TreeWAS – Variant ID: rs9468831

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
Chapter V Mental and behavioural disorders	0.999	0.001
D37-D48 Neoplasms of uncertain or unknown behaviour	0.996	0.004
Z88.0 Personal history of allergy to penicillin	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
F40-F48 Neurotic, stress-related and somatoform disorders	0.993	0.007
E20-E35 Disorders of other endocrine glands	0.993	0.007
C43-C44 Melanoma and other malignant neoplasms of skin	0.986	0.014
Chapter XIV Diseases of the genitourinary system	0.985	0.015
M70-M79 Other soft tissue disorders	0.985	0.015
F41 Other anxiety disorders	0.982	0.018
F41.2 Mixed anxiety and depressive disorder	0.979	0.021
S60-S69 Injuries to the wrist and hand	0.969	0.031
M75 Shoulder lesions	0.969	0.031
C44 Other malignant neoplasms of skin	0.968	0.032
N20-N23 Urolithiasis	0.966	0.034
C15-C26 Malignant neoplasms of digestive organs	0.966	0.034
E70-E90 Metabolic disorders	0.962	0.038
M05-M14 Inflammatory polyarthropathies	0.959	0.041
M20-M25 Other joint disorders	0.955	0.045
C44.3 Skin of other and unspecified parts of face	0.955	0.045
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.955	0.045
D00-D09 In situ neoplasms	0.952	0.048
F00-F09 Organic, including symptomatic, mental disorders	0.948	0.052
M75.1 Rotator cuff syndrome	0.937	0.063
F30-F39 Mood [affective] disorders	0.936	0.064
M13 Other arthritis	0.935	0.065
E23 Hypofunction and other disorders of pituitary gland	0.934	0.066
Chapter XX External causes of morbidity and mortality	0.925	0.075
M24 Other specific joint derangements	0.925	0.075
N20 Calculus of kidney and ureter	0.924	0.076
E00-E07 Disorders of thyroid gland	0.923	0.077
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.914	0.086
M13.9 Arthritis, unspecified	0.913	0.087
M65-M68 Disorders of synovium and tendon	0.912	0.088
M25 Other joint disorders, not elsewhere classified	0.912	0.088
N17-N19 Renal failure	0.912	0.088
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.909	0.091
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.901	0.099
N10-N16 Renal tubulo-interstitial diseases	0.900	0.100
S61 Open wound of wrist and hand	0.896	0.104
M80-M85 Disorders of bone density and structure	0.890	0.110
Chapter VI Diseases of the nervous system	0.889	0.111
C21 Malignant neoplasm of anus and anal canal	0.889	0.111
M13.96 Arthritis, unspecified (Lower leg)	0.888	0.112
F33 Recurrent depressive disorder	0.887	0.113
E23.0 Hypopituitarism	0.881	0.119
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.881	0.119
C44.1 Skin of eyelid, including canthus	0.879	0.121
S40-S49 Injuries to the shoulder and upper arm	0.877	0.123
E29 Testicular dysfunction	0.877	0.123
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.874	0.126
N23 Unspecified renal colic	0.874	0.126
M75.4 Impingement syndrome of shoulder	0.872	0.128
E86 Volume depletion	0.872	0.128
E03 Other hypothyroidism	0.871	0.129
S50-S59 Injuries to the elbow and forearm	0.870	0.130
D48.5 Skin	0.869	0.131
D04 Carcinoma in situ of skin	0.868	0.132
N19 Unspecified renal failure	0.867	0.133
M75.0 Adhesive capsulitis of shoulder	0.864	0.136
S61.0 Open wound of finger(s) without damage to nail	0.860	0.140
S00-S09 Injuries to the head	0.854	0.146
S70-S79 Injuries to the hip and thigh	0.853	0.147
N80-N98 Noninflammatory disorders of female genital tract	0.853	0.147
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.852	0.148
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.852	0.148
F40 Phobic anxiety disorders	0.851	0.149
C44.4 Skin of scalp and neck	0.850	0.150
S66 Injury of muscle and tendon at wrist and hand level	0.849	0.151
