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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77923642
log Bayes Factor = 16.5171
Chromosome 6   position 167,359,606  (GRCh37) Explore rs77923642 on Ensembl!
Variant rs77923642 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
M13 Other arthritis
0.993 0.007 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.991 0.009 0.000
M13.9 Arthritis, unspecified
0.991 0.009 0.000
M54 Dorsalgia
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
Z86.4 Personal history of psychoactive substance abuse
0.985 0.015 0.000
Z86 Personal history of certain other diseases
0.985 0.015 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.984 0.016 0.000
S80-S89 Injuries to the knee and lower leg
0.981 0.019 0.000
J40-J47 Chronic lower respiratory diseases
0.976 0.024 0.000
Chapter IX Diseases of the circulatory system
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.971 0.029 0.000
Chapter XIV Diseases of the genitourinary system
0.962 0.038 0.000
M54.3 Sciatica
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.957 0.043 0.000
I42 Cardiomyopathy
0.956 0.044 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.946 0.054 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.943 0.057 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.940 0.060 0.000
S82 Fracture of lower leg, including ankle
0.939 0.061 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.937 0.063 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.936 0.064 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.935 0.065 0.000
Chapter VIII Diseases of the ear and mastoid process
0.935 0.065 0.000
J95-J99 Other diseases of the respiratory system
0.930 0.070 0.000
Z87 Personal history of other diseases and conditions
0.926 0.074 0.000
N95 Menopausal and other perimenopausal disorders
0.925 0.075 0.000
Y86 Sequelae of other accidents
0.921 0.079 0.000
I60-I69 Cerebrovascular diseases
0.920 0.080 0.000
Z96 Presence of other functional implants
0.915 0.085 0.000
M54.36 Sciatica (Lumbar region)
0.913 0.087 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.910 0.090 0.000
R00 Abnormalities of heart beat
0.910 0.090 0.000
I10-I15 Hypertensive diseases
0.906 0.094 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.906 0.094 0.000
N95.0 Postmenopausal bleeding
0.905 0.095 0.000
J43 Emphysema
0.904 0.096 0.000
N94.1 Dyspareunia
0.904 0.096 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.898 0.102 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.894 0.106 0.000
M70-M79 Other soft tissue disorders
0.893 0.107 0.000
H60-H62 Diseases of external ear
0.892 0.108 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.890 0.110 0.000
M20-M25 Other joint disorders
0.889 0.111 0.000
N81 Female genital prolapse
0.887 0.113 0.000
J98 Other respiratory disorders
0.886 0.114 0.000
Chapter XXII Codes for special purposes
0.884 0.116 0.000
I47 Paroxysmal tachycardia
0.884 0.116 0.000
R00.1 Bradycardia, unspecified
0.883 0.117 0.000
S60-S69 Injuries to the wrist and hand
0.883 0.117 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.882 0.118 0.000
I46 Cardiac arrest
0.881 0.118 0.000
G40-G47 Episodic and paroxysmal disorders
0.880 0.120 0.000
I44 Atrioventricular and left bundle-branch block
0.880 0.120 0.000
Chapter I Certain infectious and parasitic diseases
0.879 0.121 0.000
Chapter II Neoplasms
0.879 0.121 0.000
I42.9 Cardiomyopathy, unspecified
0.877 0.123 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.877 0.123 0.000
E10-E14 Diabetes mellitus
0.876 0.124 0.000
S70-S79 Injuries to the hip and thigh
0.876 0.124 0.000
E00-E07 Disorders of thyroid gland
0.870 0.130 0.000
N94.6 Dysmenorrhoea, unspecified
0.870 0.130 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.867 0.133 0.000
I42.2 Other hypertrophic cardiomyopathy
0.866 0.134 0.000
H61 Other disorders of external ear
0.864 0.136 0.000
S80 Superficial injury of lower leg
0.864 0.136 0.000
S40-S49 Injuries to the shoulder and upper arm
0.863 0.137 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.863 0.137 0.000
I50 Heart failure
0.859 0.141 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.859 0.141 0.000
J60-J70 Lung diseases due to external agents
0.856 0.144 0.000
