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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80026531
log Bayes Factor = 23.2313
Chromosome 6   position 30,744,768  (GRCh37) Explore rs80026531 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z88.0 Personal history of allergy to penicillin
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.998 0.002 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.994 0.006 0.000
E20-E35 Disorders of other endocrine glands
0.988 0.012 0.000
S60-S69 Injuries to the wrist and hand
0.987 0.013 0.000
F41 Other anxiety disorders
0.987 0.013 0.000
N20-N23 Urolithiasis
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.986 0.014 0.000
F41.2 Mixed anxiety and depressive disorder
0.986 0.014 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.985 0.015 0.000
F30-F39 Mood [affective] disorders
0.984 0.016 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
M25 Other joint disorders, not elsewhere classified
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.977 0.023 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.977 0.023 0.000
M70-M79 Other soft tissue disorders
0.975 0.025 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.971 0.029 0.000
C44 Other malignant neoplasms of skin
0.971 0.029 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.968 0.032 0.000
C44.3 Skin of other and unspecified parts of face
0.968 0.032 0.000
M13 Other arthritis
0.968 0.032 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.962 0.038 0.000
N10-N16 Renal tubulo-interstitial diseases
0.959 0.041 0.000
N20 Calculus of kidney and ureter
0.958 0.042 0.000
N94.6 Dysmenorrhoea, unspecified
0.958 0.042 0.000
M13.9 Arthritis, unspecified
0.957 0.043 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.956 0.044 0.000
M24 Other specific joint derangements
0.955 0.045 0.000
F33 Recurrent depressive disorder
0.952 0.048 0.000
S61 Open wound of wrist and hand
0.952 0.048 0.000
E70-E90 Metabolic disorders
0.948 0.052 0.000
M75 Shoulder lesions
0.946 0.054 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.945 0.055 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.944 0.056 0.000
N17-N19 Renal failure
0.941 0.059 0.000
E00-E07 Disorders of thyroid gland
0.936 0.064 0.000
S61.0 Open wound of finger(s) without damage to nail
0.932 0.068 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.929 0.071 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.928 0.072 0.000
S00-S09 Injuries to the head
0.927 0.073 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.924 0.076 0.000
F33.9 Recurrent depressive disorder, unspecified
0.921 0.079 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.920 0.080 0.000
C44.4 Skin of scalp and neck
0.919 0.081 0.000
I71 Aortic aneurysm and dissection
0.916 0.084 0.000
I25.1 Atherosclerotic heart disease
0.912 0.088 0.000
E86 Volume depletion
0.907 0.093 0.000
N19 Unspecified renal failure
0.904 0.096 0.000
M75.1 Rotator cuff syndrome
0.903 0.097 0.000
N20.1 Calculus of ureter
0.903 0.097 0.000
F31 Bipolar affective disorder
0.903 0.097 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.901 0.099 0.000
E29 Testicular dysfunction
0.895 0.105 0.000
D00-D09 In situ neoplasms
0.895 0.105 0.000
E03 Other hypothyroidism
0.891 0.109 0.000
N89 Other noninflammatory disorders of vagina
0.886 0.114 0.000
M25.4 Effusion of joint
0.885 0.115 0.000
D45 Polycythaemia vera
0.884 0.116 0.000
M80-M85 Disorders of bone density and structure
0.881 0.119 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.881 0.119 0.000
N97 Female infertility
0.879 0.121 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.879 0.121 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.878 0.122 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.877 0.123 0.000
M13.94 Arthritis, unspecified (Hand)
0.873 0.127 0.000
D48.1 Connective and other soft tissue
0.873 0.127 0.000
S70-S79 Injuries to the hip and thigh
0.871 0.129 0.000
N23 Unspecified renal colic
0.871 0.129 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.869 0.131 0.000
E23 Hypofunction and other disorders of pituitary gland
0.869 0.131 0.000
