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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78775229
log Bayes Factor = 15.1154
Chromosome 18   position 36,175,363  (GRCh37) Explore rs78775229 on Ensembl!
Variant rs78775229 is part of Cluster X0091

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.999 0.001 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.990 0.010 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
F41 Other anxiety disorders
0.982 0.018 0.000
C78.0 Secondary malignant neoplasm of lung
0.975 0.025 0.000
S01 Open wound of head
0.970 0.030 0.000
Chapter VIII Diseases of the ear and mastoid process
0.967 0.033 0.000
S00 Superficial injury of head
0.963 0.037 0.000
M80-M85 Disorders of bone density and structure
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.962 0.038 0.000
C64-C68 Malignant neoplasms of urinary tract
0.962 0.038 0.000
F41.9 Anxiety disorder, unspecified
0.956 0.044 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.953 0.047 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.953 0.047 0.000
F41.2 Mixed anxiety and depressive disorder
0.950 0.050 0.000
F30-F39 Mood [affective] disorders
0.948 0.052 0.000
Chapter XX External causes of morbidity and mortality
0.944 0.056 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.941 0.059 0.000
M45-M49 Spondylopathies
0.939 0.061 0.000
M75 Shoulder lesions
0.933 0.067 0.000
C67 Malignant neoplasm of bladder
0.923 0.077 0.000
J95-J99 Other diseases of the respiratory system
0.923 0.077 0.000
S01.8 Open wound of other parts of head
0.920 0.080 0.000
M50-M54 Other dorsopathies
0.916 0.084 0.000
F32 Depressive episode
0.914 0.086 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.914 0.086 0.000
M81 Osteoporosis without pathological fracture
0.913 0.087 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.911 0.089 0.000
S02 Fracture of skull and facial bones
0.908 0.092 0.000
Chapter VI Diseases of the nervous system
0.907 0.093 0.000
J09-J18 Influenza and pneumonia
0.906 0.094 0.000
H65-H75 Diseases of middle ear and mastoid
0.904 0.096 0.000
S00.8 Superficial injury of other parts of head
0.902 0.098 0.000
M86-M90 Other osteopathies
0.901 0.099 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.899 0.101 0.000
J98 Other respiratory disorders
0.898 0.102 0.000
C67.9 Bladder, unspecified
0.898 0.102 0.000
T39.1 4-Aminophenol derivatives
0.898 0.102 0.000
F32.9 Depressive episode, unspecified
0.897 0.103 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.897 0.103 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.896 0.104 0.000
S60-S69 Injuries to the wrist and hand
0.891 0.109 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.879 0.121 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.878 0.122 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.869 0.131 0.000
M54 Dorsalgia
0.869 0.131 0.000
O36 Maternal care for other known or suspected foetal problems
0.866 0.134 0.000
M81.9 Osteoporosis, unspecified
0.865 0.135 0.000
J98.4 Other disorders of lung
0.863 0.137 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.852 0.148 0.000
J18 Pneumonia, organism unspecified
0.851 0.149 0.000
S20-S29 Injuries to the thorax
0.851 0.149 0.000
M54.9 Dorsalgia, unspecified
0.850 0.150 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.849 0.151 0.000
S01.7 Multiple open wounds of head
0.848 0.152 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.847 0.153 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.845 0.155 0.000
S06 Intracranial injury
0.844 0.156 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.834 0.166 0.000
M47 Spondylosis
0.833 0.167 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.832 0.168 0.000
O80-O84 Delivery
0.830 0.170 0.000
M75.4 Impingement syndrome of shoulder
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.828 0.172 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.827 0.173 0.000
O00-O08 Pregnancy with abortive outcome
0.825 0.175 0.000
C77.5 Intrapelvic lymph nodes
0.825 0.175 0.000
S01.0 Open wound of scalp
0.824 0.176 0.000
M79.6 Pain in limb
0.824 0.176 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.824 0.176 0.000
