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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117593677
log Bayes Factor = 14.7112
Chromosome 9   position 21,318,205  (GRCh37) Explore rs117593677 on Ensembl!
Variant rs117593677 is part of Cluster X0174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.992 0.008 0.000
I20 Angina pectoris
0.991 0.009 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.987 0.013 0.000
E11 Non-insulin-dependent diabetes mellitus
0.986 0.014 0.000
I45 Other conduction disorders
0.982 0.018 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.981 0.019 0.000
Z80 Family history of malignant neoplasm
0.980 0.020 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.975 0.025 0.000
I25.2 Old myocardial infarction
0.974 0.026 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.968 0.032 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.963 0.037 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.963 0.037 0.000
I20.9 Angina pectoris, unspecified
0.960 0.040 0.000
I45.1 Other and unspecified right bundle-branch block
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
Chapter VI Diseases of the nervous system
0.949 0.051 0.000
Z95.0 Presence of cardiac pacemaker
0.947 0.053 0.000
D60-D64 Aplastic and other anaemias
0.943 0.057 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.941 0.059 0.000
I20.0 Unstable angina
0.936 0.064 0.000
D69 Purpura and other haemorrhagic conditions
0.935 0.065 0.000
Z96 Presence of other functional implants
0.934 0.066 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.932 0.068 0.000
I22 Subsequent myocardial infarction
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.932 0.068 0.000
C34 Malignant neoplasm of bronchus and lung
0.931 0.069 0.000
E11.9 Without complications
0.930 0.070 0.000
O60-O75 Complications of labour and delivery
0.928 0.072 0.000
I25.1 Atherosclerotic heart disease
0.920 0.080 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.920 0.080 0.000
I44 Atrioventricular and left bundle-branch block
0.916 0.084 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.910 0.090 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.901 0.099 0.000
D64 Other anaemias
0.897 0.103 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.895 0.105 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.892 0.108 0.000
E11.2 With renal complications
0.890 0.110 0.000
I42 Cardiomyopathy
0.883 0.117 0.000
C60-C63 Malignant neoplasms of male genital organs
0.881 0.119 0.000
J95-J99 Other diseases of the respiratory system
0.879 0.121 0.000
I51 Complications and ill-defined descriptions of heart disease
0.877 0.123 0.000
T66-T78 Other and unspecified effects of external causes
0.876 0.124 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.873 0.127 0.000
O16 Unspecified maternal hypertension
0.873 0.127 0.000
Chapter XX External causes of morbidity and mortality
0.871 0.129 0.000
Z96.1 Presence of intraocular lens
0.871 0.129 0.000
J00-J06 Acute upper respiratory infections
0.871 0.129 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.871 0.129 0.000
S00-S09 Injuries to the head
0.868 0.132 0.000
E11.4 With neurological complications
0.867 0.133 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.866 0.134 0.000
D64.9 Anaemia, unspecified
0.865 0.135 0.000
I34 Nonrheumatic mitral valve disorders
0.863 0.137 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.862 0.138 0.000
I44.0 Atrioventricular block, first degree
0.862 0.138 0.000
Z96.0 Presence of urogenital implants
0.859 0.141 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.857 0.142 0.000
I21 Acute myocardial infarction
0.857 0.143 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.854 0.146 0.000
I46 Cardiac arrest
0.854 0.146 0.000
I05-I09 Chronic rheumatic heart diseases
0.853 0.147 0.000
O70 Perineal laceration during delivery
0.849 0.151 0.000
Z98 Other postsurgical states
0.848 0.152 0.000
J98 Other respiratory disorders
0.844 0.156 0.000
G90-G99 Other disorders of the nervous system
0.842 0.158 0.000
Chapter XXII Codes for special purposes
0.838 0.162 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.836 0.164 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.835 0.165 0.000
E40-E46 Malnutrition
0.834 0.166 0.000
G70-G73 Diseases of myoneural junction and muscle
0.834 0.166 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.834 0.166 0.000
S00 Superficial injury of head
0.829 0.171 0.000
C64-C68 Malignant neoplasms of urinary tract