D48.1 Connective and other soft tissue	0.846	0.154
F33.9 Recurrent depressive disorder, unspecified	0.844	0.156
C43 Malignant melanoma of skin	0.840	0.160
C20 Malignant neoplasm of rectum	0.839	0.161
F43 Reaction to severe stress, and adjustment disorders	0.837	0.163
E27 Other disorders of adrenal gland	0.837	0.163
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.836	0.164
N20.1 Calculus of ureter	0.836	0.164
G90-G99 Other disorders of the nervous system	0.835	0.165
C71 Malignant neoplasm of brain	0.835	0.165
D03 Melanoma in situ	0.834	0.166
M45-M49 Spondylopathies	0.832	0.168
F03 Unspecified dementia	0.830	0.170
M24.2 Disorder of ligament	0.830	0.170
D45 Polycythaemia vera	0.827	0.173
N94.6 Dysmenorrhoea, unspecified	0.827	0.173
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.826	0.174
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.821	0.179
C18 Malignant neoplasm of colon	0.820	0.180
E03.9 Hypothyroidism, unspecified	0.818	0.182
M13.94 Arthritis, unspecified (Hand)	0.817	0.183
G99 Other disorders of nervous system in diseases classified elsewhere	0.813	0.187
E87 Other disorders of fluid, electrolyte and acid-base balance	0.813	0.187
E50-E64 Other nutritional deficiencies	0.810	0.189
S42 Fracture of shoulder and upper arm	0.810	0.190
M70 Soft tissue disorders related to use, overuse and pressure	0.809	0.190
M24.8 Other specific joint derangements, not elsewhere classified	0.808	0.192
E05 Thyrotoxicosis [hyperthyroidism]	0.808	0.192
S06 Intracranial injury	0.807	0.193
C19 Malignant neoplasm of rectosigmoid junction	0.807	0.193
D06 Carcinoma in situ of cervix uteri	0.807	0.193
S90-S99 Injuries to the ankle and foot	0.807	0.193
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.804	0.196
S64 Injury of nerves at wrist and hand level	0.802	0.198
G99.2 Myelopathy in diseases classified elsewhere	0.799	0.201
M24.5 Contracture of joint	0.798	0.202
D41.4 Bladder	0.797	0.203
D04.7 Skin of lower limb, including hip	0.797	0.203
E29.1 Testicular hypofunction	0.793	0.207
M25.4 Effusion of joint	0.791	0.209
T66-T78 Other and unspecified effects of external causes	0.790	0.210
S10-S19 Injuries to the neck	0.790	0.210
N20.0 Calculus of kidney	0.789	0.211
M65 Synovitis and tenosynovitis	0.787	0.212
E40-E46 Malnutrition	0.787	0.213
N10 Acute tubulo-interstitial nephritis	0.787	0.213
F31 Bipolar affective disorder	0.786	0.214
M21 Other acquired deformities of limbs	0.786	0.214
G20-G26 Extrapyramidal and movement disorders	0.785	0.215
M25.8 Other specified joint disorders	0.785	0.215
S20-S29 Injuries to the thorax	0.784	0.216
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.784	0.216
F05 Delirium, not induced by alcohol and other psychoactive substances	0.783	0.217
C21.1 Anal canal	0.783	0.217
N60-N64 Disorders of breast	0.782	0.218
T79-T79 Certain early complications of trauma	0.782	0.218
E89.0 Postprocedural hypothyroidism	0.782	0.218
C09 Malignant neoplasm of tonsil	0.782	0.218
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.778	0.222
E20 Hypoparathyroidism	0.778	0.222
M33 Dermatopolymyositis	0.777	0.223
W20-W49 Exposure to inanimate mechanical forces	0.777	0.223
M76 Enthesopathies of lower limb, excluding foot	0.777	0.223
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.774	0.226
N17 Acute renal failure	0.774	0.226
X20-X29 Contact with venomous animals and plants	0.773	0.227
M75.2 Bicipital tendinitis	0.772	0.228
M85 Other disorders of bone density and structure	0.772	0.228
C43.7 Malignant melanoma of lower limb, including hip	0.771	0.229
N97 Female infertility	0.771	0.229
E74 Other disorders of carbohydrate metabolism	0.769	0.231
M13.98 Arthritis, unspecified (Other)	0.768	0.232
