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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78801169
log Bayes Factor = 14.2444
Chromosome 2   position 167,872,932  (GRCh37) Explore rs78801169 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
C51-C58 Malignant neoplasms of female genital organs
0.990 0.010 0.000
M20-M25 Other joint disorders
0.990 0.010 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.990 0.010 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.981 0.019 0.000
Z93 Artificial opening status
0.973 0.027 0.000
C79 Secondary malignant neoplasm of other sites
0.973 0.027 0.000
C64-C68 Malignant neoplasms of urinary tract
0.971 0.029 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.969 0.031 0.000
C34 Malignant neoplasm of bronchus and lung
0.968 0.032 0.000
M70-M79 Other soft tissue disorders
0.968 0.032 0.000
M20 Acquired deformities of fingers and toes
0.966 0.034 0.000
Z87 Personal history of other diseases and conditions
0.960 0.040 0.000
E70-E90 Metabolic disorders
0.954 0.046 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.949 0.051 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.942 0.058 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.939 0.061 0.000
E65-E68 Obesity and other hyperalimentation
0.939 0.061 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.937 0.063 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.932 0.068 0.000
Z94 Transplanted organ and tissue status
0.931 0.069 0.000
E10.4 With neurological complications
0.931 0.069 0.000
D80-D89 Certain disorders involving the immune mechanism
0.929 0.071 0.000
C56 Malignant neoplasm of ovary
0.927 0.073 0.000
Z60 Problems related to social environment
0.923 0.077 0.000
E10.5 With peripheral circulatory complications
0.919 0.081 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.919 0.081 0.000
C54 Malignant neoplasm of corpus uteri
0.919 0.081 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.919 0.081 0.000
C15-C26 Malignant neoplasms of digestive organs
0.918 0.082 0.000
E86 Volume depletion
0.917 0.083 0.000
E10.2 With renal complications
0.914 0.086 0.000
C67 Malignant neoplasm of bladder
0.912 0.088 0.000
M25 Other joint disorders, not elsewhere classified
0.911 0.089 0.000
M20.4 Other hammer toe(s) (acquired)
0.909 0.091 0.000
C34.9 Bronchus or lung, unspecified
0.906 0.094 0.000
D60-D64 Aplastic and other anaemias
0.906 0.094 0.000
Z60.2 Living alone
0.905 0.095 0.000
Z51 Other medical care
0.900 0.100 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.899 0.101 0.000
A30-A49 Other bacterial diseases
0.897 0.103 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.896 0.104 0.000
E66 Obesity
0.896 0.104 0.000
D86 Sarcoidosis
0.895 0.105 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.894 0.106 0.000
Z85 Personal history of malignant neoplasm
0.893 0.107 0.000
Z94.8 Other transplanted organ and tissue status
0.891 0.109 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.891 0.109 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.881 0.119 0.000
Z93.3 Colostomy status
0.876 0.124 0.000
M20.1 Hallux valgus (acquired)
0.876 0.124 0.000
Z51.3 Blood transfusion without reported diagnosis
0.875 0.125 0.000
M77 Other enthesopathies
0.870 0.130 0.000
C52 Malignant neoplasm of vagina
0.869 0.131 0.000
C54.1 Endometrium
0.868 0.132 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.865 0.135 0.000
Chapter XX External causes of morbidity and mortality
0.863 0.137 0.000
Z93.2 Ileostomy status
0.863 0.137 0.000
Chapter VI Diseases of the nervous system
0.859 0.141 0.000
Z87.1 Personal history of diseases of the digestive system
0.859 0.141 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.858 0.142 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.857 0.143 0.000
Z04 Examination and observation for other reasons
0.856 0.144 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.855 0.145 0.000
M21 Other acquired deformities of limbs
0.854 0.146 0.000
Z83 Family history of other specific disorders
0.853 0.147 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.851 0.149 0.000
E66.9 Obesity, unspecified
0.850 0.150 0.000
Z51.5 Palliative care
0.849 0.151 0.000
E11 Non-insulin-dependent diabetes mellitus