0.827 0.173 0.000
S80-S89 Injuries to the knee and lower leg
0.826 0.174 0.000
D46 Myelodysplastic syndromes
0.825 0.175 0.000
I51.8 Other ill-defined heart diseases
0.825 0.175 0.000
Z89 Acquired absence of limb
0.824 0.176 0.000
S40-S49 Injuries to the shoulder and upper arm
0.823 0.177 0.000
O72 Postpartum haemorrhage
0.821 0.179 0.000
D69.6 Thrombocytopenia, unspecified
0.817 0.183 0.000
C34.0 Main bronchus
0.816 0.184 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
I50 Heart failure
0.810 0.190 0.000
I24 Other acute ischaemic heart diseases
0.810 0.190 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.808 0.192 0.000
I95 Hypotension
0.806 0.194 0.000
I45.6 Preexcitation syndrome
0.805 0.195 0.000
Z97 Presence of other devices
0.805 0.195 0.000
T78 Adverse effects, not elsewhere classified
0.804 0.196 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.804 0.196 0.000
J09-J18 Influenza and pneumonia
0.803 0.197 0.000
E14 Unspecified diabetes mellitus
0.803 0.197 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.801 0.199 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.801 0.199 0.000
Chapter VII Diseases of the eye and adnexa
0.799 0.201 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.799 0.201 0.000
E11.3 With ophthalmic complications
0.798 0.202 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.797 0.203 0.000
I46.9 Cardiac arrest, unspecified
0.797 0.203 0.000
I71 Aortic aneurysm and dissection
0.797 0.203 0.000
Z12 Special screening examination for neoplasms
0.797 0.203 0.000
E11.0 With coma
0.793 0.207 0.000
C34.9 Bronchus or lung, unspecified
0.791 0.209 0.000
I42.0 Dilated cardiomyopathy
0.789 0.211 0.000
E11.1 With ketoacidosis
0.785 0.215 0.000
I20.1 Angina pectoris with documented spasm
0.784 0.216 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.783 0.217 0.000
I45.5 Other specified heart block
0.782 0.218 0.000
I36 Nonrheumatic tricuspid valve disorders
0.782 0.218 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.780 0.220 0.000
E20-E35 Disorders of other endocrine glands
0.780 0.220 0.000
C34.1 Upper lobe, bronchus or lung
0.778 0.222 0.000
W00-W19 Falls
0.776 0.224 0.000
O85-O92 Complications predominantly related to the puerperium
0.776 0.224 0.000
S00.9 Superficial injury of head, part unspecified
0.775 0.225 0.000
C61 Malignant neoplasm of prostate
0.775 0.225 0.000
Z13 Special screening examination for other diseases and disorders
0.772 0.228 0.000
Z04 Examination and observation for other reasons
0.772 0.228 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.771 0.229 0.000
J98.4 Other disorders of lung
0.771 0.229 0.000
I08 Multiple valve diseases
0.769 0.231 0.000
J84 Other interstitial pulmonary diseases
0.766 0.234 0.000
Z95.2 Presence of prosthetic heart valve
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.764 0.236 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.762 0.238 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.761 0.239 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.761 0.239 0.000
Z94 Transplanted organ and tissue status
0.760 0.240 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.760 0.240 0.000
I30 Acute pericarditis
0.760 0.240 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.757 0.243 0.000
E10 Insulin-dependent diabetes mellitus
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
C34.3 Lower lobe, bronchus or lung
0.756 0.244 0.000
C32 Malignant neoplasm of larynx
0.756 0.244 0.000
D73 Diseases of spleen
0.755 0.245 0.000
O66 Other obstructed labour
0.754 0.246 0.000
E11.5 With peripheral circulatory complications
0.754 0.246 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.753 0.247 0.000
G70 Myasthenia gravis and other myoneural disorders
0.752 0.248 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.751 0.249 0.000
D75 Other diseases of blood and blood-forming organs
0.751 0.249 0.000
T78.4 Allergy, unspecified
0.747 0.253 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.746 0.254 0.000
O70.0 First degree perineal laceration during delivery
0.746 0.254 0.000
Z81 Family history of mental and behavioural disorders
0.745 0.255 0.000
I95.9 Hypotension, unspecified
0.744 0.256 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.742 0.258 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.742 0.258 0.000
D68 Other coagulation defects
0.741 0.258 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.739 0.261 0.000
I21.9 Acute myocardial infarction, unspecified
