0.286 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.713 0.287 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.713 0.287 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.711 0.289 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.711 0.289 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.711 0.289 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.711 0.289 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.710 0.290 0.000
M71 Other bursopathies
0.710 0.290 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.710 0.290 0.000
Y43 Primarily systemic agents
0.709 0.291 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.708 0.292 0.000
S60 Superficial injury of wrist and hand
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.707 0.293 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.707 0.293 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
M21 Other acquired deformities of limbs
0.707 0.293 0.000
F40 Phobic anxiety disorders
0.706 0.294 0.000
Y83.4 Other reconstructive surgery
0.706 0.294 0.000
C25 Malignant neoplasm of pancreas
0.706 0.294 0.000
M14 Arthropathies in other diseases classified elsewhere
0.705 0.295 0.000
M12 Other specific arthropathies
0.705 0.295 0.000
M11 Other crystal arthropathies
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
J60-J70 Lung diseases due to external agents
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.702 0.297 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.702 0.298 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.702 0.298 0.000
M15 Polyarthrosis
0.702 0.298 0.000
R07.1 Chest pain on breathing
0.702 0.298 0.000
F17.1 Harmful use
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.700 0.300 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.700 0.300 0.000
C92 Myeloid leukaemia
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
F80-F89 Disorders of psychological development
0.699 0.301 0.000
F70-F79 Mental retardation
0.699 0.301 0.000
F60-F69 Disorders of adult personality and behaviour
0.699 0.301 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.301 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.301 0.000
F41 Other anxiety disorders
0.699 0.301 0.000
H40.9 Glaucoma, unspecified
0.699 0.301 0.000
J47 Bronchiectasis
0.698 0.302 0.000
M80 Osteoporosis with pathological fracture
0.697 0.302 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.696 0.304 0.000
K02 Dental caries
0.695 0.305 0.000
K35 Acute appendicitis
0.695 0.305 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.305 0.000
S67 Crushing injury of wrist and hand
0.694 0.305 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.305 0.000
A49 Bacterial infection of unspecified site
0.694 0.306 0.000
M17.5 Other secondary gonarthrosis
0.694 0.306 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.694 0.306 0.000
M17.3 Other posttraumatic gonarthrosis
0.694 0.306 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.694 0.306 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.694 0.306 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.693 0.307 0.000
R29.6 Tendency to fall, not elsewhere classified
0.693 0.307 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.692 0.308 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.691 0.309 0.000
R06.0 Dyspnoea
0.691 0.309 0.000
I73.0 Raynaud's syndrome
0.691 0.309 0.000
M25.8 Other specified joint disorders
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.690 0.310 0.000
S90-S99 Injuries to the ankle and foot
0.690 0.310 0.000
M23.9 Internal derangement of knee, unspecified
0.690 0.310 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.690 0.310 0.000
M23.5 Chronic instability of knee
0.690 0.310 0.000
M23.1 Discoid meniscus (congenital)
0.690 0.310 0.000
M23.0 Cystic meniscus
0.690 0.310 0.000
M81.9 Osteoporosis, unspecified
0.690 0.310 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.689 0.311 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.689 0.311 0.000
F10.1 Harmful use
0.688 0.312 0.000
N40-N51 Diseases of male genital organs
0.687 0.313 0.000
I38 Endocarditis, valve unspecified
0.687 0.313 0.000
I42.0 Dilated cardiomyopathy
0.687 0.313 0.000
S51 Open wound of forearm
0.687 0.313 0.000
I23 Certain current complications following acute myocardial infarction
0.687 0.313 0.000
M25.5 Pain in joint
0.685 0.315 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.685 0.315 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.683 0.317 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
Y00-Y09 Assault
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X60-X84 Intentional self-harm
0.683 0.317 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
W50-W64 Exposure to animate mechanical forces
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.682 0.318 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.682 0.318 0.000
K75 Other inflammatory liver diseases
0.682 0.318 0.000
S64 Injury of nerves at wrist and hand level
0.680 0.320 0.000
K70 Alcoholic liver disease
