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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78049208
log Bayes Factor = 21.4107
Chromosome 1   position 218,613,620  (GRCh37) Explore rs78049208 on Ensembl!
Variant rs78049208 is part of Cluster X0156

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
K40-K46 Hernia
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
N81 Female genital prolapse
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
K40 Inguinal hernia
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
T81 Complications of procedures, not elsewhere classified
0.989 0.011 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
S60-S69 Injuries to the wrist and hand
0.980 0.020 0.000
N81.6 Rectocele
0.979 0.021 0.000
K44 Diaphragmatic hernia
0.978 0.022 0.000
K55-K64 Other diseases of intestines
0.978 0.022 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
I20-I25 Ischaemic heart diseases
0.973 0.027 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
F32 Depressive episode
0.966 0.034 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.963 0.037 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.963 0.037 0.000
N84 Polyp of female genital tract
0.959 0.041 0.000
N95 Menopausal and other perimenopausal disorders
0.957 0.043 0.000
F32.9 Depressive episode, unspecified
0.957 0.043 0.000
S61 Open wound of wrist and hand
0.957 0.043 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.957 0.043 0.000
R50-R69 General symptoms and signs
0.954 0.046 0.000
N40-N51 Diseases of male genital organs
0.952 0.048 0.000
Chapter VII Diseases of the eye and adnexa
0.949 0.051 0.000
M70-M79 Other soft tissue disorders
0.947 0.053 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.946 0.054 0.000
I60-I69 Cerebrovascular diseases
0.943 0.057 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.941 0.059 0.000
N89 Other noninflammatory disorders of vagina
0.940 0.060 0.000
I34 Nonrheumatic mitral valve disorders
0.940 0.060 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.939 0.061 0.000
Chapter II Neoplasms
0.937 0.063 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.936 0.064 0.000
K70-K77 Diseases of liver
0.933 0.067 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.931 0.069 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.930 0.070 0.000
D10-D36 Benign neoplasms
0.929 0.071 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.927 0.073 0.000
I49 Other cardiac arrhythmias
0.922 0.078 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.921 0.079 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.919 0.081 0.000
R60 Oedema, not elsewhere classified
0.918 0.082 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.917 0.083 0.000
I69 Sequelae of cerebrovascular disease
0.917 0.083 0.000
D12.2 Ascending colon
0.916 0.084 0.000
G40-G47 Episodic and paroxysmal disorders
0.915 0.085 0.000
N84.0 Polyp of corpus uteri
0.914 0.086 0.000
Chapter I Certain infectious and parasitic diseases
0.914 0.086 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.911 0.089 0.000
H02 Other disorders of eyelid
0.905 0.095 0.000
N95.0 Postmenopausal bleeding
0.904 0.096 0.000
N81.3 Complete uterovaginal prolapse
0.899 0.101 0.000
K90-K93 Other diseases of the digestive system
0.896 0.104 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.893 0.107 0.000
S80-S89 Injuries to the knee and lower leg
0.892 0.108 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.891 0.109 0.000
S61.8 Open wound of other parts of wrist and hand
0.889 0.111 0.000
Chapter VIII Diseases of the ear and mastoid process
0.888 0.112 0.000
H04 Disorders of lachrymal system
0.886 0.114 0.000
I25 Chronic ischaemic heart disease
0.885 0.115 0.000
N10-N16 Renal tubulo-interstitial diseases
0.885 0.115 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.883 0.117 0.000
I34.0 Mitral (valve) insufficiency
0.883 0.117 0.000
T39.1 4-Aminophenol derivatives
0.883 0.117 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.880 0.120 0.000
F33 Recurrent depressive disorder
0.879 0.121 0.000
N81.2 Incomplete uterovaginal prolapse
0.876 0.124 0.000
K43 Ventral hernia
0.875 0.125 0.000
D12.3 Transverse colon
0.874 0.126 0.000
D12.0 Caecum
0.873 0.127 0.000
R60.0 Localised oedema
0.873 0.127 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.873 0.127 0.000
R00 Abnormalities of heart beat
0.871 0.129 0.000
I21 Acute myocardial infarction
0.866 0.134 0.000
K92 Other diseases of digestive system
0.864 0.136 0.000
N81.4 Uterovaginal prolapse, unspecified
0.863 0.137 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.862 0.138 0.000
K60 Fissure and fistula of anal and rectal regions
0.859 0.140 0.000
N80 Endometriosis
0.858 0.142 0.000
M75 Shoulder lesions
0.856 0.144 0.000
K62 Other diseases of anus and rectum
0.853 0.147 0.000
N50 Other disorders of male genital organs
0.853 0.147 0.000
S61.7 Multiple open wounds of wrist and hand
0.849 0.151 0.000
R00.1 Bradycardia, unspecified
0.847 0.153 0.000
