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Diagnostic term associations

Self-Reported Statistics (SRS)

Motor neurone disease
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs78378222 lBF = 4.16698   Chr17 : 7,571,752
0.251 0.749 0.000
rs117611723 lBF = 0.576556   Chr17 : 35,913,589
0.107 0.892 0.000
rs11650106 lBF = 0.672288   Chr17 : 57,850,251
0.000 0.950 0.050
rs1801689 lBF = 2.49991   Chr17 : 64,210,580
0.020 0.979 0.000
rs118155463 lBF = 0.263534   Chr17 : 8,079,842
0.013 0.987 0.000
rs12940923 lBF = 0.225569   Chr17 : 56,369,849
0.000 0.990 0.010
rs1292053 lBF = 0.0132507   Chr17 : 57,963,537
0.008 0.992 0.000
rs3764400 lBF = -0.0398601   Chr17 : 46,123,932
0.007 0.992 0.000
rs9900205 lBF = -0.0870746   Chr17 : 64,715,108
0.007 0.993 0.000
rs6258 lBF = 0.490626   Chr17 : 7,534,678
0.006 0.994 0.000
rs2732703 lBF = 1.20799   Chr17 : 44,353,222
0.000 0.996 0.004
rs7503953 lBF = 0.197986   Chr17 : 6,141,677
0.000 0.996 0.003
rs1051424 lBF = 0.218203   Chr17 : 58,024,324
0.003 0.997 0.000
rs9901225 lBF = 0.0703478   Chr17 : 40,755,811
0.000 0.997 0.003
rs2732614 lBF = 0.749545   Chr17 : 44,364,209
0.000 0.997 0.003
rs35850753 lBF = 1.92608   Chr17 : 7,578,671
0.002 0.998 0.000
rs9910816 lBF = -0.128119   Chr17 : 66,344,703
0.000 0.998 0.002
rs7209700 lBF = 0.314848   Chr17 : 45,351,118
0.002 0.998 0.000
rs71380849 lBF = 0.290932   Chr17 : 72,975,748
0.002 0.998 0.000
rs4144743 lBF = -0.0369039   Chr17 : 45,323,125
0.002 0.998 0.000
rs111433752 lBF = 1.4389   Chr17 : 43,857,989
0.000 0.998 0.002
rs183211 lBF = 0.920565   Chr17 : 44,788,310
0.000 0.998 0.002
rs2072153 lBF = 0.00640451   Chr17 : 47,390,014
0.001 0.998 0.000
rs8072451 lBF = 1.45648   Chr17 : 43,893,716
0.000 0.998 0.001
rs12601558 lBF = -0.069083   Chr17 : 80,179,147
0.000 0.999 0.001
rs11079757 lBF = -0.121908   Chr17 : 45,195,850
0.001 0.999 0.000
rs393152 lBF = 1.75164   Chr17 : 43,719,143
0.000 0.999 0.001
rs9902453 lBF = -0.0534009   Chr17 : 28,349,095
0.000 0.999 0.001
rs199499 lBF = 0.64875   Chr17 : 44,865,498
0.000 0.999 0.001
Affx-13926329 lBF = 1.44101   Chr17 : 43,861,117
0.000 0.999 0.001
rs6761 lBF = 0.117488   Chr17 : 7,417,663
0.001 0.999 0.000
rs12185268 lBF = 1.53498   Chr17 : 43,923,683
0.000 0.999 0.001
rs2942168 lBF = 1.59962   Chr17 : 43,714,850
0.000 0.999 0.001
rs1663189 lBF = 0.114444   Chr17 : 77,889,055
0.000 0.999 0.001
rs111854052 lBF = -0.018658   Chr17 : 62,600,935
0.000 0.999 0.001
rs9895232 lBF = -0.154887   Chr17 : 4,519,139
0.000 0.999 0.001
rs143323161 lBF = 0.00379233   Chr17 : 66,346,556
0.001 0.999 0.000
rs17645023 lBF = -0.112734   Chr17 : 64,917,033
0.001 0.999 0.000
rs17689882 lBF = 1.46437   Chr17 : 43,906,828
0.000 0.999 0.001
rs17607 lBF = 0.127522   Chr17 : 7,484,782
0.001 0.999 0.000
