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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79002142
log Bayes Factor = 11.7979
Chromosome 12   position 85,143,591  (GRCh37) Explore rs79002142 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.999 0.001 0.000
C34 Malignant neoplasm of bronchus and lung
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
C79 Secondary malignant neoplasm of other sites
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
C34.9 Bronchus or lung, unspecified
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.979 0.021 0.000
Chapter XI Diseases of the digestive system
0.978 0.022 0.000
M48 Other spondylopathies
0.977 0.023 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.971 0.029 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.965 0.035 0.000
M80-M85 Disorders of bone density and structure
0.965 0.035 0.000
M25 Other joint disorders, not elsewhere classified
0.965 0.035 0.000
K70-K77 Diseases of liver
0.963 0.037 0.000
G30-G32 Other degenerative diseases of the nervous system
0.963 0.037 0.000
M70-M79 Other soft tissue disorders
0.960 0.040 0.000
M48.0 Spinal stenosis
0.960 0.040 0.000
M46 Other inflammatory spondylopathies
0.957 0.043 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.954 0.046 0.000
G90-G99 Other disorders of the nervous system
0.948 0.052 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.945 0.055 0.000
M81 Osteoporosis without pathological fracture
0.943 0.057 0.000
M48.02 Spinal stenosis (Cervical region)
0.942 0.058 0.000
G20-G26 Extrapyramidal and movement disorders
0.942 0.058 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.938 0.062 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.935 0.065 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.934 0.066 0.000
M75 Shoulder lesions
0.933 0.067 0.000
M25.5 Pain in joint
0.930 0.070 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.928 0.072 0.000
M75.4 Impingement syndrome of shoulder
0.927 0.073 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
K74 Fibrosis and cirrhosis of liver
0.918 0.082 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.918 0.082 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.917 0.083 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.917 0.083 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.916 0.084 0.000
R50-R69 General symptoms and signs
0.916 0.084 0.000
W00-W19 Falls
0.914 0.086 0.000
M81.9 Osteoporosis, unspecified
0.913 0.087 0.000
K65-K67 Diseases of peritoneum
0.906 0.094 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.903 0.097 0.000
C34.3 Lower lobe, bronchus or lung
0.897 0.103 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.895 0.105 0.000
R52 Pain, not elsewhere classified
0.894 0.106 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.892 0.108 0.000
G20 Parkinson's disease
0.892 0.108 0.000
G95 Other diseases of spinal cord
0.891 0.109 0.000
M75.3 Calcific tendinitis of shoulder
0.880 0.120 0.000
K13 Other diseases of lip and oral mucosa
0.879 0.121 0.000
R53 Malaise and fatigue
0.879 0.121 0.000
C32 Malignant neoplasm of larynx
0.877 0.123 0.000
K66 Other disorders of peritoneum
0.876 0.124 0.000
M50-M54 Other dorsopathies
0.875 0.125 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.874 0.126 0.000
Y43 Primarily systemic agents
0.872 0.128 0.000
C34.1 Upper lobe, bronchus or lung
0.870 0.130 0.000
K76 Other diseases of liver
0.866 0.134 0.000
C79.2 Secondary malignant neoplasm of skin
0.866 0.134 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.866 0.134 0.000
Y57 Other and unspecified drugs and medicaments
0.860 0.140 0.000
M25.7 Osteophyte
0.859 0.141 0.000
K66.0 Peritoneal adhesions
0.859 0.141 0.000
W19 Unspecified fall
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.851 0.149 0.000
K72 Hepatic failure, not elsewhere classified
0.851 0.149 0.000
M86-M90 Other osteopathies
0.848 0.152 0.000
S60-S69 Injuries to the wrist and hand
0.846 0.154 0.000
C34.0 Main bronchus
0.846 0.154 0.000
R52.1 Chronic intractable pain
0.845 0.155 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.842 0.158 0.000
R47-R49 Symptoms and signs involving speech and voice
0.841 0.159 0.000
K07 Dentofacial anomalies [including malocclusion]
0.838 0.162 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.837 0.163 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.836 0.164 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.835 0.165 0.000
M31 Other necrotising vasculopathies
0.829 0.171 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.829 0.171 0.000
K11 Diseases of salivary glands
0.828 0.172 0.000
R50 Fever of unknown origin
0.826 0.174 0.000
Y52 Agents primarily affecting the cardiovascular system
0.824 0.176 0.000
K50-K52 Noninfective enteritis and colitis
0.824 0.176 0.000
D00-D09 In situ neoplasms
0.821 0.179 0.000
M91-M94 Chondropathies
0.821 0.179 0.000
K74.6 Other and unspecified cirrhosis of liver
0.820 0.180 0.000
T93 Sequelae of injuries of lower limb
0.820 0.180 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.817 0.183 0.000