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.768	0.232
M15-M19 Arthrosis	0.767	0.233
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.766	0.234
D47.3 Essential (haemorrhagic) thrombocythaemia	0.764	0.236
D41.0 Kidney	0.763	0.237
M77 Other enthesopathies	0.763	0.237
F42 Obsessive-compulsive disorder	0.763	0.237
M25.3 Other instability of joint	0.762	0.238
T36-T50 Poisoning by drugs, medicaments and biological substances	0.761	0.239
E87.5 Hyperkalaemia	0.761	0.239
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.758	0.241
S70 Superficial injury of hip and thigh	0.758	0.242
M67 Other disorders of synovium and tendon	0.758	0.242
M48 Other spondylopathies	0.757	0.243
C21.0 Anus, unspecified	0.757	0.243
C25 Malignant neoplasm of pancreas	0.756	0.244
M40-M43 Deforming dorsopathies	0.755	0.245
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.754	0.246
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.753	0.246
M91-M94 Chondropathies	0.753	0.247
W00-W19 Falls	0.753	0.247
F80-F89 Disorders of psychological development	0.753	0.247
E83 Disorders of mineral metabolism	0.752	0.248
M25.6 Stiffness of joint, not elsewhere classified	0.751	0.249
M60-M63 Disorders of muscles	0.750	0.250
M19 Other arthrosis	0.750	0.250
F40.2 Specific (isolated) phobias	0.749	0.251
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.748	0.252
G20 Parkinson's disease	0.748	0.252
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.748	0.252
E34 Other endocrine disorders	0.746	0.254
S61.9 Open wound of wrist and hand, part unspecified	0.746	0.254
C44.9 Malignant neoplasm of skin, unspecified	0.744	0.256
C71.1 Frontal lobe	0.743	0.257
S67 Crushing injury of wrist and hand	0.742	0.258
E88 Other metabolic disorders	0.741	0.259
M14 Arthropathies in other diseases classified elsewhere	0.741	0.259
C26 Malignant neoplasm of other and ill-defined digestive organs	0.740	0.260
M00-M03 Infectious arthropathies	0.740	0.260
E22 Hyperfunction of pituitary gland	0.739	0.261
M05 Seropositive rheumatoid arthritis	0.738	0.262
C01 Malignant neoplasm of base of tongue	0.737	0.263
F00 Dementia in Alzheimer's disease	0.736	0.264
M82 Osteoporosis in diseases classified elsewhere	0.735	0.265
M84 Disorders of continuity of bone	0.734	0.266
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.734	0.266
S42.3 Fracture of shaft of humerus	0.733	0.267
M86-M90 Other osteopathies	0.732	0.268
D04.3 Skin of other and unspecified parts of face	0.731	0.268
E06 Thyroiditis	0.731	0.269
M13.0 Polyarthritis, unspecified	0.730	0.270
M65.9 Synovitis and tenosynovitis, unspecified	0.729	0.271
E26 Hyperaldosteronism	0.729	0.271
E28 Ovarian dysfunction	0.729	0.271
N20.2 Calculus of kidney with calculus of ureter	0.729	0.271
Chapter XXII Codes for special purposes	0.728	0.272
N25-N29 Other disorders of kidney and ureter	0.727	0.273
E23.2 Diabetes insipidus	0.723	0.276
D09 Carcinoma in situ of other and unspecified sites	0.723	0.277
S02 Fracture of skull and facial bones	0.722	0.278
X60-X84 Intentional self-harm	0.721	0.279
E73 Lactose intolerance	0.720	0.280
N85 Other noninflammatory disorders of uterus, except cervix	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.283
F70-F79 Mental retardation	0.716	0.283
M71 Other bursopathies	0.716	0.284
C69 Malignant neoplasm of eye and adnexa	0.716	0.284
S56 Injury of muscle and tendon at forearm level	0.716	0.284
N89 Other noninflammatory disorders of vagina	0.715	0.285
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.714	0.285
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.714	0.285
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.714	0.285