rs17577094 lBF = 1.37915   Chr17 : 44,187,492
0.000 0.999 0.001
rs8081460 lBF = -0.120135   Chr17 : 8,965,272
0.000 0.999 0.001
rs76919247 lBF = -0.0580635   Chr17 : 68,333,424
0.001 0.999 0.000
rs12373124 lBF = 1.68074   Chr17 : 43,924,219
0.000 0.999 0.001
rs6504108 lBF = -0.146447   Chr17 : 46,292,923
0.000 0.999 0.001
rs1981997 lBF = 1.64472   Chr17 : 44,056,767
0.000 0.999 0.001
rs1864325 lBF = 1.4805   Chr17 : 43,977,827
0.000 0.999 0.001
rs77542162 lBF = 21.6691   Chr17 : 67,081,278
0.001 0.999 0.000
rs781856 lBF = 0.00298606   Chr17 : 3,950,224
0.001 0.999 0.000
rs9303525 lBF = 0.836245   Chr17 : 44,187,257
0.000 0.999 0.001
rs34145262 lBF = 0.00058225   Chr17 : 32,880,882
0.001 0.999 0.000
rs997781 lBF = -0.12996   Chr17 : 67,117,688
0.000 0.999 0.001
rs7224438 lBF = -0.00083287   Chr17 : 58,966,538
0.001 0.999 0.000
rs17780086 lBF = -0.0610869   Chr17 : 30,343,282
0.000 0.999 0.001
rs7223966 lBF = -0.159536   Chr17 : 61,893,398
0.001 0.999 0.000
rs17649553 lBF = 1.40109   Chr17 : 43,994,648
0.000 0.999 0.001
rs79169085 lBF = 0.0226909   Chr17 : 46,297,515
0.001 0.999 0.000
rs16948200 lBF = 0.00260819   Chr17 : 47,566,312
0.001 0.999 0.000
rs333119 lBF = 0.00118689   Chr17 : 4,393,498
0.001 0.999 0.000
rs8070723 lBF = 1.48669   Chr17 : 44,081,064
0.000 0.999 0.001
rs8178393 lBF = 0.00019531   Chr17 : 56,340,451
0.001 0.999 0.000
rs12453524 lBF = 0.00002118   Chr17 : 66,575,117
0.001 0.999 0.000
rs9899375 lBF = 0   Chr17 : 7,811,615
0.001 0.999 0.001
rs140385970 lBF = 0   Chr17 : 59,560,349
0.001 0.999 0.001
rs146255527 lBF = 0   Chr17 : 56,950,568
0.001 0.999 0.001
rs111786708 lBF = 0   Chr17 : 56,289,177
0.001 0.999 0.001
rs188757965 lBF = 0   Chr17 : 41,119,569
0.001 0.999 0.001
rs186171056 lBF = 0   Chr17 : 59,606,089
0.001 0.999 0.001
rs116284889 lBF = 0   Chr17 : 56,316,722
0.001 0.999 0.001
rs61744862 lBF = 0   Chr17 : 17,068,182
0.001 0.999 0.001
rs138387343 lBF = 0   Chr17 : 57,060,633
0.001 0.999 0.001
rs142991058 lBF = 0   Chr17 : 73,046,170
0.001 0.999 0.001
rs146873050 lBF = 0   Chr17 : 56,291,326
0.001 0.999 0.001
rs150758818 lBF = 0   Chr17 : 56,324,768
0.001 0.999 0.001
rs12949468 lBF = 0   Chr17 : 60,593,816
0.001 0.999 0.001
rs141829479 lBF = 0   Chr17 : 56,305,064
0.001 0.999 0.001
rs78507937 lBF = 0   Chr17 : 6,987,841
0.001 0.999 0.001
rs188840013 lBF = 0   Chr17 : 51,992,003
0.001 0.999 0.001
rs75041531 lBF = 0   Chr17 : 38,393,151
0.001 0.999 0.001
rs7210100 lBF = 0   Chr17 : 47,436,749
0.001 0.999 0.001
rs9904045 lBF = 0   Chr17 : 64,051,726
0.001 0.999 0.001
rs116372990 lBF = 0   Chr17 : 56,310,262
0.001 0.999 0.001
rs144908958 lBF = 0   Chr17 : 31,532,414
0.001 0.999 0.001
rs113203253 lBF = 0   Chr17 : 56,348,068
0.001 0.999 0.001
rs16973424 lBF = 0   Chr17 : 66,904,001
0.001 0.999 0.001
