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Diagnostic term associations

Self-Reported Statistics (SRS)

Motor neurone disease
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs17391905 lBF = 1.10853   Chr1 : 51,546,140
0.000 0.666 0.334
rs1335532 lBF = 1.24728   Chr1 : 117,100,957
0.000 0.853 0.146
rs2078371 lBF = 9.94154   Chr1 : 115,677,183
0.146 0.854 0.000
rs12134493 lBF = 9.98151   Chr1 : 115,677,946
0.133 0.867 0.000
rs11808092 lBF = 0.403864   Chr1 : 93,073,228
0.130 0.870 0.000
rs1323292 lBF = 4.36444   Chr1 : 192,541,021
0.125 0.875 0.000
rs2300747 lBF = 0.965441   Chr1 : 117,104,215
0.000 0.894 0.106
rs2816316 lBF = 3.85015   Chr1 : 192,536,813
0.101 0.898 0.000
rs61819372 lBF = 8.34272   Chr1 : 114,072,110
0.082 0.918 0.000
rs6025 lBF = 137.395   Chr1 : 169,519,049
0.078 0.922 0.000
rs74434895 lBF = 7.60443   Chr1 : 113,934,072
0.059 0.941 0.000
rs2025934 lBF = 0.134611   Chr1 : 193,734,900
0.044 0.956 0.000
rs16830359 lBF = 0.312238   Chr1 : 43,596,384
0.035 0.965 0.000
rs28359571 lBF = 0.207734   Chr1 : 230,881,876
0.035 0.965 0.000
rs6671847 lBF = 4.27981   Chr1 : 161,478,810
0.034 0.966 0.000
rs7552722 lBF = 0.153422   Chr1 : 115,921,355
0.026 0.973 0.000
rs76264265 lBF = 0.203023   Chr1 : 37,309,390
0.024 0.975 0.000
rs78516619 lBF = 29.5761   Chr1 : 168,889,373
0.023 0.976 0.000
rs233100 lBF = -0.0119404   Chr1 : 85,772,009
0.000 0.980 0.020
rs11810217 lBF = -0.0415324   Chr1 : 93,148,377
0.018 0.982 0.000
rs10863790 lBF = 0.107629   Chr1 : 209,988,047
0.014 0.986 0.000
rs12023377 lBF = 0.00723121   Chr1 : 34,151,260
0.000 0.988 0.012
rs12074980 lBF = 0.28319   Chr1 : 184,636,516
0.012 0.988 0.000
rs576523 lBF = 0.121195   Chr1 : 160,746,076
0.000 0.988 0.011
rs2235371 lBF = 0.0782527   Chr1 : 209,964,080
0.010 0.990 0.000
rs6025 lBF = 138.002   Chr1 : 169,519,049
0.000 0.991 0.009
rs115083581 lBF = 0.776479   Chr1 : 36,376,992
0.009 0.991 0.000
rs10218452 lBF = 21.2722   Chr1 : 3,075,597
0.008 0.992 0.000
rs12025416 lBF = 0.178249   Chr1 : 117,038,287
0.000 0.992 0.008
rs115699453 lBF = 0.0893218   Chr1 : 156,827,703
0.007 0.993 0.000
rs11264799 lBF = 0.364324   Chr1 : 157,670,757
0.000 0.994 0.006
rs61759167 lBF = 20.0985   Chr1 : 3,091,587
0.006 0.994 0.000
rs801112 lBF = 0.1326   Chr1 : 228,996,622
0.005 0.995 0.000
rs12043302 lBF = -0.0451786   Chr1 : 7,055,024
0.000 0.995 0.005
rs3761959 lBF = 3.6385   Chr1 : 157,669,278
0.000 0.995 0.005
rs7528684 lBF = 3.57745   Chr1 : 157,670,816
0.000 0.996 0.004
rs4657172 lBF = -0.0668094   Chr1 : 162,179,632
0.000 0.996 0.004
rs12723025 lBF = 0.00018029   Chr1 : 223,977,519
0.003 0.996 0.000
rs140505938 lBF = 0.0054031   Chr1 : 150,031,490
0.003 0.997 0.000
rs7535475 lBF = 0.18172   Chr1 : 161,463,587
0.003 0.997 0.000
rs76759221 lBF = 0.00969793   Chr1 : 239,716,845
0.000 0.997 0.003
rs115446434 lBF = 0.08494   Chr1 : 33,531,257
0.003 0.997 0.000
rs12073359 lBF = 0.00164809   Chr1 : 150,008,790
0.003 0.997 0.000
rs17129289 lBF = 0.0302201   Chr1 : 84,232,748