N25-N29 Other disorders of kidney and ureter
0.856 0.144 0.000
J43.9 Emphysema, unspecified
0.853 0.147 0.000
R00.2 Palpitations
0.853 0.147 0.000
E65-E68 Obesity and other hyperalimentation
0.848 0.152 0.000
M54.5 Low back pain
0.847 0.153 0.000
M51 Other intervertebral disk disorders
0.847 0.153 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.846 0.154 0.000
J98.1 Pulmonary collapse
0.845 0.155 0.000
S82.3 Fracture of lower end of tibia
0.844 0.156 0.000
Z87.0 Personal history of diseases of the respiratory system
0.844 0.156 0.000
Z96.8 Presence of other specified functional implants
0.844 0.156 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.843 0.157 0.000
Z93 Artificial opening status
0.841 0.159 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.840 0.160 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.840 0.160 0.000
J45 Asthma
0.836 0.164 0.000
I46.0 Cardiac arrest with successful resuscitation
0.835 0.165 0.000
M80-M85 Disorders of bone density and structure
0.834 0.166 0.000
G20-G26 Extrapyramidal and movement disorders
0.832 0.168 0.000
S90-S99 Injuries to the ankle and foot
0.832 0.168 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.831 0.169 0.000
J84 Other interstitial pulmonary diseases
0.829 0.171 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.828 0.172 0.000
M54.39 Sciatica (Site unspecified)
0.825 0.175 0.000
R06 Abnormalities of breathing
0.824 0.176 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.824 0.176 0.000
J44 Other chronic obstructive pulmonary disease
0.824 0.176 0.000
I44.7 Left bundle-branch block, unspecified
0.824 0.176 0.000
J81 Pulmonary oedema
0.824 0.176 0.000
J30-J39 Other diseases of upper respiratory tract
0.823 0.177 0.000
M54.56 Low back pain (Lumbar region)
0.822 0.178 0.000
I61 Intracerebral haemorrhage
0.821 0.178 0.000
M54.1 Radiculopathy
0.821 0.179 0.000
Z72 Problems related to lifestyle
0.820 0.180 0.000
M86-M90 Other osteopathies
0.819 0.181 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
M54.2 Cervicalgia
0.817 0.183 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.816 0.184 0.000
E11 Non-insulin-dependent diabetes mellitus
0.816 0.184 0.000
R05 Cough
0.815 0.185 0.000
I10 Essential (primary) hypertension
0.815 0.185 0.000
N95.2 Postmenopausal atrophic vaginitis
0.814 0.186 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.813 0.187 0.000
B25-B34 Other viral diseases
0.812 0.188 0.000
S61 Open wound of wrist and hand
0.812 0.188 0.000
X60-X84 Intentional self-harm
0.811 0.189 0.000
M07 Psoriatic and enteropathic arthropathies
0.810 0.190 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.807 0.193 0.000
S50-S59 Injuries to the elbow and forearm
0.806 0.194 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.806 0.194 0.000
M23 Internal derangement of knee
0.804 0.196 0.000
R00.0 Tachycardia, unspecified
0.803 0.197 0.000
G90-G99 Other disorders of the nervous system
0.802 0.198 0.000
S82.6 Fracture of lateral malleolus
0.799 0.201 0.000
M50 Cervical disk disorders
0.799 0.201 0.000
S82.8 Fractures of other parts of lower leg
0.799 0.201 0.000
Z96.0 Presence of urogenital implants
0.798 0.202 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
R26 Abnormalities of gait and mobility
0.795 0.205 0.000
M79.8 Other specified soft tissue disorders
0.795 0.205 0.000
I69 Sequelae of cerebrovascular disease
0.793 0.207 0.000
M10 Gout
0.791 0.209 0.000
N81.1 Cystocele
0.791 0.209 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.789 0.211 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.787 0.213 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
J00-J06 Acute upper respiratory infections
0.786 0.214 0.000
J20-J22 Other acute lower respiratory infections
0.785 0.215 0.000
N81.4 Uterovaginal prolapse, unspecified
0.782 0.218 0.000
M91-M94 Chondropathies
0.780 0.220 0.000
I42.0 Dilated cardiomyopathy
0.779 0.221 0.000
H90-H95 Other disorders of ear
0.778 0.222 0.000
S82.30 Fracture of lower end of tibia (closed)
0.777 0.223 0.000
S81 Open wound of lower leg
0.776 0.224 0.000
Y85 Sequelae of transport accidents
0.775 0.225 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.774 0.226 0.000
L50-L54 Urticaria and erythema
0.770 0.230 0.000
E16 Other disorders of pancreatic internal secretion