rs116885154 lBF = 0   Chr17 : 71,784,375
0.001 0.999 0.001
rs144460277 lBF = 0   Chr17 : 9,075,744
0.001 0.999 0.001
rs140543894 lBF = 0   Chr17 : 56,289,109
0.001 0.999 0.001
rs708382 lBF = -0.208344   Chr17 : 42,442,344
0.001 0.999 0.000
rs2854207 lBF = -0.172623   Chr17 : 61,947,107
0.001 0.999 0.000
rs415430 lBF = 1.20696   Chr17 : 44,859,144
0.001 0.999 0.000
rs73989024 lBF = -0.00073575   Chr17 : 48,009,469
0.000 0.999 0.000
rs8078051 lBF = -0.00082654   Chr17 : 72,251,240
0.001 0.999 0.000
rs11867934 lBF = -0.203907   Chr17 : 16,933,404
0.000 0.999 0.001
rs8072100 lBF = 3.27774   Chr17 : 45,674,687
0.001 0.999 0.000
rs199515 lBF = 1.16496   Chr17 : 44,856,641
0.001 0.999 0.000
rs12943679 lBF = 0.114847   Chr17 : 64,027,553
0.001 0.999 0.000
rs149001306 lBF = 0.0608696   Chr17 : 68,042,202
0.000 0.999 0.001
rs882367 lBF = -0.00137722   Chr17 : 59,494,574
0.000 0.999 0.000
rs117156109 lBF = -0.0239543   Chr17 : 75,856,929
0.001 0.999 0.000
rs77542162 lBF = 21.3657   Chr17 : 67,081,278
0.001 0.999 0.000
rs149464898 lBF = -0.00169972   Chr17 : 78,947,333
0.001 0.999 0.000
rs11870935 lBF = 3.28286   Chr17 : 45,732,605
0.001 0.999 0.000
rs58630086 lBF = -0.0692941   Chr17 : 6,781,413
0.000 0.999 0.001
rs11078597 lBF = -0.00122564   Chr17 : 1,618,363
0.000 0.999 0.001
rs8081319 lBF = -0.00169733   Chr17 : 35,731,081
0.000 0.999 0.000
rs1388739 lBF = -0.0790479   Chr17 : 50,677,350
0.000 0.999 0.001
rs7209435 lBF = -0.13655   Chr17 : 61,712,964
0.001 0.999 0.000
rs3809863 lBF = 2.37256   Chr17 : 45,385,012
0.000 0.999 0.001
rs76731769 lBF = -0.0246868   Chr17 : 35,063,138
0.001 0.999 0.000
rs11655081 lBF = -0.0409314   Chr17 : 66,382,209
0.001 0.999 0.000
rs199443 lBF = 1.03169   Chr17 : 44,819,565
0.000 0.999 0.001
rs228769 lBF = 0.872572   Chr17 : 42,193,185
0.000 0.999 0.000
rs186788172 lBF = -0.0020672   Chr17 : 1,239,189
0.000 0.999 0.000
rs58842514 lBF = -0.0337815   Chr17 : 76,367,270
0.001 0.999 0.000
rs4789580 lBF = -0.129905   Chr17 : 76,311,991
0.000 0.999 0.001
rs199498 lBF = 0.0684031   Chr17 : 44,865,603
0.000 0.999 0.001
rs181387571 lBF = 0.017612   Chr17 : 16,249,665
0.000 0.999 0.001
rs12602300 lBF = -0.00784325   Chr17 : 68,661,635
0.001 0.999 0.000
rs916888 lBF = 0.253409   Chr17 : 44,863,133
0.000 0.999 0.001
rs11658329 lBF = -0.139312   Chr17 : 61,763,031
0.001 0.999 0.000
rs2306658 lBF = -0.239881   Chr17 : 35,306,312
0.001 0.999 0.000
rs8753 lBF = 1.19435   Chr17 : 7,417,640
0.001 0.999 0.000
rs147068743 lBF = -0.00891128   Chr17 : 1,363,475
0.000 0.999 0.000
rs73335365 lBF = 0.0119536   Chr17 : 6,140,995
0.000 0.999 0.001
rs72925845 lBF = -0.0426125   Chr17 : 76,439,361
0.000 0.999 0.001
rs199533 lBF = 1.07275   Chr17 : 44,828,931
0.000 0.999 0.001
rs8072843 lBF = -0.00729224   Chr17 : 54,638,948
0.000 0.999 0.000
