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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80210050
log Bayes Factor = 16.8521
Chromosome 4   position 184,265,904  (GRCh37) Explore rs80210050 on Ensembl!
Variant rs80210050 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
I47 Paroxysmal tachycardia
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.996 0.004 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.994 0.006 0.000
I47.1 Supraventricular tachycardia
0.993 0.007 0.000
I20-I25 Ischaemic heart diseases
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Z60 Problems related to social environment
0.991 0.009 0.000
I25 Chronic ischaemic heart disease
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
Z60.2 Living alone
0.987 0.013 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.981 0.019 0.000
E10 Insulin-dependent diabetes mellitus
0.979 0.021 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.979 0.021 0.000
Z95.0 Presence of cardiac pacemaker
0.978 0.022 0.000
I47.2 Ventricular tachycardia
0.978 0.022 0.000
Z13 Special screening examination for other diseases and disorders
0.976 0.024 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
Z13.9 Special screening examination, unspecified
0.970 0.030 0.000
S00-S09 Injuries to the head
0.970 0.030 0.000
I73 Other peripheral vascular diseases
0.967 0.033 0.000
Chapter X Diseases of the respiratory system
0.965 0.035 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.964 0.036 0.000
Z92 Personal history of medical treatment
0.964 0.036 0.000
E10.9 Without complications
0.961 0.039 0.000
Chapter II Neoplasms
0.956 0.044 0.000
S40-S49 Injuries to the shoulder and upper arm
0.956 0.044 0.000
Chapter VI Diseases of the nervous system
0.950 0.050 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.945 0.055 0.000
J00-J06 Acute upper respiratory infections
0.942 0.058 0.000
E11 Non-insulin-dependent diabetes mellitus
0.941 0.059 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.941 0.059 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.940 0.060 0.000
I73.0 Raynaud's syndrome
0.939 0.061 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.939 0.061 0.000
M05-M14 Inflammatory polyarthropathies
0.937 0.063 0.000
Chapter I Certain infectious and parasitic diseases
0.931 0.069 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.927 0.073 0.000
M13 Other arthritis
0.924 0.076 0.000
S90-S99 Injuries to the ankle and foot
0.920 0.080 0.000
Z04 Examination and observation for other reasons
0.918 0.082 0.000
I25.1 Atherosclerotic heart disease
0.915 0.085 0.000
C60-C63 Malignant neoplasms of male genital organs
0.913 0.087 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.913 0.087 0.000
M13.9 Arthritis, unspecified
0.912 0.088 0.000
I73.9 Peripheral vascular disease, unspecified
0.905 0.095 0.000
B95-B98 Bacterial, viral and other infectious agents
0.902 0.098 0.000
I51 Complications and ill-defined descriptions of heart disease
0.901 0.099 0.000
I50 Heart failure
0.898 0.102 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.897 0.103 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.890 0.110 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.888 0.112 0.000
C61 Malignant neoplasm of prostate
0.885 0.115 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.885 0.115 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.880 0.120 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.873 0.127 0.000
S01 Open wound of head
0.869 0.131 0.000
J06.9 Acute upper respiratory infection, unspecified
0.865 0.135 0.000
I45 Other conduction disorders
0.863 0.137 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.861 0.139 0.000
I46 Cardiac arrest
0.858 0.141 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.858 0.142 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.857 0.143 0.000
I22 Subsequent myocardial infarction
0.855 0.145 0.000
G90-G99 Other disorders of the nervous system
0.855 0.145 0.000
S06 Intracranial injury
0.853 0.147 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.851 0.149 0.000
Chapter XX External causes of morbidity and mortality
0.850 0.150 0.000
I49 Other cardiac arrhythmias
0.849 0.151 0.000
S42 Fracture of shoulder and upper arm
0.846 0.154 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.845 0.155 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.844 0.156 0.000
E11.3 With ophthalmic complications