0.768 0.232 0.000
I47.2 Ventricular tachycardia
0.767 0.232 0.000
C15-C26 Malignant neoplasms of digestive organs
0.766 0.234 0.000
N10-N16 Renal tubulo-interstitial diseases
0.764 0.236 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.763 0.237 0.000
B34 Viral infection of unspecified site
0.763 0.237 0.000
I67 Other cerebrovascular diseases
0.762 0.238 0.000
I31 Other diseases of pericardium
0.761 0.239 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.761 0.239 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.760 0.240 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.760 0.240 0.000
M53 Other dorsopathies, not elsewhere classified
0.758 0.242 0.000
M54.9 Dorsalgia, unspecified
0.756 0.244 0.000
N30-N39 Other diseases of urinary system
0.756 0.244 0.000
M40-M43 Deforming dorsopathies
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.754 0.246 0.000
H61.0 Perichondritis of external ear
0.753 0.247 0.000
M11 Other crystal arthropathies
0.752 0.248 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.751 0.249 0.000
N94.4 Primary dysmenorrhoea
0.751 0.249 0.000
J47 Bronchiectasis
0.750 0.250 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.750 0.250 0.000
I47.1 Supraventricular tachycardia
0.750 0.250 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.749 0.251 0.000
J46 Status asthmaticus
0.749 0.251 0.000
I36 Nonrheumatic tricuspid valve disorders
0.748 0.252 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.748 0.252 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.748 0.252 0.000
N00-N08 Glomerular diseases
0.747 0.253 0.000
Z96.6 Presence of orthopaedic joint implants
0.747 0.253 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.746 0.254 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
X20-X29 Contact with venomous animals and plants
0.745 0.255 0.000
M15-M19 Arthrosis
0.744 0.256 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.744 0.256 0.000
D00-D09 In situ neoplasms
0.742 0.258 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.742 0.258 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.742 0.258 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.741 0.259 0.000
R01 Cardiac murmurs and other cardiac sounds
0.741 0.259 0.000
Z83 Family history of other specific disorders
0.740 0.260 0.000
J36 Peritonsillar abscess
0.740 0.260 0.000
E11.4 With neurological complications
0.738 0.262 0.000
S80.0 Contusion of knee
0.737 0.263 0.000
E40-E46 Malnutrition
0.737 0.263 0.000
M45-M49 Spondylopathies
0.737 0.263 0.000
Z75 Problems related to medical facilities and other health care
0.736 0.264 0.000
N99-N99 Other disorders of the genitourinary system
0.734 0.265 0.000
J42 Unspecified chronic bronchitis
0.734 0.266 0.000
I50.9 Heart failure, unspecified
0.734 0.266 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.734 0.266 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.734 0.266 0.000
G30-G32 Other degenerative diseases of the nervous system
0.734 0.266 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.733 0.267 0.000
Z93.2 Ileostomy status
0.733 0.267 0.000
N87 Dysplasia of cervix uteri
0.733 0.267 0.000
H61.2 Impacted cerumen
0.732 0.268 0.000
E66 Obesity
0.731 0.269 0.000
S00-S09 Injuries to the head
0.731 0.269 0.000
R25 Abnormal involuntary movements
0.730 0.270 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.728 0.272 0.000
B34.9 Viral infection, unspecified
0.728 0.272 0.000
Chapter V Mental and behavioural disorders
0.728 0.272 0.000
H61.1 Non-infective disorders of pinna
0.728 0.272 0.000
N81.5 Vaginal enterocele
0.726 0.274 0.000
J45.0 Predominantly allergic asthma
0.726 0.274 0.000
Z36 Antenatal screening
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.725 0.274 0.000
C51-C58 Malignant neoplasms of female genital organs
0.724 0.276 0.000
E04 Other non-toxic goitre
0.723 0.277 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.722 0.278 0.000
I12 Hypertensive renal disease
0.722 0.278 0.000
Z72.1 Alcohol use
0.721 0.279 0.000
Z74 Problems related to care-provider dependency
0.720 0.280 0.000
Z34 Supervision of normal pregnancy
0.718 0.281 0.000
Z97 Presence of other devices
0.718 0.282 0.000
M54.37 Sciatica (Lumbosacral region)
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