0.844 0.156 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.841 0.159 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.841 0.159 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.839 0.161 0.000
C34.3 Lower lobe, bronchus or lung
0.839 0.161 0.000
C34.1 Upper lobe, bronchus or lung
0.837 0.163 0.000
Z93.6 Other artificial openings of urinary tract status
0.835 0.165 0.000
M31 Other necrotising vasculopathies
0.835 0.165 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.835 0.165 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.834 0.166 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.833 0.167 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.832 0.168 0.000
M72 Fibroblastic disorders
0.832 0.168 0.000
C80 Malignant neoplasm without specification of site
0.829 0.171 0.000
M25.7 Osteophyte
0.829 0.171 0.000
M05-M14 Inflammatory polyarthropathies
0.827 0.173 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.827 0.173 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.827 0.173 0.000
B35-B49 Mycoses
0.824 0.176 0.000
D86.9 Sarcoidosis, unspecified
0.823 0.177 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.822 0.178 0.000
M24 Other specific joint derangements
0.822 0.178 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.821 0.179 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
M71 Other bursopathies
0.816 0.184 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.815 0.185 0.000
D62 Acute posthaemorrhagic anaemia
0.813 0.187 0.000
M20.5 Other deformities of toe(s) (acquired)
0.812 0.188 0.000
B02 Zoster [herpes zoster]
0.812 0.188 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.812 0.188 0.000
Z51.0 Radiotherapy session
0.811 0.189 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.809 0.191 0.000
Z83.5 Family history of eye and ear disorders
0.805 0.195 0.000
M80-M85 Disorders of bone density and structure
0.802 0.198 0.000
E20-E35 Disorders of other endocrine glands
0.801 0.199 0.000
Chapter XXII Codes for special purposes
0.800 0.200 0.000
Z36 Antenatal screening
0.798 0.202 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.795 0.205 0.000
Z92 Personal history of medical treatment
0.794 0.206 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.794 0.206 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.793 0.207 0.000
E50-E64 Other nutritional deficiencies
0.793 0.207 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.786 0.214 0.000
Z04.8 Examination and observation for other specified reasons
0.784 0.216 0.000
C66 Malignant neoplasm of ureter
0.782 0.218 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.780 0.220 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.779 0.221 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.778 0.222 0.000
C92 Myeloid leukaemia
0.777 0.223 0.000
D86.0 Sarcoidosis of lung
0.776 0.224 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.774 0.226 0.000
C34.0 Main bronchus
0.774 0.226 0.000
Z93.0 Tracheostomy status
0.774 0.226 0.000
C91 Lymphoid leukaemia
0.773 0.227 0.000
A40 Streptococcal septicaemia
0.773 0.227 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.773 0.227 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.772 0.228 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.770 0.230 0.000
M10 Gout
0.770 0.230 0.000
B99-B99 Other infectious diseases
0.769 0.231 0.000
C20 Malignant neoplasm of rectum
0.768 0.232 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.767 0.233 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.766 0.234 0.000
A41 Other septicaemia
0.766 0.234 0.000
Z51.9 Medical care, unspecified
0.765 0.235 0.000
Q50-Q56 Congenital malformations of genital organs
0.763 0.237 0.000
M22 Disorders of patella
0.763 0.237 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.762 0.238 0.000
M25.8 Other specified joint disorders
0.761 0.239 0.000
C67.4 Posterior wall of bladder
0.761 0.239 0.000
E10.3 With ophthalmic complications
0.760 0.240 0.000
E11.4 With neurological complications
0.759 0.241 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.757 0.243 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.756 0.244 0.000
Z99.8 Dependence on other enabling machines and devices
0.756 0.244 0.000
M25.0 Haemarthrosis
0.755 0.245 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.754 0.246 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.754 0.246 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.753 0.247 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.752 0.248 0.000
