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Diagnostic term associations

Self-Reported Statistics (SRS)

Aortic regurgitation / incompetence
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs117564322 lBF = 2.69692   Chr7 : 150,684,021
0.332 0.668 0.000
rs3918226 lBF = 12.2695   Chr7 : 150,690,176
0.214 0.786 0.001
rs11556924 lBF = 4.7389   Chr7 : 129,663,496
0.000 0.809 0.191
rs2107595 lBF = 3.80288   Chr7 : 19,049,388
0.133 0.866 0.001
rs57301765 lBF = 2.99028   Chr7 : 19,052,733
0.116 0.883 0.001
rs73066442 lBF = 7.61964   Chr7 : 21,592,973
0.079 0.921 0.000
rs17398575 lBF = 0.0504539   Chr7 : 106,409,452
0.027 0.973 0.000
rs113118439 lBF = 0.191513   Chr7 : 5,487,229
0.020 0.979 0.000
rs55649657 lBF = 9.56022   Chr7 : 21,607,283
0.018 0.982 0.000
rs77224425 lBF = 0.117562   Chr7 : 36,087,216
0.016 0.984 0.000
rs798502 lBF = 1.54652   Chr7 : 2,789,880
0.000 0.988 0.012
rs6976769 lBF = 0.103028   Chr7 : 83,297,262
0.011 0.989 0.000
rs13245899 lBF = 0.0577771   Chr7 : 100,497,131
0.011 0.989 0.000
rs56130071 lBF = 8.99314   Chr7 : 21,598,753
0.010 0.990 0.000
rs798497 lBF = 1.60686   Chr7 : 2,795,957
0.000 0.991 0.009
rs797820 lBF = -0.0891298   Chr7 : 83,609,039
0.000 0.991 0.009
rs12666989 lBF = 0.0549091   Chr7 : 100,486,754
0.009 0.991 0.000
rs7777484 lBF = 0.00808249   Chr7 : 2,814,271
0.000 0.992 0.008
rs798544 lBF = 0.76856   Chr7 : 2,763,102
0.000 0.992 0.008
rs314370 lBF = 0.106906   Chr7 : 100,453,208
0.008 0.992 0.000
rs798554 lBF = 0.876726   Chr7 : 2,759,795
0.000 0.993 0.007
rs1182188 lBF = 0.972482   Chr7 : 2,869,985
0.000 0.993 0.007
rs12670798 lBF = 7.77205   Chr7 : 21,607,352
0.006 0.994 0.000
rs1800795 lBF = 0.744038   Chr7 : 22,766,645
0.000 0.994 0.006
rs798489 lBF = 0.758014   Chr7 : 2,801,803
0.000 0.995 0.005
rs4410790 lBF = 0.261217   Chr7 : 17,284,577
0.000 0.995 0.005
rs17477177 lBF = -0.0569173   Chr7 : 106,411,858
0.005 0.995 0.000
rs6968554 lBF = 0.321945   Chr7 : 17,287,106
0.000 0.995 0.005
rs9920 lBF = 2.25442   Chr7 : 116,200,092
0.000 0.995 0.005
rs4646450 lBF = 0.0090158   Chr7 : 99,266,318
0.000 0.995 0.005
rs191603973 lBF = 0.0684295   Chr7 : 155,101,686
0.004 0.995 0.000
rs11978472 lBF = -0.103335   Chr7 : 81,839,553
0.004 0.996 0.000
rs11773845 lBF = 7.55688   Chr7 : 116,191,301
0.004 0.996 0.000
rs6465657 lBF = 0.251497   Chr7 : 97,816,327
0.004 0.996 0.000
rs146131423 lBF = 0.012458   Chr7 : 75,896,741
0.004 0.996 0.000
rs6968865 lBF = 0.305479   Chr7 : 17,287,269
0.000 0.996 0.004
rs3807989 lBF = 7.39522   Chr7 : 116,186,241
0.004 0.996 0.000
rs6465657 lBF = 0.254668   Chr7 : 97,816,327
0.000 0.996 0.004
rs75672964 lBF = 0.115217   Chr7 : 131,321,010
0.003 0.997 0.000
rs10486003 lBF = -0.0346589   Chr7 : 97,229,778
0.003 0.997 0.000
rs2074633 lBF = 0.0724459   Chr7 : 19,035,920
0.003 0.997 0.000
rs875971 lBF = -0.064761   Chr7 : 65,617,595
0.003 0.997 0.000
rs3757584 lBF = 0.887582   Chr7 : 73,440,695
0.003 0.997 0.000
rs10270308 lBF = 0.0722869   Chr7 : 105,671,267
0.003 0.997 0.000
rs12670403 lBF = -0.108911   Chr7 : 17,309,279
0.000 0.997 0.003
