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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79365858
log Bayes Factor = 17.7509
Chromosome 5   position 155,222,667  (GRCh37) Explore rs79365858 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
C78.7 Secondary malignant neoplasm of liver
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
C78.0 Secondary malignant neoplasm of lung
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
C79 Secondary malignant neoplasm of other sites
0.989 0.011 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.986 0.014 0.000
J20-J22 Other acute lower respiratory infections
0.985 0.015 0.000
J22 Unspecified acute lower respiratory infection
0.982 0.018 0.000
Chapter XXI Factors influencing health status and contact with health services
0.978 0.022 0.000
M80-M85 Disorders of bone density and structure
0.978 0.022 0.000
M05-M14 Inflammatory polyarthropathies
0.977 0.023 0.000
B95-B98 Bacterial, viral and other infectious agents
0.969 0.031 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.968 0.032 0.000
M06 Other rheumatoid arthritis
0.967 0.033 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.966 0.034 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.964 0.036 0.000
M06.9 Rheumatoid arthritis, unspecified
0.960 0.040 0.000
Z51 Other medical care
0.956 0.044 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.953 0.047 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.953 0.047 0.000
S60-S69 Injuries to the wrist and hand
0.952 0.048 0.000
M81 Osteoporosis without pathological fracture
0.948 0.052 0.000
M70-M79 Other soft tissue disorders
0.947 0.053 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.943 0.057 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.943 0.057 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.940 0.060 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
L57.0 Actinic keratosis
0.928 0.072 0.000
M81.9 Osteoporosis, unspecified
0.926 0.074 0.000
S00-S09 Injuries to the head
0.921 0.079 0.000
D00-D09 In situ neoplasms
0.917 0.083 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.917 0.083 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.915 0.085 0.000
Chapter VI Diseases of the nervous system
0.914 0.086 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.914 0.086 0.000
Chapter V Mental and behavioural disorders
0.914 0.086 0.000
M20-M25 Other joint disorders
0.913 0.087 0.000
M50-M54 Other dorsopathies
0.910 0.090 0.000
Z51.2 Other chemotherapy
0.908 0.092 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.907 0.093 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.906 0.094 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.905 0.095 0.000
M25 Other joint disorders, not elsewhere classified
0.900 0.100 0.000
M45-M49 Spondylopathies
0.898 0.102 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.896 0.104 0.000
Z51.0 Radiotherapy session
0.895 0.105 0.000
T66-T78 Other and unspecified effects of external causes
0.894 0.106 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.892 0.108 0.000
B35-B49 Mycoses
0.883 0.117 0.000
M25.5 Pain in joint
0.882 0.118 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.881 0.119 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.878 0.122 0.000
L90 Atrophic disorders of skin
0.878 0.122 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.877 0.123 0.000
S62 Fracture at wrist and hand level
0.876 0.124 0.000
Z51.8 Other specified medical care
0.876 0.124 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.875 0.125 0.000
M79.8 Other specified soft tissue disorders
0.873 0.127 0.000
J90-J94 Other diseases of pleura
0.872 0.128 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.869 0.131 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.869 0.131 0.000
M25.56 Pain in joint (Lower leg)
0.866 0.134 0.000
M84 Disorders of continuity of bone
0.865 0.135 0.000
L98.0 Pyogenic granuloma
0.864 0.136 0.000
M51 Other intervertebral disk disorders
0.862 0.138 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.862 0.138 0.000
C64-C68 Malignant neoplasms of urinary tract
0.861 0.139 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
C78.2 Secondary malignant neoplasm of pleura
0.856 0.144 0.000
Y42.7 Androgens and anabolic congeners
0.856 0.144 0.000
M48 Other spondylopathies
0.854 0.146 0.000
W20-W49 Exposure to inanimate mechanical forces
0.852 0.148 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.847 0.153 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.847 0.153 0.000
D10-D36 Benign neoplasms
0.842 0.158 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.841 0.159 0.000
Z50 Care involving use of rehabilitation procedures
0.834 0.166 0.000
Q60-Q64 Congenital malformations of the urinary system
0.834 0.166 0.000
Z40 Prophylactic surgery
