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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12077060
log Bayes Factor = 11.4093
Chromosome 1   position 97,453,507  (GRCh37) Explore rs12077060 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
I34 Nonrheumatic mitral valve disorders
0.986 0.014 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.982 0.018 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.981 0.019 0.000
H90-H95 Other disorders of ear
0.979 0.021 0.000
I50 Heart failure
0.979 0.021 0.000
H65-H75 Diseases of middle ear and mastoid
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.969 0.031 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.968 0.032 0.000
E10-E14 Diabetes mellitus
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
I34.0 Mitral (valve) insufficiency
0.953 0.047 0.000
I51 Complications and ill-defined descriptions of heart disease
0.949 0.051 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.945 0.055 0.000
I44 Atrioventricular and left bundle-branch block
0.943 0.057 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.942 0.058 0.000
C79 Secondary malignant neoplasm of other sites
0.942 0.058 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
I50.1 Left ventricular failure
0.938 0.062 0.000
H60-H62 Diseases of external ear
0.935 0.065 0.000
Y52 Agents primarily affecting the cardiovascular system
0.935 0.065 0.000
D00-D09 In situ neoplasms
0.931 0.069 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.930 0.070 0.000
Chapter XIV Diseases of the genitourinary system
0.922 0.078 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.920 0.080 0.000
E10 Insulin-dependent diabetes mellitus
0.919 0.081 0.000
N40-N51 Diseases of male genital organs
0.916 0.084 0.000
I34.1 Mitral (valve) prolapse
0.914 0.086 0.000
S10-S19 Injuries to the neck
0.914 0.086 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.913 0.087 0.000
C64-C68 Malignant neoplasms of urinary tract
0.910 0.090 0.000
H93 Other disorders of ear, not elsewhere classified
0.909 0.091 0.000
I35 Nonrheumatic aortic valve disorders
0.908 0.092 0.000
I51.8 Other ill-defined heart diseases
0.907 0.093 0.000
H91 Other hearing loss
0.903 0.097 0.000
C78.0 Secondary malignant neoplasm of lung
0.899 0.101 0.000
N50 Other disorders of male genital organs
0.897 0.103 0.000
S00-S09 Injuries to the head
0.897 0.103 0.000
N25-N29 Other disorders of kidney and ureter
0.892 0.108 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.891 0.109 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.888 0.112 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.885 0.115 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.885 0.115 0.000
E10.9 Without complications
0.883 0.117 0.000
I31 Other diseases of pericardium
0.883 0.117 0.000
I50.0 Congestive heart failure
0.881 0.119 0.000
I05-I09 Chronic rheumatic heart diseases
0.880 0.120 0.000
H71 Cholesteatoma of middle ear
0.880 0.120 0.000
G57 Mononeuropathies of lower limb
0.878 0.122 0.000
N50.8 Other specified disorders of male genital organs
0.878 0.122 0.000
S20-S29 Injuries to the thorax
0.873 0.127 0.000
Chapter I Certain infectious and parasitic diseases
0.871 0.129 0.000
G90-G99 Other disorders of the nervous system
0.870 0.130 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.870 0.130 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.869 0.130 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.869 0.131 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.868 0.132 0.000
S90-S99 Injuries to the ankle and foot
0.868 0.132 0.000
E14 Unspecified diabetes mellitus
0.867 0.133 0.000
H61 Other disorders of external ear
0.866 0.134 0.000
T92 Sequelae of injuries of upper limb
0.866 0.134 0.000
N42 Other disorders of prostate
0.866 0.134 0.000
I44.7 Left bundle-branch block, unspecified
0.860 0.140 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.860 0.140 0.000
H93.1 Tinnitus
0.858 0.142 0.000
C79.2 Secondary malignant neoplasm of skin
0.855 0.145 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.854 0.146 0.000
G57.6 Lesion of plantar nerve
0.854 0.146 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.853 0.147 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.851 0.149 0.000