rs9900808 lBF = -0.0553706   Chr17 : 13,062,795
0.000 0.999 0.001
rs35219335 lBF = -0.113311   Chr17 : 10,077,836
0.001 0.999 0.000
rs4791774 lBF = -0.120253   Chr17 : 8,932,119
0.000 0.999 0.001
rs11077614 lBF = -0.160769   Chr17 : 70,594,629
0.000 0.999 0.001
rs17879146 lBF = -0.00037863   Chr17 : 76,219,945
0.000 0.999 0.001
rs79392787 lBF = -0.00285142   Chr17 : 6,250,054
0.000 0.999 0.000
rs2270518 lBF = -0.0147212   Chr17 : 7,758,522
0.000 0.999 0.000
rs11867410 lBF = -0.0194914   Chr17 : 64,227,363
0.001 0.999 0.000
rs111816999 lBF = -0.0210296   Chr17 : 6,882,443
0.000 0.999 0.001
rs7211756 lBF = -0.0342636   Chr17 : 15,899,675
0.000 0.999 0.000
rs9906155 lBF = -0.0533105   Chr17 : 75,701,697
0.001 0.999 0.000
rs34111070 lBF = -0.0623859   Chr17 : 61,794,198
0.001 0.999 0.000
rs2840044 lBF = -0.144599   Chr17 : 33,892,068
0.000 0.999 0.001
rs75493593 lBF = 0.0195745   Chr17 : 6,945,087
0.000 0.999 0.000
rs75418188 lBF = 0.0192944   Chr17 : 6,945,483
0.000 0.999 0.000
rs12943829 lBF = -0.00893333   Chr17 : 70,826,404
0.000 0.999 0.000
rs142643109 lBF = -0.0186871   Chr17 : 60,387,921
0.000 0.999 0.001
rs74361281 lBF = -0.0447476   Chr17 : 14,629,706
0.000 0.999 0.000
rs17183295 lBF = -0.0785725   Chr17 : 31,078,272
0.000 0.999 0.001
rs113865542 lBF = -0.0934851   Chr17 : 77,176,256
0.000 0.999 0.001
rs73976923 lBF = 0.00276504   Chr17 : 6,282,471
0.000 0.999 0.000
rs193042029 lBF = -0.00433366   Chr17 : 4,667,984
0.000 0.999 0.000
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0.001 0.999 0.000
rs17631303 lBF = 0.812767   Chr17 : 43,516,402
0.000 0.999 0.001
rs11012 lBF = 0.807561   Chr17 : 43,513,441
0.000 0.999 0.001
rs16966833 lBF = -0.0492849   Chr17 : 30,035,727
0.000 0.999 0.000
rs11078697 lBF = -0.0362521   Chr17 : 7,469,229
0.000 0.999 0.000
rs11653545 lBF = -0.0383815   Chr17 : 7,512,074
0.000 0.999 0.000
rs117813251 lBF = -0.0389971   Chr17 : 74,197,931
0.000 0.999 0.000
rs7219669 lBF = -0.0586429   Chr17 : 68,521,861
0.001 0.999 0.000
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0.001 0.999 0.000
rs2935183 lBF = 3.56246   Chr17 : 45,607,572
0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
rs12451840 lBF = -0.0622918   Chr17 : 71,807,713
0.000 0.999 0.000
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0.000 0.999 0.000
rs2006933 lBF = -0.127634   Chr17 : 26,601,133
0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
rs117616209 lBF = -0.0374671   Chr17 : 7,142,851
0.000 0.999 0.000
rs9899728 lBF = 0.170202   Chr17 : 73,018,774
0.000 0.999 0.000
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0.000 0.999 0.000
rs9895585 lBF = 0.0116281   Chr17 : 42,064,987
0.000 0.999 0.000
rs312457 lBF = 0.0106137   Chr17 : 6,940,393
0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