0.003 0.997 0.000
rs77737545 lBF = -0.0000994   Chr1 : 241,976,607
0.003 0.997 0.000
rs3091242 lBF = 0.0173114   Chr1 : 25,674,785
0.003 0.997 0.000
rs114218990 lBF = 0.0294484   Chr1 : 48,501,029
0.003 0.997 0.000
rs139898146 lBF = 1.71837   Chr1 : 25,600,747
0.003 0.997 0.000
rs6604026 lBF = -0.125854   Chr1 : 93,303,603
0.003 0.997 0.000
rs2860031 lBF = -0.130852   Chr1 : 30,525,714
0.000 0.997 0.002
rs41314643 lBF = 0.109102   Chr1 : 183,255,908
0.002 0.998 0.000
rs10927875 lBF = -0.100745   Chr1 : 16,299,312
0.002 0.998 0.000
rs181704351 lBF = 0.0375677   Chr1 : 70,147,866
0.002 0.998 0.000
rs1539454 lBF = -0.00823916   Chr1 : 219,983,780
0.002 0.998 0.000
rs77271258 lBF = 0.0751991   Chr1 : 218,056,637
0.002 0.998 0.000
rs12091371 lBF = -0.00790955   Chr1 : 240,605,052
0.000 0.998 0.002
rs61780598 lBF = 0.162641   Chr1 : 53,131,770
0.002 0.998 0.000
rs28485419 lBF = -0.10278   Chr1 : 102,495,987
0.000 0.998 0.002
rs12027135 lBF = 0.0595384   Chr1 : 25,775,733
0.002 0.998 0.000
rs1043879 lBF = 0.0110433   Chr1 : 25,570,081
0.000 0.998 0.002
rs195204 lBF = -0.125376   Chr1 : 115,734,091
0.000 0.998 0.002
rs148553336 lBF = 0.0353268   Chr1 : 196,613,173
0.002 0.998 0.000
rs10903129 lBF = 0.0103705   Chr1 : 25,768,937
0.002 0.998 0.000
rs12039519 lBF = 0.0621349   Chr1 : 161,953,400
0.000 0.998 0.002
rs72722108 lBF = -0.00990576   Chr1 : 95,589,180
0.001 0.998 0.000
rs606149 lBF = 0.164763   Chr1 : 193,921,548
0.001 0.998 0.000
rs7527798 lBF = -0.10269   Chr1 : 207,872,290
0.000 0.998 0.002
rs2476601 lBF = 160.809   Chr1 : 114,377,568
0.002 0.998 0.000
rs6679677 lBF = 158.346   Chr1 : 114,303,808
0.002 0.998 0.000
rs2391388 lBF = -0.22324   Chr1 : 95,485,825
0.000 0.998 0.002
rs78049208 lBF = 0.183046   Chr1 : 218,613,620
0.001 0.998 0.000
rs12085006 lBF = -0.0626253   Chr1 : 11,958,723
0.001 0.998 0.000
rs490647 lBF = -0.170323   Chr1 : 37,242,743
0.001 0.998 0.000
rs1704198 lBF = 0.0380655   Chr1 : 213,910,494
0.001 0.998 0.000
rs138157192 lBF = 0.00821674   Chr1 : 192,043,457
0.001 0.998 0.000
rs7551641 lBF = 0.0149307   Chr1 : 120,017,927
0.001 0.998 0.000
rs12725009 lBF = 1.05384   Chr1 : 3,413,997
0.001 0.998 0.000
rs10158481 lBF = -0.112867   Chr1 : 25,497,792
0.001 0.998 0.000
rs17131547 lBF = -0.00426151   Chr1 : 92,211,020
0.000 0.999 0.001
rs586178 lBF = 0.166141   Chr1 : 25,747,230
0.001 0.999 0.000
rs6675668 lBF = -0.181744   Chr1 : 95,515,637
0.001 0.999 0.000
rs116276575 lBF = 0.043815   Chr1 : 59,207,425
0.001 0.999 0.000
rs3753573 lBF = 0.0149941   Chr1 : 185,014,002
0.001 0.999 0.000
rs12754465 lBF = -0.0517471   Chr1 : 74,675,210
0.000 0.999 0.001
rs1635501 lBF = -0.108993   Chr1 : 242,040,775
0.001 0.999 0.000
rs438034 lBF = -0.19367   Chr1 : 214,830,617
0.001 0.999 0.000
rs2359952 lBF = 1.18942   Chr1 : 198,656,407
0.000 0.999 0.001
rs6677208 lBF = 0.00293455   Chr1 : 239,601,969
0.001 0.999 0.000
rs116527709 lBF = -0.0121015   Chr1 : 87,398,673
0.001 0.999 0.000
rs7552806 lBF = 0.0186826   Chr1 : 204,784,018