J18.1 Lobar pneumonia, unspecified
0.823 0.177 0.000
M45 Ankylosing spondylitis
0.821 0.179 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.818 0.182 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.818 0.182 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.814 0.186 0.000
C78.2 Secondary malignant neoplasm of pleura
0.813 0.187 0.000
M65-M68 Disorders of synovium and tendon
0.812 0.188 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.810 0.190 0.000
O20 Haemorrhage in early pregnancy
0.810 0.190 0.000
M90 Osteopathies in diseases classified elsewhere
0.809 0.191 0.000
O26.8 Other specified pregnancy-related conditions
0.807 0.193 0.000
J20-J22 Other acute lower respiratory infections
0.805 0.195 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.803 0.197 0.000
H60-H62 Diseases of external ear
0.803 0.197 0.000
C78.7 Secondary malignant neoplasm of liver
0.802 0.198 0.000
M91-M94 Chondropathies
0.801 0.199 0.000
C77.1 Intrathoracic lymph nodes
0.800 0.200 0.000
S02.1 Fracture of base of skull
0.799 0.201 0.000
H90-H95 Other disorders of ear
0.796 0.204 0.000
S00.1 Contusion of eyelid and periocular area
0.795 0.205 0.000
Chapter XIV Diseases of the genitourinary system
0.794 0.206 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.793 0.207 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.792 0.208 0.000
S00.7 Multiple superficial injuries of head
0.791 0.209 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.781 0.219 0.000
M47.8 Other spondylosis
0.780 0.220 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.779 0.221 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.777 0.223 0.000
T43.2 Other and unspecified antidepressants
0.776 0.224 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
N10-N16 Renal tubulo-interstitial diseases
0.775 0.225 0.000
F45 Somatoform disorders
0.773 0.227 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.772 0.228 0.000
H73 Other disorders of tympanic membrane
0.771 0.229 0.000
M80 Osteoporosis with pathological fracture
0.770 0.230 0.000
S68 Traumatic amputation of wrist and hand
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.769 0.231 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.767 0.233 0.000
O36.8 Maternal care for other specified foetal problems
0.767 0.233 0.000
N20-N23 Urolithiasis
0.766 0.234 0.000
O32.2 Maternal care for transverse and oblique lie
0.766 0.234 0.000
C79.2 Secondary malignant neoplasm of skin
0.764 0.236 0.000
D00-D09 In situ neoplasms
0.763 0.237 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.763 0.237 0.000
C43 Malignant melanoma of skin
0.762 0.238 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.762 0.238 0.000
W00-W19 Falls
0.761 0.239 0.000
T66-T78 Other and unspecified effects of external causes
0.759 0.240 0.000
C80 Malignant neoplasm without specification of site
0.758 0.241 0.000
M71 Other bursopathies
0.757 0.243 0.000
O43 Placental disorders
0.757 0.243 0.000
J98.1 Pulmonary collapse
0.757 0.243 0.000
N13 Obstructive and reflux uropathy
0.755 0.245 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.247 0.000
N20 Calculus of kidney and ureter
0.753 0.247 0.000
H71 Cholesteatoma of middle ear
0.752 0.248 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.752 0.248 0.000
F40 Phobic anxiety disorders
0.751 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.749 0.251 0.000
M75.3 Calcific tendinitis of shoulder
0.748 0.252 0.000
C77.0 Lymph nodes of head, face and neck
0.748 0.252 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.747 0.253 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.747 0.253 0.000
M90.7 Fracture of bone in neoplastic disease
0.743 0.257 0.000
O36.9 Maternal care for foetal problem, unspecified
0.740 0.259 0.000
Y00-Y09 Assault
0.740 0.259 0.000
M85 Other disorders of bone density and structure
0.740 0.260 0.000
S80-S89 Injuries to the knee and lower leg
0.740 0.260 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.739 0.261 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.739 0.261 0.000
S01.4 Open wound of cheek and temporomandibular area
0.738 0.262 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.738 0.262 0.000