R55 Syncope and collapse
0.846 0.154 0.000
K56.2 Volvulus
0.845 0.155 0.000
B95-B98 Bacterial, viral and other infectious agents
0.840 0.160 0.000
K56.6 Other and unspecified intestinal obstruction
0.839 0.161 0.000
S20-S29 Injuries to the thorax
0.838 0.162 0.000
R63 Symptoms and signs concerning food and fluid intake
0.832 0.168 0.000
K14 Diseases of tongue
0.831 0.169 0.000
W20-W49 Exposure to inanimate mechanical forces
0.830 0.170 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.829 0.171 0.000
M79.0 Rheumatism, unspecified
0.827 0.173 0.000
I34.1 Mitral (valve) prolapse
0.823 0.177 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.822 0.178 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.821 0.179 0.000
H02.3 Blepharochalasis
0.820 0.180 0.000
I63 Cerebral infarction
0.820 0.180 0.000
R07 Pain in throat and chest
0.820 0.180 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.819 0.181 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.817 0.183 0.000
A30-A49 Other bacterial diseases
0.814 0.186 0.000
K70 Alcoholic liver disease
0.814 0.186 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
W00-W19 Falls
0.812 0.188 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.810 0.190 0.000
N40 Hyperplasia of prostate
0.809 0.191 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.809 0.191 0.000
S50-S59 Injuries to the elbow and forearm
0.808 0.192 0.000
G40 Epilepsy
0.802 0.198 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.802 0.198 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.801 0.199 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.798 0.202 0.000
K75 Other inflammatory liver diseases
0.797 0.203 0.000
N00-N08 Glomerular diseases
0.797 0.203 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.796 0.204 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.795 0.205 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.794 0.206 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.794 0.206 0.000
R53 Malaise and fatigue
0.793 0.207 0.000
K56.1 Intussusception
0.792 0.208 0.000
I44 Atrioventricular and left bundle-branch block
0.792 0.208 0.000
I25.1 Atherosclerotic heart disease
0.790 0.210 0.000
M86-M90 Other osteopathies
0.790 0.210 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.789 0.211 0.000
N99-N99 Other disorders of the genitourinary system
0.788 0.212 0.000
I69.3 Sequelae of cerebral infarction
0.786 0.214 0.000
T85.2 Mechanical complication of intraocular lens
0.784 0.216 0.000
R30-R39 Symptoms and signs involving the urinary system
0.783 0.217 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.783 0.217 0.000
M20-M25 Other joint disorders
0.783 0.217 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.783 0.217 0.000
K56.7 Ileus, unspecified
0.782 0.218 0.000
I49.8 Other specified cardiac arrhythmias
0.782 0.218 0.000
I22 Subsequent myocardial infarction
0.781 0.219 0.000
I42 Cardiomyopathy
0.781 0.219 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.781 0.219 0.000
R21 Rash and other nonspecific skin eruption
0.781 0.219 0.000
N42 Other disorders of prostate
0.781 0.219 0.000
O80-O84 Delivery
0.780 0.220 0.000
R07.0 Pain in throat
0.779 0.221 0.000
M79.8 Other specified soft tissue disorders
0.779 0.221 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.778 0.222 0.000
T86 Failure and rejection of transplanted organs and tissues
0.777 0.223 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.777 0.223 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.774 0.226 0.000
F41 Other anxiety disorders
0.774 0.226 0.000
N50.1 Vascular disorders of male genital organs
0.774 0.226 0.000
A49 Bacterial infection of unspecified site
0.774 0.226 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.773 0.227 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.773 0.227 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.772 0.228 0.000
G70-G73 Diseases of myoneural junction and muscle
0.771 0.229 0.000
M05-M14 Inflammatory polyarthropathies
0.771 0.229 0.000
K62.8 Other specified diseases of anus and rectum
0.770 0.230 0.000
I46 Cardiac arrest
0.770 0.230 0.000
N43 Hydrocele and spermatocele
0.770 0.230 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.769 0.231 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.769 0.231 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.769 0.231 0.000
N89.5 Stricture and atresia of vagina
0.769 0.231 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.768 0.231 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.768 0.232 0.000
G20-G26 Extrapyramidal and movement disorders
0.768 0.232 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
R23 Other skin changes
0.767 0.233 0.000
R60.9 Oedema, unspecified
0.766 0.234 0.000
D12.8 Rectum
0.766 0.234 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.766 0.234 0.000
K41 Femoral hernia
0.765 0.235 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
N13 Obstructive and reflux uropathy
0.763 0.237 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.762 0.238 0.000
