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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0032
log Bayes Factor = 255.737
contains 12 variants:
rs113994472
lBF = 15.039
Chr 1 : 26,737,645
rs115445154
lBF = 14.884
Chr 1 : 81,921,812
rs74859699
lBF = 18.333
Chr 1 : 154,739,875
rs999091
lBF = 22.670
Chr 2 : 66,603,934
rs17880984
lBF = 14.329
Chr 3 : 3,127,122
rs78424619
lBF = 12.101
Chr 4 : 128,704,037
rs77282735
lBF = 12.719
Chr 7 : 45,090,949
rs77499291
lBF = 13.246
Chr10 : 121,191,404
rs45570136
lBF = 13.370
Chr11 : 113,806,744
rs78574971
lBF = 12.940
Chr12 : 52,023,925
rs76776920
lBF = 13.269
Chr13 : 101,763,029
rs74577983
lBF = 12.655
Chr17 : 5,392,791
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
1.000 0.000 0.000
M47.82 Other spondylosis (Cervical region)
1.000 0.000 0.000
M47.8 Other spondylosis
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
1.000 0.000 0.000
I42 Cardiomyopathy
1.000 0.000 0.000
I47 Paroxysmal tachycardia
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
M47 Spondylosis
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
J95-J99 Other diseases of the respiratory system
1.000 0.000 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Q61 Cystic kidney disease
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M54.56 Low back pain (Lumbar region)
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
Q60-Q64 Congenital malformations of the urinary system
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E86 Volume depletion
1.000 0.000 0.000
H90-H95 Other disorders of ear
1.000 0.000 0.000
M47.9 Spondylosis, unspecified
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
S90-S99 Injuries to the ankle and foot
1.000 0.000 0.000
M51 Other intervertebral disk disorders
1.000 0.000 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
I47.2 Ventricular tachycardia
1.000 0.000 0.000
B35-B49 Mycoses
1.000 0.000 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
1.000 0.000 0.000
I05-I09 Chronic rheumatic heart diseases
1.000 0.000 0.000
M50 Cervical disk disorders
1.000 0.000 0.000
M46 Other inflammatory spondylopathies
1.000 0.000 0.000
M25.7 Osteophyte
1.000 0.000 0.000
I42.0 Dilated cardiomyopathy
1.000 0.000 0.000
M40-M43 Deforming dorsopathies
1.000 0.000 0.000
M46.9 Inflammatory spondylopathy, unspecified
1.000 0.000 0.000
K75 Other inflammatory liver diseases
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.999 0.001 0.000
M24 Other specific joint derangements
0.999 0.001 0.000
I50 Heart failure
0.999 0.001 0.000
M79.0 Rheumatism, unspecified
0.999 0.001 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.999 0.001 0.000
M51.2 Other specified intervertebral disk displacement
0.999 0.001 0.000
B37 Candidiasis
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.999 0.001 0.000
M47.86 Other spondylosis (Lumbar region)
0.999 0.001 0.000
J98 Other respiratory disorders
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
F10.2 Dependence syndrome
0.999 0.001 0.000
Q61.3 Polycystic kidney, unspecified
0.999 0.001 0.000
F10.3 Withdrawal state
0.999 0.001 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.999 0.001 0.000
I50.0 Congestive heart failure
0.999 0.001 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.999 0.001 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.998 0.002 0.000
F10.1 Harmful use
0.998 0.002 0.000
N17-N19 Renal failure
0.998 0.002 0.000
I42.9 Cardiomyopathy, unspecified
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
M21 Other acquired deformities of limbs
0.998 0.002 0.000
M50.1 Cervical disk disorder with radiculopathy
0.998 0.002 0.000
M84 Disorders of continuity of bone
0.998 0.002 0.000
I95 Hypotension
0.998 0.002 0.000
G90-G99 Other disorders of the nervous system
0.998 0.002 0.000
M86-M90 Other osteopathies
0.998 0.002 0.000
S70-S79 Injuries to the hip and thigh
0.998 0.002 0.000
M41 Scoliosis
0.997 0.003 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.997 0.003 0.000
E00-E07 Disorders of thyroid gland
0.997 0.003 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.997 0.003 0.000
I51.9 Heart disease, unspecified
0.997 0.003 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.997 0.003 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.997 0.003 0.000
N17 Acute renal failure
0.997 0.003 0.000
I45 Other conduction disorders
0.997 0.003 0.000
E65-E68 Obesity and other hyperalimentation
0.997 0.003 0.000
M79.1 Myalgia
0.996 0.004 0.000