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.714	0.286
D48.7 Other specified sites	0.714	0.286
D48.0 Bone and articular cartilage	0.713	0.287
G50-G59 Nerve, nerve root and plexus disorders	0.713	0.287
F48 Other neurotic disorders	0.712	0.288
F44 Dissociative [conversion] disorders	0.712	0.288
E35 Disorders of endocrine glands in diseases classified elsewhere	0.712	0.288
E32 Diseases of thymus	0.712	0.288
E31 Polyglandular dysfunction	0.712	0.288
E30 Disorders of puberty, not elsewhere classified	0.712	0.288
E25 Adrenogenital disorders	0.712	0.288
E24 Cushing's syndrome	0.712	0.288
F41.1 Generalised anxiety disorder	0.711	0.289
E05.9 Thyrotoxicosis, unspecified	0.711	0.289
V80-V89 Other land transport accidents	0.711	0.289
C18.5 Splenic flexure	0.709	0.291
E65-E68 Obesity and other hyperalimentation	0.708	0.291
M19.0 Primary arthrosis of other joints	0.707	0.293
M73 Soft tissue disorders in diseases classified elsewhere	0.706	0.294
F41.8 Other specified anxiety disorders	0.704	0.296
F41.3 Other mixed anxiety disorders	0.704	0.296
Y52 Agents primarily affecting the cardiovascular system	0.704	0.296
D06.9 Cervix, unspecified	0.703	0.297
F01 Vascular dementia	0.703	0.297
M48.0 Spinal stenosis	0.703	0.297
C18.7 Sigmoid colon	0.703	0.297
S68 Traumatic amputation of wrist and hand	0.700	0.300
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.700	0.300
D03.5 Melanoma in situ of trunk	0.700	0.300
M19.9 Arthrosis, unspecified	0.699	0.301
N21 Calculus of lower urinary tract	0.699	0.301
N94.0 Mittelschmerz	0.698	0.302
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302
S06.5 Traumatic subdural haemorrhage	0.698	0.302
M24.26 Disorder of ligament (Lower leg)	0.698	0.302
Y42.0 Glucocorticoids and synthetic analogs	0.697	0.303
M66 Spontaneous rupture of synovium and tendon	0.696	0.304
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.696	0.304
C09.9 Tonsil, unspecified	0.696	0.304
S65 Injury of blood vessels at wrist and hand level	0.695	0.305
M75.8 Other shoulder lesions	0.695	0.305
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.695	0.305
C44.8 Overlapping lesion of skin	0.694	0.306
N20.9 Urinary calculus, unspecified	0.694	0.306
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.694	0.306
F99-F99 Unspecified mental disorder	0.693	0.307
M10 Gout	0.693	0.307
N22 Calculus of urinary tract in diseases classified elsewhere	0.692	0.307
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.692	0.308
C17 Malignant neoplasm of small intestine	0.692	0.308
C23 Malignant neoplasm of gallbladder	0.692	0.308
Y60-Y69 Misadventures to patients during surgical and medical care	0.691	0.309
N97.9 Female infertility, unspecified	0.691	0.309
M11 Other crystal arthropathies	0.690	0.310
S70.9 Superficial injury of hip and thigh, unspecified	0.690	0.310
E85 Amyloidosis	0.690	0.310
E84 Cystic fibrosis	0.690	0.310
E79 Disorders of purine and pyrimidine metabolism	0.690	0.310
E77 Disorders of glycoprotein metabolism	0.690	0.310
E76 Disorders of glycosaminoglycan metabolism	0.690	0.310
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.690	0.310
E72 Other disorders of amino-acid metabolism	0.690	0.310
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.690	0.310
E70 Disorders of aromatic amino-acid metabolism	0.690	0.310
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.690	0.310
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.689	0.311
F33.1 Recurrent depressive disorder, current episode moderate	0.688	0.312
Y49 Psychotropic drugs, not elsewhere classified	0.688	0.312
M12 Other specific arthropathies	0.687	0.312
M09 Juvenile arthritis in diseases classified elsewhere	0.687	0.312