0.680 0.320 0.000
I15 Secondary hypertension
0.679 0.321 0.000
I13 Hypertensive heart and renal disease
0.679 0.321 0.000
I11 Hypertensive heart disease
0.679 0.321 0.000
K00.6 Disturbances in tooth eruption
0.679 0.321 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.677 0.323 0.000
T59 Toxic effect of other gases, fumes and vapours
0.677 0.323 0.000
I12.0 Hypertensive renal disease with renal failure
0.677 0.323 0.000
M06.8 Other specified rheumatoid arthritis
0.677 0.323 0.000
M06.4 Inflammatory polyarthropathy
0.677 0.323 0.000
M06.3 Rheumatoid nodule
0.677 0.323 0.000
M06.2 Rheumatoid bursitis
0.677 0.323 0.000
M06.1 Adult-onset Still's disease
0.677 0.323 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.677 0.323 0.000
S06 Intracranial injury
0.677 0.323 0.000
T31 Burns classified according to extent of body surface involved
0.677 0.323 0.000
F10.3 Withdrawal state
0.676 0.324 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
H30-H36 Disorders of choroid and retina
0.674 0.326 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.673 0.327 0.000
H91.9 Hearing loss, unspecified
0.673 0.327 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.673 0.327 0.000
A48 Other bacterial diseases, not elsewhere classified
0.673 0.327 0.000
A44 Bartonellosis
0.673 0.327 0.000
A43 Nocardiosis
0.673 0.327 0.000
A42 Actinomycosis
0.673 0.327 0.000
A39 Meningococcal infection
0.673 0.327 0.000
A37 Whooping cough
0.673 0.327 0.000
A36 Diphtheria
0.673 0.327 0.000
A32 Listeriosis
0.673 0.327 0.000
A31 Infection due to other mycobacteria
0.673 0.327 0.000
A30 Leprosy [Hansen's disease]
0.673 0.327 0.000
A46 Erysipelas
0.673 0.327 0.000
A38 Scarlet fever
0.673 0.327 0.000
A35 Other tetanus
0.673 0.327 0.000
A34 Obstetrical tetanus
0.673 0.327 0.000
A33 Tetanus neonatorum
0.673 0.327 0.000
K11 Diseases of salivary glands
0.673 0.327 0.000
R07.0 Pain in throat
0.672 0.328 0.000
J43.8 Other emphysema
0.672 0.328 0.000
J43.2 Centrilobular emphysema
0.672 0.328 0.000
J43.1 Panlobular emphysema
0.672 0.328 0.000
J43.0 MacLeod's syndrome
0.672 0.328 0.000
K66 Other disorders of peritoneum
0.672 0.328 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.671 0.329 0.000
D06 Carcinoma in situ of cervix uteri
0.670 0.330 0.000
G20-G26 Extrapyramidal and movement disorders
0.670 0.330 0.000
T92 Sequelae of injuries of upper limb
0.670 0.330 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.670 0.330 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.669 0.331 0.000
R04.2 Haemoptysis
0.668 0.331 0.000
J95-J99 Other diseases of the respiratory system
0.668 0.332 0.000
C85.1 B-cell lymphoma, unspecified
0.668 0.332 0.000
M48.0 Spinal stenosis
0.668 0.332 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.668 0.332 0.000
R30 Pain associated with micturition
0.667 0.333 0.000
I83 Varicose veins of lower extremities
0.667 0.333 0.000
K50.0 Crohn's disease of small intestine
0.666 0.334 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.666 0.334 0.000
M66 Spontaneous rupture of synovium and tendon
0.666 0.334 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.666 0.334 0.000
C18.7 Sigmoid colon
0.665 0.335 0.000
I27 Other pulmonary heart diseases
0.665 0.335 0.000
R27 Other lack of coordination
0.665 0.335 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.664 0.336 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.664 0.336 0.000
R17 Unspecified jaundice
0.664 0.336 0.000
R18 Ascites
0.664 0.336 0.000
T18.1 Foreign body in oesophagus
0.664 0.336 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
C95 Leukaemia of unspecified cell type
0.664 0.336 0.000
C94 Other leukaemias of specified cell type
0.664 0.336 0.000
C93 Monocytic leukaemia
0.664 0.336 0.000
C88 Malignant immunoproliferative diseases
0.664 0.336 0.000
C86 Other specified types of T/NK-cell lymphoma
0.664 0.336 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.664 0.336 0.000
C81 Hodgkin's disease
0.664 0.336 0.000
M24.1 Other articular cartilage disorders
0.663 0.337 0.000
C18.4 Transverse colon
0.663 0.337 0.000
S62.3 Fracture of other metacarpal bone
0.663 0.337 0.000
T81 Complications of procedures, not elsewhere classified
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
M75.8 Other shoulder lesions
0.662 0.338 0.000
M75.9 Shoulder lesion, unspecified
0.662 0.338 0.000
M46 Other inflammatory spondylopathies
0.661 0.339 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.661 0.339 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.660 0.340 0.000
K45 Other abdominal hernia
0.659 0.341 0.000
R33 Retention of urine
0.659 0.341 0.000
S40-S49 Injuries to the shoulder and upper arm
0.658 0.342 0.000
T63 Toxic effect of contact with venomous animals
0.658 0.342 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.657 0.343 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.657 0.343 0.000
C21 Malignant neoplasm of anus and anal canal
0.657 0.343 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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