M79.69 Pain in limb (Site unspecified)
0.738 0.262 0.000
H72 Perforation of tympanic membrane
0.737 0.262 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.737 0.263 0.000
M72 Fibroblastic disorders
0.736 0.264 0.000
F20 Schizophrenia
0.734 0.266 0.000
M77 Other enthesopathies
0.734 0.266 0.000
O80 Single spontaneous delivery
0.733 0.267 0.000
F43 Reaction to severe stress, and adjustment disorders
0.731 0.269 0.000
M75.5 Bursitis of shoulder
0.731 0.269 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.731 0.269 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.730 0.270 0.000
S02.3 Fracture of orbital floor
0.728 0.272 0.000
M81.2 Osteoporosis of disuse
0.727 0.273 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.726 0.274 0.000
N13.3 Other and unspecified hydronephrosis
0.726 0.274 0.000
M75.0 Adhesive capsulitis of shoulder
0.726 0.274 0.000
M87 Osteonecrosis
0.725 0.274 0.000
O30 Multiple gestation
0.725 0.275 0.000
C43.5 Malignant melanoma of trunk
0.725 0.275 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.725 0.275 0.000
V40-V49 Car occupant injured in transport accident
0.725 0.275 0.000
V10-V19 Pedal cyclist injured in transport accident
0.723 0.277 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.723 0.277 0.000
T39.0 Salicylates
0.723 0.277 0.000
H74 Other disorders of middle ear and mastoid
0.722 0.278 0.000
M75.1 Rotator cuff syndrome
0.722 0.278 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.279 0.000
S02.10 Fracture of base of skull (closed)
0.720 0.280 0.000
F41.1 Generalised anxiety disorder
0.718 0.282 0.000
O02 Other abnormal products of conception
0.718 0.282 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
O23 Infections of genito-urinary tract in pregnancy
0.717 0.283 0.000
C79.6 Secondary malignant neoplasm of ovary
0.716 0.283 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.716 0.283 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.716 0.283 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.716 0.283 0.000
M79.2 Neuralgia and neuritis, unspecified
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.286 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.714 0.286 0.000
M48 Other spondylopathies
0.713 0.287 0.000
N20.1 Calculus of ureter
0.713 0.287 0.000
Q80-Q89 Other congenital malformations
0.713 0.287 0.000
M84 Disorders of continuity of bone
0.712 0.288 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.711 0.289 0.000
O48 Prolonged pregnancy
0.711 0.289 0.000
F48 Other neurotic disorders
0.710 0.290 0.000
F44 Dissociative [conversion] disorders
0.710 0.290 0.000
F42 Obsessive-compulsive disorder
0.710 0.290 0.000
C92 Myeloid leukaemia
0.710 0.290 0.000
S50-S59 Injuries to the elbow and forearm
0.709 0.291 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.707 0.293 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.707 0.293 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.707 0.293 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.707 0.293 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
S01.5 Open wound of lip and oral cavity
0.706 0.294 0.000
F41.8 Other specified anxiety disorders
0.704 0.296 0.000
F41.3 Other mixed anxiety disorders
0.704 0.296 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.704 0.296 0.000
F33 Recurrent depressive disorder
0.702 0.298 0.000
F80-F89 Disorders of psychological development
0.701 0.298 0.000
O40 Polyhydramnios
0.701 0.299 0.000
S02.2 Fracture of nasal bones
0.701 0.299 0.000
D60-D64 Aplastic and other anaemias
0.700 0.300 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.699 0.301 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.698 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.697 0.302 0.000
G57 Mononeuropathies of lower limb
0.697 0.303 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.697 0.303 0.000
S00.9 Superficial injury of head, part unspecified
0.694 0.306 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.694 0.306 0.000
S60 Superficial injury of wrist and hand
0.694 0.306 0.000
T40.2 Other opioids
0.694 0.306 0.000
J22 Unspecified acute lower respiratory infection
0.693 0.307 0.000