E83 Disorders of mineral metabolism
0.751 0.249 0.000
B25-B34 Other viral diseases
0.749 0.251 0.000
C78.2 Secondary malignant neoplasm of pleura
0.747 0.253 0.000
Z85.6 Personal history of leukaemia
0.746 0.254 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
M20.2 Hallux rigidus
0.744 0.256 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.743 0.257 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.743 0.257 0.000
C67.9 Bladder, unspecified
0.742 0.258 0.000
Z98 Other postsurgical states
0.741 0.259 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.740 0.259 0.000
E13 Other specified diabetes mellitus
0.740 0.260 0.000
M25.3 Other instability of joint
0.740 0.260 0.000
C16 Malignant neoplasm of stomach
0.740 0.260 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.739 0.261 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.738 0.262 0.000
G90-G99 Other disorders of the nervous system
0.736 0.264 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.735 0.264 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.736 0.264 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.735 0.265 0.000
M91-M94 Chondropathies
0.735 0.265 0.000
M31.6 Other giant cell arteritis
0.734 0.266 0.000
C88 Malignant immunoproliferative diseases
0.733 0.267 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.733 0.267 0.000
Q00-Q07 Congenital malformations of the nervous system
0.732 0.268 0.000
Z92.3 Personal history of irradiation
0.731 0.269 0.000
Y95 Nosocomial condition
0.730 0.270 0.000
Z29 Need for other prophylactic measures
0.730 0.270 0.000
M10.9 Gout, unspecified
0.729 0.271 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.728 0.272 0.000
C21 Malignant neoplasm of anus and anal canal
0.727 0.273 0.000
C67.0 Trigone of bladder
0.725 0.275 0.000
E16 Other disorders of pancreatic internal secretion
0.723 0.277 0.000
Z58 Problems related to physical environment
0.722 0.278 0.000
Z51.1 Chemotherapy session for neoplasm
0.722 0.278 0.000
X20-X29 Contact with venomous animals and plants
0.722 0.278 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.722 0.278 0.000
E66.8 Other obesity
0.722 0.278 0.000
E40-E46 Malnutrition
0.721 0.279 0.000
D55-D59 Haemolytic anaemias
0.721 0.279 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.721 0.279 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.720 0.280 0.000
M77.4 Metatarsalgia
0.720 0.280 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.720 0.280 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.719 0.281 0.000
C53 Malignant neoplasm of cervix uteri
0.719 0.281 0.000
E11.0 With coma
0.718 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Z39 Postpartum care and examination
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.713 0.286 0.000
C22.0 Liver cell carcinoma
0.712 0.288 0.000
D86.8 Sarcoidosis of other and combined sites
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
Q80-Q89 Other congenital malformations
0.712 0.288 0.000
M70.4 Prepatellar bursitis
0.711 0.289 0.000
M25.77 Osteophyte (Ankle and foot)
0.710 0.290 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.710 0.290 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.710 0.290 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.710 0.290 0.000
C58 Malignant neoplasm of placenta
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.710 0.290 0.000
E73 Lactose intolerance
0.710 0.290 0.000
B15-B19 Viral hepatitis
0.709 0.290 0.000
C22.9 Liver, unspecified
0.709 0.290 0.000
C51 Malignant neoplasm of vulva
0.709 0.291 0.000
C34.2 Middle lobe, bronchus or lung
0.708 0.292 0.000
M50-M54 Other dorsopathies
0.708 0.292 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.707 0.292 0.000
Z48 Other surgical follow-up care
0.707 0.293 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.707 0.293 0.000
C67.1 Dome of bladder
0.706 0.294 0.000
H65-H75 Diseases of middle ear and mastoid
0.706 0.294 0.000
E10.1 With ketoacidosis
0.706 0.294 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.704 0.296 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.704 0.296 0.000
C32 Malignant neoplasm of larynx
0.704 0.296 0.000
C31 Malignant neoplasm of accessory sinuses
0.704 0.296 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.704 0.296 0.000
