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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116431701
log Bayes Factor = 16.2425
Chromosome 7   position 151,413,973  (GRCh37) Explore rs116431701 on Ensembl!
Variant rs116431701 is part of Cluster X0085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
K29 Gastritis and duodenitis
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
K21 Gastro-oesophageal reflux disease
0.990 0.010 0.000
Chapter II Neoplasms
0.990 0.010 0.000
M45-M49 Spondylopathies
0.989 0.011 0.000
J30-J39 Other diseases of upper respiratory tract
0.989 0.011 0.000
S00-S09 Injuries to the head
0.989 0.011 0.000
M15-M19 Arthrosis
0.988 0.012 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.984 0.016 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
M48 Other spondylopathies
0.973 0.027 0.000
M19 Other arthrosis
0.969 0.031 0.000
K22 Other diseases of oesophagus
0.964 0.036 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.961 0.039 0.000
K29.5 Chronic gastritis, unspecified
0.961 0.039 0.000
M48.0 Spinal stenosis
0.961 0.039 0.000
C15-C26 Malignant neoplasms of digestive organs
0.960 0.040 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.956 0.044 0.000
M19.9 Arthrosis, unspecified
0.955 0.045 0.000
M48.06 Spinal stenosis (Lumbar region)
0.951 0.049 0.000
Chapter V Mental and behavioural disorders
0.949 0.051 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.946 0.054 0.000
Z72 Problems related to lifestyle
0.943 0.057 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.940 0.060 0.000
J20-J22 Other acute lower respiratory infections
0.937 0.063 0.000
C20 Malignant neoplasm of rectum
0.931 0.069 0.000
S06 Intracranial injury
0.927 0.073 0.000
Chapter XX External causes of morbidity and mortality
0.925 0.075 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
Z72.1 Alcohol use
0.918 0.082 0.000
M70-M79 Other soft tissue disorders
0.914 0.086 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.911 0.089 0.000
J34 Other disorders of nose and nasal sinuses
0.910 0.090 0.000
S20-S29 Injuries to the thorax
0.909 0.091 0.000
J22 Unspecified acute lower respiratory infection
0.893 0.107 0.000
J90-J94 Other diseases of pleura
0.890 0.110 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.889 0.111 0.000
M18 Arthrosis of first carpometacarpal joint
0.885 0.115 0.000
K02 Dental caries
0.884 0.116 0.000
S01 Open wound of head
0.884 0.116 0.000
M40-M43 Deforming dorsopathies
0.882 0.118 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.882 0.118 0.000
C79 Secondary malignant neoplasm of other sites
0.877 0.123 0.000
Chapter VIII Diseases of the ear and mastoid process
0.876 0.124 0.000
S90-S99 Injuries to the ankle and foot
0.876 0.124 0.000
M17 Gonarthrosis [arthrosis of knee]
0.874 0.126 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.873 0.127 0.000
M47 Spondylosis
0.871 0.129 0.000
J35 Chronic diseases of tonsils and adenoids
0.870 0.130 0.000
K29.4 Chronic atrophic gastritis
0.868 0.132 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.866 0.134 0.000
G90-G99 Other disorders of the nervous system
0.866 0.134 0.000
Z74 Problems related to care-provider dependency
0.865 0.134 0.000
K22.7 Barrett's oesophagus
0.865 0.135 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.863 0.137 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.860 0.140 0.000
K29.6 Other gastritis
0.858 0.142 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.855 0.145 0.000
S40-S49 Injuries to the shoulder and upper arm
0.855 0.145 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.852 0.148 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.850 0.150 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.847 0.153 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.846 0.154 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.846 0.154 0.000
M65-M68 Disorders of synovium and tendon
0.846 0.154 0.000
S80-S89 Injuries to the knee and lower leg
0.846 0.154 0.000
K02.9 Dental caries, unspecified
0.845 0.155 0.000
K29.2 Alcoholic gastritis
0.838 0.162 0.000
M05-M14 Inflammatory polyarthropathies
0.833 0.167 0.000
K29.1 Other acute gastritis
0.829 0.171 0.000
K50-K52 Noninfective enteritis and colitis
0.828 0.172 0.000
F30-F39 Mood [affective] disorders
0.828 0.172 0.000
J34.2 Deviated nasal septum
0.827 0.173 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.823 0.177 0.000
K22.2 Oesophageal obstruction
0.822 0.178 0.000
J33 Nasal polyp
0.821 0.179 0.000
C64-C68 Malignant neoplasms of urinary tract
0.819 0.181 0.000
