TreeWAS – Aortic valve disease

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs6698843 lBF = `17.827` Chr`1` : `109,806,834`	0.612	0.388	0.000
rs3902354 lBF = `65.6471` Chr`1` : `109,819,296`	0.600	0.400	0.000
rs6657811 lBF = `55.0505` Chr`1` : `109,807,283`	0.000	0.419	0.581
rs17162040 lBF = `2.31284` Chr`1` : `27,883,227`	0.000	0.428	0.572
rs660240 lBF = `119.202` Chr`1` : `109,817,838`	0.538	0.462	0.000
rs191448950 lBF = `16.1321` Chr`1` : `55,584,844`	0.000	0.489	0.511
rs114113732 lBF = `6.43865` Chr`1` : `170,152,756`	0.504	0.496	0.000
rs629301 lBF = `124.149` Chr`1` : `109,818,306`	0.503	0.497	0.000
rs646776 lBF = `124.27` Chr`1` : `109,818,530`	0.503	0.497	0.000
rs629301 lBF = `124.875` Chr`1` : `109,818,306`	0.000	0.497	0.503
rs602633 lBF = `116.063` Chr`1` : `109,821,511`	0.496	0.503	0.000
rs12740374 lBF = `125.704` Chr`1` : `109,817,590`	0.000	0.508	0.492
rs599839 lBF = `116.601` Chr`1` : `109,822,166`	0.474	0.525	0.000
rs7528419 lBF = `121.876` Chr`1` : `109,817,192`	0.000	0.531	0.469
rs6679677 lBF = `158.346` Chr`1` : `114,303,808`	0.457	0.543	0.000
rs11591147 lBF = `77.3736` Chr`1` : `55,505,647`	0.000	0.559	0.441
rs11591147 lBF = `76.3456` Chr`1` : `55,505,647`	0.000	0.559	0.441
rs61819372 lBF = `8.34272` Chr`1` : `114,072,110`	0.423	0.577	0.000
rs74434895 lBF = `7.60443` Chr`1` : `113,934,072`	0.418	0.582	0.000
rs17465637 lBF = `13.0755` Chr`1` : `222,823,529`	0.000	0.615	0.385
rs35700460 lBF = `12.8646` Chr`1` : `222,811,407`	0.381	0.619	0.000
rs17465637 lBF = `13.2352` Chr`1` : `222,823,529`	0.374	0.625	0.000
rs67180937 lBF = `11.9763` Chr`1` : `222,823,743`	0.374	0.625	0.000
rs2476601 lBF = `160.809` Chr`1` : `114,377,568`	0.374	0.626	0.000
rs3002142 lBF = `3.69933` Chr`1` : `222,788,062`	0.372	0.628	0.000
rs2476601 lBF = `159.383` Chr`1` : `114,377,568`	0.000	0.664	0.336
rs61772626 lBF = `1.31081` Chr`1` : `57,015,668`	0.322	0.678	0.000
rs12725009 lBF = `1.05384` Chr`1` : `3,413,997`	0.000	0.736	0.263
rs17114046 lBF = `1.85091` Chr`1` : `56,966,350`	0.000	0.802	0.198
rs17114046 lBF = `2.04273` Chr`1` : `56,966,350`	0.000	0.805	0.195
rs9970807 lBF = `1.77212` Chr`1` : `56,965,664`	0.000	0.809	0.191
rs115083581 lBF = `0.776479` Chr`1` : `36,376,992`	0.189	0.811	0.000
rs10797377 lBF = `0.828682` Chr`1` : `2,922,744`	0.000	0.811	0.189
rs1998013 lBF = `1.44147` Chr`1` : `55,958,030`	0.000	0.824	0.176
rs6683071 lBF = `3.45404` Chr`1` : `222,923,351`	0.175	0.825	0.000
rs17111652 lBF = `4.49706` Chr`1` : `55,590,465`	0.146	0.854	0.000
rs79598313 lBF = `6.3307` Chr`1` : `27,284,913`	0.141	0.859	0.001
rs17114036 lBF = `1.00854` Chr`1` : `56,962,821`	0.000	0.915	0.085