0.737 0.263 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.736 0.264 0.000
J03 Acute tonsillitis
0.735 0.265 0.000
D62 Acute posthaemorrhagic anaemia
0.734 0.266 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
I49 Other cardiac arrhythmias
0.734 0.266 0.000
G93 Other disorders of brain
0.733 0.267 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.731 0.269 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.730 0.270 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.727 0.273 0.000
G30-G32 Other degenerative diseases of the nervous system
0.726 0.274 0.000
C43 Malignant melanoma of skin
0.725 0.275 0.000
Z98.0 Intestinal bypass and anastomosis status
0.725 0.275 0.000
J02 Acute pharyngitis
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.723 0.277 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.723 0.277 0.000
Z57 Occupational exposure to risk-factors
0.723 0.277 0.000
Z29 Need for other prophylactic measures
0.722 0.278 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.721 0.279 0.000
E46 Unspecified protein-energy malnutrition
0.721 0.279 0.000
I44.1 Atrioventricular block, second degree
0.721 0.279 0.000
I34.1 Mitral (valve) prolapse
0.721 0.279 0.000
I99 Other and unspecified disorders of circulatory system
0.720 0.280 0.000
S60-S69 Injuries to the wrist and hand
0.720 0.280 0.000
D45 Polycythaemia vera
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I50.0 Congestive heart failure
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.284 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.714 0.286 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.711 0.289 0.000
O72.1 Other immediate postpartum haemorrhage
0.710 0.289 0.000
I51.0 Cardiac septal defect, acquired
0.710 0.290 0.000
W19 Unspecified fall
0.710 0.290 0.000
D61 Other aplastic anaemias
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.708 0.292 0.000
Z84 Family history of other conditions
0.707 0.293 0.000
E11.8 With unspecified complications
0.707 0.293 0.000
E11.7 With multiple complications
0.707 0.293 0.000
E11.6 With other specified complications
0.707 0.293 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.706 0.294 0.000
I45.9 Conduction disorder, unspecified
0.704 0.296 0.000
I45.8 Other specified conduction disorders
0.704 0.296 0.000
I45.4 Nonspecific intraventricular block
0.704 0.296 0.000
I45.3 Trifascicular block
0.704 0.296 0.000
I45.2 Bifascicular block
0.704 0.296 0.000
I45.0 Right fascicular block
0.704 0.296 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.702 0.298 0.000
Z80.6 Family history of leukaemia
0.702 0.298 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.702 0.298 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.702 0.298 0.000
S40 Superficial injury of shoulder and upper arm
0.702 0.298 0.000
I47 Paroxysmal tachycardia
0.701 0.299 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.701 0.299 0.000
Z03.4 Observation for suspected myocardial infarction
0.700 0.300 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.700 0.300 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.700 0.300 0.000
I42.8 Other cardiomyopathies
0.699 0.301 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.699 0.301 0.000
C92 Myeloid leukaemia
0.699 0.301 0.000
O61 Failed induction of labour
0.699 0.301 0.000
O63 Long labour
0.698 0.302 0.000
Z96.8 Presence of other specified functional implants
0.696 0.303 0.000
I33 Acute and subacute endocarditis
0.696 0.304 0.000
E14.9 Without complications
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.694 0.306 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.694 0.306 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.694 0.306 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.694 0.306 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.693 0.306 0.000
I34.0 Mitral (valve) insufficiency
0.693 0.307 0.000
G70.0 Myasthenia gravis
0.693 0.307 0.000
Z95.3 Presence of xenogenic heart valve
0.693 0.307 0.000
O62 Abnormalities of forces of labour
0.692 0.308 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.691 0.309 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.691 0.309 0.000
C31 Malignant neoplasm of accessory sinuses
0.691 0.309 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.691 0.309 0.000
C37 Malignant neoplasm of thymus
0.691 0.309 0.000
C33 Malignant neoplasm of trachea
0.691 0.309 0.000
D67 Hereditary factor IX deficiency
0.690 0.310 0.000
D66 Hereditary factor VIII deficiency