W00-W19 Falls
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S60 Superficial injury of wrist and hand
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
N39 Other disorders of urinary system
0.714 0.286 0.000
O16 Unspecified maternal hypertension
0.713 0.287 0.000
S72 Fracture of femur
0.713 0.287 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.713 0.287 0.000
H61.3 Acquired stenosis of external ear canal
0.712 0.287 0.000
Z96.7 Presence of other bone and tendon implants
0.712 0.287 0.000
M13.8 Other specified arthritis
0.712 0.288 0.000
M13.1 Monoarthritis, not elsewhere classified
0.712 0.288 0.000
S61.8 Open wound of other parts of wrist and hand
0.712 0.288 0.000
R09.3 Abnormal sputum
0.712 0.288 0.000
S82.1 Fracture of upper end of tibia
0.711 0.289 0.000
M22 Disorders of patella
0.711 0.289 0.000
S79 Other and unspecified injuries of hip and thigh
0.711 0.289 0.000
M13.93 Arthritis, unspecified (Forearm)
0.711 0.289 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.711 0.289 0.000
I11 Hypertensive heart disease
0.711 0.289 0.000
M54.8 Other dorsalgia
0.709 0.290 0.000
M54.6 Pain in thoracic spine
0.709 0.290 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.290 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.707 0.292 0.000
M13.98 Arthritis, unspecified (Other)
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.706 0.294 0.000
Z84 Family history of other conditions
0.706 0.294 0.000
Z81 Family history of mental and behavioural disorders
0.706 0.294 0.000
M05 Seropositive rheumatoid arthritis
0.705 0.295 0.000
Z87.8 Personal history of other specified conditions
0.705 0.295 0.000
N26 Unspecified contracted kidney
0.705 0.295 0.000
R06.0 Dyspnoea
0.704 0.296 0.000
I44.0 Atrioventricular block, first degree
0.704 0.296 0.000
S82.2 Fracture of shaft of tibia
0.704 0.296 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.704 0.296 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.703 0.297 0.000
S88 Traumatic amputation of lower leg
0.703 0.297 0.000
S87 Crushing injury of lower leg
0.703 0.297 0.000
S86 Injury of muscle and tendon at lower leg level
0.703 0.297 0.000
S85 Injury of blood vessels at lower leg level
0.703 0.297 0.000
S84 Injury of nerves at lower leg level
0.703 0.297 0.000
J98.4 Other disorders of lung
0.703 0.297 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
E16.2 Hypoglycaemia, unspecified
0.702 0.298 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.702 0.298 0.000
N81.3 Complete uterovaginal prolapse
0.702 0.298 0.000
D69 Purpura and other haemorrhagic conditions
0.702 0.298 0.000
M72 Fibroblastic disorders
0.701 0.299 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.300 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.700 0.300 0.000
M79.1 Myalgia
0.699 0.300 0.000
I00-I02 Acute rheumatic fever
0.699 0.301 0.000
S82.60 Fracture of lateral malleolus (closed)
0.699 0.301 0.000
M34 Systemic sclerosis
0.698 0.301 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.698 0.302 0.000
M23.3 Other meniscus derangements
0.698 0.302 0.000
G45.3 Amaurosis fugax
0.698 0.302 0.000
N39.3 Stress incontinence
0.698 0.302 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.698 0.302 0.000
S80.8 Other superficial injuries of lower leg
0.698 0.302 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.697 0.302 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.697 0.303 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.697 0.303 0.000
E50-E64 Other nutritional deficiencies
0.697 0.303 0.000
S68 Traumatic amputation of wrist and hand
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.696 0.304 0.000
I48 Atrial fibrillation and flutter
0.696 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.696 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.696 0.304 0.000
I40 Acute myocarditis
0.696 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.696 0.304 0.000
I37 Pulmonary valve disorders
0.696 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.696 0.304 0.000
I30 Acute pericarditis
0.696 0.304 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.695 0.305 0.000
N81.2 Incomplete uterovaginal prolapse
0.695 0.305 0.000
G25 Other extrapyramidal and movement disorders