M17.0 Primary gonarthrosis, bilateral
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
S00 Superficial injury of head
0.815 0.185 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.815 0.185 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.812 0.188 0.000
K29.0 Acute haemorrhagic gastritis
0.810 0.190 0.000
K22.1 Ulcer of oesophagus
0.807 0.193 0.000
Z13 Special screening examination for other diseases and disorders
0.799 0.201 0.000
J90 Pleural effusion, not elsewhere classified
0.799 0.201 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.799 0.201 0.000
S01.0 Open wound of scalp
0.799 0.201 0.000
E70-E90 Metabolic disorders
0.794 0.206 0.000
G93 Other disorders of brain
0.794 0.206 0.000
W00-W19 Falls
0.792 0.208 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.792 0.208 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.792 0.208 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.788 0.212 0.000
M43 Other deforming dorsopathies
0.788 0.212 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.788 0.212 0.000
K29.3 Chronic superficial gastritis
0.788 0.212 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.787 0.213 0.000
W20-W49 Exposure to inanimate mechanical forces
0.787 0.213 0.000
J35.1 Hypertrophy of tonsils
0.787 0.213 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.787 0.213 0.000
C16 Malignant neoplasm of stomach
0.786 0.214 0.000
S02 Fracture of skull and facial bones
0.782 0.218 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.782 0.218 0.000
S09 Other and unspecified injuries of head
0.782 0.218 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.782 0.218 0.000
Z74.0 Reduced mobility
0.781 0.219 0.000
J32 Chronic sinusitis
0.781 0.219 0.000
M67 Other disorders of synovium and tendon
0.777 0.223 0.000
S27 Injury of other and unspecified intrathoracic organs
0.776 0.223 0.000
K50 Crohn's disease [regional enteritis]
0.775 0.225 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.772 0.228 0.000
C78.2 Secondary malignant neoplasm of pleura
0.769 0.231 0.000
T66-T78 Other and unspecified effects of external causes
0.769 0.231 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.769 0.231 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.767 0.233 0.000
Chapter IX Diseases of the circulatory system
0.767 0.233 0.000
F31 Bipolar affective disorder
0.765 0.235 0.000
J00-J06 Acute upper respiratory infections
0.765 0.235 0.000
K65-K67 Diseases of peritoneum
0.764 0.235 0.000
Z71.8 Other specified counselling
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.763 0.237 0.000
S06.5 Traumatic subdural haemorrhage
0.763 0.237 0.000
H65-H75 Diseases of middle ear and mastoid
0.762 0.238 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.761 0.239 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.758 0.242 0.000
J39 Other diseases of upper respiratory tract
0.758 0.242 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
J92 Pleural plaque
0.756 0.244 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.755 0.245 0.000
M50-M54 Other dorsopathies
0.754 0.246 0.000
K22.0 Achalasia of cardia
0.754 0.246 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.753 0.246 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.752 0.248 0.000
K31 Other diseases of stomach and duodenum
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
M80-M85 Disorders of bone density and structure
0.749 0.251 0.000
S06.4 Epidural haemorrhage
0.748 0.252 0.000
T79-T79 Certain early complications of trauma
0.748 0.252 0.000
K26 Duodenal ulcer
0.747 0.253 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.747 0.253 0.000
K12 Stomatitis and related lesions
0.747 0.253 0.000
G20-G26 Extrapyramidal and movement disorders
0.747 0.253 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.746 0.254 0.000
K09 Cysts of oral region, not elsewhere classified
0.746 0.254 0.000
M79.0 Rheumatism, unspecified
0.746 0.254 0.000
Z13.9 Special screening examination, unspecified
0.745 0.255 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.743 0.257 0.000
M17.9 Gonarthrosis, unspecified
0.743 0.257 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.742 0.258 0.000
C60-C63 Malignant neoplasms of male genital organs
0.742 0.258 0.000
S91 Open wound of ankle and foot
0.741 0.259 0.000
K13 Other diseases of lip and oral mucosa
0.739 0.261 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.738 0.262 0.000
M47.8 Other spondylosis
0.738 0.262 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.737 0.263 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.737 0.263 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.734 0.266 0.000