0.690 0.310 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.690 0.310 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.690 0.310 0.000
I24.8 Other forms of acute ischaemic heart disease
0.690 0.310 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.689 0.311 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.688 0.312 0.000
S00.8 Superficial injury of other parts of head
0.687 0.313 0.000
O70.1 Second degree perineal laceration during delivery
0.685 0.315 0.000
T68 Hypothermia
0.685 0.315 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
C62 Malignant neoplasm of testis
0.684 0.315 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
O00-O08 Pregnancy with abortive outcome
0.683 0.317 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.682 0.317 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.680 0.320 0.000
Z95.4 Presence of other heart-valve replacement
0.680 0.320 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.677 0.323 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.325 0.000
H30-H36 Disorders of choroid and retina
0.673 0.327 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.672 0.328 0.000
Z22 Carrier of infectious disease
0.672 0.328 0.000
D69.9 Haemorrhagic condition, unspecified
0.671 0.329 0.000
D69.8 Other specified haemorrhagic conditions
0.671 0.329 0.000
D69.5 Secondary thrombocytopenia
0.671 0.329 0.000
D69.4 Other primary thrombocytopenia
0.671 0.329 0.000
D69.2 Other nonthrombocytopenic purpura
0.671 0.329 0.000
D69.1 Qualitative platelet defects
0.671 0.329 0.000
D69.0 Allergic purpura
0.671 0.329 0.000
D73.0 Hyposplenism
0.670 0.330 0.000
Z98.1 Arthrodesis status
0.670 0.330 0.000
Z96.9 Presence of functional implant, unspecified
0.670 0.330 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.670 0.330 0.000
Z96.4 Presence of endocrine implants
0.670 0.330 0.000
Z96.3 Presence of artificial larynx
0.670 0.330 0.000
Z96.2 Presence of otological and audiological implants
0.670 0.330 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.668 0.332 0.000
Z10 Routine general health check-up of defined subpopulation
0.668 0.332 0.000
I22.8 Subsequent myocardial infarction of other sites
0.668 0.332 0.000
C67 Malignant neoplasm of bladder
0.667 0.333 0.000
C34.8 Overlapping lesion of bronchus and lung
0.667 0.333 0.000
C34.2 Middle lobe, bronchus or lung
0.667 0.333 0.000
E50-E64 Other nutritional deficiencies
0.667 0.333 0.000
Z01.8 Other specified special examinations
0.666 0.334 0.000
S06 Intracranial injury
0.666 0.334 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.665 0.335 0.000
O74 Complications of anaesthesia during labour and delivery
0.665 0.335 0.000
O73 Retained placenta and membranes, without haemorrhage
0.665 0.335 0.000
O71 Other obstetric trauma
0.665 0.335 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.665 0.335 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.665 0.335 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.665 0.335 0.000
O60 Preterm delivery
0.665 0.335 0.000
Z83 Family history of other specific disorders
0.665 0.335 0.000
C77.1 Intrathoracic lymph nodes
0.664 0.336 0.000
Z03.1 Observation for suspected malignant neoplasm
0.663 0.337 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.662 0.338 0.000
Z13.9 Special screening examination, unspecified
0.662 0.338 0.000
J98.1 Pulmonary collapse
0.660 0.340 0.000
O15 Eclampsia
0.659 0.340 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.659 0.340 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.659 0.340 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.659 0.340 0.000
G40-G47 Episodic and paroxysmal disorders
0.659 0.341 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.659 0.341 0.000
W19.9 Unspecified place
0.659 0.341 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.658 0.342 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.658 0.342 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.658 0.342 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.657 0.343 0.000
D47.1 Chronic myeloproliferative disease
0.657 0.343 0.000
I44.6 Other and unspecified fascicular block
0.657 0.343 0.000
I44.5 Left posterior fascicular block
0.657 0.343 0.000
I44.4 Left anterior fascicular block
0.657 0.343 0.000
I44.3 Other and unspecified atrioventricular block
0.657 0.343 0.000
S89 Other and unspecified injuries of lower leg
0.656 0.343 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.656 0.344 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.655 0.345 0.000