rs11079160 lBF = -0.119369   Chr17 : 53,404,725
0.000 0.999 0.001
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0.001 0.999 0.000
rs3091315 lBF = 0.397105   Chr17 : 32,593,665
0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
rs9890514 lBF = 0.0658392   Chr17 : 46,738,883
0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
rs7206971 lBF = 3.40989   Chr17 : 45,425,115
0.000 1.000 0.000
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0.000 1.000 0.000
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rs2250422 lBF = -0.107642   Chr17 : 48,351,018
0.000 1.000 0.000
rs11870068 lBF = -0.111807   Chr17 : 65,944,515
0.000 1.000 0.000
rs4273077 lBF = -0.111915   Chr17 : 16,849,139
0.000 1.000 0.000
rs8077059 lBF = -0.115545   Chr17 : 55,823,552
0.000 1.000 0.000
rs72863877 lBF = -0.122753   Chr17 : 68,206,397
0.000 1.000 0.000
rs9891572 lBF = -0.124135   Chr17 : 2,428,508
0.000 1.000 0.000
rs7502947 lBF = -0.163732   Chr17 : 57,229,716
0.000 1.000 0.000
rs447921 lBF = -0.169162   Chr17 : 74,414,559
0.000 1.000 0.000
rs8074980 lBF = -0.187537   Chr17 : 56,010,960
0.000 1.000 0.000
rs12451788 lBF = -0.187944   Chr17 : 1,941,048
0.000 1.000 0.000
rs411988 lBF = -0.188643   Chr17 : 56,709,034
0.000 1.000 0.000
rs412000 lBF = -0.190489   Chr17 : 56,709,058
0.000 1.000 0.000
rs2302777 lBF = 10.8764   Chr17 : 38,179,492
0.000 1.000 0.000
rs9913911 lBF = 9.90845   Chr17 : 10,031,183
0.000 1.000 0.000
rs8081264 lBF = 9.41744   Chr17 : 7,235,316
0.000 1.000 0.000
rs169313 lBF = 1.22275   Chr17 : 10,567,483
0.000 1.000 0.000
rs2854160 lBF = 0.717141   Chr17 : 61,977,248
0.000 1.000 0.000
rs7214628 lBF = 0.665893   Chr17 : 73,882,148
0.000 1.000 0.000
rs3744028 lBF = 0.516416   Chr17 : 73,888,672
0.000 1.000 0.000
rs8066857 lBF = 0.409943   Chr17 : 70,696,103
0.000 1.000 0.000
rs12601358 lBF = 0.383472   Chr17 : 11,094,177
0.000 1.000 0.000
rs3889237 lBF = 0.0400298   Chr17 : 64,779,430
0.000 1.000 0.000
rs17881320 lBF = 0.0143817   Chr17 : 40,485,239
0.000 1.000 0.000
rs72829446 lBF = -0.0177953   Chr17 : 7,552,123
0.000 1.000 0.000
rs3826538 lBF = -0.0235075   Chr17 : 1,794,208
0.000 1.000 0.000
rs4273100 lBF = -0.0237742   Chr17 : 19,153,417
0.000 1.000 0.000
rs218676 lBF = -0.0274072   Chr17 : 6,607,018
0.000 1.000 0.000
rs11653989 lBF = -0.0336814   Chr17 : 75,004,213
0.000 1.000 0.000
rs2286672 lBF = -0.0393445   Chr17 : 4,712,617
0.000 1.000 0.000
rs4430796 lBF = -0.0425854   Chr17 : 36,098,040
0.000 1.000 0.000
rs76525880 lBF = -0.043495   Chr17 : 46,614,250
0.000 1.000 0.000
rs3785982 lBF = -0.0502726   Chr17 : 9,090,224
0.000 1.000 0.000
rs11650494 lBF = -0.0549918   Chr17 : 47,345,186
0.000 1.000 0.000
rs75023836 lBF = -0.0554392   Chr17 : 9,188,598
0.000 1.000 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.