rs6025 lBF = `137.395` Chr`1` : `169,519,049`	0.046	0.954	0.000
rs78516619 lBF = `29.5761` Chr`1` : `168,889,373`	0.037	0.962	0.000
rs6025 lBF = `138.002` Chr`1` : `169,519,049`	0.000	0.969	0.031
rs76264265 lBF = `0.203023` Chr`1` : `37,309,390`	0.028	0.972	0.000
rs7512552 lBF = `0.756592` Chr`1` : `150,265,704`	0.025	0.975	0.000
rs61248406 lBF = `0.146611` Chr`1` : `60,579,337`	0.019	0.981	0.000
rs12074980 lBF = `0.28319` Chr`1` : `184,636,516`	0.014	0.985	0.000
rs16830359 lBF = `0.312238` Chr`1` : `43,596,384`	0.014	0.986	0.000
rs801112 lBF = `0.1326` Chr`1` : `228,996,622`	0.013	0.987	0.000
rs72704010 lBF = `0.074054` Chr`1` : `169,383,980`	0.011	0.988	0.000
rs1230666 lBF = `99.2507` Chr`1` : `114,173,410`	0.000	0.990	0.010
rs576523 lBF = `0.121195` Chr`1` : `160,746,076`	0.000	0.990	0.010
rs951366 lBF = `0.123014` Chr`1` : `205,685,352`	0.009	0.991	0.000
rs12742376 lBF = `2.77494` Chr`1` : `27,285,195`	0.003	0.992	0.004
rs7542900 lBF = `-0.101053` Chr`1` : `95,070,041`	0.007	0.993	0.000
rs16861990 lBF = `58.7975` Chr`1` : `169,135,127`	0.007	0.993	0.000
rs10493773 lBF = `-0.0542294` Chr`1` : `86,125,753`	0.007	0.993	0.000
rs76869799 lBF = `0.00554437` Chr`1` : `97,834,525`	0.007	0.993	0.000
rs181704351 lBF = `0.0375677` Chr`1` : `70,147,866`	0.007	0.993	0.000
rs9436116 lBF = `-0.0266099` Chr`1` : `150,454,724`	0.000	0.993	0.007
rs12748152 lBF = `2.93931` Chr`1` : `27,138,393`	0.003	0.993	0.004
rs61818925 lBF = `-0.0433617` Chr`1` : `196,815,450`	0.000	0.994	0.006
rs2820037 lBF = `0.122097` Chr`1` : `239,436,542`	0.000	0.994	0.006
rs72677908 lBF = `0.214509` Chr`1` : `62,462,325`	0.005	0.994	0.000
rs2764894 lBF = `0.220356` Chr`1` : `59,342,665`	0.000	0.995	0.005
rs3903239 lBF = `3.66517` Chr`1` : `170,569,317`	0.004	0.996	0.000
rs186478 lBF = `0.0231836` Chr`1` : `49,177,150`	0.004	0.996	0.000
rs115759551 lBF = `0.0106065` Chr`1` : `156,963,356`	0.004	0.996	0.000
rs7543130 lBF = `-0.162963` Chr`1` : `100,049,785`	0.000	0.996	0.004
rs17129289 lBF = `0.0302201` Chr`1` : `84,232,748`	0.003	0.997	0.000
rs12141041 lBF = `-0.180375` Chr`1` : `119,952,776`	0.003	0.997	0.000
rs10917477 lBF = `4.49293` Chr`1` : `19,861,106`	0.000	0.997	0.003
rs7543130 lBF = `-0.165165` Chr`1` : `100,049,785`	0.003	0.997	0.000
rs514230 lBF = `4.97436` Chr`1` : `234,858,597`	0.000	0.997	0.003
rs10157197 lBF = `-0.114205` Chr`1` : `150,250,636`	0.003	0.997	0.000
rs7551641 lBF = `0.0149307` Chr`1` : `120,017,927`	0.002	0.997	0.000
rs4521954 lBF = `-0.112166` Chr`1` : `187,681,623`	0.000	0.997	0.003
rs16937 lBF = `-0.142304` Chr`1` : `205,035,455`	0.003	0.997	0.000