H91.9 Hearing loss, unspecified
0.848 0.152 0.000
C15-C26 Malignant neoplasms of digestive organs
0.847 0.153 0.000
E20-E35 Disorders of other endocrine glands
0.845 0.155 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.840 0.160 0.000
H74 Other disorders of middle ear and mastoid
0.838 0.162 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.838 0.162 0.000
D24 Benign neoplasm of breast
0.837 0.163 0.000
D10-D36 Benign neoplasms
0.836 0.164 0.000
H65 Nonsuppurative otitis media
0.836 0.164 0.000
G95 Other diseases of spinal cord
0.835 0.165 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.834 0.166 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.831 0.168 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.830 0.170 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.829 0.171 0.000
H80-H83 Diseases of inner ear
0.829 0.171 0.000
D37.7 Other digestive organs
0.825 0.175 0.000
S00 Superficial injury of head
0.821 0.179 0.000
N48 Other disorders of penis
0.820 0.180 0.000
E40-E46 Malnutrition
0.813 0.187 0.000
Q60-Q64 Congenital malformations of the urinary system
0.813 0.187 0.000
Y83.8 Other surgical procedures
0.813 0.187 0.000
T91 Sequelae of injuries of neck and trunk
0.813 0.187 0.000
H69 Other disorders of Eustachian tube
0.811 0.189 0.000
D06 Carcinoma in situ of cervix uteri
0.810 0.190 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.810 0.190 0.000
C78.7 Secondary malignant neoplasm of liver
0.810 0.190 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.806 0.194 0.000
T66-T78 Other and unspecified effects of external causes
0.805 0.195 0.000
N10-N16 Renal tubulo-interstitial diseases
0.805 0.195 0.000
C88 Malignant immunoproliferative diseases
0.802 0.198 0.000
S05 Injury of eye and orbit
0.801 0.199 0.000
E00-E07 Disorders of thyroid gland
0.800 0.200 0.000
G83 Other paralytic syndromes
0.799 0.201 0.000
S50-S59 Injuries to the elbow and forearm
0.798 0.202 0.000
H61.2 Impacted cerumen
0.794 0.206 0.000
C92 Myeloid leukaemia
0.793 0.207 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.793 0.207 0.000
C83.3 Large cell (diffuse)
0.792 0.208 0.000
N42.8 Other specified disorders of prostate
0.790 0.210 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.788 0.212 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.787 0.213 0.000
T92.1 Sequelae of fracture of arm
0.787 0.213 0.000
H90 Conductive and sensorineural hearing loss
0.786 0.214 0.000
E14.3 With ophthalmic complications
0.784 0.216 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.784 0.216 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.783 0.217 0.000
G30-G32 Other degenerative diseases of the nervous system
0.783 0.217 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.783 0.217 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.781 0.219 0.000
I31.9 Disease of pericardium, unspecified
0.780 0.220 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.779 0.220 0.000
Y95 Nosocomial condition
0.778 0.222 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.778 0.222 0.000
Y83.4 Other reconstructive surgery
0.777 0.223 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.776 0.224 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.776 0.224 0.000
G95.8 Other specified diseases of spinal cord
0.776 0.224 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.776 0.224 0.000
N20-N23 Urolithiasis
0.774 0.226 0.000
S20 Superficial injury of thorax
0.771 0.229 0.000
Y43 Primarily systemic agents
0.771 0.229 0.000
Y52.1 Calcium-channel blockers
0.770 0.230 0.000
T79-T79 Certain early complications of trauma
0.770 0.230 0.000
S60-S69 Injuries to the wrist and hand
0.769 0.231 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.769 0.231 0.000
S13.4 Sprain and strain of cervical spine
0.768 0.232 0.000
Y57 Other and unspecified drugs and medicaments
0.768 0.232 0.000
I05 Rheumatic mitral valve diseases
0.768 0.232 0.000
I35.9 Aortic valve disorder, unspecified
0.768 0.232 0.000
N48.4 Impotence of organic origin
0.767 0.233 0.000
Q50-Q56 Congenital malformations of genital organs
0.766 0.234 0.000
H73 Other disorders of tympanic membrane
0.764 0.236 0.000