0.832 0.168 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.831 0.169 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.828 0.172 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.828 0.172 0.000
D09 Carcinoma in situ of other and unspecified sites
0.828 0.172 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.825 0.175 0.000
A30-A49 Other bacterial diseases
0.824 0.176 0.000
L03 Cellulitis
0.823 0.177 0.000
W00-W19 Falls
0.823 0.177 0.000
M48.0 Spinal stenosis
0.822 0.178 0.000
X60-X84 Intentional self-harm
0.822 0.178 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.821 0.179 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.819 0.180 0.000
M77 Other enthesopathies
0.819 0.181 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.819 0.181 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.818 0.182 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
D25 Leiomyoma of uterus
0.815 0.185 0.000
V10-V19 Pedal cyclist injured in transport accident
0.812 0.188 0.000
D05 Carcinoma in situ of breast
0.812 0.188 0.000
S61 Open wound of wrist and hand
0.808 0.192 0.000
Z46 Fitting and adjustment of other devices
0.808 0.192 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.808 0.192 0.000
M25.51 Pain in joint (Shoulder region)
0.805 0.195 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.803 0.197 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.802 0.198 0.000
M51.2 Other specified intervertebral disk displacement
0.800 0.200 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.799 0.201 0.000
C71 Malignant neoplasm of brain
0.795 0.205 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.795 0.205 0.000
F60-F69 Disorders of adult personality and behaviour
0.794 0.206 0.000
L60-L75 Disorders of skin appendages
0.792 0.208 0.000
Z22 Carrier of infectious disease
0.790 0.209 0.000
S06 Intracranial injury
0.790 0.210 0.000
Z52 Donors of organs and tissues
0.788 0.212 0.000
J09-J18 Influenza and pneumonia
0.788 0.212 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.787 0.213 0.000
C80 Malignant neoplasm without specification of site
0.787 0.213 0.000
G57 Mononeuropathies of lower limb
0.787 0.213 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.785 0.215 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.784 0.216 0.000
M21 Other acquired deformities of limbs
0.783 0.217 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.782 0.217 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.780 0.220 0.000
M48.06 Spinal stenosis (Lumbar region)
0.780 0.220 0.000
J90 Pleural effusion, not elsewhere classified
0.779 0.221 0.000
Z63 Other problems related to primary support group, including family circumstances
0.778 0.222 0.000
Z50.5 Speech therapy
0.777 0.223 0.000
T78 Adverse effects, not elsewhere classified
0.777 0.223 0.000
M34 Systemic sclerosis
0.776 0.224 0.000
M65-M68 Disorders of synovium and tendon
0.776 0.224 0.000
A00-A09 Intestinal infectious diseases
0.774 0.226 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.772 0.228 0.000
S62.5 Fracture of thumb
0.769 0.231 0.000
J95-J99 Other diseases of the respiratory system
0.767 0.233 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.766 0.234 0.000
B15-B19 Viral hepatitis
0.765 0.234 0.000
D25.0 Submucous leiomyoma of uterus
0.765 0.235 0.000
Z51.5 Palliative care
0.764 0.236 0.000
D09.0 Bladder
0.764 0.236 0.000
L90.0 Lichen sclerosus et atrophicus
0.763 0.237 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.762 0.238 0.000
S10-S19 Injuries to the neck
0.761 0.239 0.000
M05 Seropositive rheumatoid arthritis
0.761 0.239 0.000
Y57 Other and unspecified drugs and medicaments
0.760 0.240 0.000
Y44 Agents primarily affecting blood constituents
0.758 0.242 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.757 0.243 0.000
V20-V29 Motorcycle rider injured in transport accident
0.757 0.243 0.000
G90-G99 Other disorders of the nervous system
0.755 0.245 0.000
Q61 Cystic kidney disease
0.754 0.246 0.000
S05 Injury of eye and orbit
0.754 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.752 0.247 0.000
D36 Benign neoplasm of other and unspecified sites
0.751 0.249 0.000
C67 Malignant neoplasm of bladder
0.749 0.251 0.000
B37 Candidiasis
0.748 0.252 0.000
M06.4 Inflammatory polyarthropathy
0.747 0.253 0.000
D24 Benign neoplasm of breast
0.746 0.254 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.746 0.254 0.000
F30-F39 Mood [affective] disorders
0.745 0.255 0.000
D23 Other benign neoplasms of skin
0.744 0.256 0.000
Y52 Agents primarily affecting the cardiovascular system
0.744 0.256 0.000
S01 Open wound of head
0.744 0.256 0.000
M25.57 Pain in joint (Ankle and foot)
0.743 0.257 0.000
F80-F89 Disorders of psychological development
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
Z48 Other surgical follow-up care
0.739 0.261 0.000
T68 Hypothermia
0.739 0.261 0.000
S60 Superficial injury of wrist and hand