rs1831282 lBF = `1.25462` Chr`1` : `196,673,993`	0.003	0.997	0.000
rs380390 lBF = `1.05449` Chr`1` : `196,701,051`	0.002	0.997	0.000
rs7547921 lBF = `-0.104835` Chr`1` : `38,602,073`	0.000	0.998	0.002
rs75080821 lBF = `0.0171806` Chr`1` : `112,264,671`	0.002	0.998	0.000
rs76597070 lBF = `0.0767197` Chr`1` : `3,669,356`	0.002	0.998	0.001
rs557933 lBF = `4.79845` Chr`1` : `234,853,268`	0.000	0.998	0.002
rs17396340 lBF = `0.292044` Chr`1` : `10,286,176`	0.002	0.998	0.000
rs1842579 lBF = `-0.0800975` Chr`1` : `86,289,082`	0.002	0.998	0.000
rs7525649 lBF = `5.43898` Chr`1` : `55,499,156`	0.002	0.998	0.001
rs1704198 lBF = `0.0380655` Chr`1` : `213,910,494`	0.000	0.998	0.002
rs661955 lBF = `4.30509` Chr`1` : `234,842,856`	0.000	0.998	0.002
rs213032 lBF = `-0.163475` Chr`1` : `21,654,735`	0.000	0.998	0.002
rs35921408 lBF = `0.0154959` Chr`1` : `184,029,795`	0.002	0.998	0.000
rs4660116 lBF = `-0.115967` Chr`1` : `236,028,841`	0.002	0.998	0.000
rs494453 lBF = `-0.131605` Chr`1` : `112,192,122`	0.000	0.998	0.002
rs823114 lBF = `0.150956` Chr`1` : `205,719,532`	0.000	0.998	0.002
rs116611433 lBF = `-0.0101771` Chr`1` : `234,277,494`	0.002	0.998	0.000
rs2068666 lBF = `0.0909114` Chr`1` : `204,917,580`	0.002	0.998	0.000
rs1884139 lBF = `-0.0902738` Chr`1` : `85,845,998`	0.000	0.998	0.002
rs823118 lBF = `0.13717` Chr`1` : `205,723,572`	0.000	0.998	0.002
rs9782955 lBF = `-0.119807` Chr`1` : `236,039,877`	0.002	0.998	0.000
rs823094 lBF = `0.0814322` Chr`1` : `205,689,807`	0.000	0.998	0.002
rs679992 lBF = `-0.113965` Chr`1` : `241,188,282`	0.002	0.998	0.000
rs9660992 lBF = `-0.108815` Chr`1` : `205,249,450`	0.002	0.998	0.000
rs4074961 lBF = `-0.162304` Chr`1` : `38,092,723`	0.000	0.998	0.002
rs548726 lBF = `-0.213537` Chr`1` : `5,913,621`	0.000	0.998	0.002
rs12138061 lBF = `0.234038` Chr`1` : `50,572,096`	0.002	0.998	0.000
rs1298637 lBF = `-0.136516` Chr`1` : `53,958,603`	0.002	0.998	0.000
rs78471656 lBF = `0.0250593` Chr`1` : `77,014,674`	0.001	0.998	0.000
rs7552806 lBF = `0.0186826` Chr`1` : `204,784,018`	0.001	0.998	0.000
rs905938 lBF = `0.937726` Chr`1` : `154,991,389`	0.001	0.998	0.000
rs425277 lBF = `0.192524` Chr`1` : `2,069,172`	0.000	0.998	0.002
rs181870845 lBF = `0.00528803` Chr`1` : `78,532,565`	0.001	0.998	0.000
rs1218582 lBF = `5.80848` Chr`1` : `154,834,183`	0.002	0.998	0.000
rs7412746 lBF = `0.250576` Chr`1` : `150,860,471`	0.001	0.998	0.000
rs12408989 lBF = `-0.0593436` Chr`1` : `209,007,778`	0.000	0.998	0.002
rs2798334 lBF = `3.79314` Chr`1` : `112,437,344`	0.000	0.998	0.001
rs138157192 lBF = `0.00821674` Chr`1` : `192,043,457`	0.001	0.998	0.000