M24 Other specific joint derangements
0.815 0.185 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.815 0.185 0.000
S50-S59 Injuries to the elbow and forearm
0.811 0.189 0.000
M25.8 Other specified joint disorders
0.811 0.189 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.810 0.190 0.000
G90 Disorders of autonomic nervous system
0.809 0.191 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.804 0.196 0.000
K74.5 Biliary cirrhosis, unspecified
0.804 0.196 0.000
G24 Dystonia
0.803 0.197 0.000
R52.9 Pain, unspecified
0.801 0.199 0.000
Chapter X Diseases of the respiratory system
0.798 0.202 0.000
M25.54 Pain in joint (Hand)
0.798 0.202 0.000
M45 Ankylosing spondylitis
0.798 0.202 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.797 0.203 0.000
T66-T78 Other and unspecified effects of external causes
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.794 0.206 0.000
W19.2 School, other institution and public administrative area
0.794 0.206 0.000
K52 Other non-infective gastro-enteritis and colitis
0.792 0.208 0.000
W50-W64 Exposure to animate mechanical forces
0.790 0.210 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.787 0.212 0.000
T79-T79 Certain early complications of trauma
0.787 0.213 0.000
M47 Spondylosis
0.786 0.214 0.000
K07.6 Temporomandibular joint disorders
0.785 0.215 0.000
K05 Gingivitis and periodontal diseases
0.783 0.217 0.000
T90 Sequelae of injuries of head
0.783 0.217 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.783 0.217 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.782 0.218 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
G95.2 Cord compression, unspecified
0.777 0.223 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.777 0.223 0.000
K12 Stomatitis and related lesions
0.776 0.224 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.776 0.224 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.775 0.224 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.775 0.225 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.775 0.225 0.000
M71 Other bursopathies
0.773 0.227 0.000
M77 Other enthesopathies
0.772 0.228 0.000
M54 Dorsalgia
0.771 0.229 0.000
R54 Senility
0.769 0.231 0.000
M48.09 Spinal stenosis (Site unspecified)
0.768 0.231 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.768 0.232 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.768 0.232 0.000
Y57.9 Drug or medicament, unspecified
0.766 0.234 0.000
R21 Rash and other nonspecific skin eruption
0.765 0.235 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
G30 Alzheimer's disease
0.764 0.236 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.763 0.237 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.762 0.238 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.762 0.238 0.000
J90-J94 Other diseases of pleura
0.761 0.239 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.760 0.240 0.000
R58 Haemorrhage, not elsewhere classified
0.760 0.240 0.000
C15-C26 Malignant neoplasms of digestive organs
0.759 0.241 0.000
S51 Open wound of forearm
0.759 0.241 0.000
R50.9 Fever, unspecified
0.758 0.242 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.758 0.242 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.756 0.244 0.000
G93 Other disorders of brain
0.756 0.244 0.000
M21 Other acquired deformities of limbs
0.755 0.245 0.000
G31.8 Other specified degenerative diseases of nervous system
0.754 0.246 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.753 0.247 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.753 0.247 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.751 0.249 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.751 0.249 0.000
M65-M68 Disorders of synovium and tendon
0.750 0.250 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.749 0.251 0.000
M81.2 Osteoporosis of disuse
0.749 0.251 0.000
M25.57 Pain in joint (Ankle and foot)
0.749 0.251 0.000
M40-M43 Deforming dorsopathies
0.745 0.255 0.000
C09 Malignant neoplasm of tonsil
0.745 0.255 0.000
V40-V49 Car occupant injured in transport accident
0.745 0.255 0.000
W17 Other fall from one level to another
0.744 0.255 0.000
C01 Malignant neoplasm of base of tongue
0.744 0.256 0.000
M81.4 Drug-induced osteoporosis
0.744 0.256 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.743 0.257 0.000
K81 Cholecystitis
0.743 0.257 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.743 0.257 0.000
R57 Shock, not elsewhere classified
0.742 0.258 0.000
C34.2 Middle lobe, bronchus or lung
0.741 0.258 0.000
M80 Osteoporosis with pathological fracture
0.741 0.259 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.740 0.260 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.740 0.260 0.000
K73 Chronic hepatitis, not elsewhere classified
0.739 0.261 0.000
V80-V89 Other land transport accidents
0.738 0.262 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.737 0.263 0.000
C64-C68 Malignant neoplasms of urinary tract
0.737 0.263 0.000
M23 Internal derangement of knee
0.736 0.264 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.735 0.265 0.000
D41.4 Bladder