J98.9 Respiratory disorder, unspecified
0.691 0.309 0.000
J40-J47 Chronic lower respiratory diseases
0.691 0.309 0.000
S00.5 Superficial injury of lip and oral cavity
0.690 0.310 0.000
S00.4 Superficial injury of ear
0.690 0.310 0.000
S00.3 Superficial injury of nose
0.690 0.310 0.000
M83 Adult osteomalacia
0.690 0.310 0.000
M82 Osteoporosis in diseases classified elsewhere
0.690 0.310 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.690 0.310 0.000
S61 Open wound of wrist and hand
0.690 0.310 0.000
T92 Sequelae of injuries of upper limb
0.690 0.310 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.690 0.310 0.000
C66 Malignant neoplasm of ureter
0.690 0.310 0.000
C65 Malignant neoplasm of renal pelvis
0.690 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.311 0.000
S27 Injury of other and unspecified intrathoracic organs
0.688 0.312 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.687 0.313 0.000
H61 Other disorders of external ear
0.687 0.313 0.000
C67.6 Ureteric orifice
0.686 0.314 0.000
D03 Melanoma in situ
0.686 0.314 0.000
H80-H83 Diseases of inner ear
0.686 0.314 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.684 0.316 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.684 0.316 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.683 0.317 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.683 0.317 0.000
T39.4 Antirheumatics, not elsewhere classified
0.683 0.317 0.000
T39.2 Pyrazolone derivatives
0.683 0.317 0.000
O45 Premature separation of placenta [abruptio placentae]
0.683 0.317 0.000
O44 Placenta praevia
0.683 0.317 0.000
O41 Other disorders of amniotic fluid and membranes
0.683 0.317 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.683 0.317 0.000
O33 Maternal care for known or suspected disproportion
0.683 0.317 0.000
O31 Complications specific to multiple gestation
0.683 0.317 0.000
J11 Influenza, virus not identified
0.682 0.318 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
S06.5 Traumatic subdural haemorrhage
0.682 0.318 0.000
M20-M25 Other joint disorders
0.681 0.319 0.000
S62 Fracture at wrist and hand level
0.680 0.319 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.680 0.320 0.000
M79.1 Myalgia
0.680 0.320 0.000
F38 Other mood [affective] disorders
0.680 0.320 0.000
F34 Persistent mood [affective] disorders
0.680 0.320 0.000
F30 Manic episode
0.680 0.320 0.000
F39 Unspecified mood [affective] disorder
0.680 0.320 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.680 0.320 0.000
F32.1 Moderate depressive episode
0.679 0.320 0.000
G93 Other disorders of brain
0.679 0.321 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.679 0.321 0.000
J98.8 Other specified respiratory disorders
0.679 0.321 0.000
N30-N39 Other diseases of urinary system
0.678 0.322 0.000
S01.2 Open wound of nose
0.678 0.322 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.677 0.323 0.000
X50-X57 Overexertion, travel and privation
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
W50-W64 Exposure to animate mechanical forces
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V80-V89 Other land transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
S02.4 Fracture of malar and maxillary bones
0.677 0.323 0.000
H73.8 Other specified disorders of tympanic membrane
0.677 0.323 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.676 0.324 0.000
M67 Other disorders of synovium and tendon
0.675 0.325 0.000
O29 Complications of anaesthesia during pregnancy
0.675 0.325 0.000
O28 Abnormal findings on antenatal screening of mother
0.675 0.325 0.000
O24 Diabetes mellitus in pregnancy
0.675 0.325 0.000
O22 Venous complications in pregnancy
0.675 0.325 0.000
O21 Excessive vomiting in pregnancy
0.675 0.325 0.000
O25 Malnutrition in pregnancy
0.675 0.325 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.674 0.326 0.000
M49 Spondylopathies in diseases classified elsewhere
0.673 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.673 0.327 0.000
G30-G32 Other degenerative diseases of the nervous system
0.672 0.328 0.000
Q00-Q07 Congenital malformations of the nervous system
0.671 0.329 0.000
M75.8 Other shoulder lesions
0.669 0.331 0.000
M75.9 Shoulder lesion, unspecified