rs12127679 lBF = `-0.0774602` Chr`1` : `244,167,801`	0.001	0.998	0.000
rs905938 lBF = `1.00876` Chr`1` : `154,991,389`	0.001	0.998	0.000
rs115699453 lBF = `0.0893218` Chr`1` : `156,827,703`	0.001	0.998	0.000
rs1775154 lBF = `-0.0336264` Chr`1` : `205,696,615`	0.000	0.998	0.001
rs12406463 lBF = `-0.0645912` Chr`1` : `209,002,220`	0.000	0.998	0.001
rs1668873 lBF = `-0.126088` Chr`1` : `205,235,990`	0.001	0.999	0.000
rs60541895 lBF = `0.0449928` Chr`1` : `42,088,393`	0.001	0.999	0.000
rs7516789 lBF = `-0.0396368` Chr`1` : `67,945,956`	0.001	0.999	0.000
rs12069356 lBF = `3.20857` Chr`1` : `154,849,771`	0.000	0.999	0.001
rs12401738 lBF = `0.301319` Chr`1` : `78,446,761`	0.000	0.999	0.001
rs10923574 lBF = `-0.112041` Chr`1` : `119,030,698`	0.000	0.999	0.001
rs631288 lBF = `0.343896` Chr`1` : `146,979,516`	0.000	0.999	0.001
rs17672135 lBF = `-0.139212` Chr`1` : `240,445,596`	0.001	0.999	0.000
rs17381664 lBF = `-0.104312` Chr`1` : `78,048,331`	0.000	0.999	0.001
rs6683419 lBF = `3.18331` Chr`1` : `19,827,780`	0.001	0.999	0.000
rs4657178 lBF = `-0.0627263` Chr`1` : `162,210,610`	0.000	0.999	0.001
rs564309 lBF = `-0.0672991` Chr`1` : `228,585,562`	0.000	0.999	0.001
rs594206 lBF = `-0.188686` Chr`1` : `147,020,456`	0.001	0.999	0.000
rs72745400 lBF = `-0.0162308` Chr`1` : `217,672,512`	0.001	0.999	0.000
rs35512961 lBF = `-0.0546865` Chr`1` : `65,151,699`	0.001	0.999	0.000
rs34130928 lBF = `-0.0730305` Chr`1` : `245,494,152`	0.001	0.999	0.000
rs11206510 lBF = `19.0749` Chr`1` : `55,496,039`	0.000	0.999	0.001
rs13376333 lBF = `12.8796` Chr`1` : `154,814,353`	0.001	0.999	0.000
rs1688589 lBF = `-0.00270727` Chr`1` : `102,029,842`	0.001	0.999	0.000
rs10443196 lBF = `-0.162475` Chr`1` : `99,453,287`	0.001	0.999	0.000
rs2820292 lBF = `-0.206161` Chr`1` : `201,784,287`	0.001	0.999	0.000
rs11204538 lBF = `-0.241739` Chr`1` : `248,046,272`	0.000	0.999	0.001
rs1018827 lBF = `63.2227` Chr`1` : `169,514,006`	0.000	0.999	0.001
rs17036023 lBF = `0.00239628` Chr`1` : `117,129,711`	0.001	0.999	0.000
rs12754946 lBF = `-0.0510607` Chr`1` : `77,989,923`	0.000	0.999	0.001
rs6666258 lBF = `12.6402` Chr`1` : `154,814,268`	0.001	0.999	0.000
rs72657827 lBF = `-0.027264` Chr`1` : `23,392,108`	0.001	0.999	0.000
rs424950 lBF = `-0.155225` Chr`1` : `163,956,503`	0.000	0.999	0.001
rs10803016 lBF = `-0.158729` Chr`1` : `242,274,908`	0.000	0.999	0.001
rs9430161 lBF = `-0.183854` Chr`1` : `11,046,855`	0.000	0.999	0.001
rs34938134 lBF = `-0.077926` Chr`1` : `245,492,965`	0.001	0.999	0.000
rs191506206 lBF = `0.00747635` Chr`1` : `191,990,367`	0.001	0.999	0.000