rs1179624 lBF = -0.217269   Chr7 : 75,255,215
0.000 0.997 0.003
rs1668357 lBF = -0.0835611   Chr7 : 38,004,406
0.000 0.997 0.003
rs13307587 lBF = -0.162184   Chr7 : 13,543,729
0.003 0.997 0.000
rs192739715 lBF = 0.129257   Chr7 : 52,165,757
0.002 0.997 0.000
rs1357978 lBF = -0.166378   Chr7 : 13,560,221
0.003 0.997 0.000
rs13227425 lBF = -0.165341   Chr7 : 13,554,008
0.002 0.998 0.000
rs929351 lBF = -0.131206   Chr7 : 81,857,893
0.000 0.998 0.002
rs1499614 lBF = -0.0637016   Chr7 : 65,730,798
0.002 0.998 0.000
rs72602052 lBF = 0.0470946   Chr7 : 28,500,531
0.002 0.998 0.000
rs2730245 lBF = -0.178241   Chr7 : 158,724,789
0.002 0.998 0.000
rs372229746 lBF = -0.0571606   Chr7 : 102,158,815
0.002 0.998 0.000
rs1635852 lBF = 1.34958   Chr7 : 28,189,411
0.000 0.998 0.002
rs2243480 lBF = -0.0657767   Chr7 : 65,599,196
0.000 0.998 0.002
rs1142 lBF = -0.00494433   Chr7 : 104,756,326
0.002 0.998 0.000
rs2286195 lBF = 0.0470075   Chr7 : 139,728,584
0.001 0.998 0.001
rs17172199 lBF = -0.0895872   Chr7 : 43,377,276
0.002 0.998 0.000
rs4718428 lBF = -0.111944   Chr7 : 66,421,446
0.000 0.998 0.002
rs73313346 lBF = -0.0168476   Chr7 : 18,723,232
0.002 0.998 0.000
rs849134 lBF = 1.6481   Chr7 : 28,196,222
0.002 0.998 0.000
rs6949729 lBF = 0.796616   Chr7 : 141,362,431
0.002 0.998 0.000
rs13236243 lBF = 0.142947   Chr7 : 17,318,312
0.000 0.998 0.002
rs6954895 lBF = -0.0365626   Chr7 : 35,586,206
0.000 0.998 0.002
rs552707 lBF = 0.054138   Chr7 : 28,205,303
0.000 0.998 0.002
rs6462018 lBF = -0.102586   Chr7 : 27,519,118
0.002 0.998 0.000
rs3807766 lBF = -0.140419   Chr7 : 77,682,890
0.002 0.998 0.000
rs849134 lBF = 1.86294   Chr7 : 28,196,222
0.000 0.998 0.002
rs864745 lBF = 2.2156   Chr7 : 28,180,556
0.000 0.998 0.002
rs849142 lBF = 1.93781   Chr7 : 28,185,891
0.000 0.998 0.002
rs75511781 lBF = 0.249713   Chr7 : 131,323,710
0.001 0.998 0.000
rs3736638 lBF = 0.040438   Chr7 : 94,047,266
0.001 0.998 0.000
rs1534696 lBF = -0.191619   Chr7 : 26,397,239
0.000 0.998 0.002
rs2299148 lBF = -0.07979   Chr7 : 42,023,400
0.002 0.998 0.000
rs4721377 lBF = -0.191544   Chr7 : 14,855,062
0.000 0.998 0.002
rs113308315 lBF = 0.0401956   Chr7 : 49,916,006
0.001 0.998 0.000
rs79091781 lBF = 0.0106729   Chr7 : 94,430,452
0.001 0.998 0.000
rs886716 lBF = -0.176298   Chr7 : 26,557,618
0.000 0.998 0.002
rs1029534 lBF = -0.0211824   Chr7 : 28,189,083
0.000 0.998 0.002
rs1708299 lBF = -0.0221532   Chr7 : 28,189,946
0.000 0.998 0.002
rs849135 lBF = 1.82882   Chr7 : 28,196,413
0.000 0.998 0.002
rs1010366 lBF = -0.134344   Chr7 : 7,229,826
0.002 0.998 0.000
rs2097677 lBF = 0.220577   Chr7 : 22,732,839
0.000 0.998 0.002
rs4725479 lBF = -0.164217   Chr7 : 152,745,810
0.002 0.998 0.000
rs849141 lBF = 0.1421   Chr7 : 28,185,091
0.000 0.998 0.002
rs7800668 lBF = -0.0420779   Chr7 : 117,459,043
0.000 0.998 0.001
rs10808265 lBF = -0.14568   Chr7 : 132,189,689
0.000 0.998 0.002
rs180242 lBF = -0.225175   Chr7 : 93,549,596
0.000 0.998 0.002
rs7781977 lBF = -0.0892303   Chr7 : 50,346,134
0.002 0.998 0.000
rs6465468 lBF = -0.105923   Chr7 : 95,169,514
0.000 0.998 0.002
