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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Self-Reported Statistics (SRS)

Psychological/psychiatric problem
Parent term
Neurology/eye/psychiatry
Nested terms
Anxiety/panic attacks
Nervous breakdown
Schizophrenia
Deliberate self-harm/suicide attempt
Mania/bipolar disorder/manic depression
Post-traumatic stress disorder
Anorexia/bulimia/other eating disorder
Stress
Obsessive compulsive disorder (ocd)
Insomnia
Substance abuse/dependency
Depression
What are diagnostic terms?
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs2851391 lBF = 0.123048   Chr21 : 44,487,404
0.070 0.930 0.000
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0.007 0.993 0.000
rs4293630 lBF = -0.103223   Chr21 : 47,445,791
0.000 0.998 0.002
rs7275460 lBF = 0.0209948   Chr21 : 41,447,058
0.000 0.998 0.002
rs933117 lBF = 0.0033177   Chr21 : 31,100,797
0.000 0.998 0.002
rs8134605 lBF = -0.0164352   Chr21 : 32,304,266
0.001 0.999 0.000
rs147130662 lBF = 0.00329226   Chr21 : 28,830,255
0.001 0.999 0.000
rs16993221 lBF = 0.005562   Chr21 : 36,849,419
0.001 0.999 0.000
rs4148087 lBF = -0.131677   Chr21 : 43,622,267
0.000 0.999 0.001
rs9984110 lBF = -0.0375093   Chr21 : 31,447,366
0.001 0.999 0.000
rs16992204 lBF = 0.00040904   Chr21 : 36,111,201
0.001 0.999 0.000
rs4148112 lBF = 0.00060422   Chr21 : 43,650,776
0.001 0.999 0.000
rs142976294 lBF = 0   Chr21 : 28,927,121
0.001 0.999 0.001
rs142429672 lBF = 0   Chr21 : 28,885,691
0.001 0.999 0.001
rs186825689 lBF = 0   Chr21 : 48,006,053
0.001 0.999 0.001
rs141838403 lBF = 0   Chr21 : 28,890,426
0.001 0.999 0.001
rs139916902 lBF = 0   Chr21 : 28,842,080
0.001 0.999 0.001
rs139202427 lBF = 0   Chr21 : 28,917,934
0.001 0.999 0.001
rs75030518 lBF = 0   Chr21 : 36,313,784
0.001 0.999 0.001
rs142181472 lBF = 0   Chr21 : 28,860,237
0.001 0.999 0.001
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0.000 0.999 0.000
rs78211511 lBF = -0.00080145   Chr21 : 17,562,284
0.001 0.999 0.000
rs2298450 lBF = 0.244883   Chr21 : 37,623,447
0.000 0.999 0.001
rs7283054 lBF = -0.00751028   Chr21 : 31,519,307
0.001 0.999 0.000
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0.001 0.999 0.000
rs145672791 lBF = 0.0489402   Chr21 : 14,750,023
0.001 0.999 0.000
rs118136136 lBF = 0.0109984   Chr21 : 35,274,965
0.001 0.999 0.000
rs16994935 lBF = 0.0508092   Chr21 : 38,671,418
0.000 0.999 0.001
rs2833197 lBF = -0.00040329   Chr21 : 32,407,116
0.000 0.999 0.000
rs16994508 lBF = -0.0298406   Chr21 : 38,189,679
0.001 0.999 0.000
rs111892515 lBF = 0.0264569   Chr21 : 23,392,906
0.000 0.999 0.001
rs727957 lBF = -0.101258   Chr21 : 35,880,072
0.000 0.999 0.001
rs112308695 lBF = 0.0113937   Chr21 : 18,297,682
0.000 0.999 0.000
rs451390 lBF = 0.00311486   Chr21 : 43,343,510
0.000 1.000 0.000
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0.000 1.000 0.000
rs116990435 lBF = -0.0233621   Chr21 : 42,048,274
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
rs74203920 lBF = 0.0027776   Chr21 : 45,714,294
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
rs17272021 lBF = -0.0596   Chr21 : 47,491,937
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
rs9979250 lBF = -0.0881101   Chr21 : 40,283,733
0.000 1.000 0.000
rs28451064 lBF = 13.6316   Chr21 : 35,593,827
0.000 1.000 0.000
rs11088872 lBF = 0.0731969   Chr21 : 23,033,104