rs12566888 lBF = `-0.0168296` Chr`1` : `156,869,047`	0.000	0.999	0.001
rs1172130 lBF = `-0.10827` Chr`1` : `205,244,953`	0.001	0.999	0.000
rs912988 lBF = `-0.169306` Chr`1` : `5,354,844`	0.001	0.999	0.000
rs4915559 lBF = `0.0106246` Chr`1` : `196,886,770`	0.001	0.999	0.000
rs1501550 lBF = `-0.0234993` Chr`1` : `211,168,759`	0.001	0.999	0.000
rs79673927 lBF = `-0.166343` Chr`1` : `170,899,068`	0.001	0.999	0.000
rs11247594 lBF = `-0.178517` Chr`1` : `27,067,417`	0.000	0.999	0.001
rs191281603 lBF = `0.00246274` Chr`1` : `196,958,651`	0.000	0.999	0.001
rs10495471 lBF = `-0.147787` Chr`1` : `240,706,107`	0.001	0.999	0.000
rs12058524 lBF = `0.00091785` Chr`1` : `150,066,384`	0.001	0.999	0.000
rs116211639 lBF = `-0.0295988` Chr`1` : `33,400,355`	0.001	0.999	0.000
rs12085650 lBF = `-0.143905` Chr`1` : `31,490,096`	0.001	0.999	0.000
rs2724384 lBF = `-0.145671` Chr`1` : `207,930,203`	0.000	0.999	0.001
rs10881542 lBF = `-0.208148` Chr`1` : `104,852,738`	0.000	0.999	0.001
rs3014707 lBF = `0.00357925` Chr`1` : `26,009,459`	0.000	0.999	0.001
rs76620758 lBF = `0.00150262` Chr`1` : `97,375,844`	0.001	0.999	0.000
rs2268667 lBF = `-0.128685` Chr`1` : `85,793,746`	0.000	0.999	0.001
rs4656682 lBF = `18.448` Chr`1` : `169,463,518`	0.001	0.999	0.000
rs667153 lBF = `-0.0539905` Chr`1` : `30,925,952`	0.000	0.999	0.001
rs3001167 lBF = `0.0639895` Chr`1` : `194,530,914`	0.000	0.999	0.001
rs1101999 lBF = `0.00134967` Chr`1` : `158,932,555`	0.001	0.999	0.000
rs4601530 lBF = `-0.0366872` Chr`1` : `25,044,111`	0.000	0.999	0.001
rs1668871 lBF = `-0.111539` Chr`1` : `205,237,137`	0.001	0.999	0.000
rs233100 lBF = `-0.0119404` Chr`1` : `85,772,009`	0.000	0.999	0.001
rs12045693 lBF = `-0.200966` Chr`1` : `2,205,581`	0.000	0.999	0.001
rs480745 lBF = `0.00284645` Chr`1` : `83,269,970`	0.001	0.999	0.000
rs141175086 lBF = `0.00263918` Chr`1` : `780,397`	0.001	0.999	0.001
rs2390582 lBF = `-0.123659` Chr`1` : `90,943,907`	0.001	0.999	0.000
rs12143842 lBF = `-0.166534` Chr`1` : `162,033,890`	0.000	0.999	0.001
rs1293970 lBF = `-0.173574` Chr`1` : `186,258,229`	0.000	0.999	0.001
rs41314643 lBF = `0.109102` Chr`1` : `183,255,908`	0.001	0.999	0.000
rs140743827 lBF = `0.00238417` Chr`1` : `164,985,756`	0.001	0.999	0.000
rs181502228 lBF = `0.0009383` Chr`1` : `205,509,298`	0.000	0.999	0.001
rs79746559 lBF = `-0.0421523` Chr`1` : `99,463,210`	0.001	0.999	0.000
rs74546197 lBF = `-0.0610265` Chr`1` : `205,880,179`	0.000	0.999	0.001
rs6670655 lBF = `-0.128159` Chr`1` : `164,739,171`	0.001	0.999	0.000
rs1320976 lBF = `16.1152` Chr`1` : `169,073,346`	0.001	0.999	0.000
rs2297909 lBF = `1.4775` Chr`1` : `200,960,307`	0.000	0.999	0.001