0.739 0.261 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.739 0.261 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.738 0.262 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.738 0.262 0.000
L91 Hypertrophic disorders of skin
0.737 0.263 0.000
L50-L54 Urticaria and erythema
0.737 0.263 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.737 0.263 0.000
M25.7 Osteophyte
0.737 0.263 0.000
Z54 Convalescence
0.736 0.264 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.735 0.265 0.000
B35 Dermatophytosis
0.735 0.265 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.735 0.265 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.734 0.266 0.000
Q80-Q89 Other congenital malformations
0.734 0.266 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.733 0.267 0.000
Z51.3 Blood transfusion without reported diagnosis
0.733 0.267 0.000
M91-M94 Chondropathies
0.731 0.269 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.730 0.270 0.000
D25.1 Intramural leiomyoma of uterus
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.727 0.273 0.000
L82 Seborrhoeic keratosis
0.726 0.274 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.726 0.274 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.726 0.274 0.000
L85 Other epidermal thickening
0.724 0.276 0.000
S40-S49 Injuries to the shoulder and upper arm
0.724 0.276 0.000
Z42 Follow-up care involving plastic surgery
0.723 0.276 0.000
L93 Lupus erythematosus
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
S62.6 Fracture of other finger
0.723 0.277 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.721 0.279 0.000
D41.4 Bladder
0.720 0.280 0.000
J93 Pneumothorax
0.719 0.281 0.000
G57.6 Lesion of plantar nerve
0.719 0.281 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.717 0.283 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.715 0.284 0.000
S02 Fracture of skull and facial bones
0.715 0.285 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
M25.4 Effusion of joint
0.714 0.286 0.000
M79.0 Rheumatism, unspecified
0.713 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
Y00-Y09 Assault
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.286 0.000
X10-X19 Contact with heat and hot substances
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V80-V89 Other land transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.713 0.287 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.713 0.287 0.000
L94 Other localised connective tissue disorders
0.713 0.287 0.000
L87 Transepidermal elimination disorders
0.713 0.287 0.000
L88 Pyoderma gangrenosum
0.713 0.287 0.000
L86 Keratoderma in diseases classified elsewhere
0.713 0.287 0.000
L83 Acanthosis nigricans
0.713 0.287 0.000
L80 Vitiligo
0.713 0.287 0.000
M70.6 Trochanteric bursitis
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.287 0.000
B65-B83 Helminthiases
0.712 0.287 0.000
B50-B64 Protozoal diseases
0.712 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.287 0.000
A75-A79 Rickettsioses
0.712 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.287 0.000
A65-A69 Other spirochaetal diseases
0.712 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.287 0.000
A15-A19 Tuberculosis
0.712 0.287 0.000
Z63.4 Disappearance and death of family member
0.711 0.289 0.000
M85 Other disorders of bone density and structure
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.290 0.000
C79.6 Secondary malignant neoplasm of ovary
0.709 0.291 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.709 0.291 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
F60 Specific personality disorders
0.709 0.291 0.000
M11 Other crystal arthropathies
0.708 0.292 0.000
C69 Malignant neoplasm of eye and adnexa
0.708 0.292 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.707 0.293 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.707 0.293 0.000
L98.5 Mucinosis of skin
0.707 0.293 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.707 0.293 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.707 0.293 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.707 0.293 0.000
L98.1 Factitial dermatitis
0.707 0.293 0.000
B25-B34 Other viral diseases
0.707 0.293 0.000
S64 Injury of nerves at wrist and hand level
0.706 0.293 0.000
D25.2 Subserosal leiomyoma of uterus
0.706 0.294 0.000
J21 Acute bronchiolitis
0.706 0.294 0.000
J20 Acute bronchitis
0.706 0.294 0.000
M24 Other specific joint derangements
0.706 0.294 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.705 0.295 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.705 0.295 0.000
J84 Other interstitial pulmonary diseases
0.705 0.295 0.000
L03.3 Cellulitis of trunk
0.704 0.296 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.703 0.297 0.000
J00-J06 Acute upper respiratory infections
0.702 0.298 0.000
M83 Adult osteomalacia
0.701 0.299 0.000
M82 Osteoporosis in diseases classified elsewhere
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.700 0.300 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.700 0.300 0.000