B37.0 Candidal stomatitis
0.996 0.004 0.000
M41.9 Scoliosis, unspecified
0.996 0.004 0.000
I27 Other pulmonary heart diseases
0.996 0.004 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.996 0.004 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.996 0.004 0.000
I95.1 Orthostatic hypotension
0.995 0.005 0.000
Y52 Agents primarily affecting the cardiovascular system
0.995 0.005 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.995 0.005 0.000
K05 Gingivitis and periodontal diseases
0.995 0.005 0.000
T91 Sequelae of injuries of neck and trunk
0.995 0.005 0.000
N17.9 Acute renal failure, unspecified
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.994 0.006 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.994 0.006 0.000
M54.4 Lumbago with sciatica
0.994 0.006 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.994 0.006 0.000
S80-S89 Injuries to the knee and lower leg
0.994 0.006 0.000
R25 Abnormal involuntary movements
0.994 0.006 0.000
E66 Obesity
0.994 0.006 0.000
T90 Sequelae of injuries of head
0.994 0.006 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
D68 Other coagulation defects
0.993 0.007 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.993 0.007 0.000
Q61.2 Polycystic kidney, adult type
0.993 0.007 0.000
T92 Sequelae of injuries of upper limb
0.993 0.007 0.000
M89 Other disorders of bone
0.992 0.008 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.992 0.008 0.000
R27 Other lack of coordination
0.992 0.008 0.000
T87 Complications peculiar to reattachment and amputation
0.992 0.008 0.000
L60-L75 Disorders of skin appendages
0.992 0.008 0.000
S00-S09 Injuries to the head
0.991 0.009 0.000
M25.78 Osteophyte (Other)
0.991 0.009 0.000
S10-S19 Injuries to the neck
0.991 0.009 0.000
B37.3 Candidiasis of vulva and vagina
0.990 0.010 0.000
H90 Conductive and sensorineural hearing loss
0.990 0.010 0.000
E66.8 Other obesity
0.990 0.010 0.000
E27 Other disorders of adrenal gland
0.989 0.011 0.000
E03 Other hypothyroidism
0.989 0.011 0.000
I05 Rheumatic mitral valve diseases
0.989 0.011 0.000
D45 Polycythaemia vera
0.989 0.011 0.000
B02 Zoster [herpes zoster]
0.989 0.011 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.988 0.012 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.988 0.012 0.000
R44.0 Auditory hallucinations
0.987 0.013 0.000
J98.8 Other specified respiratory disorders
0.987 0.013 0.000
M79.19 Myalgia (Site unspecified)
0.987 0.013 0.000
M54.9 Dorsalgia, unspecified
0.987 0.013 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.986 0.014 0.000
D75 Other diseases of blood and blood-forming organs
0.986 0.014 0.000
D72 Other disorders of white blood cells
0.986 0.014 0.000
S90 Superficial injury of ankle and foot
0.986 0.014 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.986 0.014 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.986 0.014 0.000
M34 Systemic sclerosis
0.985 0.015 0.000
Y42.7 Androgens and anabolic congeners
0.985 0.015 0.000
K70 Alcoholic liver disease
0.985 0.015 0.000
M91-M94 Chondropathies
0.985 0.015 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.985 0.015 0.000
M85 Other disorders of bone density and structure
0.985 0.015 0.000
H93 Other disorders of ear, not elsewhere classified
0.984 0.016 0.000
I07 Rheumatic tricuspid valve diseases
0.984 0.016 0.000
I51.8 Other ill-defined heart diseases
0.984 0.016 0.000
Y43 Primarily systemic agents
0.984 0.016 0.000
Y88 Sequelae of surgical and medical care as external cause
0.984 0.016 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.984 0.016 0.000
I81 Portal vein thrombosis
0.984 0.016 0.000
I87 Other disorders of veins
0.984 0.016 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.983 0.017 0.000
M54.3 Sciatica
0.983 0.017 0.000
S40-S49 Injuries to the shoulder and upper arm
0.983 0.017 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.983 0.017 0.000
I47.1 Supraventricular tachycardia
0.983 0.017 0.000
L73 Other follicular disorders
0.983 0.017 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.983 0.017 0.000
F10.0 Acute intoxication
0.982 0.018 0.000
R44.1 Visual hallucinations
0.981 0.019 0.000
S70 Superficial injury of hip and thigh
0.981 0.019 0.000
K75.0 Abscess of liver
0.980 0.020 0.000
S60-S69 Injuries to the wrist and hand
0.980 0.020 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.979 0.021 0.000
I27.0 Primary pulmonary hypertension
0.979 0.021 0.000