rs3753573 lBF = `0.0149941` Chr`1` : `185,014,002`	0.001	0.999	0.001
rs12067906 lBF = `0.00974118` Chr`1` : `192,431,998`	0.001	0.999	0.000
rs6677208 lBF = `0.00293455` Chr`1` : `239,601,969`	0.001	0.999	0.000
rs16862426 lBF = `0.00121813` Chr`1` : `19,321,495`	0.001	0.999	0.000
rs138833465 lBF = `0.00094983` Chr`1` : `220,584,872`	0.001	0.999	0.000
rs16849553 lBF = `0.00053492` Chr`1` : `229,336,846`	0.001	0.999	0.000
rs4430311 lBF = `-0.0848449` Chr`1` : `244,015,993`	0.001	0.999	0.000
rs2651899 lBF = `10.0309` Chr`1` : `3,083,712`	0.001	0.999	0.000
rs301799 lBF = `6.93629` Chr`1` : `8,489,302`	0.000	0.999	0.001
rs79079833 lBF = `0.00273363` Chr`1` : `114,607,364`	0.001	0.999	0.000
rs12239436 lBF = `0.00218319` Chr`1` : `55,742,837`	0.001	0.999	0.001
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rs7547997 lBF = `-0.136604` Chr`1` : `158,341,273`	0.000	0.999	0.001
rs11807834 lBF = `-0.160613` Chr`1` : `230,272,624`	0.000	0.999	0.001
rs1948368 lBF = `-0.207447` Chr`1` : `101,938,477`	0.000	0.999	0.001
rs1414660 lBF = `2.37588` Chr`1` : `240,586,695`	0.000	0.999	0.001
rs12136606 lBF = `0.0728743` Chr`1` : `15,741,403`	0.001	0.999	0.000
rs4915863 lBF = `-0.00987002` Chr`1` : `63,474,881`	0.000	0.999	0.000
rs1340425 lBF = `-0.0793857` Chr`1` : `74,385,848`	0.001	0.999	0.000
rs7528276 lBF = `-0.0808539` Chr`1` : `39,809,987`	0.000	0.999	0.001
rs476463 lBF = `-0.0827938` Chr`1` : `34,248,064`	0.000	0.999	0.000
rs6691722 lBF = `-0.1192` Chr`1` : `24,673,866`	0.001	0.999	0.000
rs570618 lBF = `0.991371` Chr`1` : `196,657,064`	0.001	0.999	0.000
rs56039743 lBF = `0.735611` Chr`1` : `26,620,806`	0.000	0.999	0.000
rs114425738 lBF = `0.546202` Chr`1` : `92,171,673`	0.001	0.999	0.000
rs12144335 lBF = `0.110624` Chr`1` : `72,828,183`	0.001	0.999	0.000
rs77271258 lBF = `0.0751991` Chr`1` : `218,056,637`	0.000	0.999	0.000
rs343604 lBF = `0.0127183` Chr`1` : `111,258,770`	0.000	0.999	0.001
rs14271 lBF = `-0.00119822` Chr`1` : `9,789,150`	0.000	0.999	0.000
rs149291579 lBF = `-0.0267319` Chr`1` : `79,240,882`	0.000	0.999	0.001
rs2489260 lBF = `-0.037913` Chr`1` : `12,741,240`	0.000	0.999	0.001
rs11591201 lBF = `-0.0533755` Chr`1` : `80,301,888`	0.001	0.999	0.000
rs2651244 lBF = `-0.0631225` Chr`1` : `70,995,562`	0.001	0.999	0.000
rs10923931 lBF = `-0.0880246` Chr`1` : `120,517,959`	0.001	0.999	0.000
rs10923931 lBF = `-0.0884968` Chr`1` : `120,517,959`	0.001	0.999	0.000
rs1925714 lBF = `-0.118466` Chr`1` : `228,703,289`	0.001	0.999	0.000
rs1967689 lBF = `-0.136953` Chr`1` : `208,039,471`	0.001	0.999	0.000
rs624988 lBF = `-0.155815` Chr`1` : `117,263,790`	0.000	0.999	0.001
