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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116260971
log Bayes Factor = 14.538
Chromosome 2   position 66,345,333  (GRCh37) Explore rs116260971 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
M80-M85 Disorders of bone density and structure
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.994 0.006 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.993 0.007 0.000
M75 Shoulder lesions
0.992 0.008 0.000
I60-I69 Cerebrovascular diseases
0.991 0.009 0.000
M81 Osteoporosis without pathological fracture
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
M81.9 Osteoporosis, unspecified
0.984 0.016 0.000
E10 Insulin-dependent diabetes mellitus
0.982 0.018 0.000
S60-S69 Injuries to the wrist and hand
0.981 0.019 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
I50 Heart failure
0.974 0.026 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.968 0.032 0.000
Chapter I Certain infectious and parasitic diseases
0.967 0.033 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.964 0.036 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
N17-N19 Renal failure
0.957 0.043 0.000
M75.0 Adhesive capsulitis of shoulder
0.955 0.045 0.000
I50.0 Congestive heart failure
0.952 0.048 0.000
W20-W49 Exposure to inanimate mechanical forces
0.950 0.050 0.000
E11 Non-insulin-dependent diabetes mellitus
0.941 0.059 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.940 0.060 0.000
N18 Chronic renal failure
0.935 0.065 0.000
M25 Other joint disorders, not elsewhere classified
0.933 0.067 0.000
O00-O08 Pregnancy with abortive outcome
0.930 0.070 0.000
N20-N23 Urolithiasis
0.925 0.075 0.000
E10.4 With neurological complications
0.925 0.075 0.000
Chapter X Diseases of the respiratory system
0.921 0.079 0.000
M23 Internal derangement of knee
0.917 0.083 0.000
S61 Open wound of wrist and hand
0.914 0.086 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.913 0.087 0.000
I51 Complications and ill-defined descriptions of heart disease
0.912 0.088 0.000
N18.3 Chronic kidney disease, stage 3
0.911 0.089 0.000
M75.4 Impingement syndrome of shoulder
0.896 0.104 0.000
I63 Cerebral infarction
0.896 0.104 0.000
S70-S79 Injuries to the hip and thigh
0.895 0.105 0.000
M75.1 Rotator cuff syndrome
0.894 0.106 0.000
W22 Striking against or struck by other objects
0.893 0.107 0.000
N20 Calculus of kidney and ureter
0.892 0.108 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
S61.0 Open wound of finger(s) without damage to nail
0.889 0.111 0.000
M21 Other acquired deformities of limbs
0.886 0.114 0.000
I61 Intracerebral haemorrhage
0.885 0.115 0.000
M15-M19 Arthrosis
0.883 0.117 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.880 0.120 0.000
I50.1 Left ventricular failure
0.878 0.122 0.000
W00-W19 Falls
0.876 0.124 0.000
I42 Cardiomyopathy
0.876 0.124 0.000
N00-N08 Glomerular diseases
0.874 0.126 0.000
Chapter VI Diseases of the nervous system
0.871 0.129 0.000
X60-X84 Intentional self-harm
0.871 0.129 0.000
M25.5 Pain in joint
0.866 0.134 0.000
O04 Medical abortion
0.864 0.136 0.000
B35-B49 Mycoses
0.859 0.141 0.000
I69 Sequelae of cerebrovascular disease
0.859 0.141 0.000
J90-J94 Other diseases of pleura
0.858 0.142 0.000
S64 Injury of nerves at wrist and hand level
0.853 0.147 0.000
W22.9 Unspecified place
0.853 0.147 0.000
I50.9 Heart failure, unspecified
0.851 0.149 0.000
N20.1 Calculus of ureter
0.848 0.152 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.842 0.158 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.839 0.161 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.837 0.163 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.837 0.163 0.000
S00-S09 Injuries to the head
0.835 0.165 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.833 0.167 0.000
M24 Other specific joint derangements
0.827 0.173 0.000
E10.5 With peripheral circulatory complications
0.827 0.173 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.825 0.175 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.823 0.177 0.000
M16 Coxarthrosis [arthrosis of hip]
0.821 0.179 0.000
M75.3 Calcific tendinitis of shoulder
0.818 0.182 0.000
N18.4 Chronic kidney disease, stage 4
0.818 0.182 0.000
E10.8 With unspecified complications
0.814 0.186 0.000
I63.9 Cerebral infarction, unspecified
0.814 0.186 0.000
O02 Other abnormal products of conception
0.813 0.187 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.813 0.187 0.000
M45-M49 Spondylopathies
0.812 0.188 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.811 0.189 0.000
M75.5 Bursitis of shoulder
0.811 0.189 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.811 0.189 0.000
M23.4 Loose body in knee
0.809 0.191 0.000
E11.2 With renal complications
0.808 0.192 0.000