M08 Juvenile arthritis	0.687	0.312
Y57 Other and unspecified drugs and medicaments	0.687	0.312
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.686	0.314
M70.6 Trochanteric bursitis	0.686	0.314
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.685	0.315
M32 Systemic lupus erythematosus	0.685	0.315
M30 Polyarteritis nodosa and related conditions	0.685	0.315
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.685	0.315
D48.4 Peritoneum	0.685	0.315
D48.3 Retroperitoneum	0.685	0.315
D48.2 Peripheral nerves and autonomic nervous system	0.685	0.315
S52 Fracture of forearm	0.684	0.316
S06.2 Diffuse brain injury	0.684	0.316
D02 Carcinoma in situ of middle ear and respiratory system	0.682	0.318
D01 Carcinoma in situ of other and unspecified digestive organs	0.682	0.318
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.682	0.318
F60-F69 Disorders of adult personality and behaviour	0.681	0.319
M24.0 Loose body in joint	0.681	0.319
M07 Psoriatic and enteropathic arthropathies	0.680	0.320
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.680	0.320
F02 Dementia in other diseases classified elsewhere	0.680	0.320
F09 Unspecified organic or symptomatic mental disorder	0.680	0.320
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.680	0.320
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
M24.51 Contracture of joint (Shoulder region)	0.679	0.321
C18.4 Transverse colon	0.679	0.321
N64 Other disorders of breast	0.679	0.321
M13.91 Arthritis, unspecified (Shoulder region)	0.679	0.321
S20 Superficial injury of thorax	0.678	0.322
N11 Chronic tubulo-interstitial nephritis	0.677	0.323
S42.30 Fracture of shaft of humerus (closed)	0.677	0.323
M85.8 Other specified disorders of bone density and structure	0.676	0.324
N17.9 Acute renal failure, unspecified	0.675	0.325
Y40 Systemic antibiotics	0.673	0.327
E89.2 Postprocedural hypoparathyroidism	0.673	0.327
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.672	0.328
N92 Excessive, frequent and irregular menstruation	0.672	0.328
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.672	0.328
F43.1 Posttraumatic stress disorder	0.672	0.328
C44.0 Skin of lip	0.672	0.328
S90 Superficial injury of ankle and foot	0.672	0.328
F38 Other mood [affective] disorders	0.671	0.329
F34 Persistent mood [affective] disorders	0.671	0.329
F30 Manic episode	0.671	0.329
F39 Unspecified mood [affective] disorder	0.671	0.329
M24.27 Disorder of ligament (Ankle and foot)	0.671	0.329
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.670	0.329
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.670	0.330
M13.8 Other specified arthritis	0.670	0.330
M13.1 Monoarthritis, not elsewhere classified	0.670	0.330
E23.7 Disorder of pituitary gland, unspecified	0.670	0.330
E23.6 Other disorders of pituitary gland	0.670	0.330
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.670	0.330
E23.1 Drug-induced hypopituitarism	0.670	0.330
D43.0 Brain, supratentorial	0.669	0.330
S50 Superficial injury of forearm	0.669	0.331
E21.0 Primary hyperparathyroidism	0.669	0.331
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.669	0.331
D48.6 Breast	0.668	0.332
C02 Malignant neoplasm of other and unspecified parts of tongue	0.667	0.332
E27.8 Other specified disorders of adrenal gland	0.667	0.333
S66.8 Injury of other muscles and tendons at wrist and hand level	0.666	0.334
Y42.7 Androgens and anabolic congeners	0.666	0.334
F05.9 Delirium, unspecified	0.665	0.334
E89.3 Postprocedural hypopituitarism	0.664	0.336
X23 Contact with hornets, wasps and bees	0.664	0.336
Y35-Y36 Legal intervention and operations of war	0.663	0.336
Y10-Y34 Event of undetermined intent	0.663	0.336