E10.3 With ophthalmic complications
0.764 0.236 0.000
S00.8 Superficial injury of other parts of head
0.763 0.237 0.000
I47 Paroxysmal tachycardia
0.762 0.238 0.000
N43 Hydrocele and spermatocele
0.762 0.238 0.000
G58 Other mononeuropathies
0.761 0.239 0.000
I38 Endocarditis, valve unspecified
0.761 0.239 0.000
S40-S49 Injuries to the shoulder and upper arm
0.761 0.239 0.000
W00-W19 Falls
0.759 0.240 0.000
H60 Otitis externa
0.757 0.243 0.000
D37.4 Colon
0.757 0.243 0.000
C85.1 B-cell lymphoma, unspecified
0.756 0.244 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.754 0.246 0.000
I35.1 Aortic (valve) insufficiency
0.754 0.246 0.000
N50.9 Disorder of male genital organs, unspecified
0.753 0.247 0.000
H61.3 Acquired stenosis of external ear canal
0.752 0.248 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.751 0.249 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.750 0.250 0.000
S27 Injury of other and unspecified intrathoracic organs
0.749 0.251 0.000
I44.6 Other and unspecified fascicular block
0.749 0.251 0.000
G51 Facial nerve disorders
0.747 0.253 0.000
G95.9 Disease of spinal cord, unspecified
0.745 0.255 0.000
N28.8 Other specified disorders of kidney and ureter
0.745 0.255 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.744 0.256 0.000
C18 Malignant neoplasm of colon
0.743 0.257 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.740 0.259 0.000
I44.1 Atrioventricular block, second degree
0.739 0.261 0.000
T93 Sequelae of injuries of lower limb
0.738 0.262 0.000
D09 Carcinoma in situ of other and unspecified sites
0.738 0.262 0.000
S12 Fracture of neck
0.737 0.263 0.000
I44.2 Atrioventricular block, complete
0.737 0.263 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.737 0.263 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.737 0.263 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.734 0.266 0.000
S92 Fracture of foot, except ankle
0.734 0.266 0.000
I51.6 Cardiovascular disease, unspecified
0.734 0.266 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.734 0.266 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.733 0.267 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
E10.8 With unspecified complications
0.731 0.269 0.000
I08 Multiple valve diseases
0.727 0.273 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.727 0.273 0.000
I50.9 Heart failure, unspecified
0.727 0.273 0.000
D06.9 Cervix, unspecified
0.724 0.276 0.000
D03 Melanoma in situ
0.722 0.278 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
N27 Small kidney of unknown cause
0.720 0.280 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.720 0.280 0.000
I36 Nonrheumatic tricuspid valve disorders
0.719 0.281 0.000
C25 Malignant neoplasm of pancreas
0.719 0.281 0.000
D32 Benign neoplasm of meninges
0.718 0.282 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.717 0.283 0.000
T98 Sequelae of other and unspecified effects of external causes
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
D37.9 Digestive organ, unspecified
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
G82 Paraplegia and tetraplegia
0.713 0.287 0.000
Y83.9 Surgical procedure, unspecified
0.712 0.288 0.000
I35.8 Other aortic valve disorders
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.711 0.289 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
A30-A49 Other bacterial diseases
0.710 0.290 0.000
N42.2 Atrophy of prostate
0.708 0.292 0.000
C67 Malignant neoplasm of bladder
0.708 0.292 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.707 0.293 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.707 0.293 0.000
G57.3 Lesion of lateral popliteal nerve
0.706 0.294 0.000
C15 Malignant neoplasm of oesophagus
0.705 0.295 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
C95 Leukaemia of unspecified cell type
0.704 0.296 0.000
C94 Other leukaemias of specified cell type
0.704 0.296 0.000
C93 Monocytic leukaemia
0.704 0.296 0.000
C86 Other specified types of T/NK-cell lymphoma
0.704 0.296 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.704 0.296 0.000
C81 Hodgkin's disease
0.704 0.296 0.000
Q24 Other congenital malformations of heart
0.704 0.296 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.703 0.297 0.000