E50-E64 Other nutritional deficiencies
0.807 0.193 0.000
T66-T78 Other and unspecified effects of external causes
0.806 0.194 0.000
N19 Unspecified renal failure
0.805 0.195 0.000
I51.8 Other ill-defined heart diseases
0.804 0.196 0.000
M23.3 Other meniscus derangements
0.803 0.197 0.000
E14 Unspecified diabetes mellitus
0.798 0.202 0.000
M25.8 Other specified joint disorders
0.796 0.204 0.000
V10-V19 Pedal cyclist injured in transport accident
0.795 0.205 0.000
E10.9 Without complications
0.793 0.207 0.000
A00-A09 Intestinal infectious diseases
0.788 0.212 0.000
E65-E68 Obesity and other hyperalimentation
0.787 0.213 0.000
S40-S49 Injuries to the shoulder and upper arm
0.787 0.213 0.000
Chapter II Neoplasms
0.787 0.213 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
M81.4 Drug-induced osteoporosis
0.785 0.215 0.000
S79 Other and unspecified injuries of hip and thigh
0.785 0.215 0.000
E11.3 With ophthalmic complications
0.785 0.215 0.000
M85 Other disorders of bone density and structure
0.784 0.216 0.000
W25 Contact with sharp glass
0.782 0.218 0.000
O04.9 Complete or unspecified, without complication
0.782 0.218 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.781 0.219 0.000
E10.2 With renal complications
0.781 0.219 0.000
M80 Osteoporosis with pathological fracture
0.780 0.220 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.779 0.221 0.000
B25-B34 Other viral diseases
0.779 0.221 0.000
N72 Inflammatory disease of cervix uteri
0.779 0.221 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.778 0.222 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.777 0.222 0.000
M16.9 Coxarthrosis, unspecified
0.776 0.224 0.000
N99-N99 Other disorders of the genitourinary system
0.775 0.225 0.000
N10-N16 Renal tubulo-interstitial diseases
0.775 0.225 0.000
Q60-Q64 Congenital malformations of the urinary system
0.772 0.228 0.000
M75.2 Bicipital tendinitis
0.771 0.229 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.771 0.229 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.770 0.230 0.000
M25.57 Pain in joint (Ankle and foot)
0.769 0.231 0.000
J95-J99 Other diseases of the respiratory system
0.769 0.231 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.769 0.231 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.768 0.232 0.000
M34 Systemic sclerosis
0.767 0.232 0.000
M25.56 Pain in joint (Lower leg)
0.766 0.234 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.762 0.238 0.000
S68 Traumatic amputation of wrist and hand
0.762 0.238 0.000
J09-J18 Influenza and pneumonia
0.761 0.239 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.761 0.239 0.000
S00 Superficial injury of head
0.759 0.241 0.000
I51.9 Heart disease, unspecified
0.758 0.242 0.000
M91-M94 Chondropathies
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
E10.3 With ophthalmic complications
0.754 0.245 0.000
S67 Crushing injury of wrist and hand
0.754 0.246 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.752 0.248 0.000
S80-S89 Injuries to the knee and lower leg
0.751 0.249 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.751 0.249 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
M20 Acquired deformities of fingers and toes
0.750 0.250 0.000
I42.8 Other cardiomyopathies
0.749 0.251 0.000
S90-S99 Injuries to the ankle and foot
0.748 0.252 0.000
M40-M43 Deforming dorsopathies
0.747 0.253 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
A30-A49 Other bacterial diseases
0.743 0.257 0.000
E11.1 With ketoacidosis
0.742 0.258 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.741 0.259 0.000
M86-M90 Other osteopathies
0.740 0.259 0.000
M77 Other enthesopathies
0.740 0.260 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.740 0.260 0.000
V20-V29 Motorcycle rider injured in transport accident
0.740 0.260 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.740 0.260 0.000
T42.4 Benzodiazepines
0.738 0.262 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.737 0.263 0.000
E11.6 With other specified complications
0.737 0.263 0.000
N75 Diseases of Bartholin's gland
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.735 0.264 0.000
N20.0 Calculus of kidney
0.735 0.265 0.000
M21.1 Varus deformity, not elsewhere classified
0.735 0.265 0.000
B95-B98 Bacterial, viral and other infectious agents
0.734 0.266 0.000
M19 Other arthrosis
0.734 0.266 0.000
S64.3 Injury of digital nerve of thumb
0.734 0.266 0.000
M84 Disorders of continuity of bone
0.733 0.266 0.000
B37 Candidiasis
0.732 0.268 0.000
I73 Other peripheral vascular diseases
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.731 0.268 0.000
N71 Inflammatory disease of uterus, except cervix
0.731 0.269 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.731 0.269 0.000
M23.49 Loose body in knee-Unspec lig/men
0.731 0.269 0.000