0.843 0.157 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.842 0.158 0.000
S70-S79 Injuries to the hip and thigh
0.842 0.158 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.841 0.159 0.000
L03 Cellulitis
0.841 0.159 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.838 0.162 0.000
L85 Other epidermal thickening
0.837 0.163 0.000
S09 Other and unspecified injuries of head
0.834 0.166 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.833 0.166 0.000
S92 Fracture of foot, except ankle
0.833 0.167 0.000
Z87 Personal history of other diseases and conditions
0.829 0.171 0.000
J95-J99 Other diseases of the respiratory system
0.828 0.172 0.000
I50.1 Left ventricular failure
0.823 0.177 0.000
Z95.3 Presence of xenogenic heart valve
0.823 0.177 0.000
E00-E07 Disorders of thyroid gland
0.823 0.177 0.000
L20-L30 Dermatitis and eczema
0.823 0.177 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.823 0.177 0.000
Z04.3 Examination and observation following other accident
0.822 0.178 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.822 0.178 0.000
M80-M85 Disorders of bone density and structure
0.820 0.180 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.815 0.185 0.000
G30-G32 Other degenerative diseases of the nervous system
0.814 0.186 0.000
F41 Other anxiety disorders
0.813 0.187 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.813 0.187 0.000
Z95.1 Presence of aortocoronary bypass graft
0.811 0.189 0.000
Z97 Presence of other devices
0.809 0.191 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.809 0.191 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.806 0.194 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.806 0.194 0.000
Z89 Acquired absence of limb
0.805 0.195 0.000
J03 Acute tonsillitis
0.804 0.196 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.804 0.196 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.803 0.197 0.000
Z81 Family history of mental and behavioural disorders
0.800 0.200 0.000
E10.1 With ketoacidosis
0.799 0.201 0.000
A30-A49 Other bacterial diseases
0.798 0.202 0.000
L08 Other local infections of skin and subcutaneous tissue
0.794 0.206 0.000
I05-I09 Chronic rheumatic heart diseases
0.791 0.209 0.000
F60-F69 Disorders of adult personality and behaviour
0.790 0.210 0.000
G93 Other disorders of brain
0.790 0.210 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
Z58 Problems related to physical environment
0.782 0.218 0.000
I24 Other acute ischaemic heart diseases
0.780 0.220 0.000
Z80 Family history of malignant neoplasm
0.780 0.220 0.000
Z98 Other postsurgical states
0.779 0.220 0.000
L82 Seborrhoeic keratosis
0.779 0.221 0.000
E11.5 With peripheral circulatory complications
0.776 0.224 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.776 0.224 0.000
J00 Acute nasopharyngitis [common cold]
0.776 0.224 0.000
I46.0 Cardiac arrest with successful resuscitation
0.775 0.225 0.000
F30-F39 Mood [affective] disorders
0.775 0.225 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.773 0.227 0.000
C44 Other malignant neoplasms of skin
0.773 0.227 0.000
Z92.3 Personal history of irradiation
0.772 0.228 0.000
L40-L45 Papulosquamous disorders
0.772 0.228 0.000
L90 Atrophic disorders of skin
0.770 0.230 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
E11.2 With renal complications
0.767 0.233 0.000
E10.3 With ophthalmic complications
0.766 0.234 0.000
M05 Seropositive rheumatoid arthritis
0.765 0.234 0.000
S01.7 Multiple open wounds of head
0.763 0.236 0.000
Z04.8 Examination and observation for other specified reasons
0.763 0.237 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.763 0.237 0.000
I42 Cardiomyopathy
0.763 0.237 0.000
I51.9 Heart disease, unspecified
0.761 0.239 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.761 0.239 0.000
Z95.4 Presence of other heart-valve replacement
0.761 0.239 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
E20-E35 Disorders of other endocrine glands
0.760 0.240 0.000
D00-D09 In situ neoplasms
0.759 0.241 0.000
S20-S29 Injuries to the thorax
0.758 0.242 0.000
L50-L54 Urticaria and erythema
0.757 0.243 0.000
S91 Open wound of ankle and foot
0.757 0.243 0.000
J60-J70 Lung diseases due to external agents
0.756 0.244 0.000
L85.8 Other specified epidermal thickening
0.756 0.244 0.000
S40 Superficial injury of shoulder and upper arm
0.756 0.244 0.000
L83 Acanthosis nigricans
0.755 0.245 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.754 0.246 0.000