J95.8 Other postprocedural respiratory disorders
0.979 0.021 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.977 0.023 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.977 0.023 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.977 0.023 0.000
M79.7 Fibromyalgia
0.976 0.024 0.000
R40 Somnolence, stupor and coma
0.976 0.024 0.000
Chapter VII Diseases of the eye and adnexa
0.976 0.024 0.000
T87.6 Other and unspecified complications of amputation stump
0.976 0.024 0.000
M60-M63 Disorders of muscles
0.976 0.024 0.000
L73.9 Follicular disorder, unspecified
0.976 0.024 0.000
E03.9 Hypothyroidism, unspecified
0.976 0.024 0.000
S06 Intracranial injury
0.975 0.025 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
Q80-Q89 Other congenital malformations
0.975 0.025 0.000
C17 Malignant neoplasm of small intestine
0.975 0.025 0.000
M54.2 Cervicalgia
0.974 0.026 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.974 0.026 0.000
I07.1 Tricuspid insufficiency
0.974 0.026 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.973 0.027 0.000
L20-L30 Dermatitis and eczema
0.973 0.027 0.000
K08 Other disorders of teeth and supporting structures
0.973 0.027 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.972 0.028 0.000
M47.1 Other spondylosis with myelopathy
0.972 0.028 0.000
H65-H75 Diseases of middle ear and mastoid
0.972 0.028 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.972 0.028 0.000
W00-W19 Falls
0.971 0.029 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.970 0.030 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.970 0.030 0.000
K75.9 Inflammatory liver disease, unspecified
0.970 0.030 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.970 0.030 0.000
H93.1 Tinnitus
0.969 0.031 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.969 0.031 0.000
M43 Other deforming dorsopathies
0.969 0.031 0.000
I87.1 Compression of vein
0.968 0.032 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.968 0.032 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.967 0.033 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.967 0.033 0.000
W20-W49 Exposure to inanimate mechanical forces
0.967 0.033 0.000
D72.8 Other specified disorders of white blood cells
0.967 0.033 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.966 0.034 0.000
R27.0 Ataxia, unspecified
0.966 0.034 0.000
G30-G32 Other degenerative diseases of the nervous system
0.966 0.034 0.000
K75.8 Other specified inflammatory liver diseases
0.965 0.035 0.000
I27.2 Other secondary pulmonary hypertension
0.965 0.035 0.000
E07 Other disorders of thyroid
0.965 0.035 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.964 0.036 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.964 0.036 0.000
J00-J06 Acute upper respiratory infections
0.964 0.036 0.000
H55-H59 Other disorders of eye and adnexa
0.964 0.036 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.963 0.037 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.963 0.037 0.000
C71 Malignant neoplasm of brain
0.962 0.038 0.000
R40.2 Coma, unspecified
0.962 0.038 0.000
M85.0 Fibrous dysplasia (monostotic)
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.962 0.038 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.961 0.039 0.000
I45.9 Conduction disorder, unspecified
0.961 0.039 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.960 0.040 0.000
Chapter XXII Codes for special purposes
0.960 0.040 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.960 0.040 0.000
K10 Other diseases of jaws
0.959 0.041 0.000
G70-G73 Diseases of myoneural junction and muscle
0.958 0.042 0.000
N18 Chronic renal failure
0.958 0.042 0.000
D75.2 Essential thrombocytosis
0.958 0.042 0.000
C01 Malignant neoplasm of base of tongue
0.957 0.043 0.000
M25.3 Other instability of joint
0.957 0.043 0.000
M21.2 Flexion deformity
0.956 0.044 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.956 0.044 0.000
T81 Complications of procedures, not elsewhere classified
0.956 0.044 0.000
S50-S59 Injuries to the elbow and forearm
0.956 0.044 0.000
K12 Stomatitis and related lesions
0.956 0.044 0.000
M62 Other disorders of muscle
0.955 0.045 0.000
S64 Injury of nerves at wrist and hand level
0.955 0.045 0.000
K13 Other diseases of lip and oral mucosa
0.954 0.046 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.954 0.046 0.000
H92 Otalgia and effusion of ear
0.954 0.046 0.000
T40.2 Other opioids
0.953 0.047 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.953 0.047 0.000