Y00-Y09 Assault	0.663	0.336
X85-X99 Assault	0.663	0.336
X30-X39 Exposure to forces of nature	0.663	0.336
X10-X19 Contact with heat and hot substances	0.663	0.336
X00-X09 Exposure to smoke, fire and flames	0.663	0.336
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.663	0.336
W75-W84 Other accidental threats to breathing	0.663	0.336
W65-W74 Accidental drowning and submersion	0.663	0.336
W50-W64 Exposure to animate mechanical forces	0.663	0.336
V98-V99 Other and unspecified transport accidents	0.663	0.336
V95-V97 Air and space transport accidents	0.663	0.336
V90-V94 Water transport accidents	0.663	0.336
V70-V79 Bus occupant injured in transport accident	0.663	0.336
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.663	0.336
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.663	0.336
V40-V49 Car occupant injured in transport accident	0.663	0.336
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.663	0.336
V01-V09 Pedestrian injured in transport accident	0.663	0.336
E61 Deficiency of other nutrient elements	0.663	0.337
M24.9 Joint derangement, unspecified	0.663	0.337
M24.7 Protrusio acetabuli	0.663	0.337
M24.6 Ankylosis of joint	0.663	0.337
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.663	0.337
M13.97 Arthritis, unspecified (Ankle and foot)	0.663	0.337
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.662	0.338
E00 Congenital iodine-deficiency syndrome	0.662	0.338
E02 Subclinical iodine-deficiency hypothyroidism	0.662	0.338
S60 Superficial injury of wrist and hand	0.661	0.338
S71 Open wound of hip and thigh	0.661	0.338
M13.93 Arthritis, unspecified (Forearm)	0.661	0.339
M25.46 Effusion of joint (Lower leg)	0.661	0.339
E83.5 Disorders of calcium metabolism	0.661	0.339
C71.3 Parietal lobe	0.660	0.340
D46 Myelodysplastic syndromes	0.660	0.340
X50-X57 Overexertion, travel and privation	0.660	0.340
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.659	0.341
C44.6 Skin of upper limb, including shoulder	0.659	0.341
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.659	0.341
D80-D89 Certain disorders involving the immune mechanism	0.659	0.341
Chapter VII Diseases of the eye and adnexa	0.657	0.343
G00-G09 Inflammatory diseases of the central nervous system	0.657	0.343
E87.6 Hypokalaemia	0.657	0.343
H53 Visual disturbances	0.656	0.344
S64.0 Injury of ulnar nerve at wrist and hand level	0.656	0.344
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.656	0.344
C70 Malignant neoplasm of meninges	0.656	0.344
M13.92 Arthritis, unspecified (Upper arm)	0.654	0.346
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.654	0.346
M25.2 Flail joint	0.654	0.346
M25.1 Fistula of joint	0.654	0.346
M25.0 Haemarthrosis	0.654	0.346
S69 Other and unspecified injuries of wrist and hand	0.653	0.347
D03.4 Melanoma in situ of scalp and neck	0.653	0.347
H53-H54 Visual disturbances and blindness	0.653	0.347
D41.9 Urinary organ, unspecified	0.651	0.348
D41.7 Other urinary organs	0.651	0.348
D41.3 Urethra	0.651	0.348
D41.2 Ureter	0.651	0.348
D41.1 Renal pelvis	0.651	0.348
Chapter IX Diseases of the circulatory system	0.652	0.348
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.651	0.349
M24.23 Disorder of ligament (Forearm)	0.651	0.349
Chapter X Diseases of the respiratory system	0.651	0.349
G90 Disorders of autonomic nervous system	0.651	0.349
M24.4 Recurrent dislocation and subluxation of joint	0.650	0.350
M25.45 Effusion of joint (Pelvic region and thigh)	0.650	0.350
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.649	0.351
M25.83 Other specified joint disorders (Forearm)	0.649	0.351
S06.0 Concussion	0.649	0.351
M33.1 Other dermatomyositis	0.649	0.351