L03.1 Cellulitis of other parts of limb
0.754 0.246 0.000
I78 Diseases of capillaries
0.753 0.247 0.000
I38 Endocarditis, valve unspecified
0.752 0.247 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.751 0.249 0.000
Z63 Other problems related to primary support group, including family circumstances
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
G57 Mononeuropathies of lower limb
0.746 0.254 0.000
E10.4 With neurological complications
0.742 0.257 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.742 0.258 0.000
A80-A89 Viral infections of the central nervous system
0.742 0.258 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.741 0.259 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.741 0.259 0.000
E14 Unspecified diabetes mellitus
0.741 0.259 0.000
Q80-Q89 Other congenital malformations
0.741 0.259 0.000
M11 Other crystal arthropathies
0.740 0.260 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.739 0.261 0.000
J04 Acute laryngitis and tracheitis
0.738 0.261 0.000
I49.0 Ventricular fibrillation and flutter
0.738 0.262 0.000
S09.9 Unspecified injury of head
0.736 0.264 0.000
F41.2 Mixed anxiety and depressive disorder
0.736 0.264 0.000
G93.3 Postviral fatigue syndrome
0.736 0.264 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.735 0.265 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.735 0.265 0.000
M06 Other rheumatoid arthritis
0.734 0.266 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.734 0.266 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.734 0.266 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.733 0.267 0.000
I44 Atrioventricular and left bundle-branch block
0.733 0.267 0.000
I51.4 Myocarditis, unspecified
0.732 0.268 0.000
E04 Other non-toxic goitre
0.732 0.268 0.000
E11.4 With neurological complications
0.732 0.268 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.731 0.269 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.730 0.270 0.000
D37.4 Colon
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.729 0.270 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.727 0.272 0.000
J98 Other respiratory disorders
0.727 0.273 0.000
I49.4 Other and unspecified premature depolarisation
0.727 0.273 0.000
Z57 Occupational exposure to risk-factors
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.726 0.274 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.725 0.275 0.000
I25.2 Old myocardial infarction
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.724 0.276 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.724 0.276 0.000
L30 Other dermatitis
0.723 0.277 0.000
Z80.3 Family history of malignant neoplasm of breast
0.722 0.278 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.721 0.279 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.721 0.279 0.000
I33 Acute and subacute endocarditis
0.721 0.279 0.000
G70-G73 Diseases of myoneural junction and muscle
0.720 0.280 0.000
I35 Nonrheumatic aortic valve disorders
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.719 0.281 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.716 0.283 0.000
I47.0 Reentry ventricular arrhythmia
0.716 0.283 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I45.8 Other specified conduction disorders
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
Z65 Problems related to other psychosocial circumstances
0.714 0.286 0.000
Z64 Problems related to certain psychosocial circumstances
0.714 0.286 0.000
Z62 Other problems related to upbringing
0.714 0.286 0.000
Z61 Problems related to negative life events in childhood
0.714 0.286 0.000
Z59 Problems related to housing and economic circumstances
0.714 0.286 0.000
Z56 Problems related to employment and unemployment
0.714 0.286 0.000
Z55 Problems related to education and literacy
0.714 0.286 0.000
S02 Fracture of skull and facial bones
0.712 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
Z60.9 Problem related to social environment, unspecified
0.710 0.290 0.000
Z60.8 Other problems related to social environment
0.710 0.290 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.710 0.290 0.000
Z60.4 Social exclusion and rejection
0.710 0.290 0.000
Z60.3 Acculturation difficulty
0.710 0.290 0.000
Z60.1 Atypical parenting situation
0.710 0.290 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.710 0.290 0.000
I25.6 Silent myocardial ischaemia
0.710 0.290 0.000
I25.4 Coronary artery aneurysm
0.710 0.290 0.000
I25.3 Aneurysm of heart