K04 Diseases of pulp and periapical tissues
0.762 0.238 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.761 0.239 0.000
S69 Other and unspecified injuries of wrist and hand
0.759 0.241 0.000
I05-I09 Chronic rheumatic heart diseases
0.759 0.241 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.759 0.241 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.759 0.241 0.000
K63 Other diseases of intestine
0.758 0.242 0.000
H80-H83 Diseases of inner ear
0.757 0.243 0.000
N84.2 Polyp of vagina
0.756 0.244 0.000
K55 Vascular disorders of intestine
0.756 0.244 0.000
R52 Pain, not elsewhere classified
0.754 0.246 0.000
I49.0 Ventricular fibrillation and flutter
0.754 0.246 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.754 0.246 0.000
K76 Other diseases of liver
0.753 0.247 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.753 0.247 0.000
I45 Other conduction disorders
0.753 0.247 0.000
M75.5 Bursitis of shoulder
0.753 0.247 0.000
S61.1 Open wound of finger(s) with damage to nail
0.752 0.248 0.000
H60-H62 Diseases of external ear
0.751 0.249 0.000
K12 Stomatitis and related lesions
0.750 0.250 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.750 0.250 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.750 0.250 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.749 0.251 0.000
K92.1 Melaena
0.749 0.251 0.000
N81.8 Other female genital prolapse
0.749 0.251 0.000
N95.2 Postmenopausal atrophic vaginitis
0.745 0.255 0.000
H04.2 Epiphora
0.745 0.255 0.000
D12.6 Colon, unspecified
0.744 0.256 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.743 0.257 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.743 0.257 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.742 0.258 0.000
G90-G99 Other disorders of the nervous system
0.742 0.258 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.742 0.258 0.000
F99-F99 Unspecified mental disorder
0.741 0.259 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.741 0.259 0.000
D10 Benign neoplasm of mouth and pharynx
0.740 0.259 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.740 0.260 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.739 0.261 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.739 0.261 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.738 0.262 0.000
M75.4 Impingement syndrome of shoulder
0.738 0.262 0.000
I49.5 Sick sinus syndrome
0.738 0.262 0.000
S62 Fracture at wrist and hand level
0.737 0.263 0.000
I20 Angina pectoris
0.737 0.263 0.000
M79.7 Fibromyalgia
0.736 0.264 0.000
R35 Polyuria
0.736 0.264 0.000
O60-O75 Complications of labour and delivery
0.735 0.265 0.000
S64 Injury of nerves at wrist and hand level
0.735 0.265 0.000
I24 Other acute ischaemic heart diseases
0.735 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
S67 Crushing injury of wrist and hand
0.734 0.266 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.734 0.266 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.734 0.266 0.000
K01 Embedded and impacted teeth
0.734 0.266 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.733 0.267 0.000
K60.2 Anal fissure, unspecified
0.733 0.267 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.732 0.268 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.732 0.268 0.000
M25 Other joint disorders, not elsewhere classified
0.731 0.269 0.000
H02.1 Ectropion of eyelid
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.730 0.269 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.730 0.269 0.000
F33.9 Recurrent depressive disorder, unspecified
0.730 0.270 0.000
H43-H45 Disorders of vitreous body and globe
0.730 0.270 0.000
I49.9 Cardiac arrhythmia, unspecified
0.729 0.270 0.000
K60.1 Chronic anal fissure
0.729 0.270 0.000
S89 Other and unspecified injuries of lower leg
0.729 0.271 0.000
K14.9 Disease of tongue, unspecified
0.729 0.271 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.729 0.271 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
N84.1 Polyp of cervix uteri
0.726 0.273 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.726 0.274 0.000
C64-C68 Malignant neoplasms of urinary tract
0.725 0.275 0.000
R68 Other general symptoms and signs
0.725 0.275 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.725 0.275 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.725 0.275 0.000
H00 Hordeolum and chalazion
0.724 0.276 0.000
F60-F69 Disorders of adult personality and behaviour
0.724 0.276 0.000
M45-M49 Spondylopathies
0.723 0.277 0.000
K11 Diseases of salivary glands
0.723 0.277 0.000
K59 Other functional intestinal disorders
0.722 0.278 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.722 0.278 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.720 0.279 0.000
H02.6 Xanthelasma of eyelid
0.720 0.280 0.000
I33 Acute and subacute endocarditis
0.720 0.280 0.000
N81.1 Cystocele
0.719 0.281 0.000
S81 Open wound of lower leg
0.719 0.281 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.718 0.282 0.000