N00-N08 Glomerular diseases
0.953 0.047 0.000
M54.37 Sciatica (Lumbosacral region)
0.953 0.047 0.000
M47.2 Other spondylosis with radiculopathy
0.953 0.047 0.000
N70 Salpingitis and oophoritis
0.953 0.047 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
M80 Osteoporosis with pathological fracture
0.952 0.048 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.952 0.048 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.952 0.048 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.952 0.048 0.000
M25.8 Other specified joint disorders
0.951 0.049 0.000
H57 Other disorders of eye and adnexa
0.951 0.049 0.000
I77 Other disorders of arteries and arterioles
0.951 0.049 0.000
I44 Atrioventricular and left bundle-branch block
0.950 0.050 0.000
M77 Other enthesopathies
0.950 0.050 0.000
N18.9 Chronic renal failure, unspecified
0.950 0.050 0.000
S99 Other and unspecified injuries of ankle and foot
0.950 0.050 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.949 0.051 0.000
K05.3 Chronic periodontitis
0.949 0.051 0.000
J00 Acute nasopharyngitis [common cold]
0.949 0.051 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.949 0.051 0.000
B00 Herpesviral [herpes simplex] infections
0.949 0.051 0.000
E29 Testicular dysfunction
0.948 0.052 0.000
B15-B19 Viral hepatitis
0.948 0.052 0.000
G58 Other mononeuropathies
0.948 0.052 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.947 0.053 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.947 0.053 0.000
T93 Sequelae of injuries of lower limb
0.947 0.053 0.000
M25.9 Joint disorder, unspecified
0.947 0.053 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.946 0.054 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.945 0.055 0.000
K35-K38 Diseases of appendix
0.945 0.055 0.000
M24.1 Other articular cartilage disorders
0.945 0.055 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.945 0.055 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.943 0.057 0.000
R26 Abnormalities of gait and mobility
0.943 0.057 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.942 0.058 0.000
E27.1 Primary adrenocortical insufficiency
0.942 0.058 0.000
S06.3 Focal brain injury
0.942 0.058 0.000
M89.8 Other specified disorders of bone
0.942 0.058 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.941 0.059 0.000
M62.8 Other specified disorders of muscle
0.941 0.059 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.940 0.060 0.000
M34.1 CR(E)ST syndrome
0.940 0.060 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.940 0.060 0.000
M79.79 Fibromyalgia (Site unspecified)
0.940 0.060 0.000
M43.0 Spondylolysis
0.939 0.061 0.000
I60-I69 Cerebrovascular diseases
0.939 0.061 0.000
Y00-Y09 Assault
0.939 0.061 0.000
Q50-Q56 Congenital malformations of genital organs
0.939 0.061 0.000
M25.71 Osteophyte (Shoulder region)
0.939 0.061 0.000
C26.0 Intestinal tract, part unspecified
0.938 0.062 0.000
E50-E64 Other nutritional deficiencies
0.938 0.062 0.000
T86 Failure and rejection of transplanted organs and tissues
0.938 0.062 0.000
S05 Injury of eye and orbit
0.938 0.062 0.000
R45 Symptoms and signs involving emotional state
0.938 0.062 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.937 0.063 0.000
R80 Isolated proteinuria
0.937 0.063 0.000
H66 Suppurative and unspecified otitis media
0.937 0.063 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.937 0.063 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.937 0.063 0.000
B02.9 Zoster without complication
0.937 0.063 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.937 0.063 0.000
K70.9 Alcoholic liver disease, unspecified
0.936 0.064 0.000
L60 Nail disorders
0.935 0.065 0.000
S20-S29 Injuries to the thorax
0.935 0.065 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.935 0.065 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.935 0.065 0.000
I77.6 Arteritis, unspecified
0.935 0.065 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.935 0.065 0.000
Q00-Q07 Congenital malformations of the nervous system
0.934 0.066 0.000
T66-T78 Other and unspecified effects of external causes
0.934 0.066 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.934 0.066 0.000
M24.0 Loose body in joint
0.933 0.067 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.933 0.067 0.000
Q18 Other congenital malformations of face and neck
0.933 0.067 0.000
R25.3 Fasciculation
0.932 0.068 0.000
L28 Lichen simplex chronicus and prurigo