0.001 0.999 0.000
rs7522462 lBF = 2.96342   Chr1 : 200,881,595
0.000 0.999 0.001
rs10799445 lBF = -0.218479   Chr1 : 227,911,883
0.000 0.999 0.001
rs115445154 lBF = 0.095767   Chr1 : 81,921,812
0.001 0.999 0.000
rs17018311 lBF = -0.051986   Chr1 : 212,155,008
0.001 0.999 0.000
rs12084151 lBF = -0.123598   Chr1 : 238,409,445
0.001 0.999 0.000
rs35730213 lBF = 3.48896   Chr1 : 200,874,229
0.000 0.999 0.001
rs1998013 lBF = 1.44147   Chr1 : 55,958,030
0.001 0.999 0.001
rs191506206 lBF = 0.00747635   Chr1 : 191,990,367
0.001 0.999 0.000
rs4846835 lBF = -0.120107   Chr1 : 230,281,156
0.000 0.999 0.001
rs2651899 lBF = 10.0309   Chr1 : 3,083,712
0.001 0.999 0.000
rs11579060 lBF = -0.0866081   Chr1 : 160,606,092
0.001 0.999 0.000
rs116716590 lBF = 0.00467809   Chr1 : 230,953,151
0.001 0.999 0.000
rs181870845 lBF = 0.00528803   Chr1 : 78,532,565
0.001 0.999 0.000
rs76620758 lBF = 0.00150262   Chr1 : 97,375,844
0.001 0.999 0.000
rs2476601 lBF = 159.383   Chr1 : 114,377,568
0.000 0.999 0.001
rs75722236 lBF = 0.0476109   Chr1 : 98,118,470
0.001 0.999 0.000
rs28408478 lBF = 0.226361   Chr1 : 19,287,138
0.001 0.999 0.000
rs191953093 lBF = 0.00300693   Chr1 : 181,006,881
0.000 0.999 0.001
rs6669008 lBF = 0.459779   Chr1 : 114,166,561
0.001 0.999 0.000
rs12067906 lBF = 0.00974118   Chr1 : 192,431,998
0.001 0.999 0.000
rs1948368 lBF = -0.207447   Chr1 : 101,938,477
0.001 0.999 0.000
rs114864186 lBF = 0.0703105   Chr1 : 211,944,094
0.000 0.999 0.001
rs79079833 lBF = 0.00273363   Chr1 : 114,607,364
0.001 0.999 0.000
rs140320399 lBF = -0.0342267   Chr1 : 235,797,345
0.001 0.999 0.000
rs11247594 lBF = -0.178517   Chr1 : 27,067,417
0.001 0.999 0.000
rs192109529 lBF = 0.00197057   Chr1 : 205,679,394
0.001 0.999 0.000
rs61778046 lBF = 6.96338   Chr1 : 22,358,789
0.001 0.999 0.000
rs480745 lBF = 0.00284645   Chr1 : 83,269,970
0.001 0.999 0.000
rs17036023 lBF = 0.00239628   Chr1 : 117,129,711
0.001 0.999 0.000
rs12058524 lBF = 0.00091785   Chr1 : 150,066,384
0.001 0.999 0.000
rs3014707 lBF = 0.00357925   Chr1 : 26,009,459
0.000 0.999 0.001
rs14271 lBF = -0.00119822   Chr1 : 9,789,150
0.001 0.999 0.000
rs35615859 lBF = 0.0274999   Chr1 : 49,057,717
0.001 0.999 0.000
rs11120822 lBF = -0.0433013   Chr1 : 7,113,112
0.000 0.999 0.001
rs10911251 lBF = -0.126807   Chr1 : 183,081,194
0.000 0.999 0.001
rs191448950 lBF = 16.1321   Chr1 : 55,584,844
0.001 0.999 0.000
rs142698760 lBF = 0.0355122   Chr1 : 51,604,266
0.001 0.999 0.000
rs184109064 lBF = 0.0351238   Chr1 : 51,604,367
0.001 0.999 0.000
rs148657146 lBF = 0.0351238   Chr1 : 51,592,400
0.001 0.999 0.000
rs180746259 lBF = 0.0351238   Chr1 : 51,617,510
0.001 0.999 0.000
rs141175086 lBF = 0.00263918   Chr1 : 780,397
0.001 0.999 0.000
rs140743827 lBF = 0.00238417   Chr1 : 164,985,756
0.001 0.999 0.000
rs12239436 lBF = 0.00218319   Chr1 : 55,742,837
0.001 0.999 0.000
rs1168000 lBF = 0.00079237   Chr1 : 62,932,815
0.000 0.999 0.001
rs4839516 lBF = -0.155845   Chr1 : 116,740,450
0.000 0.999 0.001
rs3219090 lBF = 0.41361   Chr1 : 226,564,691