rs7802124 lBF = 3.01338   Chr7 : 116,205,914
0.000 0.998 0.001
rs6943555 lBF = -0.0271251   Chr7 : 69,806,023
0.000 0.998 0.001
rs12700667 lBF = -0.176613   Chr7 : 25,901,639
0.002 0.998 0.000
rs11772815 lBF = -0.178293   Chr7 : 28,391,047
0.000 0.998 0.001
rs71564781 lBF = -0.029514   Chr7 : 106,041,964
0.001 0.998 0.000
rs7785360 lBF = -0.143765   Chr7 : 69,409,378
0.000 0.998 0.001
rs2909678 lBF = 0.0800558   Chr7 : 131,334,001
0.001 0.999 0.000
rs4294134 lBF = -0.149404   Chr7 : 135,293,128
0.001 0.999 0.000
rs7812088 lBF = -0.0591249   Chr7 : 150,919,829
0.001 0.999 0.000
rs12531540 lBF = 0.536092   Chr7 : 28,162,674
0.000 0.999 0.001
rs76720445 lBF = 0.389604   Chr7 : 1,792,396
0.001 0.999 0.000
rs1122979 lBF = -0.0507835   Chr7 : 150,915,071
0.001 0.999 0.000
rs11765845 lBF = -0.217868   Chr7 : 28,391,142
0.000 0.999 0.001
rs343064 lBF = 0.00847925   Chr7 : 35,554,788
0.001 0.999 0.000
rs17736906 lBF = -0.107597   Chr7 : 53,982,626
0.001 0.999 0.000
rs2429582 lBF = -0.175345   Chr7 : 122,202,593
0.000 0.999 0.001
rs180273 lBF = -0.190391   Chr7 : 93,538,295
0.000 0.999 0.001
rs4726279 lBF = -0.0692453   Chr7 : 153,056,620
0.000 0.999 0.001
rs17158483 lBF = -0.0870729   Chr7 : 29,962,524
0.001 0.999 0.000
rs7801303 lBF = -0.138691   Chr7 : 40,918,070
0.000 0.999 0.001
rs11977526 lBF = -0.155798   Chr7 : 46,008,110
0.001 0.999 0.000
rs38989 lBF = -0.229234   Chr7 : 153,578,416
0.001 0.999 0.000
rs7781370 lBF = 0.527702   Chr7 : 96,133,531
0.000 0.999 0.001
rs4727338 lBF = 0.383343   Chr7 : 96,120,675
0.000 0.999 0.001
rs308097 lBF = 0.0257695   Chr7 : 5,880,377
0.001 0.999 0.000
rs4731742 lBF = -0.010129   Chr7 : 130,754,812
0.001 0.999 0.000
rs2075671 lBF = -0.140665   Chr7 : 100,345,106
0.001 0.999 0.000
rs17151904 lBF = -0.165745   Chr7 : 25,608,409
0.000 0.999 0.001
rs10239506 lBF = -0.176572   Chr7 : 32,216,893
0.000 0.999 0.001
rs245914 lBF = -0.193882   Chr7 : 29,218,159
0.001 0.999 0.000
rs1859596 lBF = -0.0646987   Chr7 : 79,109,642
0.001 0.999 0.000
rs10952362 lBF = -0.0828655   Chr7 : 152,262,798
0.000 0.999 0.001
rs186166891 lBF = 6.92511   Chr7 : 40,406,876
0.001 0.999 0.000
rs4729260 lBF = 0.600487   Chr7 : 96,117,918
0.000 0.999 0.001
rs5009270 lBF = 0.152921   Chr7 : 112,159,178
0.000 0.999 0.001
rs10251504 lBF = 0.060002   Chr7 : 77,689,888
0.001 0.999 0.000
rs10488031 lBF = -0.0947953   Chr7 : 37,076,854
0.001 0.999 0.000
rs10229603 lBF = -0.17213   Chr7 : 112,628,373
0.001 0.999 0.000
rs6980334 lBF = -0.078803   Chr7 : 137,788,492
0.001 0.999 0.000
rs4727012 lBF = -0.139512   Chr7 : 148,740,493
0.001 0.999 0.000
rs62468398 lBF = -0.0562702   Chr7 : 131,893,485
0.001 0.999 0.000
rs14978 lBF = -0.0576826   Chr7 : 12,273,152
0.001 0.999 0.000
rs1000597 lBF = 0.719228   Chr7 : 30,937,178
0.001 0.999 0.000
rs9638182 lBF = 6.81008   Chr7 : 72,999,105
0.000 0.999 0.001
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0.001 0.999 0.000
rs10255329 lBF = 0.0105716   Chr7 : 13,440,222
0.001 0.999 0.000
rs17168526 lBF = 0.00588784   Chr7 : 7,571,420
0.001 0.999 0.000