C37 Malignant neoplasm of thymus
0.704 0.296 0.000
C33 Malignant neoplasm of trachea
0.704 0.296 0.000
E11.5 With peripheral circulatory complications
0.703 0.297 0.000
C15 Malignant neoplasm of oesophagus
0.703 0.297 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.703 0.297 0.000
M77.0 Medial epicondylitis
0.703 0.297 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.703 0.297 0.000
C67.3 Anterior wall of bladder
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.702 0.298 0.000
M40-M43 Deforming dorsopathies
0.701 0.299 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.701 0.299 0.000
M86-M90 Other osteopathies
0.700 0.300 0.000
M24.1 Other articular cartilage disorders
0.699 0.301 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.699 0.301 0.000
M25.72 Osteophyte (Upper arm)
0.698 0.302 0.000
Z93.9 Artificial opening status, unspecified
0.698 0.302 0.000
Z93.8 Other artificial opening status
0.698 0.302 0.000
C79.6 Secondary malignant neoplasm of ovary
0.697 0.302 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.697 0.302 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.697 0.302 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.698 0.302 0.000
D63.0 Anaemia in neoplastic disease
0.697 0.303 0.000
B37 Candidiasis
0.696 0.304 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.696 0.304 0.000
C65 Malignant neoplasm of renal pelvis
0.696 0.304 0.000
C34.8 Overlapping lesion of bronchus and lung
0.694 0.306 0.000
M76 Enthesopathies of lower limb, excluding foot
0.694 0.306 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.694 0.306 0.000
Z30 Contraceptive management
0.694 0.306 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.692 0.308 0.000
Chapter V Mental and behavioural disorders
0.692 0.308 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.692 0.308 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.309 0.000
B02.9 Zoster without complication
0.689 0.311 0.000
C71 Malignant neoplasm of brain
0.689 0.311 0.000
M20.3 Other deformity of hallux (acquired)
0.688 0.312 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.688 0.312 0.000
Z94.4 Liver transplant status
0.686 0.314 0.000
D46 Myelodysplastic syndromes
0.686 0.314 0.000
C67.2 Lateral wall of bladder
0.685 0.315 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.685 0.315 0.000
D61 Other aplastic anaemias
0.685 0.315 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.684 0.316 0.000
E85 Amyloidosis
0.684 0.316 0.000
E84 Cystic fibrosis
0.684 0.316 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.316 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.316 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.316 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.316 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.316 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.316 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.316 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.316 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.316 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.682 0.318 0.000
Z65 Problems related to other psychosocial circumstances
0.681 0.319 0.000
Z64 Problems related to certain psychosocial circumstances
0.681 0.319 0.000
Z62 Other problems related to upbringing
0.681 0.319 0.000
Z61 Problems related to negative life events in childhood
0.681 0.319 0.000
Z59 Problems related to housing and economic circumstances
0.681 0.319 0.000
Z56 Problems related to employment and unemployment
0.681 0.319 0.000
Z55 Problems related to education and literacy
0.681 0.319 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.680 0.320 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.680 0.320 0.000
M34 Systemic sclerosis
0.679 0.321 0.000
M77.9 Enthesopathy, unspecified
0.679 0.321 0.000
Z03.8 Observation for other suspected diseases and conditions
0.677 0.323 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.677 0.323 0.000
Z89 Acquired absence of limb
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.676 0.324 0.000
H60-H62 Diseases of external ear
0.676 0.324 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.675 0.325 0.000
M21.2 Flexion deformity
0.675 0.325 0.000
Z10 Routine general health check-up of defined subpopulation
0.675 0.325 0.000