0.932 0.068 0.000
F30-F39 Mood [affective] disorders
0.932 0.068 0.000
J98.9 Respiratory disorder, unspecified
0.932 0.068 0.000
M21.4 Flat foot [pes planus] (acquired)
0.931 0.069 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.931 0.069 0.000
H74 Other disorders of middle ear and mastoid
0.931 0.069 0.000
M54.29 Cervicalgia-Site unspe
0.931 0.069 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.930 0.070 0.000
I62 Other nontraumatic intracranial haemorrhage
0.930 0.070 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.930 0.070 0.000
K74 Fibrosis and cirrhosis of liver
0.929 0.071 0.000
V40-V49 Car occupant injured in transport accident
0.929 0.071 0.000
T90.9 Sequelae of unspecified injury of head
0.928 0.072 0.000
S82 Fracture of lower leg, including ankle
0.928 0.072 0.000
S50 Superficial injury of forearm
0.928 0.072 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.928 0.072 0.000
R27.8 Other and unspecified lack of coordination
0.927 0.073 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.927 0.073 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.927 0.073 0.000
F45 Somatoform disorders
0.927 0.073 0.000
I36 Nonrheumatic tricuspid valve disorders
0.927 0.073 0.000
A30-A49 Other bacterial diseases
0.927 0.073 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.927 0.073 0.000
H92.1 Otorrhoea
0.927 0.073 0.000
M06 Other rheumatoid arthritis
0.927 0.073 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.926 0.074 0.000
I08 Multiple valve diseases
0.926 0.074 0.000
I05.0 Mitral stenosis
0.926 0.074 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.926 0.074 0.000
S71 Open wound of hip and thigh
0.925 0.075 0.000
G90 Disorders of autonomic nervous system
0.925 0.075 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.924 0.076 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.922 0.078 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.922 0.078 0.000
K05.1 Chronic gingivitis
0.922 0.078 0.000
M34.9 Systemic sclerosis, unspecified
0.922 0.078 0.000
R77 Other abnormalities of plasma proteins
0.921 0.079 0.000
D47.1 Chronic myeloproliferative disease
0.921 0.079 0.000
R26.3 Immobility
0.921 0.079 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.921 0.079 0.000
D10-D36 Benign neoplasms
0.920 0.080 0.000
M21.0 Valgus deformity, not elsewhere classified
0.920 0.080 0.000
R23 Other skin changes
0.920 0.080 0.000
K11 Diseases of salivary glands
0.919 0.081 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.919 0.081 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.918 0.082 0.000
Y85 Sequelae of transport accidents
0.918 0.082 0.000
B44 Aspergillosis
0.918 0.082 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.918 0.082 0.000
X60-X84 Intentional self-harm
0.917 0.083 0.000
D26 Other benign neoplasms of uterus
0.917 0.083 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.917 0.083 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.917 0.083 0.000
S82.4 Fracture of fibula alone
0.917 0.083 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.916 0.084 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.916 0.084 0.000
M24.2 Disorder of ligament
0.916 0.084 0.000
G54 Nerve root and plexus disorders
0.916 0.084 0.000
S14 Injury of nerves and spinal cord at neck level
0.915 0.085 0.000
T88.5 Other complications of anaesthesia
0.915 0.085 0.000
B49 Unspecified mycosis
0.915 0.085 0.000
I45.2 Bifascicular block
0.914 0.086 0.000
I82 Other venous embolism and thrombosis
0.914 0.086 0.000
M06.0 Seronegative rheumatoid arthritis
0.914 0.086 0.000
W50-W64 Exposure to animate mechanical forces
0.914 0.086 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.913 0.087 0.000
K72 Hepatic failure, not elsewhere classified
0.913 0.087 0.000
C22.9 Liver, unspecified
0.913 0.087 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.913 0.087 0.000
I88 Nonspecific lymphadenitis
0.913 0.087 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.913 0.087 0.000
I44.3 Other and unspecified atrioventricular block
0.913 0.087 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.912 0.088 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.912 0.088 0.000
E29.1 Testicular hypofunction
0.912 0.088 0.000
C92 Myeloid leukaemia
0.912 0.088 0.000
I49 Other cardiac arrhythmias
0.911 0.089 0.000
C81 Hodgkin's disease
0.911 0.089 0.000
T90.4 Sequelae of injury of eye and orbit
0.911 0.089 0.000
D68.2 Hereditary deficiency of other clotting factors