0.669 0.331 0.000
H92 Otalgia and effusion of ear
0.669 0.331 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.668 0.331 0.000
Q50-Q56 Congenital malformations of genital organs
0.668 0.332 0.000
M05-M14 Inflammatory polyarthropathies
0.667 0.333 0.000
O16 Unspecified maternal hypertension
0.666 0.334 0.000
H90 Conductive and sensorineural hearing loss
0.666 0.334 0.000
C50-C50 Malignant neoplasm of breast
0.666 0.334 0.000
S02.0 Fracture of vault of skull
0.666 0.334 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.665 0.335 0.000
J18.0 Bronchopneumonia, unspecified
0.665 0.335 0.000
N20.2 Calculus of kidney with calculus of ureter
0.665 0.335 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.335 0.000
M79.61 Pain in limb (Shoulder region)
0.665 0.335 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.664 0.336 0.000
C77.4 Inguinal and lower limb lymph nodes
0.664 0.336 0.000
M93 Other osteochondropathies
0.663 0.337 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.662 0.338 0.000
N32 Other disorders of bladder
0.662 0.338 0.000
C67.8 Overlapping lesion of bladder
0.662 0.338 0.000
C67.7 Urachus
0.662 0.338 0.000
C67.5 Bladder neck
0.662 0.338 0.000
C67.3 Anterior wall of bladder
0.662 0.338 0.000
C67.1 Dome of bladder
0.662 0.338 0.000
C67.0 Trigone of bladder
0.662 0.338 0.000
D45 Polycythaemia vera
0.662 0.338 0.000
J96 Respiratory failure, not elsewhere classified
0.662 0.338 0.000
F99-F99 Unspecified mental disorder
0.661 0.338 0.000
M75.2 Bicipital tendinitis
0.659 0.340 0.000
S06.8 Other intracranial injuries
0.659 0.341 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.659 0.341 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.659 0.341 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.658 0.341 0.000
J10 Influenza due to identified influenza virus
0.658 0.342 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.656 0.344 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.656 0.344 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.656 0.344 0.000
M51 Other intervertebral disk disorders
0.656 0.344 0.000
F32.8 Other depressive episodes
0.656 0.344 0.000
F32.0 Mild depressive episode
0.656 0.344 0.000
M79.5 Residual foreign body in soft tissue
0.655 0.345 0.000
M81.8 Other osteoporosis
0.654 0.345 0.000
M81.6 Localised osteoporosis [Lequesne]
0.654 0.345 0.000
M81.5 Idiopathic osteoporosis
0.654 0.345 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.654 0.345 0.000
M81.1 Postoophorectomy osteoporosis
0.654 0.345 0.000
M81.0 Postmenopausal osteoporosis
0.654 0.345 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
O14.9 Preeclampsia, unspecified
0.653 0.347 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.652 0.348 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.651 0.349 0.000
S02.8 Fractures of other skull and facial bones
0.651 0.349 0.000
S02.7 Multiple fractures involving skull and facial bones
0.651 0.349 0.000
S02.5 Fracture of tooth
0.651 0.349 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.651 0.349 0.000
O32.1 Maternal care for breech presentation
0.650 0.350 0.000
W07 Fall involving chair
0.650 0.350 0.000
C77.8 Lymph nodes of multiple regions
0.650 0.350 0.000
J17 Pneumonia in diseases classified elsewhere
0.649 0.350 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.649 0.350 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.649 0.350 0.000
J12 Viral pneumonia, not elsewhere classified
0.649 0.350 0.000
J14 Pneumonia due to Haemophilus influenzae
0.649 0.350 0.000
J09 Influenza due to certain identified influenza virus
0.649 0.350 0.000
M79.67 Pain in limb (Ankle and foot)
0.649 0.351 0.000
M40-M43 Deforming dorsopathies
0.649 0.351 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.648 0.352 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.648 0.352 0.000
H70 Mastoiditis and related conditions
0.648 0.352 0.000
H69 Other disorders of Eustachian tube
0.648 0.352 0.000
H68 Eustachian salpingitis and obstruction
0.648 0.352 0.000
H67 Otitis media in diseases classified elsewhere
0.648 0.352 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.647 0.353 0.000
M46 Other inflammatory spondylopathies