0.001 0.999 0.000
rs187620787 lBF = 0.0336701   Chr1 : 51,595,006
0.001 0.999 0.000
rs16862426 lBF = 0.00121813   Chr1 : 19,321,495
0.001 0.999 0.000
rs1842579 lBF = -0.0800975   Chr1 : 86,289,082
0.000 0.999 0.001
rs138833465 lBF = 0.00094983   Chr1 : 220,584,872
0.001 0.999 0.000
rs181502228 lBF = 0.0009383   Chr1 : 205,509,298
0.000 0.999 0.001
rs12092053 lBF = 0.00090162   Chr1 : 50,607,029
0.001 0.999 0.000
rs6681544 lBF = -0.15683   Chr1 : 82,398,544
0.000 0.999 0.001
rs79990645 lBF = 0.0782451   Chr1 : 42,924,003
0.001 0.999 0.000
rs17094777 lBF = 0.0409325   Chr1 : 74,507,315
0.001 0.999 0.000
rs16849553 lBF = 0.00053492   Chr1 : 229,336,846
0.001 0.999 0.000
rs59905655 lBF = 0.00038713   Chr1 : 16,071,010
0.001 0.999 0.000
rs7554511 lBF = 3.40745   Chr1 : 200,877,562
0.000 0.999 0.001
rs2317230 lBF = 2.16456   Chr1 : 157,674,997
0.000 0.999 0.001
rs10911390 lBF = 0.211291   Chr1 : 183,616,884
0.001 0.999 0.000
rs13373941 lBF = 0.00019376   Chr1 : 239,644,171
0.001 0.999 0.000
rs79969755 lBF = 0.00013018   Chr1 : 240,851,291
0.001 0.999 0.000
rs116540944 lBF = 0.00009963   Chr1 : 37,305,794
0.001 0.999 0.000
rs77653389 lBF = 0.00000605   Chr1 : 37,312,705
0.001 0.999 0.000
rs187464554 lBF = 0   Chr1 : 105,476,854
0.001 0.999 0.001
rs192166173 lBF = 0   Chr1 : 64,162,008
0.001 0.999 0.001
rs6697139 lBF = 0   Chr1 : 161,660,696
0.001 0.999 0.001
rs908327 lBF = 0   Chr1 : 235,092,600
0.001 0.999 0.001
rs11809789 lBF = 0   Chr1 : 82,074,852
0.001 0.999 0.001
rs116647499 lBF = 0   Chr1 : 246,082,884
0.001 0.999 0.001
rs17706439 lBF = 0   Chr1 : 213,855,588
0.001 0.999 0.001
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0.001 0.999 0.001
rs10922104 lBF = 0   Chr1 : 196,687,730
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs7542813 lBF = 0   Chr1 : 245,133,539
0.001 0.999 0.001
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0.001 0.999 0.001
rs11589828 lBF = 0   Chr1 : 232,669,272
0.001 0.999 0.001
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0.001 0.999 0.001
rs6703865 lBF = 0   Chr1 : 169,550,963
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs147410855 lBF = 0   Chr1 : 59,737,892
0.001 0.999 0.001
rs17130643 lBF = 0   Chr1 : 89,341,408
0.001 0.999 0.001
rs181927184 lBF = 0   Chr1 : 25,483,944
0.001 0.999 0.001
rs12739262 lBF = 0   Chr1 : 202,391,743
0.001 0.999 0.001
rs3813948 lBF = 0   Chr1 : 207,269,858
0.001 0.999 0.001
rs182234674 lBF = 0   Chr1 : 214,105,743
0.001 0.999 0.001
rs12046780 lBF = 0   Chr1 : 218,673,593
0.001 0.999 0.001
rs150884133 lBF = 0   Chr1 : 105,471,200
0.001 0.999 0.001
rs3766920 lBF = 0   Chr1 : 154,934,963
0.001 0.999 0.001
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0.001 0.999 0.001
rs181295069 lBF = 0   Chr1 : 226,512,466
0.001 0.999 0.001
rs143083071 lBF = 0   Chr1 : 99,707,754
0.001 0.999 0.001
rs115107872 lBF = 0   Chr1 : 246,077,264
0.001 0.999 0.001
rs144177292 lBF = 0   Chr1 : 201,964,059
0.001 0.999 0.001
rs2501324 lBF = 0   Chr1 : 159,856,429