0.694 0.305 0.000
M54.22 Cervicalgia (Cervical region)
0.694 0.306 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.694 0.306 0.000
G44 Other headache syndromes
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.692 0.308 0.000
Q50-Q56 Congenital malformations of genital organs
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
S99 Other and unspecified injuries of ankle and foot
0.691 0.309 0.000
M21 Other acquired deformities of limbs
0.690 0.310 0.000
M51.2 Other specified intervertebral disk displacement
0.689 0.310 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.689 0.311 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.689 0.311 0.000
I50.1 Left ventricular failure
0.689 0.311 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.688 0.311 0.000
M54.35 Sciatica (Thoracolumbar region)
0.688 0.311 0.000
M54.34 Sciatica-Thoracic
0.688 0.311 0.000
M54.33 Sciatica-Cervicothoracic
0.688 0.311 0.000
M54.32 Sciatica-Cervical
0.688 0.311 0.000
M54.31 Sciatica-Occipit-atl-axl
0.688 0.311 0.000
M54.30 Sciatica (Multiple sites in spine)
0.688 0.311 0.000
Z29 Need for other prophylactic measures
0.687 0.313 0.000
M89 Other disorders of bone
0.686 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.686 0.314 0.000
C20 Malignant neoplasm of rectum
0.686 0.314 0.000
I42.8 Other cardiomyopathies
0.685 0.314 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.685 0.314 0.000
I42.6 Alcoholic cardiomyopathy
0.685 0.314 0.000
I42.5 Other restrictive cardiomyopathy
0.685 0.314 0.000
I42.4 Endocardial fibroelastosis
0.685 0.314 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.685 0.314 0.000
M13.0 Polyarthritis, unspecified
0.685 0.315 0.000
L40-L45 Papulosquamous disorders
0.684 0.316 0.000
S40 Superficial injury of shoulder and upper arm
0.684 0.316 0.000
E06 Thyroiditis
0.684 0.316 0.000
S61.0 Open wound of finger(s) without damage to nail
0.683 0.317 0.000
E03 Other hypothyroidism
0.681 0.319 0.000
Z89 Acquired absence of limb
0.681 0.319 0.000
O20 Haemorrhage in early pregnancy
0.681 0.319 0.000
Z72.0 Tobacco use
0.681 0.319 0.000
N28.1 Cyst of kidney, acquired
0.680 0.320 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.679 0.321 0.000
M54.16 Radiculopathy (Lumbar region)
0.679 0.321 0.000
N98 Complications associated with artificial fertilisation
0.678 0.322 0.000
N91 Absent, scanty and rare menstruation
0.678 0.322 0.000
N82 Fistulae involving female genital tract
0.678 0.322 0.000
N96 Habitual aborter
0.678 0.322 0.000
T79-T79 Certain early complications of trauma
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.323 0.000
M07.3 Other psoriatic arthropathies
0.676 0.324 0.000
M17 Gonarthrosis [arthrosis of knee]
0.676 0.324 0.000
N94.5 Secondary dysmenorrhoea
0.676 0.324 0.000
N94.2 Vaginismus
0.676 0.324 0.000
N94.0 Mittelschmerz
0.676 0.324 0.000
J34 Other disorders of nose and nasal sinuses
0.675 0.325 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.674 0.326 0.000
I62 Other nontraumatic intracranial haemorrhage
0.674 0.326 0.000
S70 Superficial injury of hip and thigh
0.674 0.326 0.000
Q60-Q64 Congenital malformations of the urinary system
0.674 0.326 0.000
V80-V89 Other land transport accidents
0.674 0.326 0.000
B95-B98 Bacterial, viral and other infectious agents
0.674 0.326 0.000
S82.9 Fracture of lower leg, part unspecified
0.673 0.327 0.000
S82.7 Multiple fractures of lower leg
0.673 0.327 0.000
M54.4 Lumbago with sciatica
0.673 0.327 0.000
M80 Osteoporosis with pathological fracture
0.673 0.327 0.000
S89 Other and unspecified injuries of lower leg
0.672 0.328 0.000
R27 Other lack of coordination
0.672 0.328 0.000
U88 Agent resistant to multiple antibiotics
0.671 0.329 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.671 0.329 0.000
J80 Adult respiratory distress syndrome
0.671 0.329 0.000
E11.9 Without complications
0.671 0.329 0.000
Y89 Sequelae of other external causes
0.671 0.329 0.000
Y88 Sequelae of surgical and medical care as external cause
0.671 0.329 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.671 0.329 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.671 0.329 0.000
T17 Foreign body in respiratory tract
0.671 0.329 0.000
I44.2 Atrioventricular block, complete
0.670 0.330 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.670 0.330 0.000