0.647 0.353 0.000
M81.4 Drug-induced osteoporosis
0.646 0.354 0.000
G56 Mononeuropathies of upper limb
0.646 0.354 0.000
F20.9 Schizophrenia, unspecified
0.646 0.354 0.000
M88 Paget's disease of bone [osteitis deformans]
0.646 0.354 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.645 0.354 0.000
F31 Bipolar affective disorder
0.645 0.355 0.000
M79.9 Soft tissue disorder, unspecified
0.645 0.355 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.645 0.355 0.000
M79.3 Panniculitis, unspecified
0.645 0.355 0.000
O36.5 Maternal care for poor foetal growth
0.644 0.356 0.000
J98.6 Disorders of diaphragm
0.644 0.356 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.644 0.356 0.000
J98.3 Compensatory emphysema
0.644 0.356 0.000
J98.2 Interstitial emphysema
0.644 0.356 0.000
S01.1 Open wound of eyelid and periocular area
0.644 0.356 0.000
C67.4 Posterior wall of bladder
0.644 0.356 0.000
T43.9 Psychotropic drug, unspecified
0.643 0.356 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.643 0.356 0.000
T43.6 Psychostimulants with abuse potential
0.643 0.356 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.643 0.356 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.643 0.356 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.643 0.356 0.000
S69 Other and unspecified injuries of wrist and hand
0.643 0.357 0.000
M86 Osteomyelitis
0.643 0.357 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.642 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.642 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.642 0.358 0.000
O02.1 Missed abortion
0.641 0.358 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.641 0.359 0.000
O81 Single delivery by forceps and vacuum extractor
0.641 0.359 0.000
Y40 Systemic antibiotics
0.640 0.360 0.000
J40 Bronchitis, not specified as acute or chronic
0.640 0.360 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.639 0.361 0.000
S65 Injury of blood vessels at wrist and hand level
0.639 0.361 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.638 0.362 0.000
F22 Persistent delusional disorders
0.638 0.362 0.000
Chapter I Certain infectious and parasitic diseases
0.637 0.363 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.636 0.364 0.000
M53 Other dorsopathies, not elsewhere classified
0.635 0.364 0.000
S20 Superficial injury of thorax
0.635 0.365 0.000
H65 Nonsuppurative otitis media
0.635 0.365 0.000
W20-W49 Exposure to inanimate mechanical forces
0.635 0.365 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.635 0.365 0.000
O20.0 Threatened abortion
0.635 0.365 0.000
M54.4 Lumbago with sciatica
0.635 0.365 0.000
S00.0 Superficial injury of scalp
0.634 0.366 0.000
M54.3 Sciatica
0.633 0.367 0.000
Y57 Other and unspecified drugs and medicaments
0.632 0.368 0.000
F03 Unspecified dementia
0.632 0.368 0.000
C51-C58 Malignant neoplasms of female genital organs
0.632 0.368 0.000
N99-N99 Other disorders of the genitourinary system
0.632 0.368 0.000
O80.9 Single spontaneous delivery, unspecified
0.632 0.368 0.000
Q60-Q64 Congenital malformations of the urinary system
0.631 0.368 0.000
O03 Spontaneous abortion
0.631 0.369 0.000
G20-G26 Extrapyramidal and movement disorders
0.631 0.369 0.000
O15 Eclampsia
0.630 0.370 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.630 0.370 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.630 0.370 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.629 0.371 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.629 0.371 0.000
O32.8 Maternal care for other malpresentation of foetus
0.629 0.371 0.000
O32.6 Maternal care for compound presentation
0.629 0.371 0.000
O32.4 Maternal care for high head at term
0.629 0.371 0.000
O32.3 Maternal care for face, brow and chin presentation
0.629 0.371 0.000
O32.0 Maternal care for unstable lie
0.629 0.371 0.000
J60-J70 Lung diseases due to external agents
0.628 0.371 0.000
G54 Nerve root and plexus disorders
0.628 0.371 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.628 0.372 0.000
M54.2 Cervicalgia
0.627 0.373 0.000
M79.7 Fibromyalgia
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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