Z04.9 Examination and observation for unspecified reason
0.675 0.325 0.000
Z94.7 Corneal transplant status
0.674 0.326 0.000
M21.6 Other acquired deformities of ankle and foot
0.673 0.326 0.000
E67 Other hyperalimentation
0.673 0.327 0.000
E68 Sequelae of hyperalimentation
0.673 0.327 0.000
E65 Localised adiposity
0.673 0.327 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.672 0.328 0.000
M71.3 Other bursal cyst
0.671 0.328 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.670 0.330 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.669 0.331 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.668 0.332 0.000
C95 Leukaemia of unspecified cell type
0.668 0.332 0.000
C94 Other leukaemias of specified cell type
0.668 0.332 0.000
C93 Monocytic leukaemia
0.668 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.668 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.668 0.332 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.667 0.332 0.000
Z94.6 Bone transplant status
0.667 0.332 0.000
Z94.5 Skin transplant status
0.667 0.332 0.000
Z94.3 Heart and lungs transplant status
0.667 0.332 0.000
Z94.2 Lung transplant status
0.667 0.332 0.000
Z94.1 Heart transplant status
0.667 0.332 0.000
C92.0 Acute myeloid leukaemia
0.667 0.333 0.000
B07 Viral warts
0.667 0.333 0.000
Z46 Fitting and adjustment of other devices
0.666 0.334 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.666 0.334 0.000
D84 Other immunodeficiencies
0.666 0.334 0.000
D83 Common variable immunodeficiency
0.666 0.334 0.000
D82 Immunodeficiency associated with other major defects
0.666 0.334 0.000
D81 Combined immunodeficiencies
0.666 0.334 0.000
D80 Immunodeficiency with predominantly antibody defects
0.666 0.334 0.000
M10.96 Gout, unspecified (Lower leg)
0.666 0.334 0.000
C60-C63 Malignant neoplasms of male genital organs
0.666 0.334 0.000
Z87.8 Personal history of other specified conditions
0.665 0.335 0.000
M25.78 Osteophyte (Other)
0.665 0.335 0.000
G58 Other mononeuropathies
0.664 0.336 0.000
G57 Mononeuropathies of lower limb
0.664 0.336 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.663 0.337 0.000
M21.3 Wrist or foot drop (acquired)
0.663 0.337 0.000
B02.2 Zoster with other nervous system involvement
0.662 0.338 0.000
Z60.9 Problem related to social environment, unspecified
0.662 0.338 0.000
Z60.8 Other problems related to social environment
0.662 0.338 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.662 0.338 0.000
Z60.4 Social exclusion and rejection
0.662 0.338 0.000
Z60.3 Acculturation difficulty
0.662 0.338 0.000
Z60.1 Atypical parenting situation
0.662 0.338 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.662 0.338 0.000
C79.2 Secondary malignant neoplasm of skin
0.662 0.338 0.000
E87.3 Alkalosis
0.661 0.339 0.000
C25 Malignant neoplasm of pancreas
0.660 0.340 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.660 0.340 0.000
Z22 Carrier of infectious disease
0.660 0.340 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.660 0.340 0.000
C54.9 Corpus uteri, unspecified
0.659 0.341 0.000
C54.8 Overlapping lesion of corpus uteri
0.659 0.341 0.000
C54.3 Fundus uteri
0.659 0.341 0.000
C54.2 Myometrium
0.659 0.341 0.000
C54.0 Isthmus uteri
0.659 0.341 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.659 0.341 0.000
Q35-Q37 Cleft lip and cleft palate
0.659 0.341 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.659 0.341 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.659 0.341 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.658 0.342 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.658 0.342 0.000
C17 Malignant neoplasm of small intestine
0.658 0.342 0.000
C23 Malignant neoplasm of gallbladder
0.658 0.342 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.658 0.342 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.657 0.343 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.656 0.344 0.000
C22.1 Intrahepatic bile duct carcinoma
0.655 0.345 0.000
E11.1 With ketoacidosis
0.655 0.345 0.000
C67.8 Overlapping lesion of bladder
0.654 0.346 0.000
C67.7 Urachus
0.654 0.346 0.000
C67.5 Bladder neck
0.654 0.346 0.000
C81 Hodgkin's disease
0.653 0.346 0.000
M25.9 Joint disorder, unspecified
0.653 0.347 0.000
M25.2 Flail joint
0.653 0.347 0.000
M25.1 Fistula of joint