I30 Acute pericarditis
0.703 0.297 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.702 0.298 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.702 0.298 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
D07.5 Prostate
0.701 0.299 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.699 0.301 0.000
H70 Mastoiditis and related conditions
0.699 0.301 0.000
H68 Eustachian salpingitis and obstruction
0.699 0.301 0.000
H67 Otitis media in diseases classified elsewhere
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
N20 Calculus of kidney and ureter
0.698 0.302 0.000
C32 Malignant neoplasm of larynx
0.698 0.302 0.000
C45 Mesothelioma
0.697 0.303 0.000
E13 Other specified diabetes mellitus
0.697 0.303 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.696 0.304 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.695 0.305 0.000
D04 Carcinoma in situ of skin
0.695 0.305 0.000
Y59 Other and unspecified vaccines and biological substances
0.694 0.305 0.000
Y58 Bacterial vaccines
0.694 0.305 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.305 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.305 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.694 0.305 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.694 0.305 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.694 0.305 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.305 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.694 0.305 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.694 0.305 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
G83.4 Cauda equina syndrome
0.693 0.307 0.000
E23 Hypofunction and other disorders of pituitary gland
0.693 0.307 0.000
E46 Unspecified protein-energy malnutrition
0.693 0.307 0.000
S70-S79 Injuries to the hip and thigh
0.693 0.307 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
G83.1 Monoplegia of lower limb
0.692 0.308 0.000
T92.0 Sequelae of open wound of upper limb
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
N48.0 Leukoplakia of penis
0.691 0.309 0.000
C83.1 Small cleaved cell (diffuse)
0.691 0.309 0.000
S05.1 Contusion of eyeball and orbital tissues
0.690 0.310 0.000
C92.1 Chronic myeloid leukaemia
0.689 0.311 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.689 0.311 0.000
E10.2 With renal complications
0.688 0.312 0.000
E12 Malnutrition-related diabetes mellitus
0.687 0.313 0.000
S06 Intracranial injury
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.683 0.317 0.000
N28.1 Cyst of kidney, acquired
0.683 0.317 0.000
E50-E64 Other nutritional deficiencies
0.683 0.317 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.682 0.318 0.000
I31.3 Pericardial effusion (noninflammatory)
0.682 0.318 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.682 0.318 0.000
I51.5 Myocardial degeneration
0.680 0.320 0.000
I51.4 Myocarditis, unspecified
0.680 0.320 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.680 0.320 0.000
I51.0 Cardiac septal defect, acquired
0.680 0.320 0.000
G54 Nerve root and plexus disorders
0.679 0.321 0.000
T91.3 Sequelae of injury of spinal cord
0.678 0.322 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.678 0.322 0.000
I33 Acute and subacute endocarditis
0.678 0.322 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
I44.3 Other and unspecified atrioventricular block
0.677 0.323 0.000
H65.3 Chronic mucoid otitis media
0.677 0.323 0.000
S10 Superficial injury of neck
0.676 0.323 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
I44.5 Left posterior fascicular block
0.676 0.324 0.000
I44.4 Left anterior fascicular block
0.676 0.324 0.000
E14.9 Without complications
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.676 0.324 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.676 0.324 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.676 0.324 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.675 0.325 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.675 0.325 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.674 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.674 0.325 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.674 0.325 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.325 0.000
H81 Disorders of vestibular function
0.673 0.327 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.672 0.328 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.670 0.330 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.670 0.330 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.670 0.330 0.000
Y52.7 Peripheral vasodilators
0.670 0.330 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.670 0.330 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.670 0.330 0.000
S91 Open wound of ankle and foot
0.670 0.330 0.000
Chapter XI Diseases of the digestive system
0.669 0.331 0.000
T78 Adverse effects, not elsewhere classified
0.669 0.331 0.000
C18.1 Appendix
0.668 0.332 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.668 0.332 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.668 0.332 0.000
S00.5 Superficial injury of lip and oral cavity
0.668 0.332 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.667 0.333 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.667 0.333 0.000
C85.0 Lymphosarcoma
0.667 0.333 0.000
E27 Other disorders of adrenal gland
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.665 0.335 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.665 0.335 0.000
I35.0 Aortic (valve) stenosis
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
S60 Superficial injury of wrist and hand
0.663 0.337 0.000
D48.7 Other specified sites
0.663 0.337 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.663 0.337 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.662 0.338 0.000
N42.0 Calculus of prostate
0.661 0.339 0.000
I45 Other conduction disorders
0.659 0.341 0.000
E05.9 Thyrotoxicosis, unspecified
0.659 0.341 0.000
D16 Benign neoplasm of bone and articular cartilage
0.659 0.341 0.000
E10.7 With multiple complications
0.659 0.341 0.000
E10.6 With other specified complications
0.659 0.341 0.000
E10.5 With peripheral circulatory complications
0.659 0.341 0.000
E10.0 With coma
0.659 0.341 0.000
C17 Malignant neoplasm of small intestine
0.658 0.341 0.000
E26 Hyperaldosteronism
0.657 0.342 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.657 0.343 0.000
N46 Male infertility
0.657 0.343 0.000
N44 Torsion of testis
0.657 0.343 0.000
N42.9 Disorder of prostate, unspecified
0.656 0.344 0.000
S17 Crushing injury of neck
0.655 0.345 0.000
S15 Injury of blood vessels at neck level
0.655 0.345 0.000
S14 Injury of nerves and spinal cord at neck level
0.655 0.345 0.000
S11 Open wound of neck
0.655 0.345 0.000
S18 Traumatic amputation at neck level
0.655 0.345 0.000
S16 Injury of muscle and tendon at neck level
0.655 0.345 0.000
N10 Acute tubulo-interstitial nephritis
0.655 0.345 0.000
S27.2 Traumatic heamopneumothorax
0.655 0.345 0.000
G52 Disorders of other cranial nerves
0.655 0.345 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.655 0.345 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.654 0.346 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.653 0.347 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.652 0.348 0.000
C65 Malignant neoplasm of renal pelvis
0.652 0.348 0.000
K70-K77 Diseases of liver
0.652 0.348 0.000
H93.9 Disorder of ear, unspecified
0.652 0.348 0.000
H93.8 Other specified disorders of ear
0.652 0.348 0.000
H93.3 Disorders of acoustic nerve
0.652 0.348 0.000
H93.2 Other abnormal auditory perceptions
0.652 0.348 0.000
H93.0 Degenerative and vascular disorders of ear
0.652 0.348 0.000
I05.0 Mitral stenosis
0.651 0.349 0.000
N43.3 Hydrocele, unspecified
0.651 0.349 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.651 0.349 0.000
I47.1 Supraventricular tachycardia
0.650 0.350 0.000
D11 Benign neoplasm of major salivary glands
0.650 0.350 0.000
N45 Orchitis and epididymitis
0.650 0.350 0.000
H69.8 Other specified disorders of Eustachian tube
0.649 0.351 0.000
D32.0 Cerebral meninges
0.649 0.351 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.649 0.351 0.000
Q80-Q89 Other congenital malformations
0.648 0.351 0.000
S50 Superficial injury of forearm
0.648 0.352 0.000
H91.8 Other specified hearing loss
0.647 0.353 0.000
H91.3 Deaf mutism, not elsewhere classified
0.647 0.353 0.000
H91.2 Sudden idiopathic hearing loss
0.647 0.353 0.000
H91.1 Presbycusis