M08 Juvenile arthritis
0.700 0.300 0.000
Q61.3 Polycystic kidney, unspecified
0.700 0.300 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.698 0.302 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.697 0.303 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.697 0.303 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.697 0.303 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.697 0.303 0.000
L90.5 Scar conditions and fibrosis of skin
0.697 0.303 0.000
Y95 Nosocomial condition
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.696 0.303 0.000
L89 Decubitus ulcer
0.696 0.304 0.000
S67 Crushing injury of wrist and hand
0.696 0.304 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.696 0.304 0.000
C79.2 Secondary malignant neoplasm of skin
0.695 0.305 0.000
M48.02 Spinal stenosis (Cervical region)
0.695 0.305 0.000
T78.4 Allergy, unspecified
0.695 0.305 0.000
Z44 Fitting and adjustment of external prosthetic device
0.694 0.306 0.000
D41.0 Kidney
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.693 0.307 0.000
M06.8 Other specified rheumatoid arthritis
0.693 0.307 0.000
M06.3 Rheumatoid nodule
0.693 0.307 0.000
M06.2 Rheumatoid bursitis
0.693 0.307 0.000
M06.1 Adult-onset Still's disease
0.693 0.307 0.000
S09 Other and unspecified injuries of head
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.692 0.307 0.000
Y58 Bacterial vaccines
0.692 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.692 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.692 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.692 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.692 0.307 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.692 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.692 0.307 0.000
S62.50 Fracture of thumb (closed)
0.692 0.308 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.691 0.308 0.000
L58 Radiodermatitis
0.691 0.308 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.691 0.308 0.000
L55 Sunburn
0.691 0.308 0.000
L03.9 Cellulitis, unspecified
0.691 0.309 0.000
D37.5 Rectum
0.691 0.309 0.000
Z46.8 Fitting and adjustment of other specified devices
0.691 0.309 0.000
W19 Unspecified fall
0.691 0.309 0.000
M77.0 Medial epicondylitis
0.689 0.311 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.688 0.311 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.688 0.312 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.688 0.312 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.688 0.312 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.688 0.312 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.688 0.312 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.688 0.312 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.688 0.312 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.687 0.313 0.000
Z50.2 Alcohol rehabilitation
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.685 0.314 0.000
Z51.9 Medical care, unspecified
0.685 0.315 0.000
Z51.6 Desensitisation to allergens
0.685 0.315 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.684 0.316 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
M10 Gout
0.683 0.317 0.000
S65 Injury of blood vessels at wrist and hand level
0.682 0.318 0.000
Z53.8 Procedure not carried out for other reasons
0.682 0.318 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.682 0.318 0.000
M79.1 Myalgia
0.682 0.318 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.681 0.319 0.000
C67.6 Ureteric orifice
0.681 0.319 0.000
W25 Contact with sharp glass
0.680 0.320 0.000
M81.8 Other osteoporosis
0.679 0.320 0.000
M81.6 Localised osteoporosis [Lequesne]
0.679 0.320 0.000
M81.5 Idiopathic osteoporosis
0.679 0.320 0.000
M81.4 Drug-induced osteoporosis
0.679 0.320 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.679 0.320 0.000
M81.2 Osteoporosis of disuse
0.679 0.320 0.000
M81.1 Postoophorectomy osteoporosis
0.679 0.320 0.000
M81.0 Postmenopausal osteoporosis
0.679 0.320 0.000
M76 Enthesopathies of lower limb, excluding foot
0.679 0.321 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.679 0.321 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.679 0.321 0.000
M34.9 Systemic sclerosis, unspecified
0.678 0.322 0.000
Y42.5 Other oestrogens and progestogens
0.678 0.322 0.000
S80-S89 Injuries to the knee and lower leg
0.676 0.324 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.676 0.324 0.000
C07 Malignant neoplasm of parotid gland
0.675 0.325 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.675 0.325 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.675 0.325 0.000
A41 Other septicaemia
0.675 0.325 0.000
M84.0 Malunion of fracture
0.674 0.326 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.674 0.326 0.000
L57.5 Actinic granuloma
0.674 0.326 0.000
L57.4 Cutis laxa senilis
0.674 0.326 0.000
L57.3 Poikiloderma of Civatte
0.674 0.326 0.000