0.000 1.000 0.000
rs614092 lBF = 0.0290949   Chr21 : 29,182,773
0.000 1.000 0.000
rs28456019 lBF = -0.0166263   Chr21 : 32,401,130
0.000 1.000 0.000
rs1899875 lBF = -0.0454446   Chr21 : 22,669,522
0.000 1.000 0.000
rs9305406 lBF = -0.129987   Chr21 : 31,386,243
0.000 1.000 0.000
rs17229494 lBF = -0.13271   Chr21 : 38,928,100
0.000 1.000 0.000
rs113512172 lBF = -0.00206144   Chr21 : 32,718,685
0.000 1.000 0.000
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0.000 1.000 0.000
rs117589273 lBF = -0.0585441   Chr21 : 46,992,250
0.000 1.000 0.000
rs7279441 lBF = -0.0746555   Chr21 : 24,198,815
0.000 1.000 0.000
rs1297265 lBF = 3.10336   Chr21 : 16,817,051
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
rs1736020 lBF = 3.54544   Chr21 : 16,812,552
0.000 1.000 0.000
rs2014791 lBF = 0.76827   Chr21 : 23,145,950
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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rs11700808 lBF = -0.0960359   Chr21 : 20,238,855
0.000 1.000 0.000
rs9976767 lBF = -0.0966141   Chr21 : 43,836,390
0.000 1.000 0.000
rs1006899 lBF = -0.103135   Chr21 : 15,845,052
0.000 1.000 0.000
rs9977499 lBF = -0.104085   Chr21 : 28,734,997
0.000 1.000 0.000
rs2839627 lBF = -0.104977   Chr21 : 44,448,718
0.000 1.000 0.000
rs55706246 lBF = -0.105106   Chr21 : 35,595,637
0.000 1.000 0.000
rs441810 lBF = -0.106555   Chr21 : 42,698,907
0.000 1.000 0.000
rs11088226 lBF = -0.106662   Chr21 : 33,925,531
0.000 1.000 0.000
rs7283316 lBF = -0.106874   Chr21 : 32,216,253
0.000 1.000 0.000
rs457352 lBF = -0.108723   Chr21 : 31,244,478
0.000 1.000 0.000
rs1452093 lBF = -0.109854   Chr21 : 28,744,356
0.000 1.000 0.000
rs2836326 lBF = -0.110278   Chr21 : 39,721,764
0.000 1.000 0.000
rs9975851 lBF = -0.112266   Chr21 : 27,716,654
0.000 1.000 0.000
rs9980664 lBF = -0.113267   Chr21 : 34,734,510
0.000 1.000 0.000
rs2205299 lBF = -0.113924   Chr21 : 18,206,630
0.000 1.000 0.000
rs743446 lBF = -0.114485   Chr21 : 40,056,423
0.000 1.000 0.000
rs1013063 lBF = -0.117384   Chr21 : 35,698,390
0.000 1.000 0.000
rs9977253 lBF = -0.118195   Chr21 : 26,645,083
0.000 1.000 0.000
rs13048019 lBF = -0.119703   Chr21 : 32,918,294
0.000 1.000 0.000
rs4819143 lBF = -0.121886   Chr21 : 47,124,178
0.000 1.000 0.000
rs2837960 lBF = -0.125545   Chr21 : 42,511,918
0.000 1.000 0.000
rs2833522 lBF = -0.125988   Chr21 : 33,179,371
0.000 1.000 0.000
rs2833607 lBF = -0.126918   Chr21 : 33,381,040
0.000 1.000 0.000
rs914187 lBF = -0.12957   Chr21 : 42,619,749
0.000 1.000 0.000
rs6517656 lBF = -0.130665   Chr21 : 42,583,738
0.000 1.000 0.000
rs425215 lBF = -0.131694   Chr21 : 43,707,101
0.000 1.000 0.000
rs9305339 lBF = -0.134502   Chr21 : 29,275,627
0.000 1.000 0.000
rs1209950 lBF = -0.135202   Chr21 : 40,173,528
0.000 1.000 0.000
rs8133932 lBF = -0.135411   Chr21 : 47,211,085
0.000 1.000 0.000
rs10854398 lBF = -0.138334   Chr21 : 41,021,752
0.000 1.000 0.000
rs2838923 lBF = -0.138985   Chr21 : 46,846,944
0.000 1.000 0.000
rs1547374 lBF = -0.144708   Chr21 : 43,778,895
0.000 1.000 0.000
rs2823093 lBF = -0.146526   Chr21 : 16,520,832
0.000 1.000 0.000
rs9981861 lBF = -0.146751   Chr21 : 41,415,044
0.000 1.000 0.000
rs372883 lBF = -0.149456   Chr21 : 30,717,737
0.000 1.000 0.000
rs11700462 lBF = -0.153274   Chr21 : 38,817,812
0.000 1.000 0.000
rs2823962 lBF = -0.153448   Chr21 : 18,046,232