rs7551732 lBF = `-0.204055` Chr`1` : `89,139,041`	0.000	0.999	0.001
rs2391388 lBF = `-0.22324` Chr`1` : `95,485,825`	0.000	0.999	0.001
rs1342038 lBF = `-0.243092` Chr`1` : `173,301,516`	0.001	0.999	0.000
rs1415259 lBF = `-0.245824` Chr`1` : `162,085,309`	0.001	0.999	0.000
rs1329424 lBF = `0.926373` Chr`1` : `196,646,176`	0.001	0.999	0.000
rs12074934 lBF = `-0.0075368` Chr`1` : `159,308,071`	0.000	0.999	0.000
rs11118346 lBF = `-0.0929931` Chr`1` : `219,743,719`	0.000	0.999	0.001
rs17042140 lBF = `-0.131099` Chr`1` : `214,674,925`	0.001	0.999	0.000
rs10489615 lBF = `-0.145018` Chr`1` : `230,304,988`	0.001	0.999	0.000
rs10864728 lBF = `-0.145586` Chr`1` : `230,304,914`	0.001	0.999	0.000
rs7541937 lBF = `-0.176922` Chr`1` : `35,341,982`	0.000	0.999	0.000
rs76712070 lBF = `7.71457` Chr`1` : `243,050,615`	0.001	0.999	0.000
rs4908760 lBF = `3.69803` Chr`1` : `8,526,142`	0.000	0.999	0.001
rs10801555 lBF = `1.057` Chr`1` : `196,660,261`	0.001	0.999	0.000
rs1061170 lBF = `1.05543` Chr`1` : `196,659,237`	0.001	0.999	0.000
rs1061147 lBF = `1.05317` Chr`1` : `196,654,324`	0.001	0.999	0.000
rs4149909 lBF = `0.204898` Chr`1` : `242,023,898`	0.001	0.999	0.000
rs114080907 lBF = `0.0282004` Chr`1` : `21,077,245`	0.001	0.999	0.000
rs11240285 lBF = `-0.00686786` Chr`1` : `204,767,305`	0.000	0.999	0.000
rs2814778 lBF = `-0.00957667` Chr`1` : `159,174,683`	0.000	0.999	0.000
rs10917468 lBF = `-0.0116335` Chr`1` : `19,843,354`	0.001	0.999	0.000
rs1541252 lBF = `-0.0699563` Chr`1` : `203,651,927`	0.000	0.999	0.001
rs10900585 lBF = `-0.0706898` Chr`1` : `203,654,024`	0.000	0.999	0.001
rs6429703 lBF = `-0.128827` Chr`1` : `15,339,960`	0.001	0.999	0.000
rs12039431 lBF = `-0.140894` Chr`1` : `38,082,122`	0.001	0.999	0.000
rs212524 lBF = `-0.179824` Chr`1` : `21,583,311`	0.001	0.999	0.000
rs11121667 lBF = `-0.205724` Chr`1` : `11,038,476`	0.000	0.999	0.001
rs9287237 lBF = `2.86101` Chr`1` : `240,597,214`	0.000	0.999	0.001
rs4650135 lBF = `0.71971` Chr`1` : `69,684,997`	0.000	0.999	0.001
rs12737863 lBF = `0.023653` Chr`1` : `226,232,438`	0.001	0.999	0.000
rs11121451 lBF = `-0.00230159` Chr`1` : `9,673,843`	0.000	0.999	0.000
rs11121452 lBF = `-0.0036883` Chr`1` : `9,674,172`	0.000	0.999	0.000
rs149819415 lBF = `-0.00936021` Chr`1` : `193,639,627`	0.000	0.999	0.000
rs114162361 lBF = `-0.0135505` Chr`1` : `174,575,642`	0.000	0.999	0.000
rs7534485 lBF = `-0.0268258` Chr`1` : `168,720,621`	0.000	0.999	0.001
rs3011925 lBF = `-0.0413157` Chr`1` : `7,721,360`	0.000	0.999	0.000
rs10495332 lBF = `-0.0555462` Chr`1` : `232,756,026`	0.001	0.999	0.000
rs873917 lBF = `-0.0949376` Chr`1` : `40,132,795`	0.000	0.999	0.001