0.710 0.290 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.709 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
L04 Acute lymphadenitis
0.707 0.292 0.000
L01 Impetigo
0.707 0.292 0.000
L00 Staphylococcal scalded skin syndrome
0.707 0.292 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
S42.3 Fracture of shaft of humerus
0.706 0.294 0.000
J03.9 Acute tonsillitis, unspecified
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.705 0.295 0.000
L90.5 Scar conditions and fibrosis of skin
0.705 0.295 0.000
M13.0 Polyarthritis, unspecified
0.704 0.296 0.000
M13.98 Arthritis, unspecified (Other)
0.704 0.296 0.000
S92.0 Fracture of calcaneus
0.704 0.296 0.000
Z10 Routine general health check-up of defined subpopulation
0.703 0.296 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.703 0.297 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
S70 Superficial injury of hip and thigh
0.703 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.703 0.297 0.000
Z12 Special screening examination for neoplasms
0.702 0.298 0.000
E10.8 With unspecified complications
0.702 0.298 0.000
E10.7 With multiple complications
0.702 0.298 0.000
E10.6 With other specified complications
0.702 0.298 0.000
E10.5 With peripheral circulatory complications
0.702 0.298 0.000
E10.2 With renal complications
0.702 0.298 0.000
E10.0 With coma
0.702 0.298 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.702 0.298 0.000
L89 Decubitus ulcer
0.700 0.300 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.700 0.300 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
Z13.5 Special screening examination for eye and ear disorders
0.700 0.300 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.700 0.300 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.700 0.300 0.000
Z13.2 Special screening examination for nutritional disorders
0.700 0.300 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.699 0.301 0.000
I72 Other aneurysm
0.699 0.301 0.000
Z04.1 Examination and observation following transport accident
0.699 0.301 0.000
D37.5 Rectum
0.698 0.302 0.000
M91-M94 Chondropathies
0.698 0.302 0.000
S00 Superficial injury of head
0.698 0.302 0.000
Z92.8 Personal history of other medical treatment
0.698 0.302 0.000
S01.9 Open wound of head, part unspecified
0.697 0.303 0.000
Q60-Q64 Congenital malformations of the urinary system
0.696 0.303 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.304 0.000
Z13.1 Special screening examination for diabetes mellitus
0.695 0.305 0.000
S08 Traumatic amputation of part of head
0.695 0.305 0.000
S07 Crushing injury of head
0.695 0.305 0.000
S05 Injury of eye and orbit
0.695 0.305 0.000
S04 Injury of cranial nerves
0.695 0.305 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.694 0.306 0.000
I71 Aortic aneurysm and dissection
0.694 0.306 0.000
I73.8 Other specified peripheral vascular diseases
0.693 0.307 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.693 0.307 0.000
G51 Facial nerve disorders
0.692 0.308 0.000
I30 Acute pericarditis
0.692 0.308 0.000
M81 Osteoporosis without pathological fracture
0.692 0.308 0.000
S42.2 Fracture of upper end of humerus
0.691 0.309 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.691 0.309 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.691 0.309 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.691 0.309 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.691 0.309 0.000
Z92.9 Personal history of medical treatment, unspecified
0.691 0.309 0.000
Z92.5 Personal history of rehabilitation measures
0.691 0.309 0.000
Z92.0 Personal history of contraception
0.691 0.309 0.000
I45.6 Preexcitation syndrome
0.691 0.309 0.000
S01.2 Open wound of nose
0.690 0.310 0.000
L05 Pilonidal cyst
0.689 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.689 0.311 0.000
I49.3 Ventricular premature depolarisation
0.688 0.312 0.000
Z97.4 Presence of external hearing-aid
0.687 0.313 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.686 0.314 0.000
S48 Traumatic amputation of shoulder and upper arm
0.686 0.314 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.686 0.314 0.000
S44 Injury of nerves at shoulder and upper arm level
0.686 0.314 0.000
S41 Open wound of shoulder and upper arm
0.686 0.314 0.000
S47 Crushing injury of shoulder and upper arm
0.686 0.314 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
F00 Dementia in Alzheimer's disease
0.685 0.314 0.000
Q23 Congenital malformations of aortic and mitral valves