E11.5 With peripheral circulatory complications
0.731 0.269 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.730 0.270 0.000
O02.1 Missed abortion
0.730 0.270 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.729 0.271 0.000
S60 Superficial injury of wrist and hand
0.728 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.728 0.272 0.000
J92 Pleural plaque
0.728 0.272 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.726 0.274 0.000
E40-E46 Malnutrition
0.725 0.275 0.000
M21.2 Flexion deformity
0.725 0.275 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.724 0.276 0.000
Chapter VIII Diseases of the ear and mastoid process
0.724 0.276 0.000
M81.98 Osteoporosis, unspecified (Other)
0.723 0.277 0.000
M71 Other bursopathies
0.723 0.277 0.000
S62 Fracture at wrist and hand level
0.720 0.280 0.000
J90 Pleural effusion, not elsewhere classified
0.719 0.281 0.000
I51.7 Cardiomegaly
0.719 0.281 0.000
I60 Subarachnoid haemorrhage
0.718 0.281 0.000
O03 Spontaneous abortion
0.718 0.282 0.000
I62 Other nontraumatic intracranial haemorrhage
0.718 0.282 0.000
I10-I15 Hypertensive diseases
0.718 0.282 0.000
I42.9 Cardiomyopathy, unspecified
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
I47 Paroxysmal tachycardia
0.716 0.284 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.715 0.285 0.000
M83 Adult osteomalacia
0.714 0.286 0.000
M82 Osteoporosis in diseases classified elsewhere
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
M75.8 Other shoulder lesions
0.712 0.288 0.000
M75.9 Shoulder lesion, unspecified
0.712 0.288 0.000
N18.2 Chronic kidney disease, stage 2
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
B44 Aspergillosis
0.710 0.290 0.000
M81.8 Other osteoporosis
0.709 0.290 0.000
M81.6 Localised osteoporosis [Lequesne]
0.709 0.290 0.000
M81.5 Idiopathic osteoporosis
0.709 0.290 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.709 0.290 0.000
M81.2 Osteoporosis of disuse
0.709 0.290 0.000
M81.1 Postoophorectomy osteoporosis
0.709 0.290 0.000
M81.0 Postmenopausal osteoporosis
0.709 0.290 0.000
S72 Fracture of femur
0.710 0.290 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.709 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.707 0.293 0.000
M23.8 Other internal derangements of knee
0.707 0.293 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.707 0.293 0.000
S79.9 Unspecified injury of hip and thigh
0.706 0.294 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.706 0.294 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.706 0.294 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.705 0.294 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.705 0.294 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.705 0.294 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.705 0.294 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.705 0.294 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.705 0.294 0.000
E11.4 With neurological complications
0.705 0.295 0.000
E10.1 With ketoacidosis
0.705 0.295 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.705 0.295 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.705 0.295 0.000
W19 Unspecified fall
0.705 0.295 0.000
E10.7 With multiple complications
0.704 0.296 0.000
E10.6 With other specified complications
0.704 0.296 0.000
E10.0 With coma
0.704 0.296 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.704 0.296 0.000
S69 Other and unspecified injuries of wrist and hand
0.703 0.297 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.297 0.000
O80-O84 Delivery
0.703 0.297 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.703 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.700 0.300 0.000
J81 Pulmonary oedema
0.700 0.300 0.000
N70 Salpingitis and oophoritis
0.700 0.300 0.000
X58 Exposure to other specified factors
0.699 0.301 0.000
J94 Other pleural conditions
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.301 0.000
S00.8 Superficial injury of other parts of head
0.698 0.302 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.694 0.306 0.000
E14.3 With ophthalmic complications
0.694 0.306 0.000
B99-B99 Other infectious diseases
0.694 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
B50-B64 Protozoal diseases
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
I33 Acute and subacute endocarditis
0.693 0.307 0.000
M31 Other necrotising vasculopathies
0.693 0.307 0.000
I74 Arterial embolism and thrombosis
0.692 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.691 0.309 0.000
I95 Hypotension
0.691 0.309 0.000
X78 Intentional self-harm by sharp object
0.688 0.311 0.000
Y85 Sequelae of transport accidents
0.688 0.312 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.688 0.312 0.000
J91 Pleural effusion in conditions classified elsewhere