0.732 0.268 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.732 0.268 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
T91 Sequelae of injuries of neck and trunk
0.730 0.270 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.727 0.273 0.000
W19.3 Sports and athletics area
0.726 0.274 0.000
K76.9 Liver disease, unspecified
0.725 0.275 0.000
K72.0 Acute and subacute hepatic failure
0.724 0.276 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.722 0.277 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.722 0.278 0.000
G70-G73 Diseases of myoneural junction and muscle
0.722 0.278 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.722 0.278 0.000
G95.1 Vascular myelopathies
0.721 0.279 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.720 0.280 0.000
S20-S29 Injuries to the thorax
0.720 0.280 0.000
J20-J22 Other acute lower respiratory infections
0.720 0.280 0.000
K11.5 Sialolithiasis
0.720 0.280 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.718 0.282 0.000
Y43.3 Other antineoplastic drugs
0.717 0.283 0.000
S00-S09 Injuries to the head
0.717 0.283 0.000
J92 Pleural plaque
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
G95.9 Disease of spinal cord, unspecified
0.717 0.283 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.717 0.283 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.717 0.283 0.000
C31 Malignant neoplasm of accessory sinuses
0.717 0.283 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.717 0.283 0.000
C37 Malignant neoplasm of thymus
0.717 0.283 0.000
C33 Malignant neoplasm of trachea
0.717 0.283 0.000
C32.0 Glottis
0.716 0.284 0.000
C34.8 Overlapping lesion of bronchus and lung
0.716 0.284 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.716 0.284 0.000
Chapter XXI Factors influencing health status and contact with health services
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
M50 Cervical disk disorders
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S62 Fracture at wrist and hand level
0.715 0.285 0.000
C79.6 Secondary malignant neoplasm of ovary
0.713 0.287 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
M90 Osteopathies in diseases classified elsewhere
0.713 0.287 0.000
C80 Malignant neoplasm without specification of site
0.712 0.288 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.711 0.289 0.000
M25.76 Osteophyte (Lower leg)
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
R49 Voice disturbances
0.708 0.292 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
K74.3 Primary biliary cirrhosis
0.705 0.295 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.705 0.295 0.000
Y43.1 Antineoplastic antimetabolites
0.705 0.295 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.704 0.296 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
Q50-Q56 Congenital malformations of genital organs
0.703 0.297 0.000
M34 Systemic sclerosis
0.702 0.298 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.702 0.298 0.000
C77.0 Lymph nodes of head, face and neck
0.702 0.298 0.000
R27 Other lack of coordination
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.298 0.000
Y58 Bacterial vaccines
0.702 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.702 0.298 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.702 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.702 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
M25.74 Osteophyte (Hand)
0.701 0.299 0.000
G95.0 Syringomyelia and syringobulbia
0.701 0.299 0.000
M48.9 Spondylopathy, unspecified
0.701 0.299 0.000
M48.8 Other specified spondylopathies
0.701 0.299 0.000
M48.4 Fatigue fracture of vertebra
0.701 0.299 0.000
M48.3 Traumatic spondylopathy
0.701 0.299 0.000
M48.2 Kissing spine
0.701 0.299 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.299 0.000
M33 Dermatopolymyositis
0.700 0.299 0.000
M32 Systemic lupus erythematosus
0.700 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.700 0.299 0.000
K76.8 Other specified diseases of liver
0.698 0.302 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
K72.9 Hepatic failure, unspecified
0.697 0.303 0.000
M85 Other disorders of bone density and structure
0.697 0.303 0.000
T98 Sequelae of other and unspecified effects of external causes
0.697 0.303 0.000
M54.9 Dorsalgia, unspecified
0.696 0.304 0.000
K00 Disorders of tooth development and eruption
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.304 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.693 0.306 0.000
E20-E35 Disorders of other endocrine glands
0.694 0.306 0.000
C32.9 Larynx, unspecified
0.693 0.307 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.692 0.307 0.000
C32.1 Supraglottis
0.692 0.308 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.692 0.308 0.000
M83 Adult osteomalacia
0.692 0.308 0.000
M82 Osteoporosis in diseases classified elsewhere
0.692 0.308 0.000
S64 Injury of nerves at wrist and hand level
0.692 0.308 0.000
M25.3 Other instability of joint
0.692 0.308 0.000
M25.2 Flail joint
0.692 0.308 0.000
M25.1 Fistula of joint
0.692 0.308 0.000
M25.0 Haemarthrosis