V10-V19 Pedal cyclist injured in transport accident
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
K46 Unspecified abdominal hernia
0.717 0.283 0.000
K45 Other abdominal hernia
0.717 0.283 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
N81.9 Female genital prolapse, unspecified
0.715 0.285 0.000
N81.0 Female urethrocele
0.715 0.285 0.000
H10-H13 Disorders of conjunctiva
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.715 0.285 0.000
I71 Aortic aneurysm and dissection
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
C51-C58 Malignant neoplasms of female genital organs
0.714 0.286 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.713 0.287 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
Y52 Agents primarily affecting the cardiovascular system
0.711 0.289 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.289 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.711 0.289 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.711 0.289 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.711 0.289 0.000
H02.5 Other disorders affecting eyelid function
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F80-F89 Disorders of psychological development
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
T81.9 Unspecified complication of procedure
0.709 0.291 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.709 0.291 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.709 0.291 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.709 0.291 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.709 0.291 0.000
I31 Other diseases of pericardium
0.709 0.291 0.000
N48 Other disorders of penis
0.709 0.291 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.708 0.292 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.708 0.292 0.000
K35-K38 Diseases of appendix
0.708 0.292 0.000
K07 Dentofacial anomalies [including malocclusion]
0.707 0.293 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.707 0.293 0.000
N17-N19 Renal failure
0.707 0.293 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.706 0.294 0.000
S86 Injury of muscle and tendon at lower leg level
0.705 0.295 0.000
K65-K67 Diseases of peritoneum
0.705 0.295 0.000
R94 Abnormal results of function studies
0.705 0.295 0.000
I21.4 Acute subendocardial myocardial infarction
0.704 0.296 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.704 0.296 0.000
Y35-Y36 Legal intervention and operations of war
0.704 0.296 0.000
Y10-Y34 Event of undetermined intent
0.704 0.296 0.000
Y00-Y09 Assault
0.704 0.296 0.000
X85-X99 Assault
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.704 0.296 0.000
X50-X57 Overexertion, travel and privation
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.704 0.296 0.000
X30-X39 Exposure to forces of nature
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.704 0.296 0.000
X10-X19 Contact with heat and hot substances
0.704 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.704 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.704 0.296 0.000
W75-W84 Other accidental threats to breathing
0.704 0.296 0.000
W65-W74 Accidental drowning and submersion
0.704 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.296 0.000
V98-V99 Other and unspecified transport accidents
0.704 0.296 0.000
V95-V97 Air and space transport accidents
0.704 0.296 0.000
V90-V94 Water transport accidents
0.704 0.296 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.704 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.704 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.704 0.296 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.704 0.296 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.703 0.297 0.000
D23 Other benign neoplasms of skin
0.703 0.297 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F30 Manic episode
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.297 0.000
S60 Superficial injury of wrist and hand
0.703 0.297 0.000
N80.3 Endometriosis of pelvic peritoneum
0.702 0.298 0.000
K44.1 Diaphragmatic hernia with gangrene
0.701 0.299 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.701 0.299 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.701 0.299 0.000
K50-K52 Noninfective enteritis and colitis
0.701 0.299 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.701 0.299 0.000
I49.4 Other and unspecified premature depolarisation
0.701 0.299 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.701 0.299 0.000
S80 Superficial injury of lower leg
0.700 0.300 0.000
B35-B49 Mycoses
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
I30 Acute pericarditis
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
N30-N39 Other diseases of urinary system
0.698 0.302 0.000
I23 Certain current complications following acute myocardial infarction
0.698 0.302 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.697 0.302 0.000
R59 Enlarged lymph nodes
0.697 0.303 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
O80 Single spontaneous delivery
0.696 0.304 0.000