L57.2 Cutis rhomboidalis nuchae
0.674 0.326 0.000
L57.1 Actinic reticuloid
0.674 0.326 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.673 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.673 0.327 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.327 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.673 0.327 0.000
C01 Malignant neoplasm of base of tongue
0.672 0.328 0.000
Z22.1 Carrier of other intestinal infectious diseases
0.671 0.329 0.000
M21.3 Wrist or foot drop (acquired)
0.671 0.329 0.000
D05.1 Intraductal carcinoma in situ
0.671 0.329 0.000
Y40 Systemic antibiotics
0.670 0.330 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.669 0.330 0.000
M53 Other dorsopathies, not elsewhere classified
0.668 0.332 0.000
M71 Other bursopathies
0.667 0.333 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.667 0.333 0.000
L81 Other disorders of pigmentation
0.666 0.334 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.334 0.000
M51.9 Intervertebral disk disorder, unspecified
0.666 0.334 0.000
M67 Other disorders of synovium and tendon
0.665 0.335 0.000
M07 Psoriatic and enteropathic arthropathies
0.664 0.336 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.664 0.336 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.664 0.336 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.664 0.336 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.664 0.336 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.664 0.336 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.664 0.336 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.664 0.336 0.000
L03.8 Cellulitis of other sites
0.664 0.336 0.000
Z52.3 Bone marrow donor
0.663 0.337 0.000
G54 Nerve root and plexus disorders
0.662 0.338 0.000
C71.2 Temporal lobe
0.662 0.338 0.000
S69 Other and unspecified injuries of wrist and hand
0.662 0.338 0.000
D48.5 Skin
0.662 0.338 0.000
W29 Contact with other powered hand tools and household machinery
0.661 0.339 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.661 0.339 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.661 0.339 0.000
S08 Traumatic amputation of part of head
0.660 0.339 0.000
S07 Crushing injury of head
0.660 0.339 0.000
S04 Injury of cranial nerves
0.660 0.339 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.660 0.339 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
M45 Ankylosing spondylitis
0.660 0.340 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.658 0.342 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.658 0.342 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.658 0.342 0.000
S62.2 Fracture of first metacarpal bone
0.658 0.342 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.657 0.343 0.000
M79.5 Residual foreign body in soft tissue
0.656 0.344 0.000
L04 Acute lymphadenitis
0.656 0.344 0.000
L01 Impetigo
0.656 0.344 0.000
L00 Staphylococcal scalded skin syndrome
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.655 0.345 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.655 0.345 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.655 0.345 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.655 0.345 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.655 0.345 0.000
F70-F79 Mental retardation
0.655 0.345 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.655 0.345 0.000
L65 Other nonscarring hair loss
0.655 0.345 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.655 0.345 0.000
M33 Dermatopolymyositis
0.655 0.345 0.000
M32 Systemic lupus erythematosus
0.655 0.345 0.000
M30 Polyarteritis nodosa and related conditions
0.655 0.345 0.000
G58 Other mononeuropathies
0.654 0.346 0.000
D23.5 Skin of trunk
0.654 0.346 0.000
M50 Cervical disk disorders
0.653 0.347 0.000
Z63.0 Problems in relationship with spouse or partner
0.652 0.347 0.000
D11 Benign neoplasm of major salivary glands
0.652 0.347 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.651 0.349 0.000
Y49.2 Other and unspecified antidepressants
0.651 0.349 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.651 0.349 0.000
M79.9 Soft tissue disorder, unspecified
0.650 0.350 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.650 0.350 0.000
M79.3 Panniculitis, unspecified
0.650 0.350 0.000
M79.2 Neuralgia and neuritis, unspecified
0.650 0.350 0.000
Y42.9 Other and unspecified hormone antagonists
0.649 0.351 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.649 0.351 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.649 0.351 0.000
Y42.4 Oral contraceptives
0.649 0.351 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.649 0.351 0.000
Y42.2 Antithyroid drugs
0.649 0.351 0.000
Y42.1 Thyroid hormones and substitutes
0.649 0.351 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.649 0.351 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.647 0.353 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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