0.653 0.347 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.653 0.347 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.651 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.651 0.349 0.000
A40.8 Other streptococcal septicaemia
0.650 0.349 0.000
Z04.5 Examination and observation following other inflicted injury
0.650 0.350 0.000
C67.6 Ureteric orifice
0.649 0.351 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.649 0.351 0.000
Z41 Procedures for purposes other than remedying health state
0.649 0.351 0.000
M77.1 Lateral epicondylitis
0.649 0.351 0.000
D00-D09 In situ neoplasms
0.647 0.353 0.000
Z51.6 Desensitisation to allergens
0.645 0.354 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.645 0.355 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.645 0.355 0.000
Z44 Fitting and adjustment of external prosthetic device
0.644 0.355 0.000
Z29.0 Isolation
0.644 0.356 0.000
Z92.0 Personal history of contraception
0.644 0.356 0.000
A48 Other bacterial diseases, not elsewhere classified
0.643 0.356 0.000
A44 Bartonellosis
0.643 0.356 0.000
A43 Nocardiosis
0.643 0.356 0.000
A42 Actinomycosis
0.643 0.356 0.000
A39 Meningococcal infection
0.643 0.356 0.000
A37 Whooping cough
0.643 0.356 0.000
A36 Diphtheria
0.643 0.356 0.000
A32 Listeriosis
0.643 0.356 0.000
A31 Infection due to other mycobacteria
0.643 0.356 0.000
A30 Leprosy [Hansen's disease]
0.643 0.356 0.000
A46 Erysipelas
0.643 0.356 0.000
A38 Scarlet fever
0.643 0.356 0.000
A35 Other tetanus
0.643 0.356 0.000
A34 Obstetrical tetanus
0.643 0.356 0.000
A33 Tetanus neonatorum
0.643 0.356 0.000
G70-G73 Diseases of myoneural junction and muscle
0.643 0.357 0.000
M79.8 Other specified soft tissue disorders
0.643 0.357 0.000
B02.3 Zoster ocular disease
0.643 0.357 0.000
M25.06 Haemarthrosis (Lower leg)
0.643 0.357 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.643 0.357 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.643 0.357 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.642 0.358 0.000
E66.1 Drug-induced obesity
0.642 0.358 0.000
E66.0 Obesity due to excess calories
0.642 0.358 0.000
D86.3 Sarcoidosis of skin
0.642 0.358 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.642 0.358 0.000
D86.1 Sarcoidosis of lymph nodes
0.642 0.358 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.641 0.359 0.000
B06 Rubella [German measles]
0.641 0.359 0.000
B05 Measles
0.641 0.359 0.000
B01 Varicella [chickenpox]
0.641 0.359 0.000
B00 Herpesviral [herpes simplex] infections
0.641 0.359 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.641 0.359 0.000
B04 Monkeypox
0.641 0.359 0.000
B03 Smallpox
0.641 0.359 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.640 0.360 0.000
E14 Unspecified diabetes mellitus
0.640 0.360 0.000
D41.4 Bladder
0.640 0.360 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.639 0.361 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.639 0.361 0.000
Z09.4 Follow-up examination after treatment of fracture
0.639 0.361 0.000
Z09.3 Follow-up examination after psychotherapy
0.639 0.361 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.639 0.361 0.000
E53 Deficiency of other B group vitamins
0.638 0.362 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.638 0.362 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.638 0.362 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.638 0.362 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.636 0.364 0.000
M70.2 Olecranon bursitis
0.636 0.364 0.000
G59.0 Diabetic mononeuropathy
0.633 0.367 0.000
Z63 Other problems related to primary support group, including family circumstances
0.633 0.367 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.632 0.368 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.632 0.368 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.632 0.368 0.000
C91.1 Chronic lymphocytic leukaemia
0.632 0.368 0.000
M54 Dorsalgia
0.631 0.369 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.631 0.369 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.631 0.369 0.000
M80 Osteoporosis with pathological fracture
0.629 0.370 0.000
B37.0 Candidal stomatitis
0.629 0.371 0.000
G51 Facial nerve disorders
0.628 0.372 0.000
E83.3 Disorders of phosphorus metabolism
0.626 0.374 0.000
D64 Other anaemias
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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