M79.7 Fibromyalgia
0.670 0.330 0.000
S61.7 Multiple open wounds of wrist and hand
0.669 0.331 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.669 0.331 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.668 0.332 0.000
E14 Unspecified diabetes mellitus
0.668 0.332 0.000
C54 Malignant neoplasm of corpus uteri
0.668 0.332 0.000
M23.8 Other internal derangements of knee
0.668 0.332 0.000
C18 Malignant neoplasm of colon
0.668 0.332 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.667 0.333 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.667 0.333 0.000
J96 Respiratory failure, not elsewhere classified
0.667 0.333 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.667 0.333 0.000
N89 Other noninflammatory disorders of vagina
0.667 0.333 0.000
N94.3 Premenstrual tension syndrome
0.666 0.334 0.000
B35-B49 Mycoses
0.666 0.334 0.000
M79.0 Rheumatism, unspecified
0.665 0.335 0.000
M71 Other bursopathies
0.665 0.335 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.664 0.336 0.000
M65-M68 Disorders of synovium and tendon
0.664 0.336 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.663 0.337 0.000
N95.3 States associated with artificial menopause
0.663 0.337 0.000
Q80-Q89 Other congenital malformations
0.663 0.337 0.000
D50-D53 Nutritional anaemias
0.662 0.338 0.000
S41 Open wound of shoulder and upper arm
0.662 0.338 0.000
S51 Open wound of forearm
0.662 0.338 0.000
Z91.6 Personal history of other physical trauma
0.662 0.338 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.661 0.339 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.661 0.339 0.000
S90 Superficial injury of ankle and foot
0.660 0.339 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.660 0.340 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.659 0.341 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.659 0.341 0.000
O26.9 Pregnancy-related condition, unspecified
0.659 0.341 0.000
M25 Other joint disorders, not elsewhere classified
0.658 0.342 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.658 0.342 0.000
G81 Hemiplegia
0.658 0.342 0.000
Z96.9 Presence of functional implant, unspecified
0.656 0.344 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.656 0.344 0.000
Z96.4 Presence of endocrine implants
0.656 0.344 0.000
Z96.3 Presence of artificial larynx
0.656 0.344 0.000
Z96.2 Presence of otological and audiological implants
0.656 0.344 0.000
Z36.9 Antenatal screening, unspecified
0.656 0.344 0.000
S50 Superficial injury of forearm
0.656 0.344 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.655 0.344 0.000
Q00-Q07 Congenital malformations of the nervous system
0.655 0.344 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.655 0.345 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.655 0.345 0.000
J69 Pneumonitis due to solids and liquids
0.654 0.345 0.000
L60-L75 Disorders of skin appendages
0.654 0.346 0.000
I63 Cerebral infarction
0.654 0.346 0.000
S56 Injury of muscle and tendon at forearm level
0.654 0.346 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.654 0.346 0.000
O26.8 Other specified pregnancy-related conditions
0.654 0.346 0.000
Z39 Postpartum care and examination
0.653 0.346 0.000
N03 Chronic nephritic syndrome
0.652 0.348 0.000
N60-N64 Disorders of breast
0.652 0.348 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.651 0.349 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.650 0.349 0.000
D45 Polycythaemia vera
0.650 0.350 0.000
M35 Other systemic involvement of connective tissue
0.650 0.350 0.000
G40 Epilepsy
0.650 0.350 0.000
Z91.5 Personal history of self-harm
0.650 0.350 0.000
I15 Secondary hypertension
0.649 0.350 0.000
I13 Hypertensive heart and renal disease
0.649 0.350 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.650 0.350 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.649 0.351 0.000
D69.6 Thrombocytopenia, unspecified
0.649 0.351 0.000
E11.5 With peripheral circulatory complications
0.649 0.351 0.000
H93 Other disorders of ear, not elsewhere classified
0.649 0.351 0.000
R06.2 Wheezing
0.648 0.352 0.000
G24 Dystonia
0.648 0.352 0.000
J43.8 Other emphysema
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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