0.000 1.000 0.000
rs2823357 lBF = -0.15607   Chr21 : 16,914,905
0.000 1.000 0.000
rs2827312 lBF = -0.157179   Chr21 : 23,631,676
0.000 1.000 0.000
rs73194058 lBF = -0.159459   Chr21 : 34,764,288
0.000 1.000 0.000
rs67900830 lBF = -0.161217   Chr21 : 44,615,872
0.000 1.000 0.000
rs1735884 lBF = -0.161398   Chr21 : 21,820,408
0.000 1.000 0.000
rs2838088 lBF = -0.161591   Chr21 : 43,092,201
0.000 1.000 0.000
rs234720 lBF = -0.162516   Chr21 : 44,445,292
0.000 1.000 0.000
rs8133949 lBF = -0.163479   Chr21 : 43,421,114
0.000 1.000 0.000
rs2825388 lBF = -0.163847   Chr21 : 20,536,649
0.000 1.000 0.000
rs2823048 lBF = -0.165137   Chr21 : 16,462,268
0.000 1.000 0.000
rs2229741 lBF = -0.166489   Chr21 : 16,340,289
0.000 1.000 0.000
rs3788013 lBF = -0.16819   Chr21 : 43,841,328
0.000 1.000 0.000
rs1598848 lBF = -0.170229   Chr21 : 28,946,276
0.000 1.000 0.000
rs2835810 lBF = -0.170805   Chr21 : 38,932,778
0.000 1.000 0.000
rs8129913 lBF = -0.171112   Chr21 : 27,064,339
0.000 1.000 0.000
rs4818225 lBF = -0.173335   Chr21 : 42,629,895
0.000 1.000 0.000
rs13046373 lBF = -0.175755   Chr21 : 32,060,490
0.000 1.000 0.000
rs9977018 lBF = -0.181144   Chr21 : 43,036,969
0.000 1.000 0.000
rs11911275 lBF = -0.182681   Chr21 : 44,593,140
0.000 1.000 0.000
rs2823053 lBF = -0.18305   Chr21 : 16,465,149
0.000 1.000 0.000
rs2834655 lBF = -0.184399   Chr21 : 36,238,507
0.000 1.000 0.000
rs2830840 lBF = -0.185335   Chr21 : 28,665,347
0.000 1.000 0.000
rs2828478 lBF = -0.187239   Chr21 : 25,105,211
0.000 1.000 0.000
rs2837253 lBF = -0.187879   Chr21 : 41,221,256
0.000 1.000 0.000
rs881827 lBF = -0.189475   Chr21 : 48,019,868
0.000 1.000 0.000
rs455804 lBF = -0.1918   Chr21 : 31,146,169
0.000 1.000 0.000
rs1734920 lBF = -0.192071   Chr21 : 41,344,911
0.000 1.000 0.000
rs62229266 lBF = -0.196851   Chr21 : 37,460,271
0.000 1.000 0.000
rs2776353 lBF = -0.196872   Chr21 : 43,089,017
0.000 1.000 0.000
rs2828785 lBF = -0.1982   Chr21 : 25,437,505
0.000 1.000 0.000
rs2834188 lBF = -0.199085   Chr21 : 34,689,253
0.000 1.000 0.000
rs459482 lBF = -0.19916   Chr21 : 42,793,791
0.000 1.000 0.000
rs1003719 lBF = -0.200585   Chr21 : 38,491,095
0.000 1.000 0.000
rs363598 lBF = -0.204975   Chr21 : 31,013,159
0.000 1.000 0.000
rs45430 lBF = -0.207019   Chr21 : 42,746,081
0.000 1.000 0.000
rs6517368 lBF = -0.207558   Chr21 : 38,007,943
0.000 1.000 0.000
rs6517329 lBF = -0.209681   Chr21 : 37,481,477
0.000 1.000 0.000
rs643608 lBF = -0.21019   Chr21 : 44,768,562
0.000 1.000 0.000
rs11910494 lBF = -0.215618   Chr21 : 33,296,113
0.000 1.000 0.000
rs2837857 lBF = -0.218872   Chr21 : 42,216,955
0.000 1.000 0.000
rs234709 lBF = -0.21931   Chr21 : 44,486,964
0.000 1.000 0.000
rs4817775 lBF = -0.221895   Chr21 : 37,485,062
0.000 1.000 0.000
rs2410182 lBF = -0.222079   Chr21 : 41,180,076
0.000 1.000 0.000
rs1041449 lBF = -0.22655   Chr21 : 42,901,421
0.000 1.000 0.000
rs1888414 lBF = -0.229551   Chr21 : 21,777,730
0.000 1.000 0.000
rs2837828 lBF = -0.230002   Chr21 : 42,174,960
0.000 1.000 0.000
rs2830487 lBF = -0.237741   Chr21 : 28,146,189
0.000 1.000 0.000
rs2833610 lBF = -0.241956   Chr21 : 33,385,186
0.000 1.000 0.000
rs982274 lBF = -0.259844   Chr21 : 19,479,731
0.000 1.000 0.000

This table lists the top 312 variants ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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