K61 Abscess of anal and rectal regions
0.696 0.304 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.696 0.304 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.304 0.000
F42 Obsessive-compulsive disorder
0.695 0.304 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.694 0.306 0.000
I21.9 Acute myocardial infarction, unspecified
0.693 0.307 0.000
A49.0 Staphylococcal infection, unspecified
0.693 0.307 0.000
F32.8 Other depressive episodes
0.693 0.307 0.000
F32.0 Mild depressive episode
0.693 0.307 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.691 0.309 0.000
H01 Other inflammation of eyelid
0.691 0.309 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.690 0.310 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.690 0.310 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.690 0.310 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.690 0.310 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.690 0.310 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.690 0.310 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
T36 Poisoning by systemic antibiotics
0.690 0.310 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.690 0.310 0.000
D34 Benign neoplasm of thyroid gland
0.690 0.310 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.690 0.310 0.000
D60-D64 Aplastic and other anaemias
0.690 0.310 0.000
R63.4 Abnormal weight loss
0.689 0.311 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.688 0.312 0.000
N84.9 Polyp of female genital tract, unspecified
0.688 0.312 0.000
N84.8 Polyp of other parts of female genital tract
0.688 0.312 0.000
N84.3 Polyp of vulva
0.688 0.312 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.688 0.312 0.000
N80.9 Endometriosis, unspecified
0.687 0.313 0.000
N80.1 Endometriosis of ovary
0.687 0.313 0.000
D12.7 Rectosigmoid junction
0.686 0.313 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.686 0.314 0.000
N95.3 States associated with artificial menopause
0.686 0.314 0.000
N95.1 Menopausal and female climacteric states
0.686 0.314 0.000
S61.0 Open wound of finger(s) without damage to nail
0.686 0.314 0.000
K56.3 Gallstone ileus
0.686 0.314 0.000
K56.0 Paralytic ileus
0.686 0.314 0.000
S00-S09 Injuries to the head
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.685 0.314 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.685 0.315 0.000
M75.1 Rotator cuff syndrome
0.685 0.315 0.000
D37.5 Rectum
0.685 0.315 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.684 0.316 0.000
R62 Lack of expected normal physiological development
0.684 0.316 0.000
R57 Shock, not elsewhere classified
0.684 0.316 0.000
R64 Cachexia
0.684 0.316 0.000
R58 Haemorrhage, not elsewhere classified
0.684 0.316 0.000
I38 Endocarditis, valve unspecified
0.683 0.317 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.682 0.317 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.682 0.317 0.000
N46 Male infertility
0.682 0.317 0.000
N44 Torsion of testis
0.682 0.317 0.000
G45.3 Amaurosis fugax
0.682 0.318 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.682 0.318 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.682 0.318 0.000
R50 Fever of unknown origin
0.682 0.318 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.681 0.319 0.000
H04.1 Other disorders of lachrymal gland
0.681 0.319 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.681 0.319 0.000
H02.4 Ptosis of eyelid
0.681 0.319 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
M76 Enthesopathies of lower limb, excluding foot
0.679 0.321 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.679 0.321 0.000
M71 Other bursopathies
0.679 0.321 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.678 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y44 Agents primarily affecting blood constituents
0.678 0.322 0.000
C15-C26 Malignant neoplasms of digestive organs
0.678 0.322 0.000
H02.0 Entropion and trichiasis of eyelid
0.678 0.322 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.678 0.322 0.000
K92.0 Haematemesis
0.678 0.322 0.000
N10 Acute tubulo-interstitial nephritis
0.677 0.323 0.000
I44.0 Atrioventricular block, first degree
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.676 0.324 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.676 0.324 0.000
D27 Benign neoplasm of ovary
0.676 0.324 0.000
K08 Other disorders of teeth and supporting structures
0.675 0.325 0.000
I49.3 Ventricular premature depolarisation
0.675 0.325 0.000
R01 Cardiac murmurs and other cardiac sounds
0.675 0.325 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.675 0.325 0.000
H05 Disorders of orbit
0.675 0.325 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.675 0.325 0.000
K05 Gingivitis and periodontal diseases
0.674 0.325 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.674 0.326 0.000
K04.5 Chronic apical periodontitis
0.674 0.326 0.000
N97 Female infertility
0.674 0.326 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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