rs28588043 lBF = `-0.0970852` Chr`1` : `170,966,012`	0.001	0.999	0.000
rs13303128 lBF = `-0.106031` Chr`1` : `203,492,720`	0.001	0.999	0.000
rs10927094 lBF = `-0.114042` Chr`1` : `244,138,990`	0.000	0.999	0.001
rs590820 lBF = `-0.128027` Chr`1` : `230,309,619`	0.000	0.999	0.001
rs466639 lBF = `-0.132492` Chr`1` : `165,394,882`	0.000	0.999	0.001
rs10922162 lBF = `-0.145407` Chr`1` : `197,070,776`	0.001	0.999	0.000
rs4382726 lBF = `-0.177285` Chr`1` : `209,334,217`	0.001	0.999	0.000
rs1330225 lBF = `-0.17863` Chr`1` : `106,835,943`	0.000	0.999	0.001
rs10493485 lBF = `-0.178727` Chr`1` : `72,071,129`	0.000	0.999	0.001
rs2242194 lBF = `2.52941` Chr`1` : `154,990,297`	0.000	0.999	0.000
rs2798631 lBF = `0.0117731` Chr`1` : `218,611,878`	0.001	0.999	0.000
rs74843345 lBF = `-0.00025479` Chr`1` : `168,214,005`	0.001	0.999	0.000
rs115263666 lBF = `-0.00177087` Chr`1` : `195,978,714`	0.001	0.999	0.000
rs74823926 lBF = `-0.0143298` Chr`1` : `88,729,683`	0.000	0.999	0.000
rs17375901 lBF = `-0.0235601` Chr`1` : `11,852,516`	0.001	0.999	0.000
rs1149336 lBF = `-0.0793139` Chr`1` : `7,532,290`	0.001	0.999	0.000
rs12142669 lBF = `-0.130759` Chr`1` : `188,383,316`	0.000	0.999	0.001
rs6586513 lBF = `-0.145017` Chr`1` : `17,216,331`	0.000	0.999	0.001
rs10127775 lBF = `-0.153519` Chr`1` : `230,295,789`	0.001	0.999	0.000
rs6693388 lBF = `-0.169943` Chr`1` : `151,930,645`	0.001	0.999	0.000
rs285480 lBF = `-0.189014` Chr`1` : `165,403,903`	0.000	0.999	0.001
rs701157 lBF = `-0.255624` Chr`1` : `230,674,826`	0.000	0.999	0.001
rs4908799 lBF = `0.0229149` Chr`1` : `9,031,053`	0.000	0.999	0.000
rs150968551 lBF = `0.0111261` Chr`1` : `47,428,558`	0.000	0.999	0.000
rs114190122 lBF = `-0.00698663` Chr`1` : `9,879,349`	0.000	0.999	0.000
rs73004856 lBF = `-0.00739568` Chr`1` : `152,487,917`	0.000	0.999	0.000
rs72753808 lBF = `-0.00750237` Chr`1` : `204,517,487`	0.000	0.999	0.000
rs2445130 lBF = `-0.00802947` Chr`1` : `22,237,722`	0.000	0.999	0.000
rs115555031 lBF = `-0.0179193` Chr`1` : `240,726,984`	0.000	0.999	0.000
rs2121477 lBF = `-0.0262111` Chr`1` : `159,568,260`	0.001	0.999	0.000
rs17025426 lBF = `-0.045915` Chr`1` : `110,645,327`	0.001	0.999	0.000
rs11590526 lBF = `-0.05561` Chr`1` : `116,427,567`	0.001	0.999	0.000
rs10910623 lBF = `-0.0679416` Chr`1` : `232,938,699`	0.000	0.999	0.000
rs12042052 lBF = `-0.0685016` Chr`1` : `232,935,719`	0.000	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Heart valve problem/heart murmur
Nested terms	Aortic stenosis Aortic regurgitation / incompetence

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)