0.911 0.089 0.000
S00 Superficial injury of head
0.910 0.090 0.000
J10 Influenza due to identified influenza virus
0.910 0.090 0.000
I49.3 Ventricular premature depolarisation
0.909 0.091 0.000
S82.40 Fracture of fibula alone (closed)
0.909 0.091 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.908 0.092 0.000
S06.8 Other intracranial injuries
0.908 0.092 0.000
K05.6 Periodontal disease, unspecified
0.908 0.092 0.000
I05.2 Mitral stenosis with insufficiency
0.908 0.092 0.000
Y43.4 Immunosuppressive agents
0.908 0.092 0.000
M79.6 Pain in limb
0.907 0.093 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.907 0.093 0.000
E74 Other disorders of carbohydrate metabolism
0.907 0.093 0.000
M92 Other juvenile osteochondrosis
0.907 0.093 0.000
M79.8 Other specified soft tissue disorders
0.906 0.094 0.000
L73.8 Other specified follicular disorders
0.906 0.094 0.000
K38 Other diseases of appendix
0.906 0.094 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.906 0.094 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.906 0.094 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.904 0.096 0.000
S12 Fracture of neck
0.904 0.096 0.000
I45.8 Other specified conduction disorders
0.904 0.096 0.000
J60-J70 Lung diseases due to external agents
0.903 0.097 0.000
F33 Recurrent depressive disorder
0.903 0.097 0.000
C45 Mesothelioma
0.902 0.098 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.902 0.098 0.000
Y54.3 Benzothiadiazine derivatives
0.902 0.098 0.000
B02.2 Zoster with other nervous system involvement
0.902 0.098 0.000
M54.55 Low back pain (Thoracolumbar region)
0.902 0.098 0.000
J01 Acute sinusitis
0.901 0.099 0.000
Y40 Systemic antibiotics
0.901 0.099 0.000
T23 Burn and corrosion of wrist and hand
0.901 0.099 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.900 0.100 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.900 0.100 0.000
Y43.1 Antineoplastic antimetabolites
0.900 0.100 0.000
B02.3 Zoster ocular disease
0.900 0.100 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.900 0.100 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.899 0.101 0.000
R23.1 Pallor
0.899 0.101 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.899 0.101 0.000
M54.36 Sciatica (Lumbar region)
0.899 0.101 0.000
F80-F89 Disorders of psychological development
0.899 0.101 0.000
T92.1 Sequelae of fracture of arm
0.899 0.101 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.898 0.102 0.000
H57.1 Ocular pain
0.898 0.102 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.898 0.102 0.000
C17.0 Duodenum
0.898 0.102 0.000
M43.06 Spondylolysis (Lumbar region)
0.897 0.103 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.897 0.103 0.000
K10.8 Other specified diseases of jaws
0.897 0.103 0.000
S93.1 Dislocation of toe(s)
0.896 0.104 0.000
D26.1 Corpus uteri
0.896 0.104 0.000
G95 Other diseases of spinal cord
0.896 0.104 0.000
I20-I25 Ischaemic heart diseases
0.896 0.104 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.895 0.105 0.000
E07.9 Disorder of thyroid, unspecified
0.895 0.105 0.000
Y57 Other and unspecified drugs and medicaments
0.895 0.105 0.000
C25 Malignant neoplasm of pancreas
0.894 0.106 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.894 0.106 0.000
M89.5 Osteolysis
0.894 0.106 0.000
S99.9 Unspecified injury of ankle and foot
0.893 0.107 0.000
M48 Other spondylopathies
0.893 0.107 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.893 0.107 0.000
W18 Other fall on same level
0.893 0.107 0.000
D32 Benign neoplasm of meninges
0.893 0.107 0.000
R25.2 Cramp and spasm
0.892 0.108 0.000
M50.2 Other cervical disk displacement
0.892 0.108 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.892 0.108 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.891 0.109 0.000
G31.8 Other specified degenerative diseases of nervous system
0.891 0.109 0.000
S92 Fracture of foot, except ankle
0.891 0.109 0.000
S64.3 Injury of digital nerve of thumb
0.891 0.109 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.891 0.109 0.000
C71.1 Frontal lobe
0.890 0.110 0.000
F43 Reaction to severe stress, and adjustment disorders
0.890 0.110 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.890 0.110 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.889 0.111 0.000
Y48 Anaesthetics and therapeutic gases
0.889 0.111 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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