M25.8 Other specified joint disorders
0.868 0.132 0.000
F43 Reaction to severe stress, and adjustment disorders
0.865 0.135 0.000
S06 Intracranial injury
0.862 0.138 0.000
S64 Injury of nerves at wrist and hand level
0.859 0.141 0.000
M65-M68 Disorders of synovium and tendon
0.859 0.141 0.000
N92 Excessive, frequent and irregular menstruation
0.859 0.141 0.000
N10 Acute tubulo-interstitial nephritis
0.854 0.146 0.000
I24 Other acute ischaemic heart diseases
0.854 0.146 0.000
M45-M49 Spondylopathies
0.851 0.149 0.000
E65-E68 Obesity and other hyperalimentation
0.848 0.152 0.000
M24.2 Disorder of ligament
0.847 0.153 0.000
Y52 Agents primarily affecting the cardiovascular system
0.846 0.154 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.845 0.155 0.000
Chapter VII Diseases of the eye and adnexa
0.844 0.156 0.000
E03.9 Hypothyroidism, unspecified
0.844 0.156 0.000
M75.4 Impingement syndrome of shoulder
0.842 0.158 0.000
N60-N64 Disorders of breast
0.841 0.159 0.000
I30-I52 Other forms of heart disease
0.840 0.160 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.840 0.160 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.838 0.162 0.000
H53-H54 Visual disturbances and blindness
0.834 0.166 0.000
M21 Other acquired deformities of limbs
0.834 0.166 0.000
F40 Phobic anxiety disorders
0.833 0.167 0.000
H53 Visual disturbances
0.832 0.168 0.000
Chapter XXII Codes for special purposes
0.832 0.168 0.000
I20 Angina pectoris
0.831 0.169 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.830 0.170 0.000
S01 Open wound of head
0.830 0.170 0.000
E29.1 Testicular hypofunction
0.829 0.171 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.829 0.171 0.000
D41.4 Bladder
0.829 0.171 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.827 0.173 0.000
I05-I09 Chronic rheumatic heart diseases
0.823 0.177 0.000
E50-E64 Other nutritional deficiencies
0.821 0.178 0.000
E27 Other disorders of adrenal gland
0.818 0.181 0.000
M33 Dermatopolymyositis
0.818 0.182 0.000
M75.0 Adhesive capsulitis of shoulder
0.817 0.183 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.815 0.185 0.000
N17 Acute renal failure
0.815 0.185 0.000
X20-X29 Contact with venomous animals and plants
0.815 0.185 0.000
E89.0 Postprocedural hypothyroidism
0.814 0.186 0.000
N80 Endometriosis
0.814 0.186 0.000
M24.5 Contracture of joint
0.813 0.186 0.000
D04 Carcinoma in situ of skin
0.812 0.188 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.812 0.188 0.000
S20-S29 Injuries to the thorax
0.810 0.190 0.000
W20-W49 Exposure to inanimate mechanical forces
0.810 0.190 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.810 0.190 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.810 0.190 0.000
F03 Unspecified dementia
0.808 0.192 0.000
Y40 Systemic antibiotics
0.808 0.192 0.000
Chapter VI Diseases of the nervous system
0.805 0.195 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.803 0.197 0.000
I78 Diseases of capillaries
0.802 0.198 0.000
N94.0 Mittelschmerz
0.800 0.200 0.000
S10-S19 Injuries to the neck
0.798 0.202 0.000
S50-S59 Injuries to the elbow and forearm
0.797 0.203 0.000
N20.0 Calculus of kidney
0.796 0.204 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
M25.5 Pain in joint
0.795 0.205 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.793 0.206 0.000
I45 Other conduction disorders
0.793 0.207 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.793 0.207 0.000
H53.1 Subjective visual disturbances
0.792 0.208 0.000
M13.98 Arthritis, unspecified (Other)
0.791 0.209 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.791 0.209 0.000
C71 Malignant neoplasm of brain
0.789 0.211 0.000
M91-M94 Chondropathies
0.789 0.211 0.000
H53.8 Other visual disturbances
0.787 0.213 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.787 0.213 0.000
F80-F89 Disorders of psychological development
0.786 0.213 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.786 0.214 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.784 0.215 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.784 0.216 0.000
E23.0 Hypopituitarism
0.784 0.216 0.000
M20 Acquired deformities of fingers and toes