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.687 0.313 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.313 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.687 0.313 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.687 0.313 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.687 0.313 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
T36 Poisoning by systemic antibiotics
0.687 0.313 0.000
W13 Fall from, out of or through building or structure
0.687 0.313 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.687 0.313 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.686 0.314 0.000
M16.0 Primary coxarthrosis, bilateral
0.686 0.314 0.000
M47 Spondylosis
0.686 0.314 0.000
I05-I09 Chronic rheumatic heart diseases
0.685 0.315 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.684 0.316 0.000
W10 Fall on and from stairs and steps
0.684 0.316 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.683 0.317 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.683 0.317 0.000
E00-E07 Disorders of thyroid gland
0.682 0.318 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.681 0.319 0.000
W46 Contact with hypodermic needle
0.681 0.319 0.000
W45 Foreign body or object entering through skin
0.681 0.319 0.000
W44 Foreign body entering into or through eye or natural orifice
0.681 0.319 0.000
W43 Exposure to vibration
0.681 0.319 0.000
W42 Exposure to noise
0.681 0.319 0.000
W41 Exposure to high-pressure jet
0.681 0.319 0.000
W40 Explosion of other materials
0.681 0.319 0.000
W39 Discharge of firework
0.681 0.319 0.000
W38 Explosion and rupture of other specified pressurised devices
0.681 0.319 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.681 0.319 0.000
W36 Explosion and rupture of gas cylinder
0.681 0.319 0.000
W35 Explosion and rupture of boiler
0.681 0.319 0.000
W34 Discharge from other and unspecified firearms
0.681 0.319 0.000
W33 Rifle, shotgun and larger firearm discharge
0.681 0.319 0.000
W32 Handgun discharge
0.681 0.319 0.000
W31 Contact with other and unspecified machinery
0.681 0.319 0.000
W30 Contact with agricultural machinery
0.681 0.319 0.000
W29 Contact with other powered hand tools and household machinery
0.681 0.319 0.000
W28 Contact with powered lawn mower
0.681 0.319 0.000
W27 Contact with nonpowered hand tool
0.681 0.319 0.000
W26 Contact with knife, sword or dagger
0.681 0.319 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.681 0.319 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.681 0.319 0.000
W21 Striking against or struck by sports equipment
0.681 0.319 0.000
W20 Struck by thrown, projected or falling object
0.681 0.319 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.320 0.000
M20.2 Hallux rigidus
0.679 0.321 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.677 0.323 0.000
G90-G99 Other disorders of the nervous system
0.677 0.323 0.000
T51 Toxic effect of alcohol
0.676 0.324 0.000
G20-G26 Extrapyramidal and movement disorders
0.676 0.324 0.000
C79 Secondary malignant neoplasm of other sites
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
N18.5 Chronic kidney disease, stage 5
0.675 0.325 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
E11.7 With multiple complications
0.675 0.325 0.000
E11.0 With coma
0.675 0.325 0.000
E61 Deficiency of other nutrient elements
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.673 0.327 0.000
N21 Calculus of lower urinary tract
0.673 0.327 0.000
N18.8 Other chronic renal failure
0.671 0.329 0.000
N18.1 Chronic kidney disease, stage 1
0.671 0.329 0.000
Y83.8 Other surgical procedures
0.670 0.330 0.000
M25.9 Joint disorder, unspecified
0.669 0.331 0.000
M25.3 Other instability of joint
0.669 0.331 0.000
M25.2 Flail joint
0.669 0.331 0.000
M25.1 Fistula of joint
0.669 0.331 0.000
M25.0 Haemarthrosis
0.669 0.331 0.000
N20.2 Calculus of kidney with calculus of ureter
0.669 0.331 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.669 0.331 0.000
S64.4 Injury of digital nerve of other finger
0.668 0.332 0.000
T78 Adverse effects, not elsewhere classified
0.667 0.333 0.000
M22 Disorders of patella
0.667 0.333 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.667 0.333 0.000
O07 Failed attempted abortion
0.667 0.333 0.000
O06 Unspecified abortion
0.667 0.333 0.000
O05 Other abortion
0.667 0.333 0.000
O01 Hydatidiform mole
0.667 0.333 0.000
M21.0 Valgus deformity, not elsewhere classified
0.666 0.334 0.000
M46 Other inflammatory spondylopathies
0.666 0.334 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.335 0.000
N25-N29 Other disorders of kidney and ureter
0.664 0.336 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.664 0.336 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.664 0.336 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
S05 Injury of eye and orbit
0.664 0.336 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.663 0.336 0.000
M25.53 Pain in joint (Forearm)
0.663 0.337 0.000
W25.9 Unspecified place
0.662 0.338 0.000
M21.3 Wrist or foot drop (acquired)
0.661 0.339 0.000
S70 Superficial injury of hip and thigh
0.660 0.340 0.000
I35 Nonrheumatic aortic valve disorders
0.660 0.340 0.000
I42.2 Other hypertrophic cardiomyopathy
0.659 0.341 0.000
M23.9 Internal derangement of knee, unspecified
0.658 0.342 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.658 0.342 0.000
M23.5 Chronic instability of knee
0.658 0.342 0.000
M23.1 Discoid meniscus (congenital)
0.658 0.342 0.000
M23.0 Cystic meniscus
0.658 0.342 0.000
O00 Ectopic pregnancy
0.656 0.344 0.000
S61.7 Multiple open wounds of wrist and hand
0.655 0.345 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.655 0.345 0.000
W07 Fall involving chair
0.655 0.345 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.654 0.346 0.000
I51.6 Cardiovascular disease, unspecified
0.654 0.346 0.000
I51.5 Myocardial degeneration
0.654 0.346 0.000
I51.4 Myocarditis, unspecified
0.654 0.346 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.654 0.346 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.654 0.346 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.654 0.346 0.000
I51.0 Cardiac septal defect, acquired
0.654 0.346 0.000
I78 Diseases of capillaries
0.654 0.346 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.653 0.347 0.000
M25.84 Other specified joint disorders (Hand)
0.653 0.347 0.000
M19.9 Arthrosis, unspecified
0.652 0.348 0.000
O60-O75 Complications of labour and delivery
0.651 0.348 0.000
T39.1 4-Aminophenol derivatives
0.651 0.349 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.651 0.349 0.000
B00 Herpesviral [herpes simplex] infections
0.651 0.349 0.000
M24.1 Other articular cartilage disorders
0.651 0.349 0.000
Y88 Sequelae of surgical and medical care as external cause
0.650 0.350 0.000
N76 Other inflammation of vagina and vulva
0.650 0.350 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.648 0.352 0.000
T40.2 Other opioids
0.648 0.352 0.000
N03 Chronic nephritic syndrome
0.647 0.353 0.000
I77 Other disorders of arteries and arterioles
0.647 0.353 0.000
J00-J06 Acute upper respiratory infections
0.646 0.354 0.000
N02 Recurrent and persistent haematuria
0.645 0.355 0.000
J98 Other respiratory disorders
0.645 0.355 0.000
B34 Viral infection of unspecified site
0.644 0.356 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.644 0.356 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
I63.8 Other cerebral infarction
0.642 0.358 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.642 0.358 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.642 0.358 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.642 0.358 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.642 0.358 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.642 0.358 0.000
E20-E35 Disorders of other endocrine glands
0.642 0.358 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.642 0.358 0.000
S78 Traumatic amputation of hip and thigh
0.642 0.358 0.000
S77 Crushing injury of hip and thigh
0.642 0.358 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.642 0.358 0.000
S75 Injury of blood vessels at hip and thigh level
0.642 0.358 0.000
S74 Injury of nerves at hip and thigh level
0.642 0.358 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.642 0.358 0.000
S71 Open wound of hip and thigh
0.642 0.358 0.000
W22.8 Other specified place
0.640 0.359 0.000
W22.6 Industrial and construction area
0.640 0.359 0.000
W22.4 Street and highway
0.640 0.359 0.000
W22.0 Home
0.640 0.359 0.000
W22.7 Farm
0.640 0.359 0.000
W22.5 Trade and service area
0.640 0.359 0.000
W22.3 Sports and athletics area
0.640 0.359 0.000
W22.2 School, other institution and public administrative area
0.640 0.359 0.000
W22.1 Residential institution
0.640 0.359 0.000
N20.9 Urinary calculus, unspecified
0.639 0.360 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.639 0.361 0.000
I70 Atherosclerosis
0.639 0.361 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.639 0.361 0.000
I72 Other aneurysm
0.639 0.361 0.000
D00-D09 In situ neoplasms
0.639 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q80-Q89 Other congenital malformations
0.638 0.362 0.000
Q50-Q56 Congenital malformations of genital organs
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.638 0.362 0.000
E66 Obesity
0.638 0.362 0.000
N18.0 End-stage renal disease
0.636 0.364 0.000
M21.9 Acquired deformity of limb, unspecified
0.635 0.364 0.000
M21.8 Other specified acquired deformities of limbs
0.635 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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