D41.4 Bladder
0.655 0.345 0.000
Z04.8 Examination and observation for other specified reasons
0.654 0.346 0.000
T79-T79 Certain early complications of trauma
0.654 0.346 0.000
O70.2 Third degree perineal laceration during delivery
0.654 0.346 0.000
S81 Open wound of lower leg
0.653 0.347 0.000
Z01.6 Radiological examination, not elsewhere classified
0.653 0.347 0.000
D80-D89 Certain disorders involving the immune mechanism
0.652 0.348 0.000
Z97.4 Presence of external hearing-aid
0.652 0.348 0.000
I77 Other disorders of arteries and arterioles
0.651 0.349 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
Z03.3 Observation for suspected nervous system disorder
0.651 0.349 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.650 0.350 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.650 0.350 0.000
Z89.6 Acquired absence of leg above knee
0.649 0.351 0.000
I38 Endocarditis, valve unspecified
0.647 0.353 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.647 0.353 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.647 0.353 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.647 0.353 0.000
D44.3 Pituitary gland
0.646 0.354 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.645 0.355 0.000
D64.8 Other specified anaemias
0.643 0.356 0.000
D64.4 Congenital dyserythropoietic anaemia
0.643 0.356 0.000
D64.3 Other sideroblastic anaemias
0.643 0.356 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.643 0.356 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.643 0.356 0.000
D64.0 Hereditary sideroblastic anaemia
0.643 0.356 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.642 0.358 0.000
D75.1 Secondary polycythaemia
0.642 0.358 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.641 0.358 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.641 0.359 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.641 0.359 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.641 0.359 0.000
J00 Acute nasopharyngitis [common cold]
0.641 0.359 0.000
Z01.7 Laboratory examination
0.640 0.359 0.000
E23 Hypofunction and other disorders of pituitary gland
0.640 0.360 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.639 0.360 0.000
I49.8 Other specified cardiac arrhythmias
0.639 0.361 0.000
J03.9 Acute tonsillitis, unspecified
0.637 0.363 0.000
Z96.7 Presence of other bone and tendon implants
0.636 0.364 0.000
Z89.5 Acquired absence of leg at or below knee
0.636 0.364 0.000
G58 Other mononeuropathies
0.635 0.365 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.634 0.366 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.633 0.367 0.000
I42.6 Alcoholic cardiomyopathy
0.633 0.367 0.000
I42.5 Other restrictive cardiomyopathy
0.633 0.367 0.000
I42.4 Endocardial fibroelastosis
0.633 0.367 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.633 0.367 0.000
I42.2 Other hypertrophic cardiomyopathy
0.633 0.367 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.633 0.367 0.000
Z89.4 Acquired absence of foot and ankle
0.633 0.367 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.632 0.368 0.000
C60 Malignant neoplasm of penis
0.632 0.368 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.632 0.368 0.000
Z94.8 Other transplanted organ and tissue status
0.631 0.369 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.631 0.369 0.000
J96 Respiratory failure, not elsewhere classified
0.631 0.369 0.000
J06.9 Acute upper respiratory infection, unspecified
0.630 0.370 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.630 0.370 0.000
I70 Atherosclerosis
0.629 0.371 0.000
I51.6 Cardiovascular disease, unspecified
0.629 0.371 0.000
I51.5 Myocardial degeneration
0.629 0.371 0.000
I51.4 Myocarditis, unspecified
0.629 0.371 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.629 0.371 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.629 0.371 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.629 0.371 0.000
Z57.2 Occupational exposure to dust
0.629 0.371 0.000
O86 Other puerperal infections
0.629 0.371 0.000
S02 Fracture of skull and facial bones
0.628 0.371 0.000
T75 Effects of other external causes
0.628 0.371 0.000
T74 Maltreatment syndromes
0.628 0.371 0.000
T73 Effects of other deprivation
0.628 0.371 0.000
T70 Effects of air pressure and water pressure
0.628 0.371 0.000
T69 Other effects of reduced temperature
0.628 0.371 0.000
T67 Effects of heat and light
0.628 0.371 0.000
T71 Asphyxiation
0.628 0.371 0.000
T66 Unspecified effects of radiation
0.628 0.371 0.000