0.001 0.999 0.001
rs139175374 lBF = 0   Chr1 : 78,209,416
0.001 0.999 0.001
rs11465804 lBF = 0   Chr1 : 67,702,526
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs2642442 lBF = 0   Chr1 : 220,973,563
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs13375391 lBF = -0.00027698   Chr1 : 185,794,883
0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs1101999 lBF = 0.00134967   Chr1 : 158,932,555
0.001 0.999 0.000
rs116133558 lBF = -0.00106438   Chr1 : 203,716,843
0.001 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs16844716 lBF = -0.00125245   Chr1 : 199,356,516
0.001 0.999 0.000
rs1043274 lBF = -0.00142048   Chr1 : 110,042,444
0.001 0.999 0.000
rs79131758 lBF = -0.00483538   Chr1 : 216,969,577
0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.000 0.999 0.000
rs4846033 lBF = -0.00189587   Chr1 : 11,788,564
0.000 0.999 0.001
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0.001 0.999 0.000
rs164898 lBF = -0.146738   Chr1 : 91,569,689
0.000 0.999 0.001
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rs116407893 lBF = -0.0592674   Chr1 : 45,555,700
0.000 0.999 0.000
rs10918270 lBF = -0.0864888   Chr1 : 161,915,501
0.000 0.999 0.000
rs12568266 lBF = -0.0867958   Chr1 : 4,193,551
0.000 0.999 0.000
rs17259784 lBF = -0.0974034   Chr1 : 208,757,586
0.001 0.999 0.000
rs9662633 lBF = -0.10381   Chr1 : 3,649,562
0.000 0.999 0.000
rs1172130 lBF = -0.10827   Chr1 : 205,244,953
0.001 0.999 0.000
rs3123012 lBF = -0.111539   Chr1 : 69,558,139
0.000 0.999 0.000
rs211718 lBF = -0.123597   Chr1 : 76,106,675
0.000 0.999 0.001
rs11587438 lBF = -0.129081   Chr1 : 6,631,431
0.000 0.999 0.001
rs860873 lBF = -0.171599   Chr1 : 95,387,208
0.001 0.999 0.000
rs285480 lBF = -0.189014   Chr1 : 165,403,903
0.000 0.999 0.001
rs4077468 lBF = -0.203094   Chr1 : 205,914,757
0.000 0.999 0.001
rs11121667 lBF = -0.205724   Chr1 : 11,038,476
0.000 0.999 0.001
rs11204538 lBF = -0.241739   Chr1 : 248,046,272
0.000 0.999 0.001
rs61813875 lBF = 45.9167   Chr1 : 152,536,650
0.000 0.999 0.000
rs115725122 lBF = 0.436062   Chr1 : 115,955,917
0.000 0.999 0.000
rs1983546 lBF = 0.21483   Chr1 : 169,446,183
0.000 0.999 0.001
rs2185341 lBF = 0.0569894   Chr1 : 22,725,825
0.000 0.999 0.000
rs116833987 lBF = 0.00216682   Chr1 : 97,606,979
0.000 0.999 0.000
rs12073504 lBF = -0.00319394   Chr1 : 2,452,979
0.000 0.999 0.000
rs1015275 lBF = -0.0199414   Chr1 : 218,670,141
0.000 0.999 0.000
rs11118112 lBF = -0.0208092   Chr1 : 218,673,257
0.000 0.999 0.000
rs6693039 lBF = -0.0220233   Chr1 : 218,654,507
0.000 0.999 0.000
rs527430 lBF = -0.0233664   Chr1 : 47,918,821
0.000 0.999 0.000
rs72738842 lBF = -0.0241256   Chr1 : 218,672,807
0.000 0.999 0.000
rs12039922 lBF = -0.0241256   Chr1 : 218,673,815
0.000 0.999 0.000
rs12025796 lBF = -0.0241256   Chr1 : 218,674,002
0.000 0.999 0.000
rs76574709 lBF = -0.0255784   Chr1 : 12,743,326
0.000 0.999 0.000
rs12040654 lBF = -0.0276815   Chr1 : 218,660,277
0.000 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.