O60-O75 Complications of labour and delivery
0.734 0.266 0.000
Z75 Problems related to medical facilities and other health care
0.734 0.266 0.000
K22.5 Diverticulum of oesophagus, acquired
0.734 0.266 0.000
Z57 Occupational exposure to risk-factors
0.734 0.266 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.733 0.267 0.000
S70-S79 Injuries to the hip and thigh
0.732 0.267 0.000
K10 Other diseases of jaws
0.731 0.269 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.731 0.269 0.000
K70-K77 Diseases of liver
0.731 0.269 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.731 0.269 0.000
J95-J99 Other diseases of the respiratory system
0.729 0.271 0.000
S06.3 Focal brain injury
0.729 0.271 0.000
G30-G32 Other degenerative diseases of the nervous system
0.729 0.271 0.000
M19.94 Arthrosis, unspecified (Hand)
0.727 0.272 0.000
C80 Malignant neoplasm without specification of site
0.727 0.273 0.000
S06.2 Diffuse brain injury
0.726 0.273 0.000
Chapter XXII Codes for special purposes
0.726 0.274 0.000
K25 Gastric ulcer
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.722 0.277 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.720 0.280 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.720 0.280 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.720 0.280 0.000
J33.8 Other polyp of sinus
0.720 0.280 0.000
J30 Vasomotor and allergic rhinitis
0.719 0.281 0.000
Z73 Problems related to life-management difficulty
0.718 0.282 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.718 0.282 0.000
J60-J70 Lung diseases due to external agents
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
K29.9 Gastroduodenitis, unspecified
0.714 0.285 0.000
S92 Fracture of foot, except ankle
0.713 0.287 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.712 0.288 0.000
K22.8 Other specified diseases of oesophagus
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
M79.8 Other specified soft tissue disorders
0.710 0.290 0.000
M49 Spondylopathies in diseases classified elsewhere
0.709 0.290 0.000
M45 Ankylosing spondylitis
0.709 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.290 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.709 0.291 0.000
J37 Chronic laryngitis and laryngotracheitis
0.709 0.291 0.000
S08 Traumatic amputation of part of head
0.709 0.291 0.000
S07 Crushing injury of head
0.709 0.291 0.000
S05 Injury of eye and orbit
0.709 0.291 0.000
S04 Injury of cranial nerves
0.709 0.291 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.709 0.291 0.000
S42 Fracture of shoulder and upper arm
0.709 0.291 0.000
M15 Polyarthrosis
0.708 0.292 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.708 0.292 0.000
K04 Diseases of pulp and periapical tissues
0.708 0.292 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.708 0.292 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.707 0.293 0.000
T18 Foreign body in alimentary tract
0.707 0.293 0.000
G91 Hydrocephalus
0.707 0.293 0.000
D00-D09 In situ neoplasms
0.707 0.293 0.000
F60-F69 Disorders of adult personality and behaviour
0.706 0.294 0.000
K22.9 Disease of oesophagus, unspecified
0.705 0.295 0.000
Z76 Persons encountering health services in other circumstances
0.705 0.295 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.705 0.295 0.000
V10-V19 Pedal cyclist injured in transport accident
0.704 0.296 0.000
K05 Gingivitis and periodontal diseases
0.703 0.297 0.000
K27 Peptic ulcer, site unspecified
0.703 0.297 0.000
M13 Other arthritis
0.703 0.297 0.000
G93.3 Postviral fatigue syndrome
0.703 0.297 0.000
M48.09 Spinal stenosis (Site unspecified)
0.702 0.298 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.298 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.298 0.000
T17 Foreign body in respiratory tract
0.701 0.299 0.000
H60-H62 Diseases of external ear
0.700 0.299 0.000
K40-K46 Hernia
0.700 0.300 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.699 0.301 0.000
K50.1 Crohn's disease of large intestine
0.699 0.301 0.000
Z60 Problems related to social environment
0.699 0.301 0.000
J38.3 Other diseases of vocal cords
0.699 0.301 0.000
S20 Superficial injury of thorax
0.698 0.302 0.000
C78.0 Secondary malignant neoplasm of lung
0.698 0.302 0.000
M48.9 Spondylopathy, unspecified
0.697 0.303 0.000
M48.8 Other specified spondylopathies
0.697 0.303 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.697 0.303 0.000
M48.4 Fatigue fracture of vertebra
0.697 0.303 0.000
M48.3 Traumatic spondylopathy
0.697 0.303 0.000
M48.2 Kissing spine
0.697 0.303 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.697 0.303 0.000
M46 Other inflammatory spondylopathies
0.696 0.304 0.000
F31.9 Bipolar affective disorder, unspecified
0.696 0.304 0.000
J36 Peritonsillar abscess
0.695 0.305 0.000
M19.8 Other specified arthrosis
0.694 0.305 0.000
M19.2 Other secondary arthrosis
0.694 0.305 0.000
M19.1 Posttraumatic arthrosis of other joints
0.694 0.305 0.000
M19.0 Primary arthrosis of other joints
0.694 0.305 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.694 0.306 0.000
M47.9 Spondylosis, unspecified
0.694 0.306 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.694 0.306 0.000
Z92 Personal history of medical treatment
0.694 0.306 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.692 0.308 0.000
K22.3 Perforation of oesophagus
0.691 0.309 0.000
O36 Maternal care for other known or suspected foetal problems
0.690 0.310 0.000
I05-I09 Chronic rheumatic heart diseases
0.690 0.310 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.689 0.311 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.689 0.311 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.689 0.311 0.000
M48.04 Spinal stenosis (Thoracic region)
0.689 0.311 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.689 0.311 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.689 0.311 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.689 0.311 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.688 0.312 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.688 0.312 0.000
C21 Malignant neoplasm of anus and anal canal
0.688 0.312 0.000
C17 Malignant neoplasm of small intestine
0.688 0.312 0.000
C23 Malignant neoplasm of gallbladder
0.688 0.312 0.000
M19.98 Arthrosis, unspecified (Other)
0.687 0.313 0.000
M43.1 Spondylolisthesis
0.687 0.313 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.687 0.313 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.685 0.315 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.685 0.315 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.685 0.315 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.685 0.315 0.000
T82.3 Mechanical complication of other vascular grafts
0.685 0.315 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.685 0.315 0.000
T82.1 Mechanical complication of cardiac electronic device
0.685 0.315 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.685 0.315 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.685 0.315 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.685 0.315 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.685 0.315 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.685 0.315 0.000
C34 Malignant neoplasm of bronchus and lung
0.684 0.316 0.000
J09-J18 Influenza and pneumonia
0.684 0.316 0.000
E65-E68 Obesity and other hyperalimentation
0.682 0.318 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.682 0.318 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.682 0.318 0.000
S27.0 Traumatic pneumothorax
0.681 0.318 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.681 0.319 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.680 0.320 0.000
F99-F99 Unspecified mental disorder
0.680 0.320 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.680 0.320 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000
F70-F79 Mental retardation
0.680 0.320 0.000
S01.2 Open wound of nose
0.680 0.320 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.679 0.321 0.000
Z80 Family history of malignant neoplasm
0.678 0.322 0.000
M67.8 Other specified disorders of synovium and tendon
0.678 0.322 0.000
E50-E64 Other nutritional deficiencies
0.677 0.323 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
I60-I69 Cerebrovascular diseases
0.676 0.324 0.000
Z72.9 Problem related to lifestyle, unspecified
0.676 0.324 0.000
Z72.8 Other problems related to lifestyle
0.676 0.324 0.000
Z72.6 Gambling and betting
0.676 0.324 0.000
Z72.5 High-risk sexual behaviour
0.676 0.324 0.000
Z72.4 Inappropriate diet and eating habits
0.676 0.324 0.000
Z72.3 Lack of physical exercise
0.676 0.324 0.000
Z72.2 Drug use
0.676 0.324 0.000
S50-S59 Injuries to the elbow and forearm
0.676 0.324 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.676 0.324 0.000
C16.9 Stomach, unspecified
0.676 0.324 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.675 0.325 0.000
K03 Other diseases of hard tissues of teeth
0.674 0.326 0.000
K00 Disorders of tooth development and eruption
0.674 0.326 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.674 0.326 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.328 0.000
J21 Acute bronchiolitis
0.672 0.328 0.000
J20 Acute bronchitis
0.672 0.328 0.000
Z93 Artificial opening status
0.672 0.328 0.000
K07 Dentofacial anomalies [including malocclusion]
0.671 0.328 0.000
E86 Volume depletion
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.671 0.328 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.671 0.329 0.000
W44 Foreign body entering into or through eye or natural orifice
0.671 0.329 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.671 0.329 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.670 0.330 0.000
S40 Superficial injury of shoulder and upper arm
0.670 0.330 0.000
M75 Shoulder lesions
0.669 0.331 0.000
M72 Fibroblastic disorders
0.668 0.332 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.668 0.332 0.000
S01.8 Open wound of other parts of head
0.667 0.332 0.000
S22.4 Multiple fractures of ribs
0.667 0.333 0.000
O63 Long labour
0.666 0.334 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.665 0.335 0.000
S06.9 Intracranial injury, unspecified
0.665 0.335 0.000
S06.8 Other intracranial injuries
0.665 0.335 0.000
S06.7 Intracranial injury with prolonged coma
0.665 0.335 0.000
S06.1 Traumatic cerebral oedema
0.665 0.335 0.000
S06.0 Concussion
0.665 0.335 0.000
G96 Other disorders of central nervous system
0.663 0.337 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.663 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.663 0.337 0.000
Y10-Y34 Event of undetermined intent
0.663 0.337 0.000
Y00-Y09 Assault
0.663 0.337 0.000
X85-X99 Assault
0.663 0.337 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.663 0.337 0.000
X50-X57 Overexertion, travel and privation
0.663 0.337 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.663 0.337 0.000
X30-X39 Exposure to forces of nature
0.663 0.337 0.000
X20-X29 Contact with venomous animals and plants
0.663 0.337 0.000
X10-X19 Contact with heat and hot substances
0.663 0.337 0.000
X00-X09 Exposure to smoke, fire and flames
0.663 0.337 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.663 0.337 0.000
W75-W84 Other accidental threats to breathing
0.663 0.337 0.000
W65-W74 Accidental drowning and submersion
0.663 0.337 0.000
W50-W64 Exposure to animate mechanical forces
0.663 0.337 0.000
V98-V99 Other and unspecified transport accidents
0.663 0.337 0.000
V95-V97 Air and space transport accidents
0.663 0.337 0.000
V90-V94 Water transport accidents
0.663 0.337 0.000
V80-V89 Other land transport accidents
0.663 0.337 0.000
V70-V79 Bus occupant injured in transport accident
0.663 0.337 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.663 0.337 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.663 0.337 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.663 0.337 0.000
V01-V09 Pedestrian injured in transport accident
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.663 0.337 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.662 0.338 0.000
S81 Open wound of lower leg
0.662 0.338 0.000
S82 Fracture of lower leg, including ankle
0.661 0.339 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.660 0.340 0.000
H66 Suppurative and unspecified otitis media
0.660 0.340 0.000
C25 Malignant neoplasm of pancreas
0.659 0.341 0.000
M54 Dorsalgia
0.659 0.341 0.000
M11 Other crystal arthropathies
0.658 0.341 0.000
S01.9 Open wound of head, part unspecified
0.657 0.342 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.657 0.343 0.000
M41 Scoliosis
0.656 0.344 0.000
T88.4 Failed or difficult intubation
0.656 0.344 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.656 0.344 0.000
T92 Sequelae of injuries of upper limb
0.655 0.345 0.000
E20-E35 Disorders of other endocrine glands
0.655 0.345 0.000
M76 Enthesopathies of lower limb, excluding foot
0.655 0.345 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.655 0.345 0.000
M71 Other bursopathies
0.655 0.345 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.655 0.345 0.000
S89 Other and unspecified injuries of lower leg
0.654 0.346 0.000
M47.2 Other spondylosis with radiculopathy
0.653 0.347 0.000
H90-H95 Other disorders of ear
0.653 0.347 0.000
M77 Other enthesopathies
0.653 0.347 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.652 0.348 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.652 0.348 0.000
S29 Other and unspecified injuries of thorax
0.652 0.348 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.652 0.348 0.000
S26 Injury of heart
0.652 0.348 0.000
S25 Injury of blood vessels of thorax
0.652 0.348 0.000
S24 Injury of nerves and spinal cord at thorax level
0.652 0.348 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.652 0.348 0.000
S21 Open wound of thorax
0.652 0.348 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.651 0.349 0.000
M79.6 Pain in limb
0.651 0.349 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.650 0.350 0.000
T70 Effects of air pressure and water pressure
0.650 0.350 0.000
C34.1 Upper lobe, bronchus or lung
0.647 0.353 0.000
Q60-Q64 Congenital malformations of the urinary system
0.646 0.353 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.646 0.354 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.646 0.354 0.000
K11 Diseases of salivary glands
0.645 0.354 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.645 0.355 0.000
K35-K38 Diseases of appendix
0.644 0.355 0.000
S91.3 Open wound of other parts of foot
0.644 0.356 0.000
K29.7 Gastritis, unspecified
0.644 0.356 0.000
S60-S69 Injuries to the wrist and hand
0.644 0.356 0.000
X60-X84 Intentional self-harm
0.643 0.357 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.643 0.357 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.643 0.357 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.642 0.358 0.000
C15 Malignant neoplasm of oesophagus
0.642 0.358 0.000
J33.0 Polyp of nasal cavity
0.641 0.359 0.000
S00.8 Superficial injury of other parts of head
0.641 0.359 0.000
K50.0 Crohn's disease of small intestine
0.641 0.359 0.000
M43.0 Spondylolysis
0.640 0.360 0.000
J91 Pleural effusion in conditions classified elsewhere
0.640 0.360 0.000
F33 Recurrent depressive disorder
0.639 0.361 0.000
Z57.2 Occupational exposure to dust
0.639 0.361 0.000
Z72.0 Tobacco use
0.638 0.362 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.638 0.362 0.000
J94 Other pleural conditions
0.638 0.362 0.000
C22.0 Liver cell carcinoma
0.638 0.362 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.637 0.362 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.637 0.362 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.637 0.362 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.637 0.362 0.000
T39.0 Salicylates
0.635 0.365 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.634 0.365 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.634 0.365 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.634 0.365 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.634 0.365 0.000
G93.6 Cerebral oedema
0.634 0.366 0.000
K02.8 Other dental caries
0.634 0.366 0.000
K02.5 Caries with pulp exposure
0.634 0.366 0.000
K02.4 Odontoclasia
0.634 0.366 0.000
K02.3 Arrested dental caries
0.634 0.366 0.000
K02.2 Caries of cementum
0.634 0.366 0.000
K02.1 Caries of dentin
0.634 0.366 0.000
K02.0 Caries limited to enamel
0.634 0.366 0.000
S01.7 Multiple open wounds of head
0.634 0.366 0.000
S01.4 Open wound of cheek and temporomandibular area
0.634 0.366 0.000
S01.3 Open wound of ear
0.634 0.366 0.000
S01.1 Open wound of eyelid and periocular area
0.634 0.366 0.000
S09.9 Unspecified injury of head
0.633 0.367 0.000
Z35 Supervision of high-risk pregnancy
0.633 0.367 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.633 0.367 0.000
J92.9 Pleural plaque without asbestos
0.633 0.367 0.000
W10 Fall on and from stairs and steps
0.633 0.367 0.000
M42 Spinal osteochondrosis
0.632 0.368 0.000
M40 Kyphosis and lordosis
0.632 0.368 0.000
O85-O92 Complications predominantly related to the puerperium
0.632 0.368 0.000
S00.1 Contusion of eyelid and periocular area
0.632 0.368 0.000
O80-O84 Delivery
0.631 0.369 0.000
Z96 Presence of other functional implants
0.630 0.370 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.630 0.370 0.000
J81 Pulmonary oedema
0.629 0.371 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.629 0.371 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.629 0.371 0.000
C79.6 Secondary malignant neoplasm of ovary
0.629 0.371 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.629 0.371 0.000
C79.2 Secondary malignant neoplasm of skin
0.629 0.371 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.629 0.371 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.629 0.371 0.000
W19 Unspecified fall
0.629 0.371 0.000
S99 Other and unspecified injuries of ankle and foot
0.628 0.372 0.000
S98 Traumatic amputation of ankle and foot
0.628 0.372 0.000
S97 Crushing injury of ankle and foot
0.628 0.372 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.628 0.372 0.000
S95 Injury of blood vessels at ankle and foot level
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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