J18 Pneumonia, organism unspecified
0.628 0.372 0.000
G93.6 Cerebral oedema
0.627 0.373 0.000
Z04.1 Examination and observation following transport accident
0.626 0.374 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.626 0.374 0.000
D74 Methaemoglobinaemia
0.626 0.374 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.626 0.374 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.626 0.374 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.626 0.374 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.625 0.374 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.625 0.375 0.000
U80 Agent resistant to penicillin and related antibiotics
0.625 0.375 0.000
E10.5 With peripheral circulatory complications
0.625 0.375 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.625 0.375 0.000
Y35-Y36 Legal intervention and operations of war
0.625 0.375 0.000
Y10-Y34 Event of undetermined intent
0.625 0.375 0.000
Y00-Y09 Assault
0.625 0.375 0.000
X85-X99 Assault
0.625 0.375 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.625 0.375 0.000
X50-X57 Overexertion, travel and privation
0.625 0.375 0.000
X30-X39 Exposure to forces of nature
0.625 0.375 0.000
X20-X29 Contact with venomous animals and plants
0.625 0.375 0.000
X10-X19 Contact with heat and hot substances
0.625 0.375 0.000
X00-X09 Exposure to smoke, fire and flames
0.625 0.375 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.625 0.375 0.000
W75-W84 Other accidental threats to breathing
0.625 0.375 0.000
W65-W74 Accidental drowning and submersion
0.625 0.375 0.000
W50-W64 Exposure to animate mechanical forces
0.625 0.375 0.000
V98-V99 Other and unspecified transport accidents
0.625 0.375 0.000
V95-V97 Air and space transport accidents
0.625 0.375 0.000
V90-V94 Water transport accidents
0.625 0.375 0.000
V80-V89 Other land transport accidents
0.625 0.375 0.000
V70-V79 Bus occupant injured in transport accident
0.625 0.375 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.625 0.375 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.625 0.375 0.000
V40-V49 Car occupant injured in transport accident
0.625 0.375 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.625 0.375 0.000
V01-V09 Pedestrian injured in transport accident
0.625 0.375 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.624 0.375 0.000
J04 Acute laryngitis and tracheitis
0.624 0.375 0.000
J01 Acute sinusitis
0.624 0.375 0.000
J10 Influenza due to identified influenza virus
0.623 0.377 0.000
I74 Arterial embolism and thrombosis
0.623 0.377 0.000
D00-D09 In situ neoplasms
0.623 0.377 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.622 0.377 0.000
S08 Traumatic amputation of part of head
0.622 0.378 0.000
S07 Crushing injury of head
0.622 0.378 0.000
S05 Injury of eye and orbit
0.622 0.378 0.000
S04 Injury of cranial nerves
0.622 0.378 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.622 0.378 0.000
I10-I15 Hypertensive diseases
0.622 0.378 0.000
T78.2 Anaphylactic shock, unspecified
0.621 0.378 0.000
S00.3 Superficial injury of nose
0.621 0.378 0.000
S20-S29 Injuries to the thorax
0.621 0.379 0.000
Z97.8 Presence of other specified devices
0.621 0.379 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.621 0.379 0.000
C95 Leukaemia of unspecified cell type
0.621 0.379 0.000
C94 Other leukaemias of specified cell type
0.621 0.379 0.000
C93 Monocytic leukaemia
0.621 0.379 0.000
C88 Malignant immunoproliferative diseases
0.621 0.379 0.000
C86 Other specified types of T/NK-cell lymphoma
0.621 0.379 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.621 0.379 0.000
C81 Hodgkin's disease
0.621 0.379 0.000
S00.1 Contusion of eyelid and periocular area
0.620 0.380 0.000
J02.9 Acute pharyngitis, unspecified
0.619 0.381 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.618 0.381 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.618 0.381 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.618 0.381 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.617 0.382 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.617 0.383 0.000
Z29.2 Other prophylactic chemotherapy
0.617 0.383 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.616 0.383 0.000
I44.2 Atrioventricular block, complete
0.616 0.384 0.000
S90-S99 Injuries to the ankle and foot
0.616 0.384 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.616 0.384 0.000
J20-J22 Other acute lower respiratory infections
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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