0.685 0.315 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.684 0.316 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
G30 Alzheimer's disease
0.682 0.317 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.682 0.318 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.681 0.319 0.000
I51.7 Cardiomegaly
0.681 0.319 0.000
Z83 Family history of other specific disorders
0.681 0.319 0.000
Q21 Congenital malformations of cardiac septa
0.681 0.319 0.000
S32 Fracture of lumbar spine and pelvis
0.681 0.319 0.000
Q00-Q07 Congenital malformations of the nervous system
0.679 0.321 0.000
F41.9 Anxiety disorder, unspecified
0.679 0.321 0.000
S01.5 Open wound of lip and oral cavity
0.679 0.321 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.679 0.321 0.000
G58 Other mononeuropathies
0.678 0.322 0.000
M20-M25 Other joint disorders
0.678 0.322 0.000
Z98.8 Other specified postsurgical states
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
E50-E64 Other nutritional deficiencies
0.677 0.323 0.000
C44.2 Skin of ear and external auricular canal
0.676 0.324 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.676 0.324 0.000
I50.0 Congestive heart failure
0.676 0.324 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.675 0.325 0.000
J01 Acute sinusitis
0.675 0.325 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
E11.7 With multiple complications
0.675 0.325 0.000
E11.6 With other specified complications
0.675 0.325 0.000
E11.1 With ketoacidosis
0.675 0.325 0.000
E11.0 With coma
0.675 0.325 0.000
Z04.9 Examination and observation for unspecified reason
0.675 0.325 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.674 0.325 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.674 0.325 0.000
L94 Other localised connective tissue disorders
0.674 0.325 0.000
L93 Lupus erythematosus
0.674 0.325 0.000
L87 Transepidermal elimination disorders
0.674 0.325 0.000
L88 Pyoderma gangrenosum
0.674 0.325 0.000
L86 Keratoderma in diseases classified elsewhere
0.674 0.325 0.000
L80 Vitiligo
0.674 0.325 0.000
L03.9 Cellulitis, unspecified
0.674 0.326 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.674 0.326 0.000
Q35-Q37 Cleft lip and cleft palate
0.674 0.326 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.674 0.326 0.000
J40-J47 Chronic lower respiratory diseases
0.673 0.327 0.000
I51.8 Other ill-defined heart diseases
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
M12 Other specific arthropathies
0.672 0.328 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.672 0.328 0.000
M08 Juvenile arthritis
0.672 0.328 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.672 0.328 0.000
G96 Other disorders of central nervous system
0.671 0.328 0.000
E07 Other disorders of thyroid
0.671 0.329 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.671 0.329 0.000
Z89.4 Acquired absence of foot and ankle
0.670 0.330 0.000
S92.3 Fracture of metatarsal bone
0.669 0.331 0.000
F43 Reaction to severe stress, and adjustment disorders
0.669 0.331 0.000
S06.4 Epidural haemorrhage
0.668 0.332 0.000
L40 Psoriasis
0.668 0.332 0.000
L57.0 Actinic keratosis
0.668 0.332 0.000
B99-B99 Other infectious diseases
0.667 0.333 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.667 0.333 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.667 0.333 0.000
B65-B83 Helminthiases
0.667 0.333 0.000
B50-B64 Protozoal diseases
0.667 0.333 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.667 0.333 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.667 0.333 0.000
A75-A79 Rickettsioses
0.667 0.333 0.000
A70-A74 Other diseases caused by chlamydiae
0.667 0.333 0.000
A65-A69 Other spirochaetal diseases
0.667 0.333 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.667 0.333 0.000
A20-A28 Certain zoonotic bacterial diseases
0.667 0.333 0.000
A15-A19 Tuberculosis
0.667 0.333 0.000
F42 Obsessive-compulsive disorder
0.667 0.333 0.000
S92.2 Fracture of other tarsal bone(s)
0.667 0.333 0.000
Chapter VIII Diseases of the ear and mastoid process
0.666 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.665 0.335 0.000
S42.0 Fracture of clavicle
0.665 0.335 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.665 0.335 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.665 0.335 0.000
M80 Osteoporosis with pathological fracture
0.664 0.336 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.664 0.336 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.664 0.336 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.664 0.336 0.000