M25.9 Joint disorder, unspecified	0.647	0.352
T78 Adverse effects, not elsewhere classified	0.647	0.353
M72 Fibroblastic disorders	0.647	0.353
F43.2 Adjustment disorders	0.647	0.353
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.646	0.354
C13 Malignant neoplasm of hypopharynx	0.646	0.354
C11 Malignant neoplasm of nasopharynx	0.646	0.354
C10 Malignant neoplasm of oropharynx	0.646	0.354
C08 Malignant neoplasm of other and unspecified major salivary glands	0.646	0.354
C06 Malignant neoplasm of other and unspecified parts of mouth	0.646	0.354
C05 Malignant neoplasm of palate	0.646	0.354
C04 Malignant neoplasm of floor of mouth	0.646	0.354
C03 Malignant neoplasm of gum	0.646	0.354
C00 Malignant neoplasm of lip	0.646	0.354
C12 Malignant neoplasm of pyriform sinus	0.646	0.354
C07 Malignant neoplasm of parotid gland	0.646	0.354
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.645	0.354
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.645	0.355
N15 Other renal tubulo-interstitial diseases	0.645	0.355
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.645	0.355
D43.2 Brain, unspecified	0.645	0.355
M21.2 Flexion deformity	0.644	0.356
S52.0 Fracture of upper end of ulna	0.644	0.356
E27.9 Disorder of adrenal gland, unspecified	0.644	0.356
C18.3 Hepatic flexure	0.642	0.357
W10 Fall on and from stairs and steps	0.642	0.358
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.642	0.358
E27.4 Other and unspecified adrenocortical insufficiency	0.641	0.359
N62 Hypertrophy of breast	0.641	0.359
S62 Fracture at wrist and hand level	0.641	0.359
N99-N99 Other disorders of the genitourinary system	0.641	0.359
M84.1 Nonunion of fracture [pseudarthrosis]	0.641	0.359
N00-N08 Glomerular diseases	0.640	0.360
F43.0 Acute stress reaction	0.639	0.361
M83 Adult osteomalacia	0.638	0.362
S51 Open wound of forearm	0.638	0.362
C21.8 Overlapping lesion of rectum, anus and anal canal	0.637	0.363
C21.2 Cloacogenic zone	0.637	0.363
G54 Nerve root and plexus disorders	0.637	0.363
D50-D53 Nutritional anaemias	0.637	0.363
C18.6 Descending colon	0.637	0.363
C43.3 Malignant melanoma of other and unspecified parts of face	0.637	0.363
Y44 Agents primarily affecting blood constituents	0.636	0.363
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.636	0.364
F33.8 Other recurrent depressive disorders	0.636	0.364
F33.4 Recurrent depressive disorder, currently in remission	0.636	0.364
F33.0 Recurrent depressive disorder, current episode mild	0.636	0.364
M25.84 Other specified joint disorders (Hand)	0.636	0.364
E46 Unspecified protein-energy malnutrition	0.634	0.366
M19.97 Arthrosis, unspecified (Ankle and foot)	0.634	0.366
C71.9 Brain, unspecified	0.633	0.366
M75.9 Shoulder lesion, unspecified	0.633	0.367
M24.1 Other articular cartilage disorders	0.633	0.367
J09-J18 Influenza and pneumonia	0.632	0.368
G62 Other polyneuropathies	0.632	0.368
N91 Absent, scanty and rare menstruation	0.632	0.368
Y59 Other and unspecified vaccines and biological substances	0.632	0.368
Y58 Bacterial vaccines	0.632	0.368
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.632	0.368
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.632	0.368
Y53 Agents primarily affecting the gastro-intestinal system	0.632	0.368
Y50 Central nervous system stimulants, not elsewhere classified	0.632	0.368
Y48 Anaesthetics and therapeutic gases	0.632	0.368
Y47 Sedatives, hypnotics and antianxiety drugs	0.632	0.368
Y46 Antiepileptics and anti-Parkinsonism drugs	0.632	0.368
S01 Open wound of head	0.632	0.368
E21.3 Hyperparathyroidism, unspecified	0.631	0.369
W25 Contact with sharp glass	0.631	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations