TreeWAS – Variant ID: rs17776284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
F30-F39 Mood [affective] disorders	0.999	0.001
F32 Depressive episode	0.998	0.002
F32.9 Depressive episode, unspecified	0.998	0.002
Chapter II Neoplasms	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
C15-C26 Malignant neoplasms of digestive organs	0.992	0.008
H65-H75 Diseases of middle ear and mastoid	0.989	0.011
H90-H95 Other disorders of ear	0.989	0.011
E10-E14 Diabetes mellitus	0.988	0.012
S40-S49 Injuries to the shoulder and upper arm	0.987	0.013
E10 Insulin-dependent diabetes mellitus	0.985	0.015
T36-T50 Poisoning by drugs, medicaments and biological substances	0.980	0.020
S00-S09 Injuries to the head	0.980	0.020
C51-C58 Malignant neoplasms of female genital organs	0.978	0.022
E10.9 Without complications	0.978	0.022
C25 Malignant neoplasm of pancreas	0.971	0.029
S42 Fracture of shoulder and upper arm	0.962	0.038
F40-F48 Neurotic, stress-related and somatoform disorders	0.961	0.039
H72 Perforation of tympanic membrane	0.955	0.045
C54 Malignant neoplasm of corpus uteri	0.954	0.046
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.949	0.051
H91 Other hearing loss	0.945	0.055
Chapter VI Diseases of the nervous system	0.944	0.056
C54.1 Endometrium	0.936	0.064
E20-E35 Disorders of other endocrine glands	0.933	0.067
S06 Intracranial injury	0.931	0.069
H90 Conductive and sensorineural hearing loss	0.928	0.072
Chapter I Certain infectious and parasitic diseases	0.925	0.075
D37-D48 Neoplasms of uncertain or unknown behaviour	0.920	0.080
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.917	0.083
F41 Other anxiety disorders	0.914	0.086
H72.9 Perforation of tympanic membrane, unspecified	0.913	0.087
C25.0 Head of pancreas	0.905	0.095
H91.9 Hearing loss, unspecified	0.899	0.101
E00-E07 Disorders of thyroid gland	0.898	0.102
T66-T78 Other and unspecified effects of external causes	0.895	0.105
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.890	0.110
S42.0 Fracture of clavicle	0.886	0.114
F60-F69 Disorders of adult personality and behaviour	0.885	0.115
C21 Malignant neoplasm of anus and anal canal	0.882	0.118
S01 Open wound of head	0.880	0.120
C25.9 Pancreas, unspecified	0.879	0.121
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.878	0.122
E03 Other hypothyroidism	0.876	0.124
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.875	0.125
C20 Malignant neoplasm of rectum	0.875	0.125
F31 Bipolar affective disorder	0.872	0.128
S42.2 Fracture of upper end of humerus	0.872	0.128
H74 Other disorders of middle ear and mastoid	0.868	0.132
T43.3 Phenothiazine antipsychotics and neuroleptics	0.866	0.134
F32.2 Severe depressive episode without psychotic symptoms	0.865	0.135
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.865	0.135
S02 Fracture of skull and facial bones	0.860	0.140
E03.9 Hypothyroidism, unspecified	0.860	0.140
Chapter XX External causes of morbidity and mortality	0.859	0.141
C43-C44 Melanoma and other malignant neoplasms of skin	0.854	0.146
F41.9 Anxiety disorder, unspecified	0.852	0.148
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.850	0.150
B07 Viral warts	0.850	0.150
S60-S69 Injuries to the wrist and hand	0.849	0.151
S06.5 Traumatic subdural haemorrhage	0.849	0.151
S80-S89 Injuries to the knee and lower leg	0.849	0.151
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.846	0.154
G90-G99 Other disorders of the nervous system	0.846	0.154
Chapter XII Diseases of the skin and subcutaneous tissue	0.844	0.156
S70-S79 Injuries to the hip and thigh	0.843	0.157
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.841	0.159
G80-G83 Cerebral palsy and other paralytic syndromes	0.837	0.163
S42.00 Fracture of clavicle (closed)	0.832	0.168
E10.4 With neurological complications	0.824	0.176
F43 Reaction to severe stress, and adjustment disorders	0.823	0.177
S41 Open wound of shoulder and upper arm	0.815	0.185
E27 Other disorders of adrenal gland	0.813	0.187
E14 Unspecified diabetes mellitus	0.812	0.188
C44 Other malignant neoplasms of skin	0.812	0.188
H60-H62 Diseases of external ear	0.811	0.189
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.811	0.189
H90.5 Sensorineural hearing loss, unspecified	0.810	0.190
C53 Malignant neoplasm of cervix uteri	0.808	0.192
S42.20 Fracture of upper end of humerus (closed)	0.807	0.193
H66 Suppurative and unspecified otitis media	0.806	0.194
H90.0 Conductive hearing loss, bilateral	0.805	0.195
T43.2 Other and unspecified antidepressants	0.803	0.197
H72.0 Central perforation of tympanic membrane	0.803	0.197
F60 Specific personality disorders	0.803	0.197
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.803	0.197
S01.1 Open wound of eyelid and periocular area	0.801	0.199
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.800	0.200
S50-S59 Injuries to the elbow and forearm	0.799	0.201
T78 Adverse effects, not elsewhere classified	0.798	0.202
C17 Malignant neoplasm of small intestine	0.796	0.204
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.793	0.207
H71 Cholesteatoma of middle ear	0.792	0.208
C55 Malignant neoplasm of uterus, part unspecified	0.790	0.209
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.790	0.210
T46 Poisoning by agents primarily affecting the cardiovascular system	0.788	0.212
H93 Other disorders of ear, not elsewhere classified	0.787	0.213
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.786	0.214
C25.2 Tail of pancreas	0.784	0.216
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.784	0.216
S42.3 Fracture of shaft of humerus	0.783	0.217
L00-L08 Infections of the skin and subcutaneous tissue	0.783	0.217
C71 Malignant neoplasm of brain	0.782	0.218
F41.1 Generalised anxiety disorder	0.780	0.220
S10-S19 Injuries to the neck	0.779	0.221
S06.6 Traumatic subarachnoid haemorrhage	0.779	0.221
C15 Malignant neoplasm of oesophagus	0.775	0.225
T79-T79 Certain early complications of trauma	0.774	0.226
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.773	0.227
E10.3 With ophthalmic complications	0.772	0.228
C21.1 Anal canal	0.772	0.228
C44.4 Skin of scalp and neck	0.770	0.230
T91 Sequelae of injuries of neck and trunk	0.770	0.230
B35-B49 Mycoses	0.770	0.230
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.769	0.230
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.768	0.232
W00-W19 Falls	0.768	0.232
H91.8 Other specified hearing loss	0.767	0.233
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.767	0.233
T43.5 Other and unspecified antipsychotics and neuroleptics	0.766	0.234
S46 Injury of muscle and tendon at shoulder and upper arm level	0.763	0.236
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.763	0.237
G50-G59 Nerve, nerve root and plexus disorders	0.763	0.237
E50-E64 Other nutritional deficiencies	0.761	0.239
F29 Unspecified nonorganic psychosis	0.759	0.240
S40 Superficial injury of shoulder and upper arm	0.759	0.241
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.759	0.241
S01.8 Open wound of other parts of head	0.758	0.242
G70-G73 Diseases of myoneural junction and muscle	0.758	0.242
G82 Paraplegia and tetraplegia	0.758	0.242
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.757	0.243
T43.0 Tricyclic and tetracyclic antidepressants	0.755	0.245
H74.8 Other specified disorders of middle ear and mastoid	0.755	0.245
C51 Malignant neoplasm of vulva	0.754	0.246
W20-W49 Exposure to inanimate mechanical forces	0.751	0.249
Chapter XXII Codes for special purposes	0.751	0.249
S72 Fracture of femur	0.749	0.250
S02.1 Fracture of base of skull	0.749	0.251
F31.9 Bipolar affective disorder, unspecified	0.749	0.251
S90-S99 Injuries to the ankle and foot	0.749	0.251
T90 Sequelae of injuries of head	0.747	0.253
S30 Superficial injury of abdomen, lower back and pelvis	0.747	0.253
F45 Somatoform disorders	0.744	0.256
E40-E46 Malnutrition	0.743	0.257
E10.1 With ketoacidosis	0.743	0.257
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.742	0.258
C44.7 Skin of lower limb, including hip	0.741	0.259
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.734	0.266
T88 Other complications of surgical and medical care, not elsewhere classified	0.734	0.266
T92 Sequelae of injuries of upper limb	0.734	0.266
S06.2 Diffuse brain injury	0.733	0.267
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.733	0.267
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.732	0.268
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.731	0.269
F25 Schizoaffective disorders	0.731	0.269
H65 Nonsuppurative otitis media	0.731	0.269
G90 Disorders of autonomic nervous system	0.731	0.269
L08 Other local infections of skin and subcutaneous tissue	0.730	0.270
H60 Otitis externa	0.730	0.270
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.729	0.271
E06 Thyroiditis	0.729	0.271
H90.3 Sensorineural hearing loss, bilateral	0.728	0.272
D00-D09 In situ neoplasms	0.726	0.274
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.725	0.275
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.724	0.276
E29 Testicular dysfunction	0.724	0.276
G00-G09 Inflammatory diseases of the central nervous system	0.724	0.276
F99-F99 Unspecified mental disorder	0.721	0.279
S01.2 Open wound of nose	0.720	0.280
E23 Hypofunction and other disorders of pituitary gland	0.720	0.280
S01.0 Open wound of scalp	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E13 Other specified diabetes mellitus	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
D60-D64 Aplastic and other anaemias	0.717	0.283
F38 Other mood [affective] disorders	0.716	0.284
F34 Persistent mood [affective] disorders	0.716	0.284
F30 Manic episode	0.716	0.284
F39 Unspecified mood [affective] disorder	0.716	0.284
F32.8 Other depressive episodes	0.716	0.284
F32.0 Mild depressive episode	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.715	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.715	0.284
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.715	0.284
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.714	0.286
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.713	0.287
F42 Obsessive-compulsive disorder	0.713	0.287
G61 Inflammatory polyneuropathy	0.712	0.288
C26 Malignant neoplasm of other and ill-defined digestive organs	0.711	0.289
C23 Malignant neoplasm of gallbladder	0.711	0.289
F43.1 Posttraumatic stress disorder	0.710	0.290
C44.5 Skin of trunk	0.710	0.290
F60.9 Personality disorder, unspecified	0.710	0.290
S05 Injury of eye and orbit	0.710	0.290
S81 Open wound of lower leg	0.710	0.290
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.709	0.291
H70 Mastoiditis and related conditions	0.709	0.291
H68 Eustachian salpingitis and obstruction	0.709	0.291
H67 Otitis media in diseases classified elsewhere	0.709	0.291
H94 Other disorders of ear in diseases classified elsewhere	0.709	0.291
E12 Malnutrition-related diabetes mellitus	0.709	0.291
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.708	0.291
C64-C68 Malignant neoplasms of urinary tract	0.707	0.292
S48 Traumatic amputation of shoulder and upper arm	0.707	0.293
S45 Injury of blood vessels at shoulder and upper arm level	0.707	0.293
S44 Injury of nerves at shoulder and upper arm level	0.707	0.293
S47 Crushing injury of shoulder and upper arm	0.707	0.293
S66 Injury of muscle and tendon at wrist and hand level	0.707	0.293
E10.8 With unspecified complications	0.706	0.294
E10.7 With multiple complications	0.706	0.294
E10.6 With other specified complications	0.706	0.294
E10.2 With renal complications	0.706	0.294
E10.0 With coma	0.706	0.294
C21.0 Anus, unspecified	0.705	0.295
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.703	0.297
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.703	0.297
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.703	0.297
T41 Poisoning by anaesthetics and therapeutic gases	0.703	0.297
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.703	0.297
T36 Poisoning by systemic antibiotics	0.703	0.297
S08 Traumatic amputation of part of head	0.703	0.297
S07 Crushing injury of head	0.703	0.297
S04 Injury of cranial nerves	0.703	0.297
S03 Dislocation, sprain and strain of joints and ligaments of head	0.703	0.297
G95 Other diseases of spinal cord	0.702	0.298
C57 Malignant neoplasm of other and unspecified female genital organs	0.701	0.298
C58 Malignant neoplasm of placenta	0.701	0.298
C52 Malignant neoplasm of vagina	0.701	0.298
S62 Fracture at wrist and hand level	0.701	0.299
H73 Other disorders of tympanic membrane	0.700	0.300
T68 Hypothermia	0.699	0.300
A80-A89 Viral infections of the central nervous system	0.699	0.301
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.698	0.302
X20-X29 Contact with venomous animals and plants	0.697	0.303
C25.8 Overlapping lesion of pancreas	0.696	0.304
C25.7 Other parts of pancreas	0.696	0.304
C25.4 Endocrine pancreas	0.696	0.304
C25.3 Pancreatic duct	0.696	0.304
C25.1 Body of pancreas	0.696	0.304
S72.3 Fracture of shaft of femur	0.695	0.305
T94 Sequelae of injuries involving multiple and unspecified body regions	0.694	0.306
G63 Polyneuropathy in diseases classified elsewhere	0.693	0.307
W06 Fall involving bed	0.693	0.307
S64 Injury of nerves at wrist and hand level	0.691	0.309
S06.3 Focal brain injury	0.691	0.309
G83 Other paralytic syndromes	0.691	0.309
S42.1 Fracture of scapula	0.691	0.309
S42.9 Fracture of shoulder girdle, part unspecified	0.690	0.310
S42.8 Fracture of other parts of shoulder and upper arm	0.690	0.310
S42.7 Multiple fractures of clavicle, scapula and humerus	0.690	0.310
L60-L75 Disorders of skin appendages	0.690	0.310
E07 Other disorders of thyroid	0.689	0.310
F48 Other neurotic disorders	0.689	0.311
F44 Dissociative [conversion] disorders	0.689	0.311
V10-V19 Pedal cyclist injured in transport accident	0.688	0.312
S02.5 Fracture of tooth	0.687	0.313
C53.9 Cervix uteri, unspecified	0.685	0.315
H72.2 Other marginal perforations of tympanic membrane	0.685	0.315
H72.1 Attic perforation of tympanic membrane	0.685	0.315
C54.9 Corpus uteri, unspecified	0.684	0.316
C54.8 Overlapping lesion of corpus uteri	0.684	0.316
C54.3 Fundus uteri	0.684	0.316
C54.2 Myometrium	0.684	0.316
C54.0 Isthmus uteri	0.684	0.316
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.683	0.317
S02.6 Fracture of mandible	0.683	0.317
H69 Other disorders of Eustachian tube	0.681	0.319
H72.8 Other perforations of tympanic membrane	0.681	0.319
T43.9 Psychotropic drug, unspecified	0.681	0.319
T43.8 Other psychotropic drugs, not elsewhere classified	0.681	0.319
T43.6 Psychostimulants with abuse potential	0.681	0.319
T43.4 Butyrophenone and thioxanthene neuroleptics	0.681	0.319
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.681	0.319
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.681	0.319
S82 Fracture of lower leg, including ankle	0.680	0.320
A30-A49 Other bacterial diseases	0.680	0.320
C71.9 Brain, unspecified	0.680	0.320
H91.3 Deaf mutism, not elsewhere classified	0.678	0.322
H91.2 Sudden idiopathic hearing loss	0.678	0.322
H91.1 Presbycusis	0.678	0.322
H91.0 Ototoxic hearing loss	0.678	0.322
E21.0 Primary hyperparathyroidism	0.677	0.323
E10.5 With peripheral circulatory complications	0.677	0.323
E27.9 Disorder of adrenal gland, unspecified	0.675	0.325
T50.9 Other and unspecified drugs, medicaments and biological substances	0.675	0.325
D37.7 Other digestive organs	0.675	0.325
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.674	0.325
E65-E68 Obesity and other hyperalimentation	0.673	0.327
C22.9 Liver, unspecified	0.672	0.328
T78.3 Angioneurotic oedema	0.672	0.328
T78.2 Anaphylactic shock, unspecified	0.671	0.329
C22.1 Intrahepatic bile duct carcinoma	0.671	0.329
S02.10 Fracture of base of skull (closed)	0.670	0.330
E14.9 Without complications	0.670	0.330
G96 Other disorders of central nervous system	0.670	0.330
H66.9 Otitis media, unspecified	0.669	0.331
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.669	0.331
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.669	0.331
E35 Disorders of endocrine glands in diseases classified elsewhere	0.669	0.331
E34 Other endocrine disorders	0.669	0.331
E32 Diseases of thymus	0.669	0.331
E31 Polyglandular dysfunction	0.669	0.331
E30 Disorders of puberty, not elsewhere classified	0.669	0.331
E26 Hyperaldosteronism	0.669	0.331
E25 Adrenogenital disorders	0.669	0.331
E24 Cushing's syndrome	0.669	0.331
E20 Hypoparathyroidism	0.669	0.331
B00 Herpesviral [herpes simplex] infections	0.668	0.332
S42.4 Fracture of lower end of humerus	0.668	0.332
S06.9 Intracranial injury, unspecified	0.668	0.332
S06.8 Other intracranial injuries	0.668	0.332
S06.7 Intracranial injury with prolonged coma	0.668	0.332
S06.4 Epidural haemorrhage	0.668	0.332
S06.1 Traumatic cerebral oedema	0.668	0.332
F80-F89 Disorders of psychological development	0.667	0.333
B99-B99 Other infectious diseases	0.667	0.333
C22.0 Liver cell carcinoma	0.667	0.333
F23 Acute and transient psychotic disorders	0.666	0.334
T82.1 Mechanical complication of cardiac electronic device	0.666	0.334
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.665	0.335
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.665	0.335
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.665	0.335
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.665	0.335
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.665	0.335
H74.0 Tympanosclerosis	0.665	0.335
T14 Injury of unspecified body region	0.665	0.335
E22 Hyperfunction of pituitary gland	0.665	0.335
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.665	0.335
G56 Mononeuropathies of upper limb	0.664	0.336
D48.6 Breast	0.663	0.337
S20-S29 Injuries to the thorax	0.663	0.337
B90-B94 Sequelae of infectious and parasitic diseases	0.663	0.337
B85-B89 Pediculosis, acariasis and other infestations	0.663	0.337
B65-B83 Helminthiases	0.663	0.337
B50-B64 Protozoal diseases	0.663	0.337
B20-B24 Human immunodeficiency virus [HIV] disease	0.663	0.337
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.663	0.337
A75-A79 Rickettsioses	0.663	0.337
A70-A74 Other diseases caused by chlamydiae	0.663	0.337
A65-A69 Other spirochaetal diseases	0.663	0.337
A20-A28 Certain zoonotic bacterial diseases	0.663	0.337
A15-A19 Tuberculosis	0.663	0.337
T88.7 Unspecified adverse effect of drug or medicament	0.663	0.337
C24.0 Extrahepatic bile duct	0.662	0.338
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.662	0.338
S41.0 Open wound of shoulder	0.662	0.338
S02.0 Fracture of vault of skull	0.661	0.339
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.660	0.340
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.660	0.340
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.660	0.340
F60.3 Emotionally unstable personality disorder	0.659	0.341
D46 Myelodysplastic syndromes	0.659	0.341
T45.0 Antiallergic and antiemetic drugs	0.659	0.341
T11 Other injuries of upper limb, level unspecified	0.658	0.342
S89 Other and unspecified injuries of lower leg	0.658	0.342
G82.2 Paraplegia, unspecified	0.658	0.342
T98 Sequelae of other and unspecified effects of external causes	0.657	0.343
T95 Sequelae of burns, corrosions and frostbite	0.657	0.343
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.657	0.343
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.657	0.343
L50-L54 Urticaria and erythema	0.657	0.343
C15.9 Oesophagus, unspecified	0.656	0.344
C17.0 Duodenum	0.656	0.344
H90.2 Conductive hearing loss, unspecified	0.656	0.344
S72.30 Fracture of shaft of femur (closed)	0.656	0.344
B15-B19 Viral hepatitis	0.655	0.344
H74.3 Other acquired abnormalities of ear ossicles	0.655	0.345
F41.8 Other specified anxiety disorders	0.655	0.345
F41.3 Other mixed anxiety disorders	0.655	0.345
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.655	0.345
S42.30 Fracture of shaft of humerus (closed)	0.655	0.345
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.654	0.346
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.654	0.346
G72 Other myopathies	0.654	0.346
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.653	0.347
T93 Sequelae of injuries of lower limb	0.653	0.347
E28 Ovarian dysfunction	0.652	0.348
C71.1 Frontal lobe	0.651	0.349
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.651	0.349
S06.0 Concussion	0.650	0.350
S00 Superficial injury of head	0.650	0.350
G62 Other polyneuropathies	0.649	0.351
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.649	0.351
Chapter XIV Diseases of the genitourinary system	0.648	0.352
S71 Open wound of hip and thigh	0.647	0.353
F20 Schizophrenia	0.647	0.353
D45 Polycythaemia vera	0.646	0.354
S01.7 Multiple open wounds of head	0.646	0.354
F41.2 Mixed anxiety and depressive disorder	0.645	0.355
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.644	0.356
E00 Congenital iodine-deficiency syndrome	0.644	0.356
E02 Subclinical iodine-deficiency hypothyroidism	0.644	0.356
B95-B98 Bacterial, viral and other infectious agents	0.642	0.358
T75 Effects of other external causes	0.642	0.358
T74 Maltreatment syndromes	0.642	0.358
T73 Effects of other deprivation	0.642	0.358
T70 Effects of air pressure and water pressure	0.642	0.358
T69 Other effects of reduced temperature	0.642	0.358
T67 Effects of heat and light	0.642	0.358
T71 Asphyxiation	0.642	0.358
T66 Unspecified effects of radiation	0.642	0.358
T13 Other injuries of lower limb, level unspecified	0.642	0.358
S49 Other and unspecified injuries of shoulder and upper arm	0.641	0.358
C69 Malignant neoplasm of eye and adnexa	0.640	0.360
E27.8 Other specified disorders of adrenal gland	0.640	0.360
W06.0 Home	0.640	0.360
D63 Anaemia in chronic diseases classified elsewhere	0.639	0.361
S86 Injury of muscle and tendon at lower leg level	0.639	0.361
E27.1 Primary adrenocortical insufficiency	0.638	0.362
F28 Other nonorganic psychotic disorders	0.638	0.362
F24 Induced delusional disorder	0.638	0.362
F21 Schizotypal disorder	0.638	0.362
V40-V49 Car occupant injured in transport accident	0.637	0.363
H60.9 Otitis externa, unspecified	0.637	0.363
B37 Candidiasis	0.637	0.363
T80 Complications following infusion, transfusion and therapeutic injection	0.636	0.364
S52 Fracture of forearm	0.636	0.364
S42.01 Fracture of clavicle (open)	0.635	0.364
S50 Superficial injury of forearm	0.635	0.365
F68 Other disorders of adult personality and behaviour	0.635	0.365
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.635	0.365
F65 Disorders of sexual preference	0.635	0.365
F64 Gender identity disorders	0.635	0.365
F63 Habit and impulse disorders	0.635	0.365
F62 Enduring personality changes, not attributable to brain damage and disease	0.635	0.365
F69 Unspecified disorder of adult personality and behaviour	0.635	0.365
F61 Mixed and other personality disorders	0.635	0.365
G91 Hydrocephalus	0.634	0.365
T15-T19 Effects of foreign body entering through natural orifice	0.633	0.367
C21.8 Overlapping lesion of rectum, anus and anal canal	0.633	0.367
C21.2 Cloacogenic zone	0.633	0.367
F43.2 Adjustment disorders	0.631	0.369
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.629	0.370
B06 Rubella [German measles]	0.629	0.370
B05 Measles	0.629	0.370
B01 Varicella [chickenpox]	0.629	0.370
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.629	0.370
B04 Monkeypox	0.629	0.370
B03 Smallpox	0.629	0.370
G51 Facial nerve disorders	0.629	0.371
G90.9 Disorder of autonomic nervous system, unspecified	0.629	0.371
N17-N19 Renal failure	0.628	0.372
S41.1 Open wound of upper arm	0.628	0.372
E03.8 Other specified hypothyroidism	0.628	0.372
E03.5 Myxoedema coma	0.628	0.372
E03.4 Atrophy of thyroid (acquired)	0.628	0.372
E03.3 Postinfectious hypothyroidism	0.628	0.372
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.628	0.372
E03.1 Congenital hypothyroidism without goitre	0.628	0.372
E03.0 Congenital hypothyroidism with diffuse goitre	0.628	0.372
S02.3 Fracture of orbital floor	0.628	0.372
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.627	0.372
C70 Malignant neoplasm of meninges	0.627	0.372
G35-G37 Demyelinating diseases of the central nervous system	0.627	0.373
T90.9 Sequelae of unspecified injury of head	0.626	0.374
F32.1 Moderate depressive episode	0.626	0.374
T82.4 Mechanical complication of vascular dialysis catheter	0.626	0.374
F31.8 Other bipolar affective disorders	0.625	0.375
F31.7 Bipolar affective disorder, currently in remission	0.625	0.375
F31.6 Bipolar affective disorder, current episode mixed	0.625	0.375
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.625	0.375
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.625	0.375
S42.21 Fracture of upper end of humerus (open)	0.625	0.375
D41.4 Bladder	0.625	0.375
A50-A64 Infections with a predominantly sexual mode of transmission	0.624	0.376
H74.9 Disorder of middle ear and mastoid, unspecified	0.623	0.377
H74.2 Discontinuity and dislocation of ear ossicles	0.623	0.377
H74.1 Adhesive middle ear disease	0.623	0.377
H93.9 Disorder of ear, unspecified	0.622	0.378
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.621	0.379
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.620	0.380
S37 Injury of urinary and pelvic organs	0.620	0.380
S36 Injury of intra-abdominal organs	0.620	0.380
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.620	0.380
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.620	0.380
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.620	0.380
S31 Open wound of abdomen, lower back and pelvis	0.620	0.380
T91.1 Sequelae of fracture of spine	0.619	0.381
W13 Fall from, out of or through building or structure	0.619	0.381
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.619	0.381
F25.9 Schizoaffective disorder, unspecified	0.617	0.383
S02.9 Fracture of skull and facial bones, part unspecified	0.616	0.384
S02.8 Fractures of other skull and facial bones	0.616	0.384
S02.7 Multiple fractures involving skull and facial bones	0.616	0.384
X60-X84 Intentional self-harm	0.616	0.384
N10-N16 Renal tubulo-interstitial diseases	0.616	0.384
N18 Chronic renal failure	0.616	0.384
Y35-Y36 Legal intervention and operations of war	0.616	0.384
Y10-Y34 Event of undetermined intent	0.616	0.384
Y00-Y09 Assault	0.616	0.384
X85-X99 Assault	0.616	0.384

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations