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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79015790
log Bayes Factor = 14.8688
Chromosome 12   position 128,700,249  (GRCh37) Explore rs79015790 on Ensembl!
Variant rs79015790 is part of Cluster X0213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R30-R39 Symptoms and signs involving the urinary system
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
R35 Polyuria
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.989 0.011 0.000
R39 Other symptoms and signs involving the urinary system
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.988 0.012 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.983 0.017 0.000
E10-E14 Diabetes mellitus
0.981 0.019 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.976 0.024 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
C79 Secondary malignant neoplasm of other sites
0.965 0.035 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.959 0.041 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.958 0.042 0.000
D00-D09 In situ neoplasms
0.955 0.045 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.955 0.045 0.000
R11 Nausea and vomiting
0.952 0.048 0.000
M70-M79 Other soft tissue disorders
0.946 0.054 0.000
M10 Gout
0.943 0.057 0.000
E10 Insulin-dependent diabetes mellitus
0.938 0.062 0.000
Chapter XIV Diseases of the genitourinary system
0.938 0.062 0.000
R00 Abnormalities of heart beat
0.934 0.066 0.000
E11 Non-insulin-dependent diabetes mellitus
0.928 0.072 0.000
M10.9 Gout, unspecified
0.926 0.074 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.919 0.081 0.000
Chapter VII Diseases of the eye and adnexa
0.918 0.082 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.914 0.086 0.000
M10.99 Gout, unspecified (Site unspecified)
0.912 0.088 0.000
Chapter XXI Factors influencing health status and contact with health services
0.912 0.088 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.910 0.090 0.000
C15-C26 Malignant neoplasms of digestive organs
0.902 0.098 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.897 0.103 0.000
R79 Other abnormal findings of blood chemistry
0.895 0.105 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.891 0.109 0.000
R94 Abnormal results of function studies
0.891 0.109 0.000
S20-S29 Injuries to the thorax
0.890 0.110 0.000
D05 Carcinoma in situ of breast
0.889 0.111 0.000
N10-N16 Renal tubulo-interstitial diseases
0.886 0.114 0.000
R07 Pain in throat and chest
0.883 0.117 0.000
C77.3 Axillary and upper limb lymph nodes
0.873 0.127 0.000
R00.2 Palpitations
0.872 0.128 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.871 0.129 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
S00-S09 Injuries to the head
0.870 0.130 0.000
R07.3 Other chest pain
0.864 0.136 0.000
M75 Shoulder lesions
0.864 0.136 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.858 0.142 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.858 0.142 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.851 0.149 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.850 0.150 0.000
Chapter I Certain infectious and parasitic diseases
0.849 0.151 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.847 0.153 0.000
Chapter X Diseases of the respiratory system
0.847 0.153 0.000
C77.2 Intra-abdominal lymph nodes
0.844 0.156 0.000
N13 Obstructive and reflux uropathy
0.843 0.157 0.000
Z51 Other medical care
0.841 0.159 0.000
W00-W19 Falls
0.840 0.160 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.836 0.164 0.000
N40-N51 Diseases of male genital organs
0.835 0.165 0.000
R94.5 Abnormal results of liver function studies
0.834 0.166 0.000
D70 Agranulocytosis
0.830 0.170 0.000
R33 Retention of urine
0.830 0.170 0.000
R00.0 Tachycardia, unspecified
0.826 0.174 0.000
R73 Elevated blood glucose level
0.826 0.174 0.000
M40-M43 Deforming dorsopathies
0.824 0.176 0.000
H30-H36 Disorders of choroid and retina
0.823 0.177 0.000
Z51.3 Blood transfusion without reported diagnosis
0.822 0.178 0.000
E11.3 With ophthalmic complications
0.820 0.180 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.819 0.181 0.000
Chapter V Mental and behavioural disorders
0.818 0.182 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.816 0.184 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.816 0.184 0.000
Y43 Primarily systemic agents
0.815 0.185 0.000
D10-D36 Benign neoplasms
0.815 0.185 0.000
R04 Haemorrhage from respiratory passages
0.815 0.185 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.815 0.185 0.000
C77.9 Lymph node, unspecified
0.814 0.186 0.000
S60-S69 Injuries to the wrist and hand
0.813 0.187 0.000
M80-M85 Disorders of bone density and structure
0.812 0.188 0.000
R14 Flatulence and related conditions
0.812 0.188 0.000
D69 Purpura and other haemorrhagic conditions
0.808 0.192 0.000
D05.1 Intraductal carcinoma in situ
0.808 0.192 0.000
M75.1 Rotator cuff syndrome
0.805 0.195 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.803 0.197 0.000
J20-J22 Other acute lower respiratory infections
0.801 0.199 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.801 0.199 0.000
R25 Abnormal involuntary movements
0.799 0.201 0.000
M50-M54 Other dorsopathies
0.798 0.202 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.797 0.203 0.000
R30 Pain associated with micturition
0.795 0.205 0.000
E65-E68 Obesity and other hyperalimentation
0.794 0.206 0.000
E20-E35 Disorders of other endocrine glands
0.793 0.207 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.793 0.207 0.000
C77.5 Intrapelvic lymph nodes
0.789 0.210 0.000
E10.1 With ketoacidosis
0.789 0.211 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.787 0.213 0.000
N17-N19 Renal failure
0.786 0.214 0.000
E10.3 With ophthalmic complications
0.785 0.215 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.785 0.215 0.000
M91-M94 Chondropathies
0.785 0.215 0.000
H43-H45 Disorders of vitreous body and globe
0.783 0.217 0.000
E10.5 With peripheral circulatory complications
0.780 0.220 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.780 0.220 0.000
N99-N99 Other disorders of the genitourinary system
0.780 0.220 0.000
Chapter VI Diseases of the nervous system
0.780 0.220 0.000
Chapter VIII Diseases of the ear and mastoid process
0.778 0.222 0.000
C15 Malignant neoplasm of oesophagus
0.778 0.222 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.778 0.222 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.775 0.224 0.000
E10.9 Without complications
0.775 0.225 0.000
J09-J18 Influenza and pneumonia
0.775 0.225 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.773 0.227 0.000
M45-M49 Spondylopathies
0.772 0.228 0.000
Z45 Adjustment and management of implanted device
0.769 0.231 0.000
D69.6 Thrombocytopenia, unspecified
0.768 0.232 0.000
J22 Unspecified acute lower respiratory infection
0.768 0.232 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.765 0.235 0.000
J90-J94 Other diseases of pleura
0.764 0.236 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.764 0.236 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.763 0.237 0.000
D22 Melanocytic naevi
0.763 0.237 0.000
R02 Gangrene, not elsewhere classified
0.762 0.237 0.000
E11.4 With neurological complications
0.762 0.238 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.761 0.239 0.000
S50-S59 Injuries to the elbow and forearm
0.758 0.242 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.757 0.243 0.000
Y43.3 Other antineoplastic drugs
0.757 0.243 0.000
C77.4 Inguinal and lower limb lymph nodes
0.756 0.244 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.753 0.247 0.000
R04.0 Epistaxis
0.750 0.250 0.000
O00-O08 Pregnancy with abortive outcome
0.750 0.250 0.000
W19 Unspecified fall
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.749 0.251 0.000
Z51.5 Palliative care
0.747 0.253 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.746 0.254 0.000
Z45.2 Adjustment and management of vascular access device
0.746 0.254 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.745 0.255 0.000
C25 Malignant neoplasm of pancreas
0.744 0.256 0.000
M11 Other crystal arthropathies
0.743 0.257 0.000
D06 Carcinoma in situ of cervix uteri
0.743 0.257 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.741 0.258 0.000
Z42 Follow-up care involving plastic surgery
0.741 0.259 0.000
C77.0 Lymph nodes of head, face and neck
0.741 0.259 0.000
R27 Other lack of coordination
0.741 0.259 0.000
M76 Enthesopathies of lower limb, excluding foot
0.739 0.261 0.000
E11.2 With renal complications
0.738 0.262 0.000
H36 Retinal disorders in diseases classified elsewhere
0.737 0.263 0.000
H55-H59 Other disorders of eye and adnexa
0.735 0.265 0.000
M13 Other arthritis
0.733 0.267 0.000
E11.9 Without complications
0.732 0.268 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.268 0.000
N43 Hydrocele and spermatocele
0.731 0.269 0.000
R73.9 Hyperglycaemia, unspecified
0.730 0.270 0.000
R26 Abnormalities of gait and mobility
0.730 0.270 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.729 0.271 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.729 0.271 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.728 0.272 0.000
R82 Other abnormal findings in urine
0.726 0.274 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.725 0.275 0.000
C77.1 Intrathoracic lymph nodes
0.724 0.276 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.724 0.276 0.000
E14 Unspecified diabetes mellitus
0.722 0.278 0.000
J18 Pneumonia, organism unspecified
0.722 0.278 0.000
A30-A49 Other bacterial diseases
0.721 0.279 0.000
S20 Superficial injury of thorax
0.720 0.280 0.000
C80 Malignant neoplasm without specification of site
0.720 0.280 0.000
T66-T78 Other and unspecified effects of external causes
0.720 0.280 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.720 0.280 0.000
R31 Unspecified haematuria
0.720 0.280 0.000
E50-E64 Other nutritional deficiencies
0.719 0.281 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.718 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R36 Urethral discharge
0.717 0.283 0.000
R34 Anuria and oliguria
0.717 0.283 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.717 0.283 0.000
R17 Unspecified jaundice
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.715 0.285 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
B95-B98 Bacterial, viral and other infectious agents
0.712 0.288 0.000
S80-S89 Injuries to the knee and lower leg
0.712 0.288 0.000
R05 Cough
0.712 0.288 0.000
D04 Carcinoma in situ of skin
0.711 0.288 0.000
E40-E46 Malnutrition
0.711 0.288 0.000
D22.5 Melanocytic naevi of trunk
0.711 0.289 0.000
S02 Fracture of skull and facial bones
0.710 0.290 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.710 0.290 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.291 0.000
R39.2 Extrarenal uraemia
0.708 0.291 0.000
R39.0 Extravasation of urine
0.708 0.291 0.000
T33-T35 Frostbite
0.708 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.291 0.000
S10-S19 Injuries to the neck
0.708 0.291 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
D80-D89 Certain disorders involving the immune mechanism
0.707 0.293 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.703 0.297 0.000
M51 Other intervertebral disk disorders
0.702 0.298 0.000
C18 Malignant neoplasm of colon
0.702 0.298 0.000
N42 Other disorders of prostate
0.701 0.299 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.701 0.299 0.000
C77.8 Lymph nodes of multiple regions
0.700 0.300 0.000
N50 Other disorders of male genital organs
0.700 0.300 0.000
M77 Other enthesopathies
0.700 0.300 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.699 0.301 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.699 0.301 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.697 0.303 0.000
Z51.0 Radiotherapy session
0.696 0.304 0.000
N17 Acute renal failure
0.695 0.304 0.000
N13.3 Other and unspecified hydronephrosis
0.695 0.305 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.695 0.305 0.000
M14 Arthropathies in other diseases classified elsewhere
0.694 0.306 0.000
M12 Other specific arthropathies
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
M05 Seropositive rheumatoid arthritis
0.694 0.306 0.000
X60-X84 Intentional self-harm
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V40-V49 Car occupant injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
V10-V19 Pedal cyclist injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.692 0.308 0.000
C79.6 Secondary malignant neoplasm of ovary
0.692 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.692 0.308 0.000
C79.2 Secondary malignant neoplasm of skin
0.692 0.308 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.692 0.308 0.000
S00 Superficial injury of head
0.692 0.308 0.000
W19.2 School, other institution and public administrative area
0.691 0.309 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.691 0.309 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.690 0.310 0.000
C16 Malignant neoplasm of stomach
0.690 0.310 0.000
R87 Abnormal findings in specimens from female genital organs
0.689 0.311 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.689 0.311 0.000
D60-D64 Aplastic and other anaemias
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.688 0.312 0.000
O00 Ectopic pregnancy
0.687 0.313 0.000
D03 Melanoma in situ
0.687 0.313 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.687 0.313 0.000
R77 Other abnormalities of plasma proteins
0.687 0.313 0.000
R76 Other abnormal immunological findings in serum
0.687 0.313 0.000
R74 Abnormal serum enzyme levels
0.687 0.313 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.687 0.313 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.687 0.313 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.687 0.313 0.000
R71 Abnormality of red blood cells
0.687 0.313 0.000
Z51.1 Chemotherapy session for neoplasm
0.686 0.314 0.000
H43 Disorders of vitreous body
0.686 0.314 0.000
D09 Carcinoma in situ of other and unspecified sites
0.685 0.315 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.685 0.315 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.685 0.315 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.685 0.315 0.000
N13.8 Other obstructive and reflux uropathy
0.685 0.315 0.000
N13.4 Hydroureter
0.684 0.316 0.000
M43 Other deforming dorsopathies
0.682 0.318 0.000
D73 Diseases of spleen
0.682 0.318 0.000
J18.1 Lobar pneumonia, unspecified
0.681 0.319 0.000
N30-N39 Other diseases of urinary system
0.681 0.319 0.000
M79.8 Other specified soft tissue disorders
0.681 0.319 0.000
H10-H13 Disorders of conjunctiva
0.681 0.319 0.000
C15.5 Lower third of oesophagus
0.679 0.321 0.000
J90 Pleural effusion, not elsewhere classified
0.679 0.321 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.678 0.322 0.000
M71 Other bursopathies
0.678 0.322 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.678 0.322 0.000
M10.4 Other secondary gout
0.676 0.323 0.000
M10.3 Gout due to impairment of renal function
0.676 0.323 0.000
M10.2 Drug-induced gout
0.676 0.323 0.000
M10.1 Lead-induced gout
0.676 0.323 0.000
M10.0 Idiopathic gout
0.676 0.323 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.676 0.324 0.000
R01 Cardiac murmurs and other cardiac sounds
0.675 0.324 0.000
H36.0 Diabetic retinopathy
0.676 0.324 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
A00-A09 Intestinal infectious diseases
0.673 0.327 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.673 0.327 0.000
C20 Malignant neoplasm of rectum
0.673 0.327 0.000
E10.8 With unspecified complications
0.672 0.327 0.000
E10.7 With multiple complications
0.672 0.327 0.000
E10.6 With other specified complications
0.672 0.327 0.000
E10.4 With neurological complications
0.672 0.327 0.000
E10.2 With renal complications
0.672 0.327 0.000
E10.0 With coma
0.672 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.672 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.328 0.000
D36 Benign neoplasm of other and unspecified sites
0.670 0.330 0.000
R80 Isolated proteinuria
0.669 0.331 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.667 0.333 0.000
E16 Other disorders of pancreatic internal secretion
0.667 0.333 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.667 0.333 0.000
S01 Open wound of head
0.666 0.334 0.000
Z52 Donors of organs and tissues
0.666 0.334 0.000
E11.8 With unspecified complications
0.665 0.335 0.000
E11.7 With multiple complications
0.665 0.335 0.000
E11.6 With other specified complications
0.665 0.335 0.000
E11.1 With ketoacidosis
0.665 0.335 0.000
E11.0 With coma
0.665 0.335 0.000
M10.98 Gout, unspecified (Other)
0.664 0.336 0.000
M10.96 Gout, unspecified (Lower leg)
0.664 0.336 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.664 0.336 0.000
M10.94 Gout, unspecified (Hand)
0.664 0.336 0.000
M10.93 Gout, unspecified (Forearm)
0.664 0.336 0.000
M10.92 Gout, unspecified (Upper arm)
0.664 0.336 0.000
M10.91 Gout, unspecified (Shoulder region)
0.664 0.336 0.000
M10.90 Gout, unspecified (Multiple sites)
0.664 0.336 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
C51-C58 Malignant neoplasms of female genital organs
0.661 0.338 0.000
N25-N29 Other disorders of kidney and ureter
0.661 0.339 0.000
E00-E07 Disorders of thyroid gland
0.659 0.341 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.659 0.341 0.000
T87 Complications peculiar to reattachment and amputation
0.659 0.341 0.000
T86 Failure and rejection of transplanted organs and tissues
0.659 0.341 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.658 0.342 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.658 0.342 0.000
R09.1 Pleurisy
0.658 0.342 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.658 0.342 0.000
H33 Retinal detachments and breaks
0.658 0.342 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
N43.3 Hydrocele, unspecified
0.656 0.344 0.000
H40-H42 Glaucoma
0.656 0.344 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.656 0.344 0.000
F60-F69 Disorders of adult personality and behaviour
0.656 0.344 0.000
M06 Other rheumatoid arthritis
0.655 0.345 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.653 0.347 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.653 0.347 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.653 0.347 0.000
E66 Obesity
0.652 0.348 0.000
M75.3 Calcific tendinitis of shoulder
0.652 0.348 0.000
E11.5 With peripheral circulatory complications
0.651 0.349 0.000
M79.6 Pain in limb
0.649 0.351 0.000
R30.0 Dysuria
0.649 0.351 0.000
Y40 Systemic antibiotics
0.648 0.351 0.000
Y95 Nosocomial condition
0.648 0.352 0.000
G35 Multiple sclerosis
0.648 0.352 0.000
D75 Other diseases of blood and blood-forming organs
0.647 0.353 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.647 0.353 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.647 0.353 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.647 0.353 0.000
C21 Malignant neoplasm of anus and anal canal
0.647 0.353 0.000
C17 Malignant neoplasm of small intestine
0.647 0.353 0.000
C23 Malignant neoplasm of gallbladder
0.647 0.353 0.000
D45 Polycythaemia vera
0.646 0.354 0.000
R25.2 Cramp and spasm
0.646 0.354 0.000
N45 Orchitis and epididymitis
0.645 0.355 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.645 0.355 0.000
C01 Malignant neoplasm of base of tongue
0.645 0.355 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.644 0.356 0.000
A41 Other septicaemia
0.644 0.356 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.644 0.356 0.000
Y59 Other and unspecified vaccines and biological substances
0.643 0.357 0.000
Y58 Bacterial vaccines
0.643 0.357 0.000
Y57 Other and unspecified drugs and medicaments
0.643 0.357 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.643 0.357 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.643 0.357 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.643 0.357 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.643 0.357 0.000
Y52 Agents primarily affecting the cardiovascular system
0.643 0.357 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.643 0.357 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.643 0.357 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
Y48 Anaesthetics and therapeutic gases
0.643 0.357 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.643 0.357 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.643 0.357 0.000
Y44 Agents primarily affecting blood constituents
0.643 0.357 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.643 0.357 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.643 0.357 0.000
O00.1 Tubal pregnancy
0.642 0.358 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.642 0.358 0.000
R79.0 Abnormal level of blood mineral
0.642 0.358 0.000
Z75 Problems related to medical facilities and other health care
0.642 0.358 0.000
S09 Other and unspecified injuries of head
0.642 0.358 0.000
R25.1 Tremor, unspecified
0.641 0.359 0.000
M75.4 Impingement syndrome of shoulder
0.640 0.360 0.000
S22.2 Fracture of sternum
0.639 0.361 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.639 0.361 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.639 0.361 0.000
D74 Methaemoglobinaemia
0.639 0.361 0.000
D72 Other disorders of white blood cells
0.639 0.361 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.639 0.361 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.639 0.361 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.639 0.361 0.000
R94.7 Abnormal results of other endocrine function studies
0.639 0.361 0.000
R94.6 Abnormal results of thyroid function studies
0.639 0.361 0.000
R94.4 Abnormal results of kidney function studies
0.639 0.361 0.000
R94.2 Abnormal results of pulmonary function studies
0.639 0.361 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.639 0.361 0.000
R94.0 Abnormal results of function studies of central nervous system
0.639 0.361 0.000
E70-E90 Metabolic disorders
0.639 0.361 0.000
S29 Other and unspecified injuries of thorax
0.638 0.362 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.638 0.362 0.000
S27 Injury of other and unspecified intrathoracic organs
0.638 0.362 0.000
S26 Injury of heart
0.638 0.362 0.000
S25 Injury of blood vessels of thorax
0.638 0.362 0.000
S24 Injury of nerves and spinal cord at thorax level
0.638 0.362 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.638 0.362 0.000
S21 Open wound of thorax
0.638 0.362 0.000
D05.7 Other carcinoma in situ of breast
0.637 0.362 0.000
D05.0 Lobular carcinoma in situ
0.637 0.362 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.637 0.363 0.000
C50-C50 Malignant neoplasm of breast
0.635 0.364 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.635 0.365 0.000
N15 Other renal tubulo-interstitial diseases
0.635 0.365 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.635 0.365 0.000
N11 Chronic tubulo-interstitial nephritis
0.635 0.365 0.000
N10 Acute tubulo-interstitial nephritis
0.635 0.365 0.000
S22.0 Fracture of thoracic vertebra
0.635 0.365 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.635 0.365 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.634 0.366 0.000
S06 Intracranial injury
0.633 0.366 0.000
R07.1 Chest pain on breathing
0.633 0.367 0.000
M51.2 Other specified intervertebral disk displacement
0.633 0.367 0.000
D11 Benign neoplasm of major salivary glands
0.632 0.368 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.631 0.369 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.631 0.369 0.000
N17.9 Acute renal failure, unspecified
0.631 0.369 0.000
M46 Other inflammatory spondylopathies
0.629 0.371 0.000
S42 Fracture of shoulder and upper arm
0.628 0.372 0.000
H53-H54 Visual disturbances and blindness
0.627 0.373 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.626 0.373 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.625 0.375 0.000
N60-N64 Disorders of breast
0.625 0.375 0.000
D68 Other coagulation defects
0.625 0.375 0.000
D67 Hereditary factor IX deficiency
0.625 0.375 0.000
D66 Hereditary factor VIII deficiency
0.625 0.375 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.625 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.624 0.375 0.000
Q80-Q89 Other congenital malformations
0.624 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.624 0.375 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.624 0.375 0.000
Q35-Q37 Cleft lip and cleft palate
0.624 0.375 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.624 0.375 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.624 0.375 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.624 0.376 0.000
S08 Traumatic amputation of part of head
0.624 0.376 0.000
S07 Crushing injury of head
0.624 0.376 0.000
S05 Injury of eye and orbit
0.624 0.376 0.000
S04 Injury of cranial nerves
0.624 0.376 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.624 0.376 0.000
R94.3 Abnormal results of cardiovascular function studies
0.623 0.376 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.621 0.379 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.621 0.379 0.000
M41 Scoliosis
0.621 0.379 0.000
D07.1 Vulva
0.619 0.381 0.000
M75.8 Other shoulder lesions
0.619 0.381 0.000
M75.9 Shoulder lesion, unspecified
0.619 0.381 0.000
M75.2 Bicipital tendinitis
0.619 0.381 0.000
M90 Osteopathies in diseases classified elsewhere
0.619 0.381 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.617 0.383 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.617 0.383 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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