0.783 0.217 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.782 0.218 0.000
X60-X84 Intentional self-harm
0.781 0.219 0.000
N13 Obstructive and reflux uropathy
0.781 0.219 0.000
C15-C26 Malignant neoplasms of digestive organs
0.780 0.220 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.780 0.220 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.779 0.221 0.000
N97.9 Female infertility, unspecified
0.778 0.222 0.000
C43 Malignant melanoma of skin
0.777 0.223 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.777 0.223 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.776 0.224 0.000
Y42.7 Androgens and anabolic congeners
0.775 0.225 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.774 0.226 0.000
E06 Thyroiditis
0.773 0.226 0.000
M77 Other enthesopathies
0.773 0.227 0.000
M25.3 Other instability of joint
0.773 0.227 0.000
N64 Other disorders of breast
0.773 0.227 0.000
T79-T79 Certain early complications of trauma
0.773 0.227 0.000
N21 Calculus of lower urinary tract
0.772 0.228 0.000
M05 Seropositive rheumatoid arthritis
0.772 0.228 0.000
M85 Other disorders of bone density and structure
0.772 0.228 0.000
S70 Superficial injury of hip and thigh
0.771 0.229 0.000
D48.5 Skin
0.769 0.230 0.000
M25.46 Effusion of joint (Lower leg)
0.769 0.231 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.769 0.231 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
S01.5 Open wound of lip and oral cavity
0.765 0.235 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.764 0.236 0.000
N25-N29 Other disorders of kidney and ureter
0.764 0.236 0.000
E20 Hypoparathyroidism
0.764 0.236 0.000
I49 Other cardiac arrhythmias
0.763 0.237 0.000
D41.0 Kidney
0.762 0.238 0.000
N92.3 Ovulation bleeding
0.761 0.239 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.761 0.239 0.000
N92.4 Excessive bleeding in the premenopausal period
0.760 0.240 0.000
Y57 Other and unspecified drugs and medicaments
0.759 0.240 0.000
D06 Carcinoma in situ of cervix uteri
0.759 0.241 0.000
S02 Fracture of skull and facial bones
0.759 0.241 0.000
M76 Enthesopathies of lower limb, excluding foot
0.758 0.242 0.000
S06.5 Traumatic subdural haemorrhage
0.758 0.242 0.000
M25.56 Pain in joint (Lower leg)
0.757 0.243 0.000
E34 Other endocrine disorders
0.757 0.243 0.000
Chapter X Diseases of the respiratory system
0.756 0.244 0.000
M00-M03 Infectious arthropathies
0.755 0.245 0.000
I07 Rheumatic tricuspid valve diseases
0.755 0.245 0.000
V80-V89 Other land transport accidents
0.755 0.245 0.000
I42 Cardiomyopathy
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.754 0.246 0.000
M20.5 Other deformities of toe(s) (acquired)
0.753 0.247 0.000
W00-W19 Falls
0.752 0.248 0.000
M14 Arthropathies in other diseases classified elsewhere
0.751 0.249 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.750 0.250 0.000
H55-H59 Other disorders of eye and adnexa
0.749 0.251 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.749 0.251 0.000
N20.9 Urinary calculus, unspecified
0.748 0.252 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.747 0.253 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.747 0.253 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.745 0.255 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.744 0.256 0.000
N11 Chronic tubulo-interstitial nephritis
0.743 0.257 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.743 0.257 0.000
N20.2 Calculus of kidney with calculus of ureter
0.742 0.258 0.000
E83 Disorders of mineral metabolism
0.741 0.259 0.000
M13.0 Polyarthritis, unspecified
0.741 0.259 0.000
I20.9 Angina pectoris, unspecified
0.740 0.260 0.000
Chapter I Certain infectious and parasitic diseases
0.739 0.261 0.000
C09 Malignant neoplasm of tonsil
0.738 0.262 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.738 0.262 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
E40-E46 Malnutrition
0.734 0.266 0.000
C73 Malignant neoplasm of thyroid gland
0.734 0.266 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.734 0.266 0.000
M25.84 Other specified joint disorders (Hand)
0.733 0.267 0.000
N91 Absent, scanty and rare menstruation
0.733 0.267 0.000
D48.0 Bone and articular cartilage
0.731 0.268 0.000
E74 Other disorders of carbohydrate metabolism
0.729 0.271 0.000
F31.9 Bipolar affective disorder, unspecified
0.729 0.271 0.000
S67 Crushing injury of wrist and hand
0.728 0.272 0.000
E22 Hyperfunction of pituitary gland
0.727 0.273 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.725 0.274 0.000
M13.93 Arthritis, unspecified (Forearm)
0.725 0.275 0.000
M24.0 Loose body in joint
0.725 0.275 0.000
F42 Obsessive-compulsive disorder
0.725 0.275 0.000
M25.83 Other specified joint disorders (Forearm)
0.725 0.275 0.000
I25.5 Ischaemic cardiomyopathy
0.725 0.275 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.725 0.275 0.000
N17.9 Acute renal failure, unspecified
0.725 0.275 0.000
M75.2 Bicipital tendinitis
0.724 0.276 0.000
H53.2 Diplopia
0.723 0.277 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.723 0.277 0.000
N99-N99 Other disorders of the genitourinary system
0.723 0.277 0.000
T39.1 4-Aminophenol derivatives
0.722 0.278 0.000
I71.0 Dissection of aorta [any part]
0.721 0.279 0.000
E66 Obesity
0.720 0.280 0.000
D04.7 Skin of lower limb, including hip
0.720 0.280 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.719 0.281 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
J09-J18 Influenza and pneumonia
0.719 0.281 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.718 0.282 0.000
M11 Other crystal arthropathies
0.717 0.283 0.000
F40.2 Specific (isolated) phobias
0.717 0.283 0.000
M67 Other disorders of synovium and tendon
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.716 0.283 0.000
F01 Vascular dementia
0.716 0.284 0.000
I49.8 Other specified cardiac arrhythmias
0.716 0.284 0.000
N97.1 Female infertility of tubal origin
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
L40-L45 Papulosquamous disorders
0.716 0.284 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.715 0.284 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.715 0.284 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.715 0.284 0.000
N80.3 Endometriosis of pelvic peritoneum
0.715 0.285 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.715 0.285 0.000
F00 Dementia in Alzheimer's disease
0.714 0.286 0.000
F99-F99 Unspecified mental disorder
0.714 0.286 0.000
M25.9 Joint disorder, unspecified
0.714 0.286 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.714 0.286 0.000
F48 Other neurotic disorders
0.713 0.286 0.000
F44 Dissociative [conversion] disorders
0.713 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.711 0.288 0.000
G90-G99 Other disorders of the nervous system
0.711 0.289 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.711 0.289 0.000
I22 Subsequent myocardial infarction
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.710 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.708 0.292 0.000
E32 Diseases of thymus
0.708 0.292 0.000
E31 Polyglandular dysfunction
0.708 0.292 0.000
E30 Disorders of puberty, not elsewhere classified
0.708 0.292 0.000
E26 Hyperaldosteronism
0.708 0.292 0.000
E25 Adrenogenital disorders
0.708 0.292 0.000
E24 Cushing's syndrome
0.708 0.292 0.000
S65 Injury of blood vessels at wrist and hand level
0.708 0.292 0.000
F41.8 Other specified anxiety disorders
0.708 0.292 0.000
F41.3 Other mixed anxiety disorders
0.708 0.292 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.708 0.292 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.292 0.000
M72 Fibroblastic disorders
0.707 0.293 0.000
C44.1 Skin of eyelid, including canthus
0.707 0.293 0.000
S01.2 Open wound of nose
0.707 0.293 0.000
I07.1 Tricuspid insufficiency
0.707 0.293 0.000
I25.6 Silent myocardial ischaemia
0.707 0.293 0.000
I25.4 Coronary artery aneurysm
0.707 0.293 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.707 0.293 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.706 0.294 0.000
F38 Other mood [affective] disorders
0.706 0.294 0.000
F34 Persistent mood [affective] disorders
0.706 0.294 0.000
F30 Manic episode
0.706 0.294 0.000
F39 Unspecified mood [affective] disorder
0.706 0.294 0.000
N64.1 Fat necrosis of breast
0.706 0.294 0.000
F41.1 Generalised anxiety disorder
0.704 0.296 0.000
S20 Superficial injury of thorax
0.703 0.297 0.000
I20.8 Other forms of angina pectoris
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.703 0.297 0.000
M24.26 Disorder of ligament (Lower leg)
0.703 0.297 0.000
E21.0 Primary hyperparathyroidism
0.703 0.297 0.000
I25.3 Aneurysm of heart
0.702 0.298 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
M25.2 Flail joint
0.701 0.299 0.000
M25.1 Fistula of joint
0.701 0.299 0.000
M25.0 Haemarthrosis
0.701 0.299 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
Y00-Y09 Assault
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X10-X19 Contact with heat and hot substances
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V40-V49 Car occupant injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
E89.2 Postprocedural hypoparathyroidism
0.700 0.300 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.700 0.300 0.000
I70 Atherosclerosis
0.699 0.300 0.000
D48.7 Other specified sites
0.699 0.301 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.699 0.301 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.699 0.301 0.000
X23 Contact with hornets, wasps and bees
0.699 0.301 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.698 0.301 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.698 0.302 0.000
M24.51 Contracture of joint (Shoulder region)
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.302 0.000
F43.1 Posttraumatic stress disorder
0.697 0.303 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.697 0.303 0.000
I45.9 Conduction disorder, unspecified
0.697 0.303 0.000
N98 Complications associated with artificial fertilisation
0.696 0.303 0.000
N82 Fistulae involving female genital tract
0.696 0.303 0.000
N96 Habitual aborter
0.696 0.303 0.000
C01 Malignant neoplasm of base of tongue
0.696 0.304 0.000
C44.8 Overlapping lesion of skin
0.696 0.304 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.696 0.304 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.696 0.304 0.000
H53.0 Amblyopia ex anopsia
0.695 0.305 0.000
Y40.0 Penicillins
0.694 0.305 0.000
N94.5 Secondary dysmenorrhoea
0.694 0.306 0.000
N94.4 Primary dysmenorrhoea
0.694 0.306 0.000
N94.2 Vaginismus
0.694 0.306 0.000
N80.1 Endometriosis of ovary
0.694 0.306 0.000
M13.8 Other specified arthritis
0.694 0.306 0.000
M13.1 Monoarthritis, not elsewhere classified
0.694 0.306 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.694 0.306 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.694 0.306 0.000
M47 Spondylosis
0.692 0.308 0.000
S01.9 Open wound of head, part unspecified
0.691 0.309 0.000
F60-F69 Disorders of adult personality and behaviour
0.691 0.309 0.000
E28 Ovarian dysfunction
0.691 0.309 0.000
M33.1 Other dermatomyositis
0.691 0.309 0.000
S71 Open wound of hip and thigh
0.690 0.310 0.000
I45.3 Trifascicular block
0.690 0.310 0.000
D03 Melanoma in situ
0.689 0.311 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.689 0.311 0.000
L40 Psoriasis
0.689 0.311 0.000
D43.0 Brain, supratentorial
0.688 0.311 0.000
E73 Lactose intolerance
0.688 0.312 0.000
I74 Arterial embolism and thrombosis
0.688 0.312 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.688 0.312 0.000
N85.4 Malposition of uterus
0.687 0.313 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.687 0.313 0.000
N15 Other renal tubulo-interstitial diseases
0.687 0.313 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.687 0.313 0.000
M84 Disorders of continuity of bone
0.687 0.313 0.000
M07 Psoriatic and enteropathic arthropathies
0.687 0.313 0.000
C51-C58 Malignant neoplasms of female genital organs
0.687 0.313 0.000
M71 Other bursopathies
0.687 0.313 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
S06.2 Diffuse brain injury
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.686 0.314 0.000
Y58 Bacterial vaccines
0.686 0.314 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.686 0.314 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.686 0.314 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.686 0.314 0.000
Y48 Anaesthetics and therapeutic gases
0.686 0.314 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.686 0.314 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.686 0.314 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.686 0.314 0.000
M24.9 Joint derangement, unspecified
0.685 0.315 0.000
M24.7 Protrusio acetabuli
0.685 0.315 0.000
M24.6 Ankylosis of joint
0.685 0.315 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.685 0.315 0.000
F43.0 Acute stress reaction
0.685 0.315 0.000
N89.5 Stricture and atresia of vagina
0.685 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
M10 Gout
0.684 0.316 0.000
G20-G26 Extrapyramidal and movement disorders
0.684 0.316 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.684 0.316 0.000
S64.3 Injury of digital nerve of thumb
0.683 0.317 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.683 0.317 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.683 0.317 0.000
F33.8 Other recurrent depressive disorders
0.682 0.318 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.682 0.318 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.682 0.318 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.682 0.318 0.000
S61.7 Multiple open wounds of wrist and hand
0.682 0.318 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.682 0.318 0.000
S06.0 Concussion
0.682 0.318 0.000
C71.1 Frontal lobe
0.681 0.319 0.000
F43.2 Adjustment disorders
0.681 0.319 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.680 0.320 0.000
E85 Amyloidosis
0.680 0.320 0.000
E84 Cystic fibrosis
0.680 0.320 0.000
E79 Disorders of purine and pyrimidine metabolism
0.680 0.320 0.000
E77 Disorders of glycoprotein metabolism
0.680 0.320 0.000
E76 Disorders of glycosaminoglycan metabolism
0.680 0.320 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.680 0.320 0.000
E72 Other disorders of amino-acid metabolism
0.680 0.320 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.680 0.320 0.000
E70 Disorders of aromatic amino-acid metabolism
0.680 0.320 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.680 0.320 0.000
C21 Malignant neoplasm of anus and anal canal
0.680 0.320 0.000
N62 Hypertrophy of breast
0.680 0.320 0.000
H57 Other disorders of eye and adnexa
0.680 0.320 0.000
M75.8 Other shoulder lesions
0.679 0.321 0.000
M75.9 Shoulder lesion, unspecified
0.679 0.321 0.000
M85.8 Other specified disorders of bone density and structure
0.678 0.322 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.677 0.323 0.000
F02 Dementia in other diseases classified elsewhere
0.677 0.323 0.000
F09 Unspecified organic or symptomatic mental disorder
0.677 0.323 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.677 0.323 0.000
M24.23 Disorder of ligament (Forearm)
0.677 0.323 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.677 0.323 0.000
D48.4 Peritoneum
0.677 0.323 0.000
D48.3 Retroperitoneum
0.677 0.323 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.677 0.323 0.000
S05 Injury of eye and orbit
0.677 0.323 0.000
M43 Other deforming dorsopathies
0.677 0.323 0.000
M48 Other spondylopathies
0.676 0.324 0.000
Y44 Agents primarily affecting blood constituents
0.676 0.324 0.000
D37.7 Other digestive organs
0.675 0.325 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.675 0.325 0.000
M66 Spontaneous rupture of synovium and tendon
0.675 0.325 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.673 0.326 0.000
E66.9 Obesity, unspecified
0.673 0.327 0.000
N13.8 Other obstructive and reflux uropathy
0.672 0.328 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
M25.7 Osteophyte
0.671 0.329 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.671 0.329 0.000
E00 Congenital iodine-deficiency syndrome
0.671 0.329 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.671 0.329 0.000
M70.6 Trochanteric bursitis
0.671 0.329 0.000
M21.2 Flexion deformity
0.670 0.330 0.000
S60 Superficial injury of wrist and hand
0.670 0.330 0.000
E83.5 Disorders of calcium metabolism
0.670 0.330 0.000
M25.47 Effusion of joint (Ankle and foot)
0.669 0.331 0.000
S06.4 Epidural haemorrhage
0.668 0.331 0.000
M31 Other necrotising vasculopathies
0.668 0.331 0.000
Y52.1 Calcium-channel blockers
0.668 0.331 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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