rs7809615 lBF = -0.054376   Chr7 : 99,184,778
0.000 0.999 0.001
rs4730775 lBF = -0.077965   Chr7 : 116,917,118
0.000 0.999 0.001
rs7802263 lBF = -0.114815   Chr7 : 124,384,327
0.000 0.999 0.001
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0.001 0.999 0.000
rs10278040 lBF = -0.0399143   Chr7 : 99,141,373
0.000 0.999 0.001
rs11974702 lBF = -0.0399583   Chr7 : 99,163,951
0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs13247874 lBF = 6.8808   Chr7 : 73,010,442
0.000 0.999 0.001
rs10237735 lBF = -0.00103009   Chr7 : 32,376,748
0.001 0.999 0.000
rs6583437 lBF = -0.130508   Chr7 : 50,350,267
0.001 0.999 0.000
rs4917017 lBF = -0.0859326   Chr7 : 50,335,232
0.001 0.999 0.000
rs17150687 lBF = 0.00292372   Chr7 : 78,043,291
0.001 0.999 0.000
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0.001 0.999 0.000
rs12533251 lBF = -0.0631193   Chr7 : 99,115,677
0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
rs10226930 lBF = 0.00011944   Chr7 : 155,837,295
0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs4557589 lBF = -0.0777226   Chr7 : 2,924,082
0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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rs1949829 lBF = -0.0542322   Chr7 : 51,537,887
0.001 0.999 0.000
rs4723619 lBF = -0.0622285   Chr7 : 37,266,352
0.001 0.999 0.000
rs6956741 lBF = -0.0634525   Chr7 : 112,094,743
0.001 0.999 0.000
rs7798197 lBF = -0.0668021   Chr7 : 19,037,661
0.000 0.999 0.000
rs6964415 lBF = -0.0838729   Chr7 : 46,242,583
0.001 0.999 0.000
rs2969540 lBF = -0.0904342   Chr7 : 154,900,857
0.000 0.999 0.001
rs10261878 lBF = -0.120001   Chr7 : 25,950,545
0.001 0.999 0.000
rs9641855 lBF = -0.190834   Chr7 : 129,356,206
0.001 0.999 0.000
rs75290158 lBF = 0.142828   Chr7 : 96,652,459
0.000 0.999 0.000
rs10952890 lBF = 0.0688403   Chr7 : 86,355,215
0.001 0.999 0.000
rs10155981 lBF = 0.0470551   Chr7 : 22,756,463
0.000 0.999 0.001
rs1399090 lBF = 0.0362327   Chr7 : 131,829,128
0.000 0.999 0.001
rs74757156 lBF = 0.0319379   Chr7 : 136,238,782
0.001 0.999 0.000
rs73079954 lBF = 0.0314781   Chr7 : 24,746,536
0.000 0.999 0.000
rs115821935 lBF = -0.00338049   Chr7 : 90,738,831
0.001 0.999 0.000
rs500454 lBF = -0.00611272   Chr7 : 80,799,834
0.000 0.999 0.000
rs73302615 lBF = -0.0111741   Chr7 : 28,271,690
0.000 0.999 0.000
rs528161076 lBF = -0.0115897   Chr7 : 4,827,514
0.001 0.999 0.000
rs146885652 lBF = -0.0201193   Chr7 : 136,172,773
0.001 0.999 0.000
rs118189482 lBF = -0.0289305   Chr7 : 154,460,660
0.001 0.999 0.000
rs144872818 lBF = -0.0433787   Chr7 : 49,894,195
0.000 0.999 0.000
rs142857449 lBF = -0.0492114   Chr7 : 85,048,380
0.000 0.999 0.000
rs76721197 lBF = -0.0517727   Chr7 : 106,727,200
0.001 0.999 0.000
rs10263639 lBF = -0.0622452   Chr7 : 67,059,267
0.000 0.999 0.001
rs62446123 lBF = -0.11503   Chr7 : 22,113,818
0.001 0.999 0.000
rs73678284 lBF = -0.155458   Chr7 : 10,700,897
0.001 0.999 0.000
rs1722133 lBF = -0.168466   Chr7 : 46,128,109
0.001 0.999 0.000
rs12538707 lBF = 10.9268   Chr7 : 87,124,268
0.000 0.999 0.001

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.