0.647 0.353 0.000
H91.0 Ototoxic hearing loss
0.647 0.353 0.000
C79.6 Secondary malignant neoplasm of ovary
0.647 0.353 0.000
G70-G73 Diseases of myoneural junction and muscle
0.647 0.353 0.000
Y42.5 Other oestrogens and progestogens
0.646 0.354 0.000
N41 Inflammatory diseases of prostate
0.646 0.354 0.000
S68 Traumatic amputation of wrist and hand
0.646 0.354 0.000
B15-B19 Viral hepatitis
0.645 0.354 0.000
H90.2 Conductive hearing loss, unspecified
0.645 0.355 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.645 0.355 0.000
H65.4 Other chronic nonsuppurative otitis media
0.645 0.355 0.000
S00.3 Superficial injury of nose
0.645 0.355 0.000
K83 Other diseases of biliary tract
0.645 0.355 0.000
D37.0 Lip, oral cavity and pharynx
0.645 0.355 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.644 0.356 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.644 0.356 0.000
S99 Other and unspecified injuries of ankle and foot
0.644 0.356 0.000
H69.9 Eustachian tube disorder, unspecified
0.644 0.356 0.000
N50.0 Atrophy of testis
0.643 0.357 0.000
H80 Otosclerosis
0.643 0.357 0.000
S08 Traumatic amputation of part of head
0.643 0.357 0.000
S07 Crushing injury of head
0.643 0.357 0.000
S04 Injury of cranial nerves
0.643 0.357 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.643 0.357 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.643 0.357 0.000
I44.0 Atrioventricular block, first degree
0.643 0.357 0.000
S00.7 Multiple superficial injuries of head
0.641 0.358 0.000
E16 Other disorders of pancreatic internal secretion
0.641 0.359 0.000
C66 Malignant neoplasm of ureter
0.641 0.359 0.000
C34 Malignant neoplasm of bronchus and lung
0.640 0.360 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.639 0.361 0.000
N25 Disorders resulting from impaired renal tubular function
0.639 0.361 0.000
N26 Unspecified contracted kidney
0.639 0.361 0.000
D37.6 Liver, gallbladder and bile ducts
0.639 0.361 0.000
D37.3 Appendix
0.639 0.361 0.000
D37.2 Small intestine
0.639 0.361 0.000
D37.1 Stomach
0.639 0.361 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.638 0.362 0.000
E24 Cushing's syndrome
0.638 0.362 0.000
C23 Malignant neoplasm of gallbladder
0.638 0.362 0.000
D10 Benign neoplasm of mouth and pharynx
0.637 0.363 0.000
Y43.1 Antineoplastic antimetabolites
0.637 0.363 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.636 0.364 0.000
S51 Open wound of forearm
0.636 0.364 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.635 0.365 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.635 0.365 0.000
C83.7 Burkitt's tumour
0.635 0.365 0.000
C83.6 Undifferentiated (diffuse)
0.635 0.365 0.000
C83.5 Lymphoblastic (diffuse)
0.635 0.365 0.000
C83.4 Immunoblastic (diffuse)
0.635 0.365 0.000
C83.2 Mixed small and large cell (diffuse)
0.635 0.365 0.000
H92 Otalgia and effusion of ear
0.633 0.366 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.633 0.367 0.000
G96 Other disorders of central nervous system
0.633 0.367 0.000
I31.8 Other specified diseases of pericardium
0.633 0.367 0.000
I31.2 Haemopericardium, not elsewhere classified
0.633 0.367 0.000
I31.1 Chronic constrictive pericarditis
0.633 0.367 0.000
I31.0 Chronic adhesive pericarditis
0.633 0.367 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.632 0.368 0.000
D29 Benign neoplasm of male genital organs
0.632 0.368 0.000
A00-A09 Intestinal infectious diseases
0.632 0.368 0.000
I09 Other rheumatic heart diseases
0.631 0.369 0.000
I06 Rheumatic aortic valve diseases
0.631 0.369 0.000
Q24.8 Other specified congenital malformations of heart
0.631 0.369 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.631 0.369 0.000
I10-I15 Hypertensive diseases
0.631 0.369 0.000
D46 Myelodysplastic syndromes
0.630 0.370 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.630 0.370 0.000
G57.5 Tarsal tunnel syndrome
0.630 0.370 0.000
G57.4 Lesion of medial popliteal nerve
0.630 0.370 0.000
G57.2 Lesion of femoral nerve
0.630 0.370 0.000
G57.1 Meralgia paraesthetica
0.630 0.370 0.000
G57.0 Lesion of sciatic nerve
0.630 0.370 0.000
N13 Obstructive and reflux uropathy
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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