0.692 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.691 0.309 0.000
Y43.4 Immunosuppressive agents
0.691 0.309 0.000
K77 Liver disorders in diseases classified elsewhere
0.691 0.309 0.000
K71 Toxic liver disease
0.691 0.309 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.691 0.309 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.691 0.309 0.000
D44.7 Aortic body and other paraganglia
0.690 0.310 0.000
S32 Fracture of lumbar spine and pelvis
0.690 0.310 0.000
K81.1 Chronic cholecystitis
0.690 0.310 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.688 0.312 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.688 0.312 0.000
M48.04 Spinal stenosis (Thoracic region)
0.688 0.312 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.688 0.312 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.688 0.312 0.000
M25.84 Other specified joint disorders (Hand)
0.687 0.313 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.687 0.313 0.000
M46.8 Other specified inflammatory spondylopathies
0.686 0.314 0.000
M46.5 Other infective spondylopathies
0.686 0.314 0.000
M46.4 Discitis, unspecified
0.686 0.314 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.686 0.314 0.000
M46.2 Osteomyelitis of vertebra
0.686 0.314 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.686 0.314 0.000
M46.0 Spinal enthesopathy
0.686 0.314 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.686 0.314 0.000
E40-E46 Malnutrition
0.685 0.315 0.000
K09 Cysts of oral region, not elsewhere classified
0.685 0.315 0.000
M25.52 Pain in joint (Upper arm)
0.684 0.316 0.000
Z51.5 Palliative care
0.684 0.316 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.684 0.316 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.684 0.316 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.683 0.317 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.682 0.318 0.000
R23 Other skin changes
0.682 0.318 0.000
K74.0 Hepatic fibrosis
0.682 0.318 0.000
M81.98 Osteoporosis, unspecified (Other)
0.681 0.318 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.681 0.319 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.681 0.319 0.000
Z51 Other medical care
0.680 0.320 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.680 0.320 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.680 0.320 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.680 0.320 0.000
G92 Toxic encephalopathy
0.680 0.320 0.000
R47 Speech disturbances, not elsewhere classified
0.680 0.320 0.000
M31.6 Other giant cell arteritis
0.679 0.321 0.000
S51.0 Open wound of elbow
0.679 0.321 0.000
M89 Other disorders of bone
0.679 0.321 0.000
M47.9 Spondylosis, unspecified
0.679 0.321 0.000
G24.5 Blepharospasm
0.678 0.321 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.678 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.678 0.322 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.678 0.322 0.000
T92 Sequelae of injuries of upper limb
0.678 0.322 0.000
K03 Other diseases of hard tissues of teeth
0.678 0.322 0.000
S67 Crushing injury of wrist and hand
0.677 0.323 0.000
C10 Malignant neoplasm of oropharynx
0.677 0.323 0.000
M81.8 Other osteoporosis
0.676 0.324 0.000
M81.6 Localised osteoporosis [Lequesne]
0.676 0.324 0.000
M81.5 Idiopathic osteoporosis
0.676 0.324 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.676 0.324 0.000
M81.1 Postoophorectomy osteoporosis
0.676 0.324 0.000
M81.0 Postmenopausal osteoporosis
0.676 0.324 0.000
G23 Other degenerative diseases of basal ganglia
0.676 0.324 0.000
G21 Secondary Parkinsonism
0.676 0.324 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.676 0.324 0.000
G22 Parkinsonism in diseases classified elsewhere
0.676 0.324 0.000
K81.0 Acute cholecystitis
0.675 0.325 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.675 0.325 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.674 0.325 0.000
M25.9 Joint disorder, unspecified
0.674 0.325 0.000
M94 Other disorders of cartilage
0.674 0.326 0.000
M23.3 Other meniscus derangements
0.672 0.328 0.000
R68 Other general symptoms and signs
0.671 0.329 0.000
D04 Carcinoma in situ of skin
0.671 0.329 0.000
K76.7 Hepatorenal syndrome
0.670 0.329 0.000
T95 Sequelae of burns, corrosions and frostbite
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
G31.2 Degeneration of nervous system due to alcohol
0.670 0.330 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.670 0.330 0.000
G31.0 Circumscribed brain atrophy
0.670 0.330 0.000
R52.0 Acute pain
0.669 0.331 0.000
M75.8 Other shoulder lesions
0.669 0.331 0.000
J22 Unspecified acute lower respiratory infection
0.668 0.332 0.000
W08 Fall involving other furniture
0.668 0.332 0.000
M25.58 Pain in joint (Other)
0.667 0.333 0.000
K05.6 Periodontal disease, unspecified
0.666 0.334 0.000
C25 Malignant neoplasm of pancreas
0.666 0.334 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.665 0.335 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.665 0.335 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.665 0.335 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.665 0.335 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.665 0.335 0.000