I45.5 Other specified heart block
0.663 0.336 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.663 0.337 0.000
F03 Unspecified dementia
0.662 0.337 0.000
M13.8 Other specified arthritis
0.662 0.338 0.000
M13.1 Monoarthritis, not elsewhere classified
0.662 0.338 0.000
W29 Contact with other powered hand tools and household machinery
0.662 0.338 0.000
T79-T79 Certain early complications of trauma
0.662 0.338 0.000
G90 Disorders of autonomic nervous system
0.661 0.339 0.000
S99 Other and unspecified injuries of ankle and foot
0.660 0.340 0.000
S98 Traumatic amputation of ankle and foot
0.660 0.340 0.000
S97 Crushing injury of ankle and foot
0.660 0.340 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.660 0.340 0.000
S95 Injury of blood vessels at ankle and foot level
0.660 0.340 0.000
S94 Injury of nerves at ankle and foot level
0.660 0.340 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.660 0.340 0.000
S90 Superficial injury of ankle and foot
0.660 0.340 0.000
S06.2 Diffuse brain injury
0.660 0.340 0.000
S43.0 Dislocation of shoulder joint
0.659 0.341 0.000
S43.1 Dislocation of acromioclavicular joint
0.658 0.342 0.000
Z04.6 General psychiatric examination, requested by authority
0.658 0.342 0.000
Z04.5 Examination and observation following other inflicted injury
0.658 0.342 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.658 0.342 0.000
Z04.2 Examination and observation following work accident
0.658 0.342 0.000
Z04.0 Blood-alcohol and blood-drug test
0.658 0.342 0.000
F17.1 Harmful use
0.657 0.343 0.000
I70 Atherosclerosis
0.657 0.343 0.000
Z81.8 Family history of other mental and behavioural disorders
0.656 0.343 0.000
Z87.0 Personal history of diseases of the respiratory system
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.655 0.344 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.655 0.345 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.655 0.345 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.654 0.346 0.000
C60 Malignant neoplasm of penis
0.654 0.346 0.000
M13.93 Arthritis, unspecified (Forearm)
0.654 0.346 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.654 0.346 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.654 0.346 0.000
G57.6 Lesion of plantar nerve
0.653 0.347 0.000
S06.8 Other intracranial injuries
0.653 0.347 0.000
F33 Recurrent depressive disorder
0.653 0.347 0.000
C64-C68 Malignant neoplasms of urinary tract
0.652 0.348 0.000
S72 Fracture of femur
0.652 0.348 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.348 0.000
J30-J39 Other diseases of upper respiratory tract
0.652 0.348 0.000
F60 Specific personality disorders
0.650 0.350 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.650 0.350 0.000
L84 Corns and callosities
0.650 0.350 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.650 0.350 0.000
E11.9 Without complications
0.648 0.352 0.000
S60-S69 Injuries to the wrist and hand
0.647 0.352 0.000
M13.94 Arthritis, unspecified (Hand)
0.647 0.353 0.000
I42.0 Dilated cardiomyopathy
0.647 0.353 0.000
S01.4 Open wound of cheek and temporomandibular area
0.646 0.354 0.000
I51.6 Cardiovascular disease, unspecified
0.646 0.354 0.000
I51.5 Myocardial degeneration
0.646 0.354 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.646 0.354 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.646 0.354 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.646 0.354 0.000
I51.0 Cardiac septal defect, acquired
0.646 0.354 0.000
A41 Other septicaemia
0.646 0.354 0.000
C44.1 Skin of eyelid, including canthus
0.644 0.356 0.000
I08 Multiple valve diseases
0.644 0.356 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.644 0.356 0.000
A46 Erysipelas
0.644 0.356 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.643 0.357 0.000
J06.0 Acute laryngopharyngitis
0.643 0.357 0.000
J98.1 Pulmonary collapse
0.643 0.357 0.000
E06 Thyroiditis
0.643 0.357 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.643 0.357 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.642 0.357 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.642 0.358 0.000
Z94 Transplanted organ and tissue status
0.641 0.359 0.000
S91.3 Open wound of other parts of foot
0.640 0.360 0.000
A40 Streptococcal septicaemia
0.640 0.360 0.000
J81 Pulmonary oedema
0.639 0.361 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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