C07 Malignant neoplasm of parotid gland
0.665 0.335 0.000
W06 Fall involving bed
0.665 0.335 0.000
M31.3 Wegener's granulomatosis
0.664 0.336 0.000
W10 Fall on and from stairs and steps
0.664 0.336 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.664 0.336 0.000
M25.53 Pain in joint (Forearm)
0.663 0.337 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.663 0.337 0.000
D09 Carcinoma in situ of other and unspecified sites
0.662 0.338 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.339 0.000
Z45 Adjustment and management of implanted device
0.661 0.339 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.661 0.339 0.000
W20-W49 Exposure to inanimate mechanical forces
0.660 0.340 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.659 0.341 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.659 0.341 0.000
K74.4 Secondary biliary cirrhosis
0.658 0.341 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.658 0.341 0.000
K74.1 Hepatic sclerosis
0.658 0.341 0.000
E55 Vitamin D deficiency
0.658 0.342 0.000
K08 Other disorders of teeth and supporting structures
0.658 0.342 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.658 0.342 0.000
W19.4 Street and highway
0.658 0.342 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.658 0.342 0.000
S37 Injury of urinary and pelvic organs
0.658 0.342 0.000
S36 Injury of intra-abdominal organs
0.658 0.342 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.658 0.342 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.658 0.342 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.658 0.342 0.000
S31 Open wound of abdomen, lower back and pelvis
0.658 0.342 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.657 0.343 0.000
M24.5 Contracture of joint
0.657 0.343 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.657 0.343 0.000
R62 Lack of expected normal physiological development
0.657 0.343 0.000
R64 Cachexia
0.657 0.343 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.656 0.344 0.000
W18 Other fall on same level
0.655 0.345 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.655 0.345 0.000
W15 Fall from cliff
0.655 0.345 0.000
W14 Fall from tree
0.655 0.345 0.000
W12 Fall on and from scaffolding
0.655 0.345 0.000
W11 Fall on and from ladder
0.655 0.345 0.000
W09 Fall involving playground equipment
0.655 0.345 0.000
W05 Fall involving wheelchair
0.655 0.345 0.000
W04 Fall while being carried or supported by other persons
0.655 0.345 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.655 0.345 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.655 0.345 0.000
W00 Fall on same level involving ice and snow
0.655 0.345 0.000
J92.9 Pleural plaque without asbestos
0.655 0.345 0.000
M77.1 Lateral epicondylitis
0.654 0.346 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.654 0.346 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.654 0.346 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.654 0.346 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.654 0.346 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.654 0.346 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.654 0.346 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.654 0.346 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.654 0.346 0.000
D03 Melanoma in situ
0.654 0.346 0.000
K11.8 Other diseases of salivary glands
0.653 0.347 0.000
T78 Adverse effects, not elsewhere classified
0.653 0.347 0.000
J94 Other pleural conditions
0.651 0.349 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.650 0.350 0.000
Y40 Systemic antibiotics
0.649 0.351 0.000
C78.2 Secondary malignant neoplasm of pleura
0.649 0.351 0.000
M25.72 Osteophyte (Upper arm)
0.649 0.351 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.648 0.352 0.000
C78.0 Secondary malignant neoplasm of lung
0.647 0.353 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.647 0.353 0.000
K11.1 Hypertrophy of salivary gland
0.646 0.354 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.646 0.354 0.000
G96 Other disorders of central nervous system
0.646 0.354 0.000
R26 Abnormalities of gait and mobility
0.646 0.354 0.000
S12 Fracture of neck
0.645 0.354 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.645 0.355 0.000
R52.2 Other chronic pain
0.644 0.356 0.000
M67 Other disorders of synovium and tendon
0.644 0.356 0.000
G90.2 Horner's syndrome
0.643 0.357 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.643 0.357 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.642 0.358 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.642 0.358 0.000
C13 Malignant neoplasm of hypopharynx
0.642 0.358 0.000
C11 Malignant neoplasm of nasopharynx
0.642 0.358 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.642 0.358 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.642 0.358 0.000
C05 Malignant neoplasm of palate
0.642 0.358 0.000
C04 Malignant neoplasm of floor of mouth
0.642 0.358 0.000